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    [Pityriasis lichenoides: not always a clear-cut diagnosis!]
    Pan Afr Med J 2018 12;29:25. Epub 2018 Jan 12.
    Centre d'Anatomopathologie Hassane, Rabat, Maroc.
    Pityriasis lichenoides is a rare inflammatory dermatosis occurring in young subjects. It evolves into rashes on the trunk and the limbs which regress spontaneously. We here report a particular case of pityriasis lichenoides whose diagnosis was adjusted due to the scar appearance of the lesions. Read More

    Positive effects of hydrogen-water bathing in patients of psoriasis and parapsoriasis en plaques.
    Sci Rep 2018 May 23;8(1):8051. Epub 2018 May 23.
    Department of Dermatology, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Rd., Jing'an District, Shanghai, China.
    Psoriasis and parapsoriasis en plaques are chronic inflammatory skin diseases, both representing therapeutic challenge in daily practice and adversely affecting the quality of life. Reactive oxygen species (ROS) has been evidenced to be involved in the pathogenesis of the chronic inflammatory diseases. We now report that hydrogen water, an effective ROS scavenger, has significant and rapid improvement in disease severity and quality of life for patients with psoriasis and parapsoriasis en plaques. Read More

    Pityriasis lichenoides-like drug reaction: A clinical histopathologic study of 10 cases.
    Dermatol Online J 2017 Nov 15;23(11). Epub 2017 Nov 15.
    Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York.
    Background: Lymphomatoid drug reactions can mimic endogenous T and B cell lymphoproliferative diseases.

    Objectives: We present a novel form of cutaneous drug reaction with features of pityriasis lichenoides (PL), a recognized form of T cell dyscrasia.

    Methods: Ten cases were studied where a cutaneous eruption exhibiting semblance to PL within a few weeks to months after starting a particular drug. Read More

    Branch Duct-type Intraductal Papillary Mucinous Neoplasm Presenting as Paraneoplastic Small Plaque Para-psoriasis.
    Indian Dermatol Online J 2018 Jan-Feb;9(1):40-43
    Department of Pathology, VPS Lakeshore Hospital, Cochin, Kerala, India.
    To present and discuss a novel association between branch duct-type intraductal papillary mucinous neoplasm and paraneoplastic parapsoriasis. We present the case of a middle-aged male presenting with skin lesions that were suggestive of parapsoriasis, resistant to treatment, and in whom a diagnosis of branch-type intraductal papillary mucinous neoplasm of the pancreas was eventually made. A curative Whipple's surgery led to complete resolution of the skin lesions within 3 weeks. Read More

    Risk of venous thromboembolism in patients with mycosis fungoides and parapsoriasis: A Danish nationwide population-based cohort study.
    J Am Acad Dermatol 2018 Jun 1;78(6):1077-1083.e4. Epub 2017 Dec 1.
    Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
    Background: Mycosis fungoides (MF) and parapsoriasis are characterized by malignant proliferation and chronic inflammation, which may affect the risk for venous thromboembolism (VTE).

    Objectives: To examine the risk for VTE in patients with MF and parapsoriasis.

    Methods: We conducted a nationwide population-based cohort study in Denmark to examine the relative risk (RR) of VTE in 525 patients with MF and 634 patients with parapsoriasis compared with that in sex- and age-matched controls from the general population. Read More

    Severe Mucha-Habermann-Like Ulceronecrotic Skin Disease in T-Cell Acute Lymphoblastic Leukemia Responsive to Basiliximab and Stem Cell Transplant.
    Pediatr Dermatol 2017 Sep;34(5):e265-e270
    Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
    A 5-year-old girl with T-cell acute lymphoblastic leukemia (T-ALL) developed a progressive eruption of crusted papules and ulcerative plaques involving 80% of her body surface area with histopathology consistent with febrile ulceronecrotic Mucha-Habermann disease (FUMHD), although multiple specimens also contained clonal leukemic cells. Her skin disease was refractory to many classic treatments for FUMHD, including methotrexate, and became so severe that concern about superinfection prevented intensification of chemotherapy for her malignancy. The addition of basiliximab promoted gradual improvement of the skin, allowing for chemotherapy intensification and subsequent bone marrow transplantation, after which the eruption resolved completely. Read More

    Defining the mimics and clinico-histological diagnosis criteria for mycosis fungoides to minimize misdiagnosis.
    Int J Womens Dermatol 2017 Jun 30;3(2):100-106. Epub 2017 Jan 30.
    Department of Dermatology, Faculty of Medicine, Hospital Hassan II, Fez, Morocco.
    Background: Mycosis fungoides (MF) is a significant diagnostic challenge; it has various differential diagnosis especially at an early stage. Our aim was to describe mimics of MF clinically and histologically, and to define significant diagnostic criteria of the disease.

    Methods: This was a retro-prospective cohort of 370 patients in whom the diagnosis of MF was suspected clinically. Read More

    Skin Microbiome in Small- and Large-plaque Parapsoriasis.
    Acta Derm Venereol 2017 Jun;97(6):685-691
    Department of Dermatology and Allergology, University of Helsinki, and Helinki University Hospital, FIN-00250 Helsinki, Finland.
    Staphylococcal enterotoxins have been shown to promote lymphoma-associated immune dysregulation. This study examined changes in the skin microbiome of parapsoriasis compared with intact skin. Swab microbiome specimens were taken of the parapsoriasis lesions of 13 patients. Read More

    Use of Phototherapy in Children.
    Pediatr Dermatol 2017 Mar 30;34(2):150-155. Epub 2017 Jan 30.
    Department of Dermatology, Alder Hey Children's Hospital, Liverpool, UK.
    Background: Phototherapy is a well-recognized treatment in adults and children. Previous articles have reported success in treating recalcitrant skin disorders such as atopic dermatitis (AD), psoriasis, pityriasis lichenoides chronica, and vitiligo in children.

    Methods: This was a retrospective review over an 18-month period from June 2012 to December 2013 of all children receiving phototherapy in a tertiary pediatric dermatology center. Read More

    Treatment of adult diffuse pityriasis lichenoides chronica with narrowband ultraviolet B: experience and literature review.
    Clin Exp Dermatol 2017 Apr 23;42(3):303-305. Epub 2017 Jan 23.
    Dermatology Department, Hospital Universitario Sanitas La Zarzuela, Universidad Francisco de Vitoria, Madrid, Spain.
    Pityriasis lichenoides chronica (PLC) is an infrequent dermatosis of unknown aetiology, wholse evolution and response to treatment differs between children and adults. When PLC is recalcitrant or unresponsive to topical treatment, phototherapy is one of the main treatments used. We carried out a prospective study of adult diffuse PLC treated with narrowband ultraviolet B (NB-UVB). Read More

    [Febrile ulceronecrotic Mucha-Habermann disease].
    Rev Med Chil 2016 Sep;144(9):1214-1217
    Anatomía Patológica, Hospital Clínico San Borja Arriarán, Universidad de Chile, Santiago, Chile.
    Pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC) and febrile ulceronecrotic Mucha-Habermann disease (FUMHD) are considered different manifestations of the same disease. Febrile ulceronecrotic Mucha-Habermann disease is a rare, and potentially lethal illness which is characterized by fast progression of numerous papules that converge, ulcerate and form a plaque with a necrotic center, together with hemorrhagic vesicles and pustules that are associated with high fever and variable systemic symptoms. We report a 16 years old male presenting with erythematous papules with crusts and fever. Read More

    Past, present and future of cutaneous lymphomas.
    Semin Diagn Pathol 2017 Jan 28;34(1):3-14. Epub 2016 Nov 28.
    Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, 8036 Graz, Austria. Electronic address:
    Primary cutaneous lymphomas represent a broad group of diseases with different clinical, histopathological, phenotypic, molecular, and prognostic features. All cutaneous lymphomas share the same tropism of neoplastic lymphocytes for the skin, but precise classification is paramount for proper management of the patients. Primary cutaneous lymphomas are classified according to the schemes proposed by the European Organization for Research and Treatment of Cancer (EORTC)-Cutaneous Lymphomas Task Force together with the World Health Organization (WHO) in 2005, and the WHO classification of 2008 with the 2016 update. Read More

    Phototherapy in children: Considerations and indications.
    Clin Dermatol 2016 Sep-Oct;34(5):633-9. Epub 2016 May 24.
    Harvard Medical School, Dermatology Program, Division of Allergy and Immunology, Department of Medicine, Boston Children's Hospital, Boston, MA. Electronic address:
    Phototherapy can be a safe and effective treatment for various skin diseases in children. Special considerations governing the use of this treatment modality in pediatric populations include patient, family, and facility-based factors that are oriented around heightened concerns with regard to safety and tolerability of treatment. Although phototherapy has been found to be effective in a wide range of dermatologic conditions affecting pediatric populations, including psoriasis, atopic dermatitis, pityriasis lichenoides, cutaneous T-cell lymphoma, and vitiligo, there is need for additional research on other conditions in which phototherapy has shown promise. Read More

    Successful treatment of pityriasis lichenoides chronica with narrow-band ultraviolet B therapy in a patient with Keratitis-Ichthyosis-Deafness syndrome: a case report.
    Dermatol Online J 2016 May 15;22(5). Epub 2016 May 15.
    Marmara University, School of Medicine, Department of Dermatology, Istanbul.
    Keratitis-ichthyosis-deafness (KID) syndrome is a rare genodermatosis causing ichthyosis-like skin lesions, keratitis, and deafness. Herein, we report a patient with this rare syndrome in association with pityriasis lichenoides chronica, which was succesfully treated with narrow-band ultraviolet B phototherapy despite our concerns regarding the increased risk of squamous cell carcinoma, hyperpyrexia, and keratitis. Read More

    Granulomatous slack skin - seven years follow-up of a case with features of "parapsoriasis en plaques", muscle involvement, granulomatous vasculitis, and necrobiotic changes.
    Rom J Morphol Embryol 2016 ;57(2):539-46
    Department of Dermatology, "Carol Davila" Central University Emergency Military Hospital, Bucharest, Romania;
    Granulomatous slack skin (GSS) represents an extremely rare variant of mycosis fungoides with only 70 cases reported in the literature to date. It is characterized clinically by the occurrence of bulky, pendulous skinfolds, usually located in flexural areas and histologically by an infiltrate composed of small neoplastic T-lymphocytes joined by granulomatous inflammation with scattered multinucleated giant cells containing nuclei arranged in a wreath-like fashion. Since its first description, very rare cases of GSS with muscle involvement, large vessels involvement, or necrobiotic changes have been reported. Read More

    Phototherapy for Pityriasis Lichenoides in the Pediatric Population: A Review of the Published Literature.
    Am J Clin Dermatol 2016 Dec;17(6):583-591
    Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., Miami, FL, 33136, USA.
    Background: Pityriasis lichenoides (PL) is a dermatologic disorder that manifests in either the acute (pityriasis lichenoides et varioliformis acuta) or the chronic form (pityriasis lichenoides chronica, also known as parapsoriasis chronica). Traditional first-line therapy consists of corticosteroids or antibiotics; however, these treatments are often accompanied with multiple side effects and may be ineffective.

    Objective: The goal of this study was to review the use of phototherapy for treating PL in the pediatric population. Read More

    Febrile ulceronecrotic Mucha-Habermann disease in an 8-year-old boy responding to methotrexate.
    Int J Dermatol 2016 Nov;55(11):1205-1209
    ExpressMed Laboratories, Kingdom of Bahrain.
    Background: Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare fulminant variant of pityriasis lichenoides et varioliformis acuta (PLEVA) characterized by a rapidly progressive course with predominant ulceronecrotic lesions associated with fever and systemic manifestations. First described by Degos in 1966, it carries a high morbidity and is potentially fatal. The exact pathogenesis is not clear, but it is proposed to be the result of hypersensitivity reaction to an infection. Read More

    TOX expression and role in CTCL.
    J Eur Acad Dermatol Venereol 2016 Sep 26;30(9):1497-502. Epub 2016 Jun 26.
    Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
    Background: Cutaneous T-cell lymphomas (CTCL) are skin malignancies including mycosis fungoides (MF) and CD30(+) lymphoproliferative disorders (LPD). In early disease, CTCL can be difficult to diagnose, especially in MF for which there is no reliable diagnostic marker. MF/CTCL have increased expression of thymocyte selection-associated HMG box protein (TOX). Read More

    Pityriasis lichenoides chronica presenting with bilateral palmoplantar involvement.
    Cutis 2016 May;97(5):345;347;358
    Bay Dermatology/Largo Medical Center, Florida, USA.
    Pityriasis lichenoides is an uncommon, acquired, idiopathic, self-limiting skin disease that poses a challenge to patients and clinicians to diagnose and treat. Several variants exist including pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC), and febrile ulcer-onecrotic Mucha-Habermann disease. Precise classification can be difficult due to an overlap of clinical and histologic features. Read More

    Paraviral exanthems.
    Expert Rev Anti Infect Ther 2016 06;14(6):601-11
    c School of Public Health and Primary Care , The Chinese University of Hong Kong and Prince of Wales Hospital , Shatin , Hong Kong.
    Introduction: Paraviral exanthems are skin diseases suspected to be caused by viruses, with a single virus-exanthem relationship not universally accepted. Although most paraviral exanthems are self-remitting, accurate diagnoses are important as some patients might develop complications. Some of the differential diagnoses might cause serious complications, and some paraviral exanthems might lead to complications for at-risk groups such as pregnant women. Read More

    Overlap between maculopapular exanthema and drug reaction with eosinophilia and systemic symptoms among cutaneous adverse drug reactions in a dermatology ward.
    Br J Dermatol 2016 Dec 6;175(6):1274-1283. Epub 2016 Sep 6.
    Dermatology Department, Coimbra University Hospital Centre, Coimbra, Portugal.
    Background: Inpatients with cutaneous adverse drug reactions (CADR) with overlapping features between maculopapular exanthema (MPE) and drug reaction with eosinophilia and systemic symptoms (DRESS) were examined.

    Objectives: To characterize patients with exanthema and few systemic symptoms not meeting the criteria for DRESS [overlapping MPE-DRESS (MP/DR)].

    Methods: We undertook a comparative analysis of clinical and laboratory features of patients with MPE, MP/DR and DRESS (2008-12). Read More

    Seasonal variations in dermatologic and dermatopathologic diagnoses: a retrospective 15-year analysis of dermatopathologic data.
    Int J Dermatol 2016 Oct 7;55(10):1115-8. Epub 2016 Apr 7.
    Temple University School of Medicine, Philadelphia, PA, USA.
    Background: Certain dermatologic conditions are known to show seasonal variations in frequency, the reasons for which are unclear but in some cases may be attributable to changes in ambient weather conditions.

    Objectives: The current study was conducted to determine whether seasonal trends might exist for dermatologic conditions including erythema multiforme, guttate psoriasis, erythema dyschromicum perstans (ashy dermatosis), pityriasis lichenoides, and pityriasis rosea.

    Methods: Data were derived from a 15-year retrospective review of electronic records from a large dermatopathology laboratory located in the mid-Atlantic region of the USA. Read More

    Tailor systemic therapy to the patient with severe psoriasis.
    Practitioner 2016 Feb;260(1790):23-6, 3
    There is no standard definition regarding the severity of psoriasis, and a number of factors should be considered, including the extent and stability of skin disease, involvement of joints, response to treatment, and impact on quality of life. Erythrodermic psoriasis and pustular psoriasis are severe conditions and the patient may be systemically unwell and febrile. NICE recommends that four key areas should be evaluated and recorded when assessing patients: severity, using the static Physician's Global Assessment (sPGA); disease impact on physical, psychological and social wellbeing using the Dermatology Life Quality Index (DLQI); the presence of psoriatic arthritis; and comorbidities. Read More

    Lymphomatoid contact dermatitis associated with textile dye at an unusual location.
    Indian Dermatol Online J 2015 Dec;6(Suppl 1):S24-6
    Department of Dermatology, Goztepe Research and Training Hospital, Istanbul Medeniyet University, Istanbul, Turkey.
    Lymphomatoid contact dermatitis (LCD) is a rare variant of noneczematous allergic contact dermatitis, which can mimick parapsoriasis or early-stage mycosis fungoides with its atypical clinical and histopathological manifestation. Many different haptens have been reported to be associated with this reaction. Histopathological examination, immunhistochemistry, clonality tests, and patch tests are mandatory for diagnosis and differential diagnosis. Read More

    Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides.
    J Immunol Res 2015 16;2015:856340. Epub 2015 Dec 16.
    Uludag University School of Medicine, Department of Dermatology and Venereology, Bursa, Turkey.
    We retrospectively analyzed the clinicopathological correlation and prognostic value of cell surface antigens expressed by peripheral blood mononuclear cells in patients with mycosis fungoides (MF). 121 consecutive MF patients were included in this study. All patients had peripheral blood flow cytometry as part of their first visit. Read More

    Mycosis Fungoides: A Retrospective Study of 44 Swedish Cases.
    Acta Derm Venereol 2016 Jun;96(5):669-73
    Section of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Skåne University Hospital, SE-221 85 Lund, Sweden.
    Mycosis fungoides (MF) is a primary cutaneous T-cell lymphoma with slow disease progression. There is a lack of descriptive data from Sweden concerning patients with this diagnosis. This study extracted data on patients admitted to the dermatology department at Lund University Hospital, Sweden from 1996 to 2010. Read More

    Primary cutaneous lymphomas: the analysis of cases treated in the Department of Dermatology University Hospital in Krakow.
    Przegl Lek 2016;73(7):452-9
    Introduction: Primary cutaneous lymphomas are lymphoproliferative skin infiltrates of T-, B- or NK-cells, classified according to the World Health Organization - European Organization of the Research and Treatment of Cancer (WHO-EORTC) criteria. They are the second most common group of extranodal non-Hodgkin lymphomas, that present in the skin with no evidence of systemic involvement at the time of diagnosis.

    Aims: The aim of the study was the analysis of clinical profile of cutaneous lymphomas in the tertiary referral center in Poland. Read More

    Febrile ulceronecrotic Mucha-Habermann disease: proposed diagnostic criteria and therapeutic evaluation.
    Int J Dermatol 2016 Jul 23;55(7):729-38. Epub 2015 Dec 23.
    Department of Dermatology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
    Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare severe variant of pityriasis lichenoides et varioliformis acuta characterized clinically by aggressive ulceronecrotic skin lesions associated with high fever and histologically by features typical of pityriasis lichenoides et varioliformis acuta. Despite the continuous addition of new case reports, no definite diagnostic criteria have been established, and an optimum treatment is still waiting. Herein, we review the different aspects of this rare entity, including pathogenesis, clinical and histopathological features, differential diagnosis, course, prognosis, and outcome. Read More

    Successful therapy of cyclosporin A in pityriasis lichenoides et varioliformis acuta preceded by hand, foot and mouth disease.
    Antivir Ther 2016 15;21(3):273-5. Epub 2015 Dec 15.
    Department of Dermatology, School of Medicine, Medical University of Silesia, Katowice, Poland.
    To our knowledge, there are no previously published cases of enteroviral infection complicated by pityriasis lichenoides et varioliformis acuta (PLEVA). A 30-year-old woman is reported with a severe form of PLEVA, preceded by hand, foot and mouth disease. Immunosuppressive treatment with cyclosporin A resulted in rapid clinical improvement. Read More

    Febrile Ulceronecrotic Mucha-Habermann Disease: Two Cases with Excellent Response to Methotrexate.
    Pediatr Dermatol 2015 Nov-Dec;32(6):e307-8. Epub 2015 Oct 8.
    Department of Dermatology, Center for Health and Healing, Oregon Health and Science University, Portland, Oregon.
    Febrile ulceronecrotic Mucha-Habermann disease (FUMHD), a severe form of pityriasis lichenoides et varioliformis acuta (PLEVA), featuring large, ulcerative, necrotic skin plaques, high fever, and other systemic symptoms, is a rare disorder of unknown etiology. No randomized controlled trials have established treatment guidelines and multiple modalities are often employed, making it difficult to assess the efficacy of any single agent. We report two cases of this condition in which treatment with methotrexate plus antibiotic treatment for superinfection led to rapid improvement. Read More

    Risk of Acute Myocardial Infarction or Stroke in Patients with Mycosis Fungoides and Parapsoriasis.
    Acta Derm Venereol 2016 May;96(4):530-4
    Department of Dermatology, Aarhus University Hospital, P.P. Oerumsgade 11, DK-8000 Aarhus, Denmark.
    Mycosis fungoides (MF) and parapsoriasis display increased inflammation, which may be associated with increased risk of arterial cardiovascular events. The aim of this Danish nationwide population-based cohort study was to assess the relative risk (RR) of acute myocardial infarction (AMI) or stroke in patients with MF and parapsoriasis. In patients with MF, the RR of AMI or stroke was 1. Read More

    [Febrile ulceronecrotic Mucha-Habermann disease].
    Arch Pediatr 2016 Jan 6;23(1):82-5. Epub 2015 Nov 6.
    Service de pédiatrie générale, CHU Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France. Electronic address:
    Pityriasis lichenoides et varioliformis acuta (PLEVA) is an inflammatory skin disease that is unknown to pediatricians. The ulceronecrotic febrile form is a rare and potentially lethal variant. We report the case of a 7-year-old boy with a papulovesicular eruption lasting for 4 weeks, secondarily associated with ulcers and necrotic crusts, fever, and systemic signs. Read More

    Lichen striatus and pityriasis lichenoides chronica in an 11-year-old girl: An etiologic relationship?
    J Pak Med Assoc 2015 Sep;65(9):1011-3
    Department of Pathology, Turgut Ozal University, Faculty of Medicine, Ankara, Turkey.
    Lichen striatusis a rare linear papulardermatosis that primarily occurs in children. The lesions have a linear distribution following Blaschko's lines. Pityriasis lichenoides is an uncommon benign skin disorder with two major variants: acute and chronic. Read More

    Systemic involvement in mycosis fungoides.
    Clin Dermatol 2015 Sep-Oct;33(5):563-71. Epub 2015 Jun 1.
    Department of Dermatology, University of Zurich, Switzerland. Electronic address:
    Mycosis fungoides (MF) represents almost 50% of all primary cutaneous lymphomas and more than 70% of cutaneous T-cell lymphomas (CTCL). Arising from preferentially skin-homing lymphocytes with genetic instability, MF evolves through stages (IA-IVB), producing inconspicuous inflammatory features in the beginning and finally resulting in a proliferation of cytomorphologic, phenotypic, and genotypic abnormal tumor cells. Over the past 200 years, there has been much confusion in the classification of lymphomas due to semantic disagreements (MF, CTCL, parapsoriasis, lymphosarcoma, reticulum cell sarcoma, and many other terms), lack of diagnostic standard criteria, and new molecular diagnostic methods. Read More

    Pityriasis lichenoides et varioliformis acuta after influenza vaccine.
    An Bras Dermatol 2015 May-Jun;90(3 Suppl 1):181-4
    Hospital da Polícia Militar de Minas Gerais, Belo Horizonte, MG, BR.
    The etiology of pityriasis lichenoides is unknown. One of the accepted theories admits that PL is an inflammatory response to extrinsic antigens such as infectious agents, drugs and vaccines. In recent medical literature, only the MMR vaccine (Measles, Mumps and Rubella) was associated with the occurrence of this disease. Read More

    Multiple minute digitate hyperkeratosis--a peculiar entity.
    An Bras Dermatol 2015 May-Jun;90(3 Suppl 1):153-5
    Centro Hospitalar Universitário de Coimbra, Coimbra, PT.
    Multiple minute digitate hyperkeratosis is a rare, non-follicular dermatosis, with fewer than 30 cases described worldwide. It can be either acquired or inherited in an autosomal dominant pattern. We describe the case of an 83-year old patient with life-long, multiple, digitate, milimetric lesions, and a positive family history for the same dermatosis. Read More

    Frequency of hypopigmented mycosis fungoides in Egyptian patients presenting with hypopigmented lesions of the trunk.
    Am J Dermatopathol 2015 Nov;37(11):834-40
    *Dermatopathology Unit, Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt; Departments of †Pathology, and ‡Dermatology, National Research Centre, Cairo, Egypt.
    Hypopigmented mycosis fungoides (HMF) is an uncommon variant of mycosis fungoides with an unknown exact frequency. We aimed to study the frequency of HMF in a cohort of Egyptian patients presenting to a tertiary care center in Cairo, Egypt, with hypopigmented lesions of the trunk. Hundred patients with hypopigmented lesions involving the trunk (with or without other sites involvement) were subjected to thorough clinical and histopathological examination. Read More

    An observational study of cutaneous adverse drug reactions in a teaching hospital.
    Int J Clin Pharm 2015 Dec 4;37(6):996-9. Epub 2015 Aug 4.
    Department of Medicine and Preventive Cardiology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, 110062, India.
    Background: Pharmacotherapy is often impeded by adverse drug reactions (ADRs). Among these ADRs cutaneous reactions are the major class being easily identified and reported. If not noted early it has potential to develop into serious lesions. Read More

    [Pityriasis Lichenoides: Case report and review of the literature].
    Rev Chil Pediatr 2015 Mar-Apr;86(2):121-5
    Residente de Dermatología, P. Universidad Católica de Chile.
    Introduction: Pityriasis lichenoides is a benign inflammatory disease of unknown etiology. There are two types of this condition: an acute form (PLEVA = pityriasis lichenoides et varioliformis acuta) and a chronic one (PLC = pityriasis lichenoid chronica). Both are more common in children and young adults. Read More

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