1,159 results match your criteria Parapharyngeal Space Tumors


Transoral Excision of Parapharyngeal Tumors.

Ear Nose Throat J 2020 May 19:145561320923171. Epub 2020 May 19.

Department of Otolaryngology-Head and Neck Surgery, Loma Linda University Medical Center, Loma Linda, CA, USA.

Objectives: The transoral approach for parapharyngeal space tumors has been criticized due to its restrictive exposure and increased rate of vascular and nerve injuries. However, for certain tumors-namely those that are prestyloid, benign, and well-encapsulated-the transoral approach reduces overall morbidity while providing direct access. Transoral surgeons can rely on this approach for select tumors seen clearly on intraoral examination in the bulging lateral pharynx. Read More

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http://dx.doi.org/10.1177/0145561320923171DOI Listing

Management of Parapharyngeal Space Tumor Using Transoral Robotic Surgery: The Tonsillar Fossa Battlefield.

J Craniofac Surg 2020 Apr 16. Epub 2020 Apr 16.

Unit of Otolaryngology, University of Foggia, Foggia.

Introduction: The management of parapharyngeal space (PPS) tumors is surgical, but the approach remains a challenge. Attention should be paid to avoid intra-operative bleeding, cranial nerves damage, and external scars.

Presentation Of Case: The authors report a case of a 23-year-old female, with complaint of progressive, painless swelling just below the right angle of the mandible of 6-month's duration. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006453DOI Listing

Bucco-Parapharyngeal Occurrence of Pleomorphic Spindle Cell Lipoma-A Unique Entity: Case Report.

J Clin Pediatr Dent 2020 ;44(2):107-111

Lipomas are common benign neoplasms of oral region which occur scarcely in the parapharyngeal space (PPS). The diversity observed in its histologic presentation classified it into many subtypes among which Spindle Cell Lipoma (SCL) is a rare entity. SCL is an uncommon benign tumor of adipose tissue usually located superficially in the neck, back and shoulder region but its presentation in oral and pharyngeal spaces is very rare. Read More

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http://dx.doi.org/10.17796/1053-4625-44.2.7DOI Listing

Expert Consensus on Procedures and Operations of Navigation-guided Needle Biopsy Techniques for Skull Base Tumours.

Chin J Dent Res 2020 ;23(1):27-32

Skull base surgery is an interdisciplinary subject. The anatomical structures in the skull base related to oral and maxillofacial surgery include the parapharyngeal space, the pterygopalatine fossa and the infratemporal space. This operative area is one of the most challenging surgical areas in oral and maxillofacial surgery due to its deep site, complex anatomy and high risk. Read More

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http://dx.doi.org/10.3290/j.cjdr.a44333DOI Listing

Surgical Approaches to Benign Parapharyngeal Space Tumors-5-Year Experience.

Iran J Otorhinolaryngol 2020 Jan;32(108):43-48

Students' Scientific Research Center, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Introduction: Various surgical approaches to parapharyngeal space (PPS) tumors are introduced to obtain complete removal with the preservation of the surrounding structures in parapharyngealneoplasms. Here, we will discuss the main techniques and their outcome.

Materials And Methods: This retrospective study was conducted on 78 patients undergone either transoral, transcervical or a combination of these two approaches for the resection of PSS tumors from January 2010 to January 2015. Read More

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http://dx.doi.org/10.22038/ijorl.2019.38350.2268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007997PMC
January 2020

Trans-oral robotic surgery in the management of parapharyngeal space tumors: A systematic review.

Oral Oncol 2020 Apr 12;103:104581. Epub 2020 Feb 12.

Humanitas University, Via Rita Levi Montalcini, 4, 20090 Pieve Emanuele (MI), Italy; Department of Otorhinolaryngology Head and Neck Surgery, IRCCS Humanitas Clinical and Research Center, Via Alessandro Manzoni, 56, 20089 Rozzano (MI), Italy.

Purpose: To perform a systematic review of studies evaluating Trans-oral Robotic Surgery (TORS) in the treatment of parapharyngeal space (PPS) tumors.

Methods: A comprehensive electronic search was performed in PubMed/MEDLINE, Cochrane Library, and Google Scholar databases for appropriate published studies. The last search was conducted on November 9, 2019. Read More

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http://dx.doi.org/10.1016/j.oraloncology.2020.104581DOI Listing

Infratemporal fossa surgical approaches to primary/recurrent malignancies of salivary origin: paradigm surgical shift, patient selection, and oncologic outcomes.

Curr Opin Otolaryngol Head Neck Surg 2020 Apr;28(2):79-89

Department Otorhinolaryngology, Head and Neck Surgery, Nottingham University Hospitals, Queens Medical Centre Campus, Nottingham, UK.

Purpose Of Review: To review, the surgical approaches available on diagnosing a patient with salivary gland malignancy in the infratemporal fossa (ITF). To comment on patient evaluation and method of treatment selection. To identify and report on patient outcome data and make recommendations on future needs. Read More

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http://dx.doi.org/10.1097/MOO.0000000000000613DOI Listing

Transoral robotic narrow field oropharyngectomy for tumours of the parapharyngeal space.

Int J Med Robot 2020 Jun 5;16(3):e2083. Epub 2020 Mar 5.

Department of Otolaryngology-Head and Neck Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

The advent of transoral robotic surgery (TORS) has allowed transoral approaches for parapharyngeal space (PPS) tumours to be re-evaluated. It provides enhanced visualisation and instrument access for appropriate tumours. We describe a specific technique, TORS narrow-field oropharyngectomy, that is ideal for benign PPS tumours which have been violated by intra-oral biopsy or incision and drainage. Read More

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http://dx.doi.org/10.1002/rcs.2083DOI Listing

Transcervical endoscopic approach for parapharyngeal space: a cadaver study and clinical practice.

Acta Otolaryngol 2020 Feb 14;140(2):163-169. Epub 2020 Jan 14.

Department of Otorhinolaryngology-Head and Neck Surgery (Shanghai Key Clinical Disciplines of Otorhinolaryngology), Eye, Ear, Nose, Throat Hospital of Fudan University, Shanghai, China.

The traditional transcervical approach is frequently applied but limited in handling the tumors in parapharyngeal space. We explore a new transcervical endoscopic approach with more direct visualization, less complications, and better outcomes. Eight cadaver heads (sixteen sides) were prepared for endoscopic dissection. Read More

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http://dx.doi.org/10.1080/00016489.2019.1663924DOI Listing
February 2020

[First bite syndrome: clinical study of six cases and review of the literature].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Dec;33(12):1196-1199

Department of Otorhinolaryngology Head and Neck Surgery,the First Affiliated Hospital of Chengdu Medical College,Chengdu,610500,China.

The aim of this study is to explore the etiology, diagnosis and treatment of first bite syndrome(FBS). Clinical data of six patients with FBS were analyzed retrospectively. There were 4 cases of parapharyngeal space tumor resection complicated with FBS, 1 case of parotidectomy of deep lobe parotid gland tumor complicated with FBS, and 1 case of no definite cause. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.12.019DOI Listing
December 2019

Parapharyngeal Hemangiopericytoma: the Role for Mandibular Proximal Segment Replantation-Review of Literature.

Indian J Surg Oncol 2019 Dec 9;10(4):708-712. Epub 2019 Sep 9.

3Dental Research Center, Mashhad University of Medical Sciences, Vakilabad Blvd, Mashhad, Iran.

Pharyngeal hemangiopericytoma is a rare tumor .Surgical access to space has been selected based on the location of the tumor in this space, size, and type of pathology. Hemangiopericytoma requires extracapsular dissection. Read More

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http://dx.doi.org/10.1007/s13193-019-00975-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895317PMC
December 2019

Endoscopic transnasal transmaxillary approach to the upper parapharyngeal space and the skull base.

Eur Arch Otorhinolaryngol 2020 Mar 16;277(3):801-807. Epub 2019 Dec 16.

Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Purpose: Treatment of tumors arising in the upper parapharyngeal space (PPS) or the floor of the middle cranial fossa is challenging. This study aims to present anatomical landmarks for a combined endoscopic transnasal and anterior transmaxillary approach to the upper PPS and the floor of the middle cranial fossa and to further evaluate their clinical application.

Methods: Dissection of the upper PPS using a combined endoscopic endonasal transpterygoid and anterior transmaxillary approach was performed in six cadaveric heads. Read More

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http://dx.doi.org/10.1007/s00405-019-05761-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031166PMC

Parapharyngeal Alveolar Soft Part Sarcoma in a 5-Year-Old Child.

J Craniofac Surg 2020 Jan/Feb;31(1):e99-e101

Department of Internal Medicine, Government Medical College, Srinagar, India.

Alveolar soft part sarcoma (ASPS) is a rare malignancy of head and neck region; orbit and tongue being most common subsites affected by this rare tumor. A 5-year-old female presented with computed tomography scan evidence of right-sided prestyloid parapharyngeal mass. Complete excision was performed through trans-cervical approach. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006050DOI Listing
March 2020
0.676 Impact Factor

Cystic Myoepithelioma of Parapharyngeal Space.

Indian J Otolaryngol Head Neck Surg 2019 Oct 10;71(Suppl 1):689-692. Epub 2018 Sep 10.

Department of ENT, Sundaram Medical Foundation, Dr. Rangarajan Memorial Hospital, Chennai, 600040 India.

Myoepitheliomas are rare tumours of salivary glands arising from myoepithelial cells, which are normal constituent of the salivary acini and ducts and are found between the epithelial cells and the basement membrane. The most common site of origin of Myoepitheliomas are the salivary glands and rarely other sites in the head and neck have been described in literature. Myoepithelioma arising from parapharyngeal space provide both a diagnostic and therapeutic challenge. Read More

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http://dx.doi.org/10.1007/s12070-018-1488-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848441PMC
October 2019

Contemporary Management of Parapharyngeal Tumors.

Curr Oncol Rep 2019 Nov 14;21(11):103. Epub 2019 Nov 14.

Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, 2233 Post St 3rd Floor, San Francisco, CA, 94115, USA.

Purpose Of Review: Management of parapharyngeal tumors is challenging due to the complex anatomic nature of the space and the wide range of pathologies encountered. This article will review the anatomy, common pathologies, and management of parapharyngeal masses. Surgical strategies are also reviewed. Read More

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http://dx.doi.org/10.1007/s11912-019-0853-8DOI Listing
November 2019

The Role of Transoral Robotic Surgery for Parapharyngeal Space: Experience of a Tertiary Center.

J Craniofac Surg 2020 Jan/Feb;31(1):117-120

Department of Otolaryngology-Head and Neck Surgery, European Institute of Oncology IRCCS, Milan.

The parapharyngeal space (PPS) is an anatomically and functionally complex region of the craniofacial district. Tumors that originate from this region are rare, and surgery is currently the best practice in the vast majority of cases with different surgical approaches being reported in the literature. Recently, mini-invasive robotic/endoscopic techniques have begun to emerge as effective alternatives in selected cases. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005912DOI Listing
April 2020
2 Reads

Large Laryngeal Lipoma with Extra Laryngeal Component Mimics Mixed Form Laryngocele: A Case Report.

Adv J Emerg Med 2019 28;3(4):e45. Epub 2019 Jul 28.

Department of General Surgery, Hamadan University of Medical Sciences, Besat Hospital, Hamadan, Iran.

Introduction: Lipomas are the most common benign neoplasms, occurring in any part of the body where fat is present. Their occurrence in the head and neck is not common. Here, we report a large laryngeal lipoma with extra laryngeal component, mimicking mixed form of laryngocele. Read More

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http://dx.doi.org/10.22114/ajem.v0i0.196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789068PMC
July 2019
2 Reads

Otitis Media With Effusion Caused by a Parapharyngeal Tumor Showing Normal Nasopharyngeal Findings.

Ear Nose Throat J 2019 Oct 13:145561319881513. Epub 2019 Oct 13.

Department of Otolaryngology, Juntendo University Nerima Hospital, Tokyo, Japan.

The objective of this study is to evaluate otitis media with effusion (OME) among patients with parapharyngeal tumor. We have experienced 82 parapharyngeal tumor cases and encountered 14 patients complaining of hearing loss due to OME as the initial symptom. These patients showed normal nasopharyngeal findings and the presence of tumor had been detected long time after the beginning of their hearing symptoms (4 months to 13 years: median 2. Read More

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http://dx.doi.org/10.1177/0145561319881513DOI Listing
October 2019
1 Read

A minimally invasive endoscopic transnasal retropterygoid approach to the upper parapharyngeal space: anatomic studies and surgical implications.

Int Forum Allergy Rhinol 2019 11 1;9(11):1263-1272. Epub 2019 Oct 1.

Department of Otolaryngology, Eye, Ear, Nose, and Throat Hospital, Shanghai Medical College of Fudan University, Shanghai, China.

Background: Surgery remains the mainstay of treatment for lesions in the parapharyngeal space. However, gaining access to the parapharyngeal space is often challenging. In this study we aim to describe a minimally invasive technique of approaching the upper parapharyngeal space through an endoscopic transnasal retropterygoid approach, based on anatomic studies and surgeries. Read More

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http://dx.doi.org/10.1002/alr.22437DOI Listing
November 2019
1 Read

Is Regional Lymph Node Metastasis of Head and Neck Paraganglioma a Sign of Aggressive Clinical Behavior: A Clinical/Pathologic Review.

Ear Nose Throat J 2019 Sep 29:145561319863373. Epub 2019 Sep 29.

Department of Pathology, Rush University, Chicago, IL, USA.

Background: Head and neck paraganglioma is a rare neoplasm of the paraganglia. It accounts for <1% of all head and neck tumors. It usually has benign clinical course; however, malignant paraganglioma can only be diagnosed by showing metastatic disease. Read More

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http://dx.doi.org/10.1177/0145561319863373DOI Listing
September 2019
2 Reads
0.881 Impact Factor

Endoscopic transmastoid posterior petrosal approach for locally aggressive tumors in the petrous part of the temporal bone involving the internal auditory canal, jugular foramen, and hypoglossal canal.

J Neurosurg 2019 Sep 27:1-13. Epub 2019 Sep 27.

Departments of1Neurosurgery and.

Objective: The posterior petrosal approach is an established surgical method offering wide access to skull base lesions through mastoid air cells. The authors describe their experience with the endoscopic transmastoid "posterior petrosal" approach (EPPAP) for skull base tumors involving the internal auditory canal (IAC), jugular foramen, and hypoglossal canal.

Methods: The EPPAP was performed for 7 tumors (3 chordomas, 2 chondrosarcomas, 1 schwannoma, and 1 solitary fibrous tumor). Read More

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http://dx.doi.org/10.3171/2019.5.JNS19187DOI Listing
September 2019
2 Reads

Anterolateral Approach for Retrostyloid Superior Parapharyngeal Space Schwannomas Involving the Jugular Foramen Area: A 20-Year Experience.

World Neurosurg 2019 Dec 11;132:e40-e52. Epub 2019 Sep 11.

Neurosurgery Unit, Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy; Neurosurgery Unit, Department of Surgical Sciences, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Background: Schwannomas encompassing the superior parapharyngeal space are challenging lesions because of the anatomical complexity of this region and the frequent involvement of the neurovascular structures of the jugular foramen. The purpose of this study is to report the technical aspects and the advantages of the anterolateral approach, here proposed for schwannomas of this complex area.

Methods: The main steps of the anterolateral approach are described in detail, along with the results of a consecutive series of 38 patients with a retrostyloid superior parapharyngeal schwannoma involving the jugular foramen operated on by means of this route between 1999 and 2019. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.09.006DOI Listing
December 2019
3 Reads

Clinical classification of clival chordomas for transnasal approaches.

Neurosurg Rev 2019 Aug 8. Epub 2019 Aug 8.

Department of Neurosurgery, The First Affiliated Hospital of China Medical University, No. 155, North Nanjing Street, Heping District, Shenyang, 110001, Liaoning, People's Republic of China.

Endoscopic endonasal approaches (EEAs) are ideal for most chordomas, but there is little information regarding the practical clinical classification of clival chordomas to guide surgery with EEAs. This article investigates a relatively concise and practical clinical classification system for clival chordomas and summarizes the clinical characteristics and operative key points of different clinical types. Here, 55 patients with clival chordomas treated through EEAs from 2012 to 2017 were retrospectively reviewed. Read More

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http://dx.doi.org/10.1007/s10143-019-01153-wDOI Listing
August 2019
5 Reads

Parapharyngeal space tumors: a serial case study.

J Int Med Res 2019 Aug 29;47(8):4004-4013. Epub 2019 Jul 29.

1 Department of Otolaryngology & Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan.

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http://dx.doi.org/10.1177/0300060519862659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726805PMC

Surgical management of extracranial nerve sheath tumours in a tertiary care center.

World J Otorhinolaryngol Head Neck Surg 2019 Jun 16;5(2):76-81. Epub 2019 Mar 16.

Department of ENT and Head Neck Surgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, 751019, India.

Objective: Excision of the nerve sheath tumours of head and neck is always a challenge to the surgeon because of their close proximity of the neurovascular structures.

Methods: It is a retrospective study contained 13 consecutive patients of nerve sheath tumours involving the head and neck from March 2013 to February 2017 in the department of Otorhinolaryngology and Head Neck Surgery in a tertiary care referral hospital. The retrospective clinical data, diagnostic procedures, surgical approaches and their complications are analyzed after 12 months of surgery. Read More

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http://dx.doi.org/10.1016/j.wjorl.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617236PMC
June 2019
3 Reads

Updated WHO nomenclature of head and neck lesions and associated imaging findings.

Insights Imaging 2019 Jul 16;10(1):72. Epub 2019 Jul 16.

Department of Radiology, Section of Neuroradiology, University of Chicago, 5841 S Maryland Avenue, Chicago, IL, 60637, USA.

This article reviews the imaging features of head and neck lesions with updated 2017 World Health Organization (WHO) nomenclature. The major WHO changes include refined terminology of existing entities, descriptions of new tumor types, elimination of defunct categories, and updated biological characterization of various tumor types. In particular, the updates pertaining to the following conditions will be reviewed: tumors of the oral cavity and oropharynx, including HPV-positive or HPV-negative squamous cell carcinoma, small cell carcinoma; tumors of the hypopharynx, larynx, trachea, and parapharyngeal space, including nomenclature revisions for laryngeal neuroendocrine tumors; tumors of the nasal cavity and paranasal sinuses including newly added entities such as NUT carcinoma and biphenotypic sinonasal sarcoma; odontogenic and maxillofacial bone tumors, including the reversal of terminology for certain cystic lesions; tumors of the salivary glands, including updated terminology related to high-grade transformation and polymorphous adenocarcinomas tumors; temporal bone lesions including modifications of the nomenclature and classification criteria; tumor-like lesions of the neck and lymph nodes, with a discussion encompassing developmental cysts, metastases of unknown primary, and heterotopia-associated neoplasia; and mucosal melanoma. Read More

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http://dx.doi.org/10.1186/s13244-019-0760-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635538PMC
July 2019
9 Reads

Clinical Reasoning: A misdiagnosis of atypical trigeminal neuralgia.

Neurology 2019 07;93(3):124-131

From the Department of Neurology, Headache Division, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000007790DOI Listing

Minimally-invasive resection of benign tumours of the parotid gland in the parapharyngeal space.

Br J Oral Maxillofac Surg 2019 10 2;57(8):808-809. Epub 2019 Jul 2.

Institute of Maxillofacial Surgery, Quirón-Teknon Medical Centre Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bjoms.2019.06.007DOI Listing
October 2019
2 Reads

Internal jugular vein tumor thrombus due to parapharyngeal extraosseous plasmacytoma.

Radiol Case Rep 2019 Jul 14;14(7):894-896. Epub 2019 May 14.

Haematology Department, Centro Hospitalar Trás-os-Montes e Alto Douro, Avenida da Noruega, 5000 Vila Real, Portugal.

Tumor thrombosis of the internal jugular vein (IJV) represents an uncommon event, usually in the setting of underlying thyroid neoplasms. Extraosseous plasmacytoma (EMP) with tumor thrombosis of the IJV has not yet been reported in the literature. We present a unique case of a plasmacytoma in the left parapharyngeal space with direct extension to the left IJV, documented with contrast enhanced computed tomography and US Doppler. Read More

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http://dx.doi.org/10.1016/j.radcr.2019.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522840PMC
July 2019
9 Reads

[Ganglioneuroma in poststyloid space removed under endoscope through transoral approach: a case report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 May;33(5):468-469;473

Parapharyngeal space refers to the potential space under skull base between masticatory muscles and pharyngeal muscles, ranging from skull base at the top to hyoid bone at the bottom. The outer lateral wall consists of medial pterygoid muscle, deep parotid lobe and lower jawbone, lateral pharyngeal wall, medial pterygoid, deep lobe of parotid gland and mandible constitute the lateral wall, lateral pharyngeal wall forms medial wall, and prevertebral fascia constitutes the posterior wall, generally forming an inverted pyramid lacuna. Parapharyngeal space is divided into prestyloid space and poststyloid space by stylopharygeal fascia. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.05.022DOI Listing
May 2019
2 Reads

Parapharyngeal space paraganglioma: distinguishing vagal paragangliomas from carotid body tumours using standard MRI.

Clin Radiol 2019 Sep 20;74(9):734.e1-734.e6. Epub 2019 May 20.

Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China. Electronic address:

Aim: To evaluate whether standard magnetic resonance imaging (MRI) could distinguish vagal paragangliomas (VPs) from carotid body tumours (CBTs) in the parapharyngeal space.

Methods And Materials: Thirteen VPs in 13 patients and 29 CBTs in 26 patients were included in this study. MRI features were evaluated independently by two head and neck radiologists with 10 and 16 years of experience (X. Read More

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http://dx.doi.org/10.1016/j.crad.2019.04.018DOI Listing
September 2019
6 Reads

Some Considerations on the WHO Histological Classification of Laryngeal Neoplasms.

Adv Ther 2019 07 22;36(7):1511-1517. Epub 2019 May 22.

Epigenetics and Human Disease Laboratory, Department of Biomedical Sciences and Medicine, University of Algarve, Faro, Portugal.

A new edition of the World Health Organization (WHO) Histological classification of tumours of the hypopharynx, larynx, trachea and parapharyngeal space was published in 2017. We have considered this classification regarding laryngeal neoplasms and discuss the grounds for said revision. Many of the laryngeal neoplasms described in the literature and in the previous WHO edition from 2005 have been omitted from this current revision. Read More

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http://dx.doi.org/10.1007/s12325-019-00978-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824387PMC
July 2019
21 Reads

Endoscopic-assisted maxillectomy: Operative technique and control of surgical margins.

Oral Oncol 2019 06 11;93:29-38. Epub 2019 Apr 11.

Unit of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Ospedale di Circolo e Fondazione Macchi, Varese, Italy; Head and Neck Surgery & Forensic Dissection Research Center (HNS&FDRc), Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.

Background: When amenable to radical excision, cancer involving the maxilla is typically treated with maxillectomy followed by adjuvant therapy. Posterior tumor extension beyond the maxillary box leads to the invasion of complex areas, where achieving clear margins may be challenging.

Methods: Patients undergoing endoscopic-assisted maxillectomy for nasoethmoidal, maxillary, or hard palate cancer between 2007 and 2017 were included in the study. Read More

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http://dx.doi.org/10.1016/j.oraloncology.2019.04.002DOI Listing
June 2019
12 Reads

Giant De Novo Pleomorphic Adenoma of Parapharyngeal Space, Can It Cause Spinal Deformity? A Case Report.

Spine Deform 2019 05;7(3):505-508

Department of Pathology, Maulana Azad Medical College and associated Lok Nayak Hospital, Bahadur Shah Zafar Marg, Delhi, 110002, India.

Study Design: Case report.

Introduction: De novo giant pleomorphic adenoma is a rare tumor of the parapharyngeal space (PPS). Tumors of the PPS can grow to a large size, compromising the space of the upper aerodigestive tract. Read More

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http://dx.doi.org/10.1016/j.jspd.2018.09.009DOI Listing
May 2019
9 Reads

Endoscopic transvestibular anatomy of the infratemporal fossa and upper parapharyngeal spaces for clinical surgery: a cadaver study.

Eur Arch Otorhinolaryngol 2019 Jun 16;276(6):1799-1807. Epub 2019 Apr 16.

Department of Otorhinolaryngology-Head and Neck Surgery (Shanghai Key Clinical Disciplines of Otorhinolaryngology), Eye, Ear, Nose and Throat Hospital, Fudan University, Fenyang Road Num83, Xuhui District, Shanghai, 200031, China.

Aims: To investigate the anatomy of the infratemporal fossa (ITF) and to discuss the practicality of endoscopic transvestibular surgery for an ITF tumor.

Methods: Five fresh cadaveric specimens (10 sides) with vascular silicone injection were prepared for endoscopic anatomy. A transvestibular vertical incision was made along the ramus of the mandible, and pivotal nerves, arteries, and muscles were exposed to sculpt the anatomic landmarks of the ITF. Read More

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http://dx.doi.org/10.1007/s00405-019-05410-yDOI Listing
June 2019
9 Reads

Transoral Resection of Giant Parapharyngeal Space Tumors via a Combined Surgical Approach.

Iran J Otorhinolaryngol 2019 Mar;31(103):87-96

Department of Otorhinolaryngology - Head and Neck Surgery, Aristotle University of Thessaloniki, AHEPA Hospital, 1 Stilponos Kyriakidi St, 54636 Thessaloniki, Greece.

Introduction: Parapharyngeal space (PPS) tumors account for 0.5% of the head and neck neoplasms. Based on the evidence, 80% of these tumors are of a benign nature. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449533PMC
March 2019
22 Reads

Chemotherapy-Induced First Bite Syndrome: A Case Report in a Patient With Hodgkin Lymphoma.

Ear Nose Throat J 2019 Jun 8;98(5):E30-E31. Epub 2019 Apr 8.

1 Department of Otolaryngology-Head & Neck Surgery, Washington University School of Medicine in St Louis, St Louis, MO, USA.

Vinca alkaloids are known to cause bilateral jaw pain that occurs once during the chemotherapy course. We report a patient with first bite syndrome (FBS) during active treatment with chemotherapy. A patient with Hodgkin lymphoma presented with unilateral jaw pain after beginning his chemotherapy regimen. Read More

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http://dx.doi.org/10.1177/0145561319840534DOI Listing
June 2019
17 Reads

Surgical Treatment of Primary Parapharyngeal Space Tumors: A Single-Institution Review of 28 Cases.

J Oral Maxillofac Surg 2019 07 13;77(7):1520.e1-1520.e16. Epub 2019 Mar 13.

Professor, Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.

Purpose: This study evaluated the surgical treatment of tumors arising from the parapharyngeal space (PPS) in a single-center setting.

Materials And Methods: This retrospective study was conducted with 28 patients who underwent surgery for primary PPS tumors from 2011 to 2018. Patient clinical features, histologic tumor type, surgical approach, complications, and follow-up data were evaluated. Read More

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http://dx.doi.org/10.1016/j.joms.2019.03.001DOI Listing
July 2019
3 Reads

Vagal schwannomas of the head and neck: A comprehensive review and a novel approach to preserving vocal cord innervation and function.

Head Neck 2019 07 7;41(7):2450-2466. Epub 2019 Apr 7.

THANC (Thyroid, Head and Neck Cancer) Foundation, New York, New York.

Background: Schwannomas, benign tumors arising from neurolemmocytes, are the most common type of peripheral nerve tumors. Extracranial schwannomas are most often found in the parapharyngeal space, commonly involving the vagus nerve to cervical sympathetic trunk. Vagal schwannomas present several unique clinical and therapeutic challenges. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/hed.25758
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http://dx.doi.org/10.1002/hed.25758DOI Listing
July 2019
27 Reads

[Expert consensus on processes and operations of navigation-guided needle biopsy techniques for skull base tumors].

Authors:

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Apr;54(4):228-233

Skull base surgery is an interdisciplinary subject. The anatomical structures in the skull base related to oral and maxillofacial surgery include parapharyngeal space, pterygopalatine fossa and infratemporal space. This operative area is one of the most challenging surgical areas in oral and maxillofacial surgery due to its deep site, complex anatomy and high risk. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1002-0098.2019.04.003DOI Listing
April 2019
7 Reads

Comprehensive Analyses of Intraoral Benign and Malignant Nerve Sheath Tumors: The Rare Disease Entities Revisited.

J Craniofac Surg 2019 Jun;30(4):e317-e327

Department of Oral and Maxillofacial Surgery, College of Stomatology.

Introduction: Intraoral benign and malignant nerve sheath tumors (BNST and MNST) are rare tumors with non-specific clinical presentations and represent diagnostic and therapeutic challenges. Current knowledge regarding their demographic, clinicopathological features and treatments remains fragmented.

Materials And Methods: The original data about patients diagnosed as intraoral BNST and MNST were retrieved from our disease registry (2005-2017). Read More

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http://dx.doi.org/10.1097/SCS.0000000000005231DOI Listing
June 2019
10 Reads

Locally advanced mammary analogue secretory carcinoma of the parotid gland.

Int J Oral Maxillofac Surg 2019 Jul 15;48(7):865-868. Epub 2019 Feb 15.

Department of Oral and Maxillofacial Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, Japan. Electronic address:

Mammary analogue secretory carcinoma (MASC) has recently been recognized as a salivary gland tumour that is characterized by the ETV6-NTRK3 fusion gene. A case of locally advanced MASC of the parotid gland in a 67-year-old man is presented here. The patient visited the hospital due to a large right infra-auricular mass, which had been enlarging gradually over a period of 2years. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09015027193004
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http://dx.doi.org/10.1016/j.ijom.2019.01.027DOI Listing
July 2019
3 Reads

Transoral robotic surgery for the parapharyngeal space: expanding the transoral corridor.

J Robot Surg 2020 Feb 14;14(1):61-67. Epub 2019 Feb 14.

Department of Otolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, Teaching Block, 4th, Floor, New Delhi, 110029, India.

To analyze the feasibility, surgical outcomes and possible risks and complications encountered during transoral robotic surgery (TORS) for approaching parapharyngeal space (PPS) tumours, a retrospective cohort study was conducted. Out of 108 TORS procedures performed, 5 PPS tumours were identified from May 2011- November 2017. This study included 2 retrostyloid (benign nerve sheath tumour) and 3 prestyloid tumours (pleomorphic adenoma), of which one patient had previously undergone a transcervical approach for deep lobe of parotid pleomorphic adenoma. Read More

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http://link.springer.com/10.1007/s11701-019-00932-3
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http://dx.doi.org/10.1007/s11701-019-00932-3DOI Listing
February 2020
14 Reads

[Clinical analysis and surgical treatment evaluation of 23 cases with primary parapharyngeal space tumors].

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Feb;54(2):107-111

Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China.

To analyze the clinical characters and surgical treatment of primary parapharyngeal space (PPS) tumors. A total of 23 cases of primary PPS tumors which were treated from November 2011 to December 2017 were included for the retrospective analysis in this study. Twenty-three cases of patients with primary PPS tumors were analyzed in this study. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1002-0098.2019.02.006DOI Listing
February 2019
7 Reads

A novel combined transoral and transcervical surgical approach for recurrent metastatic medullary thyroid cancer to the parapharyngeal space.

J Robot Surg 2020 Feb 28;14(1):233-236. Epub 2019 Jan 28.

Otolaryngology Head and Neck Surgery Department, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.

Medullary thyroid cancer (MTC) represents less than 1% of all thyroid cancers. Complete surgical resection remains the mainstay of treatment for locoregional disease. Unfortunately, patients with recurrence may present with metastasis to challenging anatomic locations. Read More

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http://dx.doi.org/10.1007/s11701-019-00930-5DOI Listing
February 2020
4 Reads

Parapharyngeal Ganglioneuroma Detected by 18F-FDG PET/CT in a Patient With Hodgkin Lymphoma.

Clin Nucl Med 2019 Mar;44(3):240-243

Pathology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan.

A 38-year-old woman with anterior mediastinal Hodgkin lymphoma underwent F-FDG PET/CT, revealing abnormal uptake at the left retrostyloid parapharyngeal space. After chemotherapy, follow-up PET/CT showed regression of previously avid lesions but not the left retropharyngeal mass. Subsequent MRI revealed findings suggestive of neurogenic tumor. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002444DOI Listing
March 2019
11 Reads

Recurrent Desmoid Tumor of the Neck: A Case Report of a Benign Disease with Aggressive Behavior.

Case Rep Otolaryngol 2018 28;2018:6573587. Epub 2018 Nov 28.

Department of Otorhinolaryngology, University of Crete Medical School, Heraklion, Crete, Greece.

We present a case of a desmoid tumor recurrence in a patient with a history of a resected desmoid tumor of the right neck area with free surgical margins six months earlier. The neoplasm was found to invade the parapharyngeal space, and wide excision was performed including most of the sternocleidomastoid muscle (SCM), the thrombosed internal jugular vein (IJV), and the infiltrated spinal accessory nerve (SAN). The histopathologic findings displayed free microscopic margins, with close margins at the site of the parapharyngeal space extension. Read More

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https://www.hindawi.com/journals/criot/2018/6573587/
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http://dx.doi.org/10.1155/2018/6573587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304189PMC
November 2018
8 Reads

Radiotherapy for parapharyngeal space tumors.

Am J Otolaryngol 2019 Mar - Apr;40(2):289-291. Epub 2018 Dec 21.

Coordinator of the International Head and Neck Scientific Group, Padua, Italy.

A wide variety of tumors, both benign and malignant, occur in the parapharyngeal space. Depending on histology and extent, treatment may include surgery and/or radiotherapy (RT). Herein we discuss the role of RT in the management of some of the more commonly encountered neoplasms, including salivary gland tumors, paragangliomas, schwannomas, and soft-tissue sarcomas. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.12.010DOI Listing
June 2019
12 Reads

Classification of tumors by imaging diagnosis and preoperative fine-needle aspiration cytology in 120 patients with tumors in the parapharyngeal space.

Head Neck 2019 05 8;41(5):1277-1281. Epub 2019 Jan 8.

Otorhinolaryngology and Head and Neck Surgery, Kitasato University, Kanagawa, Japan.

Background: Tumors in the parapharyngeal space are rare, and preoperative diagnosis is difficult because of anatomical and histological complexity.

Methods: To evaluate the usefulness of preoperative diagnosis, we compared the classification of tumor localization in the prestyloid and retrostyloid compartments by imaging and preoperative cytological diagnosis by fine-needle aspiration cytology with the postoperative histopathological diagnosis in 120 patients with tumors in the parapharyngeal space.

Results: Tumors were located in the prestyloid and retrostyloid compartments in 68 and 52 patients, respectively. Read More

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http://doi.wiley.com/10.1002/hed.25552
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http://dx.doi.org/10.1002/hed.25552DOI Listing
May 2019
34 Reads

Oral core-needle biopsy in the diagnosis of malignant parapharyngeal space tumors.

Am J Otolaryngol 2019 Mar - Apr;40(2):233-235. Epub 2018 Nov 22.

Department of Otolaryngology-Head and Neck, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Objective: To confirm the pre-treatment diagnosis of parapharyngeal space malignancy could aid the treatment plan.

Methods: For patients with suspected malignant parapharyngeal space tumors following preoperative imaging, oral biopsy was conducted for pathological diagnosis with the use of 22-G biopsy needles.

Results: A total of 11 patients were enrolled. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.11.005DOI Listing
June 2019
7 Reads