1,226 results match your criteria Parapharyngeal Space Tumors


Complete resection of a huge parapharyngeal lesion without neurovascular injuries poses a big challenge.

J Surg Case Rep 2021 Apr 22;2021(4):rjab134. Epub 2021 Apr 22.

Faculty of Medicine, Tishreen University, Lattakia, Syria.

Pleomorphic adenoma is the most common salivary gland neoplasm, accounting for 63% of all parotid gland tumors. Most tumors originate in the superficial lobe but, more rarely, these tumors may involve the deep lobe of the parotid gland, growing medially and occupying the parapharyngeal space (PPS). Our case presents a 48-year-old man with an extremely huge recurrent parapharyngeal lesion that bulging in the nasopharynx and the oropharynx and significantly comprised the airways. Read More

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Parapharyngeal Space Angiofibroma: A Diagnostic Surprise.

Iran J Otorhinolaryngol 2021 Mar;33(115):107-111

Department of Histopathology, PGIMER, Chandigarh, India.

Introduction: Angiofibromas classically develop in the lateral wall of the nasopharynx from the sphenopalatine region. Extra-nasopharyngeal angiofibromas are rare entities, with the maxillary sinus being the most common site. Parapharyngeal angiofibroma is an extremely rare entity, being seldom reported in English literature. Read More

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Combined approach for malignant tumours of the deep lobe of the parotid involving the stylomandibular tunnel and parapharyngeal space.

Oral Oncol 2021 Apr 26:105283. Epub 2021 Apr 26.

Head and Neck Oncology, Chris O'Brien Lifehouse, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia. Electronic address:

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The development of a clinical algorithm for the diagnosis of tumours in the parapharyngeal space. A systematic review.

Acta Otorrinolaringol Esp 2021 Mar 30. Epub 2021 Mar 30.

Sección de Cirugía de Cabeza y Cuello, Servicio de Cirugía General, Hospital Nacional Profesor A. Posadas, El Palomar, Buenos Aires, Argentina.

Introduction: Parapharyngeal space (PPS) is defined as a deep space, located around the upper pharynx, in the shape of an inverted pyramid. Primary tumours in this region are rare, accounting for 0.5% of head and neck neoplasms, and most are benign. Read More

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[Analysis of efficacy of coblation assisted endoscope system for the treatment of parapharyngeal space tumors with transoral approach].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Mar;35(3):204-208

Department of Otorhinolaryngology,the First Affiliated Hospital,Nanjing Medical University,Nanjing,210029,China.

To summarize and analyze the feasibility, safety and efficacy of parapharyngeal space surgery assisted by coblation and endoscopic system with transoral approach. The data of 20 patients with parapharyngeal space tumors were retrospectively analyzed. All the patients underwent CT and/or MRI examination before surgery, and all underwent transoral approach assisted by coblation and endoscopic systems. Read More

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Pedicle Corridors and Vessel Options for Free Flap Reconstruction following Endoscopic Endonasal Skull Base Surgery: A Systematic Review.

J Neurol Surg B Skull Base 2021 Apr 12;82(2):196-201. Epub 2019 Sep 12.

Department of Otolaryngology-Head and Neck Surgery, Washington University in St Louis, Saint Louis, Missouri, United States.

 Microvascular free flaps offer an alternative to local and regional flaps for coverage of complex or large skull base defects. Routes and approaches to these reconstructive options are complicated and require an understanding of complex head and neck anatomy.  A systematic review of the literature was performed using a set of search terms with the help of a qualified librarian. Read More

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Oropharyngeal neuroglial choristoma with extension into the parapharyngeal space.

Radiologia 2021 Mar 24. Epub 2021 Mar 24.

Radiólogo, Hospital Pequeno Príncipe, Curitiba, Paraná, Brasil.

Oropharyngeal neuroglial choristomas are exceptionally rare head and neck tumours that contain mature neuroglial tissue. We report a case of neuroglial choristoma centred in the oropharynx and extending into the parapharyngeal space that, to the best of our knowledge, is the only case whose appearance simulated brain cortical gyri with an apparent differentiation between white and grey matter. We illustrate and detail the magnetic imaging findings of oropharyngeal choristoma that might help to establish a correct preoperative diagnosis. Read More

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Radiotherapy of extraosseous nasopharyngeal chordoma: A case report and literature review.

Authors:
Chi-Yuan Yeh

Mol Clin Oncol 2021 Apr 26;14(4):84. Epub 2021 Feb 26.

Department of Radiation Oncology, Tungs' Taichung Metroharbor Hospital, Taichung 43503, Taiwan, R.O.C.

Chordomas are slow-growing aggressive tumors that account for 1-4% of all bone tumors. The anatomical distribution of chordomas includes 50-60% in the sacrococcygeal region, 25-30% in the skull base and 15% in the mobile spine. Virchow was the first to describe and term these tumors as 'ecchordosis physaliphora' in 1857, and Muller established their notochordal origin in 1895. Read More

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Primary neoplasms of the parapharyngeal space: diagnostic and therapeutic pearls and pitfalls.

Eur Arch Otorhinolaryngol 2021 Mar 19. Epub 2021 Mar 19.

Department of Otorhinolaryngology - Head and Neck Surgery, Inselspital, Bern University Hospital, Freiburgstrasse, 3010, Bern, Switzerland.

Purpose: Parapharyngeal space neoplasms (PSNs) are rare tumors of the head and neck region. In this study, we report our institutional experience with PSNs over a 27-years period.

Methods: Patients treated between 1992 and 2018 were identified through our tumor board database. Read More

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Chondrosarcoma of the parapharyngeal space: Case report and literature review of an extremely rare location.

Radiol Case Rep 2021 May 26;16(5):1099-1102. Epub 2021 Feb 26.

Department of Radiotherapy, Faculty of Medicine, Mohammed VI University of Health Sciences/Cheikh Khalifa International University Hospital, 82403, Oum Rabii, Hay Hassani, Casablanca, Morocco.

Chondrosarcoma of the head and neck region is a rare disease, representing approximately 0.1% of all head and neck neoplasms. Parapharyngeal location is extremely rare and low-grade ones are even rarer. Read More

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A rare case of cervical hypoglossal nerve neurofibromas in a patient with type 1 neurofibromatosis.

Braz J Otorhinolaryngol 2021 Feb 25. Epub 2021 Feb 25.

Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia Medical Centre, Department of Otorhinolaryngology - Head & Neck Surgery, Kuala Lumpur, Malaysia; National University of Malaysia, Faculty of Medicine, Kuala Lumpur, Malaysia. Electronic address:

Background: Neurofibromas are benign peripheral nerve sheath tumours. Hypoglossal nerve neurofibromas in cervical region are relatively rare, bilateral occurrence is extremely rare.

Methods: A 32-year-old man with type 1 neurofibromatosis presented with bilateral neck masses. Read More

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February 2021

Extended Anterolateral Infralabyrinthine Transjugular Approach for Microsurgical Resection of Giant Glomus Vagale Tumor: Operative Video and Technical Nuances.

J Neurol Surg B Skull Base 2021 Feb 26;82(Suppl 1):S59-S60. Epub 2020 Nov 26.

Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Neurological Institute of New Jersey, Saint Barnabas Medical Center, RWJ Barnabas Health, Newark, New Jersey, United States.

Glomus vagale tumor is a paraganglioma of the vagus nerve. It is a rare type of benign tumor that occupies the head and neck and skull base regions. Patients often present with lower cranial nerve dysfunctions such as difficulty swallowing, tongue weakness, and hoarseness. Read More

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February 2021

The intraoral growth patterns of parapharyngeal tumors: A proposed classification system.

Ear Nose Throat J 2021 Mar 9:145561321997557. Epub 2021 Mar 9.

Department of Otolaryngology-Head and Neck Surgery, 12667Beijing Anzhen Hospital, Capital Medical University, Chaoyang District, Beijing, People's Republic of China.

Objective: Nearly half of parapharyngeal space (PPS) tumors present as an intraoral mass, which is diagnostically challenging. In this study, we studied whether preoperative growth patterns were associated with histopathological diagnosis for planning surgery.

Methods: We performed a cross-sectional study in patients with PPS tumors. Read More

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Giant deep lobe parotid tumor removal via total parotidectomy without mandibulotomy. A simple and safe technique.

J Clin Exp Dent 2021 Mar 1;13(3):e313-e317. Epub 2021 Mar 1.

MD, PhD. Head of the Department of Otorhinolaryngology, La Fe University and Polytechnic Hospital, Valencia, Spain. Professor of the Department of Surgery, Faculty of Medicine, Valencia University, Valencia, Spain.

The transmandibular route is often combined with the transparotid-transcervical approach when extensive surgical field exposure is required, as in the case of deep parotid lobe tumors measuring over 4 cm in size. This procedure implies great morbidity and prolongs surgery time. Furthermore, in cases where additional lip division is performed, the aesthetic outcomes may be poorer. Read More

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Repeated loss of consciousness as the first symptom of recurrence of head and neck malignancy: a case report.

Eur Heart J Case Rep 2021 Jan 4;5(1):ytaa430. Epub 2021 Jan 4.

Department of Cardiovascular Medicine, National Cerebral & Cardiovascular Centre, 6-1 Kishibeshinmachi, Suita, Osaka 564-8565, Japan.

Background: Head and neck malignancies rarely cause reflex syncope. Three mechanistic patterns of reflex syncope are known in such patients: carotid sinus syndrome, glossopharyngeal neuralgia syndrome, and parapharyngeal space lesions syncope syndrome. There are few reports describing parapharyngeal space lesions syncope syndrome. Read More

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January 2021

Dumbbell-shaped solitary fibrous tumor in the parapharyngeal space: A case report.

World J Clin Cases 2021 Feb;9(5):1204-1209

Department of Otolaryngology Head and Neck Surgery, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China.

Background: Solitary fibrous tumors (SFTs) occurring in the parapharyngeal space are rare, and their final diagnosis depends on pathological and immunohistochemical analyses. Once the tumor is diagnosed, complete resection and regular postoperative follow-up are required.

Case Summary: A 40-year-old male patient with a right parotid gland mass discovered 8 years ago was admitted to hospital. Read More

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February 2021

Mandibular access osteotomy: Gate way to parapharyngeal space - A case report.

Int J Surg Case Rep 2021 Mar 22;80:105683. Epub 2021 Feb 22.

KIMS Hospital, India.

Introduction: Para pharyngeal tumors often pose a challenge to surgeons for surgical interventions. Maxillofacial access osteotomies offer excellent visualization and permit unhindered surgical manipulation. Access osteotomy allows the surgeon an adequate access of the surgical field to resect the tumor completely and to preserve vital structures. Read More

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Endoscopy-Assisted Transoral Approach to Resect Parapharyngeal Space Tumors: A Systematic Review and Meta-Analysis.

Laryngoscope 2021 Feb 22. Epub 2021 Feb 22.

Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.

Objectives: By comparing the endoscopy-assisted transoral approach (EATA) with external approaches (EAs) for the resection of parapharyngeal space tumors (PPSTs), we determined whether the EATA has advantages in terms of operation time, intraoperative bleeding volume, postoperative hospitalization, drainage volume, and complications. At the same time, we summarized the surgical indications for the EATA.

Methods: Systematic literature retrieval was performed in the PubMed, Web of Science, Embase, CNKI, Wanfang, and CQVIP databases up to February 2020. Read More

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February 2021

Endoscopic surgery compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma: a multicentre, open-label, randomised, controlled, phase 3 trial.

Lancet Oncol 2021 03 15;22(3):381-390. Epub 2021 Feb 15.

Department of Otolaryngology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou Key Laboratory of Otorhinolaryngology, Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, China; Department of Otolaryngology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Electronic address:

Background: The role of surgery compared with reirradiation in the primary treatment of patients with resectable, locally recurrent nasopharyngeal carcinoma (NPC) who have previously received radiotherapy is a matter of debate. In this trial, we compared the efficacy and safety outcomes of salvage endoscopic surgery versus intensity-modulated radiotherapy (IMRT) in patients with resectable locally recurrent NPC.

Methods: This multicentre, open-label, randomised, controlled, phase 3 trial was done in three hospitals in southern China. Read More

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[Ameloblastic craniopharyngioma in parapharyngeal space: a case report].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Feb;56(2):168-170

Department of Otorhinolaryngology Head and Neck Surgery, the First Hospital of Jilin University, Changchun 130021, China.

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February 2021

Endoscopically assisted transoral resection of a Bailey type IV second branchial cleft cyst: A case report.

Medicine (Baltimore) 2021 Jan;100(3):e24375

Department of Otolaryngology-Head and Neck Surgery.

Rationale: The diagnosis of type IV branchial cleft cyst (BCC) according to the Bailey classification is very challenging due to lack of specific clinical manifestations in the early stage of the disease. Here, we present the transoral surgical route of endoscopic resection of second BCC in the parapharyngeal space (PPS) with good outcomes.

Patient Concerns: A 21-year-old man with a 1-year history of snoring complained about sore throat for 1 month and a fever that lasted for 3 days. Read More

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January 2021

Mixed response and mechanisms of resistance to larotrectinib in metastatic carcinoma ex pleomorphic adenoma of the parotid harboring an NTRK2 fusion: A case report.

Medicine (Baltimore) 2021 Jan;100(4):e24463

Swiss Tumor Molecular Institute, Zurich, Switzerland.

Introduction: Standardized systemic treatment options are lacking for carcinoma ex pleomorphic adenoma, which is a rare and aggressive tumor primarily found in salivary glands.Here we report the case of a 63-year-old male with carcinoma ex pleomorphic adenoma of the left parotid and parapharyngeal space harboring a neurotrophic receptor tyrosine kinase (NTRK) 2 fusion who was treated with a small molecule inhibitor that targets the tropomyosin receptor kinase (TRK) proteins. To the best of our knowledge, no similar case has been described in the literature so far. Read More

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January 2021

Transoral Parotidectomy.

Authors:
Ryan F Osborne

Oral Maxillofac Surg Clin North Am 2021 May 19;33(2):169-175. Epub 2021 Jan 19.

Osborne Head and Neck Institute, Cedars-Sinai Medical Towers, 8631 West Third Street Suite 945E, Los Angeles, CA 90048, USA. Electronic address:

Transoral parotidectomy allows for the management of parapharyngeal space tumors and accessory parotid gland tumors without the need for a transfacial/transparotid or mandible splitting procedure. It is a minimally invasive approach that permits a faster recovery and with a lesser risk of facial palsy. Read More

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A case of parapharyngeal space salivary duct cyst with fine needle biopsy suspicious for squamous cell carcinoma.

Am J Otolaryngol 2021 May-Jun;42(3):102924. Epub 2021 Jan 13.

Department of Otolaryngology - Head and Neck Surgery, University of Missouri School of Medicine, Columbia, MO, USA.

Objectives: To report a unique case of salivary duct cyst presenting as parapharyngeal space mass and review relevant literature regarding salivary duct cyst and fine needle aspiration biopsy of salivary gland lesions.

Methods: After a case description, a review of the literature regarding salivary duct cyst etiology, pathophysiology, presentation, histologic features, and the accuracy of FNA in the context of salivary gland lesions was conducted.

Results: Salivary duct cysts are rare, often acquired, cystic dilatations of salivary ducts thought to arise secondary to ductal obstruction, commonly occurring in the major salivary glands. Read More

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January 2021

Transoral Approach to the Giant Deep Lobe Parotid Gland Pleomorphic Adenoma.

J Craniofac Surg 2021 Jan 14. Epub 2021 Jan 14.

Department of Otolaryngology, Head and Neck Surgery, Baskent University Faculty of Medicine, Ankara, Turkey.

Abstract: Parapharyngeal space tumors are rare tumors that make up about 0.5% to 1% of all head and neck neoplasms. The majority of parapharyngeal space tumors, which are usually benign, consist of salivary gland tumors and neurogenic tumors. Read More

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January 2021

A Rare Case of Extracranial Schwannoma of the Hypoglossal Nerve Located in the Parapharyngeal Space Mimicking a Deep Neck Abscess.

Ear Nose Throat J 2021 Jan 18:145561320988365. Epub 2021 Jan 18.

Department of Oral and Maxillofacial Sciences, Sapienza University, Rome, Italy.

Schwannomas are neurogenic benign tumors originating from the myelin sheath of peripheral nerves, and hypoglossal Schwannomas account for 5% of nonvestibular ones. Extracranial localizations are substantially rare, especially those affecting exclusively the parapharyngeal space; for this reason, the retrostyloid neoformations could initially masquerade as a carotid tumor or deep organized neck abscess. The purpose of this report is to highlight the importance of a multidisciplinary approach in the correct management of differential diagnosis. Read More

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January 2021

Management of a prestyloid parapharyngeal first branchial cleft cyst from puncture to surgical excision and how a routine procedure can turn into an emergency.

Authors:
Lukas S Fiedler

BMJ Case Rep 2021 Jan 12;14(1). Epub 2021 Jan 12.

Otorhinolaryngology and Head and Neck Surgery, Klinikum Mutterhaus der Borromäerinnen gGmbH, Trier, Deutschland, Germany

The anatomy of the parapharyngeal space (PPS) is complex and the differential diagnosis of tumours in this area broad. Although primary tumours of the PPS account for only 0.5% of head and neck neoplasms and are benign lesions in 80% of the cases, the surgical management is crucial and needs specific planning and evaluation of CT and/or MRI scans. Read More

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January 2021

[Imaging of the parapharyngeal space tumors and selection of the treatment].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Oct;34(10):937-941

Department of Otorhinolaryngology,the First Affiliated Hospital of Chongqing Medical University,Chongqing,400012,China.

To analyze the imaging features of parapharyngeal space tumors, and to guide the choice of treatment. A retrospective analysis of 75 cases' clinical data of parapharyngeal space tumor was carried out. All patients underwent enhanced CT and/or enhanced MRI, those tumors closely related to blood vessels and vascular tumors were examined by CTA or MRA, those closely related to peripheral nerves were examined by MRN. Read More

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October 2020

Nodular Oncocytic Hyperplasia of Bilateral Parotid Glands With Parapharyngeal Space Extension.

Ear Nose Throat J 2020 Nov 20:145561320973786. Epub 2020 Nov 20.

Department of Pathology and Laboratory Medicine, 38024Kaohsiung Veterans General Hospital, Kaohsiung.

Oncocytic tumors comprise a group of rare benign neoplasm of salivary glands, accounting for less than 1% of all salivary gland tumors. Nodular oncocytic hyperplasia characterized by multiple unencapsulated oncocytic nodules in the salivary glands is an extremely rare condition. We report a case of bilateral nodular oncocytic hyperplasia of parotid glands with parapharyngeal space extension in an 80-year-old woman whose initial presentation was recurrent parotitis. Read More

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November 2020

Parapharyngeal Neuroglial Heterotopia: A Case Report and Literature Review.

Am J Case Rep 2020 Nov 6;21:e926300. Epub 2020 Nov 6.

Department of Otolaryngology - Head and Neck Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.

BACKGROUND Pediatric neck masses have a wide differential diagnosis. Neuroglial heterotopia is a rare condition that was first described by Reid in 1852. The majority of neuroglial heterotopias are found in the nasal cavity (mistakenly termed as nasal glioma), but they can also occur in extra-nasal areas such as the scalp, orbit, palate, neck, and other areas. Read More

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November 2020