4 results match your criteria Paraneoplastic Diseases* Dermatology

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Dermatology in the Diagnosis of Noncutaneous Malignancy: Paraneoplastic Diseases.

Dermatol Clin 2019 Oct 10;37(4):537-544. Epub 2019 Jul 10.

Oregon Health & Science University, 3303 Southwest Bond Avenue CH16D, Portland, OR 97239, USA.

It is important to recognize paraneoplastic dermatoses because they allow the practitioner to begin an early, directed workup to detect an underlying malignant neoplasm. In this review, several paraneoplastic dermatoses are outlined using existing data to detail each one's association with underlying malignancy, demographics, prognosis, and treatment considerations. Read More

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http://dx.doi.org/10.1016/j.det.2019.05.011DOI Listing
October 2019
5 Reads

Tumour TIF1 mutations and loss of heterozygosity related to cancer-associated myositis.

Rheumatology (Oxford) 2018 02;57(2):388-396

Internal Medicine Department, Vall d'Hebron University Hospital, Barcelona, Spain.

Objectives: To analyse the influence of genetic alterations and differential expression of transcription intermediary factor 1 (TIF1) genes in the pathophysiology of cancer-associated myositis (CAM).

Methods: Paired blood and tumour DNA samples from patients with anti-TIF1γ-positive CAM and from controls were analysed by whole-exome sequencing for the presence of somatic mutations and loss of heterozygosity (LOH) in their TIF1 genes. The genesis and maintenance of the autoimmune process were investigated immunohistochemically by studying TIF1γ expression in the different tissues involved in CAM (skin, muscle and tumour) based on the immunohistochemical H-score. Read More

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http://dx.doi.org/10.1093/rheumatology/kex413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850766PMC
February 2018
16 Reads

Acral manifestations of paraneoplastic and collagen vascular diseases.

Authors:
Ülker Gül

Clin Dermatol 2017 Jan - Feb;35(1):50-54. Epub 2016 Sep 10.

Department of Dermatology, Akdeniz University, Faculty of Medicine, Antalya, Turkey. Electronic address:

The skin often signals a number of systemic disease, making skin findings of paramount significance. Paraneoplastic diseases and collagen vascular diseases are vitally important illnesses. Paraneoplastic diseases and collagen vascular diseases may also occur with many different acral skin findings. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2016.09.007DOI Listing
June 2017
20 Reads

Life-threatening paraneoplastic cutaneous syndromes.

Clin Dermatol 2005 May-Jun;23(3):301-6

Division of Dermatology, Southern Illinois University School of Medicine, Springfield, 55026, USA.

Paraneoplastic syndromes are diseases or symptom complexes associated with malignancy, usually internal. In dermatology, we modify the definition to refer to dermatoses associated with internal malignancy. In this article, we discuss the link between malignancy and such dermatologic disorders as acanthosis nigricans, acrokeratosis paraneoplastica of Bazex, dermatomyositis, erythema gyratum repens, necrolytic migratory erythema (glucagonoma syndrome), and paraneoplastic pemphigus and discuss, where such information is known, the mechanism by which these paraneoplastic diseases occur. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2004.06.011DOI Listing
September 2005
14 Reads
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