1,240 results match your criteria Parapsoriasis

Healthcare Disparities in the Management of Indolent Mycosis Fungoides.

Cureus 2022 Apr 13;14(4):e24098. Epub 2022 Apr 13.

Dermatology, Elias Emergency University Hospital, Bucharest, ROU.

Mycosis fungoides represents the most common cutaneous T-cell lymphoma, clinically manifested with evolving skin lesions, including patches, plaques, tumors, and erythroderma. Early diagnosis remains difficult to establish because it mimics several benign skin conditions, but maintaining a high index of suspicion for the disease is essential in preventing the progression of a potentially fatal disease. We report the case of a 69-year-old female who presented in our dermatology clinic in 2018 with scaly, indurated, itchy erythematous-violaceus patches and plaques, and tumors disseminated throughout the skin evolving for nine years. Read More

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Parapsoriasis-A Diagnosis with an Identity Crisis: A Narrative Review.

Dermatol Ther (Heidelb) 2022 May 15;12(5):1091-1102. Epub 2022 Apr 15.

Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA, 19104, USA.

Parapsoriasis is an uncommon inflammatory skin disease characterized by chronic patches that may be resistant to therapy. It was primarily introduced and classified 120 years ago, and the original classification incorporated parapsoriasis and pityriasis lichenoides under the umbrella term parapsoriasis. After a major change in classification, parapsoriasis now exclusively refers to small plaque parapsoriasis (SPP) and large plaque parapsoriasis (LPP). Read More

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The first case report of Pityriasis lichenoides chronica following COVID-19 mRNA vaccination.

Dermatol Ther 2022 Jun 21;35(6):e15445. Epub 2022 Mar 21.

Department of Pathology, Faculty of Medicine, Menoufia University, Shibin Al Kawm, Egypt.

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Phototherapy in dermatological maladies (Review).

Exp Ther Med 2022 Apr 3;23(4):259. Epub 2022 Feb 3.

Department of Dermatology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

Since the introduction of modern phototherapy in 1903 by Nobel Prize-winner Niels Ryberg Finsen, the usage of this therapy in the medical field has grown, techniques have been refined and developed, and it has gained widespread acceptance. Psoriasis vulgaris, parapsoriasis, lichen planus, atopic dermatitis, neonatal jaundice, urticaria, morphea, vitiligo, granuloma annulare and cutaneous T cell lymphoma are only a few dermatological indications that come along with satisfactory results. Most often, it is a 2nd or 3rd line therapy being an alternative in more severe or refractory diseases. Read More

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Pityriasis lichenoides et varioliformis acuta after SARS-CoV-2 infection and relapse after vaccination.

J Eur Acad Dermatol Venereol 2022 06 25;36(6):e431-e433. Epub 2022 Feb 25.

Department of Dermatology, Allergology and Venereology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

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Febrile Ulceronecrotic Mucha-Habermann Disease: A Rare Form of Pityriasis Lichenoides et Varioliformis Acuta.

Cutis 2022 Jan;109(1):E8-E11

Dr. Zimmer is from Southeastern Skin Cancer and Dermatology, Huntsville, Alabama. Dr. Clay is from Dermatology Affiliates, Atlanta, Georgia. Dr. Burkemper is from the Department of Dermatology, Saint Louis University School of Medicine, Missouri.

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January 2022

Diagnostic Value of Plasmacytoid Dendritic Cells in Differentiating Pityriasis Lichenoides et Varioliformis Acuta From Lymphomatoid Papulosis.

Am J Dermatopathol 2022 Mar;44(3):174-178

Section of Dermatopathology, Department of Dermatology, Boston University School of Medicine, Boston, MA; and.

Abstract: Pityriasis lichenoides et varioliformis acuta (PLEVA) and lymphomatoid papulosis (LyP) can often demonstrate clinical and histopathologic overlap. A recent study demonstrated significant plasmacytoid dendritic cell (pDC) recruitment in lesions of PLEVA, whereas another study reported minimal pDC recruitment in lesions of LyP. To confirm the possible diagnostic value of pDCs in differentiating PLEVA and LyP, we compared the presence and distribution of pDCs and myxovirus protein A (MxA) expression (an indirect assessment of pDC activity). Read More

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Pityriasis lichenoides et varioliformis acuta following COVID-19 mRNA vaccination.

J Eur Acad Dermatol Venereol 2022 05 25;36(5):e327-e328. Epub 2022 Jan 25.

Departments of Dermatology, Turku University Hospital and University of Turku, Turku, Finland.

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Acute ulceronecrotic rash in a child.

Pediatr Dermatol 2021 Nov;38(6):e55-e57

Department of Dermatology, Farhat Hached Hospital, University of Sousse, Sousse, Tunisia.

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November 2021

The histopathological landscape of the major psoriasiform dermatoses.

Arch Clin Cases 2019 27;6(3):59-68. Epub 2021 Oct 27.

Department of Morphofunctional Sciences I - Histology, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.

Psoriasiform dermatoses represent a wide spectrum of inflammatory conditions, with several major forms represented by psoriasis, as the prototype of this category, followed by pustular psoriasis, Reiter's syndrome, pityriasis rubra pilaris, lichen simplex chronicus and large-plaques parapsoriasis. They create a diagnostic challenge, both clinical and histopathological, because of their complexity and frequent overlapping of the microscopical features. The characteristic histopathological features of psoriasiform reaction comprise extensive hyperkeratosis, with horizontally confluent but vertically intermittent parakeratosis, which alternate with orthokeratosis, thin granular layer, with relative frequent mitoses, uniform elongated and fused rete ridges, edematous superficial papillary dermis, with dilated capillaries, perivascular lymphocytic infiltrate, Munro's microabscesses, and spongiform pustules of Kogoj. Read More

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October 2021

Lymphomatoid drug reaction developed after BNT162b2 (Comirnaty) COVID-19 vaccine manifesting as pityriasis lichenoides et varioliformis acuta-like eruption.

J Eur Acad Dermatol Venereol 2022 Mar 24;36(3):e172-e174. Epub 2021 Nov 24.

Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, "Sapienza" University of Rome, Rome, Italy.

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Hypopigmented lesions in pityriasis lichenoides chronica patients: Are they only post-inflammatory hypopigmentation?

Australas J Dermatol 2022 Feb 9;63(1):68-73. Epub 2021 Nov 9.

Dermatology Department, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt.

Background/objectives: Pityriasis lichenoides chronica (PLC) lesions are reported to subside with post-inflammatory hypopigmentation (PIH); hence, the most widely perceived nature of hypopigmented macules in PLC is PIH. However, to the best of our knowledge, no studies describing histopathological findings in these lesions are reported in literature. The aim of this study is to evaluate the hypopigmented lesions encountered in PLC patients and to shed light on their histopathological features. Read More

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February 2022

Potential role of tumor-associated macrophages and CD163/CD68 ratio in mycosis fungoides and Sézary syndrome in correlation with serum sCD163 and CCL22.

J Cutan Pathol 2022 Mar 14;49(3):261-273. Epub 2021 Nov 14.

Pathology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

Currently, there are no curative treatment options for mycosis fungoides (MF) and Sézary syndrome (SS) other than stem cell transplant. Understanding the interplay between tumor cells and tumor microenvironment could aid in the development of new therapies. Tumor-associated macrophages (TAMs) mostly have M2 phenotype that promotes tumor progression. Read More

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Inpatient care for skin diseases in Germany: multi-source analysis on the current and future health care needs.

J Dtsch Dermatol Ges 2021 10;19 Suppl 5:25-53

Department of Dermatology and Allergology Biederstein, Technical University of Munich (TUM), Munich, Germany.

Background: In Germany, skin diseases are mainly treated in the 115 dermatological hospitals.

Methods: Health care and health economic analysis of dermatological inpatient care and prediction of future care needs based on primary and secondary data.

Results: Outpatient and inpatient care for dermatologic treatment indications is predominantly provided by dermatology specialists. Read More

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October 2021

Next-generation sequencing confirms T-cell clonality in a subset of pediatric pityriasis lichenoides.

J Cutan Pathol 2022 Mar 21;49(3):252-260. Epub 2021 Oct 21.

Department of Dermatology, Stanford University Medical Center, Stanford, California, USA.

Background: Pityriasis lichenoides (PL) is a papulosquamous disease that affects both adults and children. Previous studies have shown a subset of this entity to have clonal T-cell populations via PCR-based assays. In this study, we sought to implement next-generation sequencing (NGS) as a more sensitive and specific test to examine for T-cell clonality within the pediatric population. Read More

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Reasons we should not exclude the term parapsoriasis from the medical vocabulary.

J Cutan Pathol 2021 11 13;48(11):1436-1437. Epub 2021 Oct 13.

Dermatological Outpatient Clinic, Hospital das Clínicas, Medical School of the University of São Paulo, São Paulo, Brazil.

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November 2021

Pityriasis Lichenoides et Varioliformis Acuta Triggered by Human Papillomavirus Vaccine: A Case Report and Literature Review.

Acta Derm Venereol 2021 Sep 17;101(9):adv00552. Epub 2021 Sep 17.

Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, PL-50-368 Wroclaw, Poland.

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September 2021

Reply to "Shall we exclude parapsoriasis from the medical vocabulary?"

Warren R Heymann

J Cutan Pathol 2021 11 26;48(11):1435. Epub 2021 Aug 26.

Division of Dermatology, Cooper Medical School of Rowan University, Camden, New Jersey, USA.

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November 2021

Mucha-Habermann disease: a pediatric case report and proposal of a risk score.

Int J Dermatol 2022 Apr 20;61(4):401-409. Epub 2021 Jul 20.

Department of Paediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare inflammatory dermatological disease. A case of a 13-year-old boy with FUMHD possibly triggered by mycoplasma infection is presented. Based on FUMHD cases identified in a MEDLINE literature search, demographic, treatment, and outcome data were analyzed. Read More

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Clinical aspects and treatment of 56 Chinese patients with Pityriasis lichenoides chronica.

Ital J Dermatol Venerol 2022 Jun 20;157(3):289-290. Epub 2021 Jul 20.

Institute of Dermatology, Guangzhou Medical University, Guangzhou, China -

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Clinical characteristics and long-term outcome of 223 patients with mycosis fungoides at a single tertiary center in Korea: A 29-year review.

J Am Acad Dermatol 2022 06 29;86(6):1275-1284. Epub 2021 Jun 29.

Department of Dermatology, Kosin University College of Medicine, Busan, Korea. Electronic address:

Background: Data regarding Asian patients with mycosis fungoides (MF) are limited.

Objective: We aimed to investigate the clinical profile and long-term outcomes of patients with MF in Korea.

Methods: A retrospective review of 223 patients with MF who were followed up for more than 6 months or died of MF within 6 months of diagnosis was performed. Read More

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Pityriasis lichenoides: a clinical and pathological case series of 49 patients with an emphasis on follow-up.

Clin Exp Dermatol 2021 Dec 27;46(8):1561-1566. Epub 2021 Aug 27.

Department of Dermatology, AP-HP, Hôpital Henri Mondor, Créteil, France.

The classification of pityriasis lichenoides (PL) into pityriasis lichenoides et varioliformis acuta (PLEVA), PL chronica (PLC) and febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is based on both clinical and chronological features. In this retrospective monocentric study, we aimed to investigate the relevance of the classification in routine practice. We enrolled 49 patients (25 female, 24 male; median age 41 years). Read More

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December 2021

From Benign Inflammatory Dermatosis to Cutaneous Lymphoma. DNA Copy Number Imbalances in Mycosis Fungoides versus Large Plaque Parapsoriasis.

Medicina (Kaunas) 2021 May 15;57(5). Epub 2021 May 15.

Research Center for the Morphologic Study of the Skin, Department of Dermatology and Venereology, "Victor Babeș" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timișoara, Romania.

Mycosis fungoides (MF) and large plaque parapsoriasis (LPP) evolution provide intriguing data and are the cause of numerous debates. The diagnosis of MF and LPP is associated with confusion and imprecise definition. Copy number alterations (CNAs) may play an essential role in the genesis of cancer out of genes expression dysregulation. Read More

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[The role Epstein-Barr virus played in the outcome of skin diseases].

J W Lu Y Lu

Zhonghua Yi Xue Za Zhi 2021 Jun;101(20):1458-1462

Department of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.

Since the discovery of Epstein-Barr (EB) virus from the cultured cells in Burkitt lymphoma tissue in African children in 1964, we have gradually taken in its oncogenicity and the link between this virus and multiple mucocutaneous diseases. This review exhibits the process of EB virus infection and summarizes the clinical manifestations and varied prognosis of EB virus-associated skin diseases. The cases of common skin diseases including psoriasis, dermatomyositis, pemphigus, pemphigoid, parapsoriasis, atopic dermatitis, urticaria, systemic lupus erythematosus, scleroderma, panniculitis,erythema multiforme and vasculitis coinciding with EB virus infection were collected for the analysis of their EB virus-associated complications, treatments and outcomes. Read More

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Interleukin (IL)-13/IL-22/IL-31 skewing within the skin-homing T-cell population in papuloerythroderma.

J Dermatol 2021 Sep 18;48(9):1357-1364. Epub 2021 May 18.

Department of Dermatology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.

Papuloerythroderma (PEO) is a representative form of senile erythroderma with an unclear pathogenesis. This study aimed to characterize the T-cell phenotypes responsible for the pathogenesis of PEO. Cytokine profiles and cutaneous lymphocyte antigen (CLA) expression on circulating T lymphocytes in patients with PEO were simultaneously analyzed using flow cytometry. Read More

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September 2021

Biophysical and ultrasonographic changes in early patch/plaque stage of mycosis fungoides, compared with uninvolved skin.

Skin Res Technol 2021 Nov 11;27(6):1029-1034. Epub 2021 May 11.

Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran.

Background: The goal of this study was evaluation of the skin biophysical properties in early patch/plaque stage of mycosis fungoides (MF) and its comparison with uninvolved skin in order to gain a better understanding of the pathogenesis of diseases.

Materials And Methods: The stratum corneum hydration, transepidermal water loss (TEWL), surface friction, pH, sebum, melanin, erythema, temperature, elasticity parameters (R0, R2, R5), thickness, and echo density of epidermis and dermis were measured on lesions of 21 patients and compared with controls (average measures of uninvolved perilesional and symmetrical skins) by paired sample t test.

Results: Stratum corneum hydration (P < 0. Read More

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November 2021

Rhabdomyomatous mesenchymal hamartoma presenting as telangiectasia in a 57-year-old man.

J Cutan Pathol 2021 Sep 4;48(9):1182-1184. Epub 2021 Jun 4.

Razi Laboratory, Rasht, Iran.

Rhabdomyomatous mesenchymal hamartoma (RMH) is a rare congenital malformation of the dermis and subcutaneous tissue. Usually, RMH occurs in the midline of the face and neck region. We described a case of RMH presenting as telangiectasia in a 57-year-old man with a history of pityriasis lichenoides chronicus. Read More

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September 2021