144 results match your criteria Papulonecrotic Tuberculids

Cutaneous tuberculosis. Part I: Pathogenesis, classification, and clinical features.

J Am Acad Dermatol 2022 Feb 8. Epub 2022 Feb 8.

Department of Dermatology, University College of Medical Sciences & GTB hospital, Delhi, India.

Tuberculosis is an ancient disease that continues to affect an estimated 10 million people per year and is responsible for 1.4 million deaths per year. Additionally, the HIV epidemic and multi-drug resistance present challenges to disease control. Read More

View Article and Full-Text PDF
February 2022

Cutaneous tuberculosis. Part II: Complications, diagnostic workup, histopathological features, and treatment.

J Am Acad Dermatol 2022 Feb 8. Epub 2022 Feb 8.

Department of Dermatology, University College of Medical Sciences & GTB hospital, Delhi, India.

Despite the availability of effective treatment regimens for cutaneous tuberculosis, delayed diagnosis, infection with multi-drug resistant Mycobacterial strains, and co-infection with HIV present challenges to disease control. A delay in diagnosis can be mitigated by adequate sensitization of dermatologists to the clinical signs and symptoms, and incorporation of appropriate tests for diagnosis. All cases of cutaneous tuberculosis should be confirmed with histopathology, culture with or without molecular testing. Read More

View Article and Full-Text PDF
February 2022

Atypical presentations of cutaneous tuberculosis: Series of 10 cases.

Indian J Tuberc 2022 Jan 10;69(1):113-119. Epub 2021 Feb 10.

Department of Pathology, King George's Medical University, Lucknow, UP, 226003, India.

Cutaneous tuberculosis classically presents as Lupus vulgaris, scrofuloderma, tuberculosis verrucose cutis and tubercular abscess. Hypersensitivity reaction to the bacilli leads to Lichen scrofulosorum and papulonecrotic tuberculids. At the same time, it can have myriad of clinical presentations, many of which are still undescribed. Read More

View Article and Full-Text PDF
January 2022

Recurrent Genital Ulcers.

Urology 2021 01 24;147:33-34. Epub 2020 Oct 24.

Department of Dermatology, Venereology, and Leprosy, R.G.Kar Medical College, Kolkata, West Bengal, India.

Papulonecrotic tuberculid represents a hypersensitivity reaction to Mycobacterium tuberculosis or its products that disseminate through hematogenous route to the skin from an internal tuberculous focus. It is characterized by recurrent eruptions of asymptomatic, dusky red papules, which undergo ulceration and crusting, and eventually heal after a few weeks with varioliform scarring. Although it most commonly involves extragenital sites, isolated glans penis involvement has been reported very rarely. Read More

View Article and Full-Text PDF
January 2021

Papulonecrotic tuberculid secondary to Mycobacterium avium complex.

Cutis 2019 Nov;104(5):E11-E13

Department of Dermatology, Weill Cornell Medicine, New York, New York, USA.

View Article and Full-Text PDF
November 2019

A 36-Year-Old Moroccan Man Presenting with Widespread Papules and Pustules.

Dermatopathology (Basel) 2019 Jul-Sep;6(3):201-205. Epub 2019 Sep 11.

Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA.

Cutaneous manifestations of tuberculosis are uncommon, can be nonspecific, and may demonstrate a wide variety of morphologies, including ulcerative papules, verrucous plaques, or nodules. We report the case of a 36-year-old Moroccan man who presented with nearly 2 years of generalized folliculocentric pustules and nodules, night sweats, and weight loss. Workup revealed necrotic right axillary lymphadenopathy, multiple ill-defined hepatic lesions, and a positive interferon-γ release assay. Read More

View Article and Full-Text PDF
September 2019

Immune-mediated tuberculous uveitis - A rare association with papulonecrotic tuberculid.

Indian J Ophthalmol 2019 07;67(7):1207-1209

Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.

The tuberculids are a group of distinct clinicopathological form of skin lesions representing hypersensitivity reaction to hematogenous dissemination of Mycobacterium tuberculosis or its antigen from an underlying active or a silent focus of tuberculosis elsewhere in the body in an individual with a strong antituberculous cell-mediated immunity and by definition do not show bacilli on special stains and are culture-negative. Ocular involvement can occur in tuberculosis, both due to direct invasion by the bacilli as well as an immune-mediated reaction; however, immune-mediated tuberculous uveitis occurring as a hypersensitivity response in association with PNT has hardly been reported in the literature. Here we report one such rare case. Read More

View Article and Full-Text PDF

Papulonecrotic tuberculid after Bacillus Calmette-Guérin (BCG) vaccination with lung infiltration that mimics disseminated BCG infection.

J Dermatol 2019 08 27;46(8):e267-e268. Epub 2019 Feb 27.

Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.

View Article and Full-Text PDF

Nested Polymerase Chain Reaction and Cutaneous Tuberculosis.

Am J Dermatopathol 2019 Jun;41(6):428-435

Unidad de Investigación Médica en Inmunoquímica, Hospital de Especialidades, Centro Médico Nacional SXXI, IMSS, Mexico City, México.

The role of Mycobacterium tuberculosis in the etiology and pathogenesis of cutaneous tuberculosis is controversial because of the difficulties associated with demonstrating the presence of these mycobacteria in tuberculid cutaneous lesions by routinely available microbiological and histological techniques. In this study, we aimed to demonstrate the presence of M. tuberculosis in cutaneous tuberculosis. Read More

View Article and Full-Text PDF

Cutaneous tuberculosis and HIV infection at a referral centre in Rio de Janeiro, Brazil.

Mem Inst Oswaldo Cruz 2018 Jul 26;113(9):e180184. Epub 2018 Jul 26.

Fundação Oswaldo Cruz-Fiocruz, Instituto Nacional de Infectologia Evandro Chagas, Laboratório de Pesquisa Clínica em Dermatologia Infecciosa, Rio de Janeiro, RJ, Brasil.

Background: Cutaneous tuberculosis (CTB) is a rare extrapulmonary form of tuberculosis (TB). Despite the increase in the number of cases of TB and HIV, few cases of CTB have been reported.

Objective: To describe CTB cases among patients with HIV infection from a cohort with tuberculosis. Read More

View Article and Full-Text PDF

Cutaneous tuberculosis in China - A multicentre retrospective study of cases diagnosed between 1957 and 2013.

J Eur Acad Dermatol Venereol 2018 Apr;32(4):632-638

Department of Dermatology and Venereology, Southwest Hospital, Third Military Medical University, Chongqing, China.

Background: China has one of the largest populations with tuberculosis worldwide. Cutaneous tuberculosis (CTB) is a rare manifestation of mycobacterial infection. Although CTB is well described, it is important to periodically revisit the prevailing clinical and epidemiological features in most populated countries such as China, India, and Indonesia, where tuberculosis is still a major health problem. Read More

View Article and Full-Text PDF

Papulonecrotic Tuberculid.

Am J Trop Med Hyg 2017 10;97(4):987-988

Department of Dermatology, Venereology and Leprosy, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.

View Article and Full-Text PDF
October 2017

A Rare Case of Lupus Vulgaris with Papulonecrotic Tuberculid and Discoid Lupus Erythematosus.

Chin Med J (Engl) 2017 09;130(17):2134-2135

Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.

View Article and Full-Text PDF
September 2017

A rare case of Hodgkin's lymphoma presenting with papulonecrotic tuberculid.

BMJ Case Rep 2017 Jul 13;2017. Epub 2017 Jul 13.

Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

View Article and Full-Text PDF

Simultaneous Occurrence of Papulonecrotic Tuberculid and Erythema Induratum in an Asian Woman.

Skinmed 2016;14(6):457-459. Epub 2016 Dec 1.

National Skin Centre, Singapore.

A 31-year-old Indonesian woman presented with a 2-month history of recurrent painful nodules on the legs. Review of systems did not reveal any respiratory, gastrointestinal, or abdominal findings. She had been to Singapore working as a domestic helper for close to a year. Read More

View Article and Full-Text PDF
September 2018

Papulonecrotic Tuberculid: A Rare Skin Manifestation in a Child with Mesenteric Tuberculous Lymphadenopathy.

Acta Derm Venereol 2017 01;97(1):137-138

Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.

View Article and Full-Text PDF
January 2017

Multifocal tuberculous gummas and bilateral scrofuloderma followed by papulonecrotic tuberculids developing during anti-tubercular therapy.

Indian J Dermatol Venereol Leprol 2016 Jul-Aug;82(4):424-6

Department of Dermatology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.

View Article and Full-Text PDF

Tuberculids: cutaneous indicator diseases of Mycobacterium tuberculosis infection in young patients.

J Eur Acad Dermatol Venereol 2016 Sep 26;30(9):1590-3. Epub 2016 May 26.

Emma Childrens' Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

Background: In the past years the incidence of tuberculosis has dropped significantly in most parts of Europe and the presentation of symptomatic tuberculosis cases have become increasingly rare. With the recent influx of refugees in Europe coming from tuberculosis endemic areas like the Middle East and Africa, it is expected that the incidence of tuberculosis will increase.

Objectives: Cutaneous symptoms are important hallmarks that can be of aid for the correct diagnosis of an underlying disease, like tuberculosis. Read More

View Article and Full-Text PDF
September 2016

Clinicohistological Profile of Cutaneous Tuberculosis in Central Nepal.

M Mathur S N Pandey

Kathmandu Univ Med J (KUMJ) 2014 Oct-Dec;12(48):238-41

Department of Dermatology College of Medical Sciences- Teaching Hospital Bharatpur, Chitwan, Nepal.

Background: There are few studies on cutaneous tuberculosis in Nepal.

Objective: To analyse the epidemiological, clinical and histological patterns of cutaneous TB over the past 5 years.

Method: Patients with cutaneous tuberculosis diagnosed from January 2010 to December 2014 at College of Medical Sciences, Chitwan, Nepal were included in the study. Read More

View Article and Full-Text PDF

Papulonecrotic tuberculid with scrofuloderma: an uncommon association.

Vinita Gupta

J Clin Diagn Res 2015 Feb 1;9(2):WD03-4. Epub 2015 Feb 1.

Assistant Professor, Department of Skin and VD, SGT Medical College and Research Institute , Budhera, Gurgaon, Haryana, India .

Cutaneous tuberculosis can be classified as true cutaneous tuberculosis and tuberculids which is regarded as a hypersensitivity reaction to M. tuberculosis in patients with a high degree of tuberculin sensitivity. Papulonecrotic tuberculid (PNT) is a form of tuberculid. Read More

View Article and Full-Text PDF
February 2015

Clinicopathologic spectrum of cutaneous tuberculosis: a retrospective analysis of 165 Indians.

Am J Dermatopathol 2015 Jun;37(6):444-50

Departments of *Pathology, and †Dermatology and STD, University College of Medical Sciences and associated GTB Hospital, Delhi, India; and ‡Dermato-Venereology (Skin/VD) Centre, Sehgal Nursing Home, Delhi, India.

Background: Although cutaneous tuberculosis (CTB) is well described, it is wise to periodically revisit the prevailing clinical and epidemiological features, of this somewhat uncommon entity in developed nations that is also usually neglected in national tuberculosis control programs in countries where tuberculosis is a major health problem, to maintain heightened awareness as the HIV pandemic runs its course.

Methods: Medical records of 165 cases of CTB, diagnosed from 2007 to 2010, were studied. The diagnosis in each was made on the basis of well-conceived and described criteria. Read More

View Article and Full-Text PDF

Molluscum-like papules as a presentation of early papulonecrotic tuberculid in association with nodular tuberculid in a male with asymptomatic active pulmonary tuberculosis.

J Cutan Med Surg 2015 Mar-Apr;19(2):159-62. Epub 2015 Mar 5.

Division of Dermatology, University of Toronto, Toronto, ON.

Background/objectives: The clinical and histopathologic findings of a rare simultaneous occurrence of papulonecrotic tuberculid and nodular tuberclid in a patient with active but asymptomatic pulmonary tuberculosis are presented. Papulonecrotic tuberculid was observed at a very early stage, presenting as molluscum-like lesions. This has been described once in the literature. Read More

View Article and Full-Text PDF
September 2015

Concurrent lichen scrofulosorum and papulonecrotic tuberculid in a patient with tubercular lymphadenitis.

Indian J Dermatol Venereol Leprol 2014 Sep-Oct;80(5):483

Department of Dermatology and Sexually Transmitted Diseases, Lady Hardinge Medical College and Suchita Kriplani Hospital, Shaheed Bhagat Singh Marg, New Delhi, India.

View Article and Full-Text PDF

Papulonecrotic tuberculid-clinicopathologic and molecular features of 12 Indian patients.

Dermatol Pract Concept 2014 Apr 30;4(2):17-22. Epub 2014 Apr 30.

Division of Infectious Diseases, St. John's Research Institute; John Nagar, Bangalore, India.

Background: Papulonecrotic tuberculid (PNT) is said to be a hypersensitivity reaction to M. tuberculosis. Some reports indicate that organisms are demonstrable by polymerase chain reaction (PCR). Read More

View Article and Full-Text PDF

Perforating granuloma annulare mimicking papulonecrotic tuberculid.

An Bras Dermatol 2013 Nov-Dec;88(6 Suppl 1):101-4

Universidade Federal de São Paulo, Department of Dermatology, São PauloSP, Brazil.

A case is reported of a patient presenting lymph node tuberculosis and cutaneous lesions resembling papulonecrotic tuberculid, but histologically compatible with perforating granuloma annulare and which responded satisfactorily to antituberculous therapy. This is probably one of the first reports of the association of perforating granuloma annulare and tuberculosis, and it is important therefore to highlight the relevance of this disorder in the differential diagnosis of papulonecrotic tuberculid and to raise the hypothesis that this entity should also be considered to be a variant of tuberculid. Read More

View Article and Full-Text PDF

Papulonecrotic tuberculid of glans penis: A common disease at an uncommon site.

Indian J Sex Transm Dis AIDS 2013 Jul;34(2):132-4

Department of Dermatology, Lokmanya Tilak Municipal General Hospital, Sion, Mumbai, Maharashtra, India.

A 65-year-old man presented with multiple asymptomatic papulo-pustules and ulcers over glans penis since last 1 year. The lesions used to resolve spontaneously in a few days with scarring. The clinical features and histopathology were suggestive of papulonecrotic tuberculids of the glans penis. Read More

View Article and Full-Text PDF

[Papulonecrotic tuberculid: case report].

Arch Argent Pediatr 2013 Jan-Feb;111(1):e5-7

Departamento de Dermatología, Facultad de Medicina, Dicle University, Facultad de Medicina, Diyarbakir, Turquía.

A 12-year-old girl was seen with widespread millimetric papules which resolved leaving varioliform scars. Tuberculin test was strongly reactive. Underlying pulmonary tuberculosis was diagnosed. Read More

View Article and Full-Text PDF
January 2014