242,022 results match your criteria Parasites & Vectors [Journal]


Molecular phylogenetics supports a clade of red algal parasites retaining native plastids: taxonomy and terminology revised.

J Phycol 2018 Dec 9. Epub 2018 Dec 9.

Department of Biological Sciences, University of Rhode Island, Kingston, Rhode Island, 02879, USA.

Parasitism is a life strategy that has repeatedly evolved within the Florideophyceae. Historically, the terms adelphoparasite and alloparasite have been used to distinguish parasites based on the relative phylogenetic relationship of host and parasite. However, analyses using molecular phylogenetics indicate that nearly all red algal parasites infect within their taxonomic family, and a range of relationships exist between host and parasite. Read More

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December 2018

Toxoplasma gondii seroprevalence in veterinarians in Finland: Older age, living in the countryside, tasting beef during cooking and not doing small animal practice associated with seropositivity.

Zoonoses Public Health 2018 Dec 9. Epub 2018 Dec 9.

Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.

Practising veterinary medicine has an inherent risk of exposure to zoonotic agents, including the protozoan parasite Toxoplasma gondii. We screened sera of veterinarians authorized to work in Finland for the presence of specific immunoglobulin G antibodies against T. gondii with an enzyme-linked fluorescent assay, and evaluated potential risk factors for T. Read More

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December 2018

A new one-step multiplex PCR assay for simultaneous detection and identification of avian haemosporidian parasites.

Parasitol Res 2018 Dec 7. Epub 2018 Dec 7.

Molecular Ecology and Evolution Laboratory, Department of Biology, Lund University, SE-223 62, Lund, Sweden.

Accurate detection and identification are essential components for epidemiological, ecological, and evolutionary surveys of avian haemosporidian parasites. Microscopy has been used for more than 100 years to detect and identify these parasites; however, this technique requires considerable training and high-level expertise. Several PCR methods with highly sensitive and specific detection capabilities have now been developed in addition to microscopic examination. Read More

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December 2018

Utilizing ticks as forensic indicators in a livestock investigation.

Forensic Sci Med Pathol 2018 Dec 10. Epub 2018 Dec 10.

School of Biological Sciences, Monash University, Scenic Blvd & Wellington Road, Clayton, VIC, 3800, Australia.

Although forensic parasitology remains in its infancy compared with more developed fields like forensic entomology, parasites can be useful forensic indicators. We present the case of an individual who disobeyed animal health legislation and crossed animal quarantine boundaries and two state lines with a cattle tick (Rhipicephalus australis) infested horse. Following recognition of the infestation by animal health officers, the individual asserted that the infestation had occurred either during transport or upon arrival at the site of discovery, and that they had not contravened quarantine legislation. Read More

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December 2018

Metabolic Crosstalk Between Host and Parasitic Pathogens.

Exp Suppl 2018 ;109:421-458

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.

A complex network that embraces parasite-host intrinsic factors and the microenvironment regulated the interaction between a parasite and its host. Nutritional pressures exerted by both elements of this duet thus dictate this host-parasite niche. To survive and proliferate inside a host and a harsh nutritional environment, the parasites modulate different nutrient sensing pathways to subvert host metabolic pathways. Read More

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January 2018

Viral Manipulation of the Host Metabolic Network.

Exp Suppl 2018 ;109:377-401

Centre de Recherche du CHU de Québec, Université Laval, Québec, Canada.

Viruses are intracellular parasites that rely on host machinery to replicate and achieve a successful infection. Viruses have evolved to retain a broad range of strategies to manipulate host cell metabolism and metabolic resources, channeling them toward the production of virion components leading to viral production. Although several viruses share similar strategies for manipulating host cell metabolism, these processes depend on several factors, namely, the viral life cycle and the metabolic and energetic status of the infected cell. Read More

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January 2018

Protozoan Parasite Auxotrophies and Metabolic Dependencies.

Exp Suppl 2018 ;109:351-375

MIVEGEC, IRD, CNRS, University of Montpellier, Montpellier, France.

Diseases caused by protozoan parasites have a major impact on world health. These early branching eukaryotes cause significant morbidity and mortality in humans and livestock. During evolution, protozoan parasites have evolved toward complex life cycles in multiple host organisms with different nutritional resources. Read More

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January 2018

Screening of mosquitoes for filarioid helminths in urban areas in south western Poland-common patterns in European Setaria tundra xenomonitoring studies.

Parasitol Res 2018 Dec 8. Epub 2018 Dec 8.

Department of Influenza Research, National Influenza Center, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791, Warszawa, Poland.

In recent years, numerous studies screening mosquitoes for filarioid helminths (xenomonitoring) have been performed in Europe. The entomological monitoring of filarial nematode infections in mosquitoes by molecular xenomonitoring might serve as the measure of the rate at which humans and animals expose mosquitoes to microfilariae and the rate at which animals and humans are exposed to the bites of the infected mosquitoes. We hypothesized that combining the data obtained from molecular xenomonitoring and phenological studies of mosquitoes in the urban environment would provide insights into the transmission risk of filarial diseases. Read More

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December 2018

Upregulated IGF‑1 in the lungs of asthmatic mice originates from alveolar macrophages.

Mol Med Rep 2018 Dec 5. Epub 2018 Dec 5.

Department of Immunology, Anhui Provincial Key Laboratory of Infection and Immunity, Bengbu Medical College, Bengbu, Anhui 233030, P.R. China.

Asthma is characterized by inflammation and remodeling of the airways. Insulin‑like growth factor-1 (IGF‑1) serves an important role in the repair of lung tissue injury and airway remodeling by elevating collagen and elastin content, increasing the thickness of smooth muscle and promoting the proliferation of lung epithelial and interstitial cells, as well as fibroblasts; however, the content of IGF‑1 and its cellular origin in the lungs of patients with asthma remain unknown. In the present study, a mouse model of asthma was constructed. Read More

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December 2018

pyseer: a comprehensive tool for microbial pangenome-wide association studies.

Bioinformatics 2018 Dec;34(24):4310-4312

Department of Parasites and Microbes, Wellcome Sanger Institute, Hinxton, UK.

Summary: Genome-wide association studies (GWAS) in microbes have different challenges to GWAS in eukaryotes. These have been addressed by a number of different methods. pyseer brings these techniques together in one package tailored to microbial GWAS, allows greater flexibility of the input data used, and adds new methods to interpret the association results. Read More

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December 2018

In Silico and Experimental Evaluation of Primer Sets for Species-Level Resolution of the Vaginal Microbiota Using 16S Ribosomal RNA Gene Sequencing.

J Infect Dis 2018 Aug 23. Epub 2018 Aug 23.

Division of Infectious Diseases, University of Alabama at Birmingham.

Background: Identification of bacteria in human vaginal specimens is commonly performed using 16S ribosomal RNA (rRNA) gene sequences. However, studies utilize different 16S primer sets, sequence databases, and parameters for sample and database clustering. Our goal was to assess the ability of these methods to detect common species of vaginal bacteria. Read More

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Diagnostic accuracy of the 1,3-β-D-glucan test for pneumocystis pneumonia in a tertiary university hospital in Denmark: A retrospective study.

Med Mycol 2018 Dec 11. Epub 2018 Dec 11.

Department of Clinical Microbiology, Copenhagen University Hospital Rigshospitalet, Denmark.

1,3-β-D-glucan (BG), a cell-wall component of most fungi including Pneumocystis (PC), is recommended by international guidelines for screening for pneumocystis pneumonia (PCP) in hematologic patients. We retrospectively validated the BG test in our tertiary university hospital. Forty-five patients (median age 53 years, 33% female) tested for PC by polymerase chain reaction (PCR) and/or immunoflourescence (IF)-microscopy with a stored blood sample within ±5 days of the PC test were tested by the Fungitell (cutoff <60 and >80 pg/ml). Read More

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December 2018

Novel pfkelch13 gene polymorphism associates with artemisinin resistance in eastern India.

Clin Infect Dis 2018 Dec 9. Epub 2018 Dec 9.

Immunology and Microbiology Laboratory, Department of Human Physiology with Community Health, Vidyasagar University, West Bengal, India.

Background: Artesunate-sulfadoxine-pyrimethamine (ASSP) is the frontline artemisinin ombination therapy (ACT) in India. Random, irrational, sub-therapeutic artemisinin doses and self-medication with ACT along with predominance of sulfadoxine-pyrimethamine resistance parasite invoked a strong possibility of emerging artemisinin-resistant malaria parasites.

Methods: This study involved 226 patients with uncomplicated P. Read More

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December 2018

Cross-Species Immune Recognition Between Plasmodium vivax Duffy Binding Protein Antibodies and the Plasmodium falciparum Surface Antigen VAR2CSA.

J Infect Dis 2019 Jan;219(1):110-120

School of Public Health, University of Alberta, Edmonton, Canada.

Background: In pregnancy, Plasmodium falciparum parasites express the surface antigen VAR2CSA, which mediates adherence of red blood cells to chondroitin sulfate A (CSA) in the placenta. VAR2CSA antibodies are generally acquired during infection in pregnancy and are associated with protection from placental malaria. We observed previously that men and children in Colombia also had antibodies to VAR2CSA, but the origin of these antibodies was unknown. Read More

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January 2019

The sickle cell trait affects contact dynamics and endothelial cell activation in -infected erythrocytes.

Commun Biol 2018 30;1:211. Epub 2018 Nov 30.

1Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.

Sickle cell trait, a common hereditary blood disorder, protects carriers from severe disease in infections with the human malaria parasite . Protection is associated with a reduced capacity of parasitized erythrocytes to cytoadhere to the microvascular endothelium and cause vaso-occlusive events. However, the underpinning cellular and biomechanical processes are only partly understood and the impact on endothelial cell activation is unclear. Read More

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November 2018

TOAST Subtypes of Ischemic Stroke and Its Risk Factors: A Hospital-Based Study at Cipto Mangunkusumo Hospital, Indonesia.

Stroke Res Treat 2018 11;2018:9589831. Epub 2018 Nov 11.

Division of Neurovascular-Neurosonology-Neurointervention, Department of Neurology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.

Background And Purpose: Stroke is a leading cause of death and disability, with ischemic stroke as the highest prevalent cases in Indonesia. Ischemic stroke can be classified further into five subtypes according to TOAST classification. Numerous studies have revealed that stroke risk factor has variable correlation with different stroke subtype. Read More

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November 2018

Dissecting the Genomic Architecture of Resistance to Parasitism in the Chicken.

Front Genet 2018 26;9:528. Epub 2018 Nov 26.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Edinburgh, United Kingdom.

Coccidiosis in poultry, caused by protozoan parasites of the genus , is an intestinal disease with substantial economic impact. With the use of anticoccidial drugs under public and political pressure, and the comparatively higher cost of live-attenuated vaccines, an attractive complementary strategy for control is to breed chickens with increased resistance to parasitism. Prior infection with leads to complete immunity against challenge with homologous strains, but only partial resistance to challenge with antigenically diverse heterologous strains. Read More

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November 2018

Nematodes and Microorganisms Interactively Stimulate Soil Organic Carbon Turnover in the Macroaggregates.

Front Microbiol 2018 26;9:2803. Epub 2018 Nov 26.

State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing, China.

The intra-aggregate architecture of soil macroaggregates provides suitable microhabitats for nematodes to graze on microorganisms. However, it is not fully clear how nematodes and microbial communities interactively mediate soil organic carbon (SOC) turnover. Here, we aimed to illustrate the relationships between nematodes, microbial community, and SOC turnover in the macroaggregates of a red soil receiving long-term manure application. Read More

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November 2018

First Complete Genome Sequence of a Hare Calicivirus Strain Isolated from .

Microbiol Resour Announc 2018 Dec 6;7(22). Epub 2018 Dec 6.

Avian and Rabbit Virology Immunology Parasitology Unit, Ploufragan-Plouzané-Niort Laboratory, French Agency for Food, Environmental and Occupational Health & Safety (Anses), Ploufragan, France.

The first full-genome sequence of a hare calicivirus (HaCV), recently characterized as a novel member of the , is described. This presumed nonpathogenic lagovirus is 7,433 nucleotides long, shows the same genomic organization as that of other lagoviruses, and has the highest nucleotide identity (79%) with pathogenic European brown hare syndrome viruses. Read More

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December 2018

Complete Genome Sequence of a Vancomycin-Resistant Sequence Type 203 Enterococcus faecium Strain with Belonging to Complex Type 859.

Microbiol Resour Announc 2018 Jul 19;7(2). Epub 2018 Jul 19.

Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.

In 2014, the first vancomycin-resistant (encoded by ) Enterococcus faecium isolate belonging to sequence type 203 (ST203) and complex type 859 (CT859) was detected in Denmark. In 2016, 64% of the Danish clinical E. faecium isolates belonged to ST203 and CT859. Read More

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Draft Genome Assembly of the Poultry Red Mite, .

Microbiol Resour Announc 2018 Nov 8;7(18). Epub 2018 Nov 8.

Moredun Research Institute (MRI), Edinburgh, United Kingdom.

The poultry red mite, , is a major worldwide concern in the egg-laying industry. Here, we report the first draft genome assembly and gene prediction of , based on combined PacBio and MinION long-read sequencing. The ∼959-Mb genome is predicted to encode 14,608 protein-coding genes. Read More

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November 2018

Draft Genome Sequences of New Isolates and the Known Species of the Family Microbacteriaceae Associated with Plants.

Microbiol Resour Announc 2018 Sep 20;7(11). Epub 2018 Sep 20.

All-Russian Collection of Microorganisms (VKM), G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Pushchino, Russia.

Draft genome sequences of 11 bacteria belonging to the family Microbacteriaceae were obtained using Illumina technology. The genomes of these strains have sizes from 3.14 to 4. Read More

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September 2018

The canary (Passeriformes: Fringillidae) as a new host for in Mexico.

Int J Parasitol Parasites Wildl 2018 Dec 22;7(3):445-449. Epub 2018 Nov 22.

Centro de Investigación y Estudios Avanzados en Salud Animal, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca, Mexico.

(Cringoli and Quesada 1991) (Protozoa, Apicomplexa, Eimeriidae) is reported and described from captive canaries forma (Linnaeus 1758) in Mexico. The oöcysts are subspherical, 25.5 × 23. Read More

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December 2018

A comparison of helminth infections as assessed through coprological analysis and adult worm burdens in a wild host.

Int J Parasitol Parasites Wildl 2018 Dec 14;7(3):439-444. Epub 2018 Nov 14.

Department of Zoology, School of Natural Sciences, Trinity College Dublin, Ireland.

Coprological analysis is the most widely used diagnostic tool for helminth infection in both domestic and wild mammals. Evaluation of the efficacy of this technique is rare, due to the lack of availability of adult worm burden. Where information is available the majority of studies are in small ruminants and seldom in a wild host. Read More

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December 2018

Malaria and Malnutrition: Kwashiorkor Associated with Low Levels of Parasitaemia.

Malar Res Treat 2018 27;2018:7153173. Epub 2018 Sep 27.

Department of Community Medicine and Global Health, Institute of Health and Society, University of Oslo, Oslo, Norway.

Background: The relationship between protein energy malnutrition (PEM) and malaria is controversial. While most studies demonstrate that PEM is associated with greater malaria morbidity, some indicate that PEM may in fact have a protective effect. PEM is differentiated into three subgroups: kwashiorkor (marked protein deficiency), marasmus (calorie deficiency), and kwashiorkor/marasmus. Read More

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September 2018

Prevalence of vancomycin resistance among isolates of enterococci in Iran: a systematic review and meta-analysis.

Adolesc Health Med Ther 2018 15;9:177-188. Epub 2018 Nov 15.

School of Medicine, Ilam University of Medical Sciences, Ilam, Iran,

Introduction: is responsible for 10% of hospital-acquired infections. The purpose of this review was to evaluate the prevalence of vancomycin-resistant (VRE) isolates in Iran using a meta-analysis method.

Materials And Methods: Iranian databases, including Magiran and IranDoc, and international databases, including PubMed and MedLib, were examined carefully, and a total of 20 articles published between 2000 and 2011 were extracted. Read More

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November 2018

An analysis of common foodborne parasitic zoonoses in slaughtered sheep and cattle in Tehran, Iran, during 2015-2018.

Vet World 2018 Nov 24;11(10):1486-1490. Epub 2018 Oct 24.

Department of Food Safety and Hygiene, School of Public Health, Zanjan University of Medical Sciences, Zanjan, Iran.

Background And Aim: Cystic echinococcosis, , and liver flukes, such as spp. and , are important parasitic zoonoses, where they able to cause significant veterinary, medical, and economic problems. The present study was carried out to obtain the updated knowledge on the frequency of hydatidosis, fasciolosis, and dicrocoeliosis in the slaughtered sheep and cattle. Read More

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November 2018

A bibliometric analysis of global research on toxoplasmosis in the Web of Science.

Vet World 2018 Nov 12;11(10):1409-1415. Epub 2018 Oct 12.

Molecular and Cell Biology Research Center, Department of Parasitology, Mazandaran University of Medical Sciences, Sari, Iran.

Aim: This study was designed to evaluate the network productions and research collaborations on toxoplasmosis worldwide.

Materials And Methods: A bibliometric research was carried out using the Web of Science (WOS) database. The analysis unit was the original research articles about toxoplasmosis published between 2000 and 2016 (17 years). Read More

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November 2018

Postmortem detection and histopathological features of canine spirocercosis-induced putative esophageal chondrosarcoma.

Vet World 2018 Nov 3;11(10):1376-1379. Epub 2018 Oct 3.

Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Sri Lanka.

Aim: The objective of this study was to describe and characterize the postmortem and histopathological findings of putative esophageal chondrosarcoma associated with .

Materials And Methods: Spirocerca-associated esophageal nodules were collected from 54 dogs at postmortem examination and were stained with hematoxylin and eosin. Of the cases examined, 15 were selected randomly for further investigation, of which 11 were classified as non-neoplastic nodules while 4 had changes reflecting a neoplastic process. Read More

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November 2018

Prevalence of Epilepsy and its Association with Exposure to : A Community Based, Case-control Study from Rural Northern India.

Ann Indian Acad Neurol 2018 Oct-Dec;21(4):263-269

Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, Punjab, India.

Objectives: Many community-based and hospital-based studies across the world have yielded contradictory results regarding association of positive serology and epilepsy. The present study was planned to analyze disease burden of epilepsy in rural community of North India and its association with exposure to in this part of the world.

Methods: A door-to-door screening survey was carried out in the rural community using a validated questionnaire for epilepsy by trained field workers, which was finally confirmed by trained neurologists. Read More

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December 2018

Neutrophils: New insights and open questions.

Sci Immunol 2018 Dec 7;3(30). Epub 2018 Dec 7.

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.

Neutrophils are the first line of defense against bacteria and fungi and help combat parasites and viruses. They are necessary for mammalian life, and their failure to recover after myeloablation is fatal. Neutrophils are short-lived, effective killing machines. Read More

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December 2018

The direct and indirect inhibition effects of resveratrol against tachyzoites .

Antimicrob Agents Chemother 2018 Dec 10. Epub 2018 Dec 10.

Department of Parasitology, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China

is one of the most widespread obligatory parasitic protozoa which infect nearly all the warm-blooded animals, leading to toxoplasmosis. Current administration of the therapeutic drugs like the combination of pyrimethamine and sulfadiazine shows high rates of toxic side effects and encounters drug resistance in some cases. Resveratrol is a natural plant extracts with multiple functions, such as anti-bacterial, anti-cancer and anti-parasite activities. Read More

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December 2018

Modeling prevention of malaria and selection of drug resistance with different dosing schedules of dihydroartemisinin-piperaquine preventive therapy during pregnancy in Uganda.

Antimicrob Agents Chemother 2018 Dec 10. Epub 2018 Dec 10.

Department of Medicine, University of California, San Francisco, San Francisco, CA, United States

Dihydroartemisinin-piperaquine (DHA-PQ) is under study for intermittent preventive treatment during pregnancy (IPTp), but it may accelerate selection for drug resistance. Understanding the relationships between piperaquine concentration, prevention of parasitemia, and selection for decreased drug sensitivity can inform control policies and optimization of DHA-PQ dosing. Piperaquine concentrations, measures of parasitemia, and genotypes associated with decreased aminoquinoline sensitivity in Africa ( 86Y, 76T) were obtained from pregnant Ugandan women randomized to IPTp with sulfadoxine-pyrimethamine (SP) or DHA-PQ. Read More

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December 2018

Second Hypersensitivity Pneumonitis in the Same Patient Caused by Chinchillas.

J Investig Allergol Clin Immunol 2018 Dec;28(6):441-442

Department of Respiratory Diseases, University Hospital of Besançon, Besançon, France.

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December 2018

Molecular characterisation of immunological memory following homologous or heterologous challenges in the schistosomiasis vector snail, Biomphalaria glabrata.

Dev Comp Immunol 2018 Dec 4. Epub 2018 Dec 4.

Univ. Perpignan Via Domitia, Interactions Hôtes Pathogènes Environments UMR 5244, CNRS, IFREMER, Univ. Montpellier, F-66860, Perpignan, France. Electronic address:

Invertebrate immune response may be primed by a current infection in a sustained manner, leading to the failure of a secondary infection with the same pathogen. The present study focuses on the Schistosomiasis vector snail Biomphalaria glabrata, in which a specific genotype-dependent immunological memory was demonstrated as a shift from a cellular to a humoral immune response. Herein, we investigate the complex molecular bases associated with this genotype-dependant immunological memory response. Read More

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December 2018

Overview of Taenia solium cysticercosis in West Africa.

Acta Trop 2018 Dec 7. Epub 2018 Dec 7.

Bristol Veterinary School, University of Bristol, Langford, Bristol, BS40 5DU, United Kingdom; School of Biological Sciences, Queen's University Belfast, 97, Lisburn Road, Belfast, BT9 7BL, United Kingdom.

Human and porcine cysticercosis is endemic in West Africa, where epilepsy is relatively common, but rarely reported due to fear of stigmatization. Neurocysticercosis, caused by Taenia solium, tends to affect the poor in developing countries and control is hampered by inadequate infrastructure and financial resources coupled with lack of adequate information about its significance and distribution. The risk factors for human cysticercosis are closely associated with the characteristics of smallholder or backyard pig farming systems prevalent in this region. Read More

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December 2018

Wing morphometric analysis of forensically important flesh flies (Diptera: Sarcophagidae) in Thailand.

Acta Trop 2018 Dec 7. Epub 2018 Dec 7.

Department of Parasitology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. Electronic address:

Flesh flies are insects of forensic importance as the larvae associated with human remains can be used to estimate a minimum post-mortem interval (PMI) in most cases. And, because life-history traits can vary across species, correct identification is a mandatory step before being used as evidence. Adult flesh flies are extremely similar in general appearance, which causes difficulty in species identification as it is largely based on the morphology of the male genitalia; this also makes it difficult to identify females. Read More

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December 2018

Molecular diagnosis of toxoplasmosis at the onset of symptomatic primo-infection: a straightforward alternative to serological examinations.

Int J Infect Dis 2018 Dec 4. Epub 2018 Dec 4.

University of Montpellier, Research Unit "MiVEGEC" (CNRS 5290/IRD 224/UM), Montpellier, France; University Hospital Centre of Montpellier, Department of Parasitology-Mycology, Montpellier, France; Molecular Biology 'Pole' of the National Reference Center for Toxoplasmosis, Montpellier, France. Electronic address:

Myopericarditis is a rare but well-documented clinical presentation of primary Toxoplasma gondii infection in immunocompetent patients. Here, early detection of Toxoplasma DNA in the peripheral blood by PCR allowed the diagnosis of acute toxoplasmosis while serological tests were negative. Additional serological evaluations two weeks later confirmed the diagnosis and showed that cardiac manifestations occurred before seroconversion, highlighting the importance of a second serological control in case of suspicion of evolutive infection. Read More

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December 2018
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The antibiotic resistance-free mammalian expression plasmid vector pPAL for development of third generation vaccines.

Plasmid 2018 Dec 6. Epub 2018 Dec 6.

Laboratory of Molecular Parasitology, Department of Cellular and Molecular Biology, Centro de Investigaciones Biológicas (Consejo Superior de Investigaciones Científicas). Calle Ramiro de Maeztu, 9, 28040 Madrid, Spain. Electronic address:

DNA vaccines require a vector to replicate genes and express encoding antigens. Antibiotic resistance genes are often used as selection markers, which must not be released to the environment upon final product commercialization. For this reason, generation of antibiotic resistance-free vectors is imperative. Read More

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December 2018

Strongyloides venezuelensis infection augments arterial blood pressure in male wistar rats.

Acta Trop 2018 Dec 6. Epub 2018 Dec 6.

ICBS- Instituto de Ciências Biológicas e da Saúde, UFMT- Universidade Federal de Mato Grosso, Barra do Garças, Mato Grosso, Brazil. Electronic address:

Strongyloidiasis is an intestinal parasitosis that occurs in humans infected by Strongyloides stercoralis mostly. At its acute phase, symptoms like constipation, diarrhea and abdominal pain can be observed, but become asymptomatic for a long time, until an immunosuppression will start a hyperinfection and the dissemination of the disease, prevalent on the elderly population in tropical countries. Ivermectina treatment is the currently choice for this disease, due to its great efficacy and the results reported. Read More

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December 2018

LPS perception through taste-induced reflex in Drosophila melanogaster.

J Insect Physiol 2018 Dec 7. Epub 2018 Dec 7.

UMR Evolution, Génomes, Comportement, Ecologie, CNRS, IRD, Univ Paris-Sud, Université Paris-Saclay, F-91198 Gif-sur-Yvette, France; AgroParisTech, Université Paris-Saclay, Paris, France. Electronic address:

In flies, grooming serves several purposes, including protection against pathogens and parasites. Previously, we found Escherichia coli or lipopolysaccharides (LPS) can induce grooming behavior via activation of contact chemoreceptors on Drosophila wing. This suggested that specific taste receptors may contribute to this detection. Read More

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December 2018
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Toxicity of phenolic compounds to entomopathogenic nematodes: A case study with Heterorhabditis bacteriophora exposed to lentisk (Pistacia lentiscus) extracts and their chemical components.

J Invertebr Pathol 2018 Dec 4;160:43-53. Epub 2018 Dec 4.

Department of Entomology and Nematology, Agricultural Research Organization, The Volcani Center, Bet Dagan 50250, Israel.

Insects show adaptive plasticity by ingesting plant secondary compounds, such as phenolic compounds, that are noxious to parasites. This work examined whether exposure to phenolic compounds affects the development of insect parasitic nematodes. As a model system for parasitic life cycle, we used Heterorhabditis bacteriophora (Rhabditida; Heterorhabditiade) grown with Photorhabdita luminescens supplemented with different concentrations of plant phenolic extracts (0, 600, 1200, 2400 ppm): a crude ethanol extract of lentisk (Pistacia lentiscus) or lentisk extract fractionated along a scale of hydrophobicity with hexane, chloroform and ethyl acetate; and flavonoids (myricetin, catechin), flavanol-glycoside (rutin) or phenolic acids (chlorogenic and gallic acids). Read More

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December 2018

Besnoitia besnoiti seroprevalence in beef, dairy and bullfighting cattle in Catalonia (north-eastern Spain): A cross-sectional study.

Parasitol Int 2018 Dec 6. Epub 2018 Dec 6.

Institute of Parasitology, Vetsuisse-Faculty, University of Bern, Länggassstrasse 122, CH-3012 Bern, Switzerland; Institute of Parasitology, Vetsuisse-Faculty, University of Zurich, Winterthurerstrasse 266a, CH-3057 Zurich, Switzerland.

Besnoitia besnoiti is the causative agent of bovine besnoitiosis, a chronic and debilitating disease of cattle that recently re-emerged and seems to be spreading in Europe. A cross-sectional serological study was carried out in different cattle herds in Catalonia, north-eastern Spain, to determine the seroprevalence of B. besnoiti in the region. Read More

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December 2018

Transcutaneous immunization using SLA or rLACK skews the immune response towards a Th1 profile but fails to protect BALB/c mice against a Leishmania major challenge.

Vaccine 2018 Dec 5. Epub 2018 Dec 5.

Uniformed Services University of the Health Sciences, Department of Medicine, Bethesda, MD, USA.

Leishmaniasis is an expanding health threat worldwide complicated by the absence of an effective vaccine. We investigated transcutaneous immunization (TCI) as a needle-free immunization route which exploits the abundance of antigen presenting cells in the skin to induce both mucosal and systemic immunity. Leishmania (L. Read More

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December 2018

Phylogenetic position of the parasitic nematode Trophomera (Nematoda, Benthimermithidae): a molecular analysis.

Mol Phylogenet Evol 2018 Dec 7. Epub 2018 Dec 7.

Landcare Research, Private Bag 92170, Auckland Mail Centre, Auckland 1142, New Zealand.

Benthimermithid nematodes are parasites of invertebrates currently classified within their own order. Relationships between the Benthimermithida and other nematode orders, however, remain unclear due to their relatively simple morphology, their rarity, and paucity of molecular sequence data. Here, we combine molecular sequences obtained from Trophomera cf. Read More

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December 2018

Six new dactylogyrid species (Platyhelminthes, Monogenea) from the gills of cichlids (Teleostei, Cichliformes) from the Lower Congo Basin.

Parasite 2018 7;25:64. Epub 2018 Dec 7.

Research Group Zoology: Biodiversity, & Toxicology, Centre for Environmental Sciences, Hasselt University, Agoralaan gebouw D, 3590 Diepenbeek, Belgium - Laboratory of Biodiversity and Evolutionary Genomics, University of Leuven, Charles Deberiotstraat 42, 3000 Leuven, Belgium - Department of Botany and Zoology, Faculty of Science, Masaryk University, Kamenice 735/5, 625 00 Brno, Czech Republic - Zoology Unit, Finnish Museum of Natural History, University of Helsinki, Pohjoinen Rautatiekatu 13, 00100 Helsinki, Finland.

The Lower Congo Basin is characterized by a mangrove-lined estuary at its mouth and, further upstream, by many hydrogeographical barriers such as rapids and narrow gorges. Five localities in the mangroves and four from (upstream) left bank tributaries or pools were sampled. On the gills of Coptodon tholloni, Coptodon rendalli, Hemichromis elongatus, Hemichromis stellifer and Tylochromis praecox, 17 species of parasites (Dactylogyridae & Gyrodactylidae, Monogenea) were found, eight of which are new to science. Read More

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December 2018

Schistosoma haematobium-Schistosoma mansoni Hybrid Parasite in Migrant Boy, France, 2017.

Emerg Infect Dis 2019 Feb 17;25(2). Epub 2019 Feb 17.

Schistosomiasis is frequently detected in persons entering Europe. In 2017, we detected a Schistosoma mansoni-Schistosoma haematobium hybrid parasite infection in a migrant boy from Côte d'Ivoire entering France. Because such parasites might be established in Europe, as illustrated by an outbreak on Corsica Island, vectors of these parasites should be investigated. Read More

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February 2019

Development and Validation of a Copro-Enzyme-Linked Immunosorbent Assay Sandwich for Detection of -Soluble Membrane Antigens in Dogs.

Am J Trop Med Hyg 2018 Dec 10. Epub 2018 Dec 10.

Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú.

Cystic echinococcosis (CE) is a parasitic zoonosis caused by the larval stage of the tapeworm . Detection of the adult stage in the canine definitive host is essential for estimating infection rates, surveillance and monitoring of CE control programs. This study sought to develop and validate a coproantigen sandwich enzyme-linked immunosorbent assay (copro-ELISA), based on antibodies against -soluble membrane antigens (EGMA), that is capable of distinguishing infected and noninfected dogs. Read More

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December 2018

Characteristics of Subpatent Malaria in a Pre-Elimination Setting in Southern Zambia.

Am J Trop Med Hyg 2018 Dec 10. Epub 2018 Dec 10.

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

To achieve and sustain malaria elimination, identification and treatment of the asymptomatic infectious reservoir is critical. Malaria rapid diagnostic tests (RDTs) are frequently used to identify asymptomatic, -infected individuals through test-and-treat strategies, but their sensitivity is low when used in low transmission settings. Characteristics of individuals with subpatent (RDT-negative but polymerase chain reaction [PCR]-positive) parasitemia were evaluated in southern Zambia where malaria transmission has declined and efforts to achieve malaria elimination are underway. Read More

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December 2018

Reemergence of West Nile Virus Infections in Southern Greece, 2017.

Am J Trop Med Hyg 2018 Dec 10. Epub 2018 Dec 10.

Department of Microbiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Greece experienced the largest European West Nile virus (WNV) outbreak in 2010 since the 1996 Romania epidemic. West Nile virus reemerged in southern Greece during 2017, after a 2-year hiatus of recorded human cases, and herein laboratory findings, clinical features, and geographic distribution of WNV cases are presented. Clinical specimens from patients with clinically suspected WNV infection were sent from local hospitals to the Microbiology Department of Medical School, National and Kapodistrian University of Athens, and were tested for the presence of specific anti-WNV antibodies and WNV RNA. Read More

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December 2018