12,937 results match your criteria Parotid Malignant Tumors


Necrotizing sialometaplasia can hide the presence of salivary gland tumors. A case series.

Oral Dis 2019 Feb 18. Epub 2019 Feb 18.

Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

Objective: Necrotizing sialometaplasia (NS) is an uncommon benign process which affects minor and, more rarely, major salivary glands. While self-limiting, the condition might be clinically and histologically mistaken for malignancy. Furthermore, NS may accompany neoplasms. Read More

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http://doi.wiley.com/10.1111/odi.13066
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http://dx.doi.org/10.1111/odi.13066DOI Listing
February 2019
5 Reads

[Clinicopathological features and possible prognostic factors in parotid lymphomas].

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Feb;51(1):35-42

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

Objective: To investigate the clinicopathological features and prognostic factors in lymphoma of parotid origin.

Methods: Clinicopathological data of the patients with parotid lymphoma who were initially diagnosed in Peking University Hospital of Stomatology from 2006 to 2016 were collected and analyzed retrospectively. The patients were followed-up for 5 to 149 months with a median period of 45 months, and the factors influencing the prognosis were evaluated. Read More

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http://dx.doi.org/10.19723/j.issn.1671-167X.2019.01.007DOI Listing
February 2019

Mucoepidermoid carcinoma of the head and neck in children.

Int J Pediatr Otorhinolaryngol 2019 Feb 10;120:93-99. Epub 2019 Feb 10.

Department of Otolaryngology & Communication Enhancement, Boston Children's Hospital, Boston, MA, 02115, United States; Department of Otolaryngology, Harvard Medical School, Boston, MA, 02115, United States. Electronic address:

Introduction: Mucoepidermoid carcinoma is a rare malignant salivary gland neoplasm in the pediatric population. Few studies have discussed best practice with respect to diagnosis and treatment in children.

Objective: To present our institution's experience with the evaluation and management of pediatric mucoepidermoid carcinoma of the head and neck. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.02.020DOI Listing
February 2019

Two case reports of synchronous unilateral pleomorphic adenoma and cystadenolymphoma of the parotid gland with literature review.

J Ultrason 2018 ;18(75):369-373

Department of Otorhinolaryngology, Head and Neck Surgery , Klinikum Augsburg, Augsburg , Germany.

Synchronous unilateral tumors in the parotid glands account for less than 5-10% of all salivary gland neoplasms. Mostly these are cystadenolymphomas, but tumors of different histological types can be found as well. In these cases it is often pleomorphic adenoma in combination with cystadenolymphoma. Read More

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http://dx.doi.org/10.15557/JoU.2018.0055DOI Listing
January 2018
1 Read

Spontaneously infarcted parotid tumours: MRI findings.

Dentomaxillofac Radiol 2019 Feb 12:20180382. Epub 2019 Feb 12.

4 Department of Radiology, Osaka University Graduate School of Medicine , Osaka-sayama, Osaka , Japan.

Objectives:: To report MRI findings of spontaneous infarction in parotid tumours.

Methods:: 14 patients (13 male, 1 female; mean age 73 years) with spontaneously infarcted parotid tumours were reviewed retrospectively. MR images were assessed for the location, the presence of synchronous parotid masses, margin characteristics, signal intensity on T and T weighted images, and internal architecture according to the distribution of T signal hyperintensity. Read More

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http://dx.doi.org/10.1259/dmfr.20180382DOI Listing
February 2019

Ectopic pleomorphic adenoma on subcutaneous plane of the cheek.

Arch Craniofac Surg 2019 Feb 1. Epub 2019 Feb 1.

Department of Plastic and Reconstructive Surgery, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.

Pleomorphic adenoma is the most common benign tumor of the salivary gland. Pleomorphic adenoma occurs most commonly in the parotid gland but it may involve other salivary gland such as submandible or lingual. We report an ectopic pleomorphic adenoma in the subcutaneous layer of the face. Read More

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http://e-acfs.org/journal/view.php?doi=10.7181/acfs.2018.019
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http://dx.doi.org/10.7181/acfs.2018.01949DOI Listing
February 2019
6 Reads

Utility of metabolic heterogeneity factor in differentiating malignant versus benign parotid uptake on F FDG PET-CT.

Am J Nucl Med Mol Imaging 2018 20;8(6):415-420. Epub 2018 Dec 20.

Department of Nuclear Medicine and PET, John Hunter and Calvary Mater Hospitals Newcastle NSW, Australia.

Differentiation of benign and malignant parotid uptake on Fluorine 18 Fluro-Deoxy-Glucose Positron Emission Tomography-Computed Tomography (F FDG PET-CT) is of paramount importance due to the poor prognosis of the later but usual quantitative measures such as standardized uptake value (SUV) are not reliable for this purpose. Metabolic heterogeneity, being a characteristic of malignant tumors, would potentially be able to make this distinction. In this study, seventy-one FDG-avid parotid lesions were retrospectively separated histologically into benign and malignant groups. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334206PMC
December 2018

Retrograde parotidectomy under local anesthesia for benign, malignant, and inflammatory lesions.

Am J Otolaryngol 2019 Jan 14. Epub 2019 Jan 14.

Department of Otolaryngology-Head and Neck Surgery, Stanford University, 801 Welch Road, Stanford, CA, USA 94305. Electronic address:

Objective: To report the patient selection, surgical technique, and outcomes of parotidectomy using local anesthesia under monitored anesthesia care (MAC).

Methods: A retrospective chart review was performed for patients undergoing parotidectomy under local anesthesia at an academic head and neck surgery center.

Results: Six patients deemed high risk for general anesthesia (GA) due to medical comorbidities or with a strong preference to avoid GA underwent parotidectomy using local anesthesia and MAC. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.01.002DOI Listing
January 2019
1 Read

Results of cystadenolymphoma treatment of superficial parotid gland.

Otolaryngol Pol 2018 Sep;72(6):23-30

Collegium Medicum Uniwersytetu Mikołaja Kopernika w Toruniu Klinika Otolaryngologii i Laryngologii Onkologicznej z Pododdziałem Audiologii i Foniatrii.

Introduction Warthin's tumor is a non-malignant tumor that occurs in major salivary glands. Diagnostics include an interview and physical examination as well as additional tests - ultrasonography, magnetic resonance tomography, fine-needle aspiration biopsy. Surgical tumor resection remains the method of treatment, the scope of which includes techniques from extracapsular tumor resection to a full range of parotidectomy. Read More

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http://dx.doi.org/10.5604/01.3001.0012.4667DOI Listing
September 2018

[Terebrant basal cell carcinoma].

Pan Afr Med J 2018 30;30:300. Epub 2018 Aug 30.

Service de Dermatologie-Vénérologie, Hôpital d'Instruction Mohammed V, Rabat, Maroc.

Basal cell carcinoma (BCC) is the most frequent skin cancer. It never affects the mucosa. It is characterized by a local malignancy with an extremely rare risk of developing distant metastasis and the lowest mortality. Read More

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http://www.panafrican-med-journal.com/content/article/30/300
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http://dx.doi.org/10.11604/pamj.2018.30.300.16224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320449PMC
January 2019
3 Reads

The diagnostic performance of ultrasonography and computerized tomography in differentiating superficial from deep lobe parotid tumours.

Clin Otolaryngol 2019 Jan 12. Epub 2019 Jan 12.

Department of Otolaryngology Head and Neck Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan (R.O.C.).

Objectives: To validate and compare ultrasound (US) versus computerized tomography (CT) criteria in the localisation of superficial/deep lobe tumours of the parotid gland.

Design And Setting: This was a retrospective study of diagnostic tests performed from January 2008 to June 2017.

Participants: We included adult patients who were referred for a neck ultrasonography examination due to parotid tumours, and who subsequently underwent parotid surgery. Read More

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http://dx.doi.org/10.1111/coa.13289DOI Listing
January 2019
1 Read

[Clinical pathologic analysis on 3 724 cases of salivary gland tumors].

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Jan;54(1):10-16

Department of Pathology, Hospital of Stomatology, Jilin University, Changchun 130021, China.

To investigate the incidence and proportion of salivary gland tumors in order to provide new thinking for clinical diagnosis and treatment. Collected 3 724 cases salivary gland tumors diagnosed by Pathology Department of Hospital of Stomatology, Jilin University from January 1961 to December 2016. The pathological diagnosis referred to the fourth edition of head and neck-salivary gland tumor histopathological classification standard of WHO. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1002-0098.2019.01.003DOI Listing
January 2019
2 Reads

Contrast-enhanced Multi-detector CT Examination of Parotid Gland Tumors: Determination of the Most Helpful Scanning Delay for Predicting Histologic Subtypes.

J Belg Soc Radiol 2019 Jan 3;103(1). Epub 2019 Jan 3.

Department of Radiology, Ansan Hospital, Korea, University College of Medicine, Ansan, KR.

Purpose: Although contrast-enhanced CT (computed tomography) is regarded as the preoperative imaging modality of choice for parotid gland tumor, scanning methods are highly variable. We aimed at determining the most helpful scanning delay for predicting histologic subtypes of parotid gland tumors.

Material And Methods: Based on the medical record review, we identified 293 patients with 296 parotid gland tumors who underwent uni- or biphasic neck CT examination using a 64-row detector CT with the same acquisition parameters except the scan delays that were: (1) unenhanced, (2) 40 seconds, (3) 50 seconds, and (4) 70 seconds after the beginning of contrast-media injection. Read More

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http://dx.doi.org/10.5334/jbsr.1596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319312PMC
January 2019

Comparative Role of Matrixins in Diagnostics of Parotid Gland Tumors.

Authors:
E V Kochurova

Bull Exp Biol Med 2019 Jan 8;166(3):383-385. Epub 2019 Jan 8.

I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation, Moscow, Russia.

The benign and malignant neoplasms in parotid gland have similar clinical presentations despite different tumor growth rates. The study compared the clinical and morphological data as well as the results of ELISA for MMP-2, MMP-8, MMP-9, TIMP-1, and TIMP-2 in salivary fluid yielded during primary examination of the patients with pleomorphic adenoma and adenocarcinoma of parotid gland. The examined biomarkers detected in salivary fluid in patients with various cancer types differed significantly (p≤0. Read More

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http://dx.doi.org/10.1007/s10517-019-04355-wDOI Listing
January 2019
1 Read

Pediatric follicular lymphoma of the parotid gland.

Arch Craniofac Surg 2018 Dec 27;19(4):279-282. Epub 2018 Dec 27.

Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea.

Primary malignant lymphoma rarely presents as a mass in the salivary gland. It accounts for about 1% of salivary gland tumors. The lymphomas of the parotid gland are mainly non-Hodgkin's lymphoma of B-cell follicular type. Read More

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http://dx.doi.org/10.7181/acfs.2018.02075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325339PMC
December 2018
1 Read

Intraductal Carcinoma of Salivary Glands Harboring TRIM27-RET Fusion with Mixed Low Grade and Apocrine Types.

Head Neck Pathol 2019 Jan 4. Epub 2019 Jan 4.

Department of Pathology and Laboratory Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, L25, Cleveland, OH, 44195, USA.

Intraductal carcinomas (IDCs) of salivary gland are rare neoplasms. Here, we report a case of IDCs harboring TRIM27-RET fusion with mixed low grade and apocrine types. A 79-year-old male presented with slowly-growing left parotid mass for 2. Read More

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http://link.springer.com/10.1007/s12105-018-0996-1
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http://dx.doi.org/10.1007/s12105-018-0996-1DOI Listing
January 2019
1 Read

Role of fine-needle aspiration in post liver transplant patients: A clinical/cytological review.

Diagn Cytopathol 2018 Dec 28. Epub 2018 Dec 28.

Department of Pathology, Rush University Medical Center, Chicago, Illinois.

Background: Fine-needle aspiration (FNA) of superficial and deep-seated lesions has been used with high sensitivity and specificity in the diagnosis of neoplastic and nonneoplastic lesions. However, literature of FNA in posttransplant patients is sparse, especially in postliver transplant. We undertook a retrospective study to evaluate the utility of FNA in the clinical management of post liver transplant patients. Read More

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http://dx.doi.org/10.1002/dc.24133DOI Listing
December 2018

Risk of high-grade malignancy in parotid gland tumors as classified by the Milan System for Reporting Salivary Gland Cytopathology.

J Oral Pathol Med 2018 Dec 21. Epub 2018 Dec 21.

Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: The Milan System for Reporting Salivary Gland Cytopathology (Milan System) has previously shown its diagnostic utility by categorizing the seven cytology findings in salivary gland lesions. However, there has been lack of study about the risk of high-grade malignancy in the cytology diagnosis based on the Milan System. Thus, we tried to identify the diagnostic ability of the Milan System for high-grade malignancy and to suggest an improved diagnostic approach for preoperative estimation of high-grade malignancy using the Milan System. Read More

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http://dx.doi.org/10.1111/jop.12816DOI Listing
December 2018

Progression of immunoglobulin G4-related disease to systematic lupus erythematosus after gastric cancer surgery: A case report.

Medicine (Baltimore) 2018 Dec;97(51):e13545

Department of Nephrology, Fujita Health University School of Medicine.

Rationale: Immunoglobulin G4 related disease (IgG4-RD) rarely coexists with other autoimmune diseases, though we had a patient whose primary clinical problem was shifted from IgG4-RD to systemic lupus erythematosus (SLE) after gastrectomy. The present paper aimed to report pathological findings and clinical course of the patient.

Patient Concerns: The patient was a male aged 74 years old with gastric cancer characterized by the following symptoms: Raynaud phenomenon, polyarthralgia, and swollen parotid glands on both sides. Read More

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http://Insights.ovid.com/crossref?an=00005792-201812210-0003
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http://dx.doi.org/10.1097/MD.0000000000013545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320217PMC
December 2018
3 Reads

Metachronous bilateral multifocal nodular oncocytic hyperplasia of the parotid gland.

J Stomatol Oral Maxillofac Surg 2018 Dec 16. Epub 2018 Dec 16.

University of Health Sciences, Ankara Application and Research Hospital, Department of Nuclear Medicine, Ankara, Turkey.

Multifocal nodular oncocytic hyperplasia (MNOH) is a rare lesion of the parotid gland and bilateral cases are extremely rare. We report the case of a 69-year-old woman who was operated from MNOH 10 years ago and the bilateralism of the case appeared 10 years later making the case metachronous. Read More

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http://dx.doi.org/10.1016/j.jormas.2018.12.009DOI Listing
December 2018

[Functional parotid surgery for removal of benign parotid tumors].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1810-1812

Department of Stomatology, Tongji Hospital, Tongji University.

To evaluate the effect of the application of functional parotid surgery for removal of benign parotid tumors and the prevention of Frey syndrome. One hundred and fifty-six cases with benign tumor were underwent functional regional parotidectomy. All tumors were smaller than 4 cm in diameter. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.23.010DOI Listing
December 2018
5 Reads

AHNS series: Do you know your guidelines? Diagnosis and management of salivary gland tumors.

Head Neck 2019 Feb 13;41(2):269-280. Epub 2018 Dec 13.

Otolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania.

This article is the next installment of the series "Do you know your guidelines" presented by the Education Committee of the American Head and Neck Society. Guidelines for the workup and management of tumors of the major and minor salivary glands are reviewed. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/hed.25499
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http://dx.doi.org/10.1002/hed.25499DOI Listing
February 2019
8 Reads

Values of fine-needle aspiration cytology of parotid gland tumors: A review of 996 cases at a single institution.

Head Neck 2019 Feb 9;41(2):358-365. Epub 2018 Dec 9.

Department of Pathology, Osaka Medical College, Osaka, Japan.

Background: We evaluated the diagnostic accuracy of fine-needle aspiration cytology (FNAC) in a large series of benign and malignant parotid tumors.

Methods: The FNAC diagnosis of 821 benign and 175 malignant parotid tumors managed at our department between 1999 and 2017 was correlated with the final histology.

Results: FNAC made a correct histopathological diagnosis in 72% of the benign parotid tumors; however, FNAC provided a correct grade in only 34% of the malignant tumors. Read More

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http://dx.doi.org/10.1002/hed.25503DOI Listing
February 2019

[Clinicopathologic and molecular features of myoepithelial tumors of salivary glands].

Zhonghua Bing Li Xue Za Zhi 2018 Dec;47(12):936-940

Department of Pathology, General Hospital of Eastern Theater Command, Nanjing 210002, China.

To investigate the clinicopathological, and molecular characteristics of myoepithelial tumors (MTs) of salivary glands. A total of 37 MTs cases including 13 malignant epithelial tumors (MMTs) and 24 benign epithelial tumors (BMTs) of salivary glands were identified from the archives of the Department of Pathology, General Hospital of Eastern Theater Command, dating from 2006 to 2016. Clinical features, histological patterns, immunohistochemical characteristics and status of EWSR1 gene rearrangement by fluorescence in situ hybridization (FISH) analysis were reviewed in all cases. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2018.12.008DOI Listing
December 2018
2 Reads

Malignant Peripheral Nerve Sheath Tumor of the Parotid Gland.

Indian J Surg Oncol 2018 Dec 16;9(4):629-632. Epub 2018 May 16.

1Surgical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.

Malignant peripheral nerve sheath tumor (MPNST) refers to spindle cell sarcomas arising from or separating in the direction of cells of peripheral nerve sheath. The MPNST of the parotid gland is an extremely rare tumor, accounts for < 5% of all soft tissue sarcomas, and carries a poor prognosis. In this article, we report a case of MPNST of parotid gland in a 45-year-old male and review its diagnostic and therapeutic challenges. Read More

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http://dx.doi.org/10.1007/s13193-018-0779-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265183PMC
December 2018
2 Reads

A patient with pilomatricoma in the parotid region: case report and review of the literature.

Rom J Morphol Embryol 2018 ;59(3):917-926

Department of Histology, University of Medicine and Pharmacy of Craiova, Romania;

Pilomatricoma is a benign skin tumor originating from the matrix cells of the hair follicles. Sometimes, its diagnosis can be difficult, especially in the preauricular region, where in the differential diagnosis, in addition to other dermal and subcutaneous masses, primary and secondary parotid gland tumor lesions must be also considered. A 34-year-old female was referred to our Institution with a right preauricular swelling over 12 months, which enlarged in the last two months. Read More

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January 2019
7 Reads

Salivary gland tumors in a Brazilian population: A 20-year retrospective and multicentric study of 2292 cases.

J Craniomaxillofac Surg 2018 Dec 26;46(12):2227-2233. Epub 2018 Sep 26.

Postgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte-UFRN, Av. Senador Salgado Filho, 1787-Lagoa Nova, Natal, RN, 59056-000, Brazil. Electronic address:

Purpose: Neoplasms of the salivary glands comprise more than thirty subtypes of lesions with various clinical behaviors. The present study aimed to describe the incidence and main features of salivary gland tumors in Brazil.

Material And Methods: A retrospective descriptive cross-sectional study was performed (1997-2017). Read More

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http://dx.doi.org/10.1016/j.jcms.2018.09.028DOI Listing
December 2018
2 Reads

Excision of tumors in the parapharyngeal space using an endoscopically assisted transoral approach: a case series and literature review.

J Int Med Res 2018 Dec 11:300060518816190. Epub 2018 Dec 11.

2 Department of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Objective: Magnetic resonance imaging (MRI) provides important information regarding tumors in the parapharyngeal space (PPS), revealing their origin, whether they are benign or malignant, and their relationships with surrounding structures.

Methods: Twelve tumors in the PPS were completely excised using an endoscopically assisted transoral approach (EATA). The MRI features were analyzed. Read More

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http://dx.doi.org/10.1177/0300060518816190DOI Listing
December 2018
3 Reads

Histological Subtypes and Clinical Behavior Evaluation of Salivary Gland Tumors.

Acta Med Port 2018 Nov 30;31(11):641-647. Epub 2018 Nov 30.

Department of Pathology. Centro Hospitalar São João. Porto. Unit of Pathology and Oncology. Department of Pathology. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.

Introduction: Salivary gland tumors include a wide spectrum of histological subtypes and clinical behavior, which we aim to evaluate.

Material And Methods: We performed a retrospective study of all salivary gland tumors diagnosed and treated at the Centro Hospitalar São João, Porto, between 2005 and 2015. Histological re- evaluation was performed in all cases and patient files were reviewed and both clinical and follow-up data were collected. Read More

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http://dx.doi.org/10.20344/amp.9023DOI Listing
November 2018
17 Reads

Richter Syndrome Presenting With Colon Localization.

Clin Nucl Med 2019 Feb;44(2):e87-e89

Dipartimento di Scienze Radiologiche, Radioterapiche ed Ematologiche, Istituto di Medicina Nucleare, Fondazione Policlinico Universitario A. Gemelli IRCCS-Università Cattolica del Sacro Cuore, Rome, Italy.

A 75-year-old man, who had been diagnosed with small lymphocytic lymphoma with cervical localization, underwent F-FDG PET/CT with iodinated contrast medium due to the appearance of cervical swelling suspected of illness relapse. PET/CT revealed intense F-FDG uptake in multiple cervical and subdiaphragmatic lymph nodes and in the left parotid. Moreover, diffuse uptake and wall thickening of the colon were evident; endoscopy with biopsy revealed a diffuse large B-cell lymphoma. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002393DOI Listing
February 2019
7 Reads

The evaluation of a hybrid biomechanical deformable registration method on a multistage physical phantom with reproducible deformation.

Radiat Oncol 2018 Dec 4;13(1):240. Epub 2018 Dec 4.

Department of Radiation Oncology, Beaumont Health System, Royal Oak, MI, USA.

Background: Advanced clinical applications, such as dose accumulation and adaptive radiation therapy, require deformable image registration (DIR) algorithms capable of voxel-wise accurate mapping of treatment dose or functional imaging. By utilizing a multistage deformable phantom, the authors investigated scenarios where biomechanical refinement method (BM-DIR) may be better than the pure image intensity based deformable registration (IM-DIR).

Methods: The authors developed a biomechanical-model based DIR refinement method (BM-DIR) to refine the deformable vector field (DVF) from any initial intensity-based DIR (IM-DIR). Read More

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http://dx.doi.org/10.1186/s13014-018-1192-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280462PMC
December 2018
3 Reads

Acinic cell carcinoma of parotid gland with cavernous sinus metastasis: A case report.

J Cancer Res Ther 2018 Oct-Dec;14(6):1428-1430

Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India.

Acinic cell carcinoma (AciCC) is a low-grade malignancy which rarely metastasizes to bone or cavernous sinuses. A 62-year-old male patient, previously treated for AciCC of right parotid with surgery and local radiotherapy, presented 10 years later with progressive visual impairment and restriction of ocular movements. Magnetic resonance imaging of the head and orbit showed an expansile lobulated mass with heterogeneous signal intensity in bilateral cavernous sinus with encasement of the internal carotid artery on both sides. Read More

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http://dx.doi.org/10.4103/0973-1482.192850DOI Listing
February 2019
12 Reads

Epidemiology of salivary gland tumours in an Eastern Caribbean nation: A retrospective study.

Ann Med Surg (Lond) 2018 Dec 8;36:148-151. Epub 2018 Nov 8.

Department of Clinical Surgical Science, University of the West Indies, St. Augustine, Trinidad and Tobago.

Objective: The epidemiology of the salivary glands tumour is not well documented in the Caribbean countries. Therefore, the aim of this study is to determine the local trend of salivary gland tumours with a review of current diagnostic techniques.

Design & Methods: Retrospective data was collected from the electronic database at the Pathology department of the San Fernando Teaching Hospital between the periods January 2005 to June 2015. Read More

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http://dx.doi.org/10.1016/j.amsu.2018.10.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240702PMC
December 2018
3 Reads

Dosimetric impact of Acuros XB dose-to-water and dose-to-medium reporting modes on VMAT planning for head and neck cancer.

Phys Med 2018 Nov 15;55:107-115. Epub 2018 Nov 15.

Department of Medical Sciences, University of Girona, C/Emili Grahit 77, 17003 Girona, Spain; Department of Radiology, Clínica Girona, Institut de Diagnòstic per la Imatge, C/Lorenzana 36, 17002 Girona, Spain. Electronic address:

Purpose: To assess the dosimetric impact of switching from the Analytical Anisotropic Algorithm (AAA) to Acuros XB (AXB) for both dose-to-medium (Dm) and dose-to-water (Dw) in VMAT for H&N patients. To study whether it should be linked to a change in the dose prescriptions to the PTVs and in the constraints to the OARs.

Methods: 110H&N patients treated with VMAT were included. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S11201797183131
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http://dx.doi.org/10.1016/j.ejmp.2018.10.024DOI Listing
November 2018
11 Reads

Effectiveness of Multi-Criteria Optimization-based Trade-Off exploration in combination with RapidPlan for head & neck radiotherapy planning.

Radiat Oncol 2018 Nov 23;13(1):229. Epub 2018 Nov 23.

Beatson West of Scotland Cancer Centre, Radiotherapy Physics, NHS Greater Glasgow and Clyde, 1053 Great Western Road, Glasgow, G12 0YN, UK.

Background: A new strategy is introduced combining the use of Multi-Criteria Optimization-based Trade-Off Exploration (TO) and RapidPlan™ (RP) for the selection of optimisation parameters that improve the trade-off between sparing of organs at risk (OAR) and target coverage for head and neck radiotherapy planning. Using both approaches simultaneously; three different workflows were proposed for the optimisation process of volumetric-modulated arc therapy (VMAT) plans. The generated plans were compared to the clinical plans and the plans that resulted using RP and TO individually. Read More

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http://dx.doi.org/10.1186/s13014-018-1175-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251185PMC
November 2018
11 Reads

Salivary Gland Malignancies.

Oral Maxillofac Surg Clin North Am 2019 Feb;31(1):125-144

Division of Oral and Maxillofacial Surgery, University of Texas Southwestern Medical School, Parkland Memorial Hospital, 5323 Harry Hines Boulevard, Mail Code 9109, Dallas, TX 75390, USA.

Salivary gland tumors are rare pathologic entities that are derived from major and minor salivary gland tissue located throughout the head and neck region. These tumors are distinctly heterogenous, comprising numerous cell types, especially those deemed malignant. The incidence of malignant salivary gland tumors is widely distributed in both adult and pediatric patient populations. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10423699183007
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http://dx.doi.org/10.1016/j.coms.2018.08.007DOI Listing
February 2019
10 Reads

Body Mass Index and Parotidectomy Outcomes.

J Craniofac Surg 2019 Jan;30(1):e54-e58

Department of Otolaryngology, Loyola University Medical Center, Maywood, IL.

Multiple specialties have demonstrated increased risk of certain postoperative complications in patients with an increased body mass index (BMI). The goal of this study was to understand the outcomes of patients undergoing parotidectomy with an increased BMI and to identify any other patient risk factors for postoperative complications. This study was a retrospective chart review of 432 patients. Read More

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http://Insights.ovid.com/crossref?an=00001665-900000000-9521
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http://dx.doi.org/10.1097/SCS.0000000000004973DOI Listing
January 2019
5 Reads

The Role of Real-Time Elastography in the Differential Diagnosis of Salivary Gland Tumors.

J Ultrasound Med 2018 Nov 13. Epub 2018 Nov 13.

Department of Otorhinolaryngology, Adnan Menderes University Hospital, Aydın, Turkey.

Objectives: The aim of the study was to scrutinize the value of qualitative elastography in the diagnosis of salivary gland masses.

Methods: Sixty patients were enrolled in this prospective study. Patients aged between 1 and 91 years (mean age, 48. Read More

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http://dx.doi.org/10.1002/jum.14851DOI Listing
November 2018

PLAG1, SOX10, and Myb Expression in Benign and Malignant Salivary Gland Neoplasms.

J Pathol Transl Med 2019 Jan 14;53(1):23-30. Epub 2018 Nov 14.

Department of Pathology, National Cancer Center, Goyang, Korea.

Background: Recent findings in molecular pathology suggest that genetic translocation and/oroverexpression of oncoproteins is important in salivary gland tumorigenesis and diagnosis. Weinvestigated PLAG1, SOX10, and Myb protein expression in various salivary gland neoplasm tissues.

Methods: A total of 113 cases of surgically resected salivary gland neoplasms at the NationalCancer Center from January 2007 to March 2017 were identified. Read More

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http://www.jpatholtm.org/journal/view.php?doi=10.4132/jptm.2
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http://dx.doi.org/10.4132/jptm.2018.10.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344797PMC
January 2019
14 Reads

Acceptable Weight Ranges for Research Tissue Procurement and Biorepositories, 2015-2017.

Biopreserv Biobank 2018 Oct 31. Epub 2018 Oct 31.

1 Ohio Consortium , Cooperative Human Tissue Network (CHTN) Midwestern Division, Columbus, Ohio.

Background: The Cooperative Human Tissue Network, Midwestern Division, is a National Cancer Institute-funded program that provides quality research biospecimens to qualified investigators. Consented human tissues are procured according to researcher specifications for weight (size) and preservation type; weights of samples in significant demand and limited supply are negotiated. Weights of procured tissues are entered into a dedicated biospecimen database. Read More

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http://dx.doi.org/10.1089/bio.2018.0068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308276PMC
October 2018
3 Reads

Diagnostic Accuracy of Fine Needle Aspiration Cytology in Lesions of Oral Cavity and Salivary Glands: A Clinico-Pathological Study.

Open Dent J 2018 28;12:782-790. Epub 2018 Sep 28.

Department of Pathology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, India.

Objective: Fine Needle Aspiration Cytology (FNAC) is a rapid, reliable and safe diagnostic tool used for various lesions of the oral cavity and salivary glands. The present study was undertaken to categorize the cytomorphology of the oral cavity and salivary gland lesions on FNAC and to assess the accuracy of FNAC in arriving at a diagnosis.

Materials And Methods: A prospective study on oral cavity swellings and salivary gland aspirates was done during a 2 year period from August 2015 to July 2017 in which a total of 70 FNAC's were performed. Read More

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http://benthamopen.com/FULLTEXT/TODENTJ-12-782
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http://dx.doi.org/10.2174/1745017901814010782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182874PMC
September 2018
23 Reads

VTIQ and VTQ in combination with B-mode and color Doppler ultrasound improve classification of salivary gland tumors, especially for inexperienced physicians.

Clin Hemorheol Microcirc 2018 Oct 16. Epub 2018 Oct 16.

Department of Radiology, Ludwig-Maximilians-Universität München, Munich, Germany.

Background: Ultrasound is the method of choice for preoperative evaluation of masses of the parotid glands. However, existing methods do not allow for definite differentiation between the most common benign and malignant tumors.

Objective: Thus, we evaluated the benefits of Virtual Touch Quantification (VTQ) and Virtual Touch imaging quantification (VTIQ) for improving preoperative evaluation of parotid tumors. Read More

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http://www.medra.org/servlet/aliasResolver?alias=iospress&am
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http://dx.doi.org/10.3233/CH-189312DOI Listing
October 2018
9 Reads

Coincidence of Malignant Melanoma and an Incidently Discovered Parotid Mass Presenting a Diagnostic Challenge.

Plast Reconstr Surg Glob Open 2018 Aug 7;6(8):e1897. Epub 2018 Aug 7.

Plastic Reconstructive and Aesthetic Surgery Department, Cumhuriyet University Medical Faculty, Sivas, Turkey.

Parotid masses coincided with skin tumors in head and neck region may represent a serious diagnostic challenge. Conventional imaging modalities such as computed tomography, magnetic resonance imaging may help to determine nature of the masses. Positron emission tomography - computed tomography imaging is reported to be useful for the detection of malignancy in the parotid gland. Read More

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http://Insights.ovid.com/crossref?an=01720096-201808000-0003
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http://dx.doi.org/10.1097/GOX.0000000000001897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181513PMC
August 2018
1 Read

Indeterminate dendritic cell neoplasm accompanied by eosinophilic pneumonia successfully treated by systemic steroid therapy: Report of the first case with muscular and parotid involvement and review of published work.

J Dermatol 2018 Dec 15;45(12):1444-1447. Epub 2018 Oct 15.

Department of Dermatology, Kansai Medical University Medical Center, Osaka, Japan.

A 34-year-old Japanese man presented with an indolent nodule on the right flank. Computed tomography of the chest and abdomen demonstrated a large nodule measuring 55 mm × 50 mm in the abdominal oblique muscle layer of the right flank, and several small nodules were seen in the muscle layer throughout the body and subcutaneous tissue of the lower abdomen. F-fluorodeoxyglucose-positron emission tomography/computed tomography revealed nodular lesions in the bilateral parotid glands, bilateral cervical lymph nodes and lower lobe of the right lung. Read More

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http://dx.doi.org/10.1111/1346-8138.14673DOI Listing
December 2018
8 Reads

Nodular fasciitis of the parotid gland: A challenging diagnosis on FNA.

Cancer Cytopathol 2018 Oct 12;126(10):872-880. Epub 2018 Oct 12.

Department of Pathology, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, Maryland.

Background: Nodular fasciitis (NF) is a clonal, self-limited proliferation that has only rarely been described in the parotid gland. Because of its potential to mimic benign and malignant parotid neoplasms clinically, radiographically, and cytomorphologically, NF is often managed with unnecessary surgery, which is associated with a risk for significant surgical complications. The purpose of this study is to present the clinical and cytomorphologic findings for NF of the parotid gland by fine-needle aspiration (FNA). Read More

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http://doi.wiley.com/10.1002/cncy.22049
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http://dx.doi.org/10.1002/cncy.22049DOI Listing
October 2018
3 Reads

Principal component analysis modeling of Head-and-Neck anatomy using daily Cone Beam-CT images.

Med Phys 2018 Dec 2;45(12):5366-5375. Epub 2018 Nov 2.

Department of Radiation Oncology, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI, 48202, USA.

Purpose: To model Head-and-Neck anatomy from daily Cone Beam-CT (CBCT) images over the course of fractionated radiotherapy using principal component analysis (PCA).

Methods And Materials: Eighteen oropharyngeal Head-and-Neck cancer patients, treated with volumetric modulated arc therapy (VMAT), were included in this retrospective study. Normal organs, including the parotid and submandibular glands, mandible, pharyngeal constrictor muscles (PCMs), and spinal cord were contoured using daily CBCT image datasets. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/mp.13233
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http://dx.doi.org/10.1002/mp.13233DOI Listing
December 2018
1 Read

Cutaneous melanoma in childhood presenting as intraparotid lymph node metastasis.

Indian J Pathol Microbiol 2018 Oct-Dec;61(4):567-569

Department of Pathology, National Reference Laboratory, Dr. Lal PathLabs, Rohini, New Delhi, India.

Cutaneous melanoma in childhood is a rare disease. Rendering a clinical diagnosis of melanoma in pediatric patients is confounded by the fact that pigmented lesions in pediatric patients do not conform to the ABCDE rules applicable to adult patients. Furthermore, making a histologic diagnosis of cutaneous melanoma in childhood is also difficult with no universally accepted criteria applicable to pediatric melanomas. Read More

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http://www.ijpmonline.org/text.asp?2018/61/4/567/242976
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http://dx.doi.org/10.4103/IJPM.IJPM_43_17DOI Listing
February 2019
8 Reads
0.642 Impact Factor

Dedifferentiation of oncocytic epithelial-myoepithelial carcinoma to mucoepidermoid carcinoma in parotid gland: A rare case report.

Indian J Pathol Microbiol 2018 Oct-Dec;61(4):564-566

Department of ENT, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India.

Epithelial-myoepithelial carcinomas (EMCs) account for <1% of all salivary gland malignancies. Till now, 23 cases of dedifferentiated EMC have been reported to the best of our knowledge. However, dedifferentiation of oncocytic EMC to mucoepidermoid carcinoma is extremely rare. Read More

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http://www.ijpmonline.org/text.asp?2018/61/4/564/242999
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http://dx.doi.org/10.4103/IJPM.IJPM_64_17DOI Listing
February 2019
4 Reads

Adaptive radiotherapy for head and neck cancer.

Acta Oncol 2018 Oct 5;57(10):1284-1292. Epub 2018 Oct 5.

a Radiotherapy Department , Centre Eugene Marquis , Rennes , France.

Introduction: Large anatomical variations can be observed during the treatment course intensity-modulated radiotherapy (IMRT) for head and neck cancer (HNC), leading to potential dose variations. Adaptive radiotherapy (ART) uses one or several replanning sessions to correct these variations and thus optimize the delivered dose distribution to the daily anatomy of the patient. This review, which is focused on ART in the HNC, aims to identify the various strategies of ART and to estimate the dosimetric and clinical benefits of these strategies. Read More

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https://www.tandfonline.com/doi/full/10.1080/0284186X.2018.1
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http://dx.doi.org/10.1080/0284186X.2018.1505053DOI Listing
October 2018
12 Reads

Adamantinoma-like Ewing Sarcoma of the Salivary Glands: A Newly Recognized Mimicker of Basaloid Salivary Carcinomas.

Am J Surg Pathol 2019 Feb;43(2):187-194

Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD.

Adamantinoma-like Ewing sarcoma (ALES) is a rare tumor that demonstrates the EWSR1-FLI1 translocation characteristic of Ewing sarcoma despite overt epithelial differentiation including diffuse expression of cytokeratins and p40. Most cases of ALES described to date have occurred in the head and neck where they can mimic a wide range of small round blue cell tumors. Because distinguishing ALES from basaloid salivary gland carcinomas can be particularly difficult, we analyzed a series of 10 ALESs that occurred in the salivary glands with the aim of identifying features that allow for better recognition of this entity. Read More

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http://Insights.ovid.com/crossref?an=00000478-900000000-9776
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http://dx.doi.org/10.1097/PAS.0000000000001171DOI Listing
February 2019
3 Reads