660 results match your criteria Paraganglioma of the Bladder

Paraganglioma of the bladder: A case report.

Asian J Surg 2021 May 10. Epub 2021 May 10.

Department of Endocrinology, Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China. Electronic address:

View Article and Full-Text PDF

[Bladder paraganglioma: Report of two cases and a literature review.]

Arch Esp Urol 2021 May;74(4):445-449

Servicio de Oncología Médica. Hospital General Universitario de Elche. España. Unidad de Consejo Genético. Hospital General Universitario de Elche. España.

Objective: Description of two incidental cases of bladder paraganglioma in women and review of the published literature.

Methods: A bibliographic search was carried out in Medline over the last 10 years according to the terms "urinary bladder" and "paraganglioma".

Results: Bladder paraganglioma (BP) accounts for less than 0. Read More

View Article and Full-Text PDF

Paraganglioma of Urinary Bladder in a Pediatric Patient.

Cureus 2021 Mar 18;13(3):e13964. Epub 2021 Mar 18.

Department of Anaesthesiology, Ghulab Devi Hospital, Al-Aleem Medical College, Lahore, PAK.

Paragangliomas arise from neural cells and are found in different anatomical locations in the body. Paragangliomas in the adrenal glands are called pheochromocytoma, while the others are known as extra-adrenal paragangliomas. They are usually benign and are extremely rare in children. Read More

View Article and Full-Text PDF

Oncology and complications.

Arch Ital Urol Androl 2021 Mar 19;93(1):71-76. Epub 2021 Mar 19.

Urology Department, General Hospital of Athens "G. Gennimatas", Athens.

This collection of cases describes some unusual urological tumors and complications related to urological tumors and their treatment. Case 1: A case of uretero-arterial fistula in a patient with long-term ureteral stenting for ureteral oncological stricture and a second case associated to retroperitoneal fibrosis were described. Abdominal CT, pyelography, cystoscopy were useful to show the origin of the bleeding. Read More

View Article and Full-Text PDF

First-in-Human Application of Terbium-161: A Feasibility Study Using Tb-DOTATOC.

J Nucl Med 2021 Feb 5. Epub 2021 Feb 5.

Center for Radiopharmaceutical Science PSI/ETHZ/USZ Paul Scherrer Institute, Switzerland.

Tb has similar decay properties as Lu but, additionally, emits a substantial number of conversion and Auger electrons. The aim of this study was to apply Tb in a clinical setting and to investigate the feasibility to visualize the physiological and tumor biodistribution of Tb-DOTATOC. Tb was shipped from Paul Scherrer Institute, Switzerland, to Zentralklinik Bad Berka, Germany, where it was used for the radiolabeling of DOTATOC. Read More

View Article and Full-Text PDF
February 2021

Extending Horizon of Robotic Surgery to Bladder-Preserving Approach for Vesical Paraganglioma: Rare Case with Unusual Presentation.

J Endourol Case Rep 2020 29;6(4):319-321. Epub 2020 Dec 29.

Department of Urology, All India Institute of Medical Science (AIIMS), Rishikesh, Uttarakhand, India.

Vesical paraganglioma is rare and accounts for <0.1% of all urinary bladder tumors. They are mostly functional because of secretion of catecholamines and clinical presentation may mimic like a hyperfunctioning adrenal pheochromocytoma. Read More

View Article and Full-Text PDF
December 2020

Whole Exome Sequencing Identifies Novel Genetic Alterations in Patients with Pheochromocytoma/Paraganglioma.

Endocrinol Metab (Seoul) 2020 12 23;35(4):909-917. Epub 2020 Dec 23.

Department of Laboratory Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Background: Pheochromocytoma and paragangliomas (PPGL) are known as tumors with the highest level of heritability, approximately 30% of all cases. Clinical practice guidelines of PPGL recommend genetic testing for germline variants in all patients. In this study, we used whole exome sequencing to identify novel causative variants associated with PPGL to improve the detection of rare genetic variants in our cohort. Read More

View Article and Full-Text PDF
December 2020

Well-differentiated neuroendocrine tumors of the lower urinary tract: biologic behavior of a rare entity.

Hum Pathol 2021 Mar 8;109:53-58. Epub 2020 Dec 8.

Department of Pathology, Johns Hopkins Hospital, Baltimore, MD, 21287, USA; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, 35233, USA. Electronic address:

The spectrum of neuroendocrine (NE) tumors in the genitourinary tract ranges from the aggressive large and small cell carcinomas to the often benign paraganglioma and well-differentiated neuroendocrine tumor (WD-NET). At least 15 pure lower urinary tract (LUT) WD-NETs have been described. Owing to the rarity of WD-NET in the LUT and the limited number of reported cases, a better definition of their biologic long-term behavior is warranted. Read More

View Article and Full-Text PDF

Pan-Cancer Multiomics Analysis of TC2N Gene Suggests its Important Role(s) in Tumourigenesis of Many Cancers.

Asian Pac J Cancer Prev 2020 Nov 1;21(11):3199-3209. Epub 2020 Nov 1.

Department of Pathology, Dow International Medical College, Dow University of Health Sciences Karachi, Pakistan.

Background: Role of TC2N in carcinogenesis has been largely unfathomed until recently when it was identified as a novel oncogene in lung cancer. Subsequently, a tumour suppressor role of TC2N was reported in breast cancer. It is therefore highly relevant to investigate TC2N molecular partners/mechanisms on a larger scale including a wider range of tumour types. Read More

View Article and Full-Text PDF
November 2020

Integrative omics analysis reveals relationships of genes with synthetic lethal interactions through a pan-cancer analysis.

Comput Struct Biotechnol J 2020 21;18:3243-3254. Epub 2020 Oct 21.

Jiangsu Key Laboratory for Molecular and Medical Biotechnology, School of Life Science, Nanjing Normal University, Nanjing 210023, China.

Synthetic lethality is thought to play an important role in anticancer therapies. Herein, to understand the potential distributions and relationships between synthetic lethal interactions between genes, especially for pairs deriving from different sources, we performed an integrative analysis of genes at multiple molecular levels. Based on inter-species phylogenetic conservation of synthetic lethal interactions, gene pairs from yeast and humans were analyzed; a total of 37,588 candidate gene pairs containing 7,816 genes were collected. Read More

View Article and Full-Text PDF
October 2020

Bladder paraganglioma: a case report.

Pan Afr Med J 2020 25;36:339. Epub 2020 Aug 25.

Serviço de Urologia, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal.

Bladder Paraganglioma is a rare type of bladder tumor (0.06%). It is typically benign and the most common symptoms are hematuria, hypertension and headache. Read More

View Article and Full-Text PDF
January 2021

Approach to Treatment of a Non-functional Retrovesical Bladder Paraganglioma.

J Coll Physicians Surg Pak 2020 Oct;30(10):1113-1114

Department of Urology, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.

Null. Read More

View Article and Full-Text PDF
October 2020

Urinary bladder pheochromocytoma managed with TURBT. Case report and review of literature.

Urol Case Rep 2020 Nov 2;33:101291. Epub 2020 Jun 2.

Mutah university, faculty of medicine, department of urology, karak, 61710, Jordan.

Bladder pheochromocytomas are rare catecholamine-secreting tumours of chromaffin cells. Sympathetic system stimulation due to Catecholamine over secretion during micturation is the most common presentation. Unsuspected bladder pheochromocytoma can result in hypertensive crisis during transurethral resection of bladder tumor (TURBT). Read More

View Article and Full-Text PDF
November 2020

Superficial siderosis of the central nervous system in a patient with asymptomatic sacral paraganglioma as source of chronic bleeding.

Rev Neurol 2020 Oct;71(7):253-256

Hospital Universitario La Fe, Valencia, España.

Introduction: Superficial siderosis of the central nervous system is an infrequent pathology secondary to chronic bleeding into the cerebrospinal fluid. Spinal tumors are infrequent cause of superficial siderosis being ependymoma the most common etiology.

Case Report: We report the case of a woman with sensorineural hearing loss and cerebellar ataxia, diagnosed of superficial siderosis on brain MRI. Read More

View Article and Full-Text PDF
October 2020

Paraganglioma of the urinary bladder: Case report and literature review.

IJU Case Rep 2020 Sep 4;3(5):192-195. Epub 2020 Jul 4.

Department of Urology Kurume University School of Medicine Kurume Japan.

Introduction: Paraganglioma of the urinary bladder is a very rare disease accounting for 0.06% of all bladder tumors. Owing to their rarity and symptomatic variability, preoperative diagnosis is often difficult. Read More

View Article and Full-Text PDF
September 2020

Micturition syncope: a rare presentation of bladder paraganglioma.

BMJ Case Rep 2020 Sep 2;13(9). Epub 2020 Sep 2.

Internal Medicine, Christian Medical College, Vellore, Tamil Nadu, India.

A 68-year-old woman presented with episodes of headache, palpitations, sweating and poorly controlled hypertension for the past 6 years. These symptoms were, at times, associated with micturition, and there were few episodes of micturition syncope as well. She had elevated 24-hour urinary normetanephrine and was found to have a paraganglioma arising from the urinary bladder infiltrating the sigmoid colon. Read More

View Article and Full-Text PDF
September 2020

Diagnosis and treatment of a rare tumor-bladder paraganglioma.

Mol Clin Oncol 2020 Oct 11;13(4):40. Epub 2020 Aug 11.

Department of Urology, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST (Peking University, Hong Kong University of Science and Technology) Medical Center, Shenzhen, Guangdong 518036, P.R. China.

Bladder paragangliomas are very rare tumors that are often misdiagnosed. The present study retrospectively analyzed the clinical data and follow-up results of patients with bladder paraganglioma that were treated surgically in Peking University Shenzhen Hospital between 2012 and 2018, and reviewed the relevant literature. A total of 4 patients with bladder paraganglioma were treated surgically from 2012 to 2018. Read More

View Article and Full-Text PDF
October 2020

Editorial Comment to Combination of en bloc transurethral resection with laparoscopic partial cystectomy for paraganglioma of the bladder.

IJU Case Rep 2019 Sep 23;2(5):286-287. Epub 2019 Jul 23.

Department of Urology Tokyo Medical University Tokyo Japan.

View Article and Full-Text PDF
September 2019

Combination of en bloc transurethral resection with laparoscopic partial cystectomy for paraganglioma of the bladder.

IJU Case Rep 2019 Sep 4;2(5):283-286. Epub 2019 Jul 4.

Department of Urology The Jikei University School of Medicine Minato-ku Tokyo Japan.

Introduction: Paraganglioma of the bladder is an extremely rare tumor, and special attention should be paid to elevation of blood pressure during tumor resection.

Case Presentation: A 64-year-old woman presented with elevation of blood pressure during thoracic surgery. Multiparametric magnetic resonance imaging revealed a bladder tumor, and noradrenalin levels were elevated in plasma and urine. Read More

View Article and Full-Text PDF
September 2019

Aggressive Paraganglioma of the Urinary Bladder with Local Recurrence and Pelvic Metastasis.

Pathol Oncol Res 2020 Oct 17;26(4):2827-2829. Epub 2020 Jun 17.

Department of Urology, Stanford University Medical Center, Stanford, CA, USA.

Many pheochromocytoma and extra-adrenal paraganglioma are benign, but some are malignant. Pheochromocytoma of the Adrenal gland Scaled Score analyzed the histological characteristics of the tumor. Tumors with a Pheochromocytoma of the Adrenal gland Scaled Score of 4 or higher have a higher risk of recurrence. Read More

View Article and Full-Text PDF
October 2020

Rewired functional regulatory networks among miRNA isoforms (isomiRs) from let-7 and miR-10 gene families in cancer.

Comput Struct Biotechnol J 2020 13;18:1238-1248. Epub 2020 May 13.

Department of Bioinformatics, Smart Health Big Data Analysis and Location Services Engineering Lab of Jiangsu Province, School of Geographic and Biologic Information, Nanjing University of Posts and Telecommunications, Nanjing, China.

Classical microRNA (miRNA) has been so far believed as a single sequence, but it indeed contains multiple miRNA isoforms (isomiR) with various sequences and expression patterns. It is not clear whether these diverse isomiRs have potential relationships and whether they contribute to miRNA:mRNA interactions. Here, we aimed to reveal the potential evolutionary and functional relationships of multiple isomiRs based on let-7 and miR-10 gene families that are prone to clustering together on chromosomes. Read More

View Article and Full-Text PDF

Symptomatic paraganglioma of the urinary bladder: A rare case treated with a combined surgical approach.

Urol Case Rep 2020 Nov 29;33:101290. Epub 2020 May 29.

Erciyes University, Department of Urology, Kayseri, Turkey.

Pheochromocytomas are tumors of the embryonic chromaffin cells, originating from the embryonic neural crest. The pheochromocytomas developing at extra-adrenal locations are termed paragangliomas, which are extremely rare and account for almost 0.06% of all bladder tumors. Read More

View Article and Full-Text PDF
November 2020

Bladder Paraganglioma Mimicking a Tumor Contained in a Ureterocele.

Urology 2020 Aug 24;142:e36-e38. Epub 2020 May 24.

Department of Urology, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Republic of Korea. Electronic address:

Extra-adrenal pheochromocytoma is called paraganglioma. Paraganglioma near the ureterovesical junction can be confused with urothelial carcinoma in a ureterocele. Urinary metanephrine can be an indicator for bladder paraganglioma. Read More

View Article and Full-Text PDF

FDG Uptake in Brown Adipose Tissue Activated by a β3-Adrenergic Receptor Agonist Prescribed for Overactive Bladder.

Clin Nucl Med 2020 Aug;45(8):628-631

Diagnostic Radiology, Shiga General Hospital, Moriyama, Japan.

Brown adipose tissue (BAT), which produces energy and is known to play a role as a hibernating gland, is sometimes visualized on F-FDG PET in children or in slender young adults in a cold environment. Because BAT is activated by catecholamines, FDG uptake in BAT is also observed in patients with pheochromocytoma or paraganglioma. We present the case of an elderly woman with remarkable FDG uptake in BAT. Read More

View Article and Full-Text PDF

Bladder Paraganglioma.

J Belg Soc Radiol 2020 May 12;104(1):25. Epub 2020 May 12.

UZ Ghent, BE.

A submucosal bladder wall lesion with high signal on T2-weighted MRI warrants blood and urine analysis to rule out a paraganglioma. Read More

View Article and Full-Text PDF

Successful transurethral resection of the prostate in ectopic prostate pheochromocytoma: A case report.

Medicine (Baltimore) 2020 Apr;99(17):e19852

Department of Medicine, Lishui Municipal Central Hospital, Lishui, Zhejiang Province.

Introduction: Most pheochromocytomas of the urinary tract are located in the bladder. However, ectopic prostate pheochromocytomas have rarely been reported. We herein report an unusual case of ectopic prostate pheochromocytoma successfully treated by transurethral resection of the prostate (TURP). Read More

View Article and Full-Text PDF

The Diagnostic Dilemma of GATA3 Immunohistochemistry in Pheochromocytoma and Paraganglioma.

Endocr Pathol 2020 Jun;31(2):95-100

Department of Endocrinology, Metabolism, and Hypertension, National Hospital Organization, Kyoto Medical Center, Kyoto, Japan.

Although GATA3 has been recognized as a useful marker for mammary and urothelial carcinomas, there is large variation in GATA3 expression detected in pheochromocytoma (PC) and paraganglioma (PGL), from 90% to less than 5%. For GATA3 to be a useful diagnostic marker for PCCs/PGLs, the reasons for such discrepancy must be elucidated. Thus, we compared different immunohistochemistry protocols. Read More

View Article and Full-Text PDF