5,705 results match your criteria Paraspinal Injections - Facet Joint and Nerve Root Blocks

Reliability of Gradient-Echo Magnetic Resonance Elastography of Lumbar Muscles: Phantom and Clinical Studies.

Diagnostics (Basel) 2022 Jun 3;12(6). Epub 2022 Jun 3.

Department of Medical Imaging, Chi Mei Medical Center, Yongkang, Tainan 71004, Taiwan.

Magnetic resonance elastography (MRE) has been used to successfully characterize the mechanical behavior of healthy and diseased muscles, but no study has been performed to investigate the reliability of MRE on lumbar muscles. The objective of this work was to determine the reliability of MRE techniques on lumbar muscles in both ex vivo phantom and in vivo human studies. In this study, fresh porcine leg muscles were used in the phantom study, and 80 healthy adults (38. Read More

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Paraspinal Muscle Health is Related to Fibrogenic, Adipogenic, and Myogenic Gene Expression in Patients with Lumbar Spine Pathology.

BMC Musculoskelet Disord 2022 Jun 24;23(1):608. Epub 2022 Jun 24.

Department of Orthopaedic Surgery, University of California San Diego, 350 Dickinson Street, Suite 121, Mail Code 8894, San Diego, CA, 92103-8894, USA.

Background: Lumbar spine pathology is a common feature of lower back and/or lower extremity pain and is associated with observable degenerative changes in the lumbar paraspinal muscles that are associated with poor clinical prognosis. Despite the commonly observed phenotype of muscle degeneration in this patient population, its underlying molecular mechanisms are not well understood. The aim of this study was to investigate the relationships between groups of genes within the atrophic, myogenic, fibrogenic, adipogenic, and inflammatory pathways and multifidus muscle health in individuals undergoing surgery for lumbar spine pathology. Read More

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How do Paraspinal Muscles Contract during the Schroth Exercise Treatment in Patients with Adolescent Idiopathic Scoliosis (AIS)?

Bioengineering (Basel) 2022 May 27;9(6). Epub 2022 May 27.

Department of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong SAR 999077, China.

The Schroth exercise can train the paraspinal muscles of patients with adolescent idiopathic scoliosis (AIS), however, muscle performance during the training remains unknown. This study applied surface electromyography (sEMG) to investigate the paraspinal muscle activities before, during and after Schroth exercise in nine AIS patients. This study found that after the Schroth exercise, the paraspinal muscle symmetry index (PMSI) was significantly reduced (PMSI = 1. Read More

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Influence of cross-sectional area and fat infiltration of paraspinal muscles on analgesic efficacy of epidural steroid injection in elderly patients.

Pain Pract 2022 Jun 23. Epub 2022 Jun 23.

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background: An assessment of paraspinal muscle degeneration based on magnetic resonance imaging has been used to investigate both sarcopenia and myosteatosis. The morphologic changes in cross-sectional area and fat infiltration of the paraspinal muscles can affect pain outcomes after epidural steroid injection.

Methods: Patients ≥ 65 years of age who underwent fluoroscopy-guided lumbar epidural steroid injections were enrolled. Read More

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WP1066 induces cell death in a schwannomatosis patient-derived schwannoma cell line.

Cold Spring Harb Mol Case Stud 2022 Jun 22;8(4). Epub 2022 Jun 22.

Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida 32816, USA.

Schwannomatosis is a rare genetic disorder that predisposes individuals to development of multiple schwannomas mainly in spinal and peripheral nerves and to debilitating chronic pain often unrelated to any schwannoma. Pathogenic variants of two genes, and , are causal in familial cases. However, many schwannomatosis patients lack mutations in these genes. Read More

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Biomechanical Properties of Paraspinal Muscles Influence Spinal Loading-A Musculoskeletal Simulation Study.

Front Bioeng Biotechnol 2022 2;10:852201. Epub 2022 Jun 2.

Department of Mechanical Engineering, University of British Columbia, Vancouver, BC, Canada.

Paraspinal muscles are vital to the functioning of the spine. Changes in muscle physiological cross-sectional area significantly affect spinal loading, but the importance of other muscle biomechanical properties remains unclear. This study explored the changes in spinal loading due to variation in five muscle biomechanical properties: passive stiffness, slack sarcomere length (SSL), sarcomere length, specific tension, and pennation angle. Read More

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Association of Paraspinal Muscle CSA and PDFF Measurements With Lumbar Intervertebral Disk Degeneration in Patients With Chronic Low Back Pain.

Front Endocrinol (Lausanne) 2022 26;13:792819. Epub 2022 May 26.

Department of Medical Imaging, the First Affiliated Hospital of Kunming Medical University, Kunming, China.

There is an interaction between the lumbar spine and paraspinal muscles, which may play a role in the development of intervertebral disc (IVD) degeneration and may affect CLBP. The study aims to assess the relationship between IVD degeneration and paraspinal muscle fat infiltration in CLBP patients by quantitative MR imaging, and to evaluate the influence of sex and age on CLBP muscle fat infiltration. Sixty CLBP patients (46. Read More

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Dual microcatheter and coil/balloon pressure cooker technique for transvenous embolization of cerebrospinal fluid-venous fistulas.

J Neurointerv Surg 2022 Jun 15. Epub 2022 Jun 15.

Department of Radiology, Mayo Clinic, Jacksonville, Florida, USA

Cerebrospinal fluid-venous fistula is increasingly recognized as a cause of spontaneous intracranial hypotension.1 Transvenous embolization is emerging as an efficacious minimally invasive treatment.2-4 The procedure aims to embolize paraspinal and foraminal veins draining the fistula; however, complete embolization may be challenging as numerous small venous tributaries at the foraminal venous plexus, including dorsal muscular branches, may serve as additional routes of cerebrospinal fluid egress. Read More

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Spatial distribution of erector spinae activity is related to task-specific pain-related fear during a repetitive object lifting task.

J Electromyogr Kinesiol 2022 Jun 3;65:102678. Epub 2022 Jun 3.

Spinal Movement Biomechanics Group, Division of Physiotherapy, School of Health Professions, Bern University of Applied Sciences, Bern, Switzerland; Faculty of Medicine, University of Basel, Basel, Switzerland. Electronic address:

Fear-avoidance beliefs, particularly the fear of lifting with a flexed spine, are associated with reduced spinal motion during object lifting. Low back pain patients thereby also showed potentially clinically relevant changes in the spatial distribution of back muscle activity, but it remains unknown whether such associations are also present in pain-free individuals. This cross-sectional observational study investigated the relationship between fear-avoidance beliefs and the spatial distribution of lumbar paraspinal muscle activity in pain-free individuals during a repetitive lifting task. Read More

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Potential Pitfall in the Interpretation of Ganglioneuronal Uptake of 18F-PSMA-1007 PET/CT Scans Performed With a High Spatial Resolution Digital PET Scanner.

Clin Nucl Med 2022 Jun 10. Epub 2022 Jun 10.

From the Department of Nuclear Medicine, Royal Brisbane and Women's Hospital.

Abstract: A 69-year-old man with biochemical recurrence of prostate cancer after radical prostatectomy 5 years previously and subsequent salvage radiotherapy to the prostate bed and pelvic nodes underwent PET/CT on a Siemens mCT Flow PET and a second PET/CT 10 months later on a Siemens Vision 600 Digital PET. In addition to a suspicious left hilar lymph node, the new high-resolution PET showed increased visualization and avidity of physiologic uptake in paraspinal and presacral sympathetic ganglia. Caution should be undertaken when interpreting PET/CTs performed on high-resolution digital scanners to avoid mistaking ganglia uptake for metastatic disease. Read More

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Density and Fat Fraction of the Psoas, Paraspinal, and Oblique Muscle Groups are Associated with Lumbar Vertebral Bone Mineral Density in a Multi-Ethnic Community-Living Population: The Multi-Ethnic Study of Atherosclerosis.

J Bone Miner Res 2022 Jun 12. Epub 2022 Jun 12.

Department of Orthopaedic Surgery, School of Medicine, University of California, San Diego, La Jolla, California, USA.

Low vertebral bone mass is a major risk factor for vertebral compression fractures. While sarcopenia has been shown to be associated with low bone mineral density (BMD), it is not known whether trunk musculature is directly associated with lumbar BMD, and whether exercise modifies this association. Using data from the Multi-Ethnic Study of Atherosclerosis (MESA), we sought to determine the association of muscle density and fat fraction of the psoas, paraspinal, and oblique muscle groups with L3 lumbar volumetric BMD, and whether these associations were modified by exercise. Read More

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Imaging characteristics and CT sensitivity for pyogenic spinal infections.

Am J Emerg Med 2022 May 30;58:148-153. Epub 2022 May 30.

Department of Military and Emergency Medicine, Uniformed Services University of Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA; United States Air Force En route Care Research Center, 59th MDW/ST, JBSA-Fort Sam Houston, TX 78234, USA.

Background/objective: Contrast-enhanced magnetic resonance imaging (MRI) is the preferred imaging modality for diagnosing pyogenic spinal infection (PSI), but it is not always available. Our objective was to describe pyogenic spinal infection imaging characteristics in patients presenting to a community emergency department (ED) and estimate the computed tomography (CT) sensitivity for these infections.

Methods: We examined the MRI reports from a cohort of 88 PSI patients whom we enrolled in a prospective cohort study and report the prevalence of each PSI type (spinal epidural abscess/infection, vertebral osteomyelitis/discitis, septic facet, and paravertebral abscess/infection) according to contemporary nomenclature. Read More

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Mature Local Control and Reirradiation Rates Comparing Spine Stereotactic Body Radiotherapy to Conventional Palliative External Beam Radiotherapy.

Int J Radiat Oncol Biol Phys 2022 Jun 5. Epub 2022 Jun 5.

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Purpose: Stereotactic body radiotherapy (SBRT) improves complete pain response for painful spinal metastases compared to conventional external beam radiotherapy (cEBRT). We report mature local control and reirradiation rates in a large cohort of patients treated with SBRT vs. cEBRT enrolled previously in the Canadian Clinical Trials Group Symptom Control (SC). Read More

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Evaluation of Paraspinal Musculature in Small Breed Dogs with and without Atlantoaxial Instability Using Computed Tomography.

Vet Comp Orthop Traumatol 2022 Jun 7. Epub 2022 Jun 7.

Division of Clinical Radiology, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Objective:  The aim of this study was to evaluate differences in paraspinal musculature between dogs with and without atlantoaxial instability (AAI) using computed tomography scans.

Study Design:  Retrospective multicentre study evaluating transverse reconstructed computed tomography scans of 83 small breed dogs (34 with and 49 without AAI) for the cross-sectional paraspinal musculature area at three levels (Occiput/C1, mid-C1, mid-C2). Ratio of moments, dorsal-to-ventral muscle-area ratios (d-v-ratio) and ratios of the dorsal and ventral musculature to C2 height (d-C2-ratio and v-C2-ratio) were evaluated for differences between groups using multivariate analysis of variance ( < 0. Read More

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Cefuroxime concentrations in the anterior and posterior column of the lumbar spine - an experimental porcine study.

Spine J 2022 Jun 4. Epub 2022 Jun 4.

Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark; Aarhus Denmark Microdialysis Research (ADMIRE), Orthopedic Research Laboratory, Aarhus University Hospital, Aarhus N, Denmark; Department of Orthopedic Surgery, Aarhus University Hospital, Aarhus N, Denmark. Electronic address:

Background Context: Surgical site infection following spine surgery is associated with increased morbidity and mortality. Perioperative antibiotic prophylaxis is a key factor in lowering the risk of acquiring an infection. Previous studies have assessed perioperative cefuroxime concentrations in the anterior column of the cervical spine with an anterior surgical approach. Read More

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Natural aging course of lumbar extensor muscle mass and strength in community-dwelling older women: a 1-year prospective observational study.

Aging Clin Exp Res 2022 Jun 6. Epub 2022 Jun 6.

Department of Rehabilitation Medicine, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul, 07061, Republic of Korea.

Background: Although the loss of skeletal limb muscle mass and muscle strength in the elderly have been demonstrated, the aging process of the back muscles to maintain core stability is not well known. This 1-year prospective observational study aimed to investigate the natural aging course of the lumbar extensor muscles (LEMs) compared with the extremity muscles and determine whether muscle strength or mass decreases more in community-dwelling older women.

Methods: Twenty-four older urban-dwelling women aged 70 years or older were initially enrolled. Read More

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Deviation from consensus contouring guidelines predicts inferior local control after spine stereotactic body radiotherapy.

Radiother Oncol 2022 Jun 3;173:215-222. Epub 2022 Jun 3.

Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, United States. Electronic address:

Background And Purpose: To analyze the impact of target delineation on local control (LC) after stereotactic body radiotherapy (SBRT) for spine metastasis.

Materials And Methods: Patients with de novo metastasis of the spine treated with SBRT, excluding those with prostate or hematologic malignancies, were retrospectively reviewed. Deviations from consensus contouring guidelines included incomplete coverage of involved vertebral compartments, omission of adjacent compartments, or unnecessary circumferential coverage. Read More

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Spinal myxomas: review of a rare entity.

J Surg Case Rep 2022 May 31;2022(5):rjac221. Epub 2022 May 31.

King's Neuro Lab, Department of Neurosurgery, King's College Hospital NHS Foundation Trust, London, UK.

Intramuscular myxomas are rare, benign mesenchymal tumours, occurring predominantly in large skeletal muscles as large, slow-growing and painless masses. Spinal occurrence is rare, and may present incidentally, or diagnosed via localized symptoms secondary to local infiltration of surrounding structures. Differential diagnosis based on imaging includes sarcomas, meningiomas and lipomas. Read More

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The Pain Intensity/Quality and Pain Site Association with Muscle Activity and Muscle Activity Distribution in Patients with Chronic Low Back Pain: Using a Generalized Linear Mixed Model Analysis.

Pain Res Manag 2022 25;2022:5751204. Epub 2022 May 25.

Neurorehabilitation Research Center, Kio University, Nara, Japan.

Background: Pain can alter muscle activity, although it is not clear how pain intensity and site location affect muscle activity. This study aimed to reveal the complex associations among the pain site, pain intensity/quality, muscle activity, and muscle activity distribution.

Methods: Electromyographic signals were recorded from above a bilateral lumbar erector spinae muscle with a four-channel electrode in 23 patients with chronic low back pain while they performed a lumbar bending and returning task. Read More

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Quantitative single photon emission computed tomography derived standardized uptake values on 99mTc-PYP scan in patients with suspected ATTR cardiac amyloidosis.

J Nucl Cardiol 2022 Jun 2. Epub 2022 Jun 2.

Heart and Vascular Institute, West Virginia University, 1 Medical Center Dr, Morgantown, WV, 26506, USA.

Technetium-99 pyrophosphate scintigraphy (99mTc-PYP) provides qualitative and semiquantitative diagnosis of ATTR cardiac amyloidosis (ATTR-CA) using the Perugini scoring system and heart/contralateral heart ratio (H/CL) on planar imaging. Standardized uptake values (SUV) with quantitative single photon emission computed tomography (xSPECT/CT) can offer superior diagnostic accuracy and quantification through precise myocardial contouring that enhances assessment of ATTR-CA burden. We examined the correlation of xSPECT/CT SUVs with Perugini score and H/CL ratio. Read More

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Effect of sampling position in fresh, dry-aged and wet-aged beef from M. Longissimus dorsi of Simmental cattle analyzed by H NMR spectroscopy.

Food Res Int 2022 Jun 4;156:111334. Epub 2022 May 4.

Department of Food Material Science, Institute of Food Science and Biotechnology, University of Hohenheim, Garbenstr. 25, 70599 Stuttgart, Germany. Electronic address:

The aging of beef affects the metabolome and, thus, its quality, such as taste or tenderness. In addition to the aging method, intrinsic factors, such as breed, feed and muscle type, also have an effect on beef's metabolome. It is not known yet whether the position of the sampling in large muscles also has an influence on beef's metabolome and its aging outcome. Read More

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Utility of Wavelet Denoising with Geometry Factor Weighting for Gadoxetic Acid-enhanced Hepatobiliary-phase MR Imaging.

Magn Reson Med Sci 2022 Jun 1. Epub 2022 Jun 1.

Department of Diagnostic Radiology, Hiroshima University.

Purpose: The wavelet denoising with geometry factor weighting (g-denoising) method can reduce the image noise by adapting to spatially varying noise levels induced by parallel imaging. The aim of this study was to investigate the clinical applicability of g-denoising on hepatobiliary-phase (HBP) images with gadoxetic acid.

Methods: We subjected 53 patients suspected of harboring hepatic neoplastic lesions to gadoxetic acid-enhanced HBP imaging with and without g-denoising (gHBP and gHBP). Read More

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Correlation between the fatty infiltration of paraspinal muscles and disc degeneration and the underlying mechanism.

BMC Musculoskelet Disord 2022 May 30;23(1):509. Epub 2022 May 30.

Department of Orthopedics, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, China.

Background: Low back pain (LBP) is associated with lumbar disc degeneration (LDD) and fatty infiltration of paraspinal muscles. However, there are some controversies about the relationship between LDD and fatty infiltration of paraspinal muscles, and the causation of them is also not clear. Thus, we investigated whether the degree of LDD was associated with fatty infiltration of paraspinal muscles and preliminarily explored the underlying mechanism. Read More

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Comparison of compensatory lumbar movement in participants with and without non-specific chronic low back pain: A cross-sectional study.

J Back Musculoskelet Rehabil 2022 May 18. Epub 2022 May 18.

Department of Physical Therapy, College of Health Sciences, Kyung-Nam University, Changwon-si, Korea.

Background: Many studies have compared muscle length and muscle activity for low back pain. However, compensatory movement for non-specific low back pain has not yet been studied sufficiently.

Objective: The purpose of this study was to compare the length of the hip flexor, lumbar extensor endurance and the muscle activity of the erector spinae and gluteus maximus during hip extension, and the compensatory movement of the lumbar in people with or without nonspecific chronic low back pain. Read More

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Associations of Lumber Disc Degeneration With Paraspinal Muscles Myosteatosis in Discogenic Low Back Pain.

Front Endocrinol (Lausanne) 2022 13;13:891088. Epub 2022 May 13.

Department of Medical Imaging, The First Affiliated Hospital of Kunming Medical University, Kunming, China.

Accompanied with intervertebral disc (IVD) degeneration, increasing fat infiltration of paraspinal muscles may be related to discogenic low back pain (DLBP), but their relationship is still unclear and the classical animal models are not completely applicable. The purpose of this study was to assess the paraspinal muscle fat infiltration in patients with DLBP by quantitative MRI, and to develop a novel DLBP rat model to explore the potential relationship between DLBP paraspinal muscle fat infiltration and TNF-α levels. We measured the proton density fat fraction (PDFF) of the multifidus and erector spinae muscles of 70 DLBP patients and 36 healthy volunteers by using quantitative MRI IDEAL-IQ. Read More

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The effect of ageing on fat infiltration of thigh and paraspinal muscles in men.

Aging Clin Exp Res 2022 May 28. Epub 2022 May 28.

Institute of Medical Physics (IMP), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Henkestr. 91, 91052, Erlangen, Germany.

Background: Myosteatosis, skeletal muscle fat infiltration, is associated with inflammation and fibrosis. The age-related increase of myosteatosis is an important characteristic of sarcopenia and contributes to fragility.

Aims: To investigate the impact of healthy aging on intermuscular adipose tissue (IMAT) and muscle fat fraction (FF) in the thigh and the paraspinal muscles in males. Read More

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Prevention of Compression Fracture in Osteoporosis Patients under Minimally Invasive Trans-Foraminal Lumbar Interbody Fusion with Assistance of Bone-Mounted Robotic System in Two-Level Degenerative Lumbar Disease.

Medicina (Kaunas) 2022 May 23;58(5). Epub 2022 May 23.

Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

Minimally invasive spine surgery reduces destruction of the paraspinal musculature and improves spinal stability. Nevertheless, screw loosening remains a challenging issue in osteoporosis patients receiving spinal fixation and fusion surgery. Moreover, adjacent vertebral compression fracture is a major complication, particularly in patients with osteoporosis. Read More

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A Severe Systemic Infection in a 14-Year-Old Boy That Took Place during the COVID-19 Pandemic.

Children (Basel) 2022 May 15;9(5). Epub 2022 May 15.

Department of Pediatrics, Allergology and Gastroenterology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 87-100 Toruń, Poland.

Introduction: Since March 2020, the COVID-19 pandemic has been a global talking point. Access to health care has become more difficult, and such an obstacle increase the risk of inadequate medical care, especially among paediatric patients.

Case: This report describes the case of a previously healthy teenager who was staying home for 2 months due to a strict lockdown period in the COVID-19 pandemic and was admitted to hospital for fever, nausea and lumbar pain. Read More

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Histopathological and Immunohistochemical Evaluation of Canine Nerve Sheath Tumors and Proposal for an Updated Classification.

Vet Sci 2022 Apr 22;9(5). Epub 2022 Apr 22.

Department of Veterinary Science, University of Pisa, 56124 Pisa, Italy.

Nerve sheath tumors are a group of tumors originating from Schwann cells, fibroblasts, and perineurial cells. In veterinary pathology, the terminology for nerve sheath tumors remains inconsistent, and many pathologists follow the human classification of such tumors in practice. Immunohistochemistry plays an important role in the diagnosis of nerve sheath tumors, but specific immunohistochemical and molecular biomarkers are lacking. Read More

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Clinical Evaluation of Paraspinal Mini-Tubular Lumbar Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion for Lumbar Spondylolisthesis Grade I with Lumbar Spinal Stenosis: A Cohort Study.

Front Surg 2022 10;9:906289. Epub 2022 May 10.

Department of Neurosurgery, Fujian Medical University Union Hospital, Fuzhou, China.

Objective: To investigate the clinical outcome data and difference in efficacy between paraspinal mini-tubular lumbar decompression (PMTD) and minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) in the treatment of degenerative lumbar spondylolisthesis grade I with lumbar spinal stenosis (DLS-I-LSS).

Methods: Patients with DLS-I-LSS, who underwent PMTD or MIS TLIF from September 2017 to March 2020, were included retrospectively. The follow-up period was 24 months after surgery. Read More

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