603 results match your criteria Paraganglioma of the Bladder


The extended posterior approach for resection of sacral tumours.

Eur Spine J 2018 Nov 20. Epub 2018 Nov 20.

Division of Spine Surgery, Department of Orthopaedics, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, 576-104, India.

Purpose: The conventional posterior approach is mostly advocated for excision of sacral tumours below S2. We describe an operative technique of single-stage en bloc resection of sacral tumours, extending up to S1, through an extended posterior approach.

Method: Nine patients, who had undergone resection of sacral tumours, by the described technique formed the basis of this study. Read More

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http://dx.doi.org/10.1007/s00586-018-5834-3DOI Listing
November 2018
22 Reads

Clinicopathological characteristics and survival outcomes of bladder neuroendocrine carcinomas: a population-based study.

Cancer Manag Res 2018 11;10:4479-4489. Epub 2018 Oct 11.

Department of Urology, Subei People's Hospital of Jiangsu Province (Clinical Medical College, Yangzhou University), Yangzhou, Jiangsu, People's Republic of China,

Background: Bladder neuroendocrine carcinomas (BNECs) are relatively a rare type of tumor. The aim of this study was to examine the clinicopathological characteristics and predictors of survival outcomes of patients with BNECs based on the analysis of the national Surveillance, Epidemiology, and End Results (SEER) database.

Materials And Methods: Kaplan-Meier analysis with log-rank test was used for survival comparisons. Read More

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https://www.dovepress.com/clinicopathological-characteristic
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http://dx.doi.org/10.2147/CMAR.S175286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190820PMC
October 2018
16 Reads

Imaging Characteristics of a Bladder Wall Paraganglioma.

Clin Nucl Med 2019 Jan;44(1):66-67

Division of Diagnostic Imaging, Department of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.

A 65-year-old man with a history of hypertension and nephrolithiasis presented with flank pain. Urographic CT demonstrated a 1.7-cm nodule arising from the bladder wall. Read More

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http://Insights.ovid.com/crossref?an=00003072-201901000-0001
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http://dx.doi.org/10.1097/RLU.0000000000002324DOI Listing
January 2019
8 Reads

Composite Paraganglioma: Pioneering in the Head and Neck.

Int J Surg Pathol 2018 Sep 16:1066896918799940. Epub 2018 Sep 16.

1 Yale University, New Haven, CT, USA.

Composite paragangliomas are rare with less than 20 cases documented in the abdomen, retroperitoneum, and urinary bladder. In this article, we report the first case of composite paraganglioma in the head and neck presenting as a soft tissue mass in the neck adjacent to the carotid artery in a 50-year-old woman. We discuss the clinicopathologic findings and genetic implications, and we review the literature of this rare entity. Read More

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http://dx.doi.org/10.1177/1066896918799940DOI Listing
September 2018
15 Reads

The Diagnosis and Clinical Significance of Paragangliomas in Unusual Locations.

J Clin Med 2018 Sep 13;7(9). Epub 2018 Sep 13.

Department of Pathology, University Health Network, Toronto, ON M5G 2C4, Canada.

Paragangliomas are neuroendocrine neoplasms, derived from paraganglia of the sympathetic and parasympathetic nervous systems. They are most commonly identified in the head and neck, being most frequent in the carotid body, followed by jugulotympanic paraganglia, vagal nerve and ganglion nodosum, as well as laryngeal paraganglia. Abdominal sites include the well-known urinary bladder tumors that originate in the Organ of Zuckerkandl. Read More

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http://www.mdpi.com/2077-0383/7/9/280
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http://dx.doi.org/10.3390/jcm7090280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162705PMC
September 2018
18 Reads

FDG-PET and CT findings of activated brown adipose tissue in a patient with paraganglioma.

Eur J Radiol Open 2018 22;5:126-130. Epub 2018 Aug 22.

Departments of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.

A 17-year-old female had been complaining of a headache for 6 years. She presented severe hypertension (200/138 mmHg) on admission. CT showed a hypervascular tumor behind the urinary bladder and a swelling of the right internal obturator node. Read More

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http://dx.doi.org/10.1016/j.ejro.2018.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106707PMC
August 2018
6 Reads

Germline mutations in children and adults with cancer.

Cold Spring Harb Mol Case Stud 2018 Aug 1;4(4). Epub 2018 Aug 1.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.

Mutations in succinate dehydrogenase complex genes predispose to familial paraganglioma-pheochromocytoma syndrome (FPG) and gastrointestinal stromal tumors (GIST). Here we describe cancer patients undergoing agnostic germline testing at Memorial Sloan Kettering Cancer Center and found to harbor germline mutations. Using targeted sequencing covering the cancer census genes, we identified 10 patients with germline mutations. Read More

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http://dx.doi.org/10.1101/mcs.a002584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071569PMC
August 2018
8 Reads

Treatment responses to antiangiogenetic therapy and chemotherapy in nonsecreting paraganglioma (PGL4) of urinary bladder with SDHB mutation: A case report.

Medicine (Baltimore) 2018 Jul;97(30):e10904

Endocrinology.

Introduction: Paraganglioma (PGL) is a rare neuroendocrine tumor. Currently, the malignancy is defined as the presence of metastatic spread at presentation or during follow-up. Several gene mutations are listed in the pathogenesis of PGL, among which succinate dehydrogenase (SDHX), particularly the SDHB isoform, is the main gene involved in malignancy. Read More

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http://dx.doi.org/10.1097/MD.0000000000010904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078645PMC
July 2018
4 Reads

Postmicturition syndrome: a neglected syndrome dangerous for the bladder and the heart.

J Am Soc Hypertens 2018 Aug 18;12(8):589-593. Epub 2018 Jun 18.

Cardiology Department, ASST Nord Milano, Ospedale E. Bassini, Cinisello Balsamo, Milano, Italy. Electronic address:

Postmicturition syndrome refers to symptoms caused by overdistension of the bladder or micturition. Bladder paraganglioma is a rare neuroendocrine neoplasm, which arises from the chromaffin tissue of the sympathetic nervous system embedded in the muscle layer of the bladder wall. Clinical presentation of catecholamine-secreting paragangliomas may mimic that of hyperfunctioning adrenal pheochromocytoma. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19331711183018
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http://dx.doi.org/10.1016/j.jash.2018.06.008DOI Listing
August 2018
10 Reads

68Ga-PSMA-HBED-CC-Avid Synchronous Urinary Bladder Paraganglioma in a Patient With Metastatic Prostate Carcinoma.

Clin Nucl Med 2018 Sep;43(9):e329-e330

Urology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.

Ga-PSMA-HBED-CC PET/CT has proven to be a useful modality in patients with prostate carcinoma, especially in those with suspected recurrence and in detection of locoregional and distant metastases. However, with expanding use of this tracer, several recent reports of in vivo expression of PSMA in nonprostatic benign and malignant entities have been published. We report a patient with PSMA-avid synchronous urinary bladder paraganglioma and metastatic prostate carcinoma. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002172DOI Listing
September 2018
5 Reads
3.931 Impact Factor

Partial Cystectomy of Paraganglioma of the Urinary Bladder Before Living Kidney Transplantation: Case Report.

Transplant Proc 2018 Apr;50(3):898-901

Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan; Department of Advanced Transplant and Regenerative Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.

Background: Paraganglioma (extra-adrenal pheochromocytoma) of the bladder is a very rare disease, accounting for 0.06% of all bladder tumors. Optimal management of bladder paraganglioma before kidney transplantation is unknown. Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.01.015DOI Listing
April 2018
7 Reads

Paraganglioma of Urinary Bladder Managed by Laparoscopic Partial Cystectomy in Conjunction with Flexible Cystoscopy: A Case Report.

J Endourol Case Rep 2018 1;4(1):15-17. Epub 2018 Feb 1.

Department of Urology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Paraganglioma of the urinary bladder (PUB) is exceedingly rare, accounting for <0.1% of all urinary bladder tumors. Various challenging treatment options are available. Read More

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http://dx.doi.org/10.1089/cren.2017.0132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820683PMC
February 2018
6 Reads

Minimally invasive partial cystectomy with bilateral vesico-ureteric junction resection and reimplantation for a large paraganglioma involving urinary bladder trigone.

Cent European J Urol 2017 19;70(4):378-381. Epub 2017 Sep 19.

Department of Urology, Leipzig University Hospital, Leipzig, Germany.

Paragangliomas are neuroendocrine tumours of extra adrenal origin. Although it occurs rarely in the genitourinary system, urinary bladder is the most common site. Its diagnosis warrants complete surgical excision with lymphadenectomy in case of metastatic disease. Read More

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http://dx.doi.org/10.5173/ceju.2017.1351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791395PMC
September 2017
10 Reads

Paraganglioma of the Urinary Bladder: A Rare Cause of Hypertension and Urinary Tract Infections.

Am J Med Sci 2018 Feb 8;355(2):191-194. Epub 2017 Apr 8.

University of Central Florida College of Medicine, Orlando, Florida; Orlando VA Medical Center, Orlando, Florida. Electronic address:

Pheochromocytoma is a neoplasm, which develops from cells of the chromaffin tissues that are derived from the ectodermic neural system and mostly situated within the adrenal medulla. Approximately 15% of pheochromocytoma cases arise from extra-adrenal chromaffin tissue. Pheochromocytoma of the bladder is rare and accounts for less than 0. Read More

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http://dx.doi.org/10.1016/j.amjms.2017.03.037DOI Listing
February 2018
6 Reads

Case - Bladder paraganglioma in a pediatric patient.

Can Urol Assoc J 2018 May 6;12(5):E260-E264. Epub 2018 Feb 6.

British Columbia Children's Hospital, Department of Urological Sciences; Vancouver, BC, Canada.

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http://dx.doi.org/10.5489/cuaj.4937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966941PMC
May 2018
32 Reads

[Analysis of clinical characteristics of paraganglioma in 42 patients].

Zhonghua Yi Xue Za Zhi 2018 Jan;98(4):280-283

Department of Endocrinology, Peking University First Hospital, Beijing 100034, China.

To summarize the clinical characteristics of paraganglioma. A total of 215 pheochromocytoma/ paraganglioma cases in Peking University First Hospital between January 1996 and December 2014 were retrospectively analyzed. The patients were divided into two groups according to the tumor position: pheochromacytoma group (173 patients) and paraganglioma group (42 patients). Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2018.04.008DOI Listing
January 2018
7 Reads

Anatomic Location Is the Primary Determinant of Survival for Paragangliomas.

Am Surg 2017 Oct;83(10):1132-1136

John Wayne Cancer Institute, Santa Monica, California, USA.

Paragangliomas (PGL) are rare neuroendocrine tumors. This study describes the largest collection of PGLs and evaluates factors that impact survival. Patients with PGL from 1998 to 2013 in the NCDB were reviewed. Read More

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October 2017
7 Reads

Pitfalls of Frozen Section Diagnosis for Paraganglioma: A Clinicopathologic Analysis and Review of the Literature.

Int J Surg Pathol 2018 May 23;26(3):213-220. Epub 2017 Nov 23.

3 Department of Pathololgy, Sungkyunkwan University, Seoul, Republic of Korea.

Few paraganglioma (PG) cases include frozen section diagnoses, and therefore, the accuracy of frozen section diagnosis for PG remains unknown. To better understand the histologic characteristics and pitfalls of frozen section findings for PG, 15 PG cases with frozen section diagnoses were selected from 12 articles through PubMed (1984-2015). In addition, we included 3 cases of PG for which intraoperative consultations were requested during a 5-year period (2012-2016) in 2 hospitals. Read More

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http://dx.doi.org/10.1177/1066896917742199DOI Listing
May 2018
33 Reads

Bladder wall paraganglioma located using I-mIBG SPECT and CT imaging.

Rev Esp Med Nucl Imagen Mol 2018 Jul - Aug;37(4):253-254. Epub 2017 Oct 27.

Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza Università di Roma, Roma, Italia.

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http://dx.doi.org/10.1016/j.remn.2017.07.008DOI Listing
October 2017
13 Reads

Paraganglioma in the bladder: a case report.

J Med Case Rep 2017 Oct 31;11(1):306. Epub 2017 Oct 31.

Division of Diagnostic Pathology, Yokohama City University Medical Center, Yokohama, Japan.

Background: Paraganglioma is an extra site of pheochromocytoma. Paraganglioma in the bladder is a very rare disease accounting for 0.06% of all bladder tumors. Read More

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http://dx.doi.org/10.1186/s13256-017-1473-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663097PMC
October 2017
11 Reads

Pheochromocytoma of the bladder.

JAAPA 2017 Oct;30(10):23-25

The authors practice at CHI Health Alegent Creighton Clinic Urology in Omaha, Neb. Dr. Siref also is program director of the urologic surgery residency program and an associate professor in the Section of Urologic Surgery at Creighton University School of Medicine in Omaha. Dr. Feloney also is chief of the Division of Urology and an associate professor in the Department of Surgery at Creighton University School of Medicine and practices at the VA Nebraska-Western Iowa Healthcare System. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Pheochromocytoma is a rare catecholamine-secreting tumor. Unless recognized and treated appropriately it can be lethal. Common symptoms include sustained or paroxysmal hypertension associated with headaches, sweating, or palpitations. Read More

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http://dx.doi.org/10.1097/01.JAA.0000522134.68445.50DOI Listing
October 2017
9 Reads

Spinal Metastasis of Unknown Primary Accompanied by Neurologic Deficit or Vertebral Instability.

World Neurosurg 2018 Jan 23;109:e33-e42. Epub 2017 Sep 23.

Department of Radiology, Yuzuncu Yil University Medical School, Van, Turkey.

Background And Objective: Spinal bone metastases are common. They are mostly localized to the lumbar, thoracic, and cervical spine. The most common primaries to result in spinal metastases include lung, breast, and prostate carcinomas in adults as opposed to leukemia, Ewing sarcoma, rhabdomyosarcoma, and neuroblastoma in children. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750173160
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http://dx.doi.org/10.1016/j.wneu.2017.09.099DOI Listing
January 2018
17 Reads

[A Case of Primary Schwannoma of the Urinary Bladder].

Hinyokika Kiyo 2017 Aug;63(8):323-328

The Department of Urology and Andrology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.

A 68-year-old woman presented with a bladder tumor. She was asymptomatic, and the tumor was incidentally detected with radiological imaging performed during treatment of cervical cancer. Magnetic resonance imaging and computed tomography revealed a solitary submucosal tumor located in the anterior wall of the urinary bladder, with homogeneous contrast enhancement. Read More

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http://dx.doi.org/10.14989/ActaUrolJap_63_8_323DOI Listing
August 2017
9 Reads

[Diagnosis and treatment experience of transurethral resection for paraganglioma of urinary bladder in 8 cases].

Zhonghua Yi Xue Za Zhi 2017 Jul;97(28):2205-2207

Department of Urology, Chinese PLA General Hospital, Beijing 100853, China.

To discuss the experience of diagnosis and treatment of transurethral resection of paraganglioma in urinary bladder. This retrospective study included 8 patients who underwent transurethral resection of paraganglioma in bladder from October 2009 to April 2015. Four males and 4 females were enrolled. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2017.28.010DOI Listing
July 2017
13 Reads

The Landscape of Whole-genome Alterations and Pathologic Features in Genitourinary Malignancies: An Analysis of the Cancer Genome Atlas.

Eur Urol Focus 2017 12 8;3(6):584-589. Epub 2017 Feb 8.

The James Buchanan Brady Urological Institute & Department of Urology, Johns Hopkins University School of Medicine.

Background: The accumulation of somatic genetic alterations drives carcinogenesis. Little is known, however, about how the level of genetic alteration across an entire cancer genome affects tumor grade, stage or survival.

Objective: To investigate the influence of somatic mutation count (MC) and copy number variation (CNV) on pathologic and oncologic outcomes in patients with genitourinary malignancies in The Cancer Genome Atlas (TCGA). Read More

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http://dx.doi.org/10.1016/j.euf.2017.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548653PMC
December 2017
18 Reads

Paravesical (urachal) paraganglioma (PGL) presenting as hypertensive crisis during micturition, mimicking bladder PGL.

J Formos Med Assoc 2018 03 21;117(3):247-249. Epub 2017 Jul 21.

Division of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jfma.2017.06.012DOI Listing
March 2018
12 Reads

Functioning metastatic paraganglioma of the urinary bladder in a 10-year-old child.

BMJ Case Rep 2017 Jul 19;2017. Epub 2017 Jul 19.

Department of Diagnostic Radiology, American University of Beirut Medical Center, Beirut, Lebanon.

Paragangliomas of the urinary bladder are very rare tumours representing less than 1% of bladder tumours. Preoperative diagnosis is essential to avoid perioperative complications related to catecholamine release. A high index of suspicion should be maintained when the classical symptoms of voiding-related paroxysms of headache, palpitation and dizziness are present. Read More

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http://dx.doi.org/10.1136/bcr-2017-220533DOI Listing
July 2017
7 Reads

Biodistribution and Dosimetry of F-Meta-Fluorobenzylguanidine: A First-in-Human PET/CT Imaging Study of Patients with Neuroendocrine Malignancies.

J Nucl Med 2018 Jan 13;59(1):147-153. Epub 2017 Jul 13.

Pediatric Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

I-meta-iodobenzylguanidine (I-MIBG) imaging is currently a mainstay in the evaluation of many neuroendocrine tumors, especially neuroblastoma. I-MIBG imaging has several limitations that can be overcome by the use of a PET agent. F-meta-fluorobenzylguanidine (F-MFBG) is a PET analog of MIBG that may allow for single-day, high-resolution quantitative imaging. Read More

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http://dx.doi.org/10.2967/jnumed.117.193169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750519PMC
January 2018
40 Reads

Paraganglioma of the Urinary Bladder: A Series of 22 Cases in a Single Center.

Clin Genitourin Cancer 2017 10 28;15(5):e765-e771. Epub 2017 Mar 28.

Department of Urology, State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/Chinese PLA Medical School, Beijing, P.R. China. Electronic address:

Objective: Paraganglioma of the urinary bladder (PUB) is rare in bladder cancer, and currently, a study examining large number of cases from a single center has not been reported. This study aimed to present the clinical features, treatments, pathological characteristics, and prognosis of PUB.

Patients And Methods: From January 2006 to June 2016, 22 patients were pathologically diagnosed with PUB in our hospital. Read More

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http://dx.doi.org/10.1016/j.clgc.2017.03.010DOI Listing
October 2017
28 Reads

Paraganglioma of the bladder in a kidney transplant recipient: A case report.

Mol Clin Oncol 2017 Apr 6;6(4):553-555. Epub 2017 Mar 6.

Department of Nephrology and Kidney Transplantation, Necker Enfants-Malades Hospital, Paris Descartes University, Assistance Publique-Hôpitaux de Paris, 75015 Paris, France.

Renal transplantation has been associated with a significantly increased risk of developing cancer, including bladder neoplasia, with urothelial carcinoma being the most frequent type of bladder cancer. Bladder paraganglioma, also referred to as extra-adrenal pheochromocytoma, is a rare but severe condition that may cause a severe hypertensive crisis during handling and mobilization of the tumor. We herein present the case of a 67-year-old kidney transplant recipient with a bladder polyp consistent with paraganglioma of the bladder. Read More

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http://dx.doi.org/10.3892/mco.2017.1182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374891PMC
April 2017
20 Reads

Genitourinary paraganglioma: Demographic, pathologic, and clinical characteristics in the surveillance, epidemiology, and end results database (2000-2012).

Urol Oncol 2017 07 18;35(7):457.e9-457.e14. Epub 2017 Mar 18.

Urologic Oncology Branch, National Cancer Institute, Bethesda, MD. Electronic address:

Background: Extra-adrenal paragangliomas (PGLs) are infrequent, benign, and neuroendocrine tumors arising from chromaffin cells of the autonomic nervous system. Most PGLs are sporadic, but up to 32% are associated with inherited syndromes such as neurofibromatosis type 1, von Hippel-Lindau disease, and familial PGL. Although most PGLs develop above the umbilicus, they have been reported in the genitourinary (GU) tract. Read More

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http://dx.doi.org/10.1016/j.urolonc.2017.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476479PMC
July 2017
10 Reads

MIBG Localization of a Subclinical Paraganglioma of the Bladder.

Clin Nucl Med 2017 Apr;42(4):e196-e198

From the Department of Radiology, University of Virginia Health System, Charlottesville, VA.

Urinary bladder paragangliomas are very rare, and the majority are hormonally active. Nonfunctioning paragangliomas are even rarer and more difficult to diagnose because of absence of catecholamine secretion. We present a 27-year-old woman with an asymptomatic paraganglioma of the urinary bladder discovered incidentally in a patient with prior resection of a functional pararenal paraganglioma. Read More

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http://dx.doi.org/10.1097/RLU.0000000000001562DOI Listing
April 2017
5 Reads

Pheochromocytoma: A Rare Presentation.

J Ark Med Soc 2017 Feb;113(8):188-190

Pheochromocytoma is a very rare neuroendocrine tumor usually located in one or both adrenal glands with an incidence of about 4 per 1,000,000 and about 1000 diagnosed per year. Pheochromocytomas can be located in extra-adrenal locations with about 1% being located in the urinary bladder.(1) We describe the presentation, diagnosis and treatment of one of these extremely rare tumors in the bladder. Read More

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February 2017
2 Reads

Urine cytology findings of primary paraganglioma of the urinary bladder: Case report.

Diagn Cytopathol 2017 Apr 22;45(4):350-353. Epub 2017 Jan 22.

Department of Urology, Ewha Womans University School of Medicine, Seoul, Korea.

Paraganglioma (PG) of the urinary bladder was detected in a 64-year-old male who was admitted to the hospital with gross hematuria. In voided urine, atypical cells were scattered as nests and single cells on low-power view. On higher-power view, tumor nests were composed of epithelioid cells with fine chromatin and moderate cytoplasm admixed with occasional spindle sustentacular cells. Read More

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http://dx.doi.org/10.1002/dc.23667DOI Listing
April 2017
6 Reads

Clinicopathologic Characteristics and Mutational Status of Succinate Dehydrogenase Genes in Paraganglioma of the Urinary Bladder: A Multi-Institutional Korean Study.

Arch Pathol Lab Med 2017 May 7;141(5):671-677. Epub 2016 Nov 7.

From the Department of Pathology, Ewha Womans University School of Medicine, Seoul, Korea (Drs S. Park, S.H. Sung, and M.S. Cho); the Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea (Drs Kang and G.Y. Kwon); the Department of Pathology, Ajou University School of Medicine, Suwon, Korea (Dr J.E. Kwon); the Department of Pathology, Yonsei University College of Medicine, Seoul, Korea (Dr S.K. Kim and N.H. Cho); the Department of Pathology, Inje University Haeundae Paik Hospital, Pusan, Korea (Dr J.Y. Kim); the Department of Pathology, Korea University School of Medicine, Seoul, Korea (Drs C.H. Kim and Chae); the Department of Pathology, Inje University Sanggye Paik Hospital, Seoul, Korea (Dr H.J. Kim); the Department of Pathology and Kidney Research Institute, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea (Dr Moon); the Department of Pathology, College of Medicine, Hanyang University Guri Hospital, Guri, Korea (Drs Pyo and Oh); the Department of Pathology, Pusan National University Hospital College of Medicine, Pusan, Korea (Dr W.Y. Park); the Department of Hospital Pathology, Incheon St Mary's Hospital, College of Medicine, Catholic University of Korea, Incheon, Korea (Dr E.S. Park); the Department of Pathology, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, Korea (Dr J.Y. Sung); the Department of Pathology, Konkuk University School of Medicine, Seoul, Korea (Dr S.E. Lee); the Department of Pathology, Dankook University College of Medicine, Cheonan, Korea (Dr W. Lee); the Department of Pathology, Dongguk University College of Medicine, Gyeonju, Korea (Dr J.I. Lee); the Department of Pathology, Inje University Busan Paik Hospital, Pusan, Korea (Dr Jung); the Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea (Drs Y.M. Cho and Huh); the Department of Pathology, Gachon University Gil Medical Center, Incheon, Korea (Dr H.Y. Cho); the Department of Pathology, Konyang University School of Medicine, Daejeon, Korea (Dr Cha); the Department of Pathology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Korea (Dr Choe); the Department of Hospital Pathology, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Korea (Dr Choi); and the Department of Pathology and Genomic Medicine, The Methodist Hospital and Weill Medical College of Cornell University, Houston, Texas (Dr Ro).

Context: - Because of the limited number of available primary bladder paraganglioma (PBPG) cases, the rates of succinate dehydrogenase (SDH) mutations and the clinicopathologic characteristics of SDH-deficient tumors have not been fully studied.

Objective: - To define the clinicopathologic and molecular characteristics of PBPGs.

Design: - A total of 52 PBPGs were collected retrospectively. Read More

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http://dx.doi.org/10.5858/arpa.2016-0403-OADOI Listing
May 2017
50 Reads

Variant histology in bladder cancer: how it should change the management in non-muscle invasive and muscle invasive disease?

Transl Androl Urol 2016 Oct;5(5):692-701

Department of Urology, University of Muenster Medical Center, Muenster, Germany; ; Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Bladder cancer (BC) is a frequent type of carcinoma with an estimated incidence of approximately 100,000 men and women each year in the European Union (EU) with an associated mortality of 30,000 of these patients. In more than 70% the disease is diagnosed in a non-muscle invasive stage with the chance of minimally invasive, local treatment only, which might be required repetitively due to high rate of recurrence. In contrast, muscle invasive or metastatic stages need multimodal treatment strategies including surgical treatment and chemotherapy (CTX) in neoadjuvant (NAC), adjuvant, or palliative settings. Read More

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http://dx.doi.org/10.21037/tau.2016.06.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071184PMC
October 2016
16 Reads

Clinical Significance of Quantitative 123I-MIBG SPECT/CT Analysis of Pheochromocytoma and Paraganglioma.

Clin Nucl Med 2016 Nov;41(11):e465-e472

From the Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Purpose: This retrospective study compared the diagnostic performances of quantitative versus visual analyses of I-MIBG scintigraphy in patients with suspected pheochromocytoma and paraganglioma (PPGL).

Materials And Methods: SPECT images were obtained 6 and/or 24 h after MIBG injection from 68 patients with clinically suspected PPGL, with attenuation correction by low-dose unenhanced CT. Planar images were also obtained at each time point. Read More

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http://dx.doi.org/10.1097/RLU.0000000000001334DOI Listing
November 2016
8 Reads

Succinate Dehydrogenase B (SDHB)-Associated Bladder Paragangliomas.

Clin Genitourin Cancer 2017 02 23;15(1):e131-e136. Epub 2016 Jun 23.

Department of Endocrinology, St Bartholomew's Hospital, West Smithfield, London, UK.

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http://dx.doi.org/10.1016/j.clgc.2016.06.006DOI Listing
February 2017
14 Reads

An unusual case of asymptomatic non-urothelial bladder tumour.

Int J Surg Case Rep 2016 14;27:18-20. Epub 2016 Jul 14.

Department of Urology, Kingston Hospital NHS Foundation Trust, United Kingdom. Electronic address:

Introduction: Non-urothelial tumours are rare and account for less than 5% of all bladder tumours. Bladder paragangliomas also known as extra-adrenal pheochromocytomas are of the non-urothelial subgroup. We present an unusual case of asymptomatic bladder paraganglioma. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612163024
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http://dx.doi.org/10.1016/j.ijscr.2016.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983148PMC
July 2016
15 Reads

Pheochromocytoma of the urinary bladder--A case report.

Vojnosanit Pregl 2016 Jun;73(6):584-7

Introduction: Pheochromocytoma of the urinary bladder is a rare tumor and presents less than 0.06% of all urinary bladder tumors.

Case Report: We presented a 49-year-old female patient with a history of daily paroxysmal hypertension accompanied with flushing of the face and upper chest, palpitations and excessive sweating prior to micturition. Read More

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June 2016
30 Reads

Urology pertinent neuroendocrine tumors: focusing on renal pelvis, bladder, prostate located sympathetic functional paragangliomas.

Authors:
C Alberti

G Chir 2016 Mar-Apr;37(2):55-60

Urology pertinent neuroendocrine neoplasias are more and more driving to research attractive contributions mainly as regards the urinary tract paragangliomas, besides the prostate cancer neuroendocrine differentiation. About such visceral sympathetic paragangliomas, a considerable attention is aroused by those concerning the renal pelvis, urinary bladder and, particularly, the prostate gland. Essential catecholamine/adrenergic signal-mediated pathophysiological implications and outlined diagnostic approaches are here taken into consideration. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938221PMC
February 2017
14 Reads

Neuroendocrine Tumors of the Urinary Bladder According to the 2016 World Health Organization Classification: Molecular and Clinical Characteristics.

Endocr Pathol 2016 Sep;27(3):188-99

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, 350 West 11th Street, IUHPL Room 4010, Indianapolis, IN, 46202, USA.

Neuroendocrine neoplasms of the urinary bladder are a rare type of tumor that account for a small percentage of urinary bladder neoplasms. These tumors of the urinary bladder range from well-differentiated neuroendocrine neoplasms (carcinoids) to the more aggressive subtypes such as small cell carcinoma. Despite the rarity of the neuroendocrine tumors of the bladder, there has been substantial investigation into the underlying genomic, molecular, and the cellular alterations within this group of neoplasms. Read More

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http://link.springer.com/10.1007/s12022-016-9444-5
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http://dx.doi.org/10.1007/s12022-016-9444-5DOI Listing
September 2016
35 Reads

Radiotherapy for urinary bladder pheochromocytoma with invasion of the prostate: A case report and literature review.

Mol Clin Oncol 2016 Jun 17;4(6):1060-1062. Epub 2016 Mar 17.

Department of Radiotherapy, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, Shandong 264000, P.R. China.

Malignant pheochromocytoma is a rare tumor, for which there is currently no effective therapy. Cytoreductive surgery is recommended to reduce tumor burden and relieve the symptoms of catecholamine excess, although complete eradication of the lesions is often not feasible. In patients with advanced disease, for whom surgical resection is not an option, systemic chemotherapy, radiotherapy and treatment with iodine-131-meta-iodobenzylguanidine may be used to achieve symptomatic relief. Read More

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http://dx.doi.org/10.3892/mco.2016.820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888043PMC
June 2016
14 Reads

Urinary Bladder Paragangliomas: Analysis of Succinate Dehydrogenase and Outcome.

Endocr Pathol 2016 Sep;27(3):243-52

Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

Paragangliomas of the urinary bladder can arise sporadically or as a part of hereditary syndromes including those with underlying mutations in the succinate dehydrogenase (SDH) genes, which serve as tumor suppressors. SDH deficiency can be screened for by absence of immunohistochemical detection of SDHB. In this study of 11 cases, clinical follow-up was available for 9/11 cases. Read More

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http://dx.doi.org/10.1007/s12022-016-9439-2DOI Listing
September 2016
11 Reads

Pheochromocytoma of the Urinary Bladder - A Case Report of an Unusual Presentation.

Indian J Surg Oncol 2015 Sep 2;6(3):303-6. Epub 2015 Jul 2.

PG Department of Biotechnology & Microbiology, Karnatak University, Dharwad, 580003 India.

Urinary bladder pheochromocytoma is rare. We report a case of bladder pheochromocytoma presenting with practically no obvious clinical symptoms in an adolescent who had undergone repair of mitral valve disease. Read More

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http://dx.doi.org/10.1007/s13193-015-0430-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856671PMC
September 2015
10 Reads