Search Our Scientific Publications & Authors

Nat Commun 2019 Apr 17;10(1):1799. Epub 2019 Apr 17.

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA.

Chemoenzymatic modification of cell-surface glycan structures has emerged as a complementary approach to metabolic oligosaccharide engineering. Here, we identify Pasteurella multocida α2-3-sialyltransferase M144D mutant, Photobacterium damsela α2-6-sialyltransferase, and Helicobacter mustelae α1-2-fucosyltransferase, as efficient tools for live-cell glycan modification. Combining these enzymes with Helicobacter pylori α1-3-fucosyltransferase, we develop a host-cell-based assay to probe glycan-mediated influenza A virus (IAV) infection including wild-type and mutant strains of H1N1 and H3N2 subtypes. Read More

Microb Pathog 2019 Apr 10;131:170-174. Epub 2019 Apr 10.

Research Centre for Ruminant Diseases, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, Serdang, Malaysia.

Pasteurella multocida B:2 is a Gram-negative organism causing haemorrhagic septicaemia (HS) in buffaloes. It causes severe pulmonary infection, leading to infiltration of numerous macrophages and neutrophils. Despite the inflammatory response, buffaloes succumb to HS. Read More

Vet Microbiol 2019 Apr 18;231:207-213. Epub 2019 Mar 18.

College of Animal Science and Technology, Southwest University, Chongqing, 400715, China. Electronic address:

Pasteurella multocida is a Gram-negative bacterium that is responsible for a variety of diseases in birds and mammals, including humans. We have previously reported that the P. multocida serotype A strain PmCQ2 causes severe lung pneumonia in bovines. Read More

J Appl Microbiol 2019 Apr 7. Epub 2019 Apr 7.

IHMA Europe Sàrl, 1870, Monthey, Switzerland.

Aims: To present antimicrobial susceptibilities for bacteria from dogs and cats with respiratory tract infection (RTI) across Europe in 2013-2014 and compare with data from 2008-2010.

Methods And Results: MICs were determined for 464 isolates following CLSI standards using antibiotics approved for RTI treatment. Where possible, susceptibility was calculated using predominantly human-derived breakpoints whilst some antibiotics had no breakpoints. Read More

Trop Anim Health Prod 2019 Mar 27. Epub 2019 Mar 27.

Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.

Sudden death is usually the main finding in field animals during haemorrhagic septicaemia outbreaks caused by Pasteurella multocida type B:2 that causes acute, fatal and septicaemic disease in cattle and buffaloes. This situation may be due to failure in early detection of the disease where early treatment of antibiotics may improve the prognosis of the animal and other surviving animals. Thus, there is a grey area on the knowledge on the potential usage of pro-inflammatory cytokines and acute phase proteins as early biomarkers in the diagnosis of haemorrhagic septicaemia. Read More

J Vet Pharmacol Ther 2019 May 25;42(3):355-360. Epub 2019 Mar 25.

College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.

Pasteurella multocida is the causative agent of fowl cholera, and florfenicol (FF) has potent antibacterial activity against P. multocida and is widely used in the poultry industry. In this study, we established a P. Read More

J Immunoassay Immunochem 2019 Mar 21:1-14. Epub 2019 Mar 21.

d Pathobiology , Kwame Nkrumah University of Science and Technology , Kumasi , Ghana , USA.

There is a decline in sheep production and contribution to the economy. This study described the histological pattern, immunohistochemically demonstrate bacterial and viral agents of pneumonia in sheep slaughtered in metropolitan abattoirs in Nigeria and Ghana. A total of 805 (600 in Ghana and 205 in Nigeria) sheep lungs were examined for pneumonic lesions. Read More

Database (Oxford) 2019 01;2019

College of Animal Science and Technology, Southwest University, Chongqing, China.

Pasteurella multocida can infect a wide range of host, including humans and animals of economic importance. Genomics studies on the pathogen have produced a large amount of omics data, which are deposited in GenBank but lacks a dedicated and comprehensive resource for further analysis and integration so that need to be brought together centrally in a coherent and systematic manner. Here we have collected the genomic data for 176 P. Read More

Front Vet Sci 2019 4;6. Epub 2019 Feb 4.

College of Animal Science and Technology, Southwest University, Chongqing, China.

is a pathogenic microorganism that causes a variety of serious diseases in humans and animals worldwide. The global regulator gene, , plays an important role in pathogenesis and regulates the virulence of many bacteria. Here, we identified a gene in by complementing a Choleraesuis Δ mutant, and characterized a mutant strain of . Read More

Germs 2018 Dec 3;8(4):214-217. Epub 2018 Dec 3.

PhD, Laboratory of Clinical Microbiology and Molecular Microbiology, School of Medicine, University of Crete, 70013 Heraklion, Crete, Greece.

Introduction: Human pasteurellosis is a severe human infection that accounts for 20-30 human deaths annually worldwide. Mucous secretions derived from pets comprise the primary source of infection, which are transmitted through animal scratches or bites.

Case Report: We describe a case of wound infection in an immunocompetent adult with a decubitus ulcer of the lower extremity. Read More

BMC Microbiol 2019 Feb 11;19(1):37. Epub 2019 Feb 11.

Royal Veterinary College, Hawkshead Lane, Hatfield, Herts, AL9 7TA, UK.

Background: This study provides biochemical and molecular genetic characteristics of P. multocida isolated from dead saigas in 1988, 2010-2015 on the territory of the Republic of Kazakhstan.

Results: Bacteriological samples taken from carcasses of saiga antelope during mortality events recorded in West Kazakhstan in both 2010 and 2011 and in Kostanay in 2012 and 2015 confirmed the presence of P. Read More

J Vet Res 2018 Dec 31;62(4):439-445. Epub 2018 Dec 31.

Department of Pathology, Faculty of Veterinary Medicine, Van Yuzuncu Yil University, 65090, Van, Turkey.

Introduction: The aim of this study was to determine the predisposing effect of bovine respiratory syncytial virus (BRSV) on spp. infection in naturally-induced pneumonia in cattle by immunohistochemical labelling.

Material And Methods: Lungs of cattle slaughtered in the slaughterhouse were examined macroscopically, and 100 pneumonic samples were taken. Read More

J Vet Diagn Invest 2019 Jan 13:1040638718823850. Epub 2019 Jan 13.

California Animal Health & Food Safety Laboratory System, University of California-Davis, Turlock Branch, Turlock, CA.

Pasteurella multocida is the causative agent of fowl cholera, an economically important disease of commercial and backyard poultry. Turkeys are particularly susceptible to fowl cholera; both backyard and commercial turkeys can succumb to disease. On April 10, 2018, a dead 9-mo-old male Bronze turkey was submitted to the California Animal Health and Food Safety Laboratory System (CAHFS)-Turlock branch for postmortem examination. Read More

PLoS One 2019 10;14(1):e0210154. Epub 2019 Jan 10.

Department of Clinical Microbiology, Royal University Hospital and the Saskatchewan Health Authority, Saskatoon, Saskatchewan, Canada.

Actinobacillus pleuropneumoniae, Pasteurella multocida and Streptococcus suis are prevalent bacterial causes of swine infections. Morbidity, mortality and positively impacting the financial burden of infection occurs with appropriate antimicrobial therapy. Increasing antimicrobial resistance complicates drug therapy and resistance prevention is now a necessity to optimize therapy and prolong drug life. Read More

Microb Pathog 2019 Mar 4;128:206-214. Epub 2019 Jan 4.

Department of Immunology, Pathophysiology and Veterinary Preventive Medicine, Wroclaw University of Environmental and Life Sciences, C.K.Norwida 31 Str., 50-375, Wrocław, Poland.

Salmonella Enteritidis is one of the most common causes of food poisoning in humans. Many attempts have been made to develop an effective vaccine against S. Enteritidis for use in poultry, but experiments aimed at the complete elimination of this pathogen from poultry farms have not provided satisfactory results. Read More

Microb Pathog 2019 Mar 22;128:90-96. Epub 2018 Dec 22.

Institute of Science Biology, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address:

Haemorrhagic septicaemia (HS) is a well-known high fatality septicaemic disease happening among bovines. The disease is caused by the Pasteurella multocida serotype B:2 bacteria. P. Read More

BMJ Case Rep 2018 Dec 3;11(1). Epub 2018 Dec 3.

Internal Medicine, Spaarne Gasthuis Hoofddorp, Hoofddorp, The Netherlands.

is a known pathogen in humans, mostly reported after animal bite incidents. Atraumatic infections have been described, especially in immunocompromised patients. A 20-year-old patient with a history of stage IV Hodgkin's lymphoma with cavitating pulmonary lesions presented with a bilateral pneumonia. Read More

J Antimicrob Chemother 2019 Apr;74(4):851-853

Zoetis, Kalamazoo, MI, USA.

Objectives: To identify and analyse the first ESBL gene from Mannheimia haemolytica.

Methods: Susceptibility testing was performed according to CLSI. Plasmids were extracted via alkaline lysis and transferred by electrotransformation. Read More

J Community Hosp Intern Med Perspect 2018 11;8(6):370-372. Epub 2018 Dec 11.

Discovered by Louis Pasteur in 1880, Pasteurella multocida is the most common cause of zoonotic infection in humans which is transmitted via pet bites and/or scratches. However, animal contact may be absent or not identified in up to 40% of cases which usually occur in individuals with comorbidities. Despite having a low virulence, PM can cause serious and life threatening infections in rare instances. Read More

Microb Pathog 2019 Feb 7;127:202-207. Epub 2018 Dec 7.

Key Laboratory of New Animal Drug Project of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, PR China; Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou, 730050, China. Electronic address:

This study assessed the antimicrobial activity of 14-O-[(4,6-Diaminopyrimidine-2-yl) thioacetyl] mutilin (DPTM), a novel pleuromutilin candidate with a substituted pyrimidine moiety, against Pasteurella multocida. Minimum Inhibitory Concentration (MIC), Oxford Cup assay, and time-kill experiments were used to measure the activity of DPTM against P. multocida serotype A in vitro. Read More

Respir Med Case Rep 2019 9;26:31-34. Epub 2018 Nov 9.

Department of Pulmonary Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

, which colonizes upper respiratory and digestive tracts, is a leading cause of respiratory diseases in many host species. Here, we describe a case of pneumonia with hemoptysis. A 72-year-old female diagnosed with bronchiectasis with a 36-year history presented with a worsened infiltrative and granular shadow in the lower right lobe and lingular segment. Read More

J Vet Pharmacol Ther 2019 Jan 8;42(1):60-66. Epub 2018 Nov 8.

Guangdong Key Laboratory for Veterinary Drug Development and Safety Evaluation, South China Agricultural University, Guangzhou, China.

To explore the in vivo antimicrobial activity of cefquinome against Pasteurella multocida in piglets, a piglet tissue cage infection model was used in this study. After the population of P. multocida reached 10  CFU/mL in a tissue cage, piglets received an intramuscular administration of cefquinome at 0. Read More

J Vet Med Sci 2018 Dec 8;80(12):1861-1866. Epub 2018 Oct 8.

Fujian Provincial Key Laboratory for Avian Diseases Control and Prevention/Fujian Animal Diseases Control Technology Development Center, Institute of Animal Husbandry and Veterinary Medicine of Fujian Academy of Agricultural Sciences, Fuzhou 350013, People's Republic of China.

Muscovy duck parvovirus (MDPV) and goose parvovirus (GPV) have both been found to cause high mortality and morbidity in Muscovy ducklings. Specific detection is often rife with false positives due to high identity at the genomic nucleotide level and antigenic similarity between MDPVs and GPVs. In this study, significantly variable regions were found, via non-structural (NS) comparison, between MDPV and GPV NS genes; however, NS genes were conserved within the MDPV and GPV groups. Read More

J Infect Chemother 2019 Mar 5;25(3):197-199. Epub 2018 Sep 5.

Division of Infection Control and Prevention, Osaka University Hospital, Japan.

Pasteurella multocida, a zoonotic pathogen in humans, is known to be associated with skin and soft tissue infections following animal bites, but rarely causes visceral infections. We report a case of P. multocida-associated multiple intrapelvic abscesses in a young woman with uterine cervical cancer. Read More

J Vet Pharmacol Ther 2018 Dec 4;41(6):912-918. Epub 2018 Sep 4.

College of Veterinary Medicine, Yangzhou University, Yangzhou, China.

Pasteurella multocida (P. multocida) infection causes substantial economic loss in the duck industry. Danofloxacin, a fluoroquinolone solely used in animals, shows good antibacterial activity against P. Read More

BMC Infect Dis 2018 Aug 23;18(1):420. Epub 2018 Aug 23.

Division of infectious diseases and global public health, University of California San Diego, San Diego, USA.

Background: There are as many as 300,000 visits to the emergency department in the USA with animal bites every year. The most common infection after cat or dog bite is with Pasteurella Multocida. Many people infected will also have long-term central venous access for dialysis or for other reasons. Read More

Vet Rec Open 2018 31;5(1):e000293. Epub 2018 Jul 31.

Bacterial Disease Division, Animal and Plant Quarantine Agency, Gimcheon, Republic of Korea.

is one of the significant causes of respiratory infection outbreaks in the Korean pig industry. Although antimicrobial treatment is an effective strategy for controlling respiratory diseases, limited information is available regarding the antimicrobial susceptibility of the pathogens infecting Korean pigs. Therefore, in this study, we evaluated the antimicrobial resistance of against widely used antimicrobials in order to enable the selection of appropriate drugs and to evaluate any trends in resistance. Read More

IDCases 2018 24;13:e00429. Epub 2018 Jul 24.

University of Florida, Department of Medicine, Division of Infectious Diseases and Global Medicine, 1600 Southwest Archer Road, Gainesville, 32610 FL, United States.

J Virol Methods 2018 11 10;261:51-62. Epub 2018 Aug 10.

Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada; Canadian Food Inspection Agency, Lethbridge Laboratory, Lethbridge, AB, Canada. Electronic address:

Respiratory and enteric diseases continue to be two major causes of economic losses to the cattle industry worldwide. Despite their multifactorial etiology, the currently available diagnostic tests for bovine respiratory disease complex (BRDC) and bovine enteric disease (BED) are single-pathogen-tests. DNA microarray when combined with multiplex polymerase chain reaction (PCR) is a powerful tool in detection and differentiation of multiple pathogens in a single sample. Read More

Vet Microbiol 2018 Aug 17;222:114-123. Epub 2018 Jul 17.

Virginia-Maryland College of Veterinary Medicine, Department of Biomedical Sciences & Pathobiology, Virginia Tech, Blacksburg, VA, 24061, United States; Virginia Tech Carilion School of Medicine, Virginia Tech, Blacksburg, VA, 24061, United States. Electronic address:

Pasteurella multocida is the causative agent of avian cholera, an important economic and ecological disease that can present as a peracute, acute, chronic, or asymptomatic infection. Acute avian cholera is associated with encapsulated P. multocida, while chronic and asymptomatic cases of avian cholera may be associated with capsule-deficient P. Read More

Oxid Med Cell Longev 2018 27;2018:1780956. Epub 2018 Jun 27.

Department of Pharmacology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.

The present study investigated the efficacy of allicin as an antibacterial, anti-inflammatory, antioxidant, and immunostimulant agent in reducing the severity of () type B infection in rabbits. Fifty New Zealand rabbits, 5 weeks old, were divided equally into five groups. Except for group 1, all groups were intranasally infected with type B (2 × 10 colony forming units/ml/rabbit). Read More

J Med Microbiol 2018 Sep 17;67(9):1383-1390. Epub 2018 Jul 17.

4​Department of Microbiology, Tehran North Branch, Islamic Azad University, Tehran, Iran.

Purpose: Pasteurella multocida (P. multocida) is a principal pathogen of domestic animals and an opportunistic pathogen of humans. It is the causative agent of pneumonia and haemorrhagic septicaemia in cattle, sheep and goats, fowl cholera in chickens and progressive atrophic rhinitis in swine. Read More

Avian Dis 2018 Jun;62(2):184-188

A Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada, NIG 2W1.

Since being successfully reintroduced into Ontario, Canada, wild turkey ( Meleagris gallopavo) populations have undergone robust growth and range expansion. This, along with increases in land use changes from human population growth and subsequent developments in agriculture and livestock production, has heightened opportunities for interactions between wild turkeys, domestic poultry, and humans. As conspecifics, wild and domestic turkeys are susceptible to infection and disease from many of the same pathogens. Read More

IDCases 2018 19;12:136-139. Epub 2018 May 19.

Division of Infectious Diseases, Shizuoka Cancer Center Hospital, Sunto-gun, Shizuoka, Japan.

We report a case of pneumonia. A 71-year old Japanese woman with pulmonary infiltration of the lingual division of left lung 3 years before, which was thought to be caused by non-tuberculous mycobacteriosis (NTM) was referred to our clinic on account of chronic cough, sputum, dyspnea, and left pulmonary infiltration. Although she owned over 10 cats, no bites or scratches were mentioned. Read More

Vaccine 2018 07 13;36(30):4477-4484. Epub 2018 Jun 13.

Key Laboratory of Bacteriology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China. Electronic address:

The Gram-negative pathogen toxigenic P. multocida causes progressive atrophic rhinitis (PAR) in swine throughout the world. Although some vaccines are being developed against PAR, their efficacy has not been evaluated using carbopol. Read More

J Infect Public Health 2019 Jan - Feb;12(1):95-96. Epub 2018 Jun 13.

Department of Internal Medicine, General Hospital of Rethymno, 74100 Rethymno, Crete, Greece.

Pasteurella multocida is a rare cause of bacterial meningitis, more frequently affecting humans at the extremes of age. We report a case of meningitis and bacteremia caused by P. multocida in a 67-year-old diabetic woman who was living with 10 cats. Read More

Microb Pathog 2018 Sep 8;122:180-183. Epub 2018 Jun 8.

Avenida Fernando Corrêa da Costa, nº 2367 - Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.

Pasteurella multocida is one of the most important pathogen that causes pneumonia in swine. Although several virulence factors are known, the pathogenesis of this bacterium is not well-studied. Therefore, to study the pathogenesis of P. Read More

Vet Microbiol 2018 Jul 30;220:33-38. Epub 2018 Apr 30.

Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan; Center for Animal Disease Control, University of Miyazaki, Miyazaki, Japan. Electronic address:

Primary infection with bovine respiratory syncytial virus (BRSV) predisposes cattle to secondary infection with bacteria that cause bovine respiratory disease complex (BRDC). However, the interaction between BRSV and bacteria is unclear. This in vitro study examined the adherence of Pasteurella multocida (PM) to BRSV-infected cells was assessed in colony forming unit assays, by flow cytometry analysis, and by indirect immunofluorescence analysis (IFA) of epithelial cells (A549, HEp-2, and MDBK). Read More

Front Microbiol 2018 18;9:1038. Epub 2018 May 18.

National Reference Laboratory of Veterinary Drug Residues, Laboratory of Veterinary Pharmacology, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.

Tildipirosin, a 16-membered-ring macrolide antimicrobial, has recently been approved for the treatment of swine respiratory disease and bovine respiratory disease. This macrolide is extensively distributed to the site of respiratory infection followed by slow elimination. Clinical efficacy has been demonstrated in cattle and swine clinical field trials. Read More

Lett Appl Microbiol 2018 Sep 17;67(3):244-253. Epub 2018 Jul 17.

Division of Veterinary Microbiology & Immunology, FVSc & A.H., Shuhama (Aulesteng), SKUAST-K, Shalimar, India.

Currently used alum precipitated and oil adjuvant vaccines against HS caused by Pasteurella multocida B:2, have side effects and short-lived immunity, leading to regular catastrophic outbreaks in bovines in Asian subcontinent. The need for the development of an improved vaccine with longer immunity and the ability to differentiate between vaccinated and infected is essential. Pasteurella phage isolated in present study belongs to family Siphoviridae. Read More

Vet Microbiol 2018 Jun 4;219:165-170. Epub 2018 Apr 4.

Institute of Farm Animal Genetics, Friedrich-Loeffler-Institut (FLI), Neustadt-Mariensee, Germany.

The collaboration project VASIB aims at reducing the antibiotic consumption in pig production by integrating information from consulting expertise in clinical inspection, hygiene, epidemiology, microbiology and pharmacology. In this VASIB subproject, we investigated the antimicrobial susceptibility and relatedness of porcine respiratory tract pathogens. Bordetella bronchiseptica (n = 47), Pasteurella multocida (n = 18) and Streptococcus suis (n = 58) were obtained from weaner pigs at two farms. Read More

Emerg Infect Dis 2018 06;24(6):1145-1146

We report a case of urinary tract infection caused by an unusual genotype (sequence type 211) of Pasteurella multocida associated with human infection. Molecular genetic analysis of P. multocida isolates obtained from the human patient and his pet strongly suggests a zoonotic transmission of this bacterium. Read More

Case Rep Infect Dis 2018 22;2018:2574184. Epub 2018 Mar 22.

Division of Pulmonary and Critical Care Medicine, Bronx Lebanon Hospital Center Affiliated with Icahn School of Medicine at Mount Sinai, 1650 Grand Concourse, Bronx, NY 10457, USA.

Introduction: is a gram-negative coccobacillus pathogenic to animals. It can cause infection in humans by a bite, scratch, or lick from a cat or dog. can cause a variety of infections in humans, including cellulitis, osteomyelitis, endocarditis, peritonitis, and septic shock. Read More

Lung India 2018 May-Jun;35(3):237-240

Department of Medicine, Boonshoft School of Medicine, Dayton, Ohio, United States.

Pasteurella multocida infection is most commonly associated with the immunocompromised, mostly in the form of soft-tissue infection, although other sites of infection are still possible and have been reported in the immunocompetent. We report a case of an immunocompetent male with a history of exposure to carrier organisms without portal of entry who developed P. multocida pneumonia with bacteremia. Read More

J Vet Med Sci 2018 Jun 25;80(6):921-929. Epub 2018 Apr 25.

1) Department of Veterinary Medicine, Rongchang Campus of Southwest University, Chongqing 402460, China.

Fowl cholera caused by Pasteurella multocida has always been a disease of global importance for poultry production. The aim of this study was to obtain more information about the epidemiology of avian P. multocida infection in southwest China and the genetic characteristics of clinical isolates. Read More

J Feline Med Surg 2019 Feb 18;21(2):148-155. Epub 2018 Apr 18.

1 Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH, USA.

Objectives: The aim of this study was to compile an overview of the clinical features of intracranial complication of otitis media/interna (OMI) in cats managed across five veterinary referral hospitals. Of additional interest were culture results that could inform empirical antibiotic selection, as well as outcome with both medical and surgical management.

Methods: A retrospective medical record review was conducted at five veterinary referral practices to identify cats with a diagnosis of intracranial complication secondary to OMI between 2009 and 2017. Read More

Trauma Case Rep 2018 Feb 27;13:18-21. Epub 2017 Nov 27.

Department of Bacteriology, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy (University Mohammed V), Rabat, Morocco.

can cause serious infections after dog or cat bite. We report here a rare case of hand infection caused by consecutive to an injury by a thorn of the prickly pear. It caused an amputation of the distal phalanx of the thumb in a trisomic patient. Read More

J Feline Med Surg 2019 Feb 5;21(2):103-108. Epub 2018 Mar 5.

1 Laboratory of Veterinary Internal Medicine, Division of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan.

Objectives: Feline gingivostomatitis (FGS) is a painful chronic inflammatory disease of the oral cavity. The purpose of this study was to examine the frequency of detection of certain common feline bacteria and viruses to determine any potential associations with FGS.

Methods: A multicentre case-control study design was conducted. Read More

J Med Microbiol 2018 Feb 13. Epub 2018 Feb 13.

5​Service de Médecine Interne, Maladies Infectieuses et Immunologie Clinique, Hôpital Robert Debré, Avenue Général Koenig, 51100 Reims, France.

Pasteurella multocida is rarely observed in human chronic infections. A Pasteurella multocida strain was isolated from a skin biopsy of chronic dermohypodermitis in a 21-year-old woman without an immunocompromised state. As this strain was viable one month after a cat scratch despite treatment by amoxicillin-clavulanic acid, we compared this strain's growth rate, amoxicillin Minimal Inhibitory and Bactericidal Concentrations (MIC and MBC), resistance to serum and ability to activate neutrophil granulocytes with those of control strains isolated during acute infections in humans without previous antibiotics exposure. Read More

RNA 2018 05 12;24(5):704-720. Epub 2018 Feb 12.

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia.

is a Gram-negative bacterium responsible for many important animal diseases. While a number of virulence factors have been identified, very little is known about how gene expression and protein production is regulated in this organism. Small RNA (sRNA) molecules are critical regulators that act by binding to specific mRNA targets, often in association with the RNA chaperone protein Hfq. Read More