13,552 results match your criteria Paracentesis


Permanent peritoneal ports for the management of recurrent malignant ascites: a retrospective review of safety and efficacy.

Intern Med J 2018 Dec;48(12):1524-1528

Palliative Care Services, Counties Manukau District Health Board, Middlemore Hospital, Auckland, New Zealand.

Large volume paracentesis is effective in relieving the symptoms of malignant ascites, but frequent procedures are often required. Permanent peritoneal ports are an alternative to repeated procedures. We describe our experience with the use of peritoneal ports in patients at Middlemore Hospital (Auckland, New Zealand) who had a port inserted for the drainage of malignant ascites. Read More

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December 2018
4 Reads

Usefulness of bioelectrical impedance analysis for monitoring patients with refractory ascites.

Rev Esp Enferm Dig 2018 Dec 4;111. Epub 2018 Dec 4.

UCG Digestive Diseases and CIBEREHD, Hospital Universitario de Valme Spain , Spain.

Background: bioelectrical impedance analysis is a technique for the determination of the hydropic component. The hydropic component, determined by blood volume, could be a reflection of the hemodynamic situation. This study aimed to evaluate the usefulness of peripheral bioelectrical impedance analysis (BIA) for the prediction of hemodynamic changes in large-volume paracentesis and prognosis. Read More

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December 2018
1 Read

Aggressive nutrition intervention reduces ascites and frequency of paracentesis in malnourished patients with cirrhosis and ascites.

JGH Open 2017 Nov 31;1(3):92-97. Epub 2017 Oct 31.

Liver Injury and Cancer Centenary Research Institute Sydney New South Wales Australia.

Background And Aim: Alterations in nutrient metabolism, nutritional requirements, and reduced dietary intakes are common in chronic liver disease (CLD). These result in malnutrition, sarcopenia, and exacerbate progression to decompensation and ascites. We aimed to investigate the effects of continuous tube feeding (TF) on nutritional status and levels of ascites in malnourished individuals with decompensated cirrhosis. Read More

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November 2017

Bilateral Phacomatosis Pigmentovascularis in a Young Male with Developmental Glaucoma and Varicose Veins.

J Curr Glaucoma Pract 2018 May-Aug;12(2):94-98. Epub 2018 Aug 1.

Senior Resident, Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India.

Aim: To report a case of bilateral phacomatosis pigmentovascularis (PPV), in a young male,presenting with developmental glaucoma and high myopia along with systemic features of klippel trenanauy weber (KTW) syndrome.

Background: The co-existence of oculodermal melanocytosis (ODM)and port-wine stain was termed PPV by Ota. Port-wine stain presents as part of Sturge-Weber syndrome (SWS). Read More

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August 2018
3 Reads

The Effect of Anti-Vascular Endothelial Growth Factor Agents on Intraocular Pressure and Glaucoma A Report by the American Academy of Ophthalmology.

Ophthalmology 2018 Nov 22. Epub 2018 Nov 22.

Harvard Medical School, Department of Ophthalmology, Massachusetts Eye & Ear Infirmary, Glaucoma Service, Boston, Massachusetts.

Purpose: To assess the effect of intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) agents on immediate and long-term intraocular pressure (IOP) elevation and glaucoma.

Methods: Literature searches of the PubMed and Cochrane databases, last conducted in April 2018, yielded 253 unique citations. Of these, 41 met the inclusion criteria and were rated according to the strength of evidence. Read More

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November 2018
5 Reads

Simulated training program in abdominal paracentesis for undergraduate medical students.

Gastroenterol Hepatol 2018 Nov 21. Epub 2018 Nov 21.

Departamento de Ciencias de la Salud, Facultad de Medicina, Pontificia Universidad Católica de Chile, Chile; Departamento de Gastroenterología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Chile; Centro de Educación Médica, Escuela de Medicina, Pontificia Universidad Católica de Chile, Chile. Electronic address:

Background And Aims: Abdominal paracentesis is an area that every general physician should know about, and the current learning model is unsafe for patients. Simulation allows students to develop their skills prior to clinical confrontation with minimal risks. The aims of this study were to design and evaluate a paracentesis simulation workshop for undergraduate students. Read More

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November 2018
4 Reads

Acute primary angle closure-treatment strategies, evidences and economical considerations.

Eye (Lond) 2018 Nov 22. Epub 2018 Nov 22.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China.

Acute primary angle closure requires emergency management that involves a rapid lowering of the intraocular pressure and resolution of relative pupil block - the most common mechanism of angle closure. Emergency strategies for lowering intraocular pressure include medical treatment and argon laser peripheral iridoplasty. Anterior chamber paracentesis and diode laser transcleral cyclophotocoagulation may be considered in special situations. Read More

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November 2018
5 Reads

Albumin: The Cons.

Authors:
Alastair O'Brien

Liver Transpl 2018 Nov 17. Epub 2018 Nov 17.

Institute of Liver Disease and Digestive Health, University College London, UK.

Intravenous albumin infusions have long been considered an important option in the treatment of patients with cirrhosis and ascites . Many studies have shown that 20% Human Albumin Solution (HAS) improves circulatory function and it is therefore recommended in international guidelines worldwide for use in hepatorenal syndrome (HRS), spontaneous bacterial peritonitis (SBP), as well as in preventing post paracentesis circulatory dysfunction following large volume paracentesis (LVP) . Albumin has also been reported to have beneficial immunomodulatory and endothelial effects and therefore may have a particular beneficial role in sepsis . Read More

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November 2018
4 Reads

Clinical characteristics and prognosis of serous body cavity effusions in patients with sepsis: a retrospective observational study.

BMC Anesthesiol 2018 Nov 14;18(1):169. Epub 2018 Nov 14.

Department of Emergency Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, People's Republic of China.

Background: Cavity effusion is common in patients with infectious diseases. However, the incidence rate and characteristics of serous cavity effusions (SCE) in septic patients are not clear to date. The objective of this study was to investigate the incidence and characteristics of SCE in septic patients and to explore the correlations between the bloody effusions and the illness severity/prognosis in septic patients. Read More

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November 2018
7 Reads

A Challenging Diagnosis of Ascites: A Case Report of Peritoneal Tuberculosis.

Case Rep Infect Dis 2018 23;2018:8136476. Epub 2018 Oct 23.

University of Florida-COM, Division of Internal Medicine, Jacksonville, FL, USA.

Approximately 2 billion people, which is about one third of the world's population, are infected with tuberculosis (TB). Around 10% of infected people will develop active TB at one point in their lifetime. We present a rare case of a 68-year-old male who presented to the emergency department with a 2-week progressive dyspnea. Read More

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October 2018
3 Reads

Bilateral central retinal artery occlusion from catastrophic antiphospholipid syndrome.

BMJ Case Rep 2018 Nov 12;2018. Epub 2018 Nov 12.

Department of Internal Medicine, John H Stroger Jr Hospital of Cook County, Chicago, Illinois, USA.

A 23-year-old woman with history of systemic lupus erythematous presented with dizziness and headache and was admitted for the stroke workup. During her stay, she had sudden painless loss of vision in her right eye consistent with central retinal artery occlusion (CRAO). Ocular massage and paracentesis were attempted without success to resume the flow. Read More

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November 2018
6 Reads

Ambulatory Fontan pressure monitoring: Results from the implantable hemodynamic monitor Fontan feasibility cohort (IHM-FFC).

Int J Cardiol 2018 Oct 28. Epub 2018 Oct 28.

The Ohio State University Wexner Medical Center, Department of Internal Medicine, Division of Cardiovascular Medicine, Columbus, OH, United States of America; Nationwide Children's Hospital, Department of Pediatrics, Division of Cardiovascular Medicine, Columbus, OH, United States of America.

Background: Implantable invasive hemodynamic monitoring (IHM) using the CardioMEMS™ HF system has been shown to reduce heart failure (HF) hospitalizations. IHMs have not yet been used in congenital heart disease (CHD). We aimed to evaluate feasibility and mid-term outcomes of IHM use in the single ventricle/Fontan population. Read More

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October 2018
6 Reads

Recurrent, late-onset pleural effusions in elderly patients receiving pacemaker therapy.

Medicine (Baltimore) 2018 Oct;97(43):e12915

Division of Respiratory Disease, Renmin Hospital of Wuhan University, Wuhan, China.

Late-onset pacemaker-related pleural effusions (PEs) are rare and are often misdiagnosed with other entities. Our study aimed to detail the clinical features and management of PEs long after pacemaker insertion.We conducted a review of 6 consecutive elderly patients with PEs, who had undergone a new pacemaker insertion from September 2014 to January 2017. Read More

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October 2018
2 Reads

Spontaneous Bacterial Peritonitis in Afebrile Cirrhotic Patients; Report from a Referral Transplantation Center.

Bull Emerg Trauma 2018 Oct;6(4):363-366

Department of Emergency Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Spontaneous bacterial peritonitis (SBP) is a complication of liver cirrhosis with adverse effect on patient prognosis. Early diagnosis and treatment is highly important, especially in patients without remarkable manifestations. We designed this study to determine the prevalence of SBP among afebrile cirrhotic patients and identify high-risk subgroups in a referral center in southern Iran. Read More

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October 2018
2 Reads

"Chylous Ascites: Complication of laparoscopic donor nephrectomy. Case Report and review of literature."

Transplantation 2018 Nov 5. Epub 2018 Nov 5.

Department of Renal Transplant Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: Chylous ascites (CA) is an extremely rare complication after laparoscopic donor nephrectomy (LDN). It can increase the hospital stay, morbidity in postoperative period and thus negating the benefits of laparoscopic surgery. Most of the cases were managed conservatively, but surgical intervention may be occasionally required. Read More

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November 2018
3 Reads

Cost-Effectiveness of Transjugular Intrahepatic Portosystemic Shunt versus Large-Volume Paracentesis in Refractory Ascites: Results of a Markov Model Incorporating Individual Patient-Level Meta-Analysis and Nationally Representative Cost Data.

J Vasc Interv Radiol 2018 Dec 2;29(12):1705-1712. Epub 2018 Nov 2.

Department of Interventional Radiology, University of Washington Medical Center, 1959 NE Pacific Street, Seattle, WA 98195.

Purpose: To compare relative cost-effectiveness of serial large-volume paracentesis (LVP) and transjugular intrahepatic portosystemic shunt (TIPS) creation for treatment of refractory ascites.

Materials And Methods: A decisional Markov model was developed to estimate payer cost and quality-adjusted life-ears (QALYs) associated with LVP and TIPS treatment strategies for cirrhotic patients with refractory ascites. Survival estimates were derived from an individual patient-level meta-analysis of prospective randomized clinical trials. Read More

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December 2018
6 Reads

Transjugular Intrahepatic Portosystemic Shunt for the Treatment of Portal Hypertension-Induced Refractory Ascites Due to Metastatic Carcinomatous Liver Disease.

J Vasc Interv Radiol 2018 Dec 2;29(12):1713-1716. Epub 2018 Nov 2.

Department of Radiology, University Hospitals Leuven, Herestraat 49, B-3000 Leuven, Belgium. Electronic address:

Three patients with a medical history of breast carcinoma and metastatic carcinomatous liver disease associated with severe portal hypertension and refractory ascites are presented. Transjugular intrahepatic portosystemic shunt creation was considered as a palliative treatment option and a valuable alternative to regular paracenteses in these patients. In 2 of the 3 patients, the refractory ascites was controlled for several months without need for paracentesis, and subsequently transjugular intrahepatic portosystemic shunt may provide valuable palliation and ascites control in patients with refractory ascites due to breast cancer-induced pseudocirrhosis. Read More

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December 2018
3 Reads

Topical Ganciclovir for Prophylaxis of Cytomegalovirus Endotheliitis in Endothelial Keratoplasty.

Cornea 2019 Jan;38(1):120-122

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.

Purpose: To describe the presentation and management of 2 cases of Descemet stripping automated endothelial keratoplasty (DSAEK) with failure secondary to cytomegalovirus (CMV) infection and prophylaxis with topical ganciclovir to prevent repeat failure of Descemet membrane endothelial keratoplasty (DMEK) regrafts.

Methods: A retrospective chart review was conducted for 2 patients with DSAEK failure secondary to CMV infection.

Results: A 70-year-old immunocompetent man (case 1) and a 53-year-old immunocompromised man (case 2) received DSAEK for presumed pseudophakic bullous keratopathy and endothelial decompensation secondary to recurrent uveitis, respectively. Read More

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January 2019
3 Reads

[Paracentesis as abdominal decompression therapy in neuroblastoma MS with massive hepatomegaly].

Cir Pediatr 2018 Oct 17;31(4):196-199. Epub 2018 Oct 17.

Servicio Cirugía Pediátrica. Hospital de Cruces. Baracaldo (Vizcaya).

Neuroblastoma MS with massive hepatomegaly is a small percentage of cases of neuroblastoma. It is more common in infants less than 4-6 weeks of life, and involves, in contrast to the standard of the NB MS, poor prognosis given the complications that can have. In the case of abdominal compartment syndrome it is recommended a quick start of chemotherapy, associating or not radiation therapy, to try to reduce the size of the liver, and if necessary, decompressive laparotomy. Read More

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October 2018
6 Reads

Hemodynamic Effects of Paracentesis in a Patient With a Fontan Circulation.

World J Pediatr Congenit Heart Surg 2018 Oct 24:2150135118779351. Epub 2018 Oct 24.

1 Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Recurrent ascites is a common manifestation of failing Fontan circulation. We present the hemodynamic response to large-volume paracentesis in a patient with Fontan circulation and Fontan-associated liver disease, documenting an immediate and substantial decline in systemic venous pressure and increase in cardiac output. These preliminary observations may have implications for the management of ascites in adults with Fontan circulation. Read More

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October 2018
1 Read

Ascites Index - an attempt to objectify the assessment of ascites.

J Ultrason 2018 ;18(73):140-147

3rd Department of Gynecology, Medical University of Lublin, Lublin, Poland.

Introduction: Ascites is observed in cancer patients as well as in other non-neoplastic processes. In some patients, it may cause severe symptoms that can become directly life-threatening. The assessment of the degree of ascites seems useful in the determination of treatment effects as well as in the monitoring of fluid accumulation and early planning of decompression procedures. Read More

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January 2018
3 Reads

Secondary bacterial peritonitis and pelvic abscess due to .

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Department of Infectious Disease, Mayo Clinic, Rochester, Minnesota, USA.

A 70-year-old man with a history of hepatic cirrhosis presented with abdominal discomfort and distention. Physical examination revealed abdominal distention, positive fluid wave and abdominal tenderness. Due to concerns for spontaneous bacterial peritonitis (SBP), paracentesis was performed. Read More

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October 2018
7 Reads

Neonate with urinary ascites but no hydronephrosis: unusual presentation of posterior urethral valves.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Pediatric Critical Care, Inova Children's Hospital, Falls Church, Virginia, USA.

Posterior urethral valves (PUV) are an important cause of paediatric obstructive uropathy. PUV are usually diagnosed by prenatal ultrasonography (US) revealing hydronephrosis and bladder distention. We describe a 17-day-old male infant with abdominal distention who had no hydronephrosis on prenatal US. Read More

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October 2018
8 Reads

Oral midodrine is comparable to albumin infusion in cirrhotic patients with refractory ascites undergoing large-volume paracentesis: results of a pilot study.

Eur J Gastroenterol Hepatol 2018 Oct 11. Epub 2018 Oct 11.

Department Hepatology, Theodor Bilharz Research Institute, Cairo, Egypt.

Background And Aims: Albumin infusion reduces the incidence of postparacentesis circulatory dysfunction among patients with cirrhosis and tense ascites compared with no treatment. Less costly treatment alternatives such as vasoconstrictors have been investigated, but the results are controversial. Midodrine, an oral α1-adrenergic agonist, increases effective circulating blood volume and renal perfusion by increasing systemic and splanchnic blood pressure. Read More

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October 2018
1 Read

Ascites with hepatic extravasation of total parenteral nutrition (TPN) secondary to umbilical venous catheter (UVC) malposition in an extremely preterm baby.

BMJ Case Rep 2018 Oct 8;2018. Epub 2018 Oct 8.

Division of Neonatology, Department of Pediatrics, Regina General Hospital, Regina, Saskatchewan, Canada.

The ease of access and advantages of a secure central line makes use of umbilical venous catheter (UVC) and umbilical artery catheters a part of the standard of care in the extremely premature babies in the neonatal intensive care unit. However, there are complications associated with their use. One of the uncommon complications reported is total parenteral nutrition (TPN) ascites secondary to vessel perforation or hepatic erosion by the tip of the catheter due to malposition of a UVC. Read More

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October 2018
2 Reads

Effect of NSAIDs on Pupil Diameter and Expression of Aqueous Humor Cytokines in FLACS Versus Conventional Phacoemulsification.

J Refract Surg 2018 Oct;34(10):646-652

Purpose: To compare the concentrations of interleukin (IL) (IL-1b, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70), interferon (IFN)-γ, tumor necrosis factor (TNF)-α, and TNF-β in the aqueous humor of patients undergoing femtosecond laser-assisted cataract surgery (FLACS) and corneal mechanical paracentesis treated with two different topical nonsteroidal anti-inflammatory drugs (NSAIDs): bromfenac and indomethacin.

Methods: In this prospective, randomized controlled, single-center study, aqueous humor samples were obtained immediately after performing the femtosecond laser procedure or at the start of conventional phacoemulsification. Preoperatively, the FLACS groups were administered (once daily and four times daily, respectively) either topical bromfenac 0. Read More

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October 2018
2 Reads
3.470 Impact Factor

Routine analysis of ascitic fluid for evidence of infection in children with chronic liver disease: Is it mandatory?

PLoS One 2018 5;13(10):e0203808. Epub 2018 Oct 5.

Pediatric Hepatology Unit, Pediatrics Department, Kasr Alainy School of Medicine, Cairo, Egypt.

Ascitic fluid infection is a major cause of morbidity and mortality in cirrhotic patients, requiring early diagnosis and therapy. We aimed to determine predictors of ascitic fluid infection in children with chronic liver disease. The study included 45 children with chronic liver disease and ascites who underwent 66 paracentesis procedures. Read More

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October 2018
7 Reads

Non-Self-Sealing (Leaky) Anterior Chamber Paracentesis: A New Technique in Managing Postphacoemulsification Intraocular Pressure Rise in Glaucoma and Normal Eyes.

Asia Pac J Ophthalmol (Phila) 2018 Sep-Oct;7(5):284-287. Epub 2018 Sep 26.

Sankara Nethralaya, Chennai, India.

Phacoemulsification (phaco) for cataract extraction is 1 of the most commonly performed ophthalmic surgeries. With increasing evidence of significant intraocular pressure (IOP) reduction after phaco, the paradigm for glaucoma treatment has been shifting toward more cataract extraction instead of glaucoma surgery; thus, the population of glaucoma patients undergoing phaco is likely to continue to increase in the coming years. Although the safety of surgery has improved over the years with newer technologies and machines, postoperative IOP spike remains an important condition even after an uneventful operation. Read More

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October 2018
1 Read

Association Between Type 2 Diabetes Mellitus, HbA1c and the Risk for Spontaneous Bacterial Peritonitis in Patients with Decompensated Liver Cirrhosis and Ascites.

Clin Transl Gastroenterol 2018 Sep 24;9(9):189. Epub 2018 Sep 24.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Carl-Neuberg-Str.1, 30625, Hannover, Germany.

Introduction: Type 2 diabetes mellitus (DM) is a frequent comorbidity among patients with liver cirrhosis. However, data regarding the impact of DM on spontaneous bacterial peritonitis (SBP) are quite limited. Our aim was to analyze the impact of DM and HbA1c values on the incidence of SBP and mortality in patients with liver cirrhosis and ascites. Read More

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September 2018
7 Reads

Point of care ultrasound training for internal medicine: a Canadian multi-centre learner needs assessment study.

BMC Med Educ 2018 Sep 20;18(1):217. Epub 2018 Sep 20.

Department of Medicine, University of Calgary, Calgary, AB, Canada.

Background: Significant gaps currently exist in the Canadian internal medicine point-of-care ultrasound (POCUS) curriculum. From a learner's perspective, it remains unknown what key POCUS skills should be prioritized. This needs assessment study seeks to establish educational priorities for POCUS for internal medicine residents at five Canadian residency training programs. Read More

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September 2018
6 Reads

EFFECT OF SERIAL ANTERIOR CHAMBER PARACENTESIS ON SUSTAINED INTRAOCULAR PRESSURE ELEVATION IN PATIENTS RECEIVING INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY.

Retina 2018 Sep 17. Epub 2018 Sep 17.

Department of Ophthalmology, University of Cincinnati, Cincinnati, Ohio.

Purpose: To investigate the effect of serial anterior chamber (AC) paracenteses in eyes with sustained elevations of intraocular pressure (IOP) in the setting of repeated intravitreal injections (IVI) of anti-vascular endothelial growth factor medications.

Methods: This is a retrospective records review of patients undergoing IVI of anti-vascular endothelial growth factor medication (bevacizumab, ranubizumab, or aflibercept), who demonstrated a sustained elevation of preinjection IOP and also received AC paracentesis immediately after IVI on at least three consecutive visits. Changes in preinjection IOP and cup-to-disk (C:D) ratio were compared before and after the initiation of IVI and before and after the introduction of AC paracenteses with each subsequent IVI. Read More

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September 2018
1 Read

Bleeding after paracentesis in patients with decompensated cirrhosis and acute kidney injury: The perfect storm.

Liver Int 2018 Nov 8;38(11):2101. Epub 2018 Oct 8.

Gastroenterology Unit, Department of Internal Medicine, Ospedale Policlinico San Martino-IRCCS per l'Oncologia, University of Genoa, Genoa, Italy.

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November 2018
2 Reads

Descemetorhexis Without Endothelial Keratoplasty Versus DMEK for Treatment of Fuchs Endothelial Corneal Dystrophy.

Cornea 2018 Dec;37(12):1479-1483

Department of Ophthalmology, University of Pittsburgh School of Medicine UPMC Eye Center, Pittsburgh, PA.

Purpose: To compare the visual outcomes and associated morbidity of patients with Fuchs endothelial corneal dystrophy who were treated with either Descemet membrane endothelial keratoplasty (DMEK) or descemetorhexis without endothelial keratoplasty (DWEK).

Methods: This is a retrospective comparative cohort study of 27 eyes with mild to moderate Fuchs dystrophy (with corneal guttae/edema limited to the central cornea with relatively clear periphery) that were treated at the University of Pittsburgh Medical Center from 2015 to 2017 with either DMEK (n = 15) or DWEK (n = 12). Descemetorhexis was performed by removing the central 4 mm of diseased Descemet membrane at the end of phacoemulsification for cataract surgery. Read More

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December 2018
3 Reads

Validation of Risk Score in Predicting Early Readmissions in Decompensated Cirrhotic patients: A Model Based on the Administrative Database.

Hepatology 2018 Sep 15. Epub 2018 Sep 15.

Division of gastroenterology Department of Internal Medicine, University of South Carolina School of Medicine, Columbia, SC.

Introduction: The early readmission in patients with decompensated liver cirrhosis leads to enormous burden on healthcare utilization.

Methods: Retrospective cohort study using the 2013 and 2014 Nationwide Readmission Database (NRD) was conducted. Patients with diagnoses of cirrhosis and at least one feature of decompensation were included. Read More

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September 2018
11 Reads

Albumin Utilization Evaluation in a Major Teaching Hospital in Iran: Recommendations for Guideline Development.

J Res Pharm Pract 2018 Jul-Sep;7(3):157-163

Department of Pharmacy, Firoozgar Hospital, Hospital Pharmacy Management (Madad Iran Holding), Iran University of Medical Sciences, Tehran, Iran.

Objective: Human albumin solution is an expensive colloidal preparation which is commonly used in clinical practice. Due to high cost of albumin, increased rate of the inappropriate use worldwide, and many other reasons, it is imperative to establish a practical protocol to use albumin products and limit its usage. The aim of this study was to identify albumin utilization patterns in a teaching hospital and to demonstrate the importance of the need to reconsider prescribing strategies for albumin administration. Read More

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September 2018
1 Read

Utility of amniotic fluid chitotriosidase in the prenatal diagnosis of lysosomal storage disorders.

Clin Biochem 2018 Nov 8;61:40-44. Epub 2018 Sep 8.

Sandor Lifesciences Pvt. Ltd, Hyderabad, India. Electronic address:

Objective: Plasma chitotriosidase is a documented biomarker for certain lysosomal storage disorders. However, its clinical utility for prenatal samples is not elucidated yet.

Methods: We have established Reference intervals for amniotic fluid chitotriosidase using control amniotic fluids (n = 47) and compared the activity with amniotic fluids affected by lysosomal storage disorders (n = 25). Read More

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November 2018
5 Reads

MYD88 L265P MUTATION DETECTION IN THE AQUEOUS HUMOR OF PATIENTS WITH VITREORETINAL LYMPHOMA.

Retina 2018 Sep 7. Epub 2018 Sep 7.

Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, University Vita-Salute, Milan, Italy.

Purpose: To detect the presence of MYD88 L265P mutation in the aqueous humor of patients with cytologically proven vitreoretinal lymphoma.

Methods: Eight consecutive patients with bilateral vitreoretinal lymphoma (16 eyes) were prospectively evaluated. Genomic DNA was extracted from aqueous samples after paracentesis and vitreous humor samples after diagnostic vitrectomy. Read More

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September 2018
1 Read

Chronic ocular hypertension in rabbits induced by limbal buckling.

Br J Ophthalmol 2018 Sep 8. Epub 2018 Sep 8.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China

Aim: To establish a rabbit model of chronic ocular hypertension (OHT) by limbal buckling.

Methods: Eighteen New Zealand White rabbits were involved and divided into three groups. A latex encircling band of 20, 25 or 35 mm was implanted behind the limbus in the right eye of each animal. Read More

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September 2018
3 Reads

Detection of EGFR T790M in a Large Amount of Malignant Ascites Cellblock.

Gan To Kagaku Ryoho 2018 08;45(8):1185-1187

Dept. of Respiratory Medicine,Tokyo Saiseikai Central Hospital.

Osimertinib is a highly active agent for patients with progression of lung cancer despite epidermal growth factor receptor (EGFR)tyrosine kinase inhibitor treatment. This resistance is usually due to EGFR exon 20 T790M mutation, which can be detected by repeat biopsy. We report a case in which EGFR exon 20 T790M mutation was detected by repeat ascitic fluid examination. Read More

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August 2018
5 Reads

Comparison of culture and real-time polymerase chain reaction methods for detection of in amniotic fluids samples.

Niger J Clin Pract 2018 Sep;21(9):1127-1131

Department of Medical Microbiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Background: Mycoplasma hominis is often present in the amniotic cavity with microbial invasion associated with spontaneous preterm labor. Conventional culture method is the gold standard for detection of Mycoplasmas, but real-time polymerase chain reaction (real-time PCR) has revolutionized the diagnosis of M. hominis. Read More

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September 2018
7 Reads

[Undergraduate student's perception of clinical simulation workshops: assessment of an instrument].

Rev Med Chil 2018 Jun;146(6):786-795

Departamento de Ciencias de la Salud, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Background: Simulation is a useful training tool for undergraduate medical students. A valid instrument is needed to assess students' perception of simulation workshops.

Aim: To adapt and validate an instrument to assess the undergraduate medical student's perception of simulation workshops of clinical procedures. Read More

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June 2018
2 Reads

Presumed Tuberculous Sclerokeratitis Presenting with Hypopyon.

Ocul Immunol Inflamm 2018 Aug 27:1-3. Epub 2018 Aug 27.

a Medical and Vision Research Foundations , Sankara Nethralaya , Chennai , India.

Purpose: To describe a case of presumed tuberculous sclerokeratitis which presented with anterior uveitis and hypopyon Methods: A retrospective chart review Results: A 23-year-old female presented with nodular scleritis, peripheral corneal opacities, and severe anterior chamber reaction with hypopyon. Her Mantoux test and interferon gamma release assay were positive and high-resolution computerized tomography of chest revealed right hilar lymphadenopathy. Aqueous aspirate from anterior chamber paracentesis of her right eye was negative for Mycobacterium tuberculosis genome. Read More

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August 2018
7 Reads

[Spontaneous Bacterial Peritonitis].

Authors:
Do Seon Song

Korean J Gastroenterol 2018 Aug;72(2):56-63

Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.

Spontaneous bacterial peritonitis (SBP) is defined as bacterial infections that occur in patients with cirrhosis and ascites without any significant intraperitoneal infection, accounting for approximately 10-30% of bacterial infections in hospitalized patients. SBP develops in patients with liver cirrhosis because bacterial translocations are increased by changes in the intestinal bacteria and mucosal barriers. In addition, the decreased host immune response cannot remove the bacteria and their products. Read More

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August 2018
9 Reads

[Ascites].

Authors:
Soung Won Jeong

Korean J Gastroenterol 2018 Aug;72(2):49-55

Department of Internal Medicine, Soonchunhyang University Hospital Seoul, Soonchunhyang University College of Medicine, Seoul, Korea.

Ascites is the most common cause of decompensation in cirrhosis, and 5% to 10% of patients with compensated cirrhosis develop ascites each year. The main factor of ascites formation is renal sodium retention due to activation of the renin-angiotensin-aldosterone system and sympathetic nervous system by the reduced effective volume secondary to splanchnic arterial vasodilation. Diagnostic paracentesis is indicated in all patients with a new onset of grade 2 or 3 ascites and in those admitted to hospital for any complication of cirrhosis. Read More

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August 2018
2 Reads

Author response to Letter to the Editor "Post-paracentesis hemoperitoneum - time to become more careful!"

Liver Int 2018 Sep;38(9):1698-1699

Digestive Diseases Section, Department of Medicine, Yale University, New Haven, CT, USA.

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September 2018
1 Read

Effect of Cell-Free DNA Screening vs Direct Invasive Diagnosis on Miscarriage Rates in Women With Pregnancies at High Risk of Trisomy 21: A Randomized Clinical Trial.

JAMA 2018 08;320(6):557-565

Paris Descartes University, Sorbonne Paris Cité, Institut Imagine, Paris, France.

Importance: Cell-free DNA (cfDNA) tests are increasingly being offered to women in the first trimester of pregnancies at a high risk of trisomy 21 to decrease the number of required invasive fetal karyotyping procedures and their associated miscarriages. The effect of this strategy has not been evaluated.

Objective: To compare the rates of miscarriage following invasive procedures only in the case of positive cfDNA test results vs immediate invasive testing procedures (amniocentesis or chorionic villus sampling) in women with pregnancies at high risk of trisomy 21 as identified by first-trimester combined screening. Read More

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August 2018
2 Reads

EUS-guided paracentesis and ascitic fluid analysis.

Authors:
Matthew A Chin

Endosc Ultrasound 2018 Jul-Aug;7(4):223-227

Division of Gastroenterology, John Muir Specialty Medical Group, Walnut Creek, CA, USA.

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August 2018
1 Read

Computed tomography-guided pericardiocentesis: a systematic review concerning contemporary evidence and future perspectives.

Ther Adv Cardiovasc Dis 2018 Nov 15;12(11):299-307. Epub 2018 Aug 15.

Cardiology Department, Vila Nova de Gaia / Espinho Hospital Center, Gaia, Portugal.

Background: Pericardial effusion (PE) can develop in several pathological scenarios, and is often initially evaluated by means of echocardiography. Computed tomography (CT) has been used as an aid in the management of patients presenting with PE, in selected cases. The role of CT-guided pericardiocentesis in contemporary practice, however, remains not fully ascertained. Read More

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November 2018
21 Reads

Controlled attenuation parameter (CAP) does not predict hepatic decompensation in patients with advanced chronic liver disease.

Liver Int 2018 Aug 14. Epub 2018 Aug 14.

Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Austria.

Background&aims: Assessment of hepatic steatosis by transient elastography (TE)-based controlled attenuation parameter (CAP) might predict hepatic decompensation. Therefore, we aimed to evaluate the prognostic value of CAP in patients with compensated advanced chronic liver disease (cACLD) and decompensated cirrhosis (DC).

Methods: 430 patients who underwent TE (liver stiffness ≥10kPa) and CAP measurements were included in this retrospective analysis. Read More

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August 2018
9 Reads

Cardiac tamponade in a patient with ankylosing spondylitis: a notable response to TNF inhibitors.

BMJ Case Rep 2018 Aug 11;2018. Epub 2018 Aug 11.

Cardiology, Maimonides Medical Center, Brooklyn, New York, USA.

Ankylosing spondylitis (AS) is a rheumatological disorder of the spine, and like many other rheumatological diseases, it can manifest as a systemic inflammation. We present a rare case of cardiac manifestations of AS in a 25-year-old man with recurrent chest pain and pericardial effusions. He initially presented with pleuritic chest pain, was diagnosed with cardiac tamponade and required emergent pericardiocentesis. Read More

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August 2018
5 Reads