1,367 results match your criteria Peak Flow Rate Measurement


Performance characteristics of the digital Biograph Vision PET/CT system.

J Nucl Med 2019 Jan 10. Epub 2019 Jan 10.

University Medical Center Groningen, Netherlands.

This study evaluates the performance of the Siemens Biograph Vision digital PET/CT system (Siemens Healthineers, Knoxville, USA) according to the NEMA NU 2-2012 standard (published by the National Electrical Manufacturers Association (NEMA)) to allow for a reliable, reproducible, and inter-system comparable performance measurement. The new digital PET/CT features silicon photomultiplier (SiPM)-based detectors with 3.2 mm lutetium oxyorthosilicate (LSO) crystals and full coverage of the scintillator area. Read More

View Article

Download full-text PDF

Source
http://jnm.snmjournals.org/lookup/doi/10.2967/jnumed.118.215
Publisher Site
http://dx.doi.org/10.2967/jnumed.118.215418DOI Listing
January 2019
5 Reads

Growth of perovskite nanocrystals in poly-tetra fluoroethylene based microsystem: On-line and off-line measurements.

Nanotechnology 2019 Jan 10. Epub 2019 Jan 10.

Department of Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506, USA, Lexington, UNITED STATES.

Cesium lead halide perovskite nanocrystals are photoelectric nanomaterials that have potential applications in a variety of areas due to their excellent photoelectric and tunable photoluminescent properties. In this work, we investigate the synergetic effects of reaction temperature, reaction-capillary length and flow rate on the growth kinetics of perovskite nanocrystals in PTFE-based microsystem and the photoluminescence characteristics of the perovskite nanocrystals both online and offline. The on-line measurement finds that increasing the reaction temperature leads to the increase of the wavelength of the PL emission peak of the synthesized nanocrystals and reduces the average size of the perovskite nanocrystals synthesized in long reaction-capillaries. Read More

View Article

Download full-text PDF

Source
http://iopscience.iop.org/article/10.1088/1361-6528/aafd3b
Publisher Site
http://dx.doi.org/10.1088/1361-6528/aafd3bDOI Listing
January 2019
1 Read

The impact of lung function case-finding tests on smoking behaviour: A nested randomised trial within a case-finding cohort.

Health Sci Rep 2018 Jun 18;1(6):e41. Epub 2018 May 18.

Institute of Health and Society Newcastle University Newcastle upon Tyne UK.

Rationale Aims And Objectives: Increasing awareness of people's lung health through the use of lung function tests or symptom-based questionnaires is a potential method to aid smoking cessation. We investigated the impact of case-finding lung function tests for chronic obstructive pulmonary disease on smoking behaviour.

Methods: Our trial used a novel waiting list randomised controlled trial design, nested within a case-finding cohort study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hsr2.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266471PMC

Vortex Whistle and Smart Phone Application for Peak Flow Recordings in Asthmatic Children: A Feasibility Study.

Telemed J E Health 2018 Dec 20. Epub 2018 Dec 20.

1 Department of Pediatrics, Stavanger University Hospital, Stavanger, Norway.

Introduction: Variable airflow obstruction that can be confirmed by diurnal variability of peak expiratory flow (PEF) >13% is an important characteristic of asthma. Home monitoring of PEF may be helpful to diagnose and monitor asthma. In this feasibility study, we aimed to study if asthmatic children can measure PEF at home twice daily during a 4-week period using a device designed as a "whistle" and a smart phone software application. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/tmj.2018.0270DOI Listing
December 2018

Design and Implementation of Respiration Rate Measurement System Using an Information Filter on an Embedded Device.

Sensors (Basel) 2018 Nov 30;18(12). Epub 2018 Nov 30.

Robotics Group, Korea Institute of Industrial Technology, Gyeonggi-do, Ansan-si 15588, Korea.

In this work, an algorithm was developed to measure respiration rate for an embedded device that can be used by a field robot for relief operations. With this algorithm, the rate measurement was calculated based on direct influences of respiratory-induced intensity variation (RIIV) on blood flow in cardiovascular pathways. For this, a photoplethysmogram (PPG) sensor was used to determine changes in heartbeat frequencies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/s18124208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308642PMC
November 2018
6 Reads

Leachate generation rate modeling using artificial intelligence algorithms aided by input optimization method for an MSW landfill.

Environ Sci Pollut Res Int 2018 Dec 3. Epub 2018 Dec 3.

Civil Engineering Department, University of Malaya, 50603, Kuala Lumpur, Malaysia.

Leachate is one of the main surface water pollution sources in Selangor State (SS), Malaysia. The prediction of leachate amounts is elementary in sustainable waste management and leachate treatment processes, before discharging to surrounding environment. In developing countries, the accurate evaluation of leachate generation rates has often considered a challenge due to the lack of reliable data and high measurement costs. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11356-018-3749-5
Publisher Site
http://dx.doi.org/10.1007/s11356-018-3749-5DOI Listing
December 2018
2 Reads

Study of the column efficiency using gradient elution based on Van Deemter plots.

J Chromatogr A 2019 Jan 22;1584:126-134. Epub 2018 Nov 22.

Departament de Química Analítica, Universitat de València, c/Dr. Moliner 50, 46100 Burjassot, Spain.

Performance of chromatographic columns is of major importance in the development of more efficient separation methods. So far, a common practice is to study the column behavior in isocratic elution by modifying the flow rate and fitting the theoretical plate height values versus the mobile phase linear velocity, according to the Van Deemter equation. In this work, an approach is presented to extend the measurement of efficiency to linear gradient elution, where the mean retention factor is kept constant at each assayed flow. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chroma.2018.11.042DOI Listing
January 2019

Industrial radiotracer application in flow rate measurement and flowmeter calibration using Tc and Au nanoparticles radioisotope.

Appl Radiat Isot 2019 Jan 12;143:24-28. Epub 2018 Oct 12.

Plant Assessment Technology Group, Malaysian Nuclear Agency, 43000 Kajang, Malaysia. Electronic address:

The flow rate or fluid velocity measurement is important to maintain fluid flow quality performance in the systems. This study focuses on determination of volumetric flow rate measurement and to calibrate the conventional flowmeter using industrial radiotracer approach in quadrilateral gas-liquid bubble column reactor. In this work, two different radioisotopes which emit γ-ray have been chosen as radioactive tracer which is Tc produced from Mo/Tc radioisotope generator and Au nanoparticle form neutron activation at research nuclear reactor TRIGA Mark II. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09698043173148
Publisher Site
http://dx.doi.org/10.1016/j.apradiso.2018.10.008DOI Listing
January 2019
7 Reads

End tidal carbon dioxide monitoring in acute asthma: a prospective pilot study in emergency department patients.

Eur J Emerg Med 2018 Oct 22. Epub 2018 Oct 22.

Emergency Department Lariboisière Hospital, AP-HP, 2 rue Ambroise Paré, Paris, University Paris VII René Diderot.

Background: The peak expiratory flow rate (PEFR) is the gold standard for monitoring asthmatic patients. However, its measurement requires understanding and active participation. End tidal carbon dioxide (EtCO2) may be considered an accurate surrogate for PaCO2, a severity marker in acute asthma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MEJ.0000000000000581DOI Listing
October 2018
1 Read

Health hazards and risks for musculoskeletal problems among child labourers in the brickfield sector of West Bengal, India.

Authors:
Banibrata Das

Int Health 2018 Oct 17. Epub 2018 Oct 17.

Department of Physiology, South Calcutta Girls' College, University of Calcutta, Kolkata, India.

Aims: The purpose of this study was to describe the health hazards among child labourers in brickfields, and to assess occupational health problems, together with physiological and respiratory stress, compared with child control subjects.

Methods: A cross-sectional study was conducted on 112 child brickfield workers and 120 control subjects, and a modified Nordic Questionnaire was applied to assess the discomfort felt among both groups of workers. Physiological assessment of the workload was carried out by the measurement of heart rate, blood pressure and spirometry of the workers. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/inthealth/advance-article/doi/10.10
Publisher Site
http://dx.doi.org/10.1093/inthealth/ihy071DOI Listing
October 2018
3 Reads
1.797 Impact Factor

Inter-Laboratory Characterization of the Velocity Field in the FDA Blood Pump Model Using Particle Image Velocimetry (PIV).

Cardiovasc Eng Technol 2018 Dec 5;9(4):623-640. Epub 2018 Oct 5.

Food & Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD, USA.

Purpose: A credible computational fluid dynamics (CFD) model can play a meaningful role in evaluating the safety and performance of medical devices. A key step towards establishing model credibility is to first validate CFD models with benchmark experimental datasets to minimize model-form errors before applying the credibility assessment process to more complex medical devices. However, validation studies to establish benchmark datasets can be cost prohibitive and difficult to perform. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s13239-018-00378-y
Publisher Site
http://dx.doi.org/10.1007/s13239-018-00378-yDOI Listing
December 2018
16 Reads

The use of 5% lidocaine medicated plaster for acute postoperative pain after gynecological surgery: A pilot randomized controlled feasibility trial.

Medicine (Baltimore) 2018 Sep;97(39):e12582

Department of Anaesthesia and Intensive Care, Prince of Wales Hospital.

Objectives: To examine the feasibility and potential efficacy of 5% lidocaine medicated plaster for acute postoperative pain in a parallel, blinded, randomized controlled pilot trial.

Methods: Twenty-eight women undergoing elective gynecological surgery with midline incisions were randomly allocated 5% lidocaine medicated patch (Lignopad) or placebo plasters. Postoperative pain at rest and on movement at 24 hours were the primary study endpoints, with secondary endpoints of postoperative pain within the first 48 hours, cumulative morphine consumption (mg), predicted peak flow rate (PFR) (%) and adverse effects. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00005792-201809280-0009
Publisher Site
http://dx.doi.org/10.1097/MD.0000000000012582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181576PMC
September 2018
9 Reads

The application of commercially available mobile cigarette topography devices for e-cigarette vaping behavior measurements.

Nicotine Tob Res 2018 Sep 12. Epub 2018 Sep 12.

University of Maryland, College Park, MD, USA.

Introduction: The ability to reliably measure real-world vaping behavior is critical to understand exposures to potential toxins. Commercially available mobile topography devices were originally designed to measure cigarette puffing behavior. Information regarding how applicable these devices are to the measurement of e-cigarette vaping topography is needed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ntr/nty190DOI Listing
September 2018
1 Read

Biventricular morphology in adults born with a ventricular septal defect.

Cardiol Young 2018 Dec 30;28(12):1379-1385. Epub 2018 Aug 30.

1Department of Cardiothoracic and Vascular Surgery,Aarhus University Hospital,Aarhus,Denmark.

Ventricular septal defects - large, surgically closed or small, untreated - have demonstrated lower peak exercise capacity compared with healthy controls. The mechanisms behind these findings are not yet fully understood. Therefore, we evaluated biventricular morphology in adults with a ventricular septal defect using MRI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1047951118001361DOI Listing
December 2018
11 Reads

First trimester ductus venosus velocity ratios as a marker for major cardiac defects.

Ultrasound Obstet Gynecol 2018 Aug 20. Epub 2018 Aug 20.

Department of Obstetrics and Gynaecology, University of Tuebingen, Germany.

Objective: To examine the DV flow in fetuses with and without a cardiac defect. In addition to the standard assessment of the DV PIV and the a-wave, we evaluated different phases of the DV flow.

Methods: Retrospective study including singleton pregnancies that underwent first trimester screening, which included DV flow assessment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/uog.20099DOI Listing
August 2018
8 Reads

Aptamer-functionalized AuNPs for the high-sensitivity colorimetric detection of melamine in milk samples.

PLoS One 2018 2;13(8):e0201626. Epub 2018 Aug 2.

College of Life Sciences, Henan Agricultural University, Zhengzhou, China.

Although aptamer-functionalized AuNPs technology exhibits great potential in analytical and biological chemistry, direct analysis of molecules at a low concentration using colorimetric assay remains challenging. The development of intuitive methods has attracted interest for promising detection of melamine in milk samples due to a demand for stable and understandable process. In this study, we propose a rapid and facile colorimetric measurement method of melamine combined aptamer-functionalized AuNPs in contaminated milk samples. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201626PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072046PMC
August 2018
1 Read

Estimation of Cough Peak Flow Using Cough Sounds.

Sensors (Basel) 2018 Jul 22;18(7). Epub 2018 Jul 22.

Department of System Cybernetics, Institute of Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8527, Japan.

Cough peak flow (CPF) is a measurement for evaluating the risk of cough dysfunction and can be measured using various devices, such as spirometers. However, complex device setup and the face mask required to be firmly attached to the mouth impose burdens on both patients and their caregivers. Therefore, this study develops a novel cough strength evaluation method using cough sounds. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/s18072381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068958PMC
July 2018
1 Read

High-Frame-Rate Contrast-enhanced US Particle Image Velocimetry in the Abdominal Aorta: First Human Results.

Radiology 2018 Oct 17;289(1):119-125. Epub 2018 Jul 17.

From the Department of Vascular Surgery, Rijnstate Hospital, Wagnerlaan 55, 6815 AD Arnhem, the Netherlands (S.E., M.M.P.J.R., E.G.J.); Department of Biomedical Engineering, Thorax Center ( J.V., H.J.V., F.J.H.G., N.d.J., J.G.B.), and Department of Gastroenterology and Hepatology (P.T.), Erasmus Medical Center, Rotterdam, the Netherlands; Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands ( J.J.M.W.); Physics of Fluids Group, Technical Medical ( TechMed ) Centre, University of Twente, Enschede, the Netherlands (M.V., E.G.J.); and Department of Imaging Physics, Faculty of Applied Sciences, Delft University of Technology, Delft, the Netherlands (N.d.J.).

Purpose To study the feasibility of high-frame-rate (HFR) contrast material-enhanced (CE) ultrasound particle image velocimetry (PIV), or echo PIV, in the abdominal aorta. Materials and Methods Fifteen healthy participants (six men; median age, 23 years [age range, 18-34 years]; median body mass index, 20.3 kg/m [range, 17. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1148/radiol.2018172979DOI Listing
October 2018
1 Read

3-D Velocity and Volume Flow Measurement In Vivo Using Speckle Decorrelation and 2-D High-Frame-Rate Contrast-Enhanced Ultrasound.

IEEE Trans Ultrason Ferroelectr Freq Control 2018 Dec 27;65(12):2233-2244. Epub 2018 Jun 27.

Being able to measure 3-D flow velocity and volumetric flow rate effectively in the cardiovascular system is valuable but remains a significant challenge in both clinical practice and research. Currently, there has not been an effective and practical solution to the measurement of volume flow using ultrasound imaging systems due to challenges in existing 3-D imaging techniques and high system cost. In this study, a new technique for quantifying volumetric flow rate from the cross-sectional imaging plane of the blood vessel was developed by using speckle decorrelation (SDC), 2-D high-frame-rate imaging with a standard 1-D array transducer, microbubble contrast agents, and ultrasound imaging velocimetry (UIV). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/TUFFC.2018.2850535DOI Listing
December 2018
11 Reads

Tidal breathing parameters measured by structured light plethysmography in children aged 2-12 years recovering from acute asthma/wheeze compared with healthy children.

Physiol Rep 2018 Jun;6(12):e13752

University Hospitals of North Midlands, Stoke-on-Trent, UK.

Measurement of lung function can be difficult in young children. Structured light plethysmography (SLP) is a novel, noncontact method of measuring tidal breathing that monitors displacement of the thoraco-abdominal wall. SLP was used to compare breathing in children recovering from an acute exacerbation of asthma/wheeze and an age-matched cohort of controls. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.14814/phy2.13752
Publisher Site
http://dx.doi.org/10.14814/phy2.13752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014477PMC
June 2018
5 Reads

Near-infrared spectroscopy using indocyanine green dye for minimally invasive measurement of respiratory and leg muscle blood flow in patients with COPD.

J Appl Physiol (1985) 2018 Sep 21;125(3):947-959. Epub 2018 Jun 21.

GP Livanos and M Simou Laboratories, Department of Critical Care Medicine and Pulmonary Services, Medical School of Athens University, Evangelismos Hospital , Athens , Greece.

Reliability of near-infrared spectroscopy, measuring indocyanine green (ICG) for minimally invasive assessment of relative muscle blood flow during exercise has been examined in fit young individuals but not in chronic obstructive pulmonary disease (COPD). Here we ask whether it could be used to evaluate respiratory and locomotor muscle perfusion in COPD patients. Vastus lateralis muscle blood flow (MBF, the reference method calculated from arterial and muscle ICG concentration curves) and a blood flow index [BFI, calculated using only the (same) muscle ICG concentration curves] were compared in 10 patients (forced expiratory volume in 1 s: 51 ± 6% predicted) at rest and during cycling at 25, 50, 75, and 100% of peak work rate (WR). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/japplphysiol.00959.2017DOI Listing
September 2018
9 Reads

Relationship of aortic excess pressure obtained using pressure-only reservoir pressure analysis to directly measured aortic flow in humans.

Physiol Meas 2018 Jun 28;39(6):064006. Epub 2018 Jun 28.

Monash Cardiovascular Research Centre, School of Clinical Science at Monash Health, Monash Health, Melbourne, Australia. Joint first authors.

Objectives: A reservoir pressure model describing left ventricular-large artery interaction has been proposed as a useful heuristic model providing insight into the propagation of the central blood pressure as well as providing clinical prognostic information. A pressure-only approach to calculation of reservoir pressure waves has been proposed but this assumes that the resultant excess pressure is proportional to the volume flow rate out of the left ventricle; this has not been tested in humans.

Approach: We use non-invasively acquired central pressure and flow data obtained in the 2nd Australian National Blood Pressure Study to test this assumption and to investigate the use of flow approximations based on excess pressure or an assumed triangular flow pattern in calculation of forward and backwards waves in the aortic root. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1088/1361-6579/aaca87DOI Listing

GC quantitative analysis of benzyl isothiocyanate in roots extract and dental care herbal products.

Saudi Pharm J 2018 May 11;26(4):462-466. Epub 2018 Feb 11.

Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Al-Kharj 11942, Saudi Arabia.

An accurate, sensitive, precise and simple method was developed utilizing Gas Chromatography for the quantitative analysis of benzyl isothicyanate in Siwak extract and dental care herbal products claimed to contain Siwak. Rtx (30.0 m × 0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsps.2018.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961752PMC
May 2018
5 Reads

Quantitative Blood Flow Assessment by Multiparameter Analysis of Indocyanine Green Video Angiography.

World Neurosurg 2018 Aug 3;116:e187-e193. Epub 2018 May 3.

Department of Neurosurgery, Asahikawa Medical University, Hokkaido, Japan. Electronic address:

Background: Measurements of quantitative blood flow are crucial during brain vascular surgery. Indocyanine green video angiography (ICG-VAG) is an accepted method of blood flow visualization; however, quantitative techniques have not yet been established. Thus, the aim of this study was to further develop ICG analysis for visualizing intraoperative flow changes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2018.04.148DOI Listing
August 2018
4 Reads

Effect of dietary nitrate supplementation on conduit artery blood flow, muscle oxygenation, and metabolic rate during handgrip exercise.

J Appl Physiol (1985) 2018 Aug 3;125(2):254-262. Epub 2018 May 3.

Department of Kinesiology, Kansas State University , Manhattan, Kansas.

Dietary nitrate supplementation has positive effects on mitochondrial and muscle contractile efficiency during large muscle mass exercise in humans and on skeletal muscle blood flow (Q̇) in rats. However, concurrent measurement of these effects has not been performed in humans. Therefore, we assessed the influence of nitrate supplementation on Q̇ and muscle oxygenation characteristics during moderate- (40 %peak) and severe-intensity(85% peak) handgrip exercise in a randomized, double-blind, crossover design. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/japplphysiol.00772.2017DOI Listing
August 2018
2 Reads

Patient experience of nasal obstruction and its clinical assessment.

J Laryngol Otol 2018 Apr 7;132(4):318-322. Epub 2018 Mar 7.

Department of Rhinology and Facial Plastic Surgery,Royal National Throat,Nose and Ear Hospital,London,UK.

Background: The correlation between objective and subjective nasal obstruction is poor, and dissatisfaction rates after surgery for nasal obstruction are high. Accordingly, novel assessment techniques may be required. This survey aimed to determine patient experience and preferences for the measurement of nasal obstruction. Read More

View Article

Download full-text PDF

Source
https://www.cambridge.org/core/product/identifier/S002221511
Publisher Site
http://dx.doi.org/10.1017/S0022215117002146DOI Listing
April 2018
2 Reads

Comparative study on the analgesic effect of acute ipsilateral shoulder pain after open thoracotomy between preoperative ultrasound guided suprascapular nerve block (SNB) and intraoperative phrenic nerve infiltration (PNI) in cancer lung patients.

J Egypt Natl Canc Inst 2018 Mar 7;30(1):27-31. Epub 2018 Feb 7.

Department of Anaesthesia, National Cancer Institute, Cairo University, Egypt.

Introduction: Acute ipsilateral shoulder pain (ISP) is a common complaint in patients after thoracotomy. The incidence ranges from 21% to 97%. Unfortunately, clinical studies did not put enough focus on ISP post thoracic surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jnci.2018.01.003DOI Listing
March 2018
6 Reads

Effect of Mannitol on Ultrasonographically Measured Optic Nerve Sheath Diameter as a Surrogate for Intracranial Pressure During Robot-Assisted Laparoscopic Prostatectomy with Pneumoperitoneum and the Trendelenburg Position.

J Endourol 2018 Jul 13;32(7):608-613. Epub 2018 Mar 13.

3 Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine , Seoul, Korea.

Introduction: CO pneumoperitoneum and the steep Trendelenburg position during robot-assisted laparoscopic prostatectomy (RALP) can increase intracranial pressure (ICP). Mannitol is widely used to treat increased ICP. However, no studies to date have specifically evaluated the effect of mannitol on ICP in patients undergoing RALP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/end.2017.0828DOI Listing
July 2018
6 Reads

Development and validation of a high-performance liquid chromatography method for the quantitation of intracellular PARP inhibitor Olaparib in cancer cells.

J Pharm Biomed Anal 2018 Apr 31;152:74-80. Epub 2018 Jan 31.

Université Clermont Auvergne, Institut Universitaire de Technologie, INSERM, U1240 Imagerie Moléculaire et Stratégies Théranostiques, F-63000 Clermont Ferrand, France.

Olaparib is a potent PARP inhibitor in clinical use for cancer therapy. A bioanalytical assay was developed and validated for quantitation of intracellular level of olaparib in cells exposed to the drug. The assay involves an optimized and straightforward sample pretreatment with acetonitrile for olaparib solubilization, cell lysis and protein precipitation, and a high performance liquid chromatography (HPLC) method with ultraviolet detection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpba.2018.01.036DOI Listing
April 2018
20 Reads

Dobutamine Stress Echocardiography for Management of Low-Flow, Low-Gradient Aortic Stenosis.

J Am Coll Cardiol 2018 Feb;71(5):475-485

Institut Universitaire de Cardiologie et de Pneumologie, Université Laval, Québec, Canada; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota. Electronic address:

Background: In the American College of Cardiology/American Heart Association guidelines, patients are considered to have true-severe stenosis when the mean gradient (MG) is ≥40 mm Hg with an aortic valve area (AVA) ≤1 cm during dobutamine stress echocardiography (DSE). However, these criteria have not been previously validated.

Objectives: The aim of this study was to assess the value of these criteria to predict the presence of true-severe AS and the occurrence of death in patients with low-flow, low-gradient aortic stenosis (LF-LG AS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2017.11.052DOI Listing
February 2018
7 Reads

Analysis of the clinical value of fractional flow reserve for prognosis evaluation of patients of percutaneous coronary intervention.

Exp Ther Med 2018 Jan 1;15(1):673-678. Epub 2017 Nov 1.

Department of Cardiology, Tangshan Workers' Hospital, Tangshan, Hebei 063000, P.R. China.

We investigated the clinical value of fractional flow reserve (FFR) for the prognostic evaluation of patients with percutaneous coronary intervention. We enrolled 120 patients who were admitted to the hospital to undergo percutaneous coronary intervention for acute coronary syndromes between May 2014 and June 2015. The 120 patients were divided into two groups, the observation group and the control group, according to the post-surgery level of FFR. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/etm.2017.5433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769269PMC
January 2018
9 Reads

Pretreatment Prediction of the Outcomes of Intranasal Steroid Sprays in Cases with Inferior Turbinate Hypertrophy.

Turk Arch Otorhinolaryngol 2017 Sep 14;55(3):105-110. Epub 2017 Aug 14.

Clinic of Otorhinolaryngology, Haseki Training and Research Hospital, İstanbul, Turkey.

Objective: Intranasal steroid sprays (INSS) are frequently prescribed for treating inferior turbinate hypertrophy (ITH). Complications due to the long-term application of INSS such as crusting, epistaxis, nasal mucosa dryness, and septal perforation may occur. Predicting patients who would benefit from INSS early might lower treatment costs and complication rates. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5152/tao.2017.2443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782987PMC
September 2017
1 Read

The noninvasive simultaneous measurement of tissue oxygenation and microvascular hemodynamics during incremental handgrip exercise.

J Appl Physiol (1985) 2018 Mar 14;124(3):604-614. Epub 2017 Dec 14.

Department of Kinesiology, Kansas State University , Manhattan, Kansas.

Limb blood flow increases linearly with exercise intensity; however, invasive measurements of muscle microvascular blood flow during incremental exercise have demonstrated submaximal plateaus. We tested the hypotheses that 1) brachial artery blood flow (Q̇) would increase with increasing exercise intensity until task failure, 2) blood flow index of the flexor digitorum superficialis (BFI) measured noninvasively via diffuse correlation spectroscopy would plateau at a submaximal work rate, and 3) muscle oxygenation characteristics (total-[heme], deoxy-[heme], and percentage saturation) measured noninvasively with near-infrared spectroscopy would demonstrate a plateau at a similar work rate as BFI. Sixteen subjects (23. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/japplphysiol.00815.2017DOI Listing
March 2018
3 Reads

Associations between microalbuminuria and parameters of flow-mediated vasodilatation obtained by continuous measurement approaches.

Clin Exp Hypertens 2018 19;40(8):715-720. Epub 2018 Jan 19.

b Department of Cardiology , Fukuoka University School of Medicine , Fukuoka , Japan.

The associations between microalbuminuria and various parameters of flow-mediated vasodilatation (FMD) are not completely understood. We retrospectively analyzed 265 consecutive patients who underwent coronary angiography and in whom we could measure FMD and the urine albumin-creatinine ratio (UACR). Using 15 continuous measurement approaches, we measured FMD as the magnitude of the percentage change in the brachial artery diameter from baseline to peak (bFMD), the maximum FMD rate calculated as the maximal slope of dilation (FMD-MDR), and the integrated FMD response calculated as the area under the dilation curve during the 60- and 120-s dilation periods (FMD-AUC60 and FMD-AUC120). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10641963.2018.1425422DOI Listing
December 2018
3 Reads

On-tubing fluorescence measurements of the band broadening of contemporary injectors in ultra-high performance liquid chromatography.

J Chromatogr A 2018 Feb 15;1535:44-54. Epub 2017 Dec 15.

Department of Chemical Engineering, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

We report on a detailed study of the injection contribution to band broadening in contemporary UHPLC-instruments, using either flow-through needle or fixed loop injection (full loop). Using on-tubing fluorescence measurements at the outlet of the injector valve, very localized and undisturbed measurements were obtained. Varying both the flow rate and the injected volume allowed to split the injection variance (σ) in a volumetric component (related to the amount injected) and a hydrodynamic component (related to the flow rate). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chroma.2017.12.032DOI Listing
February 2018
4 Reads

Flow-Cell-Induced Dispersion in Flow-through Absorbance Detection Systems: True Column Effluent Peak Variance.

Anal Chem 2018 02 16;90(3):2063-2069. Epub 2018 Jan 16.

Agilent Technologies, Hewlett-Packard Strasse 8, D 76337 Waldbronn, Germany.

Following a brief overview of the emergence of absorbance detection in liquid chromatography, we focus on the dispersion caused by the absorbance measurement cell and its inlet. A simple experiment is proposed wherein chromatographic flow and conditions are held constant but a variable portion of the column effluent is directed into the detector. The temporal peak variance (σ), which increases as the flow rate (F) through the detector decreases, is found to be well-described as a quadratic function of /. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.7b04248DOI Listing
February 2018
3 Reads

Measuring voluntary and reflexive cough strength in healthy individuals.

Respir Med 2017 Nov 27;132:95-101. Epub 2017 Sep 27.

The University of Canterbury Rose Centre for Stroke Recovery & Research, St George's Medical Centre, Christchurch, New Zealand; Department of Communication Disorders, University of Canterbury, Christchurch, New Zealand.

Background: Cough reflex testing is a validated tool for identifying patients at risk of silent aspiration. However, inter- and intra-rater reliabilities of perceptual judgements of cough strength are sub-optimal. Although there are clinically established methods for measuring volitional cough strength, no similar methods are identified for reflexive cough strength. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09546111173033
Publisher Site
http://dx.doi.org/10.1016/j.rmed.2017.09.013DOI Listing
November 2017
7 Reads

Weekly self-measurement of FEV1 and PEF and its impact on ACQ (asthma control questionnaire)-scores: 12-week observational study with 76 patients.

NPJ Prim Care Respir Med 2017 Dec 8;27(1):64. Epub 2017 Dec 8.

Technical University of Munich, TUM School of Medicine, Institute of General Practice, Munich, Germany.

The "Asthma Control Questionnaire" (ACQ) is a very common questionnaire for assessing asthma control. This study compares different ACQ versions in a self-monitoring program over a 12-week period combining them with patients' self-measurements of peak expiratory flow (PEF) and forced expiratory volume in one second (FEV1). The objective was to test the feasibility of FEV1-self-measurements and to compare ACQ versions regarding possible additional information given by lung function. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41533-017-0064-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722863PMC
December 2017
5 Reads

Effects of treatment changes on asthma phenotype prevalence and airway neutrophil function.

BMC Pulm Med 2017 Dec 4;17(1):169. Epub 2017 Dec 4.

Centre for Public Health Research, Massey University Wellington Campus, Private Box 756, Wellington, 6140, New Zealand.

Background: Asthma inflammatory phenotypes are often defined by relative cell counts of airway eosinophils/neutrophils. However, the importance of neutrophilia remains unclear, as does the effect of ICS treatment on asthma phenotypes and airway neutrophil function. The purpose of this study was to assess asthma phenotype prevalence/characteristics in a community setting, and, in a nested preliminary study, determine how treatment changes affect phenotype stability and inflammation, with particular focus on airway neutrophils. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12890-017-0511-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715501PMC
December 2017
11 Reads

Exercise performance, haemodynamics, and respiratory pattern do not identify heart failure patients who end exercise with dyspnoea from those with fatigue.

ESC Heart Fail 2018 02 24;5(1):115-119. Epub 2017 Nov 24.

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Aims: The two main symptoms referred by chronic heart failure (HF) patients as the causes of exercise termination during maximal cardiopulmonary exercise testing (CPET) are muscular fatigue and dyspnoea. So far, a physiological explanation why some HF patients end exercise because of dyspnoea and others because of fatigue is not available. We assessed whether patients referring dyspnoea or muscular fatigue may be distinguished by different ventilator or haemodynamic behaviours during exercise. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ehf2.12207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793969PMC
February 2018
8 Reads

Verification of Non-Invasive Blood Glucose Measurement Method Based on Pulse Wave Signal Detected by FBG Sensor System.

Sensors (Basel) 2017 Nov 23;17(12). Epub 2017 Nov 23.

Graduate School of Science and Technology, Shinshu University, 3-15-1 Tokida, Ueda, Nagano 386-8567, Japan.

This paper describes and verifies a non-invasive blood glucose measurement method using a fiber Bragg grating (FBG) sensor system. The FBG sensor is installed on the radial artery, and the strain (pulse wave) that is propagated from the heartbeat is measured. The measured pulse wave signal was used as a collection of feature vectors for multivariate analysis aiming to determine the blood glucose level. Read More

View Article

Download full-text PDF

Source
http://www.mdpi.com/1424-8220/17/12/2702
Publisher Site
http://dx.doi.org/10.3390/s17122702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751605PMC
November 2017
3 Reads

Echocardiographic nomograms for upper abdominal aorta Doppler systolic wave values and systo-diastolic diameters variations in children.

J Cardiol 2018 Apr 10;71(4):394-400. Epub 2017 Nov 10.

Fondazione G. Monasterio CNR-Regione Toscana, Massa and Pisa, Italy.

Background: Abdominal aorta pulsatility and blood flow patterns are important diagnostic indicators in congenital heart disease. Reference values for these indexes are lacking.

Methods: We prospectively studied abdominal aorta pulsed-wave Doppler systolic peak velocity, deceleration time, and wave duration, and two-dimensional vessel diameters in systole and diastole in healthy Caucasian children. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jjcc.2017.09.016DOI Listing
April 2018
25 Reads

A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems.

Chem Cent J 2017 Jul 11;11(1):62. Epub 2017 Jul 11.

Department of Pharmacy, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, 200031, China.

Background: A simple, rapid and accurate stability-indicating reverse phase high performance liquid chromatography (RP-HPLC) was developed and validated for the determination of brimonidine tartrate in brimonidine tartrate/poly(2-hydroxyethyl methacrylate) (BRI/PHEMA) drug delivery contact lenses and pharmaceutical formulations.

Results: Optimum chromatographic conditions for separating brimonidine tartrate from other impurities in the leaching liquor of BRI/PHEMA drug delivery contact lenses or pharmaceutical formulations have been achieved by using a Diamonsil C18 column (150 mm × 4.6 mm, 5 μm) as a stationary phase and a mixture solution of phosphate buffer (10 mM, pH3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13065-017-0292-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505891PMC
July 2017
15 Reads

What are the clinically important outcome measures in the surgical management of nasal obstruction?

Clin Otolaryngol 2018 04 23;43(2):567-571. Epub 2017 Nov 23.

Department of Otorhinolaryngology Head and Neck Surgery, Aintree University Hospital NHS Foundation Trust, Liverpool, UK.

Objectives: To assess the correlation between the Nasal Obstruction Symptom Evaluation (NOSE) scale and peak nasal inspiratory flow (PNIF) measurement, and to determine which outcome variable correlates with patient satisfaction and thereby, provide an indication of successful surgical outcome.

Design: Prospective case series SETTING: Tertiary rhinology service (Liverpool, U.K) PARTICIPANTS: Patients having surgery (septoplasty, turbinoplasty) for nasal obstruction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/coa.13023DOI Listing
April 2018
4 Reads

Comparison between unilateral PNIF and rhinomanometry in the evaluation of nasal cycle.

Rhinology 2018 Jun;56(2):122-126

Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy.

Background: Human unilateral nasal airflow shows spontaneous changes over a period of hours due to the alternating congestion and decongestion of the venous sinuses within the nasal turbinates and nasal septum. The aim of the present study was to compare PNIF and unilateral PNIF with nasal resistances measured by means of AAR in the evaluation of the nasal cycle.

Methods: PNIF, unilateral PNIF and AAR measurements were randomly performed in 20 non-smokers, non-asthmatic volunteers, with a SNOT 22 score lower than 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4193/Rhin17.168DOI Listing
June 2018
3 Reads

Stability in neurovascular function at 3800m.

Physiol Behav 2017 Dec 28;182:62-68. Epub 2017 Sep 28.

Centre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Okanagan, Kelowna, Canada. Electronic address:

Hypoxia-induced neurocognitive impairments have been of clinical interest for centuries. The mechanisms responsible for these neurocognitive impairments at altitude are unclear, but may relate to the uncoupling of local neural activity with appropriate changes in cerebral blood flow (CBF; i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.physbeh.2017.09.023DOI Listing
December 2017
2 Reads

Peak Inspiratory Flow Rate in Chronic Obstructive Pulmonary Disease: Implications for Dry Powder Inhalers.

J Aerosol Med Pulm Drug Deliv 2017 Dec 21;30(6):381-387. Epub 2017 Sep 21.

1 Division of Pulmonary Diseases and Critical Care Medicine, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States with a significant economic burden related to hospital admissions for exacerbations. One of the primary treatment modalities for COPD is medications delivered through breath-actuated dry powdered inhalers (DPIs). For users to successfully receive inhaled medication, they must inhale with enough flow to overcome the internal resistance of the device, leading to deaggregation of the medication powder. Read More

View Article

Download full-text PDF

Source
http://www.liebertpub.com/doi/10.1089/jamp.2017.1416
Publisher Site
http://dx.doi.org/10.1089/jamp.2017.1416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915227PMC
December 2017
84 Reads
2.400 Impact Factor

Assessment of the Fetal Cerebral Artery: Importance of Doppler Preset Settings.

J Ultrasound Med 2018 Mar 6;37(3):621-628. Epub 2017 Sep 6.

Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany.

Objectives: The Doppler assessment of the middle cerebral artery (MCA) has a central role in the monitoring of high-risk pregnancies. The objective of this study was to investigate the importance of Doppler preset settings for measurement of the peak systolic velocity (PSV) and pulsatility index (PI) of the MCA.

Methods: The PI and PSV of the MCA were determined prospectively in 350 healthy fetuses between 19 and 42 weeks of pregnancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jum.14378DOI Listing
March 2018
10 Reads

The Relationship Between Uterine Artery two-dimensional Color Doppler Measurement and Pregnancy Outcome: A Prospective Observational Study.

J Reprod Infertil 2017 Apr-Jun;18(2):251-256

Department of IVF and Reproductive Medicine, Maulana Azad Medical College & Associated Lok Nayak Hospitals, New Delhi, India.

Background: The purpose of the study was to evaluate the role of uterine blood flow parameters measured by uterine artery two-dimensional (2D)-power color doppler (PCD) ultrasound in predicting fertility outcomes in women undergoing IVF-ET cycles.

Methods: In this prospective observational study, a total of 188 infertile women who underwent IVF-ET cycles were investigated. Uterine artery 2D-PD measurements were taken during early follicular phase and on day of trigger. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565912PMC
September 2017
20 Reads