7,563 results match your criteria Parasitology[Journal]


First isolation of Leishmania infantum by blood culture in bovines from endemic area for canine visceral leishmaniasis.

Parasitology 2019 Feb 20:1-3. Epub 2019 Feb 20.

Department of Tropical Diseases,Botucatu Medical School, São Paulo State University - UNESP,Botucatu, São Paulo 18618-970,Brazil.

Leishmaniasis is considered a parasitic disease that still causes serious consequences for mankind, because it presents a high mortality rate worldwide. Considered multi-hosts, the parasites of the genus Leishmania are able of infecting a wide variety of animal species. The dog was considered the main source of infection of visceral leishmaniasis (VL), in the urban area. Read More

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http://dx.doi.org/10.1017/S0031182019000088DOI Listing
February 2019

Could angiotensin-modulating drugs be relevant for the treatment of Trypanosoma cruzi infection? A systematic review of preclinical and clinical evidence.

Parasitology 2019 Feb 20:1-14. Epub 2019 Feb 20.

Department of Structural Biology,Institute of Biomedical Sciences, Federal University of Alfenas,Alfenas, 37130-001, Minas Gerais,Brazil.

Although leucocytes are targets of renin-angiotensin system (RAS) effector molecules and RAS-modulating drugs exert immunomodulatory effects, their impact on Trypanosoma cruzi infection remains poorly understood. By using the framework of a systematic review, we integrated the preclinical and clinical evidence to investigate the relevance of angiotensin-inhibiting drugs on T. cruzi infections. Read More

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http://dx.doi.org/10.1017/S003118201900009XDOI Listing
February 2019
1 Read

The relationship between parasite virulence and environmental persistence: a meta-analysis.

Parasitology 2019 Feb 19:1-6. Epub 2019 Feb 19.

Department of Zoology,University of Oxford,Mansfield Road, Oxford, OX1 3SZ,UK.

Why some parasites evolve and maintain extreme levels of virulence is a question that remains largely unanswered. A body of theory predicts that parasites that form long-lived spores able to persist in the environment evolve higher virulence, known as the sit and wait hypothesis. Such parasites can obliterate their local host population and wait in the environment for further hosts to arrive, reducing some of the costs of high virulence. Read More

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http://dx.doi.org/10.1017/S0031182019000015DOI Listing
February 2019

Protein O- and C-Glycosylation pathways in Toxoplasma gondii and Plasmodium falciparum.

Parasitology 2019 Feb 18:1-12. Epub 2019 Feb 18.

Department of Clinical Biochemistry OE4340,Hannover Medical School,Carl-Neuberg-Strasse 1, 30625 Hannover,Germany.

Apicomplexan parasites are amongst the most prevalent and morbidity-causing pathogens worldwide. They are responsible for severe diseases in humans and livestock and are thus of great public health and economic importance. Until the sequencing of apicomplexan genomes at the beginning of this century, the occurrence of N- and O-glycoproteins in these parasites was much debated. Read More

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http://dx.doi.org/10.1017/S0031182019000040DOI Listing
February 2019

Antiprotozoal investigation of 20 plant metabolites on Trypanosoma cruzi and Leishmania amazonensis amastigotes. Atalantoflavone alters the mitochondrial membrane potential.

Parasitology 2019 Feb 13:1-8. Epub 2019 Feb 13.

Department of Pharmaceutical Sciences,Universidade Federal de Santa Catarina,88040-900, Florianópolis, SC,Brazil.

The study aims to evaluate the antiprotozoal activities of 20 plant metabolites on Trypanosoma cruzi and Leishmania amazonensis amastigotes. Compounds 1-20 were obtained and identified by using chromatographic and spectroscopic techniques. The antiparasitic assays were performed on the intracellular form of T. Read More

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http://dx.doi.org/10.1017/S0031182019000052DOI Listing
February 2019

Re-Emerging foci of visceral leishmaniasis in Armenia - first molecular diagnosis of clinical samples.

Parasitology 2019 Feb 13:1-8. Epub 2019 Feb 13.

Division Molecular Biotechnology and Functional Genomics,Technical University of Applied Sciences Wildau,Hochschulring 1, 15745 Wildau,Germany.

Visceral leishmaniasis (VL) was firstly reported in Armenia in 1913. Following a considerable increase of the number of cases until the mid 1950s, the disease disappeared after 1969 and re-emerged in 1999. Scientific literature about VL in Armenia is available only in Russian or Armenian. Read More

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http://dx.doi.org/10.1017/S0031182019000064DOI Listing
February 2019

Pinning down the role of common luminal intestinal parasitic protists in human health and disease - status and challenges.

Parasitology 2019 Feb 8:1-7. Epub 2019 Feb 8.

Laboratory of Parasitology, Department of Bacteria,Parasites and Fungi, Statens Serum Institut,Artillerivej 5, DK-2300 Copenhagen S,Denmark.

While some single-celled intestinal parasites are direct causes of diarrhoea and other types of intestinal pathology, the impact of other gut micro-eukaryotes on human health remains elusive. The fact that some common luminal intestinal parasitic protists (CLIPPs) have lately been found more often in healthy than in diseased individuals has fuelled the hypothesis that some parasites might in fact be protective against disease. To this end, the use of new DNA technologies has helped us investigate trans-kingdom relationships in the gut. Read More

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http://dx.doi.org/10.1017/S0031182019000039DOI Listing
February 2019
1 Read

Parasite diversity associated with African penguins (Spheniscus demersus) and the effect of host and environmental factors.

Parasitology 2019 Feb 6:1-14. Epub 2019 Feb 6.

Department of Conservation Ecology and Entomology,Stellenbosch University,7602 Stellenbosch,South Africa.

The African penguin (Spheniscus demersus) is a critically endangered species endemic to southern Africa. Limited information is available on the parasite diversity associated with the species in natural settings. This study explores the diversity and incidence of parasites associated with African penguins and their nests, and records the effect of host and environmental factors on parasite infestation. Read More

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http://dx.doi.org/10.1017/S0031182018002159DOI Listing
February 2019

Re-evaluation of merogony of a Cystoisospora ohioensis-like coccidian and its distinction from gametogony in the intestine of a naturally infected dog.

Authors:
J P Dubey

Parasitology 2019 Feb 6:1-6. Epub 2019 Feb 6.

United States Department of Agriculture,Agricultural Research Service,Beltsville Agricultural Research Center, Animal Parasitic Diseases Laboratory,Beltsville, Maryland, 20705-2350,USA.

Four species of Cystoisospora, C. canis, C. ohioensis, C. Read More

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http://dx.doi.org/10.1017/S0031182018002202DOI Listing
February 2019

Morphological characterization and molecular phylogeny of zoonotic trematodes in the freshwater snail Asolene platae.

Parasitology 2019 Feb 6:1-10. Epub 2019 Feb 6.

Universidad Nacional de Cuyo, Facultad de Ciencias Médicas, Instituto de Fisiología,5500 Mendoza,Argentina.

In the context of a broader program dealing with the symbiotic associations of apple snails, we sampled three species that coexist in Lake Regatas (Palermo, Buenos Aires, Argentina). The population of Asolene platae, (but not those of Pomacea canaliculata and Pomacea scalaris) showed trematode larvae (echinocercariae and xiphidiocercariae) in haemocoelic spaces and connective tissue of the digestive gland. The echinocercariae resembled those of the genus Echinochasmus, but lacked sensory hairs on their body and tail; whereas xiphidiocercariae were similar to the xiphidiocercariae armatae belonging to the Opisthoglyphe type. Read More

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http://dx.doi.org/10.1017/S0031182019000027DOI Listing
February 2019
2.560 Impact Factor

Estimating effective population size for a cestode parasite infecting three-spined sticklebacks.

Parasitology 2019 Feb 5:1-14. Epub 2019 Feb 5.

Department of Ecology and Evolutionary Biology,Tulane University,6823 St. Charles Avenue, Lindy Boggs Building, Room 400, New Orleans, LA 70118,USA.

Remarkably few attempts have been made to estimate contemporary effective population size (Ne) for parasitic species, despite the valuable perspectives it can offer on the tempo and pace of parasite evolution as well as coevolutionary dynamics of host-parasite interactions. In this study, we utilized multi-locus microsatellite data to derive single-sample and temporal estimates of contemporary Ne for a cestode parasite (Schistocephalus solidus) as well as three-spined stickleback hosts (Gasterosteus aculeatus) in lakes across Alaska. Consistent with prior studies, both approaches recovered small and highly variable estimates of parasite and host Ne. Read More

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http://dx.doi.org/10.1017/S0031182018002226DOI Listing
February 2019
2 Reads

Development and evaluation of molecular tools for detecting and differentiating intestinal amoebae in healthy individuals.

Parasitology 2019 Jan 14:1-7. Epub 2019 Jan 14.

Laboratoire de recherche 'Parasitologie Médicale, Biotechnologies et Biomolécules', LR 16-IPT-06,Université Tunis El-Manar, Institut Pasteur de Tunis, 13 place Pasteur,B.P. 74 1002 Tunis Belvédère,Tunisia.

Amoebae are single-celled parasites frequently colonizing human gut. However, few molecular tools are available for accurate identification. Here, we evaluated a panel of polymerase chain reactions (PCRs) targeting Entamoeba histolytica, Entamoeba dispar, Entamoeba coli, Entamoeba hartmanni, Entamoeba polecki, Endolimax nana and Iodamoeba bütschlii. Read More

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http://dx.doi.org/10.1017/S0031182018002196DOI Listing
January 2019
1 Read

Malaria infection status of European Robins seems to associate with timing of autumn migration but not with actual condition.

Parasitology 2019 Jan 14:1-7. Epub 2019 Jan 14.

Behavioural Ecology Group,Department of Systematic Zoology and Ecology,Eötvös Loránd University, H-1117 Budapest,Hungary.

Avian malaria parasites can negatively affect many aspects of the life of the passerines. Though these parasites may strongly affect the health and thus migration patterns of the birds also during autumn, previous studies on avian malaria focused mainly on the spring migration and the breeding periods of the birds. We investigated whether the prevalence of blood parasites varies in relation to biometrical traits, body condition and arrival time in the European Robin (Erithacus rubecula) during autumn migration. Read More

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http://dx.doi.org/10.1017/S0031182018002184DOI Listing
January 2019

Survival and energy use of Ixodes scapularis nymphs throughout their overwintering period.

Parasitology 2019 Jan 14:1-10. Epub 2019 Jan 14.

Department of Natural Resources,Cornell University,310 Fernow Hall, Ithaca NY 14853,USA.

The blacklegged tick (Ixodes scapularis) spends up to 10 months in the soil between feeding as larvae and questing for hosts as nymphs the following year. We tracked the survival and energy use of 4320 engorged larvae evenly divided across 288 microcosms under field conditions from September to July on sites with high (>12 nymphs/150 m2) and low (<1.2 nymphs/150 m2) densities of naturally questing I. Read More

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http://dx.doi.org/10.1017/S0031182018002147DOI Listing
January 2019

Molecular data show Clinostomoides Dollfus, 1950 is a junior synonym of Clinostomum Leidy, 1856, with redescription of metacercariae of Clinostomum brieni n. comb.

Parasitology 2019 Jan 14:1-9. Epub 2019 Jan 14.

Department of Veterinary Medical Sciences,Alma Mater Studiorum University of Bologna,Via Tolara di Sopra 50, 40064 Ozzano Emilia (BO),Italy.

The genus Clinostomoides Dollfus, 1950 was erected to accommodate a single worm from Ardea goliath sampled in the Belgian Congo. The specimen was distinguished from other clinostomids by its large size and posterior genitalia. In the following years, metacercariae of Clinostomoides brieni, have been described in Clarias spp. Read More

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http://dx.doi.org/10.1017/S0031182018002172DOI Listing
January 2019
1 Read

In vitro screening of 51 birdsfoot trefoil (Lotus corniculatus L.; Fabaceae) strains for anti-parasitic effects against Haemonchus contortus.

Parasitology 2019 Jan 14:1-9. Epub 2019 Jan 14.

Department of Fisheries, Animal, and Veterinary Sciences,University of Rhode Island,120 Flagg Road, CBLS Rm 177, Kingston, RI 02881,USA.

Secondary plant compounds have shown bioactivity against multi-drug resistant Haemonchus contortus in small ruminants. This study screened 51 strains of birdsfoot trefoil (BFT, Lotus corniculatus) crude aqueous extracts (BFT-AqE) for anti-parasitic activity in vitro against egg hatching, and of those 51 strains, 13 were selected for further testing of motility of first (L1) and third stage (L3) larvae, and exsheathment of L3. Proanthocyanidin content ranged between 1. Read More

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http://dx.doi.org/10.1017/S0031182018002214DOI Listing
January 2019
3 Reads

Trichomonas vaginalis and Mycoplasma hominis: new tales of two old friends.

Parasitology 2019 Jan 8:1-6. Epub 2019 Jan 8.

Department of Biomedical Sciences,University of Sassari,Sassari,Italy.

Trichomonas vaginalis is an anaerobic protist, responsible for the most prevalent non-viral sexually transmitted infection in humans. One of the most intriguing aspects of T. vaginalis pathobiology is the complex relationship with intracellular microbial symbionts: a group of dsRNA viruses belonging to family of Totiviridae (T. Read More

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http://dx.doi.org/10.1017/S0031182018002135DOI Listing
January 2019

Metacyclogenesis of Leishmania (Viannia) guyanensis: a comprehensive study of the main transformation features in axenic culture and purification of metacyclic promastigotes by negative selection with Bauhinia purpurea lectin.

Parasitology 2018 Dec 27:1-12. Epub 2018 Dec 27.

Departamento de Bioquímica e Imunologia,Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais,31.270-901, Belo Horizonte, MG,Brazil.

Leishmania (Viannia) guyanensis is one species that causes cutaneous leishmaniasis in the New World. The incidence of infections with this parasite is probably underestimated and few studies exist on this species, despite its epidemiological importance. In particular, there are no studies concerning L. Read More

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http://dx.doi.org/10.1017/S0031182018002111DOI Listing
December 2018

Avian haemosporidian infections in rufous-collared sparrows in an Andean dry forest: diversity and factors related to prevalence and parasitaemia.

Parasitology 2018 Dec 26:1-9. Epub 2018 Dec 26.

Centro de Investigación de la Biodiversidad y Cambio Climático (BioCamb), Universidad Tecnológica Indoamérica,Machala y Sabanilla, Quito,Ecuador.

Despite intensive research during the last few decades, understanding of ecological and physiological factors related to haemosporidian infections in birds is still fragmentary. Since more model organisms are needed in order to understand these infections in the wild, we analysed avian haemosporidian infections in the rufous-collared sparrow (Zonotrichia capensis, Emberizidae) in a dry forest of the Ecuadorian Andes. Parasite diversity was screened using molecular and morphological approaches. Read More

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http://dx.doi.org/10.1017/S0031182018002081DOI Listing
December 2018

Modelling appropriate use of trypanocides to restrict wide-spread multi-drug resistance during chemotherapy of animal African trypanosomiasis.

Parasitology 2018 Dec 20:1-7. Epub 2018 Dec 20.

Centre for Biotechnology and Bioinformatics, University of Nairobi,P.O. Box 30197, Nairobi,Kenya.

Trypanocide resistance remains a huge challenge in the management of animal African trypanosomiasis. Paucity of data on the prevalence of multi-drug resistant trypanosomes has greatly hindered optimal veterinary management practices. We use mathematical model predictions to highlight appropriate drug regimens that impede trypanocide resistance development in cattle. Read More

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http://dx.doi.org/10.1017/S0031182018002093DOI Listing
December 2018

Prevalence of a nematode castrator of the carrot weevil and impact on fecundity and survival.

Parasitology 2018 Dec 20:1-6. Epub 2018 Dec 20.

Saint-Jean-sur-Richelieu Research and Development Centre, Agriculture and Agri-Food Canada,430 Gouin Boulevard,Saint-Jean-sur-Richelieu (Québec), J3B 3E6,Canada.

Bradynema listronoti is a parasitic nematode described from infected specimens of the carrot weevil Listronotus oregonensis. Prevalence of infection by B. listronoti under field conditions was followed over a period of 16 years in an untreated carrot field. Read More

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http://dx.doi.org/10.1017/S0031182018002056DOI Listing
December 2018

Cellular immunity in the insect Galleria mellonella against insect non-parasitic nematodes.

Parasitology 2018 Dec 20:1-8. Epub 2018 Dec 20.

Department of Applied Biological Sciences,Faculty of Agriculture,Saga University,Saga,Japan.

Immunity to microbial infections is well understood; however, information regarding the immunity to parasitic multicellular organisms remains lacking. To understand innate host cellular immunity to nematodes, we compared the cellular response of the greater wax moth (Galleria mellonella) larvae against the non-parasitic, bacterial-feeding nematode Caenorhabditis elegans and pathogenic nematode Heterorhabditis bacteriophora. When intact first-instar or dauer larvae of C. Read More

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http://dx.doi.org/10.1017/S003118201800210XDOI Listing
December 2018

Neospora caninum cytoplasmic dynein LC8 light chain 2 (NcDYNLL2) is differentially produced by pathogenically distinct isolates and regulates the host immune response.

Parasitology 2018 Dec 18:1-8. Epub 2018 Dec 18.

Animal Parasitic Diseases Laboratory, Agricultural Research Service, USDA,Beltsville, MD 20705,USA.

Neospora caninum is the causative agent of bovine neosporosis. A N. caninum cytoplasmic dynein LC8 light chain (NcDYNLL) protein was characterized in this study. Read More

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http://dx.doi.org/10.1017/S003118201800207XDOI Listing
December 2018
7 Reads

One-year parasitological screening of stray dogs and cats in County Dublin, Ireland.

Parasitology 2018 Dec 18:1-7. Epub 2018 Dec 18.

UCD Veterinary Sciences Centre, University College Dublin,Belfield, Dublin 4,Ireland.

To date, there are no recent studies identifying the prevalence of parasites of human and veterinary importance in dogs and cats in Ireland. The interaction between pets and wildlife species in the environment is an important source of parasite exposure to canids and felines, and one likely to be heightened in the stray animal population. This study aimed to establish the prevalence of endoparasites in unowned dogs and cats in County Dublin, Ireland. Read More

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https://www.cambridge.org/core/product/identifier/S003118201
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http://dx.doi.org/10.1017/S0031182018002020DOI Listing
December 2018
3 Reads

Long live the worms: methods for maintaining and assessing the viability of intestinal stages of Parascaris spp. in vitro.

Parasitology 2018 Dec 18:1-9. Epub 2018 Dec 18.

Department of Veterinary Science,M.H. Gluck Equine Research Center, University of Kentucky,Lexington, KY,USA.

In vitro maintenance of helminth parasites enables a variety of molecular, pharmaceutical and immunological analyses. Currently, the nutritional and environmental in vitro requirements of the equine ascarid parasite, Parascaris spp., have not been determined. Read More

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http://dx.doi.org/10.1017/S0031182018002019DOI Listing
December 2018

Dog hepatocytes are key effector cells in the liver innate immune response to Leishmania infantum.

Parasitology 2018 Dec 18:1-12. Epub 2018 Dec 18.

Global Health and Tropical Medicine, GHTM,Instituto de Higiene e Medicina Tropical, IHMT,Universidade Nova de Lisboa, UNL,Rua da Junqueira 100, 1349-008 Lisboa,Portugal.

Hepatocytes constitute the majority of hepatic cells, and play a key role in controlling systemic innate immunity, via pattern-recognition receptors (PRRs) and by synthesizing complement and acute phase proteins. Leishmania infantum, a protozoan parasite that causes human and canine leishmaniasis, infects liver by establishing inside the Kupffer cells. The current study proposes the elucidation of the immune response generated by dog hepatocytes when exposed to L. Read More

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http://dx.doi.org/10.1017/S0031182018002068DOI Listing
December 2018

Using human head lice to unravel neglect and cause of death.

Parasitology 2018 Dec 10:1-7. Epub 2018 Dec 10.

Ecology and Evolutionary Biology Section, School of Biological Sciences, University of Reading,Reading, RG6 6AS,UK.

Despite the common association of human lice with abandoned or neglected people, no procedure to assess pediculosis, aimed to detect signs of neglect, exists. Investigating the two most common forms of head louse infestation, regular and severe, we define lice-markers of neglect and develop a protocol and survey form to record and assess pediculosis. The study of head lice from a deceased victim of neglect helped unravel time-length since death, frequency of exposure to neglect and the cause and circumstances related to the death. Read More

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http://dx.doi.org/10.1017/S0031182018002007DOI Listing
December 2018
6 Reads

Host species influence on flea (Siphonaptera) infection parameters of terrestrial micromammals in a temperate forest of Mexico.

Parasitology 2018 Nov 29:1-8. Epub 2018 Nov 29.

Centro Tlaxcala de Biología de la Conducta, Universidad Autónoma de Tlaxcala,Km 1.5 Carretera Tlaxcala-Puebla S/N, La Loma Xicohténcatl, C.P. 90070, Tlaxcala, Tlaxcala,México.

Studies of abundance and distribution of organisms are fundamental to ecology. The identity of host species is known to be one of the major factors influencing ectoparasitic flea abundance, but explanations are still needed regarding how host taxa influence abundance parameters of different flea species. This study was carried out at La Malinche National Park (LMNP), Tlaxcala, Mexico, where previously 11 flea species had been recorded on 8 host species. Read More

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http://dx.doi.org/10.1017/S0031182018001981DOI Listing
November 2018

Encephalitozoon cuniculi and Vittaforma corneae (Phylum Microsporidia) inhibit staurosporine-induced apoptosis in human THP-1 macrophages in vitro.

Parasitology 2018 Nov 29:1-11. Epub 2018 Nov 29.

Division of Microbiology,Tulane National Primate Research Center,Covington, LA 70433,USA.

Obligately intracellular microsporidia regulate their host cell life cycles, including apoptosis, but this has not been evaluated in phagocytic host cells such as macrophages that can facilitate infection but also can be activated to kill microsporidia. We examined two biologically dissimilar human-infecting microsporidia species, Encephalitozoon cuniculi and Vittaforma corneae, for their effects on staurosporine-induced apoptosis in the human macrophage-differentiated cell line, THP1. Apoptosis was measured after exposure of THP-1 cells to live and dead mature organisms via direct fluorometric measurement of Caspase 3, colorimetric and fluorometric TUNEL assays, and mRNA gene expression profiles using Apoptosis RT2 Profiler PCR Array. Read More

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http://dx.doi.org/10.1017/S0031182018001968DOI Listing
November 2018

Elucidating in vitro and in vivo phenotypic behaviour of L. infantum/L. major natural hybrids.

Parasitology 2018 Nov 29:1-8. Epub 2018 Nov 29.

Global Health and Tropical Medicine,GHTM, Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL,Rua Junqueira 100, 1349-008 Lisbon,Portugal.

The clinical manifestation and course of Leishmania infections depend on factors such as species, virulence and host-immunity. Although trypanosomatids are considered to have clonal propagation, genetic hybridization has produced successful natural hybrid lineages. Hybrids displaying strong selective advantages may have an impact on pathogenesis and the eco-epidemiology of leishmaniasis. Read More

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http://dx.doi.org/10.1017/S0031182018001993DOI Listing
November 2018
11 Reads

Hepatozoon milleri sp. nov. (Adeleorina: Hepatozoidae) in Akodon montensis (Rodentia: Cricetidae: Sigmodontinae) from southeastern Brazil.

Parasitology 2018 Nov 29:1-8. Epub 2018 Nov 29.

Universidade Estadual Paulista (UNESP), Instituto de Biociências, Departamento de Parasitologia, Campus de Botucatu, Distrito de Rubião Junior,Botucatu, São Paulo,Brazil.

Members of the genus Hepatozoon (Miller, 1908) are blood parasites found in a wide range of host species, including wild rodents; however, information about the life cycle, distribution and Hepatozoon species diversity infecting these mammals are lacking. We studied the parasite stages and DNA sequences of Hepatozoon sp. of 11 naturally infected Akodon montensis. Read More

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http://dx.doi.org/10.1017/S0031182018001956DOI Listing
November 2018

Haematophagic Caenorhabditis elegans - ERRATUM.

Parasitology 2018 Nov 29. Epub 2018 Nov 29.

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http://dx.doi.org/10.1017/S003118201800197XDOI Listing
November 2018

Model systems for investigating disease processes in neurocysticercosis.

Parasitology 2018 Nov 15:1-10. Epub 2018 Nov 15.

Division of Cell Biology, Department of Human Biology,Neuroscience Institute and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town,Anzio Road,Observatory, Cape Town,Western Cape 7935,South Africa.

Neurocysticercosis (NCC) occurs following brain infection by larvae of the cestode Taenia solium. It is the leading cause of preventable epilepsy worldwide and therefore constitutes a critical health challenge with significant global relevance. Despite this, much is still unknown about many key pathogenic aspects of the disease, including how cerebral infection with T. Read More

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http://dx.doi.org/10.1017/S0031182018001932DOI Listing
November 2018
1 Read

Species and site contributions to β-diversity in fleas parasitic on the Palearctic small mammals: ecology, geography and host species composition matter the most.

Parasitology 2018 Nov 15:1-9. Epub 2018 Nov 15.

Wyler Department of Dryland Agriculture,French Associates Institute for Agriculture, French Associates Institute for Agriculture and Biotechnology of Drylands, Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev,Sede Boqer Campus, 84990 Midreshet Ben-Gurion,Israel.

The β-diversity of fleas parasitic on small mammals in 45 regions of the Palearctic was partitioned into species [species contributions to β-diversity (SCBD)] and site ( = assemblage) contributions [local contributions to β-diversity (LCBD)]. We asked what are the factors affecting SCBD and LCBD and tested whether (a) variation in ecological, morphological, life history and geographic traits of fleas can predict SCBD and (b) variation in flea and host community metrics, off-host environmental factors, host species composition of flea assemblages can predict LCBD. We used spatial variables to describe geographic distribution of flea assemblages with various LCBD values. Read More

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http://dx.doi.org/10.1017/S0031182018001944DOI Listing
November 2018
6 Reads

Evaluation of salinomycin isolated from Streptomyces albus JSY-2 against the ciliate, Ichthyophthirius multifiliis.

Parasitology 2018 Nov 14:1-6. Epub 2018 Nov 14.

Agriculture Ministry Key Laboratory of Healthy Freshwater Aquaculture,Key Laboratory of Fish Health and Nutrition of Zhejiang Province,Zhejiang Institute of Freshwater Fisheries,Huzhou,China.

The present study was undertaken to investigate the antiparasitic activity of extracellular products of Streptomyces albus. Bioactivity-guided isolation of chloroform extracts affording a compound showing potent activity. The structure of the compound was elucidated as salinomycin (SAL) by EI-MS, 1H NMR and 13C NMR. Read More

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http://dx.doi.org/10.1017/S0031182018001919DOI Listing
November 2018
1 Read

Trichostatin A induces Trypanosoma cruzi histone and tubulin acetylation: effects on cell division and microtubule cytoskeleton remodelling.

Parasitology 2018 Nov 13:1-10. Epub 2018 Nov 13.

Laboratório de Ultraestrutura Celular Hertha Meyer,Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro-UFRJ,21491-590, Rio de Janeiro, RJ,Brazil.

Trypanosoma cruzi, the causative agent of Chagas disease, is a public health concern in Latin America. Epigenetic events, such as histone acetylation, affect DNA topology, replication and gene expression. Histone deacetylases (HDACs) are involved in chromatin compaction and post-translational modifications of cytoplasmic proteins, such as tubulin. Read More

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http://dx.doi.org/10.1017/S0031182018001828DOI Listing
November 2018

Glucose deprivation activates a cAMP-independent protein kinase from Trypanosoma equiperdum.

Parasitology 2018 Nov 13:1-10. Epub 2018 Nov 13.

Departamento de Biología Celular,Universidad Simón Bolívar,Caracas,Venezuela.

Kemptide (sequence: LRRASLG) is a synthetic peptide holding the consensus recognition site for the catalytic subunit of the cAMP-dependent protein kinase (PKA). cAMP-independent protein kinases that phosphorylate kemptide were stimulated in Trypanosoma equiperdum following glucose deprivation. An enriched kemptide kinase-containing fraction was isolated from glucose-starved parasites using sedimentation throughout a sucrose gradient, followed by sequential chromatography on diethylaminoethyl-Sepharose and Sephacryl S-300. Read More

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http://dx.doi.org/10.1017/S0031182018001920DOI Listing
November 2018
6 Reads

Genetic and morphometric categorization of Taenia ovis from Sheep in Iran.

Parasitology 2018 Nov 13:1-6. Epub 2018 Nov 13.

Research Center for Hydatid Disease in Iran, Kerman University of Medical Sciences,Kerman, 76169-14115,Iran.

Little is known about the genetic and morphological characters of Taenia ovis. The purpose of the present study was to characterize sheep isolates of T. ovis using rostellar hook morphometry as well as mitochondrial genes sequence analysis. Read More

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http://dx.doi.org/10.1017/S0031182018001907DOI Listing
November 2018
8 Reads

Parasite-specific proliferative responses of chicken spleen cells upon in vitro stimulation with Eimeria tenella antigen.

Parasitology 2018 Nov 9:1-9. Epub 2018 Nov 9.

Department of Microbiology,National Veterinary Institute,SE-751 89 Uppsala,Sweden.

This study aimed to set up methodology to monitor parasite-specific T-cell activation in vitro using Eimeria tenella-infected chickens. A sonicated E. tenella sporozoite protein preparation was used for the activation of chicken spleen cell cultures. Read More

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http://dx.doi.org/10.1017/S0031182018001877DOI Listing
November 2018
7 Reads

Insights into the metabolism and behaviour of Varroa destructor mites from analysis of their waste excretions.

Parasitology 2018 Nov 9:1-6. Epub 2018 Nov 9.

Bee Research Laboratory, USDA-ARS Beltsville Agricultural Research Center,Beltsville, Maryland 20705,USA.

Varroa destructor mites (Acari: Varroidae) are harmful ectoparasites of Apis mellifera honey bees. Female foundresses of wax-capped pupal host cells and their daughters feed on host fluids from open wounds on the host's integument. Details of V. Read More

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http://dx.doi.org/10.1017/S0031182018001762DOI Listing
November 2018
3 Reads

Angiostrongylosis in Cerdocyon thous (crab-eating fox) and Lycalopex gymnocercus (Pampas fox) in Southern Brazil.

Parasitology 2018 Nov 5:1-8. Epub 2018 Nov 5.

Department of Clinical Veterinary Pathology,Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul (UFRGS),Av. Bento Gonçalves 9090,42505, Porto Alegre, RS 91540-000,Brazil.

The objective of this study was to identify species of Angiostrongylus spp. infecting wild carnivores in Southern Brazil, as well as to describe gross and histopathological findings associated with the infection. Necropsy was conducted in 16 wild carnivores parasitized by Angiostrongylus spp. Read More

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http://dx.doi.org/10.1017/S0031182018001865DOI Listing
November 2018
9 Reads

Phylogenetic analysis of the superfamily Hemiuroidea (Platyhelminthes, Neodermata: Trematoda) based on partial 28S rDNA sequences.

Parasitology 2018 Nov 5:1-8. Epub 2018 Nov 5.

Russian Federal Research Institute of Fisheries and Oceanography,Moscow, V. Krasnoselskaya Str., 17, 107140,Russia.

In the present paper, the phylogenetic relationships between genera, subfamilies and families of the Hemiuroidea are explored. Twelve new sequences of 28 rDNA and data taken from GenBank (NSBI) on 43 species affiliated to 34 genera were included in the analysis. Most of the hemiuroidean trematodes form two highly supported clades (A and B), which are sister groups to each other. Read More

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http://dx.doi.org/10.1017/S0031182018001841DOI Listing
November 2018
10 Reads

The resistance against Trichinella spiralis infection induced by primary infection with respiratory syncytial virus.

Parasitology 2018 Nov 5:1-9. Epub 2018 Nov 5.

Department of Medical Zoology,Kyung Hee University School of Medicine,Seoul,Korea.

Human infections with Trichinella spiralis and respiratory syncytial virus (RSV) are common, as T. spiralis infections are re-emerging in various parts of the world and RSV infections remain a threat for infants. Yet, studies investigating the relationship pertaining to the two are severely lacking. Read More

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http://dx.doi.org/10.1017/S0031182018001889DOI Listing
November 2018
3 Reads

Substrate specificity of the neutral sphingomyelinase from Trypanosoma brucei.

Parasitology 2018 Nov 5:1-13. Epub 2018 Nov 5.

Biomedical Sciences Research Complex,Schools of Biology and Chemistry,University of St Andrews,Fife, KY16 9ST,UK.

The kinetoplastid parasite Trypanosoma brucei causes African trypanosomiasis in both humans and animals. Infections place a significant health and economic burden on developing nations in sub-Saharan Africa, but few effective anti-parasitic treatments are currently available. Hence, there is an urgent need to identify new leads for drug development. Read More

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http://dx.doi.org/10.1017/S0031182018001853DOI Listing
November 2018
9 Reads

Anthelmintic resistance and novel control options in equine gastrointestinal nematodes.

Parasitology 2018 Nov 5:1-13. Epub 2018 Nov 5.

Faculty of Health and Medical Sciences, Department of Veterinary and Animal Sciences,University of Copenhagen,Frederiksberg,Denmark.

Control of equine nematodes has relied on benzimidazoles (BZs), tetrahydropyrimidines and macrocyclic lactones. The intensive use of anthelmintics has led to the development of anthelmintic resistance (AR) in equine cyathostomins and Parascaris equorum. Field studies indicate that BZ and pyrantel resistance is widespread in cyathostomins and there are also increasing reports of resistance to macrocyclic lactones in cyathostomins and P. Read More

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http://dx.doi.org/10.1017/S0031182018001786DOI Listing
November 2018
4 Reads
2.560 Impact Factor

The leishmanicidal activity of artemisinin is mediated by cleavage of the endoperoxide bridge and mitochondrial dysfunction.

Parasitology 2018 Nov 5:1-10. Epub 2018 Nov 5.

Department of Pharmacology,Institute of Post Graduate Medical Education and Research,Kolkata-700 020,India.

Endoperoxides kill malaria parasites via cleavage of their endoperoxide bridge by haem or iron, leading to generation of cytotoxic oxygen-centred radicals. In view of the Leishmania parasites having a relatively compromised anti-oxidant defense and high iron content, this study aims to establish the underlying mechanism(s) accounting for the apoptotic-like death of Leishmania promastigotes by artemisinin, an endoperoxide. The formation of reactive oxygen species was confirmed by flow cytometry and was accompanied by inhibition of mitochondrial complexes I-III and II-III. Read More

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http://dx.doi.org/10.1017/S003118201800183XDOI Listing
November 2018
8 Reads

Trichodinid infections in internal organs of shorthorn sculpin (Myoxocephalus scorpius) collected around an industrial harbour in Nuuk, Greenland.

Parasitology 2018 Oct 25:1-5. Epub 2018 Oct 25.

Institute for Marine and Antarctic Studies, University of Tasmania,Launceston, Tasmania, 7250,Australia.

Trichodinids are parasites generally found on gills and skin of a broad number of aquatic animals. Only a small number of endozoic species has been reported from the urinary tract, intestine and urogenital system in some fish, amphibians and molluscs. This is the first report on the presence of endozoic trichodinids in the spleen, kidney and liver of shorthorn sculpin (Myoxocephalus scorpius). Read More

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http://dx.doi.org/10.1017/S0031182018001774DOI Listing
October 2018
11 Reads

Effects of temperature on Paramoeba perurans growth in culture and the associated microbial community.

Parasitology 2018 Oct 25:1-10. Epub 2018 Oct 25.

Marine Scotland Science Marine Laboratory,375 Victoria Rd, Aberdeen AB11 9DB,UK.

Population growth, in vitro, of three Paramoeba perurans cultures, one polyclonal (G) and two clonal (B8, CE6, derived from G), previously shown to differ in virulence (B8 > G > CE6), was compared at 10 and 15 °C. B8 showed a significantly higher increase in attached and in suspended amoebae over time at 15 and 10 °C, respectively. CE6 and G also had significantly higher numbers of suspended amoebae at 10 °C compared with 15 °C at experiment termination. Read More

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http://dx.doi.org/10.1017/S0031182018001798DOI Listing
October 2018
4 Reads

Haematophagic Caenorhabditis elegans.

Parasitology 2018 Oct 25:1-7. Epub 2018 Oct 25.

School of Pharmacy, University of Nottingham,Boots Sciences Building,University Park,Nottingham, NG7 2RD,UK.

Caenorhabditis elegans is a free-living nematode that resides in soil and typically feeds on bacteria. We postulate that haematophagic C. elegans could provide a model to evaluate vaccine responses to intestinal proteins from hematophagous nematode parasites, such as Necator americanus. Read More

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https://www.cambridge.org/core/product/identifier/S003118201
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http://dx.doi.org/10.1017/S0031182018001518DOI Listing
October 2018
20 Reads