6,323 results match your criteria Pathology[Journal]


Nonfasting versus fasting lipid profile for cardiovascular risk prediction.

Pathology 2018 Dec 3. Epub 2018 Dec 3.

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

Before 2009 essentially all societies, guidelines, and statements required fasting before measuring a lipid profile for cardiovascular risk prediction. This was mainly due to the increase seen in triglycerides during a fat tolerance test. However, individuals eat much less fat during a normal day and nonfasting triglycerides have been shown to be superior to fasting in predicting cardiovascular risk. Read More

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December 2018

PCSK9: from biology to clinical applications.

Pathology 2018 Dec 3. Epub 2018 Dec 3.

Laboratoire Inserm UMR 1188 DéTROI, Université de La Réunion, Sainte-Clotilde, France. Electronic address:

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a crucial protein governing the circulating levels of low density lipoprotein-cholesterol (LDL-C), by virtue of its pivotal role in the degradation of the LDL receptor (LDLR). In the last 15 years, in vitro and in vivo studies have allowed our understanding of the physiological role of PCSK9. In the current report, we review the key studies that have established the mode of action of PCSK9, leading to the development of PCSK9 inhibitors for clinical use. Read More

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December 2018

Digital pathology: semper ad meliora.

Authors:
Simone L Van Es

Pathology 2018 Dec 3. Epub 2018 Dec 3.

Department of Pathology, School of Medical Sciences, UNSW, Sydney, NSW, Australia. Electronic address:

This review is an evidence-based summary of digital pathology: past, present and future. It discusses digital surgical pathology and the cytopathology digitisation challenge as well as the performance of digital histopathology and cytopathology as a diagnostic tool, particularly in contrast to user perceptions. Time and cost efficiency of digital pathology, learning curves, education and quality assurance, with the importance of validation of systems, is emphasised. Read More

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December 2018

Diet, exercise and weight loss and dyslipidaemia.

Authors:
Peter M Clifton

Pathology 2018 Dec 7. Epub 2018 Dec 7.

Alliance for Research in Exercise, Nutrition and Activity (ARENA), Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA, Australia. Electronic address:

There is a large amount of controversy relating dietary fat intake and coronary artery disease. It has been strongly suggested that saturated fat is not harmful and that polyunsaturated fat is either not beneficial or even harmful. Given that dietary lipids and fibre can influence serum lipids which are strongly linked to the risk of coronary artery disease I have reviewed recent evidence linking diet and serum lipids to confirm a diet-heart disease link. Read More

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December 2018

HTLV-1 is rare in Far North Queensland despite a significant burden of classically associated diseases.

Pathology 2018 Nov 28. Epub 2018 Nov 28.

Department of Medicine, Cairns Hospital, Cairns, Qld, Australia; The Kirby Institute, University of New South Wales, Kensington, NSW, Australia.

Human T-lymphotropic virus type 1 (HTLV-1) is hyperendemic amongst Indigenous Australians living in Central Australia. The epidemiology of the disease is poorly defined in other parts of Australia, despite a high prevalence of classically associated conditions. All HTLV-1 serology tests requested through public health facilities in Far North Queensland (FNQ) from January 1999 to December 2016 were reviewed. Read More

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November 2018

Lower number of 5-hydroxymethylcytosine-expressing cells in plasma cell myeloma than in reactive plasma cell hyperplasia: a useful immunohistochemical approach for identification of neoplastic plasma cells.

Pathology 2018 Nov 28. Epub 2018 Nov 28.

Department of Pathology, Shinshu University School of Medicine, Matsumoto, Japan. Electronic address:

Plasma cell myeloma (PCM) is a haematological malignancy defined by aberrant proliferation of plasma cells in the bone marrow. For the diagnosis of PCM, immunostaining of light chains or surface marker analyses by flow cytometry is needed but sometimes difficult. Aberrant methylation at the carbon-5 position of cytosine results in 5-methylcytosine (5-mC), which is a well-known epigenetic hallmark of cancer in mammals. Read More

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November 2018
1 Read

Mismatch repair deficiency is implicated in carcinoma arising from ovarian teratoma.

Pathology 2018 Nov 27. Epub 2018 Nov 27.

Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Hong Kong. Electronic address:

Malignant transformation of benign mature ovarian teratoma can result in a wide spectrum of cancer, including a variety of carcinoma, sarcoma, or melanoma. The role of mismatch repair defects in such malignant transformation is still elusive. In view of current immunotherapy, the role of mismatch repair deficiency can have significant implications on therapeutic strategy. Read More

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November 2018
4 Reads

MMP-9-1562 C/T single nucleotide polymorphism associates with increased MMP-9 level and activity during papillary thyroid carcinoma progression.

Pathology 2018 Nov 26. Epub 2018 Nov 26.

Institute for the Application of Nuclear Energy-INEP, University of Belgrade, Belgrade, Serbia. Electronic address:

Papillary thyroid carcinoma (PTC), a common form of thyroid malignancy, displays significant variations in clinical features and outcome. The malignant transformation of the thyroid is driven by altered expression of many matrix-modulating enzymes, including matrix metalloproteinase-9 (MMP-9). A single nucleotide polymorphism in its promotor (-1562 C/T) is suspected to cause overexpression of MMP-9, which in turn contributes to development of a tumour unfavourable phenotype. Read More

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November 2018

Maternally expressed, paternally imprinted, embryonic non-coding RNA are expressed in osteosarcoma, Ewing sarcoma and spindle cell sarcoma.

Pathology 2018 Nov 26. Epub 2018 Nov 26.

Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, United Kingdom; Department of Clinical Biochemistry, Norfolk and Norwich University Hospital, Norwich Research Park, Norwich, United Kingdom. Electronic address:

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November 2018

MMR protein immunohistochemistry and microsatellite instability in gastric cancers.

Pathology 2018 Nov 26. Epub 2018 Nov 26.

Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. Electronic address:

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November 2018

A high seroprevalence of human herpesvirus type 8 already present in patients with chronic hepatitis before the development of cirrhosis.

Pathology 2018 Nov 26. Epub 2018 Nov 26.

School of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Clinical Pathology, Buddhist Dalin Tzu Chi Hospital, Chiayi County, Taiwan; Department of Anatomic Pathology, Buddhist Dalin Tzu Chi Hospital, Chiayi County, Taiwan. Electronic address:

A high seroprevalence of human herpesvirus type 8 (HHV-8) in mild cirrhotics is significantly associated with hepatitis activity. Cirrhosis is always derived from chronic hepatitis. We aimed to evaluate the prevalence of HHV-8 infection in patients with chronic hepatitis. Read More

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November 2018
4 Reads

Primary anorectal melanoma: clinical, immunohistology and DNA analysis of 43 cases.

Pathology 2018 Nov 26. Epub 2018 Nov 26.

Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; Sydney Medical School, The University of Sydney, Sydney, Australia. Electronic address:

Primary melanoma involving the anorectal region is rare, accounting for <1% of all melanomas in most Western countries. It characteristically presents at an advanced clinical stage and is associated with poor clinical outcomes. Preliminary reports suggest that response rates to immunotherapies in patients with advanced stage mucosal melanoma are much lower than in cutaneous (or acral) melanoma patients but reasons for this are unclear. Read More

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November 2018
4 Reads

Cost-effective implementation of a custom MALDI-TOF library for the identification of South Australian Nocardia isolates.

Pathology 2018 Dec 25;50(7):753-757. Epub 2018 Oct 25.

SA Pathology, Department of Microbiology and Infectious Diseases, Adelaide, SA, Australia.

Mass spectrometry plays a significant role in the routine identification of micro-organisms and provides the ability to incorporate newly found pathogens into the database in a cost-effective fashion. This work aims to highlight the role of mass spectrometry through improved identification of Nocardia species in a diagnostic clinical microbiology laboratory. Prior to this study we constructed a custom in-house matrix-assisted laser desorption ionisation-time of flight (MALDI-TOF) library for Nocardia isolates consisting of isolates identified to the species level. Read More

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December 2018

Blastic plasmacytoid dendritic cell neoplasm with immunoblastoid morphology and MYC rearrangement and overexpression.

Pathology 2018 Nov 24. Epub 2018 Nov 24.

Pathology Project for Molecular Targets, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan; Division of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.

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November 2018

Chronic kidney cortical damage is associated with baseline kidney function and albuminuria in patients managed with radical nephrectomy for kidney tumours.

Pathology 2018 Nov 23. Epub 2018 Nov 23.

Princess Alexandra Hospital, Brisbane, Qld, Australia; Centre for Kidney Disease Research, University of Queensland, Brisbane, Qld, Australia; Translational Research Institute, Brisbane, Qld, Australia.

This study evaluated the relationship between histological markers of chronic kidney damage in patients undergoing radical nephrectomy for kidney tumours and preoperative kidney function, degree of albuminuria, and changes in glomerular volume. A schema to grade chronic kidney damage could be used to identify patients at risk of developing CKD following nephrectomy. Non-neoplastic cortical tissue was sourced from 150 patients undergoing radical nephrectomy for suspected kidney cancer. Read More

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November 2018
11 Reads

Rhabdomyosarcoma with FUS re-arrangement: additional case in support of a novel subtype.

Pathology 2018 Nov 23. Epub 2018 Nov 23.

Department of Anatomical Pathology, PathWest, QEII Medical Centre, Nedlands, WA, Australia.

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November 2018

Dataset for the reporting of prostate carcinoma in core needle biopsy and transurethral resection and enucleation specimens: recommendations from the International Collaboration on Cancer Reporting (ICCR).

Pathology 2018 Nov 23. Epub 2018 Nov 23.

Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.

The International Collaboration on Cancer Reporting (ICCR) is a project which issues datasets and guidelines for international standardisation of cancer reporting. This review summarises the required and recommended elements of the datasets for prostate core needle biopsies and transurethral resection (TURP) and enucleation specimens of the prostate. To obtain as much information as possible from needle biopsies there should be only one core in each specimen jar with the exception of saturation biopsies. Read More

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November 2018
2.188 Impact Factor

High reproducibility is attainable in assessing histoprognostic parameters of pT1 colorectal cancer using routine histopathology slides and immunohistochemistry analyses.

Pathology 2018 Nov 23. Epub 2018 Nov 23.

CHRU Brest, Service d'Anatomie et Cytologie Pathologiques, Brest, France; Inserm U1053 BaRITOn, Bordeaux, France. Electronic address:

Assessment of the risk of lymph node invasion and tumour recurrence is critical to determine whether additional surgery is required in patients with endoscopically-removed pT1 colorectal cancer (CRC). A reproducible assessment of this risk of recurrence based on histopathological parameters is crucial for relevant therapeutic decisions. The inter-observer reproducibility of these parameters was the subject of our study. Read More

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November 2018
1 Read

Ectopic cervical well differentiated thymic carcinoma: report of a diagnostically challenging rare case.

Pathology 2018 Nov 23. Epub 2018 Nov 23.

Department of Pathology, National University Hospital, Singapore. Electronic address:

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November 2018
1 Read

Overexpression of CDK7 is associated with unfavourable prognosis in oral squamous cell carcinoma.

Pathology 2018 Nov 22. Epub 2018 Nov 22.

Department of Oral and Maxillofacial Surgery, Affiliated Stomatological Hospital, Nanjing Medical University, Jiangsu, China. Electronic address:

Increased expression of cyclin-dependent kinase 7 (CDK7), an ubiquitous kinase associated with cell cycle and transcription, contributes to human tumourigenesis and associates with patients' prognosis. In the present study, we sought to investigate the expression pattern of CDK7 and its clinicopathological significance in primary oral squamous cell carcinoma (OSCC). The expression of CDK7 mRNA in OSCC was determined by data mining and interrogation using the Oncomine database. Read More

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November 2018
2.188 Impact Factor

FDG-PET/CT findings, the vital clue to rare diagnosis of herpes simplex virus lymphadenitis simulating Richter transformation.

Pathology 2018 Nov 22. Epub 2018 Nov 22.

Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Vic, Australia; Epworth Healthcare, Melbourne, Vic, Australia; Department of Haematology, Peter MacCallum Cancer Centre, Melbourne, Vic, Australia.

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November 2018

Uterine intravascular adenomyomatosis: a bizarre hybrid lesion?

Pathology 2018 Nov 22. Epub 2018 Nov 22.

Douglass Hanly Moir Pathology, Macquarie Park, NSW, Australia. Electronic address:

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November 2018
1 Read

Analysis of chromosome 12p over-representation and clinicopathological features in mediastinal teratomas.

Pathology 2018 Nov 20. Epub 2018 Nov 20.

Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Teratomas show diverse biologic behaviour and prognosis as well as variable histological features. Importantly, post-pubertal testicular teratomas composed of mature components have a potential for malignant behaviour, in contrast to ovarian dermoid cysts and pre-pubertal testicular teratomas which are considered almost always benign. On the other hand, the biological behaviour and histogenesis of extragonadal teratomas are still not fully elucidated. Read More

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November 2018
5 Reads

Human telomerase reverse transcriptase protein expression predicts tumour aggressiveness and survival in patients with clear cell renal cell carcinoma.

Pathology 2018 Nov 19. Epub 2018 Nov 19.

Oncopathology Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran; Hasheminejad Kidney Center, Iran University of Medical Sciences, Tehran, Iran.

Human telomerase reverse transcriptase (hTERT) is an active component of telomerase and responsible for its catalytic activity, associated with cell proliferation and differentiation. For the first time, the present study was conducted to evaluate the expression and prognostic significance of hTERT in different histological subtypes of renal cell carcinoma (RCC). Expression of hTERT was examined in 176 well-defined renal tumour samples including clear cell RCCs (ccRCCs), papillary and chromophobe RCCs using immunohistochemistry on tissue microarrays. Read More

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November 2018
4 Reads

First report of homocystinuria-megaloblastic anaemia, cobalamin E complementation type, in an Indian child.

Pathology 2018 Nov 19. Epub 2018 Nov 19.

Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Electronic address:

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November 2018
2 Reads
2.188 Impact Factor

Parasitic nodules of thyroid: some insights into the origin and early evolution.

Authors:
Andrey Bychkov

Pathology 2018 Nov 16. Epub 2018 Nov 16.

Department of Pathology, Kameda Medical Center, Kamogawa, Chiba, Japan; Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Electronic address:

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November 2018

Detection of OXA-carbapenemase-producing Enterobacteriaceae with chromID CARBA SMART screening plate.

Pathology 2018 Nov 16. Epub 2018 Nov 16.

Department of Laboratory Medicine, National University Hospital, Singapore. Electronic address:

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November 2018

An insight into in vitro susceptibility of non-albicans Candida species from bloodstream infections to echinocandins in a Singapore cohort.

Pathology 2018 Nov 16. Epub 2018 Nov 16.

Department of Laboratory Medicine, Tan Tock Seng Hospital, Singapore. Electronic address:

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November 2018

Intrathecal Methotrexate-Induced Necrotizing Myelopathy: A Case Report and Review of Histologic Features.

Clin Med Insights Pathol 2018 4;11:1179555718809071. Epub 2018 Nov 4.

Department of Pathology and Laboratory Medicine, UT Health San Antonio, San Antonio, TX, USA.

Central nervous system (CNS) relapse of acute lymphoblastic leukemia (ALL) is associated with a poor prognosis. However, prophylactic measures, including intrathecal (IT) methotrexate, reduce the incidence of CNS relapse in these patients considerably. Unfortunately, IT methotrexate can cause several neurologic complications, including transverse myelopathy; ie, the development of isolated spinal cord dysfunction over hours or days following the IT infusion of methotrexate, but in the absence of a compressive lesion. Read More

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November 2018
3 Reads

Activity of ceftolozane/tazobactam against a collection of Pseudomonas aeruginosa isolates from bloodstream infections in Australia.

Pathology 2018 Dec 2;50(7):748-752. Epub 2018 Nov 2.

UQ Centre for Clinical Research, The University of Queensland, Brisbane, Qld, Australia.

Pseudomonas aeruginosa is a common pathogen causing nosocomial infection. In particular, bloodstream infection (BSI) is associated with a high rate of morbidity and mortality. Ceftolozane/tazobactam is a new β-lactam/β-lactamase antimicrobial with activity against P. Read More

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December 2018
1 Read

Evaluation of the role of Notch1 expression in hepatic carcinogenesis with clinico-pathological correlation.

Pathology 2018 Dec 30;50(7):730-736. Epub 2018 Oct 30.

Pathology Department, College of Medicine, Mansoura University, Mansoura, Egypt.

The role of Notch pathway in hepatocarcinogenesis is unclear with conflicting results reported from different researchers. This study aimed to investigate the exact role of Notch1 in hepatocarcinogenesis and its influence on survival and to determine the possibility of it being a target therapy. Differential immunohistochemical expression of Notch1 in 100 cases of hepatocellular carcinoma (HCC) and adjacent non-neoplastic liver tissue was performed. Read More

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December 2018

Expression of EpCAM in adenoid cystic carcinoma.

Pathology 2018 Dec 30;50(7):737-741. Epub 2018 Oct 30.

Department of Pathology, Yonsei University College of Medicine, Seoul, South Korea. Electronic address:

The mutational landscape of adenoid cystic carcinoma (ACC) is currently being revealed, but further studies are needed to identify biomarkers as therapeutic targets or prognostic factors of ACC. In this study, we investigated the expression of epithelial cell adhesion molecule (EpCAM) in ACCs. We retrospectively collected 83 cases of surgically resected ACCs. Read More

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December 2018

EBV-positive diffuse large B-cell lymphoma features PD-L1 protein but not mRNA overexpression.

Pathology 2018 Dec 30;50(7):725-729. Epub 2018 Oct 30.

Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College Fudan University, Shanghai, China. Electronic address:

Programmed cell death ligand 1 (PD-L1) is upregulated in various types of haematological malignancies and is associated with immunosuppression. This study aimed to investigate the expression pattern of PD-L1 in Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma (DLBCL). We retrospectively analysed clinicopathological characteristics in 30 cases of EBV-positive DLBCL and immunohistochemically evaluated the level of membrane bound PD-L1 protein. Read More

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December 2018
8 Reads

Health service impact of testing for respiratory pathogens using cartridge-based multiplex array versus molecular batch testing.

Pathology 2018 Dec 30;50(7):758-763. Epub 2018 Oct 30.

Microbiology Department, Royal Melbourne Hospital, Melbourne, Vic, Australia; The University of Melbourne, Melbourne, Vic, Australia; Murdoch Children's Research Institute, Parkville, Vic, Australia.

There is increasing demand for access to rapid microbiological testing, with a view to improving clinical outcomes. The possibility of rapid testing has been facilitated by development of cartridge-based random access molecular technologies that are now widely available. Whether the expense of cartridge-based assays is justified in terms of clinical or laboratory cost savings is controversial. Read More

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December 2018
9 Reads
2.190 Impact Factor

Idiopathic granulomatous mastitis: a 10-year study from a multicentre clinical database.

Pathology 2018 Dec 30;50(7):742-747. Epub 2018 Oct 30.

Department of Surgery, Queen Mary Hospital, Hong Kong; Department of Surgery, The University of Hong Kong, Hong Kong. Electronic address:

Idiopathic granulomatous mastitis (IGM) is an uncommon, chronic inflammatory breast disease with elusive aetiology, simulating malignancy clinically and radiologically. Here we present our 10-year review on a region-wide multicentre IGM database. A retrospective study was performed on a prospectively maintained database from three University affiliated hospitals in Hong Kong and Shenzhen, China. Read More

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December 2018
3 Reads

Neuroendocrine cell proliferations in lungs explanted for fibrotic interstitial lung disease and emphysema.

Pathology 2018 Dec 22;50(7):699-702. Epub 2018 Oct 22.

Department of Pathology, University of Maryland Medical System, Baltimore, MD, United States; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, United States.

Using recently proposed pathological criteria, we determined the incidence of neuroendocrine cell proliferation in a series of explants with lung disease. Cases were defined as NECH (≥3 bronchioles with ≥5 endocrine cells), borderline diffuse neuroendocrine cell hyperplasia (DPNECH) (1-3 tumourlets with or without NECH), and DPNECH (≥3 tumourlets with NECH). Endocrine cells were identified by immunohistochemical staining for synaptophysin. Read More

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December 2018
4 Reads

Atypical finding of meningothelial-like inclusions in cervical lymph nodes.

Pathology 2018 Dec 22;50(7):785-787. Epub 2018 Oct 22.

Sunshine Coast University Hospital, Qld, Australia.

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December 2018

Mycosis fungoides in Taiwan shows a relatively high frequency of large cell transformation and CD56 expression.

Pathology 2018 Dec 20;50(7):718-724. Epub 2018 Oct 20.

Department of Pathology, Chi-Mei Medical Center, Tainan, Taiwan; Department of Pathology, School of Medicine, Taipei Medical University and National Taiwan University, Taipei, Taiwan. Electronic address:

Mycosis fungoides (MF) is an indolent cutaneous T-cell lymphoma and may transform into large cell lymphoma in the disease course. The incidence of MF in Taiwan is lower as compared to that in the West. In this study we aimed to characterise the clinicopathological, immunohistochemical, and genetic features of transformed MF (t-MF) in Taiwan. Read More

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December 2018
8 Reads

Genetic profiling of melanoma in routine diagnostics: assay performance and molecular characteristics in a consecutive series of 274 cases.

Pathology 2018 Dec 20;50(7):703-710. Epub 2018 Oct 20.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany; German Cancer Consortium (DKTK), Partner Site, Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

A deeper understanding of melanoma biology has opened up new avenues for mechanistically informed therapies. However, data on the prevalence of druggable genetic lesions in melanoma are still conflicting and real-world performance data on high-throughput genetic profiling of melanoma cases using formalin fixed, paraffin embedded (FFPE) tissue with variable tumour cellularity and quality are lacking. We retrospectively analysed targeted next-generation sequencing data of 274 consecutive melanoma samples obtained for routine diagnostics between December 2013 and July 2017. Read More

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December 2018

Prostatic adenocarcinoma with aberrant diffuse expression of high molecular weight cytokeratin.

Pathology 2018 Dec 19;50(7):787-789. Epub 2018 Oct 19.

Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA; Department of Oncology, University of Rochester Medical Center, Rochester, NY, USA; Department of Urology, University of Rochester Medical Center, Rochester, NY, USA. Electronic address:

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December 2018

Low additional yield from prolonged culture of urine and differential detection of Actinotignum schaalii in a private laboratory setting.

Pathology 2018 12 11;50(7):766-767. Epub 2018 Oct 11.

Microbiology Department, Douglass Hanly Moir Pathology, Macquarie Park, NSW, Australia.

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December 2018

A new hypoglycaemia pack has revolutionised hypoglycaemia investigations in infants and children.

Authors:
Kay Weng Choy

Pathology 2018 12 9;50(7):769-773. Epub 2018 Oct 9.

Monash Health, Clayton, Vic, Australia. Electronic address:

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December 2018
1 Read

Combined hepatocellular carcinoma and high grade neuroendocrine carcinoma with EWSR1 gene rearrangement.

Pathology 2018 Dec 9;50(7):779-782. Epub 2018 Oct 9.

Department of Pathology, Tan Tock Seng Hospital, Singapore.

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December 2018
1 Read

Adenocarcinoma ex-goblet cell carcinoid of the ascending colon concurrent with conventional adenocarcinoma.

Pathology 2018 Dec 9;50(7):789-792. Epub 2018 Oct 9.

Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Republic of Korea; Department of Surgery, Chonbuk National University Medical School, Jeonju, Republic of Korea.

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December 2018
1 Read

Thrombotic thrombocytopenic purpura associated with Hodgkin lymphoma and non-Hodgkin lymphoma.

Pathology 2018 Dec 9;50(7):776-777. Epub 2018 Oct 9.

Sunshine Coast University Hospital, Birtinya, Qld, Australia.

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December 2018
1 Read

Cutaneous malignant glomus tumours: applicability of currently established malignancy criteria for tumours occurring in the skin.

Pathology 2018 Dec 9;50(7):711-717. Epub 2018 Oct 9.

Department of Dermatopathology, St John's Institute of Dermatology, St Thomas' Hospital, London, United Kingdom.

Glomus tumours (GTs) have traditionally been classified into benign GTs, GTs with uncertain malignant potential and malignant GTs, based on a combination of criteria such as size of the tumour, degree of nuclear atypia and the level of mitotic activity. Several of the proposed grading criteria are difficult, or even impossible to apply for GTs occurring in the skin. The aim of the study was to analyse the applicability of the currently established GT malignancy criteria for tumours occurring in the skin and to establish their prognostic significance. Read More

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December 2018
1 Read

Unexpected histological appearance of breast implant associated fibrous pseudocapsules.

Authors:
Mark J Wilsher

Pathology 2018 Dec 9;50(7):782-785. Epub 2018 Oct 9.

Unilabs IHS, London, United Kingdom. Electronic address:

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December 2018
1 Read