2,995 results match your criteria Pasteurella Multocida Infection


Treatment of moderate grade dog bite wounds using amoxicillin-clavulanic acid with and without enrofloxacin: a randomised non-inferiority trial.

Aust Vet J 2021 Jun 20. Epub 2021 Jun 20.

School of Veterinary Science, University of Queensland, Gatton, Queensland, Australia.

Background: Dog-to-dog bite wounds are a common veterinary emergency presentation: despite this, there is insufficient information to guide veterinarians on appropriate empirical antimicrobial management.

Objectives: Investigate the effectiveness of amoxicillin-clavulanic acid with and without enrofloxacin in the treatment of moderate grade dog bite wounds (DBW). To describe common pathogens and their antimicrobial susceptibility patterns. Read More

View Article and Full-Text PDF

Wound infection caused by , a zoonotic pathogen: a case report.

Access Microbiol 2021 Mar 10;3(3):000196. Epub 2021 Feb 10.

Department of Microbiology and Infectious Diseases, Concord Hospital, NSW Health Pathology, Concord, NSW, Australia.

The isolation of from a 63-year-old female presenting to the emergency department following a cat bite injury to her right hand is described in this report. , also known as Centers for Disease Control (CDC) group EF-4b, is considered to be a zoonotic pathogen, and is usually associated with dog or cat bites. Despite the potential of this organism to cause serious soft tissue infections, it can be overlooked in routine clinical laboratories due to its slow growth characteristics and when the history of animal bite is not provided to the laboratory. Read More

View Article and Full-Text PDF

[Acute Hand Infections - Survey of the Pathogen Spectrum and appropriate Antibiotics].

Handchir Mikrochir Plast Chir 2021 Jun 16;53(3):219-223. Epub 2021 Jun 16.

Abteilung für Plastische, Ästhetische und Rekonstruktive Chirurgie, Universitätsklinik für Chirurgie, Medizinische Universität Graz.

Acute infections of the hand can be a pathology with severe consequences. Alongside the surgical therapy, it is necessary to establish a systemic antiinfective therapy as well. The most frequent bacteria in acute hand infections are Staphylococcus aureus and, less frequently, different Streptococci. Read More

View Article and Full-Text PDF

Detection of aerobic bacterial pathogens associated with early embryonic death in pregnant New Zealand female Rabbits in Egypt.

Vet World 2021 Apr 24;14(4):986-995. Epub 2021 Apr 24.

Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Agricultural Research Center, Nadi El-Seid Street, Dokki P.O. Box246, Giza 12618, Egypt.

Background And Aim: Rabbits are a highly sensitive species and susceptible to various bacterial pathogens that may be causative agents for early embryonic death. This study aimed to explore the administration of different bacterial agents in does suffering from early embryonic death. Furthermore, identification of genes associated with virulence was performed to identify the phenotypic and genotypic antimicrobial resistance patterns that may increase the virulence of pathogens and lead to early embryonic death. Read More

View Article and Full-Text PDF

The immune response and protective efficacy of a potential DNA vaccine against virulent Pasteurella multocida.

J Genet Eng Biotechnol 2021 May 31;19(1):81. Epub 2021 May 31.

Genetics Department, Faculty of Agriculture, Fayoum University, 63514, Fayoum, Egypt.

Background: Pasteurella multocida is the main cause of several infections of farm animals, and the immunity gained from commercial vaccines is for the short term only and needs to be routinely administered, so work on new vaccines against virulent P. multocida is crucial.

Results: In this study, the OmpH gene was amplified from ten P. Read More

View Article and Full-Text PDF

Biomarkers, immune responses and cellular changes in vaccinated and non-vaccinated goats during experimental infection of M. haemolytica A2 under tropical conditions.

Microb Pathog 2021 Aug 25;157:105001. Epub 2021 May 25.

Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.

Background: We investigated the biomarkers, immune responses and cellular changes in vaccinated and non-vaccinated goats experimentally challenged with M. haemolytica serotype A2 under rainy and hot tropical conditions. A total of twenty-four clinically healthy, non-pregnant, female goats randomly allocated to 2 groups of 12 goats each were used for the study. Read More

View Article and Full-Text PDF

The Profiles of Long Non-coding RNA and mRNA Transcriptome Reveals the Genes and Pathway Potentially Involved in Infection of New Zealand Rabbits.

Front Vet Sci 2021 5;8:591273. Epub 2021 May 5.

Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Taian, China.

Infection with () causes severe epidemic diseases in rabbits and is responsible for the pronounced economic losses in the livestock industry. Long non-coding RNAs (lncRNAs) have been proven to exert vital functions in regulating the host immune responses to bacterial attacks. However, little is known about how lncRNAs participate in the rabbit's immune response against infection in the lungs. Read More

View Article and Full-Text PDF

Case Report: CD8+ T-Lymphocyte Deficit: A Prerequisite for spp. Infection?

Front Med (Lausanne) 2021 27;8:668976. Epub 2021 Apr 27.

Bacteriology Laboratory, Limoges Teaching Hospital, Limoges, France.

Immunity against spp. is not well-known for humans. We've tested T CD8+ lymphocytes in a patient with a chronic prosthetic joint infection due to spp. Read More

View Article and Full-Text PDF

A Rare Case of Bacteremic Community-Acquired Pneumonia Due to Pasteurella Multocida Presenting With Hemoptysis.

Cureus 2021 Mar 31;13(3):e14232. Epub 2021 Mar 31.

Infectious Diseases, Ascension St. John Hospital, Detroit, USA.

(PM) is a gram-negative bacterium known to cause soft tissue infections, especially after animal bites, with some human infections occurring after animal exposure, usually via inhalation of contaminated secretions. PM pneumonia mainly affects those who are immunocompromised and in individuals with comorbidities. The spectrum of pulmonary disease due to PM is wide, ranging from pneumonia to empyema. Read More

View Article and Full-Text PDF

Pasteurella Multocida Bacteremia and Septic Arthritis in a Patient With Non-Bite Animal Exposure.

Cureus 2021 Mar 28;13(3):e14162. Epub 2021 Mar 28.

Internal Medicine Residency, Kettering Medical Center, Dayton, USA.

() is a gram-negative, facultative anaerobe, and it is most commonly found in the oropharynx of healthy domestic animals, especially cats and dogs.  is classified as an opportunistic pathogen, infecting individuals only through direct contact via local trauma caused by animal bites or scratches. More serious infections, while rare, are typically associated with immunocompromised states, known pre-existing cavitary lung pathology, or malignancy. Read More

View Article and Full-Text PDF

Virulence Determinants and Antimicrobial Profiles of Isolated from Cattle and Humans in Egypt.

Antibiotics (Basel) 2021 Apr 22;10(5). Epub 2021 Apr 22.

Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City, Minufiya 32897, Egypt.

is a Gram-negative bacterium that causes drastic infections in cattle and humans. In this study, 55 isolates were recovered from 115 nasal swabs from apparently healthy and diseased cattle and humans in Minufiya and Qalyubia, Egypt. These isolates were confirmed by existence, and molecular classification of the capsular types showed that types B, D, and E represented 23/55 (41. Read More

View Article and Full-Text PDF

Novel multi-strain probiotics reduces Pasteurella multocida induced fowl cholera mortality in broilers.

Sci Rep 2021 Apr 26;11(1):8885. Epub 2021 Apr 26.

Department of Microbiology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh.

Pasteurella multocida causes fowl cholera, a highly contagious poultry disease of global concern, causing significant ecological and economic challenges to the poultry industry each year. This study evaluated the effects of novel multi-strain probiotics consisting of Lactobacillus plantarum, L. fermentum, Pediococcus acidilactici, Enterococcus faecium and Saccharomyces cerevisiae on growth performance, intestinal microbiota, haemato-biochemical parameters and anti-inflammatory properties on broilers experimentally challenged with P. Read More

View Article and Full-Text PDF

Melting corneal ulcers (keratomalacia) in dogs: A 5-year clinical and microbiological study (2014-2018).

Vet Ophthalmol 2021 May 1;24(3):265-278. Epub 2021 Apr 1.

Davies Veterinary Specialists, Manor Farm Business Park, Hertfordshire, UK.

Objectives: To identify bacterial microorganisms associated with canine keratomalacia, review their antimicrobial sensitivity, and evaluate clinical outcomes compared to results of microbial culture.

Methods: Retrospective analysis of clinical records of dogs diagnosed with a melting corneal ulcer presented to a referral hospital in Hertfordshire, UK between 2014 and 2018.

Results: One hundred and ten melting corneal ulcers were sampled in 106 dogs. Read More

View Article and Full-Text PDF

Diversity and characterization of temperate bacteriophages induced in Pasteurella multocida from different host species.

BMC Microbiol 2021 Mar 30;21(1):97. Epub 2021 Mar 30.

Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, Sir Graeme Davies Building, University of Glasgow, 120 University Place, Glasgow, G12 8TA, UK.

Background: Bacteriophages play important roles in the evolution of bacteria and in the emergence of new pathogenic strains by mediating the horizontal transfer of virulence genes. Pasteurella multocida is responsible for different disease syndromes in a wide range of domesticated animal species. However, very little is known about the influence of bacteriophages on disease pathogenesis in this species. Read More

View Article and Full-Text PDF

Response of lymphatic tissues to natural feed additives, curcumin (Curcuma longa) and black cumin seeds (Nigella sativa), in broilers against Pasteurella multocida.

Poult Sci 2021 May 19;100(5):101005. Epub 2021 Jan 19.

Key Laboratory of Veterinary Pathobiology and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, Anhui, PR China. Electronic address:

The antibiotic residues and pathogenic resistance against the drug are very common in poultry because of antibiotics used in their feed. It is necessary to use natural feed additives as effective alternatives instead of a synthetic antibiotic. This study aimed to investigate the immune response of Nigella sativa and Curcuma longa in broilers under biological stress against Pasteurella multocida. Read More

View Article and Full-Text PDF

Influenza D virus in respiratory disease in Canadian, province of Québec, cattle: Relative importance and evidence of new reassortment between different clades.

Transbound Emerg Dis 2021 Mar 25. Epub 2021 Mar 25.

INRAE UMR 1225 IHAP-ENVT, Toulouse, France.

Background: Influenza D virus (IDV), a segmented single-stranded negative-sense ribonucleic acid (RNA) virus, belongs to the new Delta influenza virus genus of the Orthomyxoviridae family. Cattle were proposed as the natural reservoir of IDV in which infection was associated with mild-to-moderate respiratory clinical signs (i.e. Read More

View Article and Full-Text PDF

Pathogens associated with pleuritic pig lungs at an abattoir in Queensland Australia.

Aust Vet J 2021 May 9;99(5):163-171. Epub 2021 Mar 9.

Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, EcoSciences Precinct, Dutton Park, Queensland, 4102, Australia.

Objective: Pleurisy in pigs has economic impacts in the production stage and at slaughter. This study sought to establish if some micro-organisms can be found in high numbers in lungs with pleurisy by assessing batches of pigs at an abattoir in Queensland Australia.

Design: Samples of lung (including trachea/bronchus and lymph nodes) from a maximum of 5 pleurisy affected pigs were collected from 46 batches of pigs representing 46 Queensland farms. Read More

View Article and Full-Text PDF

Three novel immunogenic proteins determined through 2-Dimensional electrophoresis and mass spectrometry with immune serum confer protection against challenge with porcine Pasteurella multocida in mouse models.

Res Vet Sci 2021 May 13;136:303-309. Epub 2021 Mar 13.

State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China; The Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan, China. Electronic address:

Pasteurella multocida is an important zoonotic pathogen that causes multiple diseases in both animals and humans. Test of good immunogenic proteins is beneficial for vaccine development and disease control. In the present study, we determined four novel immunogenic proteins of P. Read More

View Article and Full-Text PDF

The lipopolysaccharide outer core transferase genes pcgD and hptE contribute differently to the virulence of Pasteurella multocida in ducks.

Vet Res 2021 Mar 4;52(1):37. Epub 2021 Mar 4.

Research Center of Avian Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, Sichuan, China.

Fowl cholera caused by Pasteurella multocida exerts a massive economic burden on the poultry industry. Lipopolysaccharide (LPS) is essential for the growth of P. multocida genotype L1 strains in chickens and specific truncations to the full length LPS structure can attenuate bacterial virulence. Read More

View Article and Full-Text PDF

Pasteurella multocida Bacteremia in an Immunocompromised Patient After Multiple Cat Scratches.

Cureus 2021 Jan 27;13(1):e12938. Epub 2021 Jan 27.

Internal Medicine, Medical Center of Trinity, Trinity, USA.

(P. multocida) is a zoonotic organism found in the normal flora of domestic and wild animals. In this case report, we present a 70-year-old Caucasian male who presented with fever, chills, and greenish sputum which began hours prior to presentation. Read More

View Article and Full-Text PDF
January 2021

Aldsulfin, a novel unusual anti-mannheimiosis epithiodiketopiperazine antibiotic produced by Lasiodiplodia pseudotheobromae FKI-4499.

J Antibiot (Tokyo) 2021 Jun 3;74(6):363-369. Epub 2021 Mar 3.

Ōmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.

An anti-mannheimiosis agent, aldsulfin, was isolated from a culture broth of the fungus Lasiodiplodia pseudotheobromae FKI-4499, together with a known compound, lasiodipline C, using bioassay-guided fractionation. Spectroscopic analysis of aldsulfin, using NMR, mass spectrometry, and CD analyses revealed it to be an epithiodiketopiperazine with an unstable and unusual hemithioaminal moiety. Aldsulfin showed antibacterial activity against Mannheimia haemolytica and Pasteurella multocida. Read More

View Article and Full-Text PDF

Transcriptomic Analysis of High- and Low-Virulence Bovine and .

Front Vet Sci 2021 10;8:616774. Epub 2021 Feb 10.

College of Veterinary Medicine, Southwest University, Chongqing, China.

is a gram-negative opportunistic pathogen that causes various diseases in poultry, livestock, and humans, resulting in huge economic losses. serotype A CQ6 (PmCQ6) is a naturally occurring attenuated strain, while serotype A strain CQ2 (PmCQ2) is a highly virulent strain isolated from calves. Compared with PmCQ2, it was found that bacterial loads and tissue lesions of lung tissue significantly decreased and survival rates significantly improved in mice infected with PmCQ6 by intranasal infection. Read More

View Article and Full-Text PDF
February 2021

Bovine respiratory coronavirus enhances bacterial adherence by upregulating expression of cellular receptors on bovine respiratory epithelial cells.

Vet Microbiol 2021 Apr 17;255:109017. Epub 2021 Feb 17.

Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, 889-2192, Japan; Graduate School of Medicine and Veterinary Medicine, University of Miyazaki, Miyazaki, 889-2192, Japan; Center for Animal Disease Control, University of Miyazaki, Miyazaki, 889-2192, Japan. Electronic address:

Bovine coronavirus (BCoV) is one of the agents causing bovine respiratory disease complex (BRDC), with single infection tending to be mild to moderate; the probability of developing pneumonia in BRDC may be affected by viral and bacterial combinations. Previously, we reported that bovine respiratory syncytial virus (BRSV) infection enhances adherence of Pasteurella multocida (PM) to cells derived from the bovine lower respiratory tract but that BRSV infection in cells derived from the upper respiratory tract reduces PM adherence. In this study, we sought to clarify whether the modulation of bacterial adherence to cells derived from the bovine upper and lower respiratory tract is shared by other BRDC-related viruses by infecting bovine epithelial cells from the trachea, bronchus and lung with BCoV and/or PM. Read More

View Article and Full-Text PDF

Particulate matter and airborne endotoxin concentration in calf barns and their association with lung consolidation, inflammation, and infection.

J Dairy Sci 2021 May 19;104(5):5932-5947. Epub 2021 Feb 19.

Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.

Agricultural operations are important sources of organic dust containing particulate matter (PM) and endotoxins, which have possible negative health consequences for both humans and animals. Dust concentrations and composition in calf barns, as well as the potential health effects for these animals, are scarcely documented. The objective of this study was to measure PM fractions and endotoxin concentrations in calf barns and study their associations with lung consolidation, respiratory tract inflammation, and infection in group-housed calves. Read More

View Article and Full-Text PDF

Efficacy of grape seed hydro-alcoholic extract in the treatment of experimentally Pasteurella multocida infected rabbits.

Vet Med Sci 2021 May 16;7(3):923-934. Epub 2021 Feb 16.

Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.

Pasteurellosis is one of the rabbit's most bacterial severe diseases and leads to considerable financial damages in large production systems worldwide. Antibiotic use in animals may lead to antibiotic residues in animal products, including meat. Therefore, this study was designed to evaluate the potential role of grape seed extract (GSE) in treating Pasteurella multocida infection in rabbits. Read More

View Article and Full-Text PDF

Antimicrobial Resistance in Bacteria Isolated From Cats and Dogs From the Iberian Peninsula.

Front Microbiol 2020 20;11:621597. Epub 2021 Jan 20.

Departament de Sanitat i Anatomia Animal, Universitat Autònoma de Barcelona, Barcelona, Spain.

Pet animals are assumed to be potential reservoirs in transferring antimicrobial resistance (AMR) to humans due to the extensively applied broad-spectrum antimicrobial agents and their close contact with humans. In this study, microbiological data and antimicrobial susceptibility results of dog ( = 5,086) and cat ( = 789) clinical samples from a private Laboratory of Diagnosis in Barcelona were analyzed. Samples came from different counties of the Iberian Peninsula during 2016-2018. Read More

View Article and Full-Text PDF
January 2021

Relationships among Fecal, Air, Oral, and Tracheal Microbial Communities in Pigs in a Respiratory Infection Disease Model.

Microorganisms 2021 Jan 27;9(2). Epub 2021 Jan 27.

Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA.

The association of the lower respiratory tract microbiome in pigs with that of other tissues and environment is still unclear. This study aimed to describe the microbiome of tracheal and oral fluids, air, and feces in the late stage of infection in pigs, and assess the association between the tracheal microbiome and those from air, feces, and oral fluids. Tracheal fluids (n = 73), feces (n = 71), oropharyngeal fluids (n = 8), and air (n = 12) were collected in seeder pigs (inoculated with ) and contact pigs (113 days post exposure to seeder pigs). Read More

View Article and Full-Text PDF
January 2021

Pharmacokinetic and Pharmacodynamic (PK/PD) Modeling and Establishment of the PK/PD Cutoff of Florfenicol Against in Ducks.

Front Microbiol 2020 11;11:616685. Epub 2021 Jan 11.

College of Veterinary Medicine, Yangzhou University, Yangzhou, China.

can invade and translocate through endothelial cells and result in vascular-system infection, which can cause severe economic losses in the poultry industry. Antibacterial therapy (especially florfenicol) plays an important part in controlling infection. To preserve the effect of florfenicol, pharmacokinetic/pharmacodynamic (PK/PD) modeling of florfenicol against three strains in duck was established. Read More

View Article and Full-Text PDF
January 2021

Oral flora of stray dogs and cats in Algeria: and other zoonotic bacteria.

Vet World 2020 Dec 30;13(12):2806-2814. Epub 2020 Dec 30.

Laboratory of Animal Reproduction Biotechnologies, Blida, Algeria.

Background And Aim: Knowledge of potentially pathogenic bacteria presents in the oral cavity of dogs and cats may be helpful in determining appropriate treatment for infected bite wounds. About 120.000 people are exposed to dog and cat bites every year in Algeria, but little is known about the dog and cat oral flora causing bite wound complications. Read More

View Article and Full-Text PDF
December 2020

Herd immunity drives the epidemic fadeout of avian cholera in Arctic-nesting seabirds.

Sci Rep 2021 Jan 13;11(1):1046. Epub 2021 Jan 13.

Department of Veterinary Pathology, University of Saskatchewan, Saskatoon, SK, S7N 5B4, Canada.

Avian cholera, caused by the bacterium Pasteurella multocida, is a common and important infectious disease of wild birds in North America. Between 2005 and 2012, avian cholera caused annual mortality of widely varying magnitudes in Northern common eiders (Somateria mollissima borealis) breeding at the largest colony in the Canadian Arctic, Mitivik Island, Nunavut. Although herd immunity, in which a large proportion of the population acquires immunity to the disease, has been suggested to play a role in epidemic fadeout, immunological studies exploring this hypothesis have been missing. Read More

View Article and Full-Text PDF
January 2021