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Sleep Med 2019 Mar 20. Epub 2019 Mar 20.

Dream & Nightmare Laboratory, Center for Advanced Research in Sleep Medicine, CIUSSS-NÎM-Hôpital du Sacré-Coeur de Montréal, Canada. Electronic address:

Objective: Childhood adversity figures prominently in the clinical histories of children and adolescents suffering from a panoply of physical, mental or sleep disorders, including posttraumatic stress disorder. But the nature and prevalence of early adversity in the case of idiopathic nightmare-prone individuals have received little study. We characterize the types and frequencies of self-reported childhood adversity for nightmare-prone individuals using the developmentally sensitive Traumatic Antecedents Questionnaire (TAQ) and assess relationships between separation adversity and sleep spindles. Read More

Acta Med Port 2019 Mar 29;32(3):195-201. Epub 2019 Mar 29.

Unidade de Neurodesenvolvimento. Centro da Criança e do Adolescente. CUF Descobertas Hospital. Lisboa. Portugal.

Introduction: The Portuguese version of the Children's Sleep Habits Questionnaire showed adequate psychometric properties in a community sample but the American cut-off seemed inadequate. This study aimed to validate this questionnaire in clinical populations of children with sleep disorders and with attention deficit/ hyperactivity disorder.

Material And Methods: The study sample included 148 Portuguese children aged 2 to 10 years old that where divided in 3 groups: 1. Read More

Cureus 2019 Jan 8;11(1):e3848. Epub 2019 Jan 8.

Internal Medicine, University of California San Francisco, Fresno, USA.

Insomnia and parasomnias are common patient complaints during hospital stay. New environment, the severity of underlying disease, level of care, medications, and infections are all known factors that contribute toward insomnia. Zolpidem is a common sleep aid used for this purpose. Read More

Cureus 2018 Dec 31;10(12):e3807. Epub 2018 Dec 31.

Pulmonary Medicine, Marshall University School of Medicine, Huntington, USA.

Parasomnias are a group of sleep disorders characterized by abnormal, unpleasant motor verbal or behavioral events that occur during sleep or wake to sleep transitions. Parasomnias can occur during non-rapid eye movement (NREM) and rapid eye movement (REM) stages of sleep and are more commonly seen in children than the adult population. Parasomnias can be distressful for the patient and their bed partners and most of the time, these complaints are brought up by their bed partners because of the possible disruption in their quality of sleep. Read More

BMC Pediatr 2019 Mar 6;19(1):70. Epub 2019 Mar 6.

School of Public Health, The University of Queensland, QLD, Brisbane, 4006, Australia.

Background: The effects of prenatal maternal smoking have been studied extensively, however little research has examined the effects of prenatal exposure to maternal smoking on offspring sleep, particularly over several developmental periods. We examined the effects of prenatal maternal smoking and postnatal smoking from birth to 14 years, on offspring sleep at 6 months, 5, 14 and 21 years.

Methods: This was a prospective, community-based birth cohort study involving 7223 women who delivered a singleton child in Brisbane, Australia between 1981 and 1983. Read More

Int J Psychiatry Med 2019 Mar 1:91217419829988. Epub 2019 Mar 1.

3 Department of Child and Adolescent Psychiatry, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.

Objective: Chronic adenotonsillar hypertrophy is the most common etiologic reason for upper airway obstruction in childhood and has been found to be associated with a variety of psychiatric disorders and poor quality of life. In the present study, we investigated the impact of adenotonsillectomy on attention deficit hyperactivity disorder symptoms, sleep problems, and quality of life in children with chronic adenotonsillar hypertrophy.

Methods: The parents of children with chronic adenotonsillar hypertrophy filled out the Conners's Parent Rating Scale-Revised Short form (CPRS-RS), Children's Sleep Habits Questionnaire (CSHQ), and Pediatric Quality of Life Inventory, Parent version (PedsQL-P) before and six months after adenotonsillectomy. Read More

Brain Behav 2019 Mar 15;9(3):e01230. Epub 2019 Feb 15.

Department of Biomedical and NeuroMotor Sciences (DiBiNeM), University of Bologna, Bologna, Italy.

Objectives: To investigate the prevalence of REM sleep behavior disorder (RBD) in patients with inflammatory arthritis (IA) to ascertain if RBD could be an internal red flag signaling a fluctuating state of inflammation based on the theory of "protoconsciousness".

Materials & Methods: One hundred and three patients with a confirmed diagnosis of IA were consecutively recruited. The patients underwent general (IA activity, functional status, laboratory tests) and neurological evaluations. Read More

J Neurol 2019 Apr 11;266(4):1007-1015. Epub 2019 Feb 11.

Department of Neurology, Washington University School of Medicine, Saint Louis, MO, USA.

Objectives: Autoimmune encephalitis (AE) is increasingly recognized as an important cause of subacute cognitive decline, seizures, and encephalopathy, with an ever-broadening clinical phenotype. Sleep disturbances are reported in AE patients, including rapid eye movement sleep behavior disorder, hypersomnia, fragmented sleep, and sleep-disordered breathing; however, the prevalence of sleep disturbances and contributions to outcomes in AE patients remain unknown. There is a need to determine the prevalence of sleep disturbances in AE patients, and to clarify the relationship between specific autoantibodies and disruptions in sleep. Read More

J Clin Sleep Med 2019 Feb 15;15(2):355-357. Epub 2019 Feb 15.

Cleveland Clinic Sleep Disorders Center, Cleveland, Ohio.

Abstract: The most common sleep disorders that can result in injurious or violent behaviors include REM sleep behavioral disorder, sleepwalking, comorbid parasomnias, sleep-related dissociative disorder, and obstructive sleep apnea. Video polysomnography is usually indicated to evaluate recurring sleep-related injury in adults. Only one-third of patients with complex paroxysmal nocturnal events will have one of their habitual events on a single night of in-laboratory video polysomnography, most often those who have prominent, high-frequency motor features. Read More

J Clin Sleep Med 2019 Feb 15;15(2):253-264. Epub 2019 Feb 15.

Center for Advanced Research in Sleep Medicine, CIUSSS-NÎM - Hôpital du Sacré-Coeur de Montréal, Montréal, Québec, Canada.

Study Objectives: Growing evidence suggests that nightmares have considerable adverse effects on waking behavior, possibly by increasing post-sleep negative emotions. Dysphoric reactions to nightmares are one component of nightmare severity for which the neural correlates are unknown. Here, we investigate possible neural correlates of nightmare severity in a sample of individuals who frequently recall nightmares. Read More

Rev Med Chil 2018 Sep;146(9):1041-1049

Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Concepción, Concepción, Chile.

Restless Legs Syndrome (RLS) or Willis-Ekbom Disease is an under-diagnosed chronic and progressive primary sensory-motor disorder. It can lead to severe sleep disturbances, a usual cause of consultation. It is characterized by an urgent need to move the legs in resting situations, a cardinal symptom that is usually accompanied by an unpleasant sensation in legs. Read More

Clin Neuropharmacol 2019 Mar/Apr;42(2):52-54

Departments of Family Medicine and.

Background: Non-rapid-eye-movement (NREM) parasomnias are disorders of sleep ranging from confusional arousals to sleepwalking and sleep-related eating disorders. Historically, antidepressants and benzodiazepines were recommended in treatment of NREM parasomnias. In this case report, we are reporting the use of buspirone in a patient with NREM parasomnias, which produced substantial resolution of symptoms. Read More

J Sleep Res 2019 Jan 29:e12820. Epub 2019 Jan 29.

Department of Clinical Psychology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

This consensus paper provides an overview of the state of the art in research on the aetiology and treatment of nightmare disorder and outlines further perspectives on these issues. It presents a definition of nightmares and nightmare disorder followed by epidemiological findings, and then explains existing models of nightmare aetiology in traumatized and non-traumatized individuals. Chronic nightmares develop through the interaction of elevated hyperarousal and impaired fear extinction. Read More

Soc Dev 2018 Nov 26;27(4):967-983. Epub 2018 Apr 26.

Arizona State University.

Children's sleep has both environmental and genetic influences, with stressful family environmental factors like household chaos and marital conflict associated with sleep duration and quality (El-Sheikh, Buckhalt, Mize, & Acebo, 2006; Fiese, Winter, Sliwinski, & Anbar, 2007). However, it is less clear whether sibling conflict is related to sleep duration and children's sleep problems (e.g. Read More

Mo Med 2018 Nov-Dec;115(6):527-532

Madihah Hepburn, MD, Pradeep C. Bollu, MD, Pradeep Sahota, MD, MSMA member since 2003, and Brandi French, MD, are in the Department of Neurology, University of Missouri - Columbia.

Cerebrovascular disease encompassing both ischemic and hemorrhagic strokes are among the leading causes of disability and mortality globally. The current evidence strongly suggests that identifying and addressing sleep disorders should be a part of both primary and secondary stroke prevention. Stroke and sleep are 'bedfellows' since sleep disorders, including sleep-disordered breathing, parasomnias, sleep-related movement disorders, insomnia, and hypersomnia are intimately intertwined with co-morbid cardiovascular conditions and increase stroke risk. Read More

BMC Neurol 2019 Jan 11;19(1). Epub 2019 Jan 11.

Department of Neurology, University of Yamanashi, 1110 Shimokatou, Yamanashi, 409-3898, Japan.

Background: Spinocerebellar ataxia type 31 (SCA 31) is a slowly progressive neurodegenerative disorder characterized by pure cerebellar ataxia. Unlike other CAG repeat diseases, sleep-related problems have not been reported in patients with SCA 31 so far.

Case Presentation: A 67-year-old woman was admitted to our hospital with dysarthria and gait disturbance after onset age of 62 years. Read More

Cochrane Database Syst Rev 2019 01 4;1:CD007834. Epub 2019 Jan 4.

Department of Neurology, Emory University School of Medicine, 12 Executive Park Drive NE, Atlanta, USA, 30329.

Background: Restless legs syndrome (RLS) is a common neurologic disorder that is associated with peripheral iron deficiency in a subgroup of patients. It is unclear whether iron therapy is effective treatment for RLS.

Objectives: To evaluate the efficacy and safety of oral or parenteral iron for the treatment of restless legs syndrome (RLS) when compared with placebo or other therapies. Read More

Zhonghua Nei Ke Za Zhi 2019 Jan;58(1):17-26

Stroke-related sleep disorders (SSD) are common symptoms after stroke, which are common but easily ignored. Studies have shown that sleep disorders in stroke patients would have negative impact on prognosis. However, there is still a lack of consensus and guidance on SSD evaluation and management worldwide. Read More

Schizophr Res 2018 Dec 14. Epub 2018 Dec 14.

Department of Child and Adolescent Psychiatry, Erasmus University Medical Centre-Sophia Children's Hospital, Rotterdam, the Netherlands; Department of Social and Behavioral Science, Harvard TH Chan School of Public Health, Boston, USA. Electronic address:

Background: Psychotic experiences comprise auditory and visual perceptive phenomena, such as hearing or seeing things that are not there, in the absence of a psychotic disorder. Psychotic experiences commonly occur in the general pediatric population. Although the majority of psychotic experiences are transient, they are predictive of future psychotic and non-psychotic disorders. Read More

Pediatr Ann 2018 Dec;47(12):e504-e506

Restless legs syndrome (RLS) is a common pediatric condition that often goes undiagnosed. The genetics and pathophysiology of this sensorimotor condition are still not well understood. RLS can affect any part of the body, but the thighs and calves are the most commonly affected. Read More

Chin Med J (Engl) 2018 Dec;131(24):2976-2985

National Parkinson Foundation Centre of Excellence and The Maurice Wohl Clinical Neuroscience Institute, King's College London and King's College Hospital, London WC2R 2LS, UK.

Praxis (Bern 1994) 2018 Nov;107(24):1319-1323

1 Institut für Rechtsmedizin der Universität Zürich (IRM UZH).

Daytime Sleepiness in Patients with Restless Legs Syndrome: A Risk Factor for Traffic Accidents? Abstract. Restless legs syndrome (RLS) is a symptom complex of predominantly leg-focused paraesthesias and the associated increased urge to move. Since evening exacerbations are typical, many patients suffer from sleep disorders, which can lead to increased daytime fatigue in the long term. Read More

Tuberk Toraks 2018 Sep;66(3):217-223

Department of Chest Diseases, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.

Introduction: We aimed to investigate the relationship between frequency of restless legs syndrome (RLS), depression, anxiety and sleep quality among medical school students.

Materials And Methods: We applied a questionnaire to medical school students. This questionnaire includes some questions about demographic features of participants, questions related with RLS diagnosis, the pittsburgh sleep quality index (PSQI), beck-depression-scale (BDS), beck-anxiety scale (BAS) to all subjects. Read More

Sleep 2018 Nov 26. Epub 2018 Nov 26.

Minnesota Regional Sleep Disorders Center, Departments of Psychiatry, Hennepin County Medical Center and University of Minnesota Medical School, Minneapolis, MN, USA.

Study Objectives: Complex sexual behavior during sleep (CSBS) is a well described clinical entity in NREM sleep parasomnias (i.e. sexsomnia). Read More

J Back Musculoskelet Rehabil 2019 ;32(1):1-6

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Adiyaman University, Adiyaman, Turkey.

Objectives: To evaluate the efficacy of Kinesio taping (KT) in patients with sleep bruxism (SB) and to determine whether KT may be an alternative for occlusal splint (OS) for the treatment of SB.

Materials And Methods: Sixteen patients with SB were treated with KT (kinesio group) and 18 patients were treated with OS (splint group). Masseter and temporal muscle pressure pain thresholds (MPPT and TPPT), visual analogue scale (VAS) values and mouth opening measurements of patients were compared before treatment, and at the 1st and 5th weeks of treatment. Read More

Cureus 2018 Sep 22;10(9):e3345. Epub 2018 Sep 22.

Neurology, University of Missouri, Columbia, USA.

Sleep disorders constitute a major aspect of the non-motor symptoms of Parkinson's disease (PD). Rapid eye movement (REM) behavior disorders are the most frequently experienced parasomnias in patients with PD. Non-REM sleep disorders like confusional arousals, sleep terrors, sleepwalking, and sleep-related eating disorder (SRED) are also associated with PD. Read More

Curr Biol 2018 Nov 19;28(22):R1288-R1289. Epub 2018 Nov 19.

Institut du Cerveau et de la Moelle, Sorbonne University, Pitié Salpêtrière Hospital, Paris, France. Electronic address:

Arnulf describes the fascinating behavior of sleepwalking and its associated parasomnias. Read More

Acta Neurol Scand 2019 Mar 3;139(3):260-268. Epub 2018 Dec 3.

Department of Neurology, Dokkyo Medical University, Tochigi, Japan.

Background: The clinical-radiological correlation between restless legs syndrome (RLS) or its variants and acute ischemic stroke remains unclear.

Methods: This study prospectively included 104 consecutive patients with acute ischemic stroke, confirmed by diffusion-weighted imaging. The frequency and clinical characteristics of RLS or RLS variants were evaluated according to the International RLS Study Group criteria, as was the topography of the associated lesions. Read More

Handb Exp Pharmacol 2018 Nov 16. Epub 2018 Nov 16.

Wisconsin Institute for Sleep and Consciousness, University of Wisconsin Madison, Madison, WI, USA.

Sleep and wakefulness are highly complex processes that are elegantly orchestrated by fine-tuned neurochemical changes among neuronal and non-neuronal ensembles, nuclei, and networks of the brain. Important neurotransmitters and neuromodulators regulating the circadian and homeostatic facets of sleep-wake physiology include melatonin, γ-aminobutyric acid, hypocretin, histamine, norepinephrine, serotonin, dopamine, and adenosine. Dysregulation of these neurochemical systems may cause sleep-wake disorders, which are commonly classified into insomnia disorder, parasomnias, circadian rhythm sleep-wake disorders, central disorders of hypersomnolence, sleep-related movement disorders, and sleep-related breathing disorders. Read More

Prague Med Rep 2018;119(2-3):85-96

Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.

Parkinson's disease is a neurodegenerative disorder with the pathological accumulation of alpha synuclein in the brain and peripheral nerve tissue. Early stages of synucleinopathies, often present clinically with rapid eye movement (REM) sleep disorder (RBD). Clinical markers that indicate early progression from RBD to manifest synucleinopathies include abnormal dopamine transporter (DAT) imaging, motor and non-motor symptoms. Read More

Sleep Med 2019 Jan 29;53:28-34. Epub 2018 Sep 29.

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada. Electronic address:

Objectives: To examine associations between parent-reported child sleep walking or talking, nightmares, and trouble sleeping at age eight and psychiatric problems in adulthood (age 30-35) in extremely low birth weight (ELBW; <1000 g) survivors and matched normal birth weight (NBW; >2500 g) control participants.

Methods: At age eight, parents of ELBW survivors and NBW control participants completed sleep items on the Child Behavior Checklist assessing the presence of sleep walking/talking, nightmares, or trouble sleeping. At age 30-35, 98 ELBW and 94 NBW individuals completed the Mini International Neuropsychiatric Interview (MINI), Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI). Read More

Sleep Med Clin 2018 Dec 26;13(4):571-582. Epub 2018 Sep 26.

Center for Advanced Research in Sleep Medicine, Höpital du Sacré-Cœur de Montréal, 5400 Boulevard Gouin Ouest, Montréal, Québec H4J 1C5, Canada.

The aim of this article is to introduce transcranial magnetic stimulation (TMS) to dental practitioners and to explain its use in obstructive sleep apnea (OSA) and sleep bruxism (SB). In these 2 sleep disorders, TMS has proven to be a useful tool to explore pathophysiological pathways and disease mechanisms, and in a more limited way, to recruit upper airway muscles in OSA and reduce muscle activity and pain intensity in SB. Although promising, research using TMS in these conditions is still very limited and future investigations should be conducted before its clinical application can be considered. Read More

Am J Orthod Dentofacial Orthop 2018 Nov;154(5):718-732

Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan. Electronic address:

Prader-Willi syndrome (PWS) is a complex disorder that affects multiple systems and may cause craniofacial and dentofacial abnormalities. However, there is still a lack of evidence in the literature regarding the progress of orthodontic treatment in patients with PWS. This case report describes the successful orthodontic treatment of a patient with PWS. Read More

J Oral Facial Pain Headache 2018 Fall;32(4):375-380

Aims: To investigate whether a dose-response relationship exists between the intensity of pain-related temporomandibular disorders (TMDs) and the amount of self-reported bruxism activities in a group of TMD pain patients.

Methods: A total of 768 patients referred to a specialized clinic for complaints of orofacial pain and dysfunction were initially enrolled in the study. Of these patients, 293 who were diagnosed with at least one type of pain-related TMD according to the Diagnostic Criteria for Temporomandibular Disorders were selected. Read More

Nat Sci Sleep 2018 10;10:317-326. Epub 2018 Oct 10.

"Claudio Munari" Center for Epilepsy Surgery, Niguarda Hospital, Milan, Italy,

Sleep-related hypermotor epilepsy (SHE), previously called nocturnal frontal lobe epilepsy (NFLE), is a focal epilepsy characterized by asymmetric tonic/dystonic posturing and/or complex hyperkinetic seizures occurring mostly during sleep. SHE fulfills the definition of rare disease with an estimated minimum prevalence of 1.8/100,000 individuals, and it represents about 10% of drug-resistant surgical cases. Read More

Oxid Med Cell Longev 2018;2018:7612172. Epub 2018 Sep 18.

Graduation Program in Biochemistry, Federal Pampa University, Uruguaiana, RS, Brazil.

J Vet Intern Med 2018 Nov 12;32(6):2029-2036. Epub 2018 Oct 12.

Neurology Department, Queen Mother Hospital for Animals, Royal Veterinary College, London, United Kingdom.

Background: Abnormal sleep behavior has been reported in 5 dogs during recovery from tetanus.

Hypothesis: REM sleep behavior disorder (RBD) is a more common consequence of tetanus than previously reported in veterinary literature and easily confused for epileptic seizures.

Animals: Sixty-one client-owned dogs diagnosed with tetanus at 2 UK referral centers. Read More

J Clin Neurosci 2019 Jan 9;59:254-258. Epub 2018 Oct 9.

Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address:

The current study aimed to investigate the occurrence and clinical associations of rapid eye movement (REM) behavior disorder (RBD) in early-stage Parkinson's disease (PD) from a cohort of Chinese patients. 158 treatment-naive PD patients in total were enrolled in the study. Each patient was categorized as PD with or without RBD according to the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire (RBDSQ). Read More

Int Rev Neurobiol 2018 24;141:439-467. Epub 2018 Aug 24.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Vita-Salute San Raffaele University, Milan, Italy.

Functional MRI (fMRI) has been widely used to study abnormal patterns of brain connectivity at rest and activation during a variety of tasks in patients with idiopathic Parkinson's disease (PD). fMRI studies in PD have led to a better understanding of many aspects of the disease including both motor and non-motor symptoms. Although its translation into clinical practice is still at an early stage, fMRI measures hold promise for multiple clinical applications in PD, including the early detection, predicting future change in clinical status, and as a marker of alterations in brain physiology related to neurotherapeutic agents and neurorehabilitative strategies. Read More

J Clin Neurosci 2019 Feb 8;60:93-95. Epub 2018 Oct 8.

Department of Neurology and Movement Disorder Center, Parkinson Study Group and Neuroscience Research Institute, College of Medicine, Seoul National University, Seoul, South Korea. Electronic address:

Some of patients with Parkinson's disease (PD) have abnormal tandem gait (TG) performance without any symptoms and signs of cerebellar dysfunction. Clinical difference between patients with good and poor TG performance has not yet been studied. We report the relationship between tandem gait performance and clinical characteristics including 37 patients with PD who had no evidence of cerebellar dysfunction. Read More

J Sleep Res 2019 Apr 8;28(2):e12772. Epub 2018 Oct 8.

Sleep Disorders Centre, Guy's Hospital, London, UK.

Although video polysomnography (vPSG) is not routinely recommended for the evaluation of typical cases of non-rapid eye movement (NREM) parasomnias, it can aid diagnosis of unusual cases, other sleep disorders and complicated cases with REM behaviour disorder (RBD), and in differentiating parasomnias from epilepsy. In this study, we aimed to assess vPSG findings in consecutive patients with a clinical diagnosis of NREM-parasomnia covering the whole phenotypic spectrum. Five hundred and twelve patients with a final diagnosis of NREM parasomnia who had undergone vPSG were retrospectively identified. Read More

Am J Med 2019 Mar 4;132(3):292-299. Epub 2018 Oct 4.

Department of Neurology, Brigham and Women's Hospital, Boston, Mass.

Sleep disorders are frequent and can have serious consequences on patients' health and quality of life. While some sleep disorders are more challenging to treat, most can be easily managed with adequate interventions. We review the main diagnostic features of 6 major sleep disorders (insomnia, circadian rhythm disorders, sleep-disordered breathing, hypersomnia/narcolepsy, parasomnias, and restless legs syndrome/periodic limb movement disorder) to aid medical practitioners in screening and treating sleep disorders as part of clinical practice. Read More

Psychopharmacology (Berl) 2018 Nov 5;235(11):3083-3091. Epub 2018 Oct 5.

Department of Psychiatry and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.

Sleep paralysis is a state of involuntary immobility occurring at sleep onset or offset, often accompanied by uncanny "ghost-like" hallucinations and extreme fear reactions. I provide here a neuropharmacological account for these hallucinatory experiences by evoking the role of the serotonin 2A receptor (5-HTR). Research has shown that 5-HTR activation can induce visual hallucinations, "mystical" subjective states, and out-of-body experiences (OBEs), and modulate fear circuits. Read More

Neurol Sci 2019 Jan 2;40(1):227-228. Epub 2018 Oct 2.

Neurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milano, Italy.

The recent manuscript by Xinglong Yang and colleagues provided the first relatively reliable estimate of restless leg syndrome (RLS) prevalence among migraine sufferers, which was estimated at 19% (95% CI 14-24%). The implications of the association between the two conditions are wide, and call for further action aimed to address common disease mechanism-associated conditions such as sleep-related ones and associated burden. Read More

Rinsho Shinkeigaku 2018 Oct 29;58(10):617-621. Epub 2018 Sep 29.

Department of Neurology, Dokkyo Medical University.

A 57-year-old woman had been suffered from insomnia due to restlessness and abnormal sensation of the left side of the body for 33 years. Since the preceding year of the first visit frequency of the symptoms increased, and the abnormal sensation was spread to the right leg. Her daughter had restless legs syndrome (RLS) since age 20. Read More

Nihon Eiseigaku Zasshi 2018 ;73(3):365-372

Graduate School of Health and Nursing Science, Wakayama Medical University.

Objectives: In this study, we examined whether a combined regimen of a short-term nap and a light physical exercise is effective in improving sleep among elderly individuals with mild-to-moderate dementia in communal living group homes.

Methods: Twenty-three female residents (aged 87.4±5. Read More

Mo Med 2018 Mar-Apr;115(2):169-175

Pradeep C. Bollu, MD, Munish K. Goyal, MD, Mahesh Thakkar, PhD, and Pradeep Sahota, MD, MSMA member since 2003, are in the Department of Neurology, University of Missouri - Columbia.

Parasomnias are abnormal and undesirable behaviors during sleep and are thought to be due to the sleep state instability. Some of them are benign, while some of them point to a possible underlying neurodegenerative process. This article briefly discusses the clinical characteristics, demographics, and pathophysiology of major parasomnias and associated disorders. Read More

Neurophysiol Clin 2018 Oct 15;48(5):277-286. Epub 2018 Sep 15.

NeuroPain Team, Inserm U 1028/CNRS, UMR 5292, University of Lyon, Lyon Neuroscience Research Centre (CRNL), 69677 Bron, France.

Objective: Differential diagnosis between sleep-related epileptic seizures and NREM parasomnia remains challenging. Pathophysiological markers to differentiate both conditions are needed. Activation of autonomic system is present in arousal reactions and epileptic seizures. Read More