11,747 results match your criteria Pediatric Research[Journal]


Early life antecedents of positive child health among 10-year-old children born extremely preterm.

Pediatr Res 2019 Apr 20. Epub 2019 Apr 20.

Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Objective: To identify modifiable antecedents during pre-pregnancy and pregnancy windows associated with a positive child health at 10 years of age.

Study Design: Data on 889 children enrolled in the Extremely Low Gestational Age Newborn (ELGAN) study in 2002-2004 were analyzed for associations between potentially modifiable maternal antecedents during pre-pregnancy and pregnancy time windows and a previously described positive child health index (PCHI) score at 10 years of age. Stratification by race was also investigated for associations with investigated antecedents. Read More

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http://www.nature.com/articles/s41390-019-0404-x
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http://dx.doi.org/10.1038/s41390-019-0404-xDOI Listing
April 2019
1 Read

Placental programming of neuropsychiatric disease.

Pediatr Res 2019 Apr 19. Epub 2019 Apr 19.

Department of Pediatrics, Division of Neonatology, Children's Research Institute at Children's National Medical Center, Washington, DC, USA.

The placenta is vital for fetal growth, and compromised function is associated with abnormal development, especially of the brain. Linking placental function to brain development is a new field we have dubbed neuroplacentology. Approximately 380,000 infants in the United States each year abruptly lose placental support upon premature birth, and more than 10% of pregnancies are affected by more insidious placental dysfunction such as preeclampsia or infection. Read More

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http://dx.doi.org/10.1038/s41390-019-0405-9DOI Listing

Observed and calculated cerebral critical closing pressure are highly correlated in preterm infants.

Pediatr Res 2019 Apr 19. Epub 2019 Apr 19.

Department of Pediatrics, Neonatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.

Introduction: Cerebrovascular critical closing pressure (CrCP) is the arterial blood pressure (ABP) at which cerebral blood flow ceases. Preterm ABP is low and close to CrCP. The diastolic closing margin (diastolic ABP minus CrCP) has been associated with intraventricular hemorrhage in preterm infants. Read More

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http://dx.doi.org/10.1038/s41390-019-0403-yDOI Listing
April 2019
1 Read

Interaction between lifestyle behaviors and genetic polymorphism in SCAP gene on blood pressure among Chinese children.

Pediatr Res 2019 Apr 19. Epub 2019 Apr 19.

Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, 100191, Beijing, China.

Backgrounds: Previous studies had revealed that sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) rs12487736 polymorphism was associated with blood pressure (BP), but whether rs12487736 could interact with lifestyle behaviors on BP is unknown.

Methods: A case-control study with 1092 Chinese children was conducted.

Results: We found an interaction between rs12487736 and high calorie foods intake (fried chips/cakes/cookies) on systolic blood pressure (SBP) (P = 0. Read More

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http://dx.doi.org/10.1038/s41390-019-0402-zDOI Listing

Encephalopathy in neonates with subgaleal hemorrhage is a key predictor of outcome.

Pediatr Res 2019 Apr 18. Epub 2019 Apr 18.

Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Objective: Subgaleal hemorrhage (SGH) is reported to be associated with severe hemodynamic instability, coagulopathy, and even mortality. The importance of the presence or absence of neonatal encephalopathy in predicting SGH outcomes has not been explored. The aim of this study was to determine the relationship of clinical encephalopathy to short-term outcomes in neonates with SGH. Read More

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http://www.nature.com/articles/s41390-019-0400-1
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http://dx.doi.org/10.1038/s41390-019-0400-1DOI Listing
April 2019
1 Read

Association between neonatal serum bilirubin and childhood obesity in preterm infants.

Pediatr Res 2019 Apr 17. Epub 2019 Apr 17.

Department of Neonatology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Background: Serum bilirubin levels are inversely associated with obesity in adults. We are interested in whether neonatal jaundice is associated with childhood obesity in preterm infants.

Methods: Data were obtained from the US Collaborative Perinatal Project. Read More

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http://www.nature.com/articles/s41390-019-0399-3
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April 2019
2 Reads

Proposed endocrine funding priorities for the NICHD strategic plan: expert opinion from the Pediatric Endocrine Society.

Pediatr Res 2019 Apr 17. Epub 2019 Apr 17.

Division of Pediatric Endocrinology, UCLA Children's Discovery and Innovation Institute, David Geffen School of Medicine UCLA, Los Angeles, CA, USA.

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http://www.nature.com/articles/s41390-019-0401-0
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http://dx.doi.org/10.1038/s41390-019-0401-0DOI Listing
April 2019
1 Read

Correction: Associations of measures of systemic blood flow used in a randomized trial of delayed cord clamping in preterm infants.

Pediatr Res 2019 Apr 15. Epub 2019 Apr 15.

University of Sydney, Camperdown, Australia.

A correction to this paper has been published and can be accessed via a link at the top of the paper. Read More

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http://dx.doi.org/10.1038/s41390-019-0382-zDOI Listing

An exploratory study of parent-child association in sensory modulation disorder involving ADHD-related symptoms.

Pediatr Res 2019 Apr 15. Epub 2019 Apr 15.

Department of Occupational Therapy, School of Health Professions, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Sensory modulation disorder (SMD) and attention deficit hyperactivity disorder (ADHD) can co-occur and have overlapping symptoms, thus challenging practitioners. This study aimed to phenotypically explore parent-child associations in SMD, and the interplay between SMD- and ADHD-related symptoms in children with SMD and their parents.

Methods: A cross-sectional study examined 70 parents (n = 35 mothers; n = 35 fathers) and their 35 children with and without SMD, aged 4-6 years. Read More

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http://dx.doi.org/10.1038/s41390-019-0397-5DOI Listing
April 2019
1 Read

Ponderal index classifies obesity in children and adolescents more accurately than body mass index z-scores.

Pediatr Res 2019 Apr 15. Epub 2019 Apr 15.

Cardiovascular Investigation Clinic, Federal University of Espírito Santo (UFES), Vitória, ES, Brazil.

Background: We aimed to compare the accuracy of the ponderal index (PI) vs. BMI-for-age z-scores transformed (BMIz) in estimating body fat levels and classifying obesity in children and adolescents from a Brazilian urban population.

Methods: This is a cross-sectional study with 1149 participants (53. Read More

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http://dx.doi.org/10.1038/s41390-019-0395-7DOI Listing

Cystathionine γ-lyase deficiency enhances airway reactivity and viral-induced disease in mice exposed to side-stream tobacco smoke.

Pediatr Res 2019 Apr 15. Epub 2019 Apr 15.

Department of Pediatrics, Division of Clinical and Experimental Immunology and Infectious Diseases (CEIID), University of Texas Medical Branch, Galveston, TX, USA.

Background: Environmental tobacco smoke (ETS) is a known risk factor for severe respiratory syncytial virus (RSV) infections, yet the mechanisms of ETS/RSV comorbidity are largely unknown. Cystathionine γ-lyase regulates important physiological functions of the respiratory tract.

Methods: We used mice genetically deficient in the cystathionine γ-lyase enzyme (CSE), the major HS-generating enzyme in the lung to determine the contribution of HS to airway disease in response to side-stream tobacco smoke (TS), and to TS/RSV co-exposure. Read More

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http://dx.doi.org/10.1038/s41390-019-0396-6DOI Listing
April 2019
1 Read

Fetal growth restriction is associated with an altered cardiopulmonary and cerebral hemodynamic response to surfactant therapy in preterm lambs.

Pediatr Res 2019 Apr 14. Epub 2019 Apr 14.

The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.

Background: Efficacy of surfactant therapy in fetal growth restricted (FGR) preterm neonates is unknown.

Methods: Twin-bearing ewes underwent surgery at 105 days gestation to induce FGR in one twin by single umbilical artery ligation. At 123-127 days, catheters and flow probes were implanted in pulmonary and carotid arteries to measure flow and pressure. Read More

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http://dx.doi.org/10.1038/s41390-019-0398-4DOI Listing

Insights in Pediatric Research.

Pediatr Res 2019 Apr 12. Epub 2019 Apr 12.

Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, 21211, USA.

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http://www.nature.com/articles/s41390-019-0394-8
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April 2019
6 Reads

Increased risk of rickets but not fractures during childhood and adolescence following necrotizing enterocolitis among children born preterm in Sweden.

Pediatr Res 2019 Apr 10. Epub 2019 Apr 10.

Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Background: The aim was to clarify whether children born preterm with a history of necrotizing enterocolitis (NEC) had an increased risk of rickets, fractures, and/or vitamin D deficiency during childhood and adolescence compared to controls without NEC, matched for gestational age.

Methods: All infants born in Sweden between 1987 and 2009 with a gestational age <32 + 0 weeks and a diagnosis of NEC were identified. Totally, 465 children with a history of NEC and 2127 controls were included. Read More

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http://dx.doi.org/10.1038/s41390-019-0390-zDOI Listing

2018 Reviewer acknowledgments.

Authors:

Pediatr Res 2019 Apr 9. Epub 2019 Apr 9.

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http://dx.doi.org/10.1038/s41390-019-0381-0DOI Listing

Understanding the pathobiology in patent ductus arteriosus in prematurity-beyond prostaglandins and oxygen.

Pediatr Res 2019 Apr 9. Epub 2019 Apr 9.

Radboud Institute for Health Sciences, Amalia Children's Hospital, Division of Neonatology, Department of Pediatrics, Radboud university medical center, Geert Grooteplein zuid 10, Postal code 804, 6525 GA, Nijmegen, The Netherlands.

The ductus arteriosus (DA) is probably the most intriguing vessel in postnatal hemodynamic transition. DA patency in utero is an active state, in which prostaglandin E (PGE) and nitric monoxide (NO), play an important role. Since the DA gets programmed for postnatal closure as gestation advances, in preterm infants the DA frequently remains patent (PDA). Read More

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http://www.nature.com/articles/s41390-019-0387-7
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http://dx.doi.org/10.1038/s41390-019-0387-7DOI Listing
April 2019
2 Reads

Longitudinal changes in the gut microbiome of infants on total parenteral nutrition.

Pediatr Res 2019 Apr 9. Epub 2019 Apr 9.

Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.

Background: Animal studies suggest that total parenteral nutrition (TPN) may alter bacterial colonization of the intestinal tract and contribute to complications. Progressive changes in gut microbiome of infants receiving TPN are not well understood.

Methods: Infants with and without TPN/soy lipid were enrolled in a prospective, longitudinal study. Read More

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http://www.nature.com/articles/s41390-019-0391-y
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http://dx.doi.org/10.1038/s41390-019-0391-yDOI Listing
April 2019
1 Read

Interleukin 6 receptor alpha expression in PMNs isolated from prematurely born neonates: decreased expression is associated with differential mTOR signaling.

Pediatr Res 2019 Apr 9. Epub 2019 Apr 9.

Program in Molecular Medicine, University of Utah, Salt Lake City, UT, USA.

Background: Dysregulated inflammation leads to morbidity and mortality in neonates. Neutrophil-mediated inflammation can cause inflammatory tissue damage. The mammalian target of rapamycin (mTOR) pathway governs IL-6Rα protein expression in human neutrophils. Read More

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http://dx.doi.org/10.1038/s41390-019-0388-6DOI Listing
April 2019
4 Reads

Behavioural and cognitive outcomes following an early stress-reduction intervention for very preterm and extremely preterm infants.

Pediatr Res 2019 Apr 9. Epub 2019 Apr 9.

Parent-Infant Research Institute, Department of Clinical & Health Psychology, Austin Health, Melbourne, VIC, 3081, Australia.

Background: The landmark findings of the Mother-Infant Transaction Program (MITP) showing improved neurodevelopment of preterm infants following parent-sensitivity training delivered in the neonatal intensive care unit have not been consistently replicated. This study evaluated an MITP-type intervention in terms of neurobehavioural development to preschool age.

Methods: A randomised controlled trial involved 123 very preterm and extremely preterm infants allocated to either a parent-sensitivity intervention (PremieStart, n = 60) or to standard care (n = 63). Read More

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http://www.nature.com/articles/s41390-019-0385-9
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http://dx.doi.org/10.1038/s41390-019-0385-9DOI Listing
April 2019
5 Reads

Comparison of MRI and neurosonogram 1- and 2-dimensional morphological measurements of the newborn corpus callosum.

Pediatr Res 2019 Apr 9. Epub 2019 Apr 9.

Brighton and Sussex Medical School, Brighton, UK.

Background: Developmental abnormalities of the corpus callosum (CC) are linked to multiple neuro-developmental disorders, for which neonatal neuroimaging may allow earlier diagnosis and intervention. MRI is often considered the most sensitive imaging modality to white matter changes, while neurosonogram (NS) remains the clinical staple. This study assesses the correlation between MRI and US measurements of the neonatal CC using a protocol derived from established methodologies. Read More

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http://www.nature.com/articles/s41390-019-0386-8
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http://dx.doi.org/10.1038/s41390-019-0386-8DOI Listing
April 2019
3 Reads

Pediatric immunothrombosis-Understudied… but what potential!

Authors:
Christian C Yost

Pediatr Res 2019 Apr 9. Epub 2019 Apr 9.

Department of Pediatrics/Neonatology, University of Utah, Salt Lake City, Utah, USA.

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http://www.nature.com/articles/s41390-019-0389-5
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http://dx.doi.org/10.1038/s41390-019-0389-5DOI Listing
April 2019
2 Reads

Join World Birth Defects Day.

Pediatr Res 2019 Apr 9. Epub 2019 Apr 9.

Alessandra Lisi International Centre on Birth Defects and Prematurity-ICBD, Rome, Italy.

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http://dx.doi.org/10.1038/s41390-019-0392-xDOI Listing
April 2019
1 Read
2.314 Impact Factor

Enhanced early prediction of clinically relevant neonatal hyperbilirubinemia with machine learning.

Pediatr Res 2019 Mar 31. Epub 2019 Mar 31.

Adaptive Systems and Medical Data Science, Department of Mathematics and Computer Science, University of Basel, Basel, Switzerland.

Background: Machine learning models may enhance the early detection of clinically relevant hyperbilirubinemia based on patient information available in every hospital.

Methods: We conducted a longitudinal study on preterm and term born neonates with serial measurements of total serum bilirubin in the first two weeks of life. An ensemble, that combines a logistic regression with a random forest classifier, was trained to discriminate between the two classes phototherapy treatment vs. Read More

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http://dx.doi.org/10.1038/s41390-019-0384-xDOI Listing
March 2019
2.314 Impact Factor

Ontogeny of cytokine responses to PHA from birth to adulthood.

Pediatr Res 2019 Mar 31. Epub 2019 Mar 31.

Laboratory of Immunology, Robert-Debré Hospital, Assistance Publique-Hôpitaux de Paris AP-HP, 75019, Paris, France.

Background: Altered production of cytokines is believed to contribute to early childhood susceptibility to infection. The aim of this study was to get further insight into the developmental patterns of cytokine responses from birth to adulthood.

Methods: The expression levels of 13 cytokines were compared in the supernatants of phytohemaggluttinin (PHA)-stimulated whole blood from healthy neonates (cord blood, n = 8), infants ( < 1-year-old, n = 20), and school-aged children (3-15 y; n = 20). Read More

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http://dx.doi.org/10.1038/s41390-019-0383-yDOI Listing
March 2019
2.314 Impact Factor

June EIC biocommentary.

Pediatr Res 2019 Mar 25. Epub 2019 Mar 25.

Children's National Health System - Neonatology, 111 Michigan Ave. NW, Washington, DC, 20010, USA.

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http://dx.doi.org/10.1038/s41390-019-0380-1DOI Listing

Comparison of fetal growth by maternal prenatal acetaminophen use.

Pediatr Res 2019 Mar 25. Epub 2019 Mar 25.

Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.

Background: Equivocal findings exist regarding prenatal acetaminophen use and various adverse neonatal and childhood health outcomes, though with no data on fetal growth. We evaluated whether fetal growth differed by maternal acetaminophen use.

Methods: Racially diverse, healthy women with low-risk antenatal profiles from 12 US clinical centers were enrolled in a prospective cohort study and followed until delivery. Read More

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http://dx.doi.org/10.1038/s41390-019-0379-7DOI Listing

Commentary on "The point-of-care Bilistick method has very short turn-around-time and high accuracy at lower cut-off levels to predict laboratory-measured TSB."

Authors:
Carlo Dani

Pediatr Res 2019 Mar 22. Epub 2019 Mar 22.

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.

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http://dx.doi.org/10.1038/s41390-019-0378-8DOI Listing
March 2019
2 Reads

Correction: Maternal obesity and offspring cognition: the role of inflammation.

Pediatr Res 2019 Mar 22. Epub 2019 Mar 22.

Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Following publication of this article, the authors noted that the name of the last author was incorrectly displayed as 'Sen Sarbattama'. This authors name has now been corrected to 'Sarbattama Sen'. This has been corrected in both the PDF and HTML versions of the article. Read More

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http://dx.doi.org/10.1038/s41390-019-0375-yDOI Listing

Family reflections: MPS II.

Authors:
Jane Andrews

Pediatr Res 2019 Mar 20. Epub 2019 Mar 20.

, Washington, DC, USA.

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http://dx.doi.org/10.1038/s41390-019-0374-zDOI Listing

Family reflection: postnatal depression.

Authors:
Renee Knight

Pediatr Res 2019 Mar 20. Epub 2019 Mar 20.

Perinatal Anxiety and Depression Australia (PANDA) community champion, Melbourne, Australia.

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http://dx.doi.org/10.1038/s41390-019-0377-9DOI Listing
March 2019
1 Read

CD82 supports survival of childhood acute myeloid leukemia cells via activation of Wnt/β-catenin signaling pathway.

Pediatr Res 2019 Mar 12. Epub 2019 Mar 12.

Department of Pediatrics, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.

Background: Stem cell marker CD82 plays a vital role in the oncogenesis and progression of acute myelogenous leukemia (AML), especially in sharing properties of leukemia stem cells (LSCs). The Wnt/β-catenin pathway is required for the development of LSCs in AML. The present study aimed to validate whether CD82 supports the survival of LSCs in pediatric AML via activation of Wnt/β-catenin signaling pathway. Read More

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http://www.nature.com/articles/s41390-019-0370-3
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March 2019
4 Reads

Differences in patient characteristics and care practices between two trials of therapeutic hypothermia.

Pediatr Res 2019 Mar 12. Epub 2019 Mar 12.

Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.

Background: The Induced Hypothermia (IH) and Optimizing Cooling (OC) trials for hypoxic-ischemic encephalopathy (HIE) had similar inclusion criteria. The rate of death/moderate-severe disability differed for the subgroups treated with therapeutic hypothermia (TH) at 33.5 °C for 72 h (44% vs. Read More

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http://dx.doi.org/10.1038/s41390-019-0371-2DOI Listing
March 2019
1 Read

Co-occurrence of infantile hypertrophic pyloric stenosis and congenital heart defects: a nationwide cohort study.

Pediatr Res 2019 Mar 12. Epub 2019 Mar 12.

Department of Epidemiology Research, Statens Serum Institut, 5 Artillerivej, DK-2300, Copenhagen S, Denmark.

Background: Recent studies suggest that infantile hypertrophic pyloric stenosis (IHPS) and congenital heart defects (CHDs) may share some genetic risk factors, but little is known about the co-occurrence of the two conditions in patients.

Methods: Our study cohort included 2,212,756 persons born in Denmark 1977-2013. We identified patients with IHPS and CHD in the National Patient Register. Read More

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http://dx.doi.org/10.1038/s41390-019-0369-9DOI Listing

Screening for postpartum depression: obligation and opportunity for pediatricians to improve the lives of children.

Pediatr Res 2019 Mar 12. Epub 2019 Mar 12.

Department of Pediatrrics, Indiana University, Indianapolis, IN, USA.

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http://dx.doi.org/10.1038/s41390-019-0373-0DOI Listing
March 2019
1 Read

Why, when, and how to give surfactant.

Authors:
Alan H Jobe

Pediatr Res 2019 Mar 12. Epub 2019 Mar 12.

Division of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1038/s41390-019-0372-1DOI Listing

Umbilical cord blood versus mesenchymal stem cells for inflammation-induced preterm brain injury in fetal sheep.

Pediatr Res 2019 Mar 11. Epub 2019 Mar 11.

The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC, Australia.

Background: Chorioamnionitis and fetal inflammation are principal causes of neuropathology detected after birth, particularly in very preterm infants. Preclinical studies show that umbilical cord blood (UCB) cells are neuroprotective, but it is uncertain if allogeneic UCB cells are a feasible early intervention for preterm infants. In contrast, mesenchymal stem cells (MSCs) are more readily accessible and show strong anti-inflammatory benefits. Read More

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http://dx.doi.org/10.1038/s41390-019-0366-zDOI Listing

Human milk as "chrononutrition": implications for child health and development.

Pediatr Res 2019 Mar 11. Epub 2019 Mar 11.

Center for Excellence in Biopsychosocial Approaches to Health, Chapman University, Orange, CA, USA.

Human biology follows recurring daily rhythms that are governed by circadian cues in the environment. Here we show that human milk is a powerful form of "chrononutrition," formulated to communicate time-of-day information to infants. However, 85% of breastfed infants in the US consume some milk that does not come directly from the breast but is pumped and stored in advance of feeding. Read More

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http://dx.doi.org/10.1038/s41390-019-0368-xDOI Listing
March 2019
5 Reads

LED-phototherapy does not induce oxidative DNA damage in hyperbilirubinemic Gunn rats.

Pediatr Res 2019 Mar 9. Epub 2019 Mar 9.

Section of Molecular Metabolism and Nutrition, Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Background: Phototherapy (PT) is the standard treatment of neonatal unconjugated hyperbilirubinemia. Fluorescent tube (FT)-emitted PT light is known to induce oxidative DNA damage in neonates. Nowadays, however, FTs have largely been replaced by light-emitting diodes (LEDs) for delivering PT. Read More

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http://dx.doi.org/10.1038/s41390-019-0367-yDOI Listing
March 2019
3 Reads

Differential effects of Clostridium difficile toxins on ion secretion and cell integrity in human intestinal cells.

Pediatr Res 2019 Mar 9. Epub 2019 Mar 9.

Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples, Italy.

Background: Toxin A (TcdA), toxin B (TcdB), and binary toxin (CDT) produced by Clostridium difficile (CD) are thought to play a key role in inducing diarrhea. The aim of this study was to investigate the individual and combined roles of CD toxins in inducing enterotoxic and cytotoxic effect.

Methods: Ion secretion and epithelial damage were evaluated in the Ussing chambers as measure of enterotoxic or cytotoxic effect, respectively, in human-derived intestinal cells. Read More

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http://dx.doi.org/10.1038/s41390-019-0365-0DOI Listing
March 2019
2 Reads

Origins of neonatal leptin deficiency in preterm infants.

Pediatr Res 2019 Mar 7. Epub 2019 Mar 7.

Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.

Background: Cord blood leptin increases with advancing gestation. Preterm delivery leads to premature separation from the maternal and placental leptin source predisposing infants to postnatal leptin deficiency, but this has not been fully described.

Method: Blood leptin levels were measured for infants born before 33 weeks gestation daily for the first 2 days, then weekly until 36 weeks postmenstrual age (PMA). Read More

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http://dx.doi.org/10.1038/s41390-019-0359-yDOI Listing
March 2019
3 Reads

Correction: MIF inhibition enhances pulmonary angiogenesis and lung development in congenital diaphragmatic hernia.

Pediatr Res 2019 Apr;85(5):735

Division of Neonatal-Perinatal Medicine, Cohen Children's Medical Center, and Lilling Family Neonatal Research Laboratory, Feinstein Institute for Medical Research, Manhasset, NY, USA.

In the original version of this article, the name of the author "Kamesh Ayasolla" was incorrectly given as "Kamesh Ayyasola". This has now been corrected to "Kamesh Ayasolla" in both the PDF and HTML versions of the article. Read More

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http://dx.doi.org/10.1038/s41390-019-0362-3DOI Listing
April 2019
1 Read

Poverty and chronic illness: why safety net programs matter.

Pediatr Res 2019 Mar 6. Epub 2019 Mar 6.

Department of Pediatrics, Division of Pediatric Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1038/s41390-019-0363-2DOI Listing

Invited Commentary on 'Prospective associations between television in the preschool bedroom and later bio-psycho-social risks'.

Authors:
Aric Sigman

Pediatr Res 2019 Mar 5. Epub 2019 Mar 5.

All-Party Parliamentary Group on a Fit and Healthy Childhood, London, UK.

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http://dx.doi.org/10.1038/s41390-019-0357-0DOI Listing

Prolonged early antimicrobials in ELBWs: too much for too little.

Authors:
James L Wynn

Pediatr Res 2019 Mar 5. Epub 2019 Mar 5.

Department of Pediatrics, Division of Neonatology, University of Florida, 1600 SW Archer Road, PO Box 100296, Gainesville, FL, USA.

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http://dx.doi.org/10.1038/s41390-019-0360-5DOI Listing

Family reflections: Hirschsprung disease.

Pediatr Res 2019 Mar 5. Epub 2019 Mar 5.

, Winnipeg, Canada.

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http://dx.doi.org/10.1038/s41390-019-0361-4DOI Listing

Commentary on "Oxygen desaturations in the early neonatal period predict development of bronchopulmonary dysplasia" by Fairchild et al.

Authors:
Natalie L Davis

Pediatr Res 2019 Mar 5. Epub 2019 Mar 5.

Division of Neonatology, Department of Pediatrics, University of Maryland School of Medicine, 110 S. Paca Street, 8th Floor, Baltimore, MD, 21201, USA.

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http://dx.doi.org/10.1038/s41390-019-0358-zDOI Listing

Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.

Pediatr Res 2019 Mar 1. Epub 2019 Mar 1.

Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Background: The miR-214 has been reported to be associated with various diseases, but its involvement in the pathophysiology of Hirschsprung disease (HSCR) is almost completely unexplored.

Methods: In our study, we conducted a series of experiments to unravel the biological role of miR-214 in the pathophysiology of HSCR. qRT-PCR and western blotting were utilized to investigate the relative expression levels of miR-214, mRNAs, and proteins of related genes in colon tissues from 20 controls without HSCR and 24 patients with HSCR. Read More

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http://dx.doi.org/10.1038/s41390-019-0324-9DOI Listing

Correction: The effect of light wavelength on in vitro bilirubin photodegradation and photoisomer production.

Pediatr Res 2019 Feb 27. Epub 2019 Feb 27.

Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Room S214, Stanford, CA, 94305, USA.

Following publication of this article, the authors noticed that an incorrect affiliation was assigned to the author "Lucie Muchová". The original article has now been updated so that the author "Lucie Muchová" is associated with the "Institute of Medical Biochemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University, Kateřinská 32, 120 00 Prague, Czech Republic". This has been corrected in both the PDF and HTML versions of the article. Read More

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http://dx.doi.org/10.1038/s41390-019-0356-1DOI Listing
February 2019