1,412 results match your criteria Peak Flow Rate Measurement


Screening asymptomatic school children for early asthma by determining airway narrowing through peak expiratory flow rate measurement.

J Educ Health Promot 2020 31;9:72. Epub 2020 Mar 31.

Department of CMFM, All India Institutes of Medical Sciences, Jodhpur, Rajasthan, India.

Background: Peak expiratory flow rate (PEFR) is widely used as a predictor of treatment of asthma patients. Peak expiratory flow and forced expiratory volume in first second (FEV) are the most useful parameters for the diagnosis of asthma. Spirometry is not often available in the primary care setting, and economic factors may limit its testing. Read More

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http://dx.doi.org/10.4103/jehp.jehp_441_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255580PMC

Contemporary usefulness of pulmonary venous flow parameters to estimate left ventricular end-diastolic pressure on transthoracic echocardiography.

Int J Cardiovasc Imaging 2020 May 21. Epub 2020 May 21.

Department of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey.

Measurement of pulmonary venous flow (PVF) parameters can be used to estimate left ventricular end-diastolic pressure (LVEDP) on transthoracic echocardiography. Despite that, 2016 American Society of Echocardiography (ASE)/European Association of Cardiovascular Imaging (EACVI) algorithm gave a secondary role to PVF to assess left ventricular filling pressure. We aimed to test correlations between several PVF parameters, including novel measurements, with LVEDP and to analyze whether PVF parameters have an incremental usefulness over ASE/EACVI algorithm to estimate LVEDP. Read More

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http://dx.doi.org/10.1007/s10554-020-01886-6DOI Listing

Physiological Stratification of Patients With Angina Due to Coronary Microvascular Dysfunction.

J Am Coll Cardiol 2020 May;75(20):2538-2549

British Heart Foundation Centre of Excellence and National Institute for Health Research Biomedical Research Centre at the School of Cardiovascular Medicine and Sciences, Kings College London, London, United Kingdom. Electronic address:

Background: Coronary microvascular dysfunction (CMD) is defined by diminished flow reserve. Functional and structural CMD endotypes have recently been described, with normal and elevated minimal microvascular resistance, respectively.

Objectives: This study determined the mechanism of altered resting and maximal flow in CMD endotypes. Read More

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http://dx.doi.org/10.1016/j.jacc.2020.03.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242900PMC

Silver Nanoprism Enhanced Colorimetry for Precise Detection of Dissolved Oxygen.

Micromachines (Basel) 2020 Apr 4;11(4). Epub 2020 Apr 4.

Key Laboratory of Artificial Micro- and Nano-Structures of Ministry of Education, School of Physics and Technology, Wuhan University, Wuhan 430072, China.

Dissolved oxygen (DO) content is an essential indicator for evaluating the quality of the water body and the main parameter for water quality monitoring. The development of high-precision DO detection methods is of great significance. This paper reports an integrated optofluidic device for the high precision measurement of dissolved oxygen based on the characteristics of silver nanoprisms. Read More

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http://dx.doi.org/10.3390/mi11040383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230719PMC

Prevalence and predictors of suboptimal peak inspiratory flow rate in COPD patients.

Eur J Pharm Sci 2020 Apr 6;147:105298. Epub 2020 Mar 6.

Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. Electronic address:

The aim of this study was to determine prevalence and possible clinical predictors of suboptimal peak inspiratory flow rate (PIFR) with different dry powder inhalers. PIFR was measured across all resistance ranges of In-Check Dial® in 180 chronic obstructive pulmonary disease (COPD) subjects before hospital discharge. COPD subjects were defined as suboptimal if measured PIFR was suboptimal with any resistance representative of specific inhalers (R1-R5). Read More

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http://dx.doi.org/10.1016/j.ejps.2020.105298DOI Listing

Wall Shear Stress Measurement by Ultrafast Vector Flow Imaging for Atherosclerotic Carotid Stenosis.

Ultraschall Med 2019 Dec 19. Epub 2019 Dec 19.

INSERM U1273, Physics for Medicine, ESPCI Paris, CNRS FRE 2031, PSL Research University, Paris, France.

Objective:  Carotid plaque vulnerability assessment could guide the decision to perform endarterectomy. Ultrafast ultrasound imaging (UF) can evaluate local flow velocities over an entire 2D image, allowing measurement of the wall shear stress (WSS). We aimed at evaluating the feasibility of WSS measurement in a prospective series of patients with carotid stenosis. Read More

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http://dx.doi.org/10.1055/a-1060-0529DOI Listing
December 2019

Characterization of Focal Brain Tissue Water Measurements in Human Traumatic Brain Injury.

World Neurosurg 2020 Mar 2;135:e271-e285. Epub 2019 Dec 2.

Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA; Section of Neurosurgery, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:

Background: Cerebral edema is a major cause of morbidity in patients with severe traumatic brain injury (TBI). Intraparenchymal thermal conductivity-based probes that measure local cerebral blood flow can measure percent brain tissue water (%BTW) content, but such measures have been insufficiently characterized in patients with TBI.

Methods: We retrospectively reviewed physiologic data from patients with severe TBI treated at our institution (2014-2016) who underwent cerebral blood flow monitoring. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.11.132DOI Listing

Intranasal corticosteroids for non-allergic rhinitis.

Cochrane Database Syst Rev 2019 11 2;2019(11). Epub 2019 Nov 2.

Academic Medical Centre, Department of Otorhinolaryngology, Meibergdreef 9, A2-234, 1105 Az, Amsterdam, Netherlands.

Background: Non-allergic rhinitis is defined as dysfunction and non-infectious inflammation of the nasal mucosa that is caused by provoking agents other than allergens or microbes. It is common, with an estimated prevalence of around 10% to 20%. Patients experience symptoms of nasal obstruction, anterior rhinorrhoea/post-nasal drip and sneezing. Read More

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http://dx.doi.org/10.1002/14651858.CD010592.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824914PMC
November 2019

Left Ventricular Filling Pressures Contribute to Exercise Limitation in Patients with Continuous Flow Left Ventricular Assist Devices.

ASAIO J 2020 Mar;66(3):247-252

From the Departments of Cardiology and Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom.

We sought to determine hemodynamic mechanisms of exercise intolerance in a group of patients with the HeartWare ventricular assist device (VAD) compared to a group of heart failure patients. Twenty VAD and 22 heart failure patients underwent symptom-limited active straight leg raising exercise during right heart catheterization with thermodilution (TD), and upright cycling cardiopulmonary stress testing with cardiac output measurement by inert gas rebreathing (IGR) method. The TD and IGR exercise cardiac indexes were higher in VAD compared with heart failure group (both P < 0. Read More

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http://dx.doi.org/10.1097/MAT.0000000000001073DOI Listing
March 2020
2 Reads

Value of intra-operative Doppler sonographic measurements in predicting post-operative anastomotic leakage in rectal cancer: a prospective pilot study.

Chin Med J (Engl) 2019 Sep;132(18):2168-2176

Gastrointestinal Cancer Center, Peking University Cancer Hospital, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, China.

Background: Anastomotic leakage is a serious surgical complication in rectal cancer; however, effective evaluation methods for predicting anastomotic leakage individual risk in patients are not currently available. This study aimed to develop a method to evaluate the risk of leakage during surgery.

Methods: The 163 patients with rectal cancer, who had undergone anterior resection and low-ligation procedures for Doppler sonographic hemodynamic measurement from April 2011 to January 2015 in Peking University Cancer Hospital, were prospectively recruited. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797145PMC
September 2019
3 Reads

Vision-Based Measurement of Heart Rate from Ballistocardiographic Head Movements Using Unsupervised Clustering.

Sensors (Basel) 2019 Jul 24;19(15). Epub 2019 Jul 24.

Department of Intelligence Informatics Engineering, University of Sangmyung, Seoul 03016, Korea.

Heart rate has been measured comfortably using a camera without the skin-contact by the development of vision-based measurement. Despite the potential of the vision-based measurement, it has still presented limited ability due to the noise of illumination variance and motion artifacts. Remote ballistocardiography (BCG) was used to estimate heart rate from the ballistocardiographic head movements generated by the flow of blood through the carotid arteries. Read More

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http://dx.doi.org/10.3390/s19153263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695981PMC
July 2019
2 Reads

Peak expiratory flow as an endpoint for clinical trials in asthma: a comparison with FEV.

Respir Res 2019 Jul 18;20(1):159. Epub 2019 Jul 18.

Centre for Heart and Lung Health, Vancouver, Canada.

Background: The primary lung function endpoint in clinical trials in adolescent and adult patients with asthma is usually forced expiratory volume in one second (FEV). The objective of our analysis was to assess whether peak expiratory flow (PEF) is a suitable alternative primary lung function endpoint.

Methods: For this assessment, we calculated post hoc the correlation between pre-dose FEV and pre-dose PEF measured under supervision in the clinic and, for both lung function parameters, the correlations between supervised clinic and unsupervised home measurements, using the results from the 8 Phase III parallel-group trials of the global clinical development programme with tiotropium Respimat® in patients with asthma aged 12 to 75 years. Read More

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http://dx.doi.org/10.1186/s12931-019-1119-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637596PMC
July 2019
1 Read

On the effect of using collision/reaction cell (CRC) technology in single-particle ICP-mass spectrometry (SP-ICP-MS).

Anal Chim Acta 2019 Oct 1;1077:95-106. Epub 2019 Jun 1.

Ghent University, Department of Chemistry, Atomic & Mass Spectrometry - A&MS Research Unit, Campus Sterre, Krijgslaan 281-S12, 9000, Ghent, Belgium. Electronic address:

In this work, the effects of using collision/reaction cell (CRC) technology in quadrupole-based ICP-MS (ICP-QMS) instrumentation operated in single-particle (SP) mode have been assessed. The influence of (i) various CRC gases, (ii) gas flow rates, (iii) nanoparticle (NP) sizes and (iv) NP types was evaluated using Ag, Au and Pt NPs with both a traditional ICP-QMS instrument and a tandem ICP-mass spectrometer. It has been shown that using CRC technology brings about a significant increase in the NP signal peak width (from 0. Read More

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http://dx.doi.org/10.1016/j.aca.2019.05.077DOI Listing
October 2019
2 Reads

Arterial wall shear rate response to reactive hyperaemia is markedly different between young and older humans.

J Physiol 2019 08 15;597(16):4151-4163. Epub 2019 Jul 15.

Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.

Key Points: The vasodilatory response to reactive hyperaemia is impaired with advancing age, but it is unclear whether this is because of an altered wall shear rate (WSR) stimulus or an altered flow-mediated dilatation (FMD) response. Using new technology that allows detailed WSR measurement, we assessed the WSR-FMD response in healthy older people. Our data show that older people have a markedly altered and diminished WSR response to reactive hyperaemia compared to young people, but reduced WSR alone does not fully explain reduced FMD. Read More

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http://dx.doi.org/10.1113/JP278310DOI Listing
August 2019
5 Reads

Spirometry Measurement of Peak Inspiratory Flow Identifies Suboptimal Use of Dry Powder Inhalers in Ambulatory Patients with COPD.

Chronic Obstr Pulm Dis 2019 Jul;6(3):246-255

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Texas Medical Branch, Galveston.

Objectives: Determine the prevalence of suboptimal peak inspiratory flow rate (PIFR) and associated patient characteristics and compare PIFR measurements obtained with spirometry and In-Check DIAL device in ambulatory patients with COPD.

Methods: Patients underwent PIFR measurement with In-Check DIAL device and pulmonary function testing with calibrated equipment. Group characteristics and lung function were compared for patients with suboptimal (≤ 60 L/min) and optimal (> 60 L/min) PIFR. Read More

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http://dx.doi.org/10.15326/jcopdf.6.3.2018.0163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872217PMC
July 2019
5 Reads

An LC-MS/MS spectrometry method for the simultaneous determination of Rosuvastatin and Irbesartan in rat plasma: Insight into pharmacokinetic and drug-drug interaction studies.

J Pharm Biomed Anal 2019 Sep 31;174:226-234. Epub 2019 May 31.

Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Sharkia, 44519, Egypt.

The synergistic vascular protective effect of statins and angiotensin receptor blockers (ARBs) is well known, however, the pharmacokinetic interaction among these classes is yet to be understood and the necessity of developing analytical methods for their determination in vivo is gradually increased. Herein, first chromatographic separation coupled tandem mass spectrometric was developed and fully validated for simultaneous measurement of rosuvastatin (ROS) and irbesartan (IRB) in rat plasma after oral administration. The two analytes were extracted from plasma sample using acetonitrile-induced protein precipitation then separated on an Agilent Eclipse Plus ODS (4. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07317085193101
Publisher Site
http://dx.doi.org/10.1016/j.jpba.2019.05.069DOI Listing
September 2019
7 Reads

The Repeatability and Left Atrial Strain Analysis Obtained via Speckle Tracking Echocardiography in healthy Dogs.

J Vet Cardiol 2019 Jun 28;23:69-80. Epub 2019 Feb 28.

Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, N18 W9, Sapporo, Hokkaido, Japan.

Introduction: In left atrial (LA) strain-derived two-dimensional speckle tracking echocardiography, the reference intervals in healthy dogs can provide useful information to evaluate the LA function in dogs with heart disease.

Animals: Six laboratory beagles and 120 privately owned dogs without cardiac diseases were recruited.

Materials And Methods: The LA strain and strain rate (SR) and echocardiographic indices were obtained in dogs who underwent standard echocardiography and offline analysis for LA strain and SR measurement by speckle tracking echocardiography. Read More

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http://dx.doi.org/10.1016/j.jvc.2019.01.006DOI Listing
June 2019
5 Reads

An accurate prediction model to identify undiagnosed at-risk patients with COPD: a cross-sectional case-finding study.

NPJ Prim Care Respir Med 2019 05 28;29(1):22. Epub 2019 May 28.

Institute of Physiology, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.

Underuse or unavailability of spirometry is one of the most important factors causing underdiagnosis of COPD. We reported the development of a COPD prediction model to identify at-risk, undiagnosed COPD patients when spirometry was unavailable. This cross-sectional study enrolled subjects aged ≥40 years with respiratory symptoms and a smoking history (≥20 pack-years) in a medical center in two separate periods (development and validation cohorts). Read More

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http://www.nature.com/articles/s41533-019-0135-9
Publisher Site
http://dx.doi.org/10.1038/s41533-019-0135-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538645PMC
May 2019
11 Reads

Modal Propellant Gauging: High-resolution and non-invasive gauging of both settled and unsettled liquids in reduced gravity.

Acta Astronaut 2019 Jun 6;159:499-507. Epub 2019 Feb 6.

NASA Johnson Space Center, 2101 NASA Parkway, Houston, TX, 77058, USA.

The modal response of a liquid-filled tank to external acoustic excitation can be used to infer with high resolution the mass of contained liquid, the mass flow rate of liquids into and out of the tank, and changes in tank pressure. Both contained liquid mass and internal ullage pressure affect the modal response of the tank walls through fluid mass-loading of the tank walls and pressure-induced wall stiffening, respectively. Modal Propellant Gauging refers to the technology that exploits these shifts in modal frequencies to infer the mass of propellant in a tank. Read More

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http://dx.doi.org/10.1016/j.actaastro.2019.01.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510546PMC
June 2019
9 Reads

Respiratory Disorders among Dust Exposed Workers.

JNMA J Nepal Med Assoc 2019 Jan-Feb;57(215):14-19

All India Institute of Medical Sciences, New-Delhi, India.

Introduction: Exposure to dusts and hard physical work is common in developing industrialized countries. Acute and chronic respiratory illnesses are highly been reported from jute and textile industry. This study was undertaken to explore status of respiratory health among the workers of jute and textile industries. Read More

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November 2019
9 Reads

Association between sensitized to food allergens and childhood allergic respiratory diseases in Taiwan.

J Microbiol Immunol Infect 2019 Apr 17. Epub 2019 Apr 17.

Division of Allergy, Asthma and Rheumatology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan; School of Medicine, Chung Shan Medical University, Taichung, Taiwan. Electronic address:

Background: Sensitization to allergen has long been known to be relate to childhood allergic diseases. Polysensitised children have more severe atopic diseases, whereas allergic rhinitis or asthma children with cosensitized to food and inhalant allergens were under-researched.

Objective: To realize the association between sensitization to food allergens and pediatric allergic rhinitis and asthma in Taiwan. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S16841182183018
Publisher Site
http://dx.doi.org/10.1016/j.jmii.2019.01.005DOI Listing
April 2019
5 Reads

Relationship between handheld and clinic-based spirometry measurements in asthma patients receiving beclomethasone.

Respir Med 2019 05 20;151:35-42. Epub 2019 Mar 20.

Teva Pharmaceuticals Inc., Frazer, PA, USA. Electronic address:

Introduction: Handheld spirometers for home use by patients allow longitudinal spirometry data to be collected daily and may overcome some of the limitations of in-clinic spirometry (long intervals between measurements, results can be affected by site-based coaching and patient's asthma status during a given visit).

Objectives: To determine the relationship between spirometry values measured by clinic-based and handheld spirometers during a clinical trial.

Methods: A post hoc correlation analysis of data from a 6-week phase 3 study of beclomethasone dipropionate (BDP; delivered by breath-actuated inhaler: BAI) versus placebo in patients aged ≥12 years with persistent asthma. Read More

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http://dx.doi.org/10.1016/j.rmed.2019.03.010DOI Listing
May 2019
4 Reads

Do rebreathing manoeuvres for non-invasive measurement of cardiac output during maximum exercise test alter the main cardiopulmonary parameters?

Eur J Prev Cardiol 2019 10 25;26(15):1616-1622. Epub 2019 Apr 25.

Centro Cardiologico Monzino, IRCCS, Italy.

Background: Inert gas rebreathing has been recently described as an emergent reliable non-invasive method for cardiac output determination during exercise, allowing a relevant improvement of cardiopulmonary exercise test clinical relevance. For cardiac output measurements by inert gas rebreathing, specific respiratory manoeuvres are needed which might affect pivotal cardiopulmonary exercise test parameters, such as exercise tolerance, oxygen uptake and ventilation vs carbon dioxide output (VE/VCO) relationship slope.

Method: We retrospectively analysed cardiopulmonary exercise testing of 181 heart failure patients who underwent both cardiopulmonary exercise testing and cardiopulmonary exercise test+cardiac output within two months (average 16 ± 15 days). Read More

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http://dx.doi.org/10.1177/2047487319845967DOI Listing
October 2019
19 Reads

Effects of Prostatic Artery Embolization on the Dynamic Component of Benign Prostate Hyperplasia as Assessed by Ultrasound Elastography: A Pilot Series.

Cardiovasc Intervent Radiol 2019 Jul 16;42(7):1001-1007. Epub 2019 Apr 16.

Radiology Department, Sírio-Libanês Hospital, Adma Jafet Street, 115, Bela Vista, São Paulo, SP, 01308-050, Brazil.

Purpose: To determine the effects of prostatic artery embolization (PAE) on prostatic elasticity as assessed by Ultrasound Elastography (US-E), as well as to describe the feasibility and role of US-E as a novel tool in both pre- and post-PAE evaluation.

Materials And Methods: This is a prospective, single-center investigation that included eight patients undergoing PAE for treatment of lower urinary tract symptoms (LUTS) attributed to benign prostate hyperplasia (BPH). Baseline and 3-month follow-up evaluations were performed and included prostate-specific antigen (PSA), uroflowmetry, pelvic magnetic resonance imaging and clinical assessment using the International Prostate Symptom Score (IPSS) questionnaire and the IPSS-Quality of life (QoL) item. Read More

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http://dx.doi.org/10.1007/s00270-019-02220-xDOI Listing
July 2019
5 Reads

A Simple Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry Method for Measurement of Cortisol Level in Human Saliva.

Int J Anal Chem 2019 3;2019:4909352. Epub 2019 Mar 3.

Clinical Studies and Empirical Ethics Department, King Faisal Specialist Hospital & Research Center, MBC-03, P.O. Box 3354, Riyadh 11211, Saudi Arabia.

A simple ultraperformance liquid chromatography-tandem mass spectrometry assay for measurement of cortisol level in human saliva was developed and validated. Saliva samples containing cortisol were spiked with tolperisone as internal standard (IS) and extracted with a mixture of methyl tert-butyl ether and hexane (8:2, v:v). After solvent evaporation, residue was reconstituted in 100 l mobile phase. Read More

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http://dx.doi.org/10.1155/2019/4909352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420974PMC
March 2019
13 Reads
0.904 Impact Factor

[Feasible study of carotid artery Doppler ultrasound blood flow measurement during chest compression cardiopulmonary resuscitation].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2019 Mar;31(3):309-312

Department of Critical Care Medicine, Zhengzhou People's Hospital, Zhengzhou 450003, Henan, China.

Objective: To determine the feasibility of ultrasound to measure blood flow on patients with chest compression cardiopulmonary resuscitation (CPR), and to find out a real-time, noninvasive hemodynamic evaluation method.

Methods: A prospective study was conducted. All adult patients undergoing CPR admitted to Department of Emergency and intensive care unit (ICU) of Zhengzhou People's Hospital from May 2016 to November 2018 were enrolled. Read More

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http://dx.doi.org/10.3760/cma.j.issn.2095-4352.2019.03.010DOI Listing
March 2019
7 Reads

Transcranial Impedance Changes during Sleep: A Rheoencephalography Study.

IEEE J Transl Eng Health Med 2019 11;7:2700107. Epub 2019 Feb 11.

United Neuroscience Inc.DublinIreland.

Objective: To demonstrate the utility of rheoencephalography (REG) for measuring cerebral blood flow and fluid dynamics during different stages of sleep.

Methods: Anteroposterior cranial electrical impedance was measured with concurrent polysomnography in a group of healthy subjects during sleep. Transcranial electrical impedance was characterized by measuring the peak-to-trough and envelope of the filtered pulsative REG signal as well as its frequency. Read More

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http://dx.doi.org/10.1109/JTEHM.2019.2898193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404797PMC
February 2019
6 Reads

Color Doppler imaging of ocular hemodynamic changes in patients with rheumatoid arthritis unrelated to disease activity.

Rheumatol Int 2019 Jun 12;39(6):1001-1006. Epub 2019 Mar 12.

Department of Ophthalmology, Yildirim Beyazit University Faculty of Medicine, Ankara, Turkey.

We aimed to investigate how orbital blood flow rates in patients with rheumatoid arthritis (RA) are affected by the active and remission phase of the disease. This prospective study included a total of 56 patients with RA (study group) and 24 control individuals (control group). All RA patients were divided into two groups, as active (Group 1) and remission (Group 2) according to the disease activity index (DAS 28) score. Read More

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http://dx.doi.org/10.1007/s00296-019-04275-yDOI Listing
June 2019
27 Reads

Phantom Validation of DCE-MRI Magnitude and Phase-Based Vascular Input Function Measurements.

Tomography 2019 03;5(1):77-89

TECHNA Institute, University Health Network, Toronto, ON, Canada.

Accurate, patient-specific measurement of arterial input functions (AIF) may improve model-based analysis of vascular permeability. This study investigated factors affecting AIF measurements from magnetic resonance imaging (MRI) magnitude (AIF) and phase (AIF) signals, and compared them against computed tomography (CT) (AIF), under controlled conditions relevant to clinical protocols using a multimodality flow phantom. The flow phantom was applied at flip angles of 20° and 30°, flow rates (3-7. Read More

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http://dx.doi.org/10.18383/j.tom.2019.00001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403037PMC
March 2019
7 Reads

Study of some pulmonary function tests in Egyptian children with end-stage renal disease under regular hemodialysis in correlation with dialysis duration.

Saudi J Kidney Dis Transpl 2019 Jan-Feb;30(1):119-128

Department of Pediatrics, Faculty of Medicine, Tanta University, Tanta City, Gharbia Governate, Egypt.

Pulmonary function tests can differentiate between obstructive and restrictive lung diseases and assess the severity of the disease in children. The aim of work was to study pulmonary function tests in children with end-stage renal disease (ESRD) undergoing hemodialysis (HD) and its correlation with dialysis duration. This study was conducted on 40 patients with ESRD on regular HD for at least six months selected from the Pediatric Nephrology unit of Pediatric Department of Tanta university hospital and 40 healthy children as a control group. Read More

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May 2020
8 Reads

Evaluation of resistive index of the prostate and bladder sonomorphologic parameters as replacements for urodynamics to predict bladder outlet obstruction in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia.

Low Urin Tract Symptoms 2019 May 22;11(3):163-168. Epub 2019 Feb 22.

Department of Radiodiagnosis, King George's Medical University, Lucknow, India.

Objective: This study investigated whether the resistive index (RI) of prostate and bladder sonomorphologic parameters (total prostate volume [TPV], detrusor wall thickness [DWT], intraprostatic protrusion [IPP]) can be used instead of urodynamic studies (UDS) to predict bladder outlet obstruction (BOO) in benign prostatic hyperplasia (BPH) with lower urinary tract symptoms (LUTS).

Methods: Men aged ≥50 years with clinical BPH/LUTS were prospectively enrolled included. Basic evaluations, measurement of sonomorphologic parameters, and UDS were performed in accordance with the International Continence Society's Good Urodynamics Practices protocol. Read More

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http://dx.doi.org/10.1111/luts.12256DOI Listing
May 2019
11 Reads
0.543 Impact Factor

Validation of the disposable T-piece resuscitator (Neo-Tee): a bench study.

Arch Dis Child Fetal Neonatal Ed 2019 Nov 19;104(6):F594-F597. Epub 2019 Feb 19.

Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Objective: The Neo-Tee Infant T-piece resuscitator is a disposable T-piece resuscitator. The aim of this bench study was to assess the accuracy of the Neo-Tee using a measurement set-up and settings mimicking clinical practice.

Study Design: Nine Neo-Tee devices were tested using a face mask interface and a manikin. Read More

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http://dx.doi.org/10.1136/archdischild-2018-315298DOI Listing
November 2019
27 Reads

Aortic Pulsatility Propagates Intracranially and Correlates with Dilated Perivascular Spaces and Small Vessel Compliance.

J Stroke Cerebrovasc Dis 2019 May 13;28(5):1252-1260. Epub 2019 Feb 13.

Salford Royal NHS Foundation Trust, Salford, United Kingdom; Wolfson Molecular Imaging Centre, School of Medicine, University of Manchester, Greater Manchester, United Kingdom.

Introduction: To test the hypotheses that changes in the aortic pulse-wave produced by arterial stiffening are (1) propagated into cerebral small vessels, (2) associated with reduced compliance of small cerebral arterial vessels, and (3) associated with the presence of dilated perivascular spaces (PVS).

Methods: Fifteen volunteers and 19 patients with late-onset depression (LOD) were prospectively recruited, of which 6 fulfilled the criteria for treatment-resistant depression (TRD). Aortic pulse-wave velocity (PWV) was determined using Carotid-Femoral Doppler. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.01.020DOI Listing
May 2019
13 Reads

A simple method of transport parameter estimation for slug injecting tracer tests in porous media.

Sci Total Environ 2018 Dec 13;644:1536-1546. Epub 2018 Jul 13.

Guangdong Provincial Key Laboratory of Soil and Groundwater Pollution Control, School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, PR China; State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control, School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, PR China.

Slug (instantaneous injection) tracer tests can be used effectively to determinate solute transport parameters in porous media such as pore velocities and dispersivities, which are usually estimated with curve-fitting methods. This study proposes a simple method to estimate conservative and reactive solute transport parameters in one-, two- and three- dimensional domains with uniform flow fields based on peak times of slug tracer tests. This method requires fewer measured data than traditional curve-fitting methods. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.06.330DOI Listing
December 2018
5 Reads

Impact of frit dispersion on gradient performance in high-throughput liquid chromatography.

J Chromatogr A 2019 Apr 11;1591:110-119. Epub 2019 Jan 11.

Waters Corporation, 34 Maple Street, Milford, MA 01757, USA.

The impact of porous frits (2.1 mm i.d. Read More

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http://dx.doi.org/10.1016/j.chroma.2019.01.021DOI Listing
April 2019
12 Reads

Determination of a astragaloside IV derivative LS-102 in plasma by ultra-performance liquid chromatography-tandem mass spectrometry in dog plasma and its application in a pharmacokinetic study.

Phytomedicine 2019 Feb 5;53:243-251. Epub 2018 Sep 5.

Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China. Electronic address:

Background: Astragalosidic acid (LS-102) is a new water-soluble derivative of astragaloside IV - a major effective component isolated from the Chinese herb Astragali Radix. Our previous study showed that LS-102 exhibited potent cardiovascular activity.

Purpose: The objective of this study was to investigate the pharmacokinetic properties of LS-102 after single-dose, oral administration in beagle dogs by developing and validating an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09447113183030
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http://dx.doi.org/10.1016/j.phymed.2018.09.019DOI Listing
February 2019
21 Reads
3.126 Impact Factor

Pulse sequence considerations for quantification of pyruvate-to-lactate conversion k in hyperpolarized C imaging.

NMR Biomed 2019 03 21;32(3):e4052. Epub 2019 Jan 21.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.

Hyperpolarized C MRI takes advantage of the unprecedented 50 000-fold signal-to-noise ratio enhancement to interrogate cancer metabolism in patients and animals. It can measure the pyruvate-to-lactate conversion rate, k , a metabolic biomarker of cancer aggressiveness and progression. Therefore, it is crucial to evaluate k reliably. Read More

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http://dx.doi.org/10.1002/nbm.4052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380928PMC
March 2019
26 Reads

The influence of posture on parasternal intercostal muscle activity in healthy young adults.

Physiol Meas 2019 02 1;40(1):01NT03. Epub 2019 Feb 1.

Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, King's College London, London, United Kingdom. Equal contribution to the study.

Objective: Parasternal intercostal muscle electromyography (EMGpara) has been used as an index of respiratory load in health and disease. While reference values are available, such data have been obtained with subjects in the seated position only. The objective of the current study was to determine the influence of posture on measurements of EMGpara. Read More

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http://dx.doi.org/10.1088/1361-6579/aafefdDOI Listing
February 2019
11 Reads

Hantzsch pre-column derivatization for simultaneous determination of alendronate sodium and its pharmacopoeial related impurity: Comparative study with synchronous fluorometry using fluorescamine.

J Food Drug Anal 2019 01 18;27(1):208-220. Epub 2018 Jun 18.

Faculty of Pharmacy, Department of Pharmaceutical Analytical Chemistry, University of Alexandria - El-Messalah, Alexandria 2152, Egypt. Electronic address:

High performance liquid chromatographic (HPLC) method with a pre-column derivatization based on Hantzsch condensation reaction was applied for simultaneous determination of alendronate sodium (ALN) and its main related impurity, 4-Aminobutanoic acid (ABA) at its pharmacopeial limit. The separation of colored condensation products of ALN and ABA were achieved on Agilent Zobrax Eclipse SB-C18 analytical column (250 × 4.6 mm, 5 μm) using a mobile phase composed of acetonitrile-0. Read More

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http://dx.doi.org/10.1016/j.jfda.2018.05.009DOI Listing
January 2019
8 Reads
0.395 Impact Factor

Performance Characteristics of the Digital Biograph Vision PET/CT System.

J Nucl Med 2019 07 10;60(7):1031-1036. Epub 2019 Jan 10.

Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

This study evaluated the performance of the Biograph Vision digital PET/CT system according to the NEMA NU 2-2012 standard (published by the National Electrical Manufacturers Association [NEMA]) to allow for a reliable, reproducible, and intersystem-comparable performance measurement. The new digital PET/CT system features silicon photomultiplier-based detectors with 3.2-mm lutetium oxyorthosilicate crystals and full coverage of the scintillator area. Read More

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http://jnm.snmjournals.org/lookup/doi/10.2967/jnumed.118.215
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http://dx.doi.org/10.2967/jnumed.118.215418DOI Listing
July 2019
58 Reads

Growth of perovskite nanocrystals in poly-tetra fluoroethylene based microsystem: on-line and off-line measurements.

Nanotechnology 2019 Apr 10;30(14):145602. Epub 2019 Jan 10.

Key Laboratory of Pressure Systems and Safety (MOE), School of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai 200237, People's Republic of China.

Cesium lead halide perovskite nanocrystals are photoelectric nanomaterials that have potential applications in a variety of areas due to their excellent photoelectric and tunable photo luminescent properties. In this work, we investigate the synergetic effects of reaction temperature, reaction-capillary length and flow rate on the growth kinetics of perovskite nanocrystals in a PTFE-based microsystem and the photoluminescence characteristics of the perovskite nanocrystals both on-line and off-line. The on-line measurement finds that increasing the reaction temperature leads to the increase of the wavelength of the PL emission peak of the synthesized nanocrystals and reduces the average size of the perovskite nanocrystals synthesized in long reaction-capillaries. Read More

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http://iopscience.iop.org/article/10.1088/1361-6528/aafd3b
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http://dx.doi.org/10.1088/1361-6528/aafd3bDOI Listing
April 2019
12 Reads

The impact of lung function case-finding tests on smoking behaviour: A nested randomised trial within a case-finding cohort.

Health Sci Rep 2018 Jun 18;1(6):e41. Epub 2018 May 18.

Institute of Health and Society Newcastle University Newcastle upon Tyne UK.

Rationale Aims And Objectives: Increasing awareness of people's lung health through the use of lung function tests or symptom-based questionnaires is a potential method to aid smoking cessation. We investigated the impact of case-finding lung function tests for chronic obstructive pulmonary disease on smoking behaviour.

Methods: Our trial used a novel waiting list randomised controlled trial design, nested within a case-finding cohort study. Read More

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http://doi.wiley.com/10.1002/hsr2.41
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http://dx.doi.org/10.1002/hsr2.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266471PMC
June 2018
28 Reads

Vortex Whistle and Smart Phone Application for Peak Flow Recordings in Asthmatic Children: A Feasibility Study.

Telemed J E Health 2019 11 20;25(11):1077-1082. Epub 2018 Dec 20.

Department of Pediatrics, Stavanger University Hospital, Stavanger, Norway.

Blowfish Read More

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https://www.liebertpub.com/doi/10.1089/tmj.2018.0270
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http://dx.doi.org/10.1089/tmj.2018.0270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842893PMC
November 2019
9 Reads

Design and Implementation of Respiration Rate Measurement System Using an Information Filter on an Embedded Device.

Sensors (Basel) 2018 Nov 30;18(12). Epub 2018 Nov 30.

Robotics Group, Korea Institute of Industrial Technology, Gyeonggi-do, Ansan-si 15588, Korea.

In this work, an algorithm was developed to measure respiration rate for an embedded device that can be used by a field robot for relief operations. With this algorithm, the rate measurement was calculated based on direct influences of respiratory-induced intensity variation (RIIV) on blood flow in cardiovascular pathways. For this, a photoplethysmogram (PPG) sensor was used to determine changes in heartbeat frequencies. Read More

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http://dx.doi.org/10.3390/s18124208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308642PMC
November 2018
12 Reads

Leachate generation rate modeling using artificial intelligence algorithms aided by input optimization method for an MSW landfill.

Environ Sci Pollut Res Int 2019 Feb 3;26(4):3368-3381. Epub 2018 Dec 3.

Civil Engineering Department, University of Malaya, 50603, Kuala Lumpur, Malaysia.

Leachate is one of the main surface water pollution sources in Selangor State (SS), Malaysia. The prediction of leachate amounts is elementary in sustainable waste management and leachate treatment processes, before discharging to surrounding environment. In developing countries, the accurate evaluation of leachate generation rates has often considered a challenge due to the lack of reliable data and high measurement costs. Read More

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http://link.springer.com/10.1007/s11356-018-3749-5
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http://dx.doi.org/10.1007/s11356-018-3749-5DOI Listing
February 2019
8 Reads

Study of the column efficiency using gradient elution based on Van Deemter plots.

J Chromatogr A 2019 Jan 22;1584:126-134. Epub 2018 Nov 22.

Departament de Química Analítica, Universitat de València, c/Dr. Moliner 50, 46100 Burjassot, Spain.

Performance of chromatographic columns is of major importance in the development of more efficient separation methods. So far, a common practice is to study the column behavior in isocratic elution by modifying the flow rate and fitting the theoretical plate height values versus the mobile phase linear velocity, according to the Van Deemter equation. In this work, an approach is presented to extend the measurement of efficiency to linear gradient elution, where the mean retention factor is kept constant at each assayed flow. Read More

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http://dx.doi.org/10.1016/j.chroma.2018.11.042DOI Listing
January 2019
7 Reads

Assessment of Respiratory Symptoms and Pulmonary Function Status among Workers of Flour Mills in Addis Ababa, Ethiopia: Comparative Cross-Sectional Study.

Pulm Med 2018 24;2018:9521297. Epub 2018 Oct 24.

Addis Ababa University College of Medicine and Health Sciences, Department of Physiology, Addis Ababa, Ethiopia.

Background: Flour dust in the respiratory tract affects lung function. Flour dust is a heterogeneous organic substance which can have a tendency to cause respiratory ailments. There is growing consensus on the deleterious effects of flour dust on respiratory symptoms and lung performance of flour mill workers. Read More

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http://dx.doi.org/10.1155/2018/9521297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220375PMC
January 2019
10 Reads

Temperature of water ingested before exercise alters the onset of physiological heat loss responses.

Am J Physiol Regul Integr Comp Physiol 2019 01 7;316(1):R13-R20. Epub 2018 Nov 7.

Thermal Ergonomics Laboratory, Exercise and Sport Science, Faculty of Health Sciences, University of Sydney , Sydney, New South Wales , Australia.

This study sought to determine whether the temperature of water ingested before exercise alters the onset threshold and subsequent thermosensitivity of local vasomotor and sudomotor responses after exercise begins. Twenty men [24 (SD 4) yr of age, 75.8 (SD 8. Read More

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https://www.physiology.org/doi/10.1152/ajpregu.00028.2018
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http://dx.doi.org/10.1152/ajpregu.00028.2018DOI Listing
January 2019
26 Reads

Industrial radiotracer application in flow rate measurement and flowmeter calibration using Tc and Au nanoparticles radioisotope.

Appl Radiat Isot 2019 Jan 12;143:24-28. Epub 2018 Oct 12.

Plant Assessment Technology Group, Malaysian Nuclear Agency, 43000 Kajang, Malaysia. Electronic address:

The flow rate or fluid velocity measurement is important to maintain fluid flow quality performance in the systems. This study focuses on determination of volumetric flow rate measurement and to calibrate the conventional flowmeter using industrial radiotracer approach in quadrilateral gas-liquid bubble column reactor. In this work, two different radioisotopes which emit γ-ray have been chosen as radioactive tracer which is Tc produced from Mo/Tc radioisotope generator and Au nanoparticle form neutron activation at research nuclear reactor TRIGA Mark II. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09698043173148
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http://dx.doi.org/10.1016/j.apradiso.2018.10.008DOI Listing
January 2019
52 Reads

End tidal carbon dioxide monitoring in acute asthma: a prospective pilot study in emergency department patients.

Eur J Emerg Med 2019 Dec;26(6):412-416

Emergency Department Lariboisière Hospital, AP-HP, University Paris VII René Diderot.

The peak expiratory flow rate (PEFR) is the gold standard for monitoring asthmatic patients. However, its measurement requires understanding and active participation. End tidal carbon dioxide (EtCO2) may be considered an accurate surrogate for PaCO2, a severity marker in acute asthma. Read More

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http://dx.doi.org/10.1097/MEJ.0000000000000581DOI Listing
December 2019
9 Reads