13,002 results match your criteria Parotid Malignant Tumors


Secretory Carcinoma of the Parotid: Making the Correct Diagnosis of a Rare Salivary Gland Carcinoma When Molecular Biology Testing Is Not Available.

Case Rep Pathol 2019 17;2019:5103496. Epub 2019 Mar 17.

Servicio de Patología, Hospital Metropolitano, Ecuador.

Secretory carcinoma (SC) is a recently described entity occurring in the salivary glands. Before its description, SC was frequently classified as acinic cell carcinoma (ACC) or adenocarcinoma, not otherwise specified. Its particular histopathological and immunohistochemical characteristics are reminiscent of breast secretory carcinoma. Read More

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http://dx.doi.org/10.1155/2019/5103496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441535PMC

Sensitivity of Fine-Needle Aspiration and Imaging Modalities in the Diagnosis of Low-Grade Mucoepidermoid Carcinoma of the Parotid Gland.

Ann Otol Rhinol Laryngol 2019 Apr 16:3489419842582. Epub 2019 Apr 16.

1 Department of Otolaryngology-Head and Neck Surgery, BS, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Objective: To determine the diagnostic accuracy of fine-needle aspiration (FNA) and imaging modalities for low-grade mucoepidermoid carcinoma (MEC) of the parotid gland.

Methods: Retrospective chart review of patients diagnosed with low-grade MEC of the parotid gland following surgical excision between January 2010 and June 2018. Imaging from patients with MEC were randomly mixed with imaging from patients with benign pathology and reviewed in a blinded fashion. Read More

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http://dx.doi.org/10.1177/0003489419842582DOI Listing

Myoepithelial Cell Carcinoma of the Oral Tongue: Case Report and Review of the Literature.

Clin Med Insights Oncol 2019 2;13:1179554919838254. Epub 2019 Apr 2.

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of New Mexico Hospital, UNM School of Medicine, Albuquerque, NM, USA.

Background: Myoepithelial cell carcinoma is a rare malignant neoplasm of salivary gland origin that typically presents in the parotid gland and minor salivary glands. It has been described previously in head and neck sites such as buccal mucosa, alveolar ridge, and base of tongue.

Methods: A 55-year-old man presented with 30 years of right-sided tongue pain and 10 years of gradually worsening ulceration. Read More

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http://dx.doi.org/10.1177/1179554919838254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448097PMC
April 2019
2 Reads

Metastatic lung cancer associated with Warthin's tumour.

Niger J Clin Pract 2019 Apr;22(4):585-587

Department of Pulmonary Diseases, Health Sciences University Bursa Yuksek Ihtisas Education and Research Hospital, Bursa, Turkey.

Warthin's tumors which can easily be subjected to misinterpretation are encountered commonly in clinical practice. Warthin's tumors which generally have the localization of parotid gland cauda and have a slow growing characteristic can rarely be seen aside from parotid gland; such as cervical lymph nodes and minor salivary glands. A 56-year-old patient's case that comprised atypical coexistence of Warthin tumor with PET/CT scan positive cervical lymph nodes during the diagnostic examination carried out for a pulmonary mass lesion is presented. Read More

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http://dx.doi.org/10.4103/njcp.njcp_424_18DOI Listing
April 2019
1 Read

Salivary gland carcinoma in Shanghai (2003-2012): an epidemiological study of incidence, site and pathology.

BMC Cancer 2019 Apr 11;19(1):350. Epub 2019 Apr 11.

Department of Oral & Maxillofacial - Head & Neck Oncology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Key Laboratory of Stomatology, Shanghai, 200011, China.

Background: Salivary gland carcinoma ranks the sixth in head and neck cancers while it is relatively rare in its incidence. Epidemiological studies have been based mostly on institutional data, leading to selection bias in incidence evaluation. Most population-based cancer registries have grouped cancers of the minor salivary glands with oral cancer instead of with salivary gland carcinoma as a whole, because of the international disease coding. Read More

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http://dx.doi.org/10.1186/s12885-019-5564-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458649PMC
April 2019
1 Read

High-Resolution MRI Microscopy Coil Assessment of Parotid Masses.

Ear Nose Throat J 2019 Apr 8:145561319839898. Epub 2019 Apr 8.

1 Department of Radiology, University of Chicago, Pritzker School of Medicine, Chicago, IL, USA.

The goal of this study was to determine whether high-resolution magnetic resonance imaging (MRI) microscopy coil imaging can improve the depiction parotid masses. A total of 14 parotid masses, including 7 salivary neoplasms, 2 abnormal lymph nodes, and 5 benign cystic lesions were imaged with T2-weighted and fat-suppressed postcontrast T1-weighted sequences using a 47-mm diameter microscopy coil in addition to conventional MRI sequences acquired with a conventional head and neck neurovascular coil. Compared to conventional parotid MRI sequences, microscopy coil images provided better definition of the margins of neoplasms, provide more detailed definition of lymph node morphology, and better depict certain cyst contents in the superficial portions of the parotid gland. Read More

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http://dx.doi.org/10.1177/0145561319839898DOI Listing
April 2019
4 Reads

Salivary gland neoplasms in non-human primates: A case series and brief literature review.

J Med Primatol 2019 Apr 2. Epub 2019 Apr 2.

Southwest National Primate Research Center at the Texas Biomedical Research Institute, San Antonio, Texas.

Background: Salivary gland neoplasms are rare in non-human primates.

Methods: Thirty-five years of pathology records were reviewed at the Southwest (SNPRC) and Yerkes (YNPRC) National Primate Research Centers. An in-depth literature search for salivary gland neoplasms in non-human primates was performed. Read More

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http://dx.doi.org/10.1111/jmp.12412DOI Listing
April 2019
2 Reads

Diagnostic Accuracy of Multiparametric Magnetic Resonance Imaging for Differentiation Between Parotid Neoplasms.

Can Assoc Radiol J 2019 Mar 25. Epub 2019 Mar 25.

Departments of Diagnostic and Interventional Radiology, Mansoura University, Dakahlia, Egypt.

Purpose: This study was designed to evaluate the role of multiparametric magnetic resonance imaging (MRI) for differentiation of parotid gland neoplasms.

Methods: Prospective study was conducted upon 52 consecutive patients (30 men, 22 women; aged 24-78 years; mean, 51 years) with parotid tumours that underwent multiparametric MRI using combined static MRI, dynamic contrast enhanced (DCE) MRI, and diffusion-weighted imaging (DWI). The static MRI parameter, time signal intensity curves (TIC) derived from DCE-MRI, and apparent diffusion coefficient (ADC) values of parotid tumours were correlated with histopathological findings. Read More

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http://dx.doi.org/10.1016/j.carj.2018.10.010DOI Listing
March 2019
2 Reads

Oncological outcomes of parotid gland malignancies: a retrospective analysis of 74 patients.

J Stomatol Oral Maxillofac Surg 2019 Mar 22. Epub 2019 Mar 22.

Department of Otolaryngology-Head and Neck Surgery, University Hospital of Modena, University of Modena and Reggio Emilia, Modena, Italy.

Introduction: Salivary gland malignancies are rare neoplasms whose management has been evolving over the last two decades. Nevertheless, patient outcomes have not improved accordingly.

Objective: In the present paper, factors and variables that could influence Overall, Disease-Specific and Disease-Free Survival, and Loco-Regional Control were analyzed. Read More

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http://dx.doi.org/10.1016/j.jormas.2019.03.006DOI Listing

Immunohistochemical Assessment of BAP1 Protein in Mucoepidermoid Carcinomas.

Indian J Otolaryngol Head Neck Surg 2019 Mar 19;71(1):33-37. Epub 2018 Dec 19.

1Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029 India.

Mucoepidermoid carcinomas are common malignant salivary gland tumors. Despite recent advances in diagnosis and treatment, there has not been much improvement in outcome of these patients, necessitating identification of novel targeted therapeutic agents. Genomic profiling of mucoepidermoid carcinomas has recently revealed aberrations in gene. Read More

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http://dx.doi.org/10.1007/s12070-018-1549-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401040PMC
March 2019
1 Read

Lipoma of the Parotid Gland.

Head Neck Pathol 2019 Mar 19. Epub 2019 Mar 19.

Department of Oral & Maxillofacial Pathology, Naval Postgraduate Dental School, Naval Medical Professional Development Center, 8955 Wood Road, Bethesda, MD, 20889-5638, USA.

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http://dx.doi.org/10.1007/s12105-019-01023-3DOI Listing
March 2019
1 Read

Primary parotid liposarcoma.

Eur Ann Otorhinolaryngol Head Neck Dis 2019 Mar 12. Epub 2019 Mar 12.

School of Medicine, University of Zagreb, Šalata 3b, Zagreb, Croatia.

Introduction: Primary liposarcoma is very rare in the parotid gland. To date, only 8 cases of primary parotid liposarcoma have been reported. The aim of this study is to report on a case of primary parotid liposarcoma highlighting the complexity of its treatment and analyze treatment outcomes of other reported cases. Read More

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http://dx.doi.org/10.1016/j.anorl.2018.01.013DOI Listing
March 2019
1 Read

Management of accessory parotid gland tumours: 32-year experience from a single institution and review of the literature.

Int J Oral Maxillofac Surg 2019 Mar 9. Epub 2019 Mar 9.

University Hospital Centre 'Sisters of Mercy', University Hospital for Tumors, Department of Radiotherapy and Medical Oncology, Ilica, Zagreb, Croatia.

Accessory parotid gland tumours (APGTs) are very rare. Regarding their anatomical location, an adequate surgical approach is necessary to provide safe resection and satisfactory postoperative results. The aims of this study were to present our tertiary centre experience in surgical treatment and management of APGTs and to review the literature regarding their treatment, particularly in terms of surgical modalities. Read More

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http://dx.doi.org/10.1016/j.ijom.2019.02.014DOI Listing
March 2019
1 Read

Ossified Carcinoma Ex Pleomorphic Adenoma in accessory lobe of parotid gland: Complexity in clinical, imaging and histologic diagnosis and minimally invasive surgery.

Oral Oncol 2019 May 7;92:95-98. Epub 2019 Mar 7.

Maxillofacial Surgery Unit, Department of Maxillo-Facial Surgery, University of Naples "Federico II", Naples, Italy. Electronic address:

Carcinoma ex pleomorphic adenoma is not common among malignant salivary tumors and an accessory lobe of parotid gland tumor with a carcinoma ex pleomorphic adenoma histology is even rarer. Management of these tumors include a high index of suspicion, good understanding of the anatomy and a meticulous surgical access. The exceptional localization of an ossified Carcinoma ex Pleomorphic Adenoma in the accessory lobe of the parotid gland, never reported to date in the literature, has prompted us to report this case to stress the challenging difficulties related to clinical and histologic diagnosis and to analyze a minimally invasive intraoral approach. Read More

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http://dx.doi.org/10.1016/j.oraloncology.2019.03.003DOI Listing
May 2019
1 Read

More advantages in detecting bone and soft tissue metastases from prostate cancer using F-PSMA PET/CT.

Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7.

Department of Nuclear Medicine and PET/CT, Evangelismos General Hospital, Ypsilantou 45-47, PC 106 76, Athens, Greece.

Prostate cancer (PCa) is the most common solid cancer affecting men worldwide. Serum prostate-specific antigen (PSA) is at present the most commonly used biomarker for PCa screening, as well as a reliable marker of disease recurrence after initial treatment. Bone metastases (BM) are present in advanced stages of the disease. Read More

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http://dx.doi.org/10.1967/s002449910952DOI Listing
March 2019
9 Reads

[Relationship between morphological characteristics and prognosis of non-nasopharyneal EBV-associated carcinoma].

Zhonghua Bing Li Xue Za Zhi 2019 Mar;48(3):209-214

Department of Pathology, Zhejiang Chinese Medical University Affiliated Zhejiang Cancer Hospital, Hangzhou 310022, China.

To analyze the pathological features and their influence on the clinical outcome of non-nasopharyngeal EBV-associated carcinomas. One hundred and twenty cases of non-nasopharyngeal EBV-associated carcinoma confirmed by in situ hybridization were identified at Zhejiang Cancer Hospital from January 1, 2006 to May 1, 2018, and the clinicopathological data were collected and analyzed using Kaplan-Meier survival analysis, Cox univariate and multivariate analysis. One hundred and twenty cases were involved in the study; the male to female ratio was 1∶1; patients' age range was 24 to 89 years (median 50 years). Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2019.03.008DOI Listing
March 2019
4 Reads

Immunohistochemistry Using a Pan-TRK Antibody Distinguishes Secretory Carcinoma of Salivary Gland from Acinic Cell Carcinoma.

Histopathology 2019 Feb 23. Epub 2019 Feb 23.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

Aims: Secretory carcinoma (previously known as mammary analog secretory carcinoma) is characterized by ETV6 rearrangements, most often ETV6-NTRK3 fusion. Given its histologic overlap with other salivary gland tumors, secretory carcinoma can be difficult to diagnose without genetic confirmation. A recently developed pan-TRK antibody shows promise for identifying tumors with NTRK fusions. Read More

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http://dx.doi.org/10.1111/his.13845DOI Listing
February 2019
1 Read

Simultaneous occurrence of benign and malignant tumours in the ipsilateral parotid gland-retrospective study.

Int J Oral Maxillofac Surg 2019 Feb 21. Epub 2019 Feb 21.

Department of Oral Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Research Institute of Stomatology and Shanghai Key Laboratory of Stomatology, Shanghai, China. Electronic address:

The simultaneous occurrence of benign and malignant tumours in the ipsilateral parotid gland is extremely rare. The cases of five patients with synchronous multiple parotid gland tumours consisting of diverse combinations of benign and malignant histological types are presented here. In addition, all published cases of this entity identified in the PubMed, Embase, and Web of Science databases up to January 2018 were reviewed. Read More

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http://dx.doi.org/10.1016/j.ijom.2019.01.017DOI Listing
February 2019
3 Reads

The role of frozen section biopsy for parotid gland tumour with benign fine-needle aspiration cytology.

J Laryngol Otol 2019 Mar 21;133(3):227-229. Epub 2019 Feb 21.

Department of Otolaryngology,School of Medicine,Fukushima Medical University,Japan.

Objectives: This study focused on parotid gland tumours diagnosed as benign by fine-needle aspiration cytology and investigated the necessity of frozen section biopsy.

Methods: There were 104 cases of parotid gland tumour where fine-needle aspiration cytology was benign and frozen section biopsy was subsequently performed, between April 2006 and June 2016. In this retrospective study, the results of frozen section biopsy were analysed and compared with the final histological diagnosis. Read More

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http://dx.doi.org/10.1017/S002221511900029XDOI Listing

Necrotizing sialometaplasia can hide the presence of salivary gland tumors: A case series.

Oral Dis 2019 May 5;25(4):1084-1090. Epub 2019 Mar 5.

Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

Objective: Necrotizing sialometaplasia (NS) is an uncommon benign process which affects minor and, more rarely, major salivary glands. While self-limiting, the condition might be clinically and histologically mistaken for malignancy. Furthermore, NS may accompany neoplasms. Read More

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http://doi.wiley.com/10.1111/odi.13066
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http://dx.doi.org/10.1111/odi.13066DOI Listing
May 2019
17 Reads

[Clinicopathological features and possible prognostic factors in parotid lymphomas].

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Feb;51(1):35-42

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

Objective: To investigate the clinicopathological features and prognostic factors in lymphoma of parotid origin.

Methods: Clinicopathological data of the patients with parotid lymphoma who were initially diagnosed in Peking University Hospital of Stomatology from 2006 to 2016 were collected and analyzed retrospectively. The patients were followed-up for 5 to 149 months with a median period of 45 months, and the factors influencing the prognosis were evaluated. Read More

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http://dx.doi.org/10.19723/j.issn.1671-167X.2019.01.007DOI Listing
February 2019
1 Read

Mucoepidermoid carcinoma of the head and neck in children.

Int J Pediatr Otorhinolaryngol 2019 May 10;120:93-99. Epub 2019 Feb 10.

Department of Otolaryngology & Communication Enhancement, Boston Children's Hospital, Boston, MA, 02115, United States; Department of Otolaryngology, Harvard Medical School, Boston, MA, 02115, United States. Electronic address:

Introduction: Mucoepidermoid carcinoma is a rare malignant salivary gland neoplasm in the pediatric population. Few studies have discussed best practice with respect to diagnosis and treatment in children.

Objective: To present our institution's experience with the evaluation and management of pediatric mucoepidermoid carcinoma of the head and neck. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.02.020DOI Listing

Two case reports of synchronous unilateral pleomorphic adenoma and cystadenolymphoma of the parotid gland with literature review.

J Ultrason 2018 ;18(75):369-373

Department of Otorhinolaryngology, Head and Neck Surgery , Klinikum Augsburg, Augsburg , Germany.

Synchronous unilateral tumors in the parotid glands account for less than 5-10% of all salivary gland neoplasms. Mostly these are cystadenolymphomas, but tumors of different histological types can be found as well. In these cases it is often pleomorphic adenoma in combination with cystadenolymphoma. Read More

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http://dx.doi.org/10.15557/JoU.2018.0055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444322PMC
January 2018
1 Read

Spontaneously infarcted parotid tumours: MRI findings.

Dentomaxillofac Radiol 2019 Feb 12:20180382. Epub 2019 Feb 12.

4 Department of Radiology, Osaka University Graduate School of Medicine , Osaka-sayama, Osaka , Japan.

Objectives:: To report MRI findings of spontaneous infarction in parotid tumours.

Methods:: 14 patients (13 male, 1 female; mean age 73 years) with spontaneously infarcted parotid tumours were reviewed retrospectively. MR images were assessed for the location, the presence of synchronous parotid masses, margin characteristics, signal intensity on T and T weighted images, and internal architecture according to the distribution of T signal hyperintensity. Read More

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http://dx.doi.org/10.1259/dmfr.20180382DOI Listing
February 2019

Ectopic pleomorphic adenoma on subcutaneous plane of the cheek.

Arch Craniofac Surg 2019 Feb 1;20(1):55-57. Epub 2019 Feb 1.

Department of Plastic and Reconstructive Surgery, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.

Pleomorphic adenoma is the most common benign tumor of the salivary gland. Pleomorphic adenoma occurs most commonly in the parotid gland but it may involve other salivary gland such as submandible or lingual. We report an ectopic pleomorphic adenoma in the subcutaneous layer of the face. Read More

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http://e-acfs.org/journal/view.php?doi=10.7181/acfs.2018.019
Publisher Site
http://dx.doi.org/10.7181/acfs.2018.01949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411524PMC
February 2019
13 Reads

18F-FDG PET/CT for staging and response assessment of primary parotid MALT lymphoma with multiple sites involvement: A case report.

Medicine (Baltimore) 2019 Feb;98(5):e14270

Department of Nuclear Medicine, Lanzhou University Second Hospital, Lanzhou University.

Rationale: Mucosa-associated lymphoid tissue (MALT) lymphoma is an extranodal low-grade B cell lymphoma that generally exhibits an indolent clinical course. Currently, the application of F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) in MALT lymphoma is still controversial. Herein, we reported a case of using F-FDG PET/CT for staging and response assessment of primary parotid MALT lymphoma with multiple sites involvement. Read More

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http://dx.doi.org/10.1097/MD.0000000000014270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380729PMC
February 2019
14 Reads

Utility of metabolic heterogeneity factor in differentiating malignant versus benign parotid uptake on F FDG PET-CT.

Am J Nucl Med Mol Imaging 2018 20;8(6):415-420. Epub 2018 Dec 20.

Department of Nuclear Medicine and PET, John Hunter and Calvary Mater Hospitals Newcastle NSW, Australia.

Differentiation of benign and malignant parotid uptake on Fluorine 18 Fluro-Deoxy-Glucose Positron Emission Tomography-Computed Tomography (F FDG PET-CT) is of paramount importance due to the poor prognosis of the later but usual quantitative measures such as standardized uptake value (SUV) are not reliable for this purpose. Metabolic heterogeneity, being a characteristic of malignant tumors, would potentially be able to make this distinction. In this study, seventy-one FDG-avid parotid lesions were retrospectively separated histologically into benign and malignant groups. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334206PMC
December 2018

Retrograde parotidectomy under local anesthesia for benign, malignant, and inflammatory lesions.

Am J Otolaryngol 2019 Mar - Apr;40(2):152-155. Epub 2019 Jan 14.

Department of Otolaryngology-Head and Neck Surgery, Stanford University, 801 Welch Road, Stanford, CA, USA 94305. Electronic address:

Objective: To report the patient selection, surgical technique, and outcomes of parotidectomy using local anesthesia under monitored anesthesia care (MAC).

Methods: A retrospective chart review was performed for patients undergoing parotidectomy under local anesthesia at an academic head and neck surgery center.

Results: Six patients deemed high risk for general anesthesia (GA) due to medical comorbidities or with a strong preference to avoid GA underwent parotidectomy using local anesthesia and MAC. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417876PMC
January 2019
2 Reads

Results of cystadenolymphoma treatment of superficial parotid gland.

Otolaryngol Pol 2018 Sep;72(6):23-30

Collegium Medicum Uniwersytetu Mikołaja Kopernika w Toruniu Klinika Otolaryngologii i Laryngologii Onkologicznej z Pododdziałem Audiologii i Foniatrii.

Introduction Warthin's tumor is a non-malignant tumor that occurs in major salivary glands. Diagnostics include an interview and physical examination as well as additional tests - ultrasonography, magnetic resonance tomography, fine-needle aspiration biopsy. Surgical tumor resection remains the method of treatment, the scope of which includes techniques from extracapsular tumor resection to a full range of parotidectomy. Read More

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http://dx.doi.org/10.5604/01.3001.0012.4667DOI Listing
September 2018
3 Reads

[Terebrant basal cell carcinoma].

Pan Afr Med J 2018 30;30:300. Epub 2018 Aug 30.

Service de Dermatologie-Vénérologie, Hôpital d'Instruction Mohammed V, Rabat, Maroc.

Basal cell carcinoma (BCC) is the most frequent skin cancer. It never affects the mucosa. It is characterized by a local malignancy with an extremely rare risk of developing distant metastasis and the lowest mortality. Read More

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http://www.panafrican-med-journal.com/content/article/30/300
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http://dx.doi.org/10.11604/pamj.2018.30.300.16224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320449PMC
January 2019
4 Reads

The diagnostic performance of ultrasonography and computerized tomography in differentiating superficial from deep lobe parotid tumours.

Clin Otolaryngol 2019 Jan 12. Epub 2019 Jan 12.

Department of Otolaryngology Head and Neck Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan (R.O.C.).

Objectives: To validate and compare ultrasound (US) versus computerized tomography (CT) criteria in the localisation of superficial/deep lobe tumours of the parotid gland.

Design And Setting: This was a retrospective study of diagnostic tests performed from January 2008 to June 2017.

Participants: We included adult patients who were referred for a neck ultrasonography examination due to parotid tumours, and who subsequently underwent parotid surgery. Read More

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http://dx.doi.org/10.1111/coa.13289DOI Listing
January 2019
2 Reads

[Clinical pathologic analysis on 3 724 cases of salivary gland tumors].

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Jan;54(1):10-16

Department of Pathology, Hospital of Stomatology, Jilin University, Changchun 130021, China.

To investigate the incidence and proportion of salivary gland tumors in order to provide new thinking for clinical diagnosis and treatment. Collected 3 724 cases salivary gland tumors diagnosed by Pathology Department of Hospital of Stomatology, Jilin University from January 1961 to December 2016. The pathological diagnosis referred to the fourth edition of head and neck-salivary gland tumor histopathological classification standard of WHO. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1002-0098.2019.01.003DOI Listing
January 2019
3 Reads

Contrast-enhanced Multi-detector CT Examination of Parotid Gland Tumors: Determination of the Most Helpful Scanning Delay for Predicting Histologic Subtypes.

J Belg Soc Radiol 2019 Jan 3;103(1). Epub 2019 Jan 3.

Department of Radiology, Ansan Hospital, Korea, University College of Medicine, Ansan, KR.

Purpose: Although contrast-enhanced CT (computed tomography) is regarded as the preoperative imaging modality of choice for parotid gland tumor, scanning methods are highly variable. We aimed at determining the most helpful scanning delay for predicting histologic subtypes of parotid gland tumors.

Material And Methods: Based on the medical record review, we identified 293 patients with 296 parotid gland tumors who underwent uni- or biphasic neck CT examination using a 64-row detector CT with the same acquisition parameters except the scan delays that were: (1) unenhanced, (2) 40 seconds, (3) 50 seconds, and (4) 70 seconds after the beginning of contrast-media injection. Read More

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http://dx.doi.org/10.5334/jbsr.1596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319312PMC
January 2019

Comparative Role of Matrixins in Diagnostics of Parotid Gland Tumors.

Authors:
E V Kochurova

Bull Exp Biol Med 2019 Jan 8;166(3):383-385. Epub 2019 Jan 8.

I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation, Moscow, Russia.

The benign and malignant neoplasms in parotid gland have similar clinical presentations despite different tumor growth rates. The study compared the clinical and morphological data as well as the results of ELISA for MMP-2, MMP-8, MMP-9, TIMP-1, and TIMP-2 in salivary fluid yielded during primary examination of the patients with pleomorphic adenoma and adenocarcinoma of parotid gland. The examined biomarkers detected in salivary fluid in patients with various cancer types differed significantly (p≤0. Read More

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http://dx.doi.org/10.1007/s10517-019-04355-wDOI Listing
January 2019
2 Reads

Parotid incidentalomas on positron emission tomography: what is their clinical significance?

Nucl Med Commun 2019 Mar;40(3):264-269

Norwich Radiology Academy, The Cotman Centre, Norwich.

Objective And Aim: The increased use of PET/CT in cancer staging has resulted in more incidental findings in unexpected locations, making this a challenge for the radiologist interpreting the study. Our aim was to determine the frequency of parotid incidentalomas and to assess the ability of PET/CT to characterize them.

Patients And Methods: At the Norfolk and Norwich University Trust, in between October 2010 to October 2015, 4044 patients had a PET/CT examination. Read More

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http://dx.doi.org/10.1097/MNM.0000000000000961DOI Listing
March 2019
2 Reads

Pediatric follicular lymphoma of the parotid gland.

Arch Craniofac Surg 2018 Dec 27;19(4):279-282. Epub 2018 Dec 27.

Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea.

Primary malignant lymphoma rarely presents as a mass in the salivary gland. It accounts for about 1% of salivary gland tumors. The lymphomas of the parotid gland are mainly non-Hodgkin's lymphoma of B-cell follicular type. Read More

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http://dx.doi.org/10.7181/acfs.2018.02075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325339PMC
December 2018
2 Reads

Intraductal Carcinoma of Salivary Glands Harboring TRIM27-RET Fusion with Mixed Low Grade and Apocrine Types.

Head Neck Pathol 2019 Jan 4. Epub 2019 Jan 4.

Department of Pathology and Laboratory Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, L25, Cleveland, OH, 44195, USA.

Intraductal carcinomas (IDCs) of salivary gland are rare neoplasms. Here, we report a case of IDCs harboring TRIM27-RET fusion with mixed low grade and apocrine types. A 79-year-old male presented with slowly-growing left parotid mass for 2. Read More

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http://link.springer.com/10.1007/s12105-018-0996-1
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http://dx.doi.org/10.1007/s12105-018-0996-1DOI Listing
January 2019
1 Read

Facial Paralysis Following Core Needle Biopsy of a Deep Lobe Parotid Tumor: A Case Report.

Ann Otol Rhinol Laryngol 2019 Apr 2;128(4):357-359. Epub 2019 Jan 2.

1 Department of Surgery, Division of Otolaryngology-Head & Neck Surgery, University of California, San Diego, CA, USA.

Objectives:: To report a case of total facial paralysis as the result of a core needle biopsy.

Methods:: Case report and literature review.

Results:: A 70-year-old man was diagnosed with a deep lobe parotid tumor on computed tomography. Read More

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http://dx.doi.org/10.1177/0003489418820886DOI Listing
April 2019
1 Read

Role of fine-needle aspiration in post liver transplant patients: A clinical/cytological review.

Diagn Cytopathol 2019 May 28;47(5):434-438. Epub 2018 Dec 28.

Department of Pathology, Rush University Medical Center, Chicago, Illinois.

Background: Fine-needle aspiration (FNA) of superficial and deep-seated lesions has been used with high sensitivity and specificity in the diagnosis of neoplastic and nonneoplastic lesions. However, literature of FNA in posttransplant patients is sparse, especially in postliver transplant. We undertook a retrospective study to evaluate the utility of FNA in the clinical management of post liver transplant patients. Read More

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http://dx.doi.org/10.1002/dc.24133DOI Listing
May 2019
1 Read

Vascular interventions in head and neck cancer patients as a marker of poor survival.

J Vasc Surg 2019 01;69(1):181-189

Division of Vascular Surgery, Eastern Virginia Medical School, Norfolk, Va. Electronic address:

Objective: Head and neck cancer can involve the surrounding vasculature and require technically challenging vascular interventions. These interventions can be complicated by tumor invasion, history of prior surgery, and history of radiation therapy. Our aim was to examine patients with vascular interventions in association with head and neck cancer to determine outcomes and best practice. Read More

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http://dx.doi.org/10.1016/j.jvs.2018.04.058DOI Listing
January 2019
2 Reads

Risk of high-grade malignancy in parotid gland tumors as classified by the Milan System for Reporting Salivary Gland Cytopathology.

J Oral Pathol Med 2019 Mar 4;48(3):222-231. Epub 2019 Jan 4.

Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: The Milan System for Reporting Salivary Gland Cytopathology (Milan System) has previously shown its diagnostic utility by categorizing the seven cytology findings in salivary gland lesions. However, there has been lack of study about the risk of high-grade malignancy in the cytology diagnosis based on the Milan System. Thus, we tried to identify the diagnostic ability of the Milan System for high-grade malignancy and to suggest an improved diagnostic approach for preoperative estimation of high-grade malignancy using the Milan System. Read More

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http://dx.doi.org/10.1111/jop.12816DOI Listing

Progression of immunoglobulin G4-related disease to systematic lupus erythematosus after gastric cancer surgery: A case report.

Medicine (Baltimore) 2018 Dec;97(51):e13545

Department of Nephrology, Fujita Health University School of Medicine.

Rationale: Immunoglobulin G4 related disease (IgG4-RD) rarely coexists with other autoimmune diseases, though we had a patient whose primary clinical problem was shifted from IgG4-RD to systemic lupus erythematosus (SLE) after gastrectomy. The present paper aimed to report pathological findings and clinical course of the patient.

Patient Concerns: The patient was a male aged 74 years old with gastric cancer characterized by the following symptoms: Raynaud phenomenon, polyarthralgia, and swollen parotid glands on both sides. Read More

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http://Insights.ovid.com/crossref?an=00005792-201812210-0003
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http://dx.doi.org/10.1097/MD.0000000000013545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320217PMC
December 2018
5 Reads

Bone marrow metastases in salivary duct carcinoma of the parotid gland.

BMJ Case Rep 2018 Dec 3;11(1). Epub 2018 Dec 3.

Department of Otolaryngology/HNS, Louisiana State University Health Sciences Center Shreveport, Shreveport, Louisiana, USA.

Salivary duct carcinoma (SDC) is a rare and extremely aggressive salivary gland cancer. An 81-year-old woman with SDC underwent a total parotidectomy with facial nerve sacrifice and a neck dissection. Following surgery, she was diagnosed with disseminated bone marrow metastases. Read More

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http://dx.doi.org/10.1136/bcr-2018-226636DOI Listing
December 2018
3 Reads

Sebaceous lymphadenoma requiring superficial parotidectomy.

BMJ Case Rep 2018 Nov 28;11(1). Epub 2018 Nov 28.

Department of Surgery, New York Presbyterian Queens, Flushing, New York, USA.

An 82-year-old woman presented with a painless, progressively enlarging right neck mass of 2 years' duration. CT with contrast showed a 5.0 cm confluence of nodes just inferior to the right parotid gland. Read More

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http://www.bmj.com/lookup/doi/10.1136/bcr-2018-224975
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http://dx.doi.org/10.1136/bcr-2018-224975DOI Listing
November 2018
10 Reads

Metachronous bilateral multifocal nodular oncocytic hyperplasia of the parotid gland.

J Stomatol Oral Maxillofac Surg 2018 Dec 16. Epub 2018 Dec 16.

University of Health Sciences, Ankara Application and Research Hospital, Department of Nuclear Medicine, Ankara, Turkey.

Multifocal nodular oncocytic hyperplasia (MNOH) is a rare lesion of the parotid gland and bilateral cases are extremely rare. We report the case of a 69-year-old woman who was operated from MNOH 10 years ago and the bilateralism of the case appeared 10 years later making the case metachronous. Read More

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http://dx.doi.org/10.1016/j.jormas.2018.12.009DOI Listing
December 2018

[Functional parotid surgery for removal of benign parotid tumors].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1810-1812

Department of Stomatology, Tongji Hospital, Tongji University.

To evaluate the effect of the application of functional parotid surgery for removal of benign parotid tumors and the prevention of Frey syndrome. One hundred and fifty-six cases with benign tumor were underwent functional regional parotidectomy. All tumors were smaller than 4 cm in diameter. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.23.010DOI Listing
December 2018
9 Reads

AHNS series: Do you know your guidelines? Diagnosis and management of salivary gland tumors.

Head Neck 2019 Feb 13;41(2):269-280. Epub 2018 Dec 13.

Otolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania.

This article is the next installment of the series "Do you know your guidelines" presented by the Education Committee of the American Head and Neck Society. Guidelines for the workup and management of tumors of the major and minor salivary glands are reviewed. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/hed.25499
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http://dx.doi.org/10.1002/hed.25499DOI Listing
February 2019
12 Reads

Values of fine-needle aspiration cytology of parotid gland tumors: A review of 996 cases at a single institution.

Head Neck 2019 Feb 9;41(2):358-365. Epub 2018 Dec 9.

Department of Pathology, Osaka Medical College, Osaka, Japan.

Background: We evaluated the diagnostic accuracy of fine-needle aspiration cytology (FNAC) in a large series of benign and malignant parotid tumors.

Methods: The FNAC diagnosis of 821 benign and 175 malignant parotid tumors managed at our department between 1999 and 2017 was correlated with the final histology.

Results: FNAC made a correct histopathological diagnosis in 72% of the benign parotid tumors; however, FNAC provided a correct grade in only 34% of the malignant tumors. Read More

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http://dx.doi.org/10.1002/hed.25503DOI Listing
February 2019

[Clinicopathologic and molecular features of myoepithelial tumors of salivary glands].

Zhonghua Bing Li Xue Za Zhi 2018 Dec;47(12):936-940

Department of Pathology, General Hospital of Eastern Theater Command, Nanjing 210002, China.

To investigate the clinicopathological, and molecular characteristics of myoepithelial tumors (MTs) of salivary glands. A total of 37 MTs cases including 13 malignant epithelial tumors (MMTs) and 24 benign epithelial tumors (BMTs) of salivary glands were identified from the archives of the Department of Pathology, General Hospital of Eastern Theater Command, dating from 2006 to 2016. Clinical features, histological patterns, immunohistochemical characteristics and status of EWSR1 gene rearrangement by fluorescence in situ hybridization (FISH) analysis were reviewed in all cases. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2018.12.008DOI Listing
December 2018
2 Reads