1,142 results match your criteria Parapsoriasis


Dermatological manifestations in patients with human T-cell lymphotropic virus at a reference service in Amazon.

Int J Dermatol 2019 Mar 19. Epub 2019 Mar 19.

Research Laboratory on Skin diseases of Sanitary Interest, Center of Biological and Health Sciences, State University of Pará, Belém, Pará, Brazil.

Introduction: Individuals infected with the human T-cell lymphotropic virus type 1 (HTLV-1) commonly present skin lesions, which may be a warning sign for the diagnosis of infection. This study describes the most prevalent skin manifestations in HTLV carriers attended at the clinic of Núcleo de Medicina Tropical (NMT) of the Universidade Federal do Pará (UFPA) in Belém, Pará, Brazil.

Methods: This is a study of a series of cases of patients infected with human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) treated at NMT UFPA between 1999 and 2016. Read More

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http://dx.doi.org/10.1111/ijd.14422DOI Listing
March 2019
2 Reads

[Current possibilities of the differential diagnosis of plaque parapsoriasis and the early stages of mycosis fungoides].

Arkh Patol 2019;81(1):9-17

Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia, Saint Petersburg, Russia.

Mycosis fungoides (MF) is the most common primary cutaneous epidermotropic T-cell lymphoma (80%). The accurate diagnosis of MF confirmed only by clinical, histological and immunohistochemical signs amounts to 50-75%.

Objective: To investigate genetic markers (FOXP3, STAT4, IL-12B) for the early diagnosis of MF, to estimate the informative value of used diagnostic techniques (histology, immunophenotyping), and to determine clonality by the T-cell receptor γ-chain genes. Read More

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http://dx.doi.org/10.17116/patol2019810119DOI Listing
January 2019
3 Reads

CD30-Positive Angioinvasive Lymphomatoid Papulosis (Type E) Developing from Parapsoriasis en Plaque.

Case Rep Oncol 2018 Sep-Dec;11(3):850-854. Epub 2018 Dec 13.

Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Angioinvasive lymphomatoid papulosis (LyP) type E is a rare variant characterized by angiocentric and angiodestructive features with CD30+ CD8+ lymphocyte infiltration. In rare cases, LyP type E is concomitant with mycosis fungoides, but there is no English report that describe LyP type E developing from parapsoriasis en plaque. In this report, we described a case of angioinvasive LyP (type E) developing from parapsoriasis en plaque, in which we employed immunohistochemical staining for the investigation of its pathomechanisms. Read More

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http://dx.doi.org/10.1159/000495689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341360PMC
December 2018
2 Reads

[Discrasia linfoide epiteliotrópica de células T. Tratamiento con radiación ultravioleta].

Gac Med Mex 2018 ;154(Supp 2):S41-S49

Unidad de Fototerapia. Hospital General Dr. Manuel Gea González, Ciudad de México, México.

Introduction: T-cell lymphoid dyscrasia is a group of different, infrequent, epitheliotropic inflammatory dermatosis that precede cutaneous T-cell lymphomas. Treatment with ultraviolet radiation is safe and efficacious.

Objective: To describe responses to treatment, secondary effects and complications. Read More

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http://dx.doi.org/10.24875/GMM.18004577DOI Listing
January 2018
2 Reads

Risk of venous thromboembolism in patients with mycosis fungoides and parapsoriasis: A Danish nationwide population-based cohort study.

Authors:
Eden Lake

J Am Acad Dermatol 2018 Dec 3. Epub 2018 Dec 3.

Loyola Univ Medical Center Dermatology, 321 N La Grange Rd, La Grange Park, IL. Electronic address:

•Active cancers and inflammation increase the risk for venous thromboembolism. It is unknown whether this applies to mycosis fungoides and parapsoriasis.•Patients with mycosis fungoides and parapsoriasis have increased risk for venous thromboembolism. Read More

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http://dx.doi.org/10.1016/j.jaad.2018.10.073DOI Listing
December 2018
17 Reads

Visual Diagnosis: Severe Ulceronecrotic Eruption with Systemic Symptoms.

Pediatr Rev 2018 Nov;39(11):e54-e56

Division of Dermatology, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH.

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http://dx.doi.org/10.1542/pir.2017-0039DOI Listing
November 2018
2 Reads

Efficacy of phototherapy in pityriasis lichenoides chronica of dark skin: A retrospective study from a tertiary center in Mexico.

Dermatol Ther 2018 11 3;31(6):e12734. Epub 2018 Oct 3.

Department of Dermatology, Universidad Autónoma de Nuevo León, Hospital Universitario "Dr. José Eleuterio González" y Facultad de Medicina, Monterrey, Nuevo León, Mexico.

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http://dx.doi.org/10.1111/dth.12734DOI Listing
November 2018
8 Reads

Dramatic response to brentuximab vedotin in refractory nontransformed CD30 mycosis fungoides allowing allogeneic stem cell transplant and long-term complete remission.

Br J Dermatol 2018 Sep 30. Epub 2018 Sep 30.

Department of Dermatology, AP-HP Hôpital Saint-Louis, Paris, France.

The erythrodermic ulcerated form of mycosis fungoides (MF) is exceptional, and treatment of refractory cases is challenging. Brentuximab vedotin (BV) is a monoclonal antibody combined with monomethyl auristatin E, recently approved for the treatment of refractory CD30 cutaneous T-cell lymphoma. We report a case of refractory MF in a 56-year-old man with a long history of large-plaque parapsoriasis, as revealed by psoriasiform erythroderma, treated initially with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) polychemotherapy, inducing a 2-year complete response. Read More

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http://dx.doi.org/10.1111/bjd.17254DOI Listing
September 2018
9 Reads

Frequency of occurrence of polymorphic light eruption in patients treated with photohardening and patients treated with phototherapy for other diseases.

Photodermatol Photoimmunol Photomed 2019 Mar 13;35(2):100-105. Epub 2018 Nov 13.

Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Graz, Austria.

Background: Medical phototherapy can lead to the manifestation of polymorphic light eruption (PLE), though little is known about the frequency of such events.

Aims: The aim of this Austrian single center study was to retrospectively investigate over a 4-year time period the frequency of PLE in patients prone to the condition and patients with other diseases under phototherapy (mainly narrow-band and broad-band UVB).

Materials And Methods: The data for analysis were obtained from the electronic health and patient record database and patient files of the Photodermatology Unit, Department of Dermatology, Medical University of Graz, Austria. Read More

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http://dx.doi.org/10.1111/phpp.12429DOI Listing
March 2019
6 Reads

Acquired disorders with hypopigmentation: A clinical approach to diagnosis and treatment.

J Am Acad Dermatol 2019 May 17;80(5):1233-1250.e10. Epub 2018 Sep 17.

Department of Dermatology, University of Florida, Gainesville, Florida; Department of Pediatrics, University of Florida, Gainesville, Florida.

Acquired hypopigmented skin changes are commonly encountered by dermatologists. Although hypopigmentation is often asymptomatic and benign, occasional serious and disabling conditions present with cutaneous hypopigmentation. A thorough history and physical examination, centered on disease distribution and morphologic findings, can aid in delineating the causes of acquired hypopigmented disorders. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183250
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http://dx.doi.org/10.1016/j.jaad.2018.07.070DOI Listing
May 2019
19 Reads

A case of pityriasis lichenoides: Rapid resolution with azithromycin monotherapy in 3 weeks.

Dermatol Ther 2018 09 22;31(5):e12681. Epub 2018 Aug 22.

Department of Pathology, School of Medicine, Gaziosmanpasa University, Tokat, Turkey.

Pityriasis lichenoides (PL) is a spectrum of inflammatory skin diseases which include PL et varioliformis acuta (PLEVA) and PL chronica (PLC) as two ends of the disease and rarely both entities can coexist on the same patient. Treatment options are based on case series-reports, and anecdotes, and include topical corticosteroids, topical immunomodulators, systemic antibiotics (tetracycline, erythromycin), and phototherapy. Herein, we report a 13-year-old boy, exhibiting mixed manifestations of PLEVA and PLC lesions concurrently, with a rapid and dramatic response to azithromycin monotherapy. Read More

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http://dx.doi.org/10.1111/dth.12681DOI Listing
September 2018
6 Reads

Frequent relapses in a child with nephrotic syndrome due to PLEVA.

Trop Doct 2018 Oct 12;48(4):348-349. Epub 2018 Aug 12.

4 Professor, Department of Pediatrics, Lady Hardinge Medical College and associated Kalawati Saran Children Hospital, New Delhi, India.

A seven-year-old boy with nephrotic syndrome presented with a frequent rash along with relapse of nephrotic syndrome. Clinical and histological features were suggestive of pityriasis lichenoides et varioliformis acuta (PLEVA). Treatment of the condition with doxycycline led to the cure of the lesions as well as the relapses. Read More

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http://dx.doi.org/10.1177/0049475518788478DOI Listing
October 2018
14 Reads

Chlamydiales Bacterial Sequences in Lesional and Healthy Skin of Patients with Parapsoriasis.

Acta Derm Venereol 2018 Oct;98(9):898-899

Department of Virology, University of Helsinki, P.O. Box 21, FIN-00014 Helsinki, Finland.

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http://dx.doi.org/10.2340/00015555-2999DOI Listing
October 2018
4 Reads

A young man with necrotic skin lesions.

Clin Exp Dermatol 2019 01 26;44(1):102-105. Epub 2018 Jun 26.

Division of Dermatology, Department of Medicine, Phramongkutklao Hospital, Bangkok, Thailand.

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http://dx.doi.org/10.1111/ced.13658DOI Listing
January 2019
1 Read

Comment on: "Dermoscopy of Biett's sign and differential diagnosis with annular maculopapular rashes with scaling".

Indian J Dermatol Venereol Leprol 2018 Jul-Aug;84(4):441-442

Escola de Saúde Pública do Estado do Rio Grande do Sul, Ambulatório de Dermatologia Sanitária, Porto Alegre - RS, Brazil.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_97_18DOI Listing
November 2018

[Pityriasis lichenoides: not always a clear-cut diagnosis!]

Pan Afr Med J 2018 12;29:25. Epub 2018 Jan 12.

Centre d'Anatomopathologie Hassane, Rabat, Maroc.

Pityriasis lichenoides is a rare inflammatory dermatosis occurring in young subjects. It evolves into rashes on the trunk and the limbs which regress spontaneously. We here report a particular case of pityriasis lichenoides whose diagnosis was adjusted due to the scar appearance of the lesions. Read More

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http://dx.doi.org/10.11604/pamj.2018.29.25.10558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987147PMC
June 2018
3 Reads

Authors' reply.

Indian J Dermatol Venereol Leprol 2018 Jul-Aug;84(4):442-443

Department of Medical, Surgical and Neurosciences, Division of Dermatology, University of Siena, Siena, Italy.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_305_18DOI Listing
November 2018

Varicella zoster virus as a possible trigger for the development of pityriasis lichenoides et varioliformis acuta: retrospective analysis of our institutional cases.

Clin Exp Dermatol 2018 Aug 23;43(6):703-707. Epub 2018 May 23.

Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan.

Although numerous infective agents, including varicella zoster virus (VZV), have been described in association with pityriasis lichenoides et varioliformis acuta (PLEVA) and pityriasis lichenoides chronica (PLC), none has been identified consistently in these lesions. We sought to immunohistochemically identify VZV glycoprotein (g)E antigens in the vascular endothelium in PLEVA and PLC lesions, based on our previous observation that gE was detected in the vascular endothelium and eccrine unit up until 2 months and 2.5, respectively, years after herpes zoster (HZ) infection. Read More

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http://dx.doi.org/10.1111/ced.13549DOI Listing
August 2018
2 Reads

Positive effects of hydrogen-water bathing in patients of psoriasis and parapsoriasis en plaques.

Sci Rep 2018 May 23;8(1):8051. Epub 2018 May 23.

Department of Dermatology, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Rd., Jing'an District, Shanghai, China.

Psoriasis and parapsoriasis en plaques are chronic inflammatory skin diseases, both representing therapeutic challenge in daily practice and adversely affecting the quality of life. Reactive oxygen species (ROS) has been evidenced to be involved in the pathogenesis of the chronic inflammatory diseases. We now report that hydrogen water, an effective ROS scavenger, has significant and rapid improvement in disease severity and quality of life for patients with psoriasis and parapsoriasis en plaques. Read More

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http://dx.doi.org/10.1038/s41598-018-26388-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966409PMC
May 2018
5 Reads

Pityriasis lichenoides-like drug reaction: A clinical histopathologic study of 10 cases.

Dermatol Online J 2017 Nov 15;23(11). Epub 2017 Nov 15.

Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York.

Background: Lymphomatoid drug reactions can mimic endogenous T and B cell lymphoproliferative diseases.

Objectives: We present a novel form of cutaneous drug reaction with features of pityriasis lichenoides (PL), a recognized form of T cell dyscrasia.

Methods: Ten cases were studied where a cutaneous eruption exhibiting semblance to PL within a few weeks to months after starting a particular drug. Read More

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November 2017
4 Reads

Branch Duct-type Intraductal Papillary Mucinous Neoplasm Presenting as Paraneoplastic Small Plaque Para-psoriasis.

Indian Dermatol Online J 2018 Jan-Feb;9(1):40-43

Department of Pathology, VPS Lakeshore Hospital, Cochin, Kerala, India.

To present and discuss a novel association between branch duct-type intraductal papillary mucinous neoplasm and paraneoplastic parapsoriasis. We present the case of a middle-aged male presenting with skin lesions that were suggestive of parapsoriasis, resistant to treatment, and in whom a diagnosis of branch-type intraductal papillary mucinous neoplasm of the pancreas was eventually made. A curative Whipple's surgery led to complete resolution of the skin lesions within 3 weeks. Read More

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http://dx.doi.org/10.4103/idoj.IDOJ_427_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803941PMC
February 2018
3 Reads

Blisters Induced by PUVA: A Report of 5 Cases.

Actas Dermosifiliogr 2018 Oct;109(8):e11-e16

Servicio de Dermatología, Hospital Universitario de Cabueñes, Gijón, Asturias, España.

Blisters associated with PUVA treatments are an adverse effect of photochemotherapy that has been reported in the literature. Asymptomatic blisters appear spontaneously mainly on the lower limbs and resolve without treatment. The differential diagnoses to consider include a phototoxic reaction, pseudoporphyria, and PUVA-induced bullous pemphigoid. Read More

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http://dx.doi.org/10.1016/j.ad.2017.10.011DOI Listing
October 2018
2 Reads

Possible role of plasmacytoid dendritic cells in pityriasis lichenoides.

Clin Exp Dermatol 2018 Jun 19;43(4):404-409. Epub 2018 Jan 19.

Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.

Background: Plasmacytoid dendritic cells (pDCs) and their product, type I interferons (IFNs), have been implicated in the pathogenesis of several skin disorders characterized by an interface dermatitis (ID) pattern, such as lichen planus (LP). A type I IFN signature has previously been documented in pityriasis lichenoides (PL). Although pDCs are known to be the main source and most potent producers of local type I IFNs, their role in PL has not been investigated. Read More

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http://dx.doi.org/10.1111/ced.13351DOI Listing
June 2018
3 Reads

Pityriasis lichenoides: Long-term follow-up study.

Pediatr Dermatol 2018 Mar 9;35(2):213-219. Epub 2018 Jan 9.

Department of Dermatology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Background/objectives: Pityriasis lichenoides is an uncommon papulosquamous disorder of unknown etiology. The objective of this study was to review the clinical features and treatment responses of individuals with pityriasis lichenoides seen at a tertiary referral center.

Methods: Seventy-five patients diagnosed with pityriasis lichenoides between 1997 and 2013 were reviewed, and 46 had long-term follow-up via telephone interviews. Read More

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http://dx.doi.org/10.1111/pde.13396DOI Listing
March 2018
12 Reads

Skin and coeliac disease, a lot to think about: a case series.

BMJ Case Rep 2018 Jan 4;2018. Epub 2018 Jan 4.

Pediatric Department, Hospital of Divino Espírito Santo of Ponta Delgada, Ponta Delgada - São Miguel, Azores, Portugal.

Coeliac disease (CD) is an autoimmune disease, characterised by a permanent sensitivity to gluten. It is being progressively recognised as a multisystemic disease, with multiple extraintestinal manifestations. Skin conditions (eg, dermatitis herpetiformis) are an example of its manifestations; however, its underlying mechanisms are still not well understood. Read More

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http://dx.doi.org/10.1136/bcr-2017-222797DOI Listing
January 2018
9 Reads

Pitiryasis Lichenoides et Varioliformis Aacuta Associated With Human Herpesvirus 7.

Actas Dermosifiliogr 2018 Sep 6;109(7):e6-e10. Epub 2017 Dec 6.

Unidad de Dermatología y Venereología, Centro Hospitalario São João, EPE, Oporto, Portugal.

Pityriasis lichenoides et varioliformis acuta and pityriasis lichenoides chronica represent 2 ends of a disease spectrum of unknown etiology. Herein we describe 2 cases of pityriasis lichenoides et varioliformis acuta, in which human herpesvirus 7 DNA was detected in skin samples by polymerase chain reaction methodology, an association not previously described. This report may support the involvement of viral infection in the etiopathogeny of this disease. Read More

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http://dx.doi.org/10.1016/j.ad.2017.03.023DOI Listing
September 2018
5 Reads

Relationship Between Pityriasis Lichenoides and Mycosis Fungoides: A Clinicopathological, Immunohistochemical, and Molecular Study.

Am J Dermatopathol 2018 Jun;40(6):409-415

Departments of Dermatology.

Background: Several cases of pityriasis lichenoides (PL) have been reported to evolve into mycosis fungoides (MF).

Objective: To elucidate clues to this progression.

Methods: Fifty-eight patients with PL between 2000 and 2013 (follow-up: 3-16 years, average: 8. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001057DOI Listing
June 2018
13 Reads

Risk of venous thromboembolism in patients with mycosis fungoides and parapsoriasis: A Danish nationwide population-based cohort study.

J Am Acad Dermatol 2018 Jun 1;78(6):1077-1083.e4. Epub 2017 Dec 1.

Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.

Background: Mycosis fungoides (MF) and parapsoriasis are characterized by malignant proliferation and chronic inflammation, which may affect the risk for venous thromboembolism (VTE).

Objectives: To examine the risk for VTE in patients with MF and parapsoriasis.

Methods: We conducted a nationwide population-based cohort study in Denmark to examine the relative risk (RR) of VTE in 525 patients with MF and 634 patients with parapsoriasis compared with that in sex- and age-matched controls from the general population. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622173274
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http://dx.doi.org/10.1016/j.jaad.2017.11.043DOI Listing
June 2018
9 Reads

Severe Mucha-Habermann-Like Ulceronecrotic Skin Disease in T-Cell Acute Lymphoblastic Leukemia Responsive to Basiliximab and Stem Cell Transplant.

Pediatr Dermatol 2017 Sep;34(5):e265-e270

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

A 5-year-old girl with T-cell acute lymphoblastic leukemia (T-ALL) developed a progressive eruption of crusted papules and ulcerative plaques involving 80% of her body surface area with histopathology consistent with febrile ulceronecrotic Mucha-Habermann disease (FUMHD), although multiple specimens also contained clonal leukemic cells. Her skin disease was refractory to many classic treatments for FUMHD, including methotrexate, and became so severe that concern about superinfection prevented intensification of chemotherapy for her malignancy. The addition of basiliximab promoted gradual improvement of the skin, allowing for chemotherapy intensification and subsequent bone marrow transplantation, after which the eruption resolved completely. Read More

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http://doi.wiley.com/10.1111/pde.13235
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http://dx.doi.org/10.1111/pde.13235DOI Listing
September 2017
40 Reads

Defining the mimics and clinico-histological diagnosis criteria for mycosis fungoides to minimize misdiagnosis.

Int J Womens Dermatol 2017 Jun 30;3(2):100-106. Epub 2017 Jan 30.

Department of Dermatology, Faculty of Medicine, Hospital Hassan II, Fez, Morocco.

Background: Mycosis fungoides (MF) is a significant diagnostic challenge; it has various differential diagnosis especially at an early stage. Our aim was to describe mimics of MF clinically and histologically, and to define significant diagnostic criteria of the disease.

Methods: This was a retro-prospective cohort of 370 patients in whom the diagnosis of MF was suspected clinically. Read More

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http://dx.doi.org/10.1016/j.ijwd.2016.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440453PMC
June 2017
13 Reads

Pityriasis Lichenoides et Varioliformis Acuta and Psoriasis Vulgaris: Mere Coincidence or a Rare Association?

Chin Med J (Engl) 2017 02;130(4):501-502

Department of Dermatology, Peking Union Medical College Hospital, Beijing 100730, China.

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http://dx.doi.org/10.4103/0366-6999.199837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324393PMC
February 2017
27 Reads

Skin Microbiome in Small- and Large-plaque Parapsoriasis.

Acta Derm Venereol 2017 Jun;97(6):685-691

Department of Dermatology and Allergology, University of Helsinki, and Helinki University Hospital, FIN-00250 Helsinki, Finland.

Staphylococcal enterotoxins have been shown to promote lymphoma-associated immune dysregulation. This study examined changes in the skin microbiome of parapsoriasis compared with intact skin. Swab microbiome specimens were taken of the parapsoriasis lesions of 13 patients. Read More

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http://dx.doi.org/10.2340/00015555-2631DOI Listing
June 2017
5 Reads

Use of Phototherapy in Children.

Pediatr Dermatol 2017 Mar 30;34(2):150-155. Epub 2017 Jan 30.

Department of Dermatology, Alder Hey Children's Hospital, Liverpool, UK.

Background: Phototherapy is a well-recognized treatment in adults and children. Previous articles have reported success in treating recalcitrant skin disorders such as atopic dermatitis (AD), psoriasis, pityriasis lichenoides chronica, and vitiligo in children.

Methods: This was a retrospective review over an 18-month period from June 2012 to December 2013 of all children receiving phototherapy in a tertiary pediatric dermatology center. Read More

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http://doi.wiley.com/10.1111/pde.13072
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http://dx.doi.org/10.1111/pde.13072DOI Listing
March 2017
19 Reads

Treatment of adult diffuse pityriasis lichenoides chronica with narrowband ultraviolet B: experience and literature review.

Clin Exp Dermatol 2017 Apr 23;42(3):303-305. Epub 2017 Jan 23.

Dermatology Department, Hospital Universitario Sanitas La Zarzuela, Universidad Francisco de Vitoria, Madrid, Spain.

Pityriasis lichenoides chronica (PLC) is an infrequent dermatosis of unknown aetiology, wholse evolution and response to treatment differs between children and adults. When PLC is recalcitrant or unresponsive to topical treatment, phototherapy is one of the main treatments used. We carried out a prospective study of adult diffuse PLC treated with narrowband ultraviolet B (NB-UVB). Read More

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http://dx.doi.org/10.1111/ced.13035DOI Listing
April 2017
4 Reads

[Febrile ulceronecrotic Mucha-Habermann disease].

Rev Med Chil 2016 Sep;144(9):1214-1217

Anatomía Patológica, Hospital Clínico San Borja Arriarán, Universidad de Chile, Santiago, Chile.

Pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC) and febrile ulceronecrotic Mucha-Habermann disease (FUMHD) are considered different manifestations of the same disease. Febrile ulceronecrotic Mucha-Habermann disease is a rare, and potentially lethal illness which is characterized by fast progression of numerous papules that converge, ulcerate and form a plaque with a necrotic center, together with hemorrhagic vesicles and pustules that are associated with high fever and variable systemic symptoms. We report a 16 years old male presenting with erythematous papules with crusts and fever. Read More

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http://dx.doi.org/10.4067/S0034-98872016000900017DOI Listing
September 2016
20 Reads

Dermoscopy of Biett's sign and differential diagnosis with annular maculo-papular rashes with scaling.

Indian J Dermatol Venereol Leprol 2017 Mar-Apr;83(2):270-273

Department of Dermatology, Division of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.

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http://dx.doi.org/10.4103/0378-6323.196318DOI Listing
June 2017
13 Reads

Past, present and future of cutaneous lymphomas.

Authors:
Lorenzo Cerroni

Semin Diagn Pathol 2017 Jan 28;34(1):3-14. Epub 2016 Nov 28.

Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, 8036 Graz, Austria. Electronic address:

Primary cutaneous lymphomas represent a broad group of diseases with different clinical, histopathological, phenotypic, molecular, and prognostic features. All cutaneous lymphomas share the same tropism of neoplastic lymphocytes for the skin, but precise classification is paramount for proper management of the patients. Primary cutaneous lymphomas are classified according to the schemes proposed by the European Organization for Research and Treatment of Cancer (EORTC)-Cutaneous Lymphomas Task Force together with the World Health Organization (WHO) in 2005, and the WHO classification of 2008 with the 2016 update. Read More

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http://dx.doi.org/10.1053/j.semdp.2016.11.001DOI Listing
January 2017
22 Reads

Phototherapy in children: Considerations and indications.

Clin Dermatol 2016 Sep-Oct;34(5):633-9. Epub 2016 May 24.

Harvard Medical School, Dermatology Program, Division of Allergy and Immunology, Department of Medicine, Boston Children's Hospital, Boston, MA. Electronic address:

Phototherapy can be a safe and effective treatment for various skin diseases in children. Special considerations governing the use of this treatment modality in pediatric populations include patient, family, and facility-based factors that are oriented around heightened concerns with regard to safety and tolerability of treatment. Although phototherapy has been found to be effective in a wide range of dermatologic conditions affecting pediatric populations, including psoriasis, atopic dermatitis, pityriasis lichenoides, cutaneous T-cell lymphoma, and vitiligo, there is need for additional research on other conditions in which phototherapy has shown promise. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2016.05.018DOI Listing
May 2017
13 Reads

Successful treatment of pityriasis lichenoides chronica with narrow-band ultraviolet B therapy in a patient with Keratitis-Ichthyosis-Deafness syndrome: a case report.

Dermatol Online J 2016 May 15;22(5). Epub 2016 May 15.

Marmara University, School of Medicine, Department of Dermatology, Istanbul.

Keratitis-ichthyosis-deafness (KID) syndrome is a rare genodermatosis causing ichthyosis-like skin lesions, keratitis, and deafness. Herein, we report a patient with this rare syndrome in association with pityriasis lichenoides chronica, which was succesfully treated with narrow-band ultraviolet B phototherapy despite our concerns regarding the increased risk of squamous cell carcinoma, hyperpyrexia, and keratitis. Read More

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May 2016
19 Reads

Young Male With Painful Skin Necrosis.

Authors:
Ze-Hu Liu Hong Shen

Ann Emerg Med 2016 Sep;68(3):276-311

Department of Dermatology, Affiliated Third Hospital of Hangzhou, Anhui Medical University, Hangzhou, China.

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http://dx.doi.org/10.1016/j.annemergmed.2016.02.007DOI Listing
September 2016
7 Reads

Granulomatous slack skin - seven years follow-up of a case with features of "parapsoriasis en plaques", muscle involvement, granulomatous vasculitis, and necrobiotic changes.

Rom J Morphol Embryol 2016 ;57(2):539-46

Department of Dermatology, "Carol Davila" Central University Emergency Military Hospital, Bucharest, Romania;

Granulomatous slack skin (GSS) represents an extremely rare variant of mycosis fungoides with only 70 cases reported in the literature to date. It is characterized clinically by the occurrence of bulky, pendulous skinfolds, usually located in flexural areas and histologically by an infiltrate composed of small neoplastic T-lymphocytes joined by granulomatous inflammation with scattered multinucleated giant cells containing nuclei arranged in a wreath-like fashion. Since its first description, very rare cases of GSS with muscle involvement, large vessels involvement, or necrobiotic changes have been reported. Read More

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April 2017
4 Reads

Phototherapy for Pityriasis Lichenoides in the Pediatric Population: A Review of the Published Literature.

Am J Clin Dermatol 2016 Dec;17(6):583-591

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., Miami, FL, 33136, USA.

Background: Pityriasis lichenoides (PL) is a dermatologic disorder that manifests in either the acute (pityriasis lichenoides et varioliformis acuta) or the chronic form (pityriasis lichenoides chronica, also known as parapsoriasis chronica). Traditional first-line therapy consists of corticosteroids or antibiotics; however, these treatments are often accompanied with multiple side effects and may be ineffective.

Objective: The goal of this study was to review the use of phototherapy for treating PL in the pediatric population. Read More

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http://dx.doi.org/10.1007/s40257-016-0216-2DOI Listing
December 2016
23 Reads

Febrile ulceronecrotic Mucha-Habermann disease in an 8-year-old boy responding to methotrexate.

Int J Dermatol 2016 Nov;55(11):1205-1209

ExpressMed Laboratories, Kingdom of Bahrain.

Background: Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare fulminant variant of pityriasis lichenoides et varioliformis acuta (PLEVA) characterized by a rapidly progressive course with predominant ulceronecrotic lesions associated with fever and systemic manifestations. First described by Degos in 1966, it carries a high morbidity and is potentially fatal. The exact pathogenesis is not clear, but it is proposed to be the result of hypersensitivity reaction to an infection. Read More

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http://dx.doi.org/10.1111/ijd.13323DOI Listing
November 2016
12 Reads

Seronegative arthritis secondary to Mucha-Habermann disease.

Med Clin (Barc) 2016 Dec 24;147(12):564. Epub 2016 Jun 24.

Servicio de Reumatología, Hospital Universitario San Cecilio, Granada, España.

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http://dx.doi.org/10.1016/j.medcli.2016.05.002DOI Listing
December 2016
6 Reads

TOX expression and role in CTCL.

J Eur Acad Dermatol Venereol 2016 Sep 26;30(9):1497-502. Epub 2016 Jun 26.

Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.

Background: Cutaneous T-cell lymphomas (CTCL) are skin malignancies including mycosis fungoides (MF) and CD30(+) lymphoproliferative disorders (LPD). In early disease, CTCL can be difficult to diagnose, especially in MF for which there is no reliable diagnostic marker. MF/CTCL have increased expression of thymocyte selection-associated HMG box protein (TOX). Read More

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http://dx.doi.org/10.1111/jdv.13651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992428PMC
September 2016
2 Reads

Pityriasis Lichenoides et Varioliformis Acuta: Remission with Hypopigmentation.

J Pediatr 2016 Sep 11;176:211-211.e1. Epub 2016 Jun 11.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.jpeds.2016.05.057DOI Listing
September 2016
11 Reads

Pityriasis lichenoides chronica presenting with bilateral palmoplantar involvement.

Cutis 2016 May;97(5):345;347;358

Bay Dermatology/Largo Medical Center, Florida, USA.

Pityriasis lichenoides is an uncommon, acquired, idiopathic, self-limiting skin disease that poses a challenge to patients and clinicians to diagnose and treat. Several variants exist including pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC), and febrile ulcer-onecrotic Mucha-Habermann disease. Precise classification can be difficult due to an overlap of clinical and histologic features. Read More

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May 2016
10 Reads

Pityriasis lichenoides chronica responds to minocycline in three patients.

Int J Dermatol 2016 Sep 3;55(9):1027-9. Epub 2016 Jun 3.

Department of Dermatology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia.

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http://doi.wiley.com/10.1111/j.1365-4632.2010.04659.x
Publisher Site
http://dx.doi.org/10.1111/j.1365-4632.2010.04659.xDOI Listing
September 2016
6 Reads

Paraviral exanthems.

Expert Rev Anti Infect Ther 2016 06;14(6):601-11

c School of Public Health and Primary Care , The Chinese University of Hong Kong and Prince of Wales Hospital , Shatin , Hong Kong.

Introduction: Paraviral exanthems are skin diseases suspected to be caused by viruses, with a single virus-exanthem relationship not universally accepted. Although most paraviral exanthems are self-remitting, accurate diagnoses are important as some patients might develop complications. Some of the differential diagnoses might cause serious complications, and some paraviral exanthems might lead to complications for at-risk groups such as pregnant women. Read More

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http://dx.doi.org/10.1080/14787210.2016.1184084DOI Listing
June 2016
10 Reads

Overlap between maculopapular exanthema and drug reaction with eosinophilia and systemic symptoms among cutaneous adverse drug reactions in a dermatology ward.

Br J Dermatol 2016 Dec 6;175(6):1274-1283. Epub 2016 Sep 6.

Dermatology Department, Coimbra University Hospital Centre, Coimbra, Portugal.

Background: Inpatients with cutaneous adverse drug reactions (CADR) with overlapping features between maculopapular exanthema (MPE) and drug reaction with eosinophilia and systemic symptoms (DRESS) were examined.

Objectives: To characterize patients with exanthema and few systemic symptoms not meeting the criteria for DRESS [overlapping MPE-DRESS (MP/DR)].

Methods: We undertook a comparative analysis of clinical and laboratory features of patients with MPE, MP/DR and DRESS (2008-12). Read More

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http://dx.doi.org/10.1111/bjd.14704DOI Listing
December 2016
8 Reads