Search Our Scientific Publications & Authors

Brain Behav 2019 Feb 15:e01230. Epub 2019 Feb 15.

Department of Biomedical and NeuroMotor Sciences (DiBiNeM), University of Bologna, Bologna, Italy.

Objectives: To investigate the prevalence of REM sleep behavior disorder (RBD) in patients with inflammatory arthritis (IA) to ascertain if RBD could be an internal red flag signaling a fluctuating state of inflammation based on the theory of "protoconsciousness".

Materials & Methods: One hundred and three patients with a confirmed diagnosis of IA were consecutively recruited. The patients underwent general (IA activity, functional status, laboratory tests) and neurological evaluations. Read More

J Neurol 2019 Feb 11. Epub 2019 Feb 11.

Department of Neurology, Washington University School of Medicine, Saint Louis, MO, USA.

Objectives: Autoimmune encephalitis (AE) is increasingly recognized as an important cause of subacute cognitive decline, seizures, and encephalopathy, with an ever-broadening clinical phenotype. Sleep disturbances are reported in AE patients, including rapid eye movement sleep behavior disorder, hypersomnia, fragmented sleep, and sleep-disordered breathing; however, the prevalence of sleep disturbances and contributions to outcomes in AE patients remain unknown. There is a need to determine the prevalence of sleep disturbances in AE patients, and to clarify the relationship between specific autoantibodies and disruptions in sleep. Read More

J Clin Sleep Med 2019 Feb 4. Epub 2019 Feb 4.

Abstract: The most common sleep disorders that can result in injurious or violent behaviors include REM sleep behavioral disorder, sleepwalking, comorbid parasomnias, sleep-related dissociative disorder, and obstructive sleep apnea. Video polysomnography is usually indicated to evaluate recurring sleep-related injury in adults. Only one-third of patients with complex paroxysmal nocturnal events will have one of their habitual events on a single night of in-laboratory video polysomnography, most often those who have prominent, high-frequency motor features. Read More

J Clin Sleep Med 2019 Feb 4. Epub 2019 Feb 4.

Study Objectives: Growing evidence suggests that nightmares have considerable adverse effects on waking behavior, possibly by increasing post-sleep negative emotions. Dysphoric reactions to nightmares are one component of nightmare severity for which the neural correlates are unknown. Here, we investigate possible neural correlates of nightmare severity in a sample of individuals who frequently recall nightmares. Read More

Clin Neuropharmacol 2019 Feb 1. Epub 2019 Feb 1.

Departments of Family Medicine and.

Background: Non-rapid-eye-movement (NREM) parasomnias are disorders of sleep ranging from confusional arousals to sleepwalking and sleep-related eating disorders. Historically, antidepressants and benzodiazepines were recommended in treatment of NREM parasomnias. In this case report, we are reporting the use of buspirone in a patient with NREM parasomnias, which produced substantial resolution of symptoms. Read More

J Sleep Res 2019 Jan 29:e12820. Epub 2019 Jan 29.

Department of Clinical Psychology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

This consensus paper provides an overview of the state of the art in research on the aetiology and treatment of nightmare disorder and outlines further perspectives on these issues. It presents a definition of nightmares and nightmare disorder followed by epidemiological findings, and then explains existing models of nightmare aetiology in traumatized and non-traumatized individuals. Chronic nightmares develop through the interaction of elevated hyperarousal and impaired fear extinction. Read More

Soc Dev 2018 Nov 26;27(4):967-983. Epub 2018 Apr 26.

Arizona State University.

Children's sleep has both environmental and genetic influences, with stressful family environmental factors like household chaos and marital conflict associated with sleep duration and quality (El-Sheikh, Buckhalt, Mize, & Acebo, 2006; Fiese, Winter, Sliwinski, & Anbar, 2007). However, it is less clear whether sibling conflict is related to sleep duration and children's sleep problems (e.g. Read More

Mo Med 2018 Nov-Dec;115(6):527-532

Madihah Hepburn, MD, Pradeep C. Bollu, MD, Pradeep Sahota, MD, MSMA member since 2003, and Brandi French, MD, are in the Department of Neurology, University of Missouri - Columbia.

Cerebrovascular disease encompassing both ischemic and hemorrhagic strokes are among the leading causes of disability and mortality globally. The current evidence strongly suggests that identifying and addressing sleep disorders should be a part of both primary and secondary stroke prevention. Stroke and sleep are 'bedfellows' since sleep disorders, including sleep-disordered breathing, parasomnias, sleep-related movement disorders, insomnia, and hypersomnia are intimately intertwined with co-morbid cardiovascular conditions and increase stroke risk. Read More

BMC Neurol 2019 Jan 11;19(1). Epub 2019 Jan 11.

Department of Neurology, University of Yamanashi, 1110 Shimokatou, Yamanashi, 409-3898, Japan.

Background: Spinocerebellar ataxia type 31 (SCA 31) is a slowly progressive neurodegenerative disorder characterized by pure cerebellar ataxia. Unlike other CAG repeat diseases, sleep-related problems have not been reported in patients with SCA 31 so far.

Case Presentation: A 67-year-old woman was admitted to our hospital with dysarthria and gait disturbance after onset age of 62 years. Read More

Zhonghua Nei Ke Za Zhi 2019 Jan;58(1):17-26

Stroke-related sleep disorders (SSD) are common symptoms after stroke, which are common but easily ignored. Studies have shown that sleep disorders in stroke patients would have negative impact on prognosis. However, there is still a lack of consensus and guidance on SSD evaluation and management worldwide. Read More

Schizophr Res 2018 Dec 14. Epub 2018 Dec 14.

Department of Child and Adolescent Psychiatry, Erasmus University Medical Centre-Sophia Children's Hospital, Rotterdam, the Netherlands; Department of Social and Behavioral Science, Harvard TH Chan School of Public Health, Boston, USA. Electronic address:

Background: Psychotic experiences comprise auditory and visual perceptive phenomena, such as hearing or seeing things that are not there, in the absence of a psychotic disorder. Psychotic experiences commonly occur in the general pediatric population. Although the majority of psychotic experiences are transient, they are predictive of future psychotic and non-psychotic disorders. Read More

Pediatr Ann 2018 Dec;47(12):e504-e506

Restless legs syndrome (RLS) is a common pediatric condition that often goes undiagnosed. The genetics and pathophysiology of this sensorimotor condition are still not well understood. RLS can affect any part of the body, but the thighs and calves are the most commonly affected. Read More

Tuberk Toraks 2018 Sep;66(3):217-223

Department of Chest Diseases, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.

Introduction: We aimed to investigate the relationship between frequency of restless legs syndrome (RLS), depression, anxiety and sleep quality among medical school students.

Materials And Methods: We applied a questionnaire to medical school students. This questionnaire includes some questions about demographic features of participants, questions related with RLS diagnosis, the pittsburgh sleep quality index (PSQI), beck-depression-scale (BDS), beck-anxiety scale (BAS) to all subjects. Read More

Sleep 2018 Nov 26. Epub 2018 Nov 26.

Minnesota Regional Sleep Disorders Center, Departments of Psychiatry, Hennepin County Medical Center and University of Minnesota Medical School, Minneapolis, MN, USA.

Study Objectives: Complex sexual behavior during sleep (CSBS) is a well described clinical entity in NREM sleep parasomnias (i.e. sexsomnia). Read More

Cureus 2018 Sep 22;10(9):e3345. Epub 2018 Sep 22.

Neurology, University of Missouri, Columbia, USA.

Sleep disorders constitute a major aspect of the non-motor symptoms of Parkinson's disease (PD). Rapid eye movement (REM) behavior disorders are the most frequently experienced parasomnias in patients with PD. Non-REM sleep disorders like confusional arousals, sleep terrors, sleepwalking, and sleep-related eating disorder (SRED) are also associated with PD. Read More

Curr Biol 2018 Nov 19;28(22):R1288-R1289. Epub 2018 Nov 19.

Institut du Cerveau et de la Moelle, Sorbonne University, Pitié Salpêtrière Hospital, Paris, France. Electronic address:

Arnulf describes the fascinating behavior of sleepwalking and its associated parasomnias. Read More

Handb Exp Pharmacol 2018 Nov 16. Epub 2018 Nov 16.

Wisconsin Institute for Sleep and Consciousness, University of Wisconsin Madison, Madison, WI, USA.

Sleep and wakefulness are highly complex processes that are elegantly orchestrated by fine-tuned neurochemical changes among neuronal and non-neuronal ensembles, nuclei, and networks of the brain. Important neurotransmitters and neuromodulators regulating the circadian and homeostatic facets of sleep-wake physiology include melatonin, γ-aminobutyric acid, hypocretin, histamine, norepinephrine, serotonin, dopamine, and adenosine. Dysregulation of these neurochemical systems may cause sleep-wake disorders, which are commonly classified into insomnia disorder, parasomnias, circadian rhythm sleep-wake disorders, central disorders of hypersomnolence, sleep-related movement disorders, and sleep-related breathing disorders. Read More

Sleep Med 2019 Jan 29;53:28-34. Epub 2018 Sep 29.

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada. Electronic address:

Objectives: To examine associations between parent-reported child sleep walking or talking, nightmares, and trouble sleeping at age eight and psychiatric problems in adulthood (age 30-35) in extremely low birth weight (ELBW; <1000 g) survivors and matched normal birth weight (NBW; >2500 g) control participants.

Methods: At age eight, parents of ELBW survivors and NBW control participants completed sleep items on the Child Behavior Checklist assessing the presence of sleep walking/talking, nightmares, or trouble sleeping. At age 30-35, 98 ELBW and 94 NBW individuals completed the Mini International Neuropsychiatric Interview (MINI), Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI). Read More

Sleep Med Clin 2018 Dec 26;13(4):571-582. Epub 2018 Sep 26.

Center for Advanced Research in Sleep Medicine, Höpital du Sacré-Cœur de Montréal, 5400 Boulevard Gouin Ouest, Montréal, Québec H4J 1C5, Canada.

The aim of this article is to introduce transcranial magnetic stimulation (TMS) to dental practitioners and to explain its use in obstructive sleep apnea (OSA) and sleep bruxism (SB). In these 2 sleep disorders, TMS has proven to be a useful tool to explore pathophysiological pathways and disease mechanisms, and in a more limited way, to recruit upper airway muscles in OSA and reduce muscle activity and pain intensity in SB. Although promising, research using TMS in these conditions is still very limited and future investigations should be conducted before its clinical application can be considered. Read More

Am J Orthod Dentofacial Orthop 2018 Nov;154(5):718-732

Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan. Electronic address:

Prader-Willi syndrome (PWS) is a complex disorder that affects multiple systems and may cause craniofacial and dentofacial abnormalities. However, there is still a lack of evidence in the literature regarding the progress of orthodontic treatment in patients with PWS. This case report describes the successful orthodontic treatment of a patient with PWS. Read More

Nat Sci Sleep 2018 10;10:317-326. Epub 2018 Oct 10.

"Claudio Munari" Center for Epilepsy Surgery, Niguarda Hospital, Milan, Italy,

Sleep-related hypermotor epilepsy (SHE), previously called nocturnal frontal lobe epilepsy (NFLE), is a focal epilepsy characterized by asymmetric tonic/dystonic posturing and/or complex hyperkinetic seizures occurring mostly during sleep. SHE fulfills the definition of rare disease with an estimated minimum prevalence of 1.8/100,000 individuals, and it represents about 10% of drug-resistant surgical cases. Read More

Oxid Med Cell Longev 2018;2018:7612172. Epub 2018 Sep 18.

Graduation Program in Biochemistry, Federal Pampa University, Uruguaiana, RS, Brazil.

J Vet Intern Med 2018 Nov 12;32(6):2029-2036. Epub 2018 Oct 12.

Neurology Department, Queen Mother Hospital for Animals, Royal Veterinary College, London, United Kingdom.

Background: Abnormal sleep behavior has been reported in 5 dogs during recovery from tetanus.

Hypothesis: REM sleep behavior disorder (RBD) is a more common consequence of tetanus than previously reported in veterinary literature and easily confused for epileptic seizures.

Animals: Sixty-one client-owned dogs diagnosed with tetanus at 2 UK referral centers. Read More

J Clin Neurosci 2019 Jan 9;59:254-258. Epub 2018 Oct 9.

Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address:

The current study aimed to investigate the occurrence and clinical associations of rapid eye movement (REM) behavior disorder (RBD) in early-stage Parkinson's disease (PD) from a cohort of Chinese patients. 158 treatment-naive PD patients in total were enrolled in the study. Each patient was categorized as PD with or without RBD according to the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire (RBDSQ). Read More

J Sleep Res 2018 Oct 8:e12772. Epub 2018 Oct 8.

Sleep Disorders Centre, Guy's Hospital, London, UK.

Although video polysomnography (vPSG) is not routinely recommended for the evaluation of typical cases of non-rapid eye movement (NREM) parasomnias, it can aid diagnosis of unusual cases, other sleep disorders and complicated cases with REM behaviour disorder (RBD), and in differentiating parasomnias from epilepsy. In this study, we aimed to assess vPSG findings in consecutive patients with a clinical diagnosis of NREM-parasomnia covering the whole phenotypic spectrum. Five hundred and twelve patients with a final diagnosis of NREM parasomnia who had undergone vPSG were retrospectively identified. Read More

Am J Med 2018 Oct 4. Epub 2018 Oct 4.

Department of Neurology, Brigham and Women's Hospital, Boston, Mass.

Sleep disorders are frequent and can have serious consequences on patients' health and quality of life. While some sleep disorders are more challenging to treat, most can be easily managed with adequate interventions. We review the main diagnostic features of 6 major sleep disorders (insomnia, circadian rhythm disorders, sleep-disordered breathing, hypersomnia/narcolepsy, parasomnias, and restless legs syndrome/periodic limb movement disorder) to aid medical practitioners in screening and treating sleep disorders as part of clinical practice. Read More

Psychopharmacology (Berl) 2018 Nov 5;235(11):3083-3091. Epub 2018 Oct 5.

Department of Psychiatry and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.

Sleep paralysis is a state of involuntary immobility occurring at sleep onset or offset, often accompanied by uncanny "ghost-like" hallucinations and extreme fear reactions. I provide here a neuropharmacological account for these hallucinatory experiences by evoking the role of the serotonin 2A receptor (5-HTR). Research has shown that 5-HTR activation can induce visual hallucinations, "mystical" subjective states, and out-of-body experiences (OBEs), and modulate fear circuits. Read More

Rinsho Shinkeigaku 2018 Oct 29;58(10):617-621. Epub 2018 Sep 29.

Department of Neurology, Dokkyo Medical University.

A 57-year-old woman had been suffered from insomnia due to restlessness and abnormal sensation of the left side of the body for 33 years. Since the preceding year of the first visit frequency of the symptoms increased, and the abnormal sensation was spread to the right leg. Her daughter had restless legs syndrome (RLS) since age 20. Read More

Nihon Eiseigaku Zasshi 2018 ;73(3):365-372

Graduate School of Health and Nursing Science, Wakayama Medical University.

Objectives: In this study, we examined whether a combined regimen of a short-term nap and a light physical exercise is effective in improving sleep among elderly individuals with mild-to-moderate dementia in communal living group homes.

Methods: Twenty-three female residents (aged 87.4±5. Read More

Mo Med 2018 Mar-Apr;115(2):169-175

Pradeep C. Bollu, MD, Munish K. Goyal, MD, Mahesh Thakkar, PhD, and Pradeep Sahota, MD, MSMA member since 2003, are in the Department of Neurology, University of Missouri - Columbia.

Parasomnias are abnormal and undesirable behaviors during sleep and are thought to be due to the sleep state instability. Some of them are benign, while some of them point to a possible underlying neurodegenerative process. This article briefly discusses the clinical characteristics, demographics, and pathophysiology of major parasomnias and associated disorders. Read More

Neurophysiol Clin 2018 Oct 15;48(5):277-286. Epub 2018 Sep 15.

NeuroPain Team, Inserm U 1028/CNRS, UMR 5292, University of Lyon, Lyon Neuroscience Research Centre (CRNL), 69677 Bron, France.

Objective: Differential diagnosis between sleep-related epileptic seizures and NREM parasomnia remains challenging. Pathophysiological markers to differentiate both conditions are needed. Activation of autonomic system is present in arousal reactions and epileptic seizures. Read More

Workplace Health Saf 2018 Sep 17:2165079918785392. Epub 2018 Sep 17.

10 Manisa Celal Bayar University.

Sleep problems may have negative effects on work-life balance, overall health, and safety. We aimed to investigate the association between sleep disorders and absenteeism and delay to work (being late or tardy) among the working adult population. The study was conducted by using data from a large survey of working adults who participated in the Turkish Adult Population Epidemiology of Sleep Study (TAPES) managed by Turkish Sleep Medicine Society (TSMS). Read More

Dent Clin North Am 2018 Oct 14;62(4):657-663. Epub 2018 Aug 14.

Section of Orofacial Pain and Jaw Function, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark; Scandinavian Center for Orofacial Neurosciences (SCON).

Bruxism is an oral behavior that may lead to repetitive jaw-muscle activity characterized by clenching or grinding of the teeth and/or by bracing or thrusting of the mandible with 2 distinct circadian manifestations: sleep bruxism or awake bruxism. They share common risk factors and lead to similar consequences for the masticatory system but may have different etiology and pathophysiology. This oral behavior has been associated with tooth wear, masticatory muscle tenderness, headaches, and painful temporomandibular disorders. Read More

J Clin Med 2018 Aug 23;7(9). Epub 2018 Aug 23.

Department of Experimental Dentistry, Wroclaw Medical University, 50-367 Wroclaw, Poland.

Background: Sleep sex also known as sexsomnia or somnambulistic sexual behavior is proposed to be classified as NREM (non-rapid eye movement) parasomnia (as a clinical subtype of disorders of arousal from NREM sleep-primarily confusional arousals or less commonly sleepwalking), but it has also been described in relation to REM (rapid eye movement) parasomnias.

Methods: The authors searched the PubMed database to identify relevant publications and present the co-occurrence of sexsomnia and other sleep disorders as a non-systematic review with case series.

Results: In the available literature the comorbidity of sexsomnia and other sleep disorders were reported mainly in case reports and less in case series. Read More

Neurol Sci 2018 Nov 17;39(11):1927-1934. Epub 2018 Aug 17.

Department of Geriatric Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, 650032, Yunnan, People's Republic of China.

Objective: Recent studies have shown an association between migraine and restless legs syndrome (RLS), but RLS prevalence among individuals with migraine differs substantially across studies. The present work aimed to comprehensively assess available evidence to estimate RLS prevalence among individuals with migraine and non-migraine controls.

Method: Web of Science, PubMed, Embase, Chinese National Knowledge Infrastructure, Wanfang, and SinoMed databases were searched for observational and case-control studies of RLS prevalence among individuals with migraine. Read More

Saudi Med J 2018 Aug;39(8):792-798

Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Hitit University, Corum, Turkey. E-mail.

Objective: To determine the prevalence of restless legs syndrome (RLS) in patients with chronic renal failure (CRF) and to compare CRF patients with or without RLS in terms fatigue and sleep quality.

Methods: A cross-sectional study was conducted on 220 patients (18-75 years) who were undergoing dialysis 3 times weekly in Çorum Province, Corum, Turkey, between January 2014 and January 2016. The diagnosis of RLS was based on the diagnostic form proposed by the international RLS study group. Read More

Neurol Sci 2018 Dec 13;39(12):2217-2220. Epub 2018 Aug 13.

Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, No 6, Shuangyong Road, Nanning, Guangxi, China.

Turk J Pediatr 2018 ;60(1):70-75

Department of Pediatric Gastroenterology, Pamukkale University, Faculty of Medicine, Denizli, Turkey.

Işıkay S, Işıkay N, Per H, Çarman KB, Kocamaz H. Restless leg syndrome in children with celiac disease. Turk J Pediatr 2018; 60: 70-75. Read More

Nurs Clin North Am 2018 09;53(3):433-445

Duke University School of Nursing, 307 Trent Drive, DUMC Box 3322, Durham, NC 27710, USA. Electronic address:

Restless legs syndrome/Willis-Ekbon disease (RLS/WED) is a common sensorimotor disorder characterized by an irresistible urge to move and is associated with an uncomfortable sensation typically in the lower extremities. Dopaminergic neurotransmission abnormalities, genetics, sleep deprivation, and iron deficiency all play key roles in the pathogenesis of primary RLS. Secondary RLS has been associated with other medical conditions and medication usage. Read More

Sleep Med Clin 2018 Sep;13(3):335-348

Sleep and Epilepsy Center, Neurocenter of Southern Switzerland, Civic Hospital of Lugano (EOC), Via Tesserete 46, Lugano CH-6903, Switzerland.

Restless legs syndrome/Willis-Ekbom disease is a common disorder during pregnancy that may significantly impact on the health of affected women, leading to negative consequences in the short and long term. An accurate diagnosis helps to recognize the syndrome and choose the optimal therapeutic strategy, based on the characteristics and needs of the patient. This article summarizes the main treatment options recommended by the consensus clinical guidelines of the International Restless Legs Syndrome Study Group and provides a short guide to the management of restless leg syndrome during pregnancy in clinical practice. Read More

Headache 2018 Jul 8;58(7):1030-1039. Epub 2018 Aug 8.

Montefiore Headache Center, Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.

Migraine shares a complex and poorly understood relationship with sleep. Patients consistently report poor sleep prior to migraine attacks and during them, identifying poor sleep as a migraine trigger. However, anecdotally, sleep is reported to serve a therapeutic role in terminating headache. Read More

Rev Neurol (Paris) 2018 Sep - Oct;174(7-8):522-531. Epub 2018 Jul 31.

Clinical Neurophysiology Department, Clinical Neurosciences Pole, Bordeaux Teaching Hospital, 33076 Bordeaux, France; Bordeaux University, Aquitaine Institute of Cognitive and Integrative Neurosciences, UMR5287, 33076 Bordeaux, France; CNRS, Aquitaine Institute of Cognitive and Integrative Neurosciences, UMR 5287, 33076 Bordeaux, France.

Dopaminergic agonists, α2δ ligands and opioids are, as single-drug therapy, the first line treatment for restless legs syndrome (RLS/Willis-Ekbom disease). However, despite treatment efficacy, exacerbations of RLS may occur with overall worsening in symptoms severity, development of pain and symptoms spreading to other parts of the body, without meeting augmentation syndrome criteria. This development of "drug-resistant" RLS can cause pain, severe insomnia and psychiatric disorders that affect considerably patients' quality of life. Read More

J Craniofac Surg 2018 Sep;29(6):1505-1508

Bauru School of Dentistry and the Hospital for Rehabilitation of Craniofacial Anomalies.

The temporomandibular disorders (TMDs) and sleep bruxism (SB) affect the quality of life (QoL) of the individuals in general. However, the literature lacks studies on individuals with cleft lip and palate (CLP). Thus, this study aimed to evaluate the impact of TMD and SB on the oral health-related quality of life (OHRQoL) of individuals with CLP. Read More

J Psychosoc Nurs Ment Health Serv 2018 Aug;56(8):11-14

Sleep terrors, one of the non-rapid eye movement parasomnias, are interesting nighttime phenomena that can be distressing for parents. For most children, this behavior is temporary and does not cause significant problems. However, some psychiatric conditions may have a higher prevalence of parasomnias, including sleep terrors. Read More

J Adolesc 2018 Oct 29;68:87-93. Epub 2018 Jul 29.

National Jewish Health, USA.

Introduction: Involvement in bullying is associated with negative health outcomes for adolescents. Recent studies suggest that bullying is related to sleep disturbances. The purpose of this study was to examine differences in sleep disturbances (bedtime fears, insomnia, parasomnias) between victims, bullies, and youth not involved in bullying, as well as to explore differences across various types of bullying behavior (verbal, physical, social, cyber). Read More

Curr Pain Headache Rep 2018 Jul 30;22(10):63. Epub 2018 Jul 30.

Jefferson Headache Center, 900 Walnut Street, Suite, Philadelphia, PA, 200, USA.

Purpose Of Review: To explain our current understanding of exploding head syndrome (EHS), an unusual and underreported sensory parasomnia.

Recent Findings: Based on findings from recent studies of EHS, the prevalence is higher than previously suggested by the literature, which historically has consisted mostly of case reports. The typical presentation also has been better illustrated by recent case series, and diagnostic criteria have been defined. Read More

Rev Neurol (Paris) 2018 Sep - Oct;174(7-8):532-539. Epub 2018 Jul 25.

Narcolepsy and Idiopathic Hypersomnia National Reference Centre, 75000 Paris, France; Neurology Department, Sleep disorders Unit, Gui-De-Chauliac Hospital, 34295 Montpellier, France; Inserm U1061, UM1, 34295 Montpellier, France.

Augmentation syndrome is one of the most severe complications of RLS. It is characterised by a worsening of treated symptoms; principally an increase in the severity of symptoms and an earlier onset time. Augmentation syndrome occurs primarily with dopaminergic treatments. Read More