1,132 results match your criteria Parapsoriasis
Gac Med Mex 2018 ;154(Supp 2):S41-S49
Unidad de Fototerapia. Hospital General Dr. Manuel Gea González, Ciudad de México, México.
Introduction: T-cell lymphoid dyscrasia is a group of different, infrequent, epitheliotropic inflammatory dermatosis that precede cutaneous T-cell lymphomas. Treatment with ultraviolet radiation is safe and efficacious.
Objective: To describe responses to treatment, secondary effects and complications. Read More
J Am Acad Dermatol 2018 Dec 3. Epub 2018 Dec 3.
Loyola Univ Medical Center Dermatology, 321 N La Grange Rd, La Grange Park, IL. Electronic address:
•Active cancers and inflammation increase the risk for venous thromboembolism. It is unknown whether this applies to mycosis fungoides and parapsoriasis.•Patients with mycosis fungoides and parapsoriasis have increased risk for venous thromboembolism. Read More
Br J Dermatol 2018 Sep 30. Epub 2018 Sep 30.
Dermatology Department, AP-HP Hôpital Saint-Louis, Paris.
The erythrodermic ulcerated form of mycosis fungoides (MF) is exceptional, and treatment of refractory cases is therefore very challenging. Brentuximab Vedotin (BV) is a monoclonal antibody combined with monomethyl auristatin E, recently approved for the treatment of refractory cutaneous T-cell lymphoma with CD30 expression. We report in this article a case of refractory MF in a 56 year-old man with a long story of large plaque parapsoriasis, as revealed by a psoriasiform erythroderma, treated initially with CHOP (cyclophosphamide, doxorubicine, vincristine and prednisone) polychemotherapy inducing a two year complete response. Read More
Photodermatol Photoimmunol Photomed 2018 Sep 29. Epub 2018 Sep 29.
Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Graz, Austria.
Background: Medical phototherapy can lead to the manifestation of polymorphic light eruption (PLE), though little is known about the frequency of such events.
Aims: The aim of this Austrian single center study was to retrospectively investigate over a 4-year time period the frequency of PLE in patients prone to the condition and patients with other diseases under phototherapy (mainly narrow-band and broad-band UVB).
Materials And Methods: The data for analysis were obtained from the electronic health and patient record database and patient files of the Photodermatology Unit, Department of Dermatology, Medical University of Graz, Austria. Read More
J Am Acad Dermatol 2018 Sep 17. Epub 2018 Sep 17.
Department of Dermatology and Medicine, University of Florida College of Medicine, Gainesville, FL.
Acquired hypopigmented skin changes are commonly encountered by dermatologists. Although hypopigmentation is often asymptomatic and benign, occasional serious and disabling conditions present with cutaneous hypopigmentation. A thorough history and physical examination, centered on disease distribution and morphological findings, can aid in delineating the causes of acquired hypopigmented disorders. Read More
Acta Derm Venereol 2018 Oct;98(9):898-899
Department of Virology, University of Helsinki, P.O. Box 21, FIN-00014 Helsinki, Finland.
Indian J Dermatol Venereol Leprol 2018 Jul-Aug;84(4):441-442
Escola de Saúde Pública do Estado do Rio Grande do Sul, Ambulatório de Dermatologia Sanitária, Porto Alegre - RS, Brazil.
Pan Afr Med J 2018 12;29:25. Epub 2018 Jan 12.
Centre d'Anatomopathologie Hassane, Rabat, Maroc.
Pityriasis lichenoides is a rare inflammatory dermatosis occurring in young subjects. It evolves into rashes on the trunk and the limbs which regress spontaneously. We here report a particular case of pityriasis lichenoides whose diagnosis was adjusted due to the scar appearance of the lesions. Read More
Indian J Dermatol Venereol Leprol 2018 Jul-Aug;84(4):442-443
Department of Medical, Surgical and Neurosciences, Division of Dermatology, University of Siena, Siena, Italy.
Clin Exp Dermatol 2018 Aug 23;43(6):703-707. Epub 2018 May 23.
Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan.
Although numerous infective agents, including varicella zoster virus (VZV), have been described in association with pityriasis lichenoides et varioliformis acuta (PLEVA) and pityriasis lichenoides chronica (PLC), none has been identified consistently in these lesions. We sought to immunohistochemically identify VZV glycoprotein (g)E antigens in the vascular endothelium in PLEVA and PLC lesions, based on our previous observation that gE was detected in the vascular endothelium and eccrine unit up until 2 months and 2.5, respectively, years after herpes zoster (HZ) infection. Read More
Sci Rep 2018 May 23;8(1):8051. Epub 2018 May 23.
Department of Dermatology, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Rd., Jing'an District, Shanghai, China.
Psoriasis and parapsoriasis en plaques are chronic inflammatory skin diseases, both representing therapeutic challenge in daily practice and adversely affecting the quality of life. Reactive oxygen species (ROS) has been evidenced to be involved in the pathogenesis of the chronic inflammatory diseases. We now report that hydrogen water, an effective ROS scavenger, has significant and rapid improvement in disease severity and quality of life for patients with psoriasis and parapsoriasis en plaques. Read More
Dermatol Online J 2017 Nov 15;23(11). Epub 2017 Nov 15.
Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York.
Background: Lymphomatoid drug reactions can mimic endogenous T and B cell lymphoproliferative diseases.
Objectives: We present a novel form of cutaneous drug reaction with features of pityriasis lichenoides (PL), a recognized form of T cell dyscrasia.
Methods: Ten cases were studied where a cutaneous eruption exhibiting semblance to PL within a few weeks to months after starting a particular drug. Read More
Indian Dermatol Online J 2018 Jan-Feb;9(1):40-43
Department of Pathology, VPS Lakeshore Hospital, Cochin, Kerala, India.
To present and discuss a novel association between branch duct-type intraductal papillary mucinous neoplasm and paraneoplastic parapsoriasis. We present the case of a middle-aged male presenting with skin lesions that were suggestive of parapsoriasis, resistant to treatment, and in whom a diagnosis of branch-type intraductal papillary mucinous neoplasm of the pancreas was eventually made. A curative Whipple's surgery led to complete resolution of the skin lesions within 3 weeks. Read More
Clin Exp Dermatol 2018 Jun 19;43(4):404-409. Epub 2018 Jan 19.
Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.
Background: Plasmacytoid dendritic cells (pDCs) and their product, type I interferons (IFNs), have been implicated in the pathogenesis of several skin disorders characterized by an interface dermatitis (ID) pattern, such as lichen planus (LP). A type I IFN signature has previously been documented in pityriasis lichenoides (PL). Although pDCs are known to be the main source and most potent producers of local type I IFNs, their role in PL has not been investigated. Read More
Pediatr Dermatol 2018 Mar 9;35(2):213-219. Epub 2018 Jan 9.
Department of Dermatology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Background/objectives: Pityriasis lichenoides is an uncommon papulosquamous disorder of unknown etiology. The objective of this study was to review the clinical features and treatment responses of individuals with pityriasis lichenoides seen at a tertiary referral center.
Methods: Seventy-five patients diagnosed with pityriasis lichenoides between 1997 and 2013 were reviewed, and 46 had long-term follow-up via telephone interviews. Read More
BMJ Case Rep 2018 Jan 4;2018. Epub 2018 Jan 4.
Pediatric Department, Hospital of Divino Espírito Santo of Ponta Delgada, Ponta Delgada - São Miguel, Azores, Portugal.
Coeliac disease (CD) is an autoimmune disease, characterised by a permanent sensitivity to gluten. It is being progressively recognised as a multisystemic disease, with multiple extraintestinal manifestations. Skin conditions (eg, dermatitis herpetiformis) are an example of its manifestations; however, its underlying mechanisms are still not well understood. Read More
Am J Dermatopathol 2018 Jun;40(6):409-415
Departments of Dermatology.
Background: Several cases of pityriasis lichenoides (PL) have been reported to evolve into mycosis fungoides (MF).
Objective: To elucidate clues to this progression.
Methods: Fifty-eight patients with PL between 2000 and 2013 (follow-up: 3-16 years, average: 8. Read More
J Am Acad Dermatol 2018 Jun 1;78(6):1077-1083.e4. Epub 2017 Dec 1.
Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
Background: Mycosis fungoides (MF) and parapsoriasis are characterized by malignant proliferation and chronic inflammation, which may affect the risk for venous thromboembolism (VTE).
Objectives: To examine the risk for VTE in patients with MF and parapsoriasis.
Methods: We conducted a nationwide population-based cohort study in Denmark to examine the relative risk (RR) of VTE in 525 patients with MF and 634 patients with parapsoriasis compared with that in sex- and age-matched controls from the general population. Read More
Pediatr Dermatol 2017 Sep;34(5):e265-e270
Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
A 5-year-old girl with T-cell acute lymphoblastic leukemia (T-ALL) developed a progressive eruption of crusted papules and ulcerative plaques involving 80% of her body surface area with histopathology consistent with febrile ulceronecrotic Mucha-Habermann disease (FUMHD), although multiple specimens also contained clonal leukemic cells. Her skin disease was refractory to many classic treatments for FUMHD, including methotrexate, and became so severe that concern about superinfection prevented intensification of chemotherapy for her malignancy. The addition of basiliximab promoted gradual improvement of the skin, allowing for chemotherapy intensification and subsequent bone marrow transplantation, after which the eruption resolved completely. Read More
Int J Womens Dermatol 2017 Jun 30;3(2):100-106. Epub 2017 Jan 30.
Department of Dermatology, Faculty of Medicine, Hospital Hassan II, Fez, Morocco.
Background: Mycosis fungoides (MF) is a significant diagnostic challenge; it has various differential diagnosis especially at an early stage. Our aim was to describe mimics of MF clinically and histologically, and to define significant diagnostic criteria of the disease.
Methods: This was a retro-prospective cohort of 370 patients in whom the diagnosis of MF was suspected clinically. Read More
Chin Med J (Engl) 2017 02;130(4):501-502
Department of Dermatology, Peking Union Medical College Hospital, Beijing 100730, China.
Acta Derm Venereol 2017 Jun;97(6):685-691
Department of Dermatology and Allergology, University of Helsinki, and Helinki University Hospital, FIN-00250 Helsinki, Finland.
Staphylococcal enterotoxins have been shown to promote lymphoma-associated immune dysregulation. This study examined changes in the skin microbiome of parapsoriasis compared with intact skin. Swab microbiome specimens were taken of the parapsoriasis lesions of 13 patients. Read More
Pediatr Dermatol 2017 Mar 30;34(2):150-155. Epub 2017 Jan 30.
Department of Dermatology, Alder Hey Children's Hospital, Liverpool, UK.
Background: Phototherapy is a well-recognized treatment in adults and children. Previous articles have reported success in treating recalcitrant skin disorders such as atopic dermatitis (AD), psoriasis, pityriasis lichenoides chronica, and vitiligo in children.
Methods: This was a retrospective review over an 18-month period from June 2012 to December 2013 of all children receiving phototherapy in a tertiary pediatric dermatology center. Read More
Clin Exp Dermatol 2017 Apr 23;42(3):303-305. Epub 2017 Jan 23.
Dermatology Department, Hospital Universitario Sanitas La Zarzuela, Universidad Francisco de Vitoria, Madrid, Spain.
Pityriasis lichenoides chronica (PLC) is an infrequent dermatosis of unknown aetiology, wholse evolution and response to treatment differs between children and adults. When PLC is recalcitrant or unresponsive to topical treatment, phototherapy is one of the main treatments used. We carried out a prospective study of adult diffuse PLC treated with narrowband ultraviolet B (NB-UVB). Read More
Rev Med Chil 2016 Sep;144(9):1214-1217
Anatomía Patológica, Hospital Clínico San Borja Arriarán, Universidad de Chile, Santiago, Chile.
Pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC) and febrile ulceronecrotic Mucha-Habermann disease (FUMHD) are considered different manifestations of the same disease. Febrile ulceronecrotic Mucha-Habermann disease is a rare, and potentially lethal illness which is characterized by fast progression of numerous papules that converge, ulcerate and form a plaque with a necrotic center, together with hemorrhagic vesicles and pustules that are associated with high fever and variable systemic symptoms. We report a 16 years old male presenting with erythematous papules with crusts and fever. Read More
Indian J Dermatol Venereol Leprol 2017 Mar-Apr;83(2):270-273
Department of Dermatology, Division of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.
Semin Diagn Pathol 2017 Jan 28;34(1):3-14. Epub 2016 Nov 28.
Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, 8036 Graz, Austria. Electronic address:
Primary cutaneous lymphomas represent a broad group of diseases with different clinical, histopathological, phenotypic, molecular, and prognostic features. All cutaneous lymphomas share the same tropism of neoplastic lymphocytes for the skin, but precise classification is paramount for proper management of the patients. Primary cutaneous lymphomas are classified according to the schemes proposed by the European Organization for Research and Treatment of Cancer (EORTC)-Cutaneous Lymphomas Task Force together with the World Health Organization (WHO) in 2005, and the WHO classification of 2008 with the 2016 update. Read More
Clin Dermatol 2016 Sep-Oct;34(5):633-9. Epub 2016 May 24.
Harvard Medical School, Dermatology Program, Division of Allergy and Immunology, Department of Medicine, Boston Children's Hospital, Boston, MA. Electronic address:
Phototherapy can be a safe and effective treatment for various skin diseases in children. Special considerations governing the use of this treatment modality in pediatric populations include patient, family, and facility-based factors that are oriented around heightened concerns with regard to safety and tolerability of treatment. Although phototherapy has been found to be effective in a wide range of dermatologic conditions affecting pediatric populations, including psoriasis, atopic dermatitis, pityriasis lichenoides, cutaneous T-cell lymphoma, and vitiligo, there is need for additional research on other conditions in which phototherapy has shown promise. Read More
Dermatol Online J 2016 May 15;22(5). Epub 2016 May 15.
Marmara University, School of Medicine, Department of Dermatology, Istanbul.
Keratitis-ichthyosis-deafness (KID) syndrome is a rare genodermatosis causing ichthyosis-like skin lesions, keratitis, and deafness. Herein, we report a patient with this rare syndrome in association with pityriasis lichenoides chronica, which was succesfully treated with narrow-band ultraviolet B phototherapy despite our concerns regarding the increased risk of squamous cell carcinoma, hyperpyrexia, and keratitis. Read More
Ann Emerg Med 2016 Sep;68(3):276-311
Department of Dermatology, Affiliated Third Hospital of Hangzhou, Anhui Medical University, Hangzhou, China.
Rom J Morphol Embryol 2016 ;57(2):539-46
Department of Dermatology, "Carol Davila" Central University Emergency Military Hospital, Bucharest, Romania;
Granulomatous slack skin (GSS) represents an extremely rare variant of mycosis fungoides with only 70 cases reported in the literature to date. It is characterized clinically by the occurrence of bulky, pendulous skinfolds, usually located in flexural areas and histologically by an infiltrate composed of small neoplastic T-lymphocytes joined by granulomatous inflammation with scattered multinucleated giant cells containing nuclei arranged in a wreath-like fashion. Since its first description, very rare cases of GSS with muscle involvement, large vessels involvement, or necrobiotic changes have been reported. Read More
Am J Clin Dermatol 2016 Dec;17(6):583-591
Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., Miami, FL, 33136, USA.
Background: Pityriasis lichenoides (PL) is a dermatologic disorder that manifests in either the acute (pityriasis lichenoides et varioliformis acuta) or the chronic form (pityriasis lichenoides chronica, also known as parapsoriasis chronica). Traditional first-line therapy consists of corticosteroids or antibiotics; however, these treatments are often accompanied with multiple side effects and may be ineffective.
Objective: The goal of this study was to review the use of phototherapy for treating PL in the pediatric population. Read More
Int J Dermatol 2016 Nov;55(11):1205-1209
ExpressMed Laboratories, Kingdom of Bahrain.
Background: Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare fulminant variant of pityriasis lichenoides et varioliformis acuta (PLEVA) characterized by a rapidly progressive course with predominant ulceronecrotic lesions associated with fever and systemic manifestations. First described by Degos in 1966, it carries a high morbidity and is potentially fatal. The exact pathogenesis is not clear, but it is proposed to be the result of hypersensitivity reaction to an infection. Read More
Med Clin (Barc) 2016 Dec 24;147(12):564. Epub 2016 Jun 24.
Servicio de Reumatología, Hospital Universitario San Cecilio, Granada, España.
J Eur Acad Dermatol Venereol 2016 Sep 26;30(9):1497-502. Epub 2016 Jun 26.
Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
Background: Cutaneous T-cell lymphomas (CTCL) are skin malignancies including mycosis fungoides (MF) and CD30(+) lymphoproliferative disorders (LPD). In early disease, CTCL can be difficult to diagnose, especially in MF for which there is no reliable diagnostic marker. MF/CTCL have increased expression of thymocyte selection-associated HMG box protein (TOX). Read More
J Pediatr 2016 Sep 11;176:211-211.e1. Epub 2016 Jun 11.
Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.
Cutis 2016 May;97(5):345;347;358
Bay Dermatology/Largo Medical Center, Florida, USA.
Pityriasis lichenoides is an uncommon, acquired, idiopathic, self-limiting skin disease that poses a challenge to patients and clinicians to diagnose and treat. Several variants exist including pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC), and febrile ulcer-onecrotic Mucha-Habermann disease. Precise classification can be difficult due to an overlap of clinical and histologic features. Read More
Int J Dermatol 2016 Sep 3;55(9):1027-9. Epub 2016 Jun 3.
Department of Dermatology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia.
Expert Rev Anti Infect Ther 2016 06;14(6):601-11
c School of Public Health and Primary Care , The Chinese University of Hong Kong and Prince of Wales Hospital , Shatin , Hong Kong.
Introduction: Paraviral exanthems are skin diseases suspected to be caused by viruses, with a single virus-exanthem relationship not universally accepted. Although most paraviral exanthems are self-remitting, accurate diagnoses are important as some patients might develop complications. Some of the differential diagnoses might cause serious complications, and some paraviral exanthems might lead to complications for at-risk groups such as pregnant women. Read More
Br J Dermatol 2016 Dec 6;175(6):1274-1283. Epub 2016 Sep 6.
Dermatology Department, Coimbra University Hospital Centre, Coimbra, Portugal.
Background: Inpatients with cutaneous adverse drug reactions (CADR) with overlapping features between maculopapular exanthema (MPE) and drug reaction with eosinophilia and systemic symptoms (DRESS) were examined.
Objectives: To characterize patients with exanthema and few systemic symptoms not meeting the criteria for DRESS [overlapping MPE-DRESS (MP/DR)].
Methods: We undertook a comparative analysis of clinical and laboratory features of patients with MPE, MP/DR and DRESS (2008-12). Read More
Int J Dermatol 2016 Oct 7;55(10):1115-8. Epub 2016 Apr 7.
Temple University School of Medicine, Philadelphia, PA, USA.
Background: Certain dermatologic conditions are known to show seasonal variations in frequency, the reasons for which are unclear but in some cases may be attributable to changes in ambient weather conditions.
Objectives: The current study was conducted to determine whether seasonal trends might exist for dermatologic conditions including erythema multiforme, guttate psoriasis, erythema dyschromicum perstans (ashy dermatosis), pityriasis lichenoides, and pityriasis rosea.
Methods: Data were derived from a 15-year retrospective review of electronic records from a large dermatopathology laboratory located in the mid-Atlantic region of the USA. Read More
Practitioner 2016 Feb;260(1790):23-6, 3
There is no standard definition regarding the severity of psoriasis, and a number of factors should be considered, including the extent and stability of skin disease, involvement of joints, response to treatment, and impact on quality of life. Erythrodermic psoriasis and pustular psoriasis are severe conditions and the patient may be systemically unwell and febrile. NICE recommends that four key areas should be evaluated and recorded when assessing patients: severity, using the static Physician's Global Assessment (sPGA); disease impact on physical, psychological and social wellbeing using the Dermatology Life Quality Index (DLQI); the presence of psoriatic arthritis; and comorbidities. Read More
Br J Dermatol 2016 Oct 20;175(4):807-9. Epub 2016 Jun 20.
Department of Dermatology, University of Toronto, Toronto, ON, Canada.
Eur J Dermatol 2016 Jun;26(3):300-2
Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Italy.
Ann Dermatol Venereol 2016 Apr 14;143(4):311-7. Epub 2016 Mar 14.
Département de pathologie, hôpital Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
Indian Dermatol Online J 2015 Dec;6(Suppl 1):S24-6
Department of Dermatology, Goztepe Research and Training Hospital, Istanbul Medeniyet University, Istanbul, Turkey.
Lymphomatoid contact dermatitis (LCD) is a rare variant of noneczematous allergic contact dermatitis, which can mimick parapsoriasis or early-stage mycosis fungoides with its atypical clinical and histopathological manifestation. Many different haptens have been reported to be associated with this reaction. Histopathological examination, immunhistochemistry, clonality tests, and patch tests are mandatory for diagnosis and differential diagnosis. Read More
J Dtsch Dermatol Ges 2016 Feb 20;14(2):184-6. Epub 2016 Jan 20.
Department of Dermatology, Venereology, and Allergology, HELIOS St. Elisabeth Hospital, Oberhausen. Germany.
J Immunol Res 2015 16;2015:856340. Epub 2015 Dec 16.
Uludag University School of Medicine, Department of Dermatology and Venereology, Bursa, Turkey.
We retrospectively analyzed the clinicopathological correlation and prognostic value of cell surface antigens expressed by peripheral blood mononuclear cells in patients with mycosis fungoides (MF). 121 consecutive MF patients were included in this study. All patients had peripheral blood flow cytometry as part of their first visit. Read More
Acta Derm Venereol 2016 Jun;96(5):669-73
Section of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Skåne University Hospital, SE-221 85 Lund, Sweden.
Mycosis fungoides (MF) is a primary cutaneous T-cell lymphoma with slow disease progression. There is a lack of descriptive data from Sweden concerning patients with this diagnosis. This study extracted data on patients admitted to the dermatology department at Lund University Hospital, Sweden from 1996 to 2010. Read More
Przegl Lek 2016;73(7):452-9
Introduction: Primary cutaneous
lymphomas are lymphoproliferative
skin infiltrates of T-, B- or NK-cells,
classified according to the World
Health Organization - European Organization
of the Research and Treatment
of Cancer (WHO-EORTC) criteria. They
are the second most common group of
extranodal non-Hodgkin lymphomas,
that present in the skin with no evidence
of systemic involvement at the
time of diagnosis.
Aims: The aim of the study was the analysis of clinical profile of cutaneous lymphomas in the tertiary referral center in Poland. Read More