5,312 results match your criteria Patent Foramen Ovale


Percutaneous transcatheter closure of high-risk patent foramen ovale in the elderly.

Heart Vessels 2019 Mar 13. Epub 2019 Mar 13.

Department of Cardiology, Tokushima Red Cross Hospital, 103 Irinokuchi, Komatsushima-cho, Komatsushima, Tokushima, 773-8502, Japan.

The efficacy of percutaneous transcatheter closure for preventing recurrent cerebrovascular events in elderly patients with high-risk patent foramen ovale (PFO) remains unclear, whereas in young patients, it has been shown to effectively prevent the recurrence of embolic stroke. The aim of this study was to investigate the safety and efficacy of percutaneous PFO closure in elderly patients with high-risk PFO. Between September 2012 and October 2018, 14 patients 60 years old with high-risk PFO underwent percutaneous closure to prevent recurrence of cerebrovascular events. Read More

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http://dx.doi.org/10.1007/s00380-019-01379-0DOI Listing

[Patent foramen ovale with a license to kill].

Authors:
B Meier

Med Klin Intensivmed Notfmed 2019 Mar 11. Epub 2019 Mar 11.

Universitätsklinik für Kardiologie, Departement Herz und Gefässe, Inselspital, 3010, Bern, Schweiz.

A patent foramen ovale (PFO) is present in about one of four, and one of its dangerous forms (large or associated with atrial septal aneurysm, Eustachian valve, or Chiari network) in one of twenty people. About 140 years ago, the PFO was shown to have the potential to result in death due to stroke and also myocardial infarction. The described decrease of the prevalence of a PFO with age may be a consequence of this. Read More

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http://dx.doi.org/10.1007/s00063-019-0561-zDOI Listing

Patent Foramen Ovale Closure in 2019.

Interv Cardiol 2019 Feb;14(1):34-41

Department of Cardiology, Royal Papworth Hospital NHS Foundation Trust Cambridge, UK.

Patent foramen ovale (PFO) is a common abnormality affecting between 20% and 34% of the adult population. For most people it is a benign finding; however, in some the PFO can open widely, enabling a paradoxical embolus to transit from the venous to arterial circulation, which is associated with stroke and systemic embolisation. Percutaneous closure of PFO in patients with cryptogenic stroke has been undertaken for a number of years, and a number of purpose-specific septal occluders have been marketed. Read More

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http://dx.doi.org/10.15420/icr.2018.33.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406129PMC
February 2019

[Patent foramen ovale closure: how to choose the right device for the right patient].

G Ital Cardiol (Rome) 2019 Mar;20(3):9-16

Interventistica Cardiologica Strutturale, Dipartimento Cardio-Toraco-Vascolare, AOU Careggi, Firenze.

Percutaneous patent foramen ovale (PFO) closure is an intervention aimed to prevent cardioembolic stroke. It recently proved to be superior to antiplatelet therapy in preventing recurrent strokes in a well-selected population of patients with a previous cryptogenic cerebral ischemic event. A large part of the clinical advantage of PFO transcatheter therapy derives from the very high efficacy and safety of the maneuver. Read More

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http://dx.doi.org/10.1714/3121.31036DOI Listing

[What's new in the management of patients with patent foramen ovale?]

G Ital Cardiol (Rome) 2019 Mar;20(3):4-8

U.O.C. Emodinamica, P.O. San Filippo Neri, ASL Roma 1, Roma.

Patent foramen ovale (PFO) is associated with a number of clinical syndromes in which it plays variable roles that, often, cannot be accurately determined. This situation creates conflicting data and controversial studies. However, in 2017 and 2018, four randomized clinical trials have been published, allowing for the clarification of certain issues pertaining to cryptogenic stroke. Read More

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http://dx.doi.org/10.1714/3121.31035DOI Listing

A Case of Paradoxical Embolism Causing Anterior Spinal Cord Syndrome and Acute Myocardial Infarction Following the Intradiscal Oxygen-Ozone Therapy.

Front Neurol 2019 22;10:137. Epub 2019 Feb 22.

Hunan Clinical Research Center of Cerebrovascular Disease, Changsha, China.

We report a case of a 66-year-old female who burst into flaccid paralysis of the lower extremities, accompanied by loss of pain and temperature sensation below T4 level, during an oxygen-ozone injection for disc herniation. Half an hour later, she suffered from chest pain. Magnetic resonance imaging (MRI) showed long segment hyperintensity in the thoracic spinal cord from T2 to 10 level on sagittal T2-weighted images (T2WI). Read More

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http://dx.doi.org/10.3389/fneur.2019.00137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395432PMC
February 2019

Neither Here nor There: Intracardiac Thrombus in Transit Wedged in a Patent Foramen Ovale.

Mayo Clin Proc 2019 Mar;94(3):547-549

Department of Cardiovascular Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2018.12.031DOI Listing

Is mitral valve disease treated differently in men and women?

Eur J Prev Cardiol 2019 Mar 4:2047487319833307. Epub 2019 Mar 4.

Northwestern University Feinberg School of Medicine, Bluhm Cardiovascular Institute, Chicago, IL, USA.

Purpose: This study was performed to determine if there is a sex-based bias in referral practices, complexity of disease, surgical treatment, or outcomes in patients undergoing mitral valve surgery at our institution.

Methods: Data were collected from the Cardiovascular Research Database of the Clinical Trial Unit of the Bluhm Cardiovascular Institute at Northwestern Memorial Hospital and they were defined according to the Society of Thoracic Surgeons National Database ( www.sts. Read More

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http://dx.doi.org/10.1177/2047487319833307DOI Listing
March 2019
2 Reads

Robotic repair of partial anomalous pulmonary venous connection: the initial experience and technical details.

J Robot Surg 2019 Mar 4. Epub 2019 Mar 4.

Department of Anesthesiology and Reanimation, University of Health Sciences, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.

This study reports our initial experience with robotic-assisted partial anomalous pulmonary venous connection (PAPVC) repair. From May 2013 through September 2018, 20 patients (12 male and 8 female) underwent robotic-assisted repair of a right-sided (n = 19) or a left-sided (n = 1) PAPVC. The mean age was 24. Read More

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http://dx.doi.org/10.1007/s11701-019-00943-0DOI Listing
March 2019
1 Read

Cardioembolic Sources in Patients With Small Single Subcortical Infarcts.

Neurologist 2019 Mar;24(2):56-58

Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Transthoracic echocardiogram (TTE) is widely used as part of the work-up for ischemic stroke. However, the added utility of TTE in the management of small single subcortical infarcts (SSSI) has not been extensively evaluated. Therefore, we aimed to determine the frequency of high-risk and medium-risk cardioembolic sources diagnosed by TTE in SSSI patients, and whether the findings altered clinical management. Read More

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http://dx.doi.org/10.1097/NRL.0000000000000224DOI Listing
March 2019
1 Read

Left Atrial Wall Trauma Causing Intracardiac Thrombus After Device Closure of Patent Foramen Ovale.

Circ Cardiovasc Imaging 2019 Mar;12(3):e008720

Division of Cardiology, Department of Medicine, Ahmanson/UCLA Adult Congenital Heart Disease Center, David Geffen School of Medicine, Los Angeles, CA (A.J.S., J.A.A.).

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http://dx.doi.org/10.1161/CIRCIMAGING.118.008720DOI Listing

Asymptomatic Right Ventricular Hypoplasia in Twin Siblings: A Normal Variant or Cause of Early Mortality?

Case Rep Pediatr 2019 21;2019:6871340. Epub 2019 Jan 21.

Division of Pediatric Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Right ventricular (RV) hypoplasia may develop secondary to pulmonary or tricuspid valve atresia. These patients are usually symptomatic early in life and need prompt intervention. Isolated RV hypoplasia is a rare congenital heart disease. Read More

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http://dx.doi.org/10.1155/2019/6871340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360540PMC
January 2019
1 Read

Provocative maneuvers to improve patent foramen ovale detection: A brief review of the literature.

Echocardiography 2019 Feb 25. Epub 2019 Feb 25.

Department of Cardiovascular Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania.

Patent foramen ovale (PFO) is the most common type of inter-atrial shunt, with prevalence as high as 30%. Detection of PFO has implications in patients with stroke, peripheral embolism, decompression illness, and other conditions. Transesophageal echo (TEE) with saline contrast injection is the current standard for PFO detection, but even with TEE, PFOs are sometimes missed. Read More

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http://dx.doi.org/10.1111/echo.14297DOI Listing
February 2019

Cryptogenic stroke - How to make sense of a non-diagnostic entity.

Authors:
Ursula G Schulz

Maturitas 2019 Apr 11;122:44-50. Epub 2019 Jan 11.

Centre for the Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK. Electronic address:

Secondary preventive strategies in ischaemic stroke depend on the underlying aetiology. However, approximately one-third of ischaemic strokes remain unexplained, or 'cryptogenic'. There is a wide range of possible underlying causes in cryptogenic stroke, and the best approach to secondary prevention of these may differ. Read More

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http://dx.doi.org/10.1016/j.maturitas.2019.01.004DOI Listing

Tricuspid valve dysplasia and a patent foramen ovale resulting in severe tricuspid regurgitation and right-heart dilation in a Red Angus calf.

J Vet Cardiol 2019 Feb 11;21:28-33. Epub 2018 Dec 11.

Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI 53706, USA.

A two-month-old Red Angus heifer calf presented to the University of Wisconsin Veterinary Care for evaluation of suspected severe bronchopneumonia. Pertinent physical exam findings included tachycardia, tachypnea, dyspnea with a significant abdominal component, and cyanotic mucous membranes. On thoracic auscultation, wheezes were present bilaterally, as well as a grade 2/6 right apical systolic murmur. Read More

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http://dx.doi.org/10.1016/j.jvc.2018.10.005DOI Listing
February 2019
1 Read

Closure of patent foramen ovale and "cryptogenic" stroke: What's new, what's next?

Authors:
Jean-Louis Mas

Arch Cardiovasc Dis 2019 Feb 18. Epub 2019 Feb 18.

Inserm 894, Department of Neurology, DHU NeuroVasc Sorbonne Paris-Cité, Paris Descartes University, Hôpital Sainte-Anne, 75674 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.acvd.2019.01.001DOI Listing
February 2019
1 Read

Impact of Discontinuation of Antithrombotic Therapy Following Closure of Patent Foramen Ovale in Patients With Cryptogenic Embolism.

Am J Cardiol 2019 Feb 8. Epub 2019 Feb 8.

Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada; Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada. Electronic address:

No data exist on the optimal duration of antithrombotic therapy (AT) following patent foramen ovale (PFO) closure. We sought to assess the safety of AT discontinuation following PFO closure in patients with a cryptogenic ischemic event. A total of 453 consecutive patients (mean age: 48 ± 13 years, men: 51%) who underwent PFO closure due to a cryptogenic ischemic event were included. Read More

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http://dx.doi.org/10.1016/j.amjcard.2019.01.043DOI Listing
February 2019
1 Read

Cerebrovascular ischemia following ultrasound-guided foam sclerotherapy.

J Vasc Bras 2018 Oct-Dec;17(4):333-336

Universidade do Oeste de Santa Catarina - UNOESC, Joaçaba, SC, Brasil.

Cerebral ischemia is a very rare and harmful complication of ultrasound-guided foam sclerotherapy for treatment of varicose veins. This case describes a documented cerebrovascular ischemia in Broca's area following ultrasound-guided foam sclerotherapy. Less than one hour after intravenous injection of 10 ml of sclerosing foam, an otherwise healthy woman experienced aphasia without any other signs of neurological changes. Read More

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http://dx.doi.org/10.1590/1677-5449.004418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375263PMC
February 2019

Are we there yet with patent foramen ovale closure for secondary prevention in cryptogenic stroke? A systematic review and meta-analysis of randomized trials.

SAGE Open Med 2019 4;7:2050312119828261. Epub 2019 Feb 4.

Department of Cardiovascular Diseases, Mayo Clinic, Phoenix, AZ, USA.

Background: We performed a meta-analysis to evaluate the benefit of patent foramen ovale closure in stroke prevention.

Methods: We searched Medline/PubMed, EMBASE, Web of Science and Cochrane central database for randomized control trials assessing the incidence of recurrent stroke after patent foramen ovale closure when compared to medical therapy. Pooled odds ratio and 95% confidence intervals were calculated using a random effects model. Read More

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http://dx.doi.org/10.1177/2050312119828261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365999PMC
February 2019

Trends in surgical and catheter interventions for isolated congenital shunt lesions in the UK and Ireland.

Heart 2019 Feb 16. Epub 2019 Feb 16.

Paediatric Cardiac Surgery, Birmingham Children's Hospital, Birmingham, UK.

Objective: To evaluate time trends in the use of catheter and surgical procedures, and associated survival in isolated congenital shunt lesions.

Methods: Nationwide, retrospective observational study of the UK National Congenital Heart Disease Audit database from 2000 to 2016. Patients undergoing surgical or catheter procedures for atrial septal defect (including sinus venosus defect), patent foramen ovale, ventricular septal defect and patent arterial duct were included. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-314428DOI Listing
February 2019
2 Reads

Impending Paradoxical Embolism.

Ann Thorac Surg 2019 Feb 11. Epub 2019 Feb 11.

Department of Echocardiograph, Asia Heart Hospital, Wuhan, P.R. China. Electronic address:

Impending paradoxical embolism (IPDE) is the presence of a thrombus in the patent foramen ovale (PFO). Usually, IPDE is diagnosed by echocardiography or an Multislice computer tomography (MSCT) scan and is performed during the evaluation of a patient presenting with suspected pulmonary embolism (PE). We report two patients who presented with IPDE and were successfully treated with cardiac surgery and thrombolytic therapy. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2019.01.011DOI Listing
February 2019
3 Reads

Mixed cerebrovascular disease in an elderly patient with mixed vascular risk factors: a case report.

BMC Neurol 2019 Feb 12;19(1):26. Epub 2019 Feb 12.

Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China.

Background: Mixed cerebrovascular disease is a diagnostic entity that presents with hemorrhagic and ischemic stroke clinically and/or subclinically. Here, we report a patient with mixed vascular risk factors, who presented with multiple intracerebral hemorrhages and a simultaneously occurring cerebral infarction with hemorrhagic transformation.

Case Presentation: A 63-year-old male with no history of trauma or prior neurological disease presented with a sudden onset of weakness in his right limbs, followed by an episode of focal seizure without impaired awareness. Read More

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http://dx.doi.org/10.1186/s12883-019-1248-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371517PMC
February 2019
4 Reads

Can complex mitral valve repair be performed with robotics? An institution's experience utilizing a dedicated team approach in 500 patients.

Eur J Cardiothorac Surg 2019 Feb 11. Epub 2019 Feb 11.

Department of Cardiothoracic Surgery, Division of Cardiac Surgery, NYU Langone Health, New York, NY, USA.

Objectives: The full potential of robotics has not been achieved in terms of addressing the most challenging mitral valve (MV) cases. We outline our technique and report our early results with totally endoscopic robotic MV repair in a wide range of pathologies.

Methods: From May 2011 to August 2017, a dedicated team attempted totally endoscopic robotic MV repair in 500 MV regurgitation patients. Read More

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http://dx.doi.org/10.1093/ejcts/ezz029DOI Listing
February 2019
6 Reads

[Transcatheter closure of patent foramen ovale in patients with cryptogenic stroke].

G Ital Cardiol (Rome) 2019 02;20(2):73-84

Cardiologia Pediatrica e dell'Età Evolutiva, Centro per il Trattamento del Cardiopatico Congenito Adulto, Policlinico S. Orsola-Malpighi, Università degli Studi, Bologna.

Treatment of patients with cryptogenic stroke and a patent foramen ovale (PFO) has always been a matter of discussion. A clear pathogenic relationship is difficult to demonstrate in most cases, also because of the high prevalence of a PFO in the general population (25-30%). Early randomized trials failed to demonstrate a superiority of PFO transcatheter closure with respect to medical therapy alone but more recent data, coming from new randomized trials, strongly suggest that PFO closure associated with antiplatelet therapy is more effective than antiplatelet therapy alone in preventing recurrent stroke, with no increased risk of major adverse cardiovascular events in the follow-up; only a higher incidence of atrial fibrillation has been reported after PFO closure. Read More

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http://dx.doi.org/10.1714/3093.30855DOI Listing
February 2019
1 Read

Amplatzer patent foramen ovale occluder: safety and efficacy.

Expert Rev Med Devices 2019 Mar 18;16(3):173-182. Epub 2019 Feb 18.

a Department of Cardiology , University Hospital of Bern , Bern , Switzerland.

Introduction: The patent foramen ovale (PFO) is a common anatomical variant in humans (prevalence 25%). Most often asymptomatic, it may engender paradoxically embolic strokes, myocardial infarctions, or visceral or peripheral ischemia. It is causatively related to migraine, positional or exertional hypoxemia with dyspnea, diving incidents, high altitude edema, and sleep apnea. Read More

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http://dx.doi.org/10.1080/17434440.2019.1581060DOI Listing
March 2019
7 Reads

Rapid evaluation of acute pulmonary embolism with thromboembolism-in-transit.

J Card Surg 2019 Feb 10. Epub 2019 Feb 10.

Department of Thoracic and Cardiovascular Surgery, Gil Medical Center, Gachon Cardiovascular Research Institute, Gachon University, Incheon, South Korea.

We report a case of thromboembolism-in-transit through a patent foramen ovale that could cause systemic embolism in a patient with pulmonary embolism. An accurate and quick diagnosis by transthoracic echocardiography and computed tomography allowed emergent surgical thromboembolectomy to be performed without complications. Integral diagnostic workup should be performed in case of acute pulmonary thromboembolism whether the patient is hemodynamically stable or not. Read More

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http://dx.doi.org/10.1111/jocs.13992DOI Listing
February 2019
1 Read

Current management aspects in adult congenital heart disease: non-surgical closure of patent foramen ovale.

Cardiovasc Diagn Ther 2018 Dec;8(6):739-753

Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia.

A patent foramen ovale (PFO) is a remnant interatrial communication, best diagnosed with transoesophageal echocardiography (TOE) and bubble study. Although quite common and often asymptomatic, PFO is associated with cryptogenic stroke and migraine. Approximately one-half of patients with a cryptogenic stroke have a PFO, and the dilemma regarding whether or not to proceed with percutaneous device closure, to reduce the risk of future recurrent events due to paradoxical embolism, has been subject to debate for nearly two decades. Read More

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http://dx.doi.org/10.21037/cdt.2018.09.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331369PMC
December 2018
2 Reads

Captured in the act: Thrombus crossing patent-foramen-ovale.

Rev Clin Esp 2019 Feb 4. Epub 2019 Feb 4.

Departamento de Cardiología, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universidad de Barcelona, Barcelona, España.

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http://dx.doi.org/10.1016/j.rce.2018.10.010DOI Listing
February 2019

Patent Foramen Ovale: Story Closed?

J Stroke 2019 Jan 31;21(1):23-30. Epub 2019 Jan 31.

Department of Neurology, Frankfurt Hoechst Hospital, Frankfurt, Germany.

The optimal treatment strategy for secondary prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) has been a matter of controversy for decades. After three randomized trials failed to show a benefit of closure with an excess of complications in the interventional arm, two large recent trials suggest a benefit with regard of preventing further ischemic strokes. With this discrepancy in results it is important to discuss recent trials in detail and evolve an informed clinical approach for daily practice. Read More

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http://dx.doi.org/10.5853/jos.2018.03097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372901PMC
January 2019
1 Read

False-Negative Platelet Factor 4 Antibodies and Serotonin Release Assay and the Utility of Repeat Testing in the Diagnosis of Heparin-Induced Thrombocytopenia and Thrombosis.

Case Rep Hematol 2019 8;2019:1585014. Epub 2019 Jan 8.

Department of Neurointensive Care, Cerebrovascular Center, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA.

Objective: To report a case of false-negative serological tests in the diagnosis of heparin-induced thrombocytopenia (HIT) followed by a brief review of the literature on this topic.

Case Presentation: A 75-year-old Caucasian female patient was admitted with a traumatic right ankle fracture that required open reduction and internal fixation. Despite postoperative subcutaneous heparin chemoprophylaxis, she developed deep vein thrombosis (DVT) and pulmonary embolism (PE) on day 4 and subsequently started on continuous heparin infusion. Read More

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http://dx.doi.org/10.1155/2019/1585014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341253PMC
January 2019
2 Reads

[Paradoxical embolism due to a persistent patent foramen ovale. Report of one case].

Rev Med Chil 2018 Dec;146(10):1210-1214

Unidad de ecocardiografía, Hospital Clinic, Barcelona, España.

Patent Foramen Ovale (PFO) is one of the most frequent congenital defects in adults. Its prevalence in middle-aged adults is close to 25-30% and may cause paradoxical embolic phenomena. We report a 45 years old male admitted for an ischemic stroke with an occlusion of the left terminal internal carotid artery. Read More

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http://dx.doi.org/10.4067/S0034-98872018001001210DOI Listing
December 2018
2 Reads

Closure of foramen ovale triggered by injury to tunnel surfaces of septum primum and secundum.

J Interv Card Electrophysiol 2019 Jan 31. Epub 2019 Jan 31.

Heart & Vascular Institute, Sutter Medical Center, 2800 L Street, Sacramento, CA, 95816, USA.

Introduction: We investigated the feasibility to proactively stimulate subsequent closure of a patent foramen ovale (PFO) by injuring (mechanical trauma or radiofrequency [RF] energy) the opposing surfaces of the septum primum (SP) and septum secundum (SS).

Methods: 1. Mechanical Injury: The interatrial septum of patients who underwent multiple left atrial (LA) ablations over 6 years, where a PFO was used for LA access, were examined. Read More

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http://link.springer.com/10.1007/s10840-019-00510-5
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http://dx.doi.org/10.1007/s10840-019-00510-5DOI Listing
January 2019
5 Reads

Bilateral thalamic stroke in patient with patent foramen ovale and hereditary thrombophilia.

Ter Arkh 2018 Nov;90(11):62-66

Faculty of Medicine, Chair of Internal Medicine №1, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.

Patent foramen ovale and hereditary thrombophilia are both known risk factors for ischemic stroke. Artery of Percheron is a rare anatomical variant in which vast areas of the midbrain and thalamus have a single source of blood supply. This case report presents a 45-years old female patient with bilateral thalamic stroke due to Percheron artery occlusion, with a combination of hereditary thrombophilia and patent foramen ovale as the risk factors. Read More

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http://dx.doi.org/10.26442/terarkh2018901162-66DOI Listing
November 2018

Pulmonary embolism with migrating thrombus through patent foramen ovale: A case for a mixed pharmacological and percutaneous management.

J Cardiol Cases 2019 Jan 27;19(1):19-21. Epub 2018 Sep 27.

Interventional Cardiology Unit, S. Ambrogio Cardio-Thoracic Center, Milan, Italy.

A 61-year-old man, admitted to our hospital for bilateral pulmonary embolism, complicated by right renal ischemia and multiple splenic infarcts due to a mobile thrombus entrapped in a patent foramen ovale, has been successfully treated with apixaban 5 mg twice daily followed by transcatheter patent foramen ovale closure. < Apixaban could be a therapeutic alternative to thrombolysis and surgery in patients with warfarin-resistant thrombus straddling in the patent foramen ovale (PFO). Furthermore, apixaban could be a simple and useful option to manage patients undergoing transcatheter PFO closure. Read More

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http://dx.doi.org/10.1016/j.jccase.2018.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342615PMC
January 2019
1 Read

Sensitivity of contrast-enhanced transthoracic echocardiography for the detection of residual shunts after percutaneous patent foramen ovale closure.

Medicine (Baltimore) 2019 Jan;98(4):e14276

Department of Cardiology, Dalian Municipal Central Hospital affiliated of Dalian Medical University, Dalian, Liaoning, China.

The objective of this study is to investigate the sensitivity of contrast-enhanced transthoracic echocardiography (c-TTE) versus transesophageal echocardiography (TEE) to detect a residual right-to-left shunt (RLS) following a transcatheter patent foramen ovale (PFO) closure.A self-controlled study was conducted in a tertiary referral hospital. 57 patients with PFO who had experienced migraines underwent percutaneous PFO closure. Read More

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http://Insights.ovid.com/crossref?an=00005792-201901250-0008
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http://dx.doi.org/10.1097/MD.0000000000014276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358410PMC
January 2019
11 Reads

Device Closure of the Patent Foramen: The Longer You Look, the More You Like It.

J Am Coll Cardiol 2019 Jan;73(3):288-290

Department of Cardiology, University Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.jacc.2018.10.062DOI Listing
January 2019

Long-Term Follow-Up After Closure of Patent Foramen Ovale in Patients With Cryptogenic Embolism.

J Am Coll Cardiol 2019 Jan;73(3):278-287

Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada; Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada. Electronic address:

Background: Patent foramen ovale (PFO) closure is the gold standard for treating patients with cryptogenic stroke and PFO. However, scarce data exist on the long-term outcomes following PFO closure.

Objectives: The purpose of this study was to determine the long-term (>10 years) clinical outcomes (death, ischemic, hemorrhagic events) following transcatheter PFO closure. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.10.061DOI Listing
January 2019
2 Reads

Prognostic value of the PaO2/FiO2 ratio determined at the end-surgery stage of a double-lung transplantation.

Clin Transplant 2019 Jan 22:e13484. Epub 2019 Jan 22.

Department of Anesthesiology, Hôpital Foch, 92150, Suresnes, France.

Introduction: We evaluated the prognostic role of the arterial oxygen partial pressure / fractional inspired oxygen ratio (PaO2/FiO2 ratio) measured at the end of double-lung transplantation (DLT).

Methods: This was a monocentric cohort study of all consecutive DLT patients between January 1st, 2012 and January 1st, 2016 except patients with pre-operative extracorporeal membrane oxygenation (ECMO), intraoperative cardiopulmonary bypass, post-operative ECMO, large patent foramen ovale, redo transplantation during the study period, and multiorgan transplantation.

Results: 164 patients were included in the study; 45 had a PaO2/FiO2 ratio < 200, 39 a ratio in the range 200-300, and 80 a ratio >300. Read More

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http://dx.doi.org/10.1111/ctr.13484DOI Listing
January 2019
2 Reads

Patent foramen ovale: the known unknowns.

EuroIntervention 2019 Jan;14(13):1350-1352

Tufts University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.4244/EIJV14I13A244DOI Listing
January 2019
3 Reads

Stroke in patients with cardiovascular implantable electronic device infection undergoing transvenous lead removal.

Heart Rhythm 2018 11;15(11):1593-1600

Mayo Clinic Arizona, Phoenix, Arizona. Electronic address:

Background: Stroke can be a devastating complication in patients with cardiovascular implantable electronic device (CIED) infection. Paradoxical septic embolism can occur in the presence of device leads and patent foramen ovale (PFO) via embolic dislodgment during transvenous lead removal (TLR).

Objective: The purpose of this study was to examine stroke and its associated factors in patients undergoing TLR for CIED infection. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15475271183079
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http://dx.doi.org/10.1016/j.hrthm.2018.08.008DOI Listing
November 2018
6 Reads

Cryptogenic Stroke and Significance of the Patent Foramen Ovale: A Case Series.

Cureus 2018 Oct 30;10(10):e3525. Epub 2018 Oct 30.

Internal Medicine, University of Tennessee Health Science Center, Memphis, USA.

Stroke is the second leading cause of death globally and can lead to significant adverse outcomes in patients following the acute illness. Due to this high morbidity and mortality, adequate interventions can play a significant role in health outcomes. Patent foramen ovale is one of the major proposed causes of cryptogenic strokes and can be present in up to 25% of general population. Read More

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http://dx.doi.org/10.7759/cureus.3525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318108PMC
October 2018
2 Reads

Anticoagulation in patients with Embolic Stroke of Unknown Source.

Authors:
J David Spence

Int J Stroke 2019 Jan 15:1747493019826363. Epub 2019 Jan 15.

Stroke Prevention & Atherosclerosis Research Centre, Robarts Research Institute, Western University, London, Canada.

When warfarin was the mainstay of anticoagulation for the prevention of cardioembolic stroke, the paradigm was essentially "we mustn't anticoagulate anyone unless we prove that the stroke was cardioembolic." Now that direct-acting oral anticoagulants are available, the paradigm should change. The risk of stroke is highest soon after the initial event, particularly in patients with more than one infarction. Read More

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http://dx.doi.org/10.1177/1747493019826363DOI Listing
January 2019
3 Reads

Stroke due to Paradoxical Embolization Related to Fibroid Uterus Enlargement Compressing the Right Common Iliac Vein.

Case Rep Neurol 2018 Sep-Dec;10(3):328-331. Epub 2018 Nov 23.

Department of Neurology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.

Stroke in young women is commonly cryptogenic or associated with an underlying hypercoagulable state (e.g., hormonal contraception). Read More

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http://dx.doi.org/10.1159/000494126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323390PMC
November 2018
3 Reads

Carcinoid heart disease involving the left heart: a case report and biomarker analysis.

ESC Heart Fail 2019 02 8;6(1):222-227. Epub 2019 Jan 8.

Department of Internal Medicine, Oberndorf Hospital, Salzburg, Austria.

Herein, we report the case of a 67-year-old woman who was admitted to our hospital because of dyspnoea and oedema of the lower extremities. Transthoracic echocardiography revealed severe tricuspid and mitral regurgitation, and the leaflets of the tricuspid valve were found to be rigid and almost immobile. The plasma concentrations of serotonin and chromogranin A were elevated, and hence, suspicion for carcinoid heart disease was raised. Read More

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http://doi.wiley.com/10.1002/ehf2.12396
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http://dx.doi.org/10.1002/ehf2.12396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352891PMC
February 2019
14 Reads

Interaction of cardiac implantable electronic device and patent foramen ovale in ischemic stroke: A case-only study.

Pacing Clin Electrophysiol 2019 Mar 31;42(3):341-348. Epub 2019 Jan 31.

Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri.

Background: Cardiovascular implantable electronic device (CIED) leads are a nidus for right atrial thrombi. Right-to-left thromboembolism across a patent foramen ovale (PFO) is a putative mechanism for ischemic stroke and PFO has been associated with stroke. We used a novel unbiased case-only study design to assess the effect modification of PFO-associated ischemic stroke risk by presence of CIED. Read More

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http://doi.wiley.com/10.1111/pace.13599
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http://dx.doi.org/10.1111/pace.13599DOI Listing
March 2019
8 Reads

Pediatric Acute Paradoxical Cerebral Embolism with Pulmonary Embolism Caused by Extremely Small Patent Foramen Ovale.

Open Med (Wars) 2019 24;14:10-13. Epub 2018 Dec 24.

Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, 30-1 Oyaguchi Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.

Herein, we report a pediatric case of acute paradoxical cerebral embolism complicated by serious acute pulmonary embolism that was caused by an extremely small patent foramen ovale (PFO). The patient had no medical history suggestive of any other reason. Paradoxical cerebral embolism may occur even with an extremely small PFO because of the increased right-side pressure of the heart and a resulting right-to-left shunt from the acute pulmonary embolism. Read More

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http://dx.doi.org/10.1515/med-2019-0002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310914PMC
December 2018
3 Reads

Mitral Valve Repair Versus Replacement in Elderly With Degenerative Disease: Analysis of the STS Adult Cardiac Surgery Database.

Ann Thorac Surg 2019 Mar 26;107(3):747-753. Epub 2018 Oct 26.

Division of Cardiac Surgery, Department of Surgery, University of Massachusetts Medical School, Worcester, Massachusetts; Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts. Electronic address:

Background: It has been postulated that mitral valve repair in the elderly does not confer short-term benefits over mitral valve replacement with complete preservation of the chordal apparatus. Our purpose was to test this hypothesis using data from The Society of Thoracic Surgeons Adult Cardiac Surgery Database (STS ACSD).

Methods: Patients aged 70 years or more undergoing primary isolated elective mitral valve repair or mitral valve replacement for degenerative disease were obtained from the STS ACSD versions 2. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2018.09.018DOI Listing
March 2019
3 Reads

Paradoxical embolism caused by ovarian vein thrombosis extending to inferior vena cava in a female with uterine myoma.

J Cardiol Cases 2018 Dec 5;18(6):207-209. Epub 2018 Sep 5.

Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan.

Deep vein thrombosis occasionally causes paradoxical embolism in patients with a patent foramen ovale (PFO). We report the case of a 42-year-old female who was hospitalized for stroke. Detailed investigations revealed the existence of a PFO, pulmonary embolism, and ovarian vein thrombosis extending to inferior vena cava. Read More

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http://dx.doi.org/10.1016/j.jccase.2018.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306514PMC
December 2018
2 Reads

Clinical Impact of Thrombophilia Screening in Young Adults with Ischemic Stroke.

J Stroke Cerebrovasc Dis 2018 Dec 27. Epub 2018 Dec 27.

Department of Neurology, Weill Cornell Medicine, New York, New York; Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York. Electronic address:

Objective: We evaluated the ability of genetic and serological testing to diagnose clinically relevant thrombophilias in young adults with ischemic stroke.

Methods: We performed a retrospective cohort study of patients aged 18-65 years diagnosed with acute ischemic stroke at a comprehensive stroke center between 2011 and 2015 with laboratory testing for thrombophilia. The primary outcome was any positive thrombophilia screening test. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10523057183070
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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.12.006DOI Listing
December 2018
6 Reads