4,923 results match your criteria Pediatric Clinics of North America[Journal]


Dedication to Julie Rich Ingelfinger.

Authors:
James C Chan

Pediatr Clin North Am 2019 Feb;66(1):xxi-xxiii

Tufts University, The Barbara Bush Children's Hospital, 22 Bramhall Street, Portland, ME 04102-3175, USA.

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http://dx.doi.org/10.1016/j.pcl.2018.10.004DOI Listing
February 2019

Dealing with the Challenges of the Good Fortune of an Abundance of New Knowledge.

Authors:
Bonita F Stanton

Pediatr Clin North Am 2019 Feb;66(1):xvii-xviii

Hackensack Meridian School of Medicine at Seton Hall University, 340 Kingsland Street, Building 123, Nutley, NJ 07110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pcl.2018.10.003DOI Listing
February 2019

Clinical Disorders of the Kidney.

Authors:
James C Chan

Pediatr Clin North Am 2019 Feb;66(1):xix-xx

Tufts University The Barbara Bush Children's Hospital Maine Medical Center, 22 Bramhall Street, Portland, ME 04102-3175, USA.

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http://dx.doi.org/10.1016/j.pcl.2018.10.002DOI Listing
February 2019

Lupus Nephritis.

Pediatr Clin North Am 2019 Feb;66(1):87-99

Department of Pathology and Immunology, Baylor College of Medicine, Texas Children's Hospital, 6621 Fannin Street, Suite AB195, Houston, TX 77030, USA.

Childhood-onset systemic lupus erythematosus (SLE) is a subset of SLE with an onset before 18 years of age. Patients with early onset SLE tend to have a greater genetic component to their disease cause, more multisystemic involvement, and a more severe disease course, which includes greater risks for developing nephritis and end-stage kidney disease. Five- and 10-year mortality is lower than in adult-onset SLE. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.08.007DOI Listing
February 2019
6 Reads

Nephrotic Syndrome.

Pediatr Clin North Am 2019 Feb;66(1):73-85

Division of Pediatric Nephrology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 2015 Uppergate Drive Northeast, Atlanta, GA 30322-1015, USA.

Nephrotic syndrome is characterized by edema, proteinuria, hypoalbuminemia, and hyperlipidemia. Minimal change disease, the most common cause in childhood, generally responds to corticosteroids, although most patients experience disease relapses. Focal segmental glomerulosclerosis is usually resistant to corticosteroids and carries a significant risk of kidney failure, necessitating renal transplantation. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.08.006DOI Listing
February 2019
1 Read

Infection-Related Glomerulonephritis.

Pediatr Clin North Am 2019 Feb;66(1):59-72

Division of Nephrology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.

Acute postinfectious glomerulonephritis or infection-related glomerulonephritis has been associated with several viral or bacterial infections. Group A beta-hemolytic streptococcal infection is the prototypical cause of postinfectious glomerulonephritis and the main focus of this discussion. The clinical spectrum can vary widely, from asymptomatic microscopic hematuria incidentally detected on routine urinalysis to rapidly progressive glomerulonephritis with acute kidney injury requiring emergent dialysis. Read More

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February 2019
3 Reads

Pediatric Hypertension: Diagnosis, Evaluation, and Treatment.

Pediatr Clin North Am 2019 Feb;66(1):45-57

Division of Pediatric Nephrology and Hypertension, McGovern Medical School at the University of Texas Health Science Center, 6431 Fannin Street, MSB 3-121, Houston, TX 77030, USA. Electronic address:

The etiology of hypertension in children and adolescents is varied; however, the prevalence of pediatric primary hypertension is increasing. Early identification and appropriate management of hypertension in children and adolescents is important to prevent the development of hypertensive end organ disease. The 2017 American Academy of Pediatrics Clinical Practice Guidelines for the Screening and Management of High Blood Pressure in Children and Adolescents provide a comprehensive reference for evaluation and management of hypertension in this age group and should be used when assessing patients with elevated blood pressure and hypertension. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.09.001DOI Listing
February 2019
2 Reads

Childhood Obesity and the Metabolic Syndrome.

Pediatr Clin North Am 2019 Feb;66(1):31-43

Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 7022, Cincinnati, OH 45229, USA.

Obesity is a leading cause of chronic kidney disease. Children with severe obesity have an increased prevalence of early kidney abnormalities and are at high risk to develop kidney failure in adulthood. The pathophysiology of obesity-related kidney disease is incompletely understood, although the postulated mechanisms of kidney injury include hyperfiltration, adipokine dysregulation, and lipotoxic injury. Read More

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February 2019
5 Reads

Long-Term Outcomes of Kidney Transplantation in Children.

Pediatr Clin North Am 2019 Feb;66(1):269-280

Division of Pediatric Nephrology, Emory University School of Medicine, Children's Pediatric Institute, 2015 Uppergate Drive NE, 5th Floor, Atlanta, GA 30322, USA.

Kidney transplantation is the preferred treatment for end-stage renal disease (ESRD) in children and confers improved survival, skeletal growth, heath-related quality of life, and neuropsychological development compared with dialysis. Kidney transplantation in children with ESRD results in 10-year patient survival exceeding 90%. Therefore, the long-term management of these patients is focused on maintaining quality of life and minimizing long-term side effects of immunosuppression. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251502PMC
February 2019
4 Reads

Chronic Kidney Disease and Dietary Measures to Improve Outcomes.

Authors:
Oleh M Akchurin

Pediatr Clin North Am 2019 Feb;66(1):247-267

Weill Cornell Medical College (Pediatric Nephrology), 525 E 68th Street, Box 176, New York, NY 10065, USA. Electronic address:

Chronic kidney disease is an ongoing deterioration of renal function that often progresses to end-stage renal disease. Management goals in children include slowing disease progression, prevention and treatment of complications, and optimizing growth, development, and quality of life. Nutritional management is critically important to achieve these goals. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.09.007DOI Listing
February 2019
6 Reads

Hemolytic Uremic Syndrome.

Pediatr Clin North Am 2019 Feb;66(1):235-246

Departments of Pediatrics & Medicine, University of Colorado School of Medicine, 12631 E. 17th Avenue, Aurora, CO 80045, USA. Electronic address:

Hemolytic uremic syndrome (HUS) is the clinical triad of thrombocytopenia, anemia, and acute kidney injury. Classically associated with enterocolitis from Shiga toxin-producing Escherichia coli, HUS is also associated with Streptococcus pneumoniae infections; genetic dysregulation of the alternative complement pathway or coagulation cascade; and, rarely, a hereditary disorder of cobalamin C metabolism. These share a common final pathway of a prothrombotic and proinflammatory state on the endothelial cell surface, with fibrin and platelet deposition. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.09.011DOI Listing
February 2019
7 Reads

Nephrogenic Diabetes Insipidus.

Pediatr Clin North Am 2019 Feb;66(1):227-234

Department of Pediatric Nephrology, Columbia University Medical Center, 3959 Broadway, CHN 1115, New York, NY 10032, USA. Electronic address:

Nephrogenic diabetes insipidus (NDI) results from the inability of the late distal tubules and collecting ducts to respond to vasopressin. The lack of ability to concentrate urine results in polyuria and polydipsia. Primary and acquired forms of NDI exist in children. Read More

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February 2019
7 Reads

Syndrome of Inappropriate Antidiuresis.

Authors:
Michael L Moritz

Pediatr Clin North Am 2019 Feb;66(1):209-226

Pediatric Nephrology, Pediatric Dialysis, Division of Nephrology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA. Electronic address:

The syndrome of inappropriate antidiuresis (SIAD) is a common cause of hyponatremia in hospitalized children. SIAD refers to euvolemic hyponatremia due to nonphysiologic stimuli for arginine vasopressin production in the absence of renal or endocrine dysfunction. SIAD can be broadly classified as a result of tumors, pulmonary or central nervous system disorders, medications, or other causes such as infection, inflammation, and the postoperative state. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.09.005DOI Listing
February 2019
1 Read

Hypophosphatemic Rickets.

Pediatr Clin North Am 2019 Feb;66(1):179-207

The Research Institute of the McGill University Health Centre, 1001 Boulevard Décarie, Room EM1.2232, Montreal, Quebec H4A3J1, Canada.

Hypophosphatemic rickets, mostly of the X-linked dominant form caused by pathogenic variants of the PHEX gene, poses therapeutic challenges with consequences for growth and bone development and portends a high risk of fractions and poor bone healing, dental problems and nephrolithiasis/nephrocalcinosis. Conventional treatment consists of PO4 supplements and calcitriol requiring monitoring for treatment-emergent adverse effects. FGF23 measurement, where available, has implications for the differential diagnosis of hypophosphatemia syndromes and, potentially, treatment monitoring. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.09.004DOI Listing
February 2019
1 Read
2.198 Impact Factor

Update on Dent Disease.

Pediatr Clin North Am 2019 Feb;66(1):169-178

Division of Nephrology, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA. Electronic address:

Dent disease is an X-linked form of chronic kidney disease characterized by hypercalciuria, low molecular weight proteinuria, nephrocalcinosis, and proximal tubular dysfunction. Clinical presentation is highly variable. Male patients may present with early-onset rickets, recurrent nephrolithiasis, or insidiously with asymptomatic proteinuria or chronic kidney disease. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.09.003DOI Listing
February 2019
3 Reads

Fanconi Syndrome.

Authors:
John W Foreman

Pediatr Clin North Am 2019 Feb;66(1):159-167

Department of Pediatrics, Duke University School of Medicine, Erwin Road, Durham, NC 27710, USA. Electronic address:

Fanconi syndrome, also known as the DeToni, Debré, Fanconi syndrome is a global dysfunction of the proximal tubule characterized by glucosuria, phosphaturia, generalized aminoaciduria, and type II renal tubular acidosis. Often there is hypokalemia, sodium wasting, and dehydration. In children, it typically is caused by inborn errors of metabolism, principally cystinosis. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.09.002DOI Listing
February 2019
1 Read

Approach to the Child with Hematuria.

Pediatr Clin North Am 2019 Feb;66(1):15-30

Pediatric Nephrology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, 3415 Bainbridge Avenue, Bronx, NY 10467, USA. Electronic address:

The causes of macroscopic and microscopic hematuria overlap; both are often caused by urinary tract infections or urethral/bladder irritation. Coexistent hypertension and proteinuria should prompt investigation for glomerular disease. The most common glomerulonephritis in children is postinfectious glomerulonephritis. Read More

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February 2019
2 Reads

Renal Tubular Acidosis.

Pediatr Clin North Am 2019 Feb;66(1):135-157

Division of Nephrology, Department of Pediatrics, The Montreal Children's Hospital, McGill University Health Centre, Room B RC.6651, Montreal, Quebec H4A 3J1, Canada; Al Jalila Children's Hospital, Al Jadaf PO Box 7662, Dubai, UAE. Electronic address:

Renal tubular acidosis should be suspected in poorly thriving young children with hyperchloremic and hypokalemic normal anion gap metabolic acidosis, with/without syndromic features. Further workup is needed to determine the type of renal tubular acidosis and the presumed etiopathogenesis, which informs treatment choices and prognosis. The risk of nephrolithiasis and calcinosis is linked to the presence (proximal renal tubular acidosis, negligible stone risk) or absence (distal renal tubular acidosis, high stone risk) of urine citrate excretion. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.08.011DOI Listing
February 2019
6 Reads
2.198 Impact Factor

Bartter Syndrome and Gitelman Syndrome.

Pediatr Clin North Am 2019 Feb;66(1):121-134

Department of Pediatrics, Inova Children's Hospital, 3300 Gallows Road, Falls Church, VA 22042, USA; Division of Nephrology and Hypertension, Pediatric Specialists of Virginia, 3023 Hamaker Court, Suite 600, Fairfax, VA 22031, USA; Virginia Commonwealth School of Medicine, Richmond, VA, USA. Electronic address:

Bartter and Gitelman syndromes are conditions characterized by renal salt-wasting. Clinical presentations range from severe antenatal disease to asymptomatic with incidental diagnosis. Hypokalemic hypochloremic metabolic alkalosis is the common feature. Read More

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February 2019
5 Reads

Tubulointerstitial Nephritis.

Pediatr Clin North Am 2019 Feb;66(1):111-119

Department of Pediatrics, Division of Nephrology, Johns Hopkins University School of Medicine, 200 North Wolfe Street, Room 3055, Baltimore, MD 21287, USA.

Tubulointerstitial nephritis (TIN) is a cause of acute kidney injury in children characterized histologically by an inflammatory cell infiltrate in the kidney interstitium. The most common causes of TIN in children include medications, infections, inflammatory disorders, and genetic conditions. TIN typically presents with nonoliguric acute kidney injury and may be associated with systemic symptoms, including fever, rash, and eosinophilia. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.08.009DOI Listing
February 2019
9 Reads

Immunoglobulin A Nephropathy and Immunoglobulin A Vasculitis.

Pediatr Clin North Am 2019 Feb;66(1):101-110

Department of Pediatrics, Medical University of South Carolina, 96 Jonathan Lucas Street, 428 CSB, MSC 608, Charleston, SC 29425, USA. Electronic address:

Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are common glomerulopathies in the pediatric population that deserve special attention. In some cases the primary care provider can follow the patient but others need more intensive management. Delaying this treatment can lead to worse morbidity. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.08.008DOI Listing
February 2019
1 Read

Urinary Tract Infections.

Pediatr Clin North Am 2019 Feb;66(1):1-13

Nephrology Section, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA; Department of Pediatrics, Ohio State University School of Medicine, 700 Children's Drive, Columbus, OH 43210, USA; Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, 700 Children's Drive, W308, Columbus, OH 43205, USA. Electronic address:

Urinary tract infection (UTI) is the second most common bacterial infection in children and is considered a public health threat given the mounting rates of antibiotic-resistance among uropathogens. This article highlights recent encouraging developments in UTI research. Further work is necessary to translate the discoveries into accessible, cost-effective technologies that will aid clinicians in real-time decision-making. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.08.002DOI Listing
February 2019
1 Read

Pediatric Emergency Medicine.

Authors:
Prashant Mahajan

Pediatr Clin North Am 2018 Dec;65(6):xvii-xix

Department of Emergency Medicine, Pediatric Emergency Medicine, CS Mott Children's Hospital of Michigan, 1540 East Hospital Drive, Room 2-737, SPC 4260, Ann Arbor, MI 48109-4260, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pcl.2018.09.009DOI Listing
December 2018

The Changing Role of Emergency Medicine.

Authors:
Bonita F Stanton

Pediatr Clin North Am 2018 Dec;65(6):xv-xvi

Hackensack Meridian School of Medicine at Seton Hall University, 340 Kingsland Street, Building 123, Nutley, NJ 07110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pcl.2018.09.010DOI Listing
December 2018

Quality Improvement Methodologies: Principles and Applications in the Pediatric Emergency Department.

Pediatr Clin North Am 2018 Dec;65(6):1283-1296

Department of Pediatrics, Division of Emergency Medicine and Emergency Department, Seattle Children's Hospital, University of Washington School of Medicine, MB.7.520, PO Box 5371, Seattle, WA 98145-5005, USA.

The origins of quality improvement in health care trace back to industry. Lessons learned from the "flow production" system of the Ford Model-T assembly line in Michigan and the Toyota Production System led to direct applications of Lean and Six Sigma to improve health care systems. Emergency medicine is well suited as a testing and proving ground for quality improvement methodologies because of high patient volume and rapid turnover. Read More

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December 2018
3 Reads

Quality Improvement and Safety in Pediatric Emergency Medicine.

Pediatr Clin North Am 2018 Dec;65(6):1269-1281

Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19146, USA.

Pediatric emergency medicine quality work continues to focus on the National Academies of Sciences, Engineering, and Medicine's 6 domains of quality, with a need for specific emphasis on equity and patient centeredness. Adopting the principles of high-reliability organizations, pediatric emergency departments should become increasing transparent with benchmarking and collaboration across institutions in order to develop an infrastructure for quality and safety to improve the care of pediatric patients in the emergency department. Read More

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December 2018

Pediatric Urgent Care-New and Evolving Paradigms of Acute Care.

Pediatr Clin North Am 2018 Dec;65(6):1257-1268

PM Pediatrics Management Group, One Hollow Lane, Suite 301, Lake Success, NY 11042, USA.

Parents of pediatric patients seek appropriate high-quality care in a timely, cost-effective, and convenient manner. Pediatric urgent care offers a new and evolving delivery model that serves a growing demand by complementing services provided by the medical home and by pediatric emergency departments. Pediatric urgent care services are used by both nonprofit and for-profit sectors and include hospital and satellite clinics, free-standing clinics, retail-based clinics, and telemedicine services. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.07.014DOI Listing
December 2018

The Impact of the Evolving Health Care System on Pediatric Emergency Care.

Authors:
Lalit Bajaj

Pediatr Clin North Am 2018 Dec;65(6):1247-1256

Clinical Effectiveness, University of Colorado School of Medicine, Children's Hospital Colorado, 13123 East 16th Avenue B400, Aurora, CO 80045, USA. Electronic address:

This article discusses the implications of health care reform on the pediatric emergency department (ED). The author briefly discusses the health care costs and outcomes in the United States in comparison to other developed nations. The article discusses the impact of the Affordable Care Act and insurance expansion on the pediatric ED. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.07.007DOI Listing
December 2018
1 Read

Recent Advances in Technology and Its Applications to Pediatric Emergency Care.

Pediatr Clin North Am 2018 Dec;65(6):1229-1246

Department of Biomedical and Health Informatics, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia, Roberts Center, 2716 South Street, 15th Floor, Philadelphia, PA 19146, USA.

Advances in technology are continuously transforming medical care, including pediatric emergency medicine. The increasing adoption of point-of-care ultrasound examination can improve timely diagnoses without radiation and aids the performance of common procedures. The recent dramatic increase in electronic health record adoption offers an opportunity for enhanced clinical decision-making support. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.07.013DOI Listing
December 2018
1 Read

Advances in Medical Education and Implications for the Pediatric Emergency Department.

Pediatr Clin North Am 2018 Dec;65(6):1221-1227

Departments of Emergency Medicine and Pediatrics, University of Michigan, 1500 East Medical Center Drive, SPC 5303, Taubman Center, B1 - 354, Ann Arbor, MI 48109-5303, USA.

The learning environment of the pediatric emergency department is composed of many layers that provide opportunity for intervention to improve the education of residents and medical students. Creating an intentional plan of targeted interventions at the levels of learner, teacher, and department can create a culture where education is highly regarded. This article briefly defines the learning environment and explores strategies for improving clinical teaching at these various levels through improved teacher-learner relationships, entrustment, and the implementation of teaching strategies that can be easily incorporated into the busy and time-stretched work of the pediatric emergency department. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.07.008DOI Listing
December 2018

Pediatric Disaster Preparedness.

Pediatr Clin North Am 2018 Dec;65(6):1205-1220

Department of Emergency Medicine, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

Children can be victims of mass casualty or illness, but their needs, with respect to their care and recovery are substantially different from adults. Emergency or urgent care physicians must be prepared to evaluate and manage child victims presenting to their facility in numbers or acuity that could significantly overwhelm normal operations. This article presents the general approach to pediatric disaster preparation in the United States, the expectations of emergency department providers, and different methods of disaster triage, and introduces the most likely types of mass illness (some of which are bioweapons or chemical agents) and their management. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.07.015DOI Listing
December 2018

Indications and Interpretation of Common Laboratory Assays in the Emergency Department.

Authors:
Andrea T Cruz

Pediatr Clin North Am 2018 Dec;65(6):1191-1204

Department of Pediatrics, Sections of Emergency Medicine and Infectious Diseases, Baylor College of Medicine, 6621 Fannin Street, Suite A2210, Houston, TX 77030, USA. Electronic address:

Laboratory assays are commonly used to help clinicians more accurately gauge the risk a child has for a certain condition. This article reviews commonly obtained laboratory tests (complete blood cell counts, metabolic panels, blood gases, and urine assays) and discusses the data supporting obtaining these tests and reasons for spuriously positive or negative results. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.07.005DOI Listing
December 2018

Management of Adult Patients in the Pediatric Emergency Department.

Pediatr Clin North Am 2018 Dec;65(6):1167-1190

Division of Emergency Medicine, The Ohio State University, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA. Electronic address:

Adult patients often present to the pediatric emergency department (ED) for treatment of a wide variety of diseases. However, pediatric emergency medicine physicians are primarily trained to provide specialized care for children. Studies have shown that the number of adult patients presenting to pediatric EDs has increased significantly since the introduction of the Emergency Medicine Transfer and Active Labor Act in 1986. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.07.016DOI Listing
December 2018

Recent Advances in Pediatric Concussion and Mild Traumatic Brain Injury.

Pediatr Clin North Am 2018 Dec;65(6):1151-1166

Department of Emergency Medicine, Children's Emergency Services, Michigan Medicine, North Campus Research Complex, University of Michigan Injury Center, 2800 Plymouth Road, Suite G080, NCRC Building 10, Ann Arbor, MI 48105, USA. Electronic address:

Concussions after a head injury among children continues to be a substantial public health concern. An increasing number of concussions are being managed initially by primary care physicians. The diagnosis of concussion remains a clinical diagnosis despite the availability of ancillary tests such as computerized neuropsychological testing, advanced imaging, and blood biomarkers. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.07.006DOI Listing
December 2018
7 Reads

Child Abuse and Conditions That Mimic It.

Pediatr Clin North Am 2018 Dec;65(6):1135-1150

Department of Pediatrics and Communicable Diseases, University of Michigan, 1540 Hospital Drive, CW 2-737, Ann Arbor, MI 48109, USA; Department of Emergency Medicine, University of Michigan, 1540 Hospital Drive, CW 2-737, Ann Arbor, MI 48109, USA. Electronic address:

One percent to 2% of children in the United States are confirmed victims of child abuse, with many more likely affected. It can be difficult to diagnose, with often misleading medical histories, but acute care providers should be aware of its presenting warning signs and how to evaluate and document suspicious physical findings. Young children who cannot disclose are most vulnerable to forms of abuse with high morbidity and mortality, so it is important to keep it in the differential diagnosis and to be aware of and know how to rule out medical conditions that mimic abuse. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.07.009DOI Listing
December 2018

Critical Care in the Pediatric Emergency Department.

Pediatr Clin North Am 2018 Dec;65(6):1119-1134

Pediatric Critical Care Medicine, University of Michigan School of Medicine, 1500 East Medical Center Drive, SPC 5243, Ann Arbor, MI 48109-5243, USA. Electronic address:

In caring for critically ill children, recognition and management often begins in the pediatric emergency department. A seamless transition in care is needed to ensure appropriate care to the sickest of children. This review covers the management of critically ill children in the pediatric emergency department beyond the initial stabilization for conditions such as acute respiratory failure and pediatric acute respiratory distress syndrome, traumatic brain injury, status epilepticus, congenital heart disease, and metabolic emergencies. Read More

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December 2018
8 Reads

Recognition, Diagnostics, and Management of Pediatric Severe Sepsis and Septic Shock in the Emergency Department.

Authors:
Raina Paul

Pediatr Clin North Am 2018 Dec;65(6):1107-1118

Pediatric Emergency Department, Division of Emergency Medicine, Advocate Children's Hospital, 1700 Luther Lane, Park Ridge, IL 60068, USA. Electronic address:

Several new studies have emerged in recent years that have attempted to aid emergency department providers in recognizing and treating pediatric patients with severe sepsis and septic shock. National guidelines and supporting literature are unanimous in recommendations that early recognition and timely therapeutics are necessary for improved survival and decreased morbidity. The literature is less concrete in defining how emerging advances in the field can aid in time-sensitive care of these patients. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.07.012DOI Listing
December 2018

Diagnostic Decision-Making in the Emergency Department.

Pediatr Clin North Am 2018 Dec;65(6):1097-1105

Department of Emergency Medicine, CS Mott Children's Hospital of Michigan, 1540 East Hospital Drive, Room 2-737, SPC 4260, Ann Arbor, MI 48109-4260, USA.

Emergency medicine requires diagnosing unfamiliar patients with undifferentiated acute presentations. This requires hypothesis generation and questioning, examination, and testing. Balancing patient load, care across the severity spectrum, and frequent interruptions create time pressures that predispose humans to fast thinking or cognitive shortcuts, including cognitive biases. Read More

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December 2018
3 Reads
2.198 Impact Factor

Oral Health: A Critical Piece to Develop into a Healthy Adult.

Pediatr Clin North Am 2018 10;65(5):xvii-xix

Department of Pediatrics, UCSF School of Medicine, Zuckerberg San Francisco General Hospital, 1001 Potrero Avenue/MS6E37, San Francisco, CA 94110, USA; Department of Preventive and Restorative Dental Sciences, UCSF School of Dentistry, 505 Parnassus Avenue, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pcl.2018.07.001DOI Listing
October 2018

Teeth: Vital to Our Children's Health.

Authors:
Bonita F Stanton

Pediatr Clin North Am 2018 10;65(5):xv-xvi

Hackensack Meridian School of Medicine at Seton Hall University, 340 South Orange Street, Building 123, Nutley, NJ 07110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pcl.2018.07.002DOI Listing
October 2018

Orthodontics in Children and Impact of Malocclusion on Adolescents' Quality of Life.

Pediatr Clin North Am 2018 10;65(5):995-1006

Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Universidade Federal de Minas Gerais, Maranhão, Belo Horizonte, Minas Gerais 30150-331, Brazil. Electronic address:

Orthodontics is the dental specialty concerned with the position of teeth and the relationship between the maxilla and mandible. Much evidence regarding the characteristics of normal occlusion during childhood/adolescence, the timely referral of children/adolescents to orthodontic treatment, and the impact of orthodontic outcomes on individuals' physical, functioning, and psychosocial well-being exists in the literature. This body of evidence may be helpful for pediatricians and primary care physicians. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.05.008DOI Listing
October 2018

Oral Health for US Children with Special Health Care Needs.

Authors:
Donald L Chi

Pediatr Clin North Am 2018 10;65(5):981-993

Department of Oral Health Sciences, University of Washington, School of Dentistry, Box 357475, B509f Health Sciences Building, Seattle, WA 98195-7475, USA. Electronic address:

Children with special health care needs (CSHCN) are a vulnerable population subgroup, but little is known about their oral health, particularly regarding the prevalence and cause of tooth decay. This lack of knowledge is a barrier to progress in terms of developing evidence-based clinical interventions and policies aimed at promoting oral health in CSHCN. This article reviews the oral health literature pertaining to CSHCN, identifies critical knowledge gaps, highlights future research opportunities, and extends clinical recommendations to pediatric health care providers. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.05.007DOI Listing
October 2018

Oral Health Disparities in Children: A Canary in the Coalmine?

Pediatr Clin North Am 2018 10;65(5):965-979

Division of Oral Epidemiology and Dental Public Health, Center to Address Disparities in Children's Oral Health (Known As CAN DO), Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, Box #1361, San Francisco, CA 94143, USA.

Despite being largely preventable, oral diseases are still a major public health problem in child populations in many parts of the world. Increasingly, however, oral diseases disproportionately affect socially disadvantaged groups in society. It is unjust and unfair that children and families from disadvantaged backgrounds experience high levels of oral diseases. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.05.006DOI Listing
October 2018

The Burden and Management of Dental Caries in Older Children.

Pediatr Clin North Am 2018 10;65(5):955-963

Department of Pediatric Dentistry, School of Dentistry, The University of North Carolina, Brauer Hall #7450, Chapel Hill, NC 27599, USA. Electronic address:

Dental caries is endemic in children and adolescents and has significant morbidity. This complex and chronic disease has both genetic and environmental etiologic factors. In children the preponderance of caries affects tooth surfaces with pits and fissures despite these representing only a small portion of the tooth surfaces that are at risk. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.05.005DOI Listing
October 2018

Early Childhood Caries.

Authors:
Wan Kim Seow

Pediatr Clin North Am 2018 10;65(5):941-954

School of Dentistry, The University of Queensland, 288 Herston Road, Herston, Queensland 4006, Australia. Electronic address:

Early childhood caries (ECC) is a common childhood disease with highest prevalence found in poor, socially disadvantaged, and minority groups. The main risk factors for ECC are frequent sugar consumption, lack of tooth brushing, and enamel hypoplasia. Contributory factors include environmental and psychosocial stresses that modify caregiver behaviors. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.05.004DOI Listing
October 2018
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The Role of Fluoride in the Prevention of Tooth Decay.

Authors:
Howard Pollick

Pediatr Clin North Am 2018 10;65(5):923-940

Dental Public Health Residency Program, Division of Oral Epidemiology and Dental Public Health, Department of Preventive and Restorative Dental Sciences, School of Dentistry, University of California San Francisco, 707 Parnassus Avenue, Box 0758, San Francisco, CA 94143-0758, USA. Electronic address:

Although there are recommendations to prevent tooth decay by other means, this nonsystematic review finds that fluoride is the key to prevention and control of tooth decay. There are multiple fluoride modalities with effectiveness and safety of fluoride depending on dose and concentration. Prevention of tooth decay occurs at the individual level by fluoride use at home and with professional application and at the community level through fluoridation of water or salt. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.05.014DOI Listing
October 2018

Infant Oral Health.

Pediatr Clin North Am 2018 10;65(5):909-921

Department of Pediatrics, UW School of Medicine, Seattle Children's Hospital, UW Box 354920, Seattle, WA 98195, USA. Electronic address:

It may be easy to discount oral health in infancy because most infants are not born with teeth and only a few teeth erupt during the first year of life. Infancy, however, is a critical time for formation of habits. Positive habits, such as twice-daily brushing with fluoride toothpaste starting at first teeth eruption, provides topical fluoride, which is important for remineralization of the tooth and helps establish a lifelong healthy practice. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00313955183007
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http://dx.doi.org/10.1016/j.pcl.2018.05.016DOI Listing
October 2018
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A Developmental Approach to Pediatric Oral Health.

Pediatr Clin North Am 2018 10;65(5):885-907

Departments of Pediatric Dentistry and Academic Affairs, School of Dentistry, The University of North Carolina at Chapel Hill, 1611 Koury Oral Health Sciences Building, CB# 7450, Chapel Hill, NC 27599-7450, USA.

Orofacial growth and development is a complex process spanning the life course. This article provides an oral health overview in the context of overall growth, physical and social development from infancy through adolescence. It reviews oral health-specific developmental milestones during childhood (0-12 years) and adolescence (≥13 years). Read More

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http://dx.doi.org/10.1016/j.pcl.2018.05.003DOI Listing
October 2018

Pediatric Oral Health Policy: Its Genesis, Domains, and Impacts.

Pediatr Clin North Am 2018 10;65(5):1085-1096

Population Oral Health, Columbia University College of Dental Medicine, Columbia University Medical Center, 622 West 168th Street, PH7-311, Box 20, New York, NY 10032, USA; Children's Dental Health Project, 1020 19(th) Street NW, Suite 400, Washington, DC 20036. Electronic address:

Over recent years, pediatric oral health has become well established in the United States as an essential component of pediatric health policy as evidenced by the programs authorized and funded by Congress. These actions have improved access and utilization of dental care, engaged primary care pediatrics in oral health, and improved children's oral health outcomes. Nonetheless, there remains a host of authorized but unfunded approaches to addressing children's oral health through coverage, workforce, safety net, prevention, and surveillance. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.05.012DOI Listing
October 2018

Oral-Health-Related Quality of Life in Children and Adolescents.

Pediatr Clin North Am 2018 10;65(5):1073-1084

Cariology and Comprehensive Care, NYU College of Dentistry, New York University, 345 East 24th Street, New York, NY 10010, USA.

This article describes child oral health-related quality of life measures and provides some examples of their use in determining the effect of clinical interventions, such as dental treatment under general anesthesia, orthodontic treatment, and treatment of orofacial clefting. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.05.015DOI Listing
October 2018