704,243 results match your criteria Pediatric Allergy Immunology and Pulmonology[Journal]
Sportverletz Sportschaden 2018 Dec 11;32(4):251-259. Epub 2018 Dec 11.
Department of Sportsmedicine, Department of Orthopedic and Trauma Surgery, Klinikum Bamberg, Bamberg, Germany.
Rationale And Objectives: Pulley ruptures are the most common injuries in sport climbing. Ruptures of the A2 and A4 pulleys have been studied extensively, and ultrasound has proven to be a highly sensitive and specific tool for their diagnosis. However, the correct diagnosis of A3 pulley ruptures continues to be a challenge. Read More
Am J Perinatol 2018 Dec 11. Epub 2018 Dec 11.
Department of Pediatrics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Objective: To verify the prevalence of systemic arterial hypertension (SAH) and to identify possible early predictors of SAH at ages 2 and 4 years in very low birth weight (VLBW) infants.
Study Design: This is a prospective cohort study including inborn children with birth weight (BW) <1,500 g. Arterial blood pressure measurements were performed at 2 and 4 years. Read More
Klin Padiatr 2018 Dec 11. Epub 2018 Dec 11.
General University Hospital, Paediatric Rheumatology and Autoinflammatory Diseases Unit, Praha, Czech Republic.
Horm Res Paediatr 2018 Dec 11:1-10. Epub 2018 Dec 11.
Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University of Ulm, Ulm, Germany.
Background/aims: Mutations in the DAX1 gene cause X-linked adrenal hypoplasia congenita (AHC) classically associated with hypogonadotropic hypogonadism. Unexpectedly, precocious puberty (PP) has been reported in some cases, its mechanism remaining unclear.
Methods: We longitudinally studied a boy with AHC due to DAX1 gene mutation who developed peripheral PP at age 4. Read More
Child Abuse Negl 2018 Dec 8;88:201-211. Epub 2018 Dec 8.
Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, United States; The Ohio State University College of Medicine, Department of Pediatrics, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, United States. Electronic address:
Background: The majority of youth with problem sexualized behaviors (PSB) have substantiated experiences of abuse or exposures to violence (Silovsky & Niec, 2002). Little is known about specific abuse experiences that may differentiate youth with PSB from those without. Few studies have examined the types of abuse associated with post-traumatic stress symptomology. Read More
Biol Blood Marrow Transplant 2018 Dec 8. Epub 2018 Dec 8.
Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N Seattle, WA 98109. Electronic address:
Human rhinovirus lower respiratory tract infection is associated with mortality following hematopoietic cell transplantation; however, risk factors for lower respiratory tract infection are not well characterized. We sought to develop a risk score for progression to lower respiratory tract infection from upper respiratory tract infection in hematopoietic cell transplantation recipients. Risk factors for lower respiratory tract infection within 90 days were analyzed using Cox regression among hematopoietic cell transplantation recipients with rhinovirus upper respiratory tract infection between 1/2009-3/2016. Read More
Biol Blood Marrow Transplant 2018 Dec 8. Epub 2018 Dec 8.
Department of Hematology, Peking University People's Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Peking University, Beijing, China. Electronic address:
Background: The role of allogeneic hematopoietic stem cell transplantation (allo-HSCT), particularly haploidentical (haplo)-HSCT, in pediatric patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) in the tyrosine kinase inhibitor (TKI) era is unclear. This study aimed to identify prognostic factors and explore the role of haplo-HSCT in the treatment of Ph+ALL in the TKI era.
Methods: We analyzed clinical data of Ph+ALL patients aged 1-18 years who received imatinib added to intensive chemotherapy at the start of induction therapy. Read More
Eur J Pharm Sci 2018 Dec 8. Epub 2018 Dec 8.
Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address:
Background: Sirolimus is increasingly investigated as a new targeted therapy in pediatric populations. To date, population pharmacokinetic (PK) studies have identified several factors that explain in part the large between-patient variability in sirolimus PK. However, within-patient variability in sirolimus PK is not well documented. Read More
Cancer Cell 2018 Dec;34(6):996-1011.e8
Finsen Laboratory, Rigshospitalet, DK-2200, Copenhagen, Denmark; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, DK-2200, Copenhagen, Denmark; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69120 Heidelberg, Germany; Charité Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany. Electronic address:
Identifying the earliest somatic changes in prostate cancer can give important insights into tumor evolution and aids in stratifying high- from low-risk disease. We integrated whole genome, transcriptome and methylome analysis of early-onset prostate cancers (diagnosis ≤55 years). Characterization across 292 prostate cancer genomes revealed age-related genomic alterations and a clock-like enzymatic-driven mutational process contributing to the earliest mutations in prostate cancer patients. Read More
Cancer Cell 2018 Dec;34(6):922-938.e7
Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, USA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:
Drug resistance represents a major challenge to achieving durable responses to cancer therapeutics. Resistance mechanisms to epigenetically targeted drugs remain largely unexplored. We used bromodomain and extra-terminal domain (BET) inhibition in neuroblastoma as a prototype to model resistance to chromatin modulatory therapeutics. Read More
Cancer Cell 2018 Dec;34(6):869-871
Institute for Cancer Genetics, Columbia University, New York, NY 10032, USA; Department of Pediatrics, Columbia University Medical Center, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA; Department of Systems Biology, Columbia University, New York, NY 10032, USA. Electronic address:
Glucocorticoid resistance represents a major challenge in treating acute lymphoblastic leukemia. In this issue of Cancer Cell, Jing and colleagues show epigenetic deregulation of glucocorticoid-induced BIM activation in glucocorticoid-resistant leukemia cells, and restore glucocorticoid-receptor-induced BIM upregulation with DNA demethylating agents to effectively enhance glucocorticoid response. Read More
Neurosci Biobehav Rev 2018 Dec 8. Epub 2018 Dec 8.
Department of Pediatrics, Dalhousie University and the IWK Health Centre, Canada.
Regression in children with epilepsy may involve loss of cognitive abilities, failure to progress or a slowing of developmental trajectory. A few seizures do not lead to regression. Large numbers of seizures may be associated with regression but the cause is an important cofounder. Read More
J Oncol Pract 2018 Dec;14(12):e758-e769
Sarah Cannon Cancer Institutes at HCA Midwest Health, Overland Park, KS; University of Florida College of Medicine; Malcom Randall Veterans Affairs Medical Center, Gainesville; Florida Cancer Specialists, Deland, FL; University of Texas Southwestern Medical Center, Dallas, TX; and Cleveland Clinic Akron General, Akron, OH.
Purpose:: Meaningful connections are an important aspect of career satisfaction. The Hematology Oncology Women Physician Group (HOWPG) is a private Facebook (FB) group of 936 women who practice within the hematology/oncology (H/O) field. We hypothesized that HOWPG adds value to education, emotional wellness, and practice of oncology for its membership. Read More
Pediatr Blood Cancer 2018 Dec 10:e27569. Epub 2018 Dec 10.
Department of Pediatrics, Hematology/Oncology Section, Baylor College of Medicine, Houston, Texas.
Autoimmune cytopenias (AIC) post-hematopoietic stem cell transplant (HSCT) are rare but exceptionally challenging complication. We conducted a comprehensive literature review and identified a pooled incidence of post-HSCT autoimmune hemolytic anemia and/or immune thrombocytopenia of 2.66% (SE = 0. Read More
Dermatol Ther 2018 Dec 7:e12801. Epub 2018 Dec 7.
Department of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health.
The field of pediatric dermatology treatment has been rich in new developments. Several recent therapeutic advances in pediatric dermatology have been made. This review will focus on critical approach to the new treatments for several entities encountered in pediatric dermatology. Read More
Milbank Q 2018 Dec;96(4):706-754
Leonard and Madlyn Abramson Cancer Center of the University of Pennsylvania.
Policy Points Patients with low socioeconomic status (SES) experience poorer survival rates after diagnosis of breast cancer, even when enrolled in Medicare and Medicaid. Most of the difference in survival is due to more advanced cancer on presentation and the general poor health of lower SES patients, while only a very small fraction of the SES disparity is due to differences in cancer treatment. Even when comparing only low- versus not-low-SES whites (without confounding by race) the survival disparity between disparate white SES populations is very large and is associated with lower use of preventive care, despite having insurance. Read More
Neurogastroenterol Motil 2018 Dec 11:e13521. Epub 2018 Dec 11.
Center for Motility and Gastrointestinal Functional Disorders, Division of Gastroenterology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Background: We evaluated the changes in antroduodenal manometry (ADM) parameters and interpretation when the test is performed the day of catheter placement and the following day.
Methods: Catheter was placed endoscopically under anesthesia and recorded on day 1 and repeated on day 2. Study parameters including antrum and small bowel motility index (MI) during fasting, meal, postprandial, erythromycin (EES), and octreotide (OCT) challenge phases, the presence of the phase III of the migrating motor complex (MMC), visual postprandial response, and study interpretation were compared between both days. Read More
Xenotransplantation 2018 Dec 11:e12479. Epub 2018 Dec 11.
Department of Surgery and Department of Microbiology & Immunology, University of Michigan, Ann Arbor, Michigan.
The newborn infant with severe cardiac failure owed to congenital structural heart disease or cardiomyopathy poses a daunting therapeutic challenge. The ideal solution for both might be cardiac transplantation if availability of hearts was not limiting and if tolerance could be induced, obviating toxicity of immunosuppressive therapy. If one could safely and effectively exploit neonatal tolerance for successful xenotransplantation of the heart, the challenge of severe cardiac failure in the newborn infant might be met. Read More
Catheter Cardiovasc Interv 2018 Dec 7. Epub 2018 Dec 7.
Department of Pediatrics, Division of Cardiology, UCLA Mattel Children's Hospital, Los Angeles, California.
Objectives: To describe a multi-center experience of percutaneous transcatheter pulmonary valve replacement (TPVR) using the Edwards Sapien S3 Valve.
Background: Off-label use of the Sapien S3 valve can allow for TPVR in patients with congenital heart disease (CHD) and large diameter dysfunctional right ventricular outflow tract (RVOT). The initial experience at five centers with the SAPIEN S3 valve for TPVR is presented with a focus on procedural techniques, success, complications, and efficacy. Read More
Immunol Cell Biol 2018 Dec 11. Epub 2018 Dec 11.
Department of Pulmonary Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, Institute of Respiratory Diseases of Sun Yat, Sen University, Guangzhou, China.
Interleukin (IL)-37 has been described as a negative regulator of immune responses and is critical for asthma pathogenesis, but the mechanisms behind the protective role of IL-37 against allergic asthma are less well understood. We show here that IL-37 administered intranasally (i.n. Read More
J Paediatr Child Health 2018 Dec 8. Epub 2018 Dec 8.
Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
Aim: To evaluate the clinical and echocardiography modulators of treatment response in hypoxemic preterm infants exposed to inhaled nitric oxide (iNO).
Methods: In this multicentre retrospective study, clinical parameters, including oxygenation, ventilation and haemodynamics, were collected for preterm infants <36 weeks gestation before and 2 h after initiation of iNO for acute hypoxemia. Comprehensive echocardiography, performed near the time iNO initiation, was analysed by experts blind to the clinical course. Read More
Am J Med Genet A 2018 Nov 20;176(11):2522. Epub 2018 Sep 20.
Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, Washington.
Birth Defects Res 2018 Dec 10. Epub 2018 Dec 10.
Department of Linguistics, University of British Columbia, Vancouver, Canada.
The aerodigestive and communicative behaviors of anencephalic and hydranencephalic patients are assessed from literature sources and are compared with documented neural structures present in the brainstem, subcortical, and cortical regions of the brain. Much of the data analyzed corroborate previous neurological studies, which focus on central pattern generators and development in model organisms. However, findings suggest that further research is necessary to determine which components of these systems support these behaviors. Read More
Pediatr Obes 2018 Dec 10:e12486. Epub 2018 Dec 10.
Department of Pediatrics, School of Medical Sciences, University of Campinas, Campinas, Brazil.
Objective: In adults, hypothalamic gliosis has been documented using quantitative T2 neuroimaging, whereas functional magnetic resonance imaging (fMRI) has shown a defective hypothalamic response to nutrients. No studies have yet evaluated these hypothalamic abnormalities in children with obesity.
Methods: Children with obesity and lean controls underwent quantitative MRI measuring T2 relaxation time, along with continuous hypothalamic fMRI acquisition to evaluate early response to glucose ingestion. Read More
J Med Virol 2018 Dec 10. Epub 2018 Dec 10.
Division of Mental and Physical Health, Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Oslo, Norway.
Objectives: Direct genotyping of adenovirus or enterovirus from clinical material using polymerase chain reaction (PCR) followed by Sanger sequencing is often difficult due to the presence of multiple virus types in a sample, or due to varying efficacy of PCR amplifying the capsid gene on the background of foreign nucleic acids. Here we present a simple protocol for virus genotyping using massive parallel amplicon sequencing.
Methods: The protocol utilized a set of 16 tailed degenerate primers flanking the seventh hypervariable region of the adenovirus hexon gene and 9 tailed degenerate primers targeted to the proximal portion of the enterovirus VP1 gene. Read More
Pediatr Transplant 2018 Dec 7:e13334. Epub 2018 Dec 7.
Pediatric Nephrology at Children's Healthcare of Atlanta, Atlanta, Georgia.
Introduction: There are limited data to guide optimal treatment strategies for acute cellular rejection (ACR) based on Banff grade for pediatric kidney transplant recipients. This report reviews a large pediatric transplant center's experience with ACR.
Materials And Methods: A retrospective analysis of pediatric kidney transplant recipients at our center from 2007 to 2014 was performed. Read More
Pediatr Dermatol 2018 Dec 9. Epub 2018 Dec 9.
Department of Dermatology and Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
A pseudoxanthoma elasticum (PXE)-like phenotype develops in a subset of patients with inherited hemoglobinopathies. Although PXE tissue changes are thought to develop in the absence of ABCC6 mutations in patients with beta-thalassemia, ABCC6 mutations have not been well evaluated among sickle cell disease patients with PXE-like disease. To our knowledge, we describe the first patient with sickle cell disease, PXE skin findings, and two confirmed pathogenic ABCC6 mutations. Read More
Pediatr Transplant 2018 Dec 9:e13329. Epub 2018 Dec 9.
Department of Pediatrics and Transplantation Center, University Hospital Motol, 2nd Medical Faculty Prague, Charles University Prague, Prague, Czech Republic.
Objectives: Strict BP control can retard progression of CKD in children. This prospective 3-year randomized controlled trial is aimed to investigate whether strict BP control can retard progression of chronic allograft dysfunction.
Methods: Twenty-three pediatric patients were randomly selected to the standard BP group (STAND, target 24-hour MAP 50-95th percentile, n = 11) or the intensified BP group (INTENS, target 24-hour MAP <50th percentile, n = 12). Read More
Pediatr Blood Cancer 2018 Dec 11:e27568. Epub 2018 Dec 11.
Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
Background: Bacillus species are known to cause severe infection in immunocompromised hosts. The incidence of Bacillus bloodstream infections and characteristics of infection among children with cancer or indication for hematopoietic cell transplant (HCT) is unknown.
Methods: We performed a retrospective medical record review of all cases of Bacillus bacteremia between January 1, 2005, and December 31, 2014, at Boston Children's Hospital. Read More
J Rural Health 2018 Dec 7. Epub 2018 Dec 7.
RAND Corporation, Pittsburgh, Pennsylvania.
Purpose: Integrating oral health care into primary care has been promoted as a strategy to increase delivery of preventive oral health services (POHS) to young children, particularly in rural areas where few dentists practice. Using a multistate sample of Medicaid claims, we examined a child's odds of receiving POHS in a medical office by county rurality.
Methods: We used 2012-2014 Medicaid Analytic extract claims data for 6,275,456 children younger than 6 years in 39 states that allowed Medicaid payment for POHS in medical offices. Read More
Pediatr Diabetes 2018 Dec 10. Epub 2018 Dec 10.
Karolinska Institutet, Department of Clinical Science, Intervention and Technology, Division of Pediatrics, Stockholm, Sweden.
Background: Impaired fasting glycemia (IFG) reflects an intermediate hyperglycemia in the fasting state. Which fasting glucose level that actually is associated with impaired insulin-glucose homeostasis in children and adolescents with obesity is unknown.
Objective: The aim of this study was to investigate how insulin and glucose homeostasis in children and adolescents with obesity in Sweden varies within different fasting glucose levels in the non-diabetic range. Read More
Eur J Immunol 2018 Dec 7. Epub 2018 Dec 7.
Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Under homeostatic conditions, dendritic cells (DCs) continuously patrol the intestinal lamina propria. Upon antigen encounter, DCs initiate C-C motif chemokine receptor 7 (CCR7) expression and migrate into lymph nodes to direct T cell activation and differentiation. The mechanistic underpinnings of DC migration from the tissues to lymph nodes have been largely elucidated, contributing greatly to our understanding of DC functionality and intestinal immunity. Read More
J Trauma Stress 2018 Dec 11. Epub 2018 Dec 11.
Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA.
There is a relative lack of research on distress tolerance (DT) in veteran samples. The aims of the study were to (a) evaluate convergent and discriminant validity of a behavioral measure of DT compared to theoretically similar (i.e. Read More
Mov Disord 2018 Dec 10. Epub 2018 Dec 10.
MIND Institute, UC Davis Medical Center, Sacramento, California, USA.
Background: Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder associated with premutation alleles of the FMR1 gene. Expansions of more than 200 CGG repeats give rise to fragile X syndrome, the most common inherited form of cognitive impairment. Fragile X-associated tremor/ataxia syndrome is characterized by cerebellar tremor and ataxia, and the presence of ubiquitin-positive inclusions in neurons and astrocytes. Read More
Acta Paediatr 2018 Dec 8. Epub 2018 Dec 8.
Director of Paediatric Pain and Palliative Care Service, Department of Women's and Children's Health, University Hospital, Padua, Italy.
Pain is a major cause of admissions to pediatric emergency departments, but is often inappropriately managed (1). The findings of the Pain Practice in Italian Pediatric Emergency Departments on the appropriate use of paracetamol and ibuprofen have previously been reported (1,2). This multicentre, retrospective study evaluated the prescription of opioids given to patients up to the age of 14 with acute non-procedural pain by 18 Italian emergency departments between October 2014 and January 2015. Read More
Am J Hematol 2018 Dec 8. Epub 2018 Dec 8.
Department of Pediatric Haematology, Evelina Children's Hospital, Guy's and St. Thomas NHS Trust, London, United Kingdom.
Prenat Diagn 2018 Dec 9. Epub 2018 Dec 9.
Department of Pediatric Imaging, CHU Montpellier, Montpellier, France.
Objective: To assess specific, direct, and indirect prenatal ultrasound features in cases of fetal midgut volvulus.
Methods: Retrospective case series of neonatal volvulus, based on postnatal and prenatal imaging findings that occurred from 2006-2017. Prenatal and postnatal signs including the specific "whirlpool sign" were computed. Read More
J Dermatol 2018 Dec 7. Epub 2018 Dec 7.
Department of Dermatology, Graduate School of Medicine, Mie University, Tsu, Japan.
J Cell Physiol 2018 Dec 7. Epub 2018 Dec 7.
Department of Biomedical Sciences, University of Bologna, Bologna, Italy.
Osteosarcoma (OS) is the most common pediatric malignant neoplasia of the skeletal system. It is characterized by a high degree of malignancy and a severe tendency to metastasize. In the past decade, many studies have provided evidence that the phosphoinositide 3-kinase (PI3K) signaling pathway is one of the most frequently altered pathways in human cancer, and has a critical role in driving tumor initiation and progression. Read More
J Dermatol 2018 Dec 10. Epub 2018 Dec 10.
Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan.
Laryngoscope 2018 Dec 8. Epub 2018 Dec 8.
Division of Otolaryngology, Department of Surgery, Akron Childrens Hospital Akron, Ohio, U.S.A.
Objectives: Despite the importance, impact, and prevalence of pediatric hearing loss (HL), there are very few published clinical practice guidelines (CPG) supporting the evaluation and management of pediatric patients with HL. Our objective was to appraise existing CPGs to ensure safe and effective practices.
Methods: A literature search was conducted in PubMed, Google Scholar, EBSCO, as well as a manual Google search. Read More
Pediatr Transplant 2018 Dec 7:e13335. Epub 2018 Dec 7.
Department of Pediatrics (Cardiology), Stanford University Medical Center, Stanford University, Stanford, California.
Danon disease (DD) is an X-linked dominant disorder caused by a mutation in the lysosomal-associated membrane protein-2 (LAMP-2) gene coding for the LAMP-2 protein. We report two cases of successful heart transplantation (HT) in adolescent brothers with DD, including one who was bridged to HT for 34 days with a HeartWare left ventricular assist device. In both patients, the post-transplant course was complicated by profound skeletal muscle weakness that resolved with corticosteroid withdrawal. Read More
J Cell Mol Med 2018 Dec 7. Epub 2018 Dec 7.
Department of Pathology, Laboratory for Experimental Patho-Oncology, Erasmus MC University Medical Center, Cancer Institute, Rotterdam, The Netherlands.
Germ cell tumours predominantly of the testis ((T)GCTs) are remarkably chemotherapy sensitive. However, a small proportion of patients fail to be cured with cisplatin-based combination chemotherapy. miR-371a-3p is a new liquid biopsy biomarker for (T)GCTs. Read More
Pediatr Blood Cancer 2018 Dec 10:e27574. Epub 2018 Dec 10.
Department of Pediatrics, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, Tamil Nadu, India.
Congenit Heart Dis 2018 Dec 11. Epub 2018 Dec 11.
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee.
Even though up to 60% of premature infants less than 28 weeks gestation develop persistent patent ductus arteriosus (PDA), there remains controversy regarding if, when, and how to close the PDA. Failure to close the PDA has been associated with significant morbidity but no cause-and-effect has been proven for short-term or long-term outcomes in modern times. Surgical closure has the advantage of eliminating the PDA, but short-term complications and long-term adverse outcomes are worrisome. Read More
Magn Reson Med 2018 Dec 7. Epub 2018 Dec 7.
Department of Brain Repair and Rehabilitation, University College London Queen Square Institute of Neurology, Queen Square, London, United Kingdom.
Purpose: To develop a robust renal arterial spin labeling (ASL) acquisition and processing strategy for mapping renal blood flow (RBF) in a pediatric cohort with severe kidney disease.
Methods: A single-shot background-suppressed 3D gradient and spin-echo (GRASE) flow-sensitive alternating inversion recovery (FAIR) ASL acquisition method was used to perform 2 studies. First, an evaluation of the feasibility of single-shot 3D-GRASE and retrospective noise reduction methods was performed in healthy volunteers. Read More
Dev Med Child Neurol 2018 Dec 10. Epub 2018 Dec 10.
Department of Population Health Sciences and Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Acta Paediatr 2018 Dec 7. Epub 2018 Dec 7.
Inserm, UMR1153, Centre de Recherche en Épidémiologie et Statistique Sorbonne Paris Cité (CRESS), équipe Épidémiologie Périnatale, Obstétricale et Pédiatrique (ÉPOPé) Labex GR-Ex, Paris, France.
Sacri A-S, de Lauzon-Guillain B, Dufourg M-D, Bois C, Charles M A, Chalumeau M. Iron-fortified formula use in young children and association with socioeconomic factors in the French nationwide ELFE cohort.
Aim: To study the rate of iron-fortified infant formula (IFF) use in young children in France and its association with socioeconomic factors. Read More
Pediatr Transplant 2018 Dec 7:e13327. Epub 2018 Dec 7.
Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Our main goal with this study was to share our off-label experience with CEUS for identifying circulatory complications after liver transplantation in children. A total of 74 CEUS examinations performed on 34 pediatric patients who underwent a liver transplant were retrospectively included. About 53% of the examinations were performed on children 2 years old or younger. Read More
Am J Hematol 2018 Dec 8. Epub 2018 Dec 8.
Dana Farber and Boston Children's Cancer and Blood Disorders Center, Boston, MA.
Identification of genetic causes of neutropenia informs precision medicine approaches to medical management and treatment. Accurate diagnosis of genetic neutropenia disorders informs treatment options, enables risk stratification, cancer surveillance, and attention to associated medical complications. The rapidly expanding genetic testing options for the evaluation of neutropenia have led to exciting advances but also new challenges. Read More