43,184 results match your criteria Pediatrics[Journal]


Beyond an Obvious Cause of Cholestasis in a Toddler: Compound Heterozygosity for Mutations.

Pediatrics 2019 Apr 23. Epub 2019 Apr 23.

Institut für Pathologie, Medizinische Universität Graz, Graz, Austria.

A 27-month-old girl presented with a short history of jaundice initially attributed to drug-induced liver injury. During the preceding 20 days, she had received a 10-day course of cefprozil and 2 doses of a homeopathic preparation of cantharidin for cystitis. Severe conjugated hyperbilirubinemia was present with normal γ-glutamyl transpeptidase activity. Read More

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http://dx.doi.org/10.1542/peds.2018-2146DOI Listing

Mediators of Improved Adherence to Infant Safe Sleep Using a Mobile Health Intervention.

Pediatrics 2019 Apr 23. Epub 2019 Apr 23.

Family Medicine, School of Medicine and.

Objectives: To determine mediators of improvements in infant safe-sleep (SS) practices in a mobile health intervention.

Methods: In a cluster-randomized controlled trial, mothers received SS intervention or breastfeeding control videos for 60 days. Maternal responses about infant sleep position and location (outcomes) and mediators (attitudes, perceived social norms, and perceived control) from the theory of planned behavior were assessed. Read More

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http://dx.doi.org/10.1542/peds.2018-2799DOI Listing

Prenatal diagnosis of congenital megalourethra with imperforate anus.

BMC Pediatr 2019 Apr 23;19(1):123. Epub 2019 Apr 23.

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taipei, Republic of China.

Background: Congenital megalourethra is a rare prenatal finding while prenatal diagnosis of imperforate anus poses high challenge. This is the first prenatally ultrasound diagnosed case which had congenital megalourethra and imperforate anus. This case demonstrated the possibility of using the prenatal imaging findings to evaluate the postnatal prognostic outcomes in multi-organ anomalies. Read More

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http://dx.doi.org/10.1186/s12887-019-1510-yDOI Listing

Respiratory severity score as a predictive factor for severe bronchopulmonary dysplasia or death in extremely preterm infants.

BMC Pediatr 2019 Apr 23;19(1):121. Epub 2019 Apr 23.

Department of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82, Gumi-ro 173 beon-gil, Bundang-gu, Seongnam-si, 13620, South Korea.

Background: Despite significant advances in neonatology, bronchopulmonary dysplasia (BPD) remains the most common cause of serious morbidity and mortality in premature infants. The aim of the present study was to determine associations between the respiratory severity score (RSS) with death or BPD in premature infants.

Methods: This was a retrospective study conducted between January 2010 and December 2014. Read More

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http://dx.doi.org/10.1186/s12887-019-1492-9DOI Listing

Childhood undernutrition in three disadvantaged East African Districts: a multinomial analysis.

BMC Pediatr 2019 Apr 23;19(1):118. Epub 2019 Apr 23.

World Vision International, Southern Africa Regional Office, H100, Mbabane, Swaziland.

Background: Undernutrition is an important public health indicator for monitoring nutritional status and survival. In spite of its importance, undernutrition is a significant problem health problem in many East African communities. The aim of this study was to identify factors associated with childhood undernutrition in three disadvantaged East African Districts. Read More

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http://dx.doi.org/10.1186/s12887-019-1482-yDOI Listing

Faster recovery and reduced paracetamol use - a meta-analysis of EPs 7630 in children with acute respiratory tract infections.

BMC Pediatr 2019 Apr 23;19(1):119. Epub 2019 Apr 23.

Clinic for Paediatrics, Evangelic Hospital Hamm, Hamm, Germany.

Objective: Fever is a very common adaptive immune response in acute respiratory tract disorders during infancy. Antipyretic / analgesic drugs such as paracetamol (acetaminophen) are widely used to improve the comfort of the child but may cause medically unneeded antipyresis and rare but potentially serious side effects. We assess whether treatment with Pelargonium sidoides extract EPs 7630 reduces the administration of paracetamol in children with acute tonsillopharyngitis (ATP) or acute bronchitis (AB). Read More

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http://dx.doi.org/10.1186/s12887-019-1473-zDOI Listing

Body mass index and dental caries in young people: a systematic review.

BMC Pediatr 2019 Apr 23;19(1):122. Epub 2019 Apr 23.

Public Health England, South West, Follaton House, Plymouth Road, Totnes, Devon, TQ9 5NE, UK.

Background: Obesity and caries in young people are issues of public health concern. Even though research into the relationship between the two conditions has been conducted for many years, to date the results remain equivocal. The aim of this paper was to determine the nature of the relationship between Body Mass Index (BMI) and caries in children and adolescents, by conducting a systematic review of the published literature. Read More

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http://dx.doi.org/10.1186/s12887-019-1511-xDOI Listing

Anthropometric measurements can identify small for gestational age newborns: a cohort study in rural Tanzania.

BMC Pediatr 2019 Apr 23;19(1):120. Epub 2019 Apr 23.

Centre for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Blegdamsvej 3B, Building 07-11-56, 2200, Copenhagen, Denmark.

Background: Small-for-gestational-age (SGA) is associated with increased neonatal mortality and morbidity. In low and middle income countries an accurate gestational age is often not known, making the identification of SGA newborns difficult. Measuring foot length, chest circumference and mid upper arm circumference (MUAC) of the newborn have previously been shown to be reasonable methods for detecting low birth weight (< 2500 g) and prematurity (gestational age <  37 weeks). Read More

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https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887
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http://dx.doi.org/10.1186/s12887-019-1500-0DOI Listing
April 2019
1 Read

Self-Reported Use of Tobacco, E-cigarettes, and Marijuana Versus Urinary Biomarkers.

Pediatrics 2019 Apr 22. Epub 2019 Apr 22.

Division of Cancer Prevention and Population Sciences, Department of Health Behavior, Roswell Park Comprehensive Center, Buffalo, New York.

Background: Surveys have been instrumental in describing adolescent use of tobacco, electronic cigarettes (e-cigarettes), and marijuana. However, objective biomarker data are lacking. We compared adolescent self-reported use to urinary biomarkers. Read More

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http://dx.doi.org/10.1542/peds.2018-3531DOI Listing

Sleep-Related Infant Suffocation Deaths Attributable to Soft Bedding, Overlay, and Wedging.

Pediatrics 2019 Apr 22. Epub 2019 Apr 22.

Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia.

Background: Unintentional suffocation is the leading cause of injury death among infants <1 year old in the United States, with 82% being attributable to accidental suffocation and strangulation in bed. Understanding the circumstances surrounding these deaths may inform prevention strategies.

Methods: We analyzed data from the population-based Sudden Unexpected Infant Death Case Registry from 2011 to 2014. Read More

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http://dx.doi.org/10.1542/peds.2018-3408DOI Listing

Transporting Children With Special Health Care Needs.

Pediatrics 2019 Apr 22. Epub 2019 Apr 22.

Children with special health care needs should have access to proper resources for safe transportation as do typical children. This policy statement reviews important considerations for transporting children with special health care needs and provides current guidance for the protection of children with specific health care needs, including those with airway obstruction, orthopedic conditions or procedures, developmental delays, muscle tone abnormalities, challenging behaviors, and gastrointestinal disorders. Read More

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http://dx.doi.org/10.1542/peds.2019-0724DOI Listing

Health Supervision for Children With Neurofibromatosis Type 1.

Pediatrics 2019 Apr 22. Epub 2019 Apr 22.

Neurofibromatosis type 1 (NF1) is a multisystem disorder that primarily involves the skin and peripheral nervous system. Its population prevalence is approximately 1 in 3000. The condition is usually recognized in early childhood, when pigmentary manifestations emerge. Read More

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http://dx.doi.org/10.1542/peds.2019-0660DOI Listing

Parental age and developmental milestones: pilot study indicated a role in understanding ADHD severity in Indian probands.

BMC Pediatr 2019 Apr 22;19(1):117. Epub 2019 Apr 22.

Manovikas Biomedical Research and Diagnostic Centre, Manovikas Kendra, 482, Madudah, Plot I-24, Sec.-J, E.M. Bypass, Kolkata, 700107, India.

Background: In different ethnic groups, birth related factors have shown significant influence in the etiology of Attention deficit hyperactivity disorder (ADHD). Based on these interesting findings, we aimed to investigate association between different pre- and post natal variables and ADHD associated traits in Indian subjects.

Methods: ADHD Probands recruited based on the DSM-IV, were assessed by the Conner's Parent Rating Scale for behavioral problem (BPr), inattention (IA), hyperactivity (HA) and ADHD index (AI). Read More

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http://dx.doi.org/10.1186/s12887-019-1483-xDOI Listing

Lifestyle Behavior and Mental Health in Early Adolescence.

Pediatrics 2019 Apr 19. Epub 2019 Apr 19.

Population Health Intervention Research Unit, School of Public Health, Edmonton, University of Alberta, Edmonton, Canada;

Background And Objectives: Mental illnesses affect >15% of Canadian adolescents. New preventive strategies are critically needed. We examined the associations of meeting established recommendations for diet, physical activity, sleep, and sedentary behavior in childhood with mental illness in adolescence. Read More

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2018-3307DOI Listing
April 2019
1 Read

Postvaccination Febrile Seizure Severity and Outcome.

Pediatrics 2019 Apr 19. Epub 2019 Apr 19.

National Centre for Immunisation Research and Surveillance, Children's Hospital at Westmead, Sydney, Australia.

Background: Febrile seizures (FSs) are a common pediatric condition caused by a sudden rise in temperature, affecting 3% to 5% of children aged ≤6 years. Although vaccination can cause FSs, little is known on whether FSs occurring in the time soon after vaccination (vaccine-proximate febrile seizures [VP-FSs] differ clinically from non-vaccine-proximate febrile seizures [NVP-FSs]). We compared the clinical profile and outcomes of VP-FS to NVP-FS. Read More

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http://dx.doi.org/10.1542/peds.2018-2120DOI Listing
April 2019
6 Reads

Variation in hospital charges in patients with external ventricular drains: comparison between the intensive care and surgical floor settings.

J Neurosurg Pediatr 2019 Apr 19:1-6. Epub 2019 Apr 19.

3Department of Neurosurgery, University of Washington School of Medicine, Seattle, Washington.

OBJECTIVEPlacement of an external ventricular drain (EVD) is a common and potentially life-saving neurosurgical procedure, but the economic aspect of EVD management and the relationship to medical expenditure remain poorly studied. Similarly, interinstitutional practice patterns vary significantly. Whereas some institutions require that patients with EVDs be monitored strictly within the intensive care unit (ICU), other institutions opt primarily for management of EVDs on the surgical floor. Read More

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https://thejns.org/view/journals/j-neurosurg-pediatr/aop/art
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http://dx.doi.org/10.3171/2019.2.PEDS18545DOI Listing
April 2019
2 Reads

Hydrocephalus-induced neurogenic stunned myocardium and cardiac arrest in a child: completely reversed with CSF diversion.

J Neurosurg Pediatr 2019 Apr 19:1-6. Epub 2019 Apr 19.

Neurogenic stunned myocardium (NSM) is a potentially fatal cause of sudden cardiogenic dysfunction due to an acute neurological event, most commonly aneurysmal subarachnoid hemorrhage in adults. Only two pediatric cases of hydrocephalus-induced NSM have been reported. Here the authors report a third case in a 14-year-old boy who presented with severe headache, decreased level of consciousness, and shock in the context of acute hydrocephalus secondary to fourth ventricular outlet obstruction 3 years after standard-risk medulloblastoma treatment. Read More

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http://dx.doi.org/10.3171/2019.2.PEDS18711DOI Listing

Intracranial volume versus static and pulsatile intracranial pressure values in children with craniosynostosis.

J Neurosurg Pediatr 2019 Apr 19:1-9. Epub 2019 Apr 19.

1Department of Neurosurgery, Oslo University Hospital-Rikshospitalet, Oslo, Norway; and.

OBJECTIVEReduced intracranial volume (ICV) and raised intracranial pressure (ICP) are assumed to be principal pathophysiological mechanisms in childhood craniosynostosis. This study examined the association between ICV and ICP and whether ICV can be used to estimate the ICP.METHODSThe authors analyzed ICV and ICP measurements from children with craniosynostosis without concurrent hydrocephalus and from age-matched individuals without craniosynostosis who underwent diagnostic ICP measurement. Read More

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http://dx.doi.org/10.3171/2019.2.PEDS18767DOI Listing
April 2019
1 Read

Clinical outcome of V-Y flap with latissimus dorsi and gluteal advancement for treatment of large thoracolumbar myelomeningocele defects: a comparative study.

J Neurosurg Pediatr 2019 Apr 19:1-10. Epub 2019 Apr 19.

1Department of Neurosurgery.

OBJECTIVESurgical repair and closure of myelomeningocele (MMC) defects are important and vital, as the mortality rate is as high as 65%-70% in untreated patients. Closure of large MMC defects is challenging for pediatric neurosurgeons and plastic surgeons. The aim of the current study is to report the operative characteristics and outcome of a series of Iranian patients with large MMC defects utilizing the V-Y flap and with latissimus dorsi or gluteal muscle advancement. Read More

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http://dx.doi.org/10.3171/2019.1.PEDS18232DOI Listing

Predictors of endoscopic third ventriculostomy ostomy status in patients who experience failure of endoscopic third ventriculostomy with choroid plexus cauterization.

J Neurosurg Pediatr 2019 Apr 19:1-6. Epub 2019 Apr 19.

1Surgical Outcomes Center for Kids, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville.

OBJECTIVEAt failure of endoscopic third ventriculostomy (ETV) with choroid plexus cauterization (CPC), the ETV ostomy may be found to be closed or open. Failure with a closed ostomy may indicate a population that could benefit from evolving techniques to keep the ostomy open and may be candidates for repeat ETV, whereas failure with an open ostomy may be due to persistently abnormal CSF dynamics. This study seeks to identify clinical and radiographic predictors of ostomy status at the time of ETV/CPC failure. Read More

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https://thejns.org/view/journals/j-neurosurg-pediatr/aop/art
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http://dx.doi.org/10.3171/2019.2.PEDS18743DOI Listing
April 2019
1 Read

Ulnar Nerve Injuries Post Closed Forearm Fractures in Paediatric Population: A Review of the Literature.

Clin Med Insights Pediatr 2019 8;13:1179556519841876. Epub 2019 Apr 8.

Department of Orthopaedics and Traumatology, General Hospital of Agios Nikolaos, Crete, Greece.

Ulnar nerve injury as a result of closed forearm fractures in children is a rare but disastrous complication, affecting significantly the function of the upper extremity. The management of these injuries is still controversial in the literature. This is a review of small case series and case reports, in which an algorithm of treatment is proposed. Read More

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http://dx.doi.org/10.1177/1179556519841876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454652PMC

Colchicine: An Impressive Effect on Posttransplant Capillary Leak Syndrome and Renal Failure.

Pediatrics 2019 Apr 18. Epub 2019 Apr 18.

University of Turin, Turin, Italy; and.

Capillary leak syndrome is a critical condition occasionally occurring posttransplant and is characterized by acute endothelial hyperpermeability leading to systemic protein-rich fluid extravasation and consequent hypovolemia, hypoperfusion, and acute kidney injury. Treatment is merely supportive and is based on osmotic drugs, diuretics, continuous renal replacement therapy, and surgical drainage. However, removal of the underlying inflammatory cause is mandatory to achieve stable resolution. Read More

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2018-2820DOI Listing
April 2019
1 Read

Adolescent and Young Adult Cancer Patients' Experiences With Treatment Decision-making.

Pediatrics 2019 Apr 18. Epub 2019 Apr 18.

Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, Massachusetts.

Background: Adolescents and young adults (AYAs) with cancer generally want to engage in decision-making but are not always able to do so. We evaluated cancer treatment decision-making among AYAs, including decisional engagement and regret.

Methods: We surveyed 203 AYA patients with cancer aged 15 to 29 (response rate 74%) treated at a large academic center and their oncologists. Read More

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http://dx.doi.org/10.1542/peds.2018-2800DOI Listing
April 2019
1 Read

Association between anxiety and aggression in adolescents: a cross-sectional study.

BMC Pediatr 2019 Apr 18;19(1):115. Epub 2019 Apr 18.

College of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-Gu, Seoul, 03760, South Korea.

Background: The purpose of this study was to investigate the relationship between anxiety proneness and aggressive behavior in adolescents.

Methods: A quantitative, large scale cross-sectional study was conducted in Korea. The survey questionnaire included general health behavior and scales for assessing anxiety (Revised Children's Manifest Anxiety Scale; RCMAS) and aggressive behavior (The Aggression Questionnaire; AQ) in adolescents. Read More

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https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887
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http://dx.doi.org/10.1186/s12887-019-1479-6DOI Listing
April 2019
1 Read

Digenetic inheritance of SLC12A3 and CLCNKB genes in a Chinese girl with Gitelman syndrome.

BMC Pediatr 2019 Apr 18;19(1):114. Epub 2019 Apr 18.

The First Affiliated Hospital of Zhejiang University, Hangzhou, China.

Background: Gitelman syndrome (GS) is an autosomal recessive disorder and mild variant of classic Bartter syndrome. The latter is caused by defects in the genes CLCNKB and/or CLCNKA (chloride voltage-gated channel Ka and Kb). Patients with GS usually have loss-of-function mutations in SLC12A3. Read More

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http://dx.doi.org/10.1186/s12887-019-1498-3DOI Listing
April 2019
2 Reads

Parental smoking and blood pressure in children and adolescents: a national cross-sectional study in China.

BMC Pediatr 2019 Apr 18;19(1):116. Epub 2019 Apr 18.

Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, Xueyuan Road 38, Haidian District, Beijing, 100191, China.

Background: Current evidence on the health effects of passive smoking on childhood blood pressure is limited and inconsistent. We investigated the associations between exposure to parental smoking and blood pressure in children and adolescents.

Methods: A cross-sectional analysis was performed in a national sample of 42,745 children and adolescents (50. Read More

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http://dx.doi.org/10.1186/s12887-019-1505-8DOI Listing

Blood Lead Levels Among Resettled Refugee Children in Select US States, 2010-2014.

Pediatrics 2019 Apr 17. Epub 2019 Apr 17.

Immigrant, Refugee, and Migrant Health Branch, Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, Georgia.

Background: Elevated blood lead levels (EBLLs; ≥5 µg/dL) are more prevalent among refugee children resettled in the United States than the general US population and contribute to permanent health and neurodevelopmental problems. The Centers for Disease Control and Prevention recommends screening of refugee children aged 6 months to 16 years on arrival in the United States and retesting those aged 6 months to 6 years between 3- and 6-months postarrival.

Methods: We analyzed EBLL prevalence among refugee children aged 6 months to 16 years who received a domestic refugee medical examination between January 1, 2010 and September 30, 2014. Read More

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http://dx.doi.org/10.1542/peds.2018-2591DOI Listing
April 2019
5.473 Impact Factor

Preventing Harm on Arrival: Lead Prevention in Newly Resettled Pediatric Refugees.

Pediatrics 2019 Apr 17. Epub 2019 Apr 17.

The Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, Vermont.

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http://dx.doi.org/10.1542/peds.2018-3567DOI Listing

Clinical predictors of symptom resolution for children and adolescents with sport-related concussion.

J Neurosurg Pediatr 2019 Apr 16:1-8. Epub 2019 Apr 16.

1Sports Medicine Center and.

OBJECTIVEThe goal of this study was to determine which variables assessed during an initial clinical evaluation for concussion are independently associated with time until symptom resolution among pediatric patients.METHODSData collected from a prospective clinical registry of pediatric patients with concussion were analyzed. The primary outcome variable was time from injury until symptom resolution. Read More

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http://dx.doi.org/10.3171/2018.11.PEDS18626DOI Listing
April 2019
1 Read

Provisional Validation of a Pediatric Early Warning Score for Resource-Limited Settings.

Pediatrics 2019 Apr 16. Epub 2019 Apr 16.

Department of Pediatrics, School of Medicine, Yale University, New Haven, Connecticut.

Background And Objectives: The use of Pediatric Early Warning Scores is becoming widespread to identify and rapidly respond to patients with deteriorating conditions. The ability of Pediatric Early Warning Scores to identify children at high risk of deterioration or death has not, however, been established in resource-limited settings.

Methods: We developed the Pediatric Early Warning Score for Resource-Limited Settings (PEWS-RL) on the basis of expert opinion and existing scores. Read More

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http://dx.doi.org/10.1542/peds.2018-3657DOI Listing

Forewarned Is Forearmed.

Pediatrics 2019 Apr 16. Epub 2019 Apr 16.

Paediatrics and Child Health, College of Medicine, University of Malawi, Blantyre, Malawi

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http://dx.doi.org/10.1542/peds.2018-4058DOI Listing

Intellectual Disability and Adolescent Bariatric Surgery: Support of Special Eligibility Criteria.

Authors:
Marc P Michalsky

Pediatrics 2019 Apr 15. Epub 2019 Apr 15.

College of Medicine, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio

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http://dx.doi.org/10.1542/peds.2018-4112DOI Listing
April 2019
3 Reads

Sleeve Gastrectomy for Youth With Cognitive Impairment or Developmental Disability.

Pediatrics 2019 Apr 15. Epub 2019 Apr 15.

Center for Translational Research, Children's National Health System, Washington, District of Columbia.

Background And Objectives: Youth with cognitive impairment or developmental disability (CI/DD) face higher rates of obesity and secondary medical issues. Bariatric surgery may be a helpful tool for health improvement because it has been shown efficacious for adolescents. We aim to contribute to literature regarding bariatric surgery for adolescents with CI/DD and explore the association between cognitive functioning and weight loss outcomes. Read More

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2018-2908DOI Listing
April 2019
1 Read

Teenagers, Sexting, and the Law.

Pediatrics 2019 Apr 15. Epub 2019 Apr 15.

University of Calgary, Calgary, Canada; and.

The phenomenon of teen sexting emerged as a result of the proliferation of digital technology. More than 40 studies have established that teen sexting occurs relatively frequently and is a rising trend, commensurate with the ubiquity of smartphone ownership in teens. Studies have shown that sexting is associated with incidences of increased sexual behavior. Read More

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http://dx.doi.org/10.1542/peds.2018-3183DOI Listing
April 2019
7 Reads

Quick assessment with controlled attenuation parameter for hepatic steatosis in children based on MRI-PDFF as the gold standard.

BMC Pediatr 2019 Apr 15;19(1):112. Epub 2019 Apr 15.

Department of Radiology and Research Institute of Radiological Science, Severance Children's Hospital, Yonsei University College of Medicine, 50-1Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

Background: Controlled attenuation parameter (CAP) is a recently introduced, non-invasive and quantitative method to evaluate hepatic steatosis demonstrated in adults, but limited in obesity and not well evaluated in children. The aim of this study was to investigate the diagnostic performance for assessing hepatic steatosis grades using CAP in children based on MR proton density fat fraction (PDFF).

Methods: Children evaluated for non-alcoholic fatty liver disease (NAFLD) who were assessed for PDFF and CAP were enrolled retrospectively. Read More

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http://dx.doi.org/10.1186/s12887-019-1485-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463656PMC
April 2019
1 Read

Household, maternal, and child related determinants of hemoglobin levels of Ethiopian children: hierarchical regression analysis.

BMC Pediatr 2019 Apr 15;19(1):113. Epub 2019 Apr 15.

Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Background: Anemia remains a major public health problem among children under five years old in Ethiopia, rising unexpectedly from 44% national prevalence in 2011 to 57% in 2016. In this study, we investigated the household, maternal and child-related dietary and non-dietary factors associated with hemoglobin (Hb) level of infants and young children.

Method: We analyzed data from a nationally representative sample of 2902 children aged 6-23 months, included in the 2016 Ethiopian demographic and health survey (EDHS). Read More

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http://dx.doi.org/10.1186/s12887-019-1476-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466676PMC

Gestational Age, Birth Weight, and Outcomes Six Years After the Norwood Procedure.

Pediatrics 2019 Apr 12. Epub 2019 Apr 12.

Department of Pediatrics, The University of Utah, Salt Lake City, Utah.

Background: Preterm delivery and low birth weight (LBW) are generally associated with worse outcomes in hypoplastic left heart syndrome (HLHS), but an individual preterm or small neonate may do well. We sought to explore the interactions between gestational age, birth weight, and birth weight for gestational age with intermediate outcomes in HLHS.

Methods: We analyzed survival, growth, neurodevelopment, length of stay, and complications to age 6 years in subjects with HLHS from the Single Ventricle Reconstruction trial. Read More

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2018-2577DOI Listing
April 2019
1 Read

Foreign-Body Ingestions of Young Children Treated in US Emergency Departments: 1995-2015.

Pediatrics 2019 Apr 12. Epub 2019 Apr 12.

Center for Injury Research and Policy, The Research Institute, Nationwide Children's Hospital, Columbus, Ohio; and.

Objectives: To describe the epidemiology of foreign-body ingestions (FBIs) of children <6 years of age who were treated in US emergency departments from 1995 to 2015.

Methods: We performed a retrospective analysis using data from the National Electronic Injury Surveillance System for children <6 years of age who were treated because of concern of FBI from 1995 to 2015. National estimates were generated from the 29 893 actual cases reviewed. Read More

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http://dx.doi.org/10.1542/peds.2018-1988DOI Listing
April 2019
11 Reads

Enterostomy complications in necrotizing enterocolitis (NEC) surgery, a retrospective chart review at Odense University Hospital.

BMC Pediatr 2019 Apr 13;19(1):110. Epub 2019 Apr 13.

Surgical Department A, Odense University Hospital, J.B. Winsløws Vej 4, 5000, Odense C, Denmark.

Background: The aim was to investigate the incidence of postoperative complications to surgery for necrotizing enterocolitis (NEC) with primary focus on enterostomy related complications.

Methods: A retrospective chart review of surgically treated NEC during the period from 2008 to 2014 was performed. Enterostomy with secondary anastomosis was our standard treatment. Read More

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http://dx.doi.org/10.1186/s12887-019-1488-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461813PMC

Lethal perinatal hypophosphatasia caused by a novel compound heterozygous mutation: a case report.

BMC Pediatr 2019 Apr 13;19(1):109. Epub 2019 Apr 13.

Department of Neonatal Intensive Care Unit, The First Hospital of Tsinghua University, No. 6, Jiuxianqiao, Chaoyang District, Beijing, 100016, China.

Background: Hypophosphatasia (HPP) is a rare hereditary disorder characterized by defective bone and tooth mineralization and deficiency of tissue non-specific alkaline phosphatase (TNAP) activity. The clinical presentation of HPP is highly variable, and the prognosis for the infantile form is poor.

Case Presentation: This study reports a male infant diagnosed with lethal perinatal HPP. Read More

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http://dx.doi.org/10.1186/s12887-019-1478-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461808PMC

Survivorship care plan experiences among childhood acute lymphoblastic leukemia patients and their families.

BMC Pediatr 2019 Apr 13;19(1):111. Epub 2019 Apr 13.

Huntsman Cancer Institute, Cancer Control and Population Sciences, 2000 Circle of Hope, Salt Lake City, UT, 84112, USA.

Background: As survivorship care plan (SCP) use among childhood cancer survivors and their families has not been extensively researched, we report on their experiences with receiving an SCP after the completion of therapy.

Methods: Eligible patients had acute lymphoblastic leukemia, completed therapy, and had no evidence of disease at enrollment. Patients aged 7 or older (N = 13) and at least one parent (N = 23 for 20 total patients) were surveyed and completed assessments at enrollment (Time 1, T1), SCP delivery (Time 2, T2), and follow-up (Time 3, T3) (retention 90. Read More

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https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887
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http://dx.doi.org/10.1186/s12887-019-1464-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461822PMC
April 2019
7 Reads

A screening tool for psychological difficulties in children aged 6 to 36 months: cross-cultural validation in Kenya, Cambodia and Uganda.

BMC Pediatr 2019 Apr 12;19(1):108. Epub 2019 Apr 12.

Epicentre, 8 rue Saint Sabin, 75011, Paris, France.

Background: In low-resource settings, the lack of mental health professionals and cross-culturally validated screening instruments complicates mental health care delivery. This is especially the case for very young children. Here, we aimed to develop and cross-culturally validate a simple and rapid tool, the PSYCa 6-36, that can be administered by non-professionals to screen for psychological difficulties among children aged six to 36 months. Read More

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http://dx.doi.org/10.1186/s12887-019-1461-3DOI Listing

Reconstruction of the anterior craniocervical junction using an expandable cage after resection of a C1 chordoma in a 5-year-old child: case report.

J Neurosurg Pediatr 2019 Apr 12:1-4. Epub 2019 Apr 12.

1Section of Pediatric Neurosurgery, Riley Hospital for Children, Department of Neurological Surgery, Indiana University School of Medicine, Goodman Campbell Brain and Spine, Indianapolis, Indiana; and.

Chordomas are histologically benign tumors with local aggressive behavior. They arise from embryological remnants of the notochord at the clivus, mobile spine, and sacrum. Chordomas are rare tumors in the pediatric age group. Read More

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http://dx.doi.org/10.3171/2019.2.PEDS18752DOI Listing
April 2019
1 Read

Preoperative laboratory testing before pediatric neurosurgery: an NSQIP-Pediatrics analysis.

J Neurosurg Pediatr 2019 Apr 12:1-12. Epub 2019 Apr 12.

1Division of Pediatric Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland; and.

OBJECTIVESThe goal of this study was to evaluate clinical predictors of abnormal preoperative laboratory values in pediatric neurosurgical patients.METHODSData obtained in children who underwent a neurosurgical operation were extracted from the prospective National Surgical Quality Improvement Program-Pediatrics (NSQIP-P, 2012-2013) registry. Multivariable logistic regression evaluated predictors of preoperative laboratory values that might require further evaluation (white blood cell count < 2000/μl, hematocrit < 24%, platelet count < 100,000/μl, international normalized ratio > 1. Read More

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http://dx.doi.org/10.3171/2018.12.PEDS18441DOI Listing
April 2019
4 Reads

Development of bilateral dural arteriovenous fistulae following pial synangiosis for moyamoya syndrome: case report.

J Neurosurg Pediatr 2019 Apr 12:1-5. Epub 2019 Apr 12.

Departments of1Neurosurgery and.

Moyamoya syndrome predisposes patients to ischemic or hemorrhagic stroke due to progressive narrowing of intracranial vessels with subsequent small-vessel collateralization. Dural arteriovenous fistulae (DAVFs) are most commonly noted after venous sinus or cortical vein thrombosis and are believed to be primarily due to venous hypertension and elevated sinus pressures, although there is no known association with moyamoya syndrome, or with surgical treatment for moyamoya disease (MMD). The authors present the case of a 14-year-old girl with Down syndrome treated using pial synangiosis for MMD who subsequently was noted to have bilateral DAVFs. Read More

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http://dx.doi.org/10.3171/2019.2.PEDS18603DOI Listing
April 2019
4 Reads

Home Oxygen and 2-Year Outcomes of Preterm Infants With Bronchopulmonary Dysplasia.

Pediatrics 2019 Apr 11. Epub 2019 Apr 11.

Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Objectives: To compare medical and developmental outcomes over the first 2 years of life in extremely preterm infants with bronchopulmonary dysplasia (BPD) who were discharged on supplemental oxygen via nasal cannula with outcomes of infants with a similar severity of respiratory illness who were discharged breathing in room air.

Methods: We performed a propensity score-matched cohort study. Eligible infants were born at <27 weeks' gestation, were receiving supplemental oxygen or respiratory support at 36 weeks' postmenstrual age, and were assessed at 18 to 26 months' corrected age. Read More

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http://dx.doi.org/10.1542/peds.2018-2956DOI Listing

The Use of Oxygen at Discharge: Is It Safe? Is It Effective?

Pediatrics 2019 Apr 11. Epub 2019 Apr 11.

Division of Neonatology, Department of Pediatrics, Baylor University Medical Center and Pediatrix Medical Group, Dallas, Texas.

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2019-0372DOI Listing
April 2019
2 Reads

Prospective audit and feedback on antibiotic use in neonatal intensive care: a retrospective cohort study.

BMC Pediatr 2019 Apr 11;19(1):105. Epub 2019 Apr 11.

Antimicrobial Stewardship Program, Sinai Health System-University Health Network, 600 University Avenue, Toronto, ON, M5G 1X5, Canada.

Background: Antimicrobial stewardship programs potentially lead to appropriate antibiotic use, yet the optimal approach for neonates is uncertain. Such a program was implemented in a tertiary care neonatal intensive care unit in October 2012. We evaluated the impact of this program on antimicrobial use and its association with clinical outcomes. Read More

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http://dx.doi.org/10.1186/s12887-019-1481-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458619PMC

Heterozygous familial hypercholesterolaemia in a pair of identical twins: a case report and updated review.

BMC Pediatr 2019 Apr 11;19(1):106. Epub 2019 Apr 11.

Institute for Pathology, Laboratory and Forensic Medicine (I-PPerForM), Universiti Teknologi MARA (UiTM), Sungai Buloh Campus, Jalan Hospital, 47000, Sungai Buloh, Selangor, Malaysia.

Background: Familial hypercholesterolaemia (FH) is the most common inherited metabolic disease with an autosomal dominant mode of inheritance. It is characterised by raised serum levels of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-c), leading to premature coronary artery disease. Children with FH are subjected to early and enhanced atherosclerosis, leading to greater risk of coronary events, including premature coronary artery disease. Read More

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http://dx.doi.org/10.1186/s12887-019-1474-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458607PMC
April 2019
1 Read

Parental support in promoting children's health behaviours and preventing overweight and obesity - a long-term follow-up of the cluster-randomised healthy school start study II trial.

BMC Pediatr 2019 Apr 11;19(1):104. Epub 2019 Apr 11.

Department of Public Health Sciences, Karolinska Institutet, 171 77, Stockholm, Sweden.

Background: Effects of obesity prevention interventions in early childhood are only meaningful if they are sustained over time, but long-term follow-up studies are rare. The school-based cluster-randomised Healthy School Start (HSS) trial aimed at child health promotion and obesity prevention through parental support was carried out in 31 pre-school classes (378 families) in disadvantaged areas in Sweden during 2012-2013. Post-intervention results showed intervention effects on intake of unhealthy foods and drinks, and lower BMI-sds in children with obesity at baseline. Read More

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http://dx.doi.org/10.1186/s12887-019-1467-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458763PMC
April 2019
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