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BMJ Open Ophthalmol 2020 25;5(1):e000513. Epub 2020 Jun 25.

Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, UK.

Objective: Trichilemmoma is a benign tumour derived from the outer root sheath of hair follicles. Trichilemmoma can be associated with basal cell carcinoma (BCC), either as a collision lesion or from malignant transformation. This study evaluates malignancy associated with eyelid trichilemmoma and principles of treatment. Read More

J Cosmet Laser Ther 2020 Jun 4:1-4. Epub 2020 Jun 4.

Department of Ophthalmology, Centro Hospitalar Vila Nova de Gaia/Espinho , Vila Nova de Gaia, Portugal.

The purpose of this prospective cohort study, including consecutively selected patients, was to evaluate the outcomes of Nd:YVO laser-assisted photocoagulation for the removal of benign eyelid lesions. An emulsion of lidocaine and prilocaine was used for dermal analgesia and subcutaneous injection of 2% lidocaine was performed as needed. Follow-up included two visits, at day 15 and 45 postoperatively, in order to assess time of wound healing, postoperative complications, need for additional treatment, and patient's satisfaction. Read More

Orbit 2020 Mar 5:1-2. Epub 2020 Mar 5.

Govindram Seksaria Institute of Dacryology, L.V.Prasad Eye Institute, Hyderabad, India.

A 46-year-old lady presented with progressively growing mass from the inner side of the right upper eyelid. The mass was elevated, pinkish with surface vessels, engulfing the puncta. Careful evaluation revealed a patent punctal opening. Read More

J Ophthalmic Vis Res 2019 Oct-Dec;14(4):509-512. Epub 2019 Oct 24.

Department of Pathology, UP University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India.

Purpose: To highlight the importance of histopathological evaluation of a lid mass to prognosticate the disease. We report a case of ulcerative squamous cell papilloma with clinical features suggesting malignancy.

Case Report: A 65-year-old man presented with a rapidly enlarging mass in the left upper eyelid, with clinical features suggesting a squamous cell carcinoma. Read More

Case Rep Ophthalmol Med 2019 29;2019:5830493. Epub 2019 Oct 29.

Department of Ophthalmology, University of Szeged, Szeged, Hungary.

Squamous cell papilloma (SCP) is generally a human papillomavirus (HPV) induced exophytic or endophytic proliferation on the surface of the skin, oral cavity, larynx, esophagus, cervix, vagina, and anal canal. The endophytic type SCP can cause differential diagnostic difficulties with keratoacanthoma, inverted follicular keratosis, and squamous cell carcinoma; however, these lesions are not associated with HPV infection. The authors present a female patient who noticed an extremely rapidly growing tumor destructing the left lower eyelid. Read More

Zhonghua Yan Ke Za Zhi 2019 Nov;55(11):847-853

Department of Ophthalmology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.

To investigate the anatomical region, histopathological classification and histogensis distribution of ocular mass lesions in South China. Retrospective cases study. The clinical and pathological data of 7 910 samples with ocular (adnexal) tumors or proliferative lesions which were examined from January 2000 to May 2018 were retrospectively retrieved. Read More

Surv Ophthalmol 2020 Mar - Apr;65(2):227-238. Epub 2019 Sep 23.

Department of Ophthalmic Pathology, Wills Eye Hospital, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Over several months, a painless, multinodular, non-erythematous swelling of the deep tissues of his left upper eyelid developed in a 63-year-old man. An excisional biopsy with histopathologic evaluation disclosed a unique sebaceous papilloma within a cyst lined by non-keratinizing squamous epithelium that focally displayed a variably thick, superficial, eosinophilic cuticular layer. Immunohistochemical staining demonstrated that the tumor and its epithelial cystic lining had a profile consistent with Meibomian gland duct epithelium. Read More

Vet J 2019 Aug 4;250:1-5. Epub 2019 Jun 4.

Department of Biomedical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA.

Canine papillomatosis is mainly attributed to papillomavirus infections. Papillomavirus DNA is also frequently identified in healthy skin, and evidence of high papillomavirus diversity complicates this simplistic view of causality. The aim of this study was to determine how frequently canine papillomas contain papillomavirus DNA and express viral protein, and how these factors correlate to the histology and anatomic location. Read More

Indian J Pathol Microbiol 2019 Jul-Sep;62(3):481-482

Department of Ophthalmology, Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Zhonghua Yan Ke Za Zhi 2019 May;55(5):369-373

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

To summarize and analyze the clinical manifestation of conjunctival papilloma, its relationship with human papillomavirus (HPV) infection and the recurrence after the combination of operation and pharmacotherapy. A retrospective case series study. Analysis of 40 patients (41 eyes) with conjunctival papilloma treated at Peking Union Medical College Hospital from January 2008 to June 2018 was performed. Read More

Proc (Bayl Univ Med Cent) 2019 Jan 16;32(1):121-123. Epub 2019 Jan 16.

Department of Otolaryngology, Baylor Scott & White-Temple/Texas A&M UniversityTempleTexas.

Sinonasal papillomas, also known as Schneiderian papillomas, are benign but infiltrative epithelial neoplasms that arise from ectodermally derived pseudostratified ciliated (or Schneiderian) epithelium that lines the sinonasal tract and nasal cavity. We describe a rare case of a sinonasal papilloma confined to the lacrimal duct and sac in a 45-year-old man who presented with 10 months of right-sided epiphora and swelling of his medial right lower eyelid. He was found to have a 10 × 10 mm area of distension near the right lacrimal sac and underwent an external dacryocystorhinostomy. Read More

Int J Oncol 2019 May 19;54(5):1503-1510. Epub 2019 Mar 19.

Department of Ophthalmology, University Hospital of Heraklion, 71110 Heraklion, Greece.

Human papillomavirus (HPV) infection has been implicated as a primary cause of lesions in the anogenital region, skin, oropharynx and respiratory tract. Additionally, the role of HPV in the pathogenesis of ocular surface disease has also been extensively studied. Conjunctival papilloma development has been strongly associated with the HPV infection of certain subtypes. Read More

Arq Bras Oftalmol 2019 Mar-Apr;82(2):107-110. Epub 2019 Jan 24.

Centro de Oncologia Ocular, Departamento de Ofalmologia e Ciências Visuais, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Purpose: To evaluate the first three years of The Amazon Ocular Oncology Center, the first ocular cancer center in the North of Brazil.

Methods: Here, we report patient information including patients' age, gender, diagnosis, treatment, and city of origin.

Results: Two hundred and twenty-one patients were included on this study: 160 (72%) patients came from the city of Manaus, 52 (24%) from other cities in Amazonas, and 9 (4%) from other states. Read More

Klin Monbl Augenheilkd 2019 Jan 28;236(1):50-53. Epub 2019 Jan 28.

Klinik für Augenheilkunde, Universitätsklinikum Münster, Münster.

Purpose: Cryotherapy as a destructive procedure is an important alternative to the surgical excision of eyelid tumors.

Methods: We report our own experiences in the cryotherapy of large upper eyelid papillomas using spray- and contact-freezing.

Results/conclusions: Cryotherapy gave excellent results in the treatment of unusually large papillomas. Read More

Cesk Slov Oftalmol Winter 2018;74(3):92-97

The etiology of papilloma formation is multifactorial. There is a strong association between human papillomavirus (HPV) and the development of these conjunctival lesions. HPV is tumorigenic and commonly produces benign tumors with low malignant potential. Read More

Dermatol Ther 2019 07 28;32(4):e12815. Epub 2019 Jan 28.

Department of dermatology, NHC/Ministry of Education/Liaoning Province Key Laboratory of Immunodermatology (China Medical University) The First Hospital of China Medical University, No. 155 Nanjing Bei Street, Heping District, Shenyang, Liaoning, P.R. China.

A female Cushing's syndrome patient had been suffering from extensive viral warts for months. She was diagnosed with flat warts, common warts and plantar warts. The plantar warts on her right foot were initially treated using local hyperthermia at 44°C for 30 min according to a defined protocol, followed by treatment targeting a common wart on her left thumb. Read More

Jpn J Ophthalmol 2019 Mar 2;63(2):210-214. Epub 2019 Jan 2.

Department of Ophthalmology, Rio Hortega University Hospital, Dulzaina St. 2, 47012, Valladolid, Spain.

Purpose: To evaluate the demographic, clinical, and histopathologic characteristics of periocular inverted follicular keratosis (IFK), a very rare lesion with poorly defined characteristics.

Study Design: Retrospective case series.

Methods: We evaluated 11 patients with clinically diagnosed IFK confirmed by histologic analysis. Read More

Int J Ophthalmol 2018 18;11(11):1835-1841. Epub 2018 Nov 18.

Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300020, China.

Aim: To describe the histopathologic and clinical features of eyelid tumor cases from Tianjin Eye Hospital during 2002 to 2015.

Methods: In this retrospective study, a total of 2228 cases of eyelid tumors with pathologic diagnoses were enrolled. The eyelid tumors were classified into three groups according to tumor origin: epidermal, adnexal and miscellaneous, including melanocytic, neural and vascular lesions. Read More

Middle East Afr J Ophthalmol 2018 Apr-Jun;25(2):111-114

Department of Pathology, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Primary conjunctival rhabdomyosarcoma (RMS) is a rare entity that can present with or without papillomatous features. A 5-year-old Asian boy was referred for a rapidly growing conjunctival tumor in the superior fornix of the left eye. Surgical excision yielded a 28 mm multilobulated papillomatous specimen that exhibited histopathologic and immunohistochemical features consistent with embryonal (botryoid) RMS. Read More

Vet Ophthalmol 2019 May 27;22(3):256-264. Epub 2018 Jul 27.

Insight Veterinary Specialty Pathology, Austin, TX, USA.

Purpose: To evaluate the recurrence frequency and the time to recurrence of canine palpebral masses treated with debulking and cryotherapy.

Methods: Medical records of dogs that underwent debulking and cryotherapy for palpebral masses from December 2010 to November 2015 at the University of Minnesota's Veterinary Medical Center were reviewed. A telephone survey with owners was used to determine recurrence and time to recurrence. Read More

Ann Otol Rhinol Laryngol 2018 Sep 4;127(9):637-642. Epub 2018 Jul 4.

2 Department of Otolaryngology, West Virginia University, Morgantown, West Virginia, USA.

Introduction: Functional endoscopic sinus surgery for frontal sinus disease has obviated the need for external approaches. Special circumstances such as acute infection with orbital involvement or significant lateral sinus disease frequently require adjunct access. We describe the clinical outcomes of a combined upper eyelid crease and endoscopic approach for lateral frontal sinus disease with orbital extension. Read More

PLoS One 2018 21;13(2):e0193161. Epub 2018 Feb 21.

Ophthalmology department, Chiang Mai University Hospital, Chiang Mai, Thailand.

Human immunodeficiency virus (HIV) causes impairment to the human immune system which leads to immunocompromised conditions, including ocular complications. Several important HIV-associated disorders may involve the anterior segment, ocular surface, and adnexae organ such as dry eye, blepharitis which reduce quality of life of patients. In present, potent antiretroviral therapies HAART (highly active antiretroviral therapy) has improved the length and quality of life which may lead to an increased prevalence of anterior segment ocular disorders. Read More

Graefes Arch Clin Exp Ophthalmol 2018 Jan 9;256(1):193-198. Epub 2017 Nov 9.

Department of Ophthalmology, University General Hospital of Heraklion, Crete, Greece.

Purpose: The evaluation of a non-invasive detection method for human papilloma virus (HPV) in ophthalmic pterygia.

Methods: Cotton swab samples and corresponding tissue specimens were collected from 21 ophthalmic pterygia of 21 patients. HPV detection and typing were performed by real-time PCR. Read More

Ophthalmic Plast Reconstr Surg 2018 Jan/Feb;34(1):e1-e3

Department of Ophthalmology and Visual Sciences, and Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.

A 45 year-old woman presented with blurred vision and irritation of the left eye. Clinical examination revealed a superior palpebral conjunctival lesion consistent with a diagnosis of papilloma. She was lost to follow up despite repeated attempts to schedule a biopsy, and presented again after an extended period with bilateral disease. Read More

Laryngoscope 2018 01 13;128(1):3-9. Epub 2017 Apr 13.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.

Objectives: Sinonasal inverting papilloma (IP) is a benign but locally aggressive mucosal neoplasm with a high recurrence rate. Extension into the frontal sinus presents surgical challenges for endonasal resection. This study presents an orbitofrontal approach for managing extensive IP. Read More

Can J Ophthalmol 2017 Feb 16;52(1):e30-e31. Epub 2016 Nov 16.

Laboratoire de Pathologie Clinique et Expérimentale, Hôpital Pasteur, Nice, France.

Eye Contact Lens 2018 Sep;44 Suppl 1:S77-S81

Departments of Ophthalmology (H.Y., M.D., T.Y., S.D., Y.S., J.S.), and Pathology and Laboratory Medicine (J.M., Y.T.), Ichikawa General Hospital, Tokyo Dental College, Chiba, Japan; and Department of Ophthalmology (H.Y., M.D., K.T.), Keio University School of Medicine, Tokyo, Japan.

Purpose: To investigate the association between recurrence of conjunctival papillomas and presence of atypical epithelial changes in patients undergoing surgical excision for conjunctival papilloma.

Methods: We retrospectively reviewed 1,195 ophthalmic pathology specimens from 2004 to 2014 at Ichikawa General Hospital. Pathologic specimens of 5 patients with a final diagnosis of "conjunctival papilloma" were stained with hematoxylin-eosin, Ki 67, p53, human papillomavirus (HPV) 16 and 18 antibodies. Read More

Indian J Ophthalmol 2016 Oct;64(10):778-780

Department of Ophthalmology, Sankara Eye Hospital, Ludhiana, Punjab, India.

A 2-year-old boy presented with a recurrent strawberry-like reddish mass arising from the left caruncular region for 8 months. An incisional biopsy was performed elsewhere 2 months earlier, followed by an increase in size of mass, significant epiphora, and intermittent bleeding. On examination, exuberant exophytic gelatinous mass with multifocal origin was observed arising from inferior forniceal conjunctiva and caruncle. Read More

Dis Aquat Organ 2016 Oct;121(3):233-240

Laboratório ECOPESCA - Biologia do Nécton e Ecologia Pesqueira, Departamento de Biologia Marinha, Pós Graduação em Biologia Marinha e Ambientes Costeiros, Instituto de Biologia, Universidade Federal Fluminense, 24001-970 Niterói, Rio de Janeiro, Brazil.

Fibropapillomatosis (FP) is a multifactorial disease that affects all species of marine turtles, including green turtles Chelonia mydas (Linnaeus, 1758). It is characterised by the development of internal or external tumours that, depending on their locations and sizes, may intensely impact the health condition of sea turtles. The goal of this study was to characterise the disease in C. Read More

Am J Clin Pathol 2016 Mar;145(3):385-92

From the Henry C. Witelson Ocular Pathology Laboratory, McGill University, Montreal, Canada;

Objectives: The aim of this study was to evaluate heat shock protein 90 (HSP90) expression in squamous lesions (SLs) and to assess its diagnostic value for different lesions within the SL spectrum.

Methods: A total of 70 conjunctival SLs, including 19 papillomas, 22 cases of conjunctival intraepithelial neoplasia (ConINs) I, 11 cases of ConIN II, six cases of ConIN III, and 12 squamous carcinomas (sqCAs), were evaluated using the German immunoreactive score against HSP90.

Results: Cytoplasmic HSP90 expression differed between low- and high-grade lesions (P < . Read More

Ophthalmology 2015 Nov;122(11):2154

Department of Ophthalmology and Visual Sciences, University of Wisconsin - Madison, Madison, Wisconsin.

Diagn Pathol 2015 Sep 24;10:175. Epub 2015 Sep 24.

Department of Pathology, University of California San Diego and VA San Diego Healthcare System, San Diego, CA, USA.

Background: p16 expression is a well established biomarker of cervical dysplasia and carcinoma arising from high risk human papilloma virus infection. Increased p16 expression is also seen in squamous neoplasms arising at other sites, including head, neck, and oropharyngeal tract. Squamous lesions are also frequently encountered at ocular surface and peri-orbital skin sites, but the prevalence of increased p16 expression in these lesions has been poorly studied. Read More

Asian Pac J Cancer Prev 2015 ;16(10):4265-9

Ophthalmology, Medical School, Gulhane Military Medical Academy, Ankara, Turkey E-mail :

Introduction: The aim of the study was to explore the distribution of eyelid tumors in Ankara, the capital city of Turkey, from a histopathological point of view.

Materials And Methods: Medical records of 1,502 patients who had eyelid surgery because of tumoral lesions were retrospectively reviewed after obtaining institutional review board approval. A total of 1,541 lesions with histopathologic diagnosis were included. Read More

Middle East Afr J Ophthalmol 2015 Apr-Jun;22(2):230-2

Department of Internal Medicine, Medical School, University of Ioannina, Greece.

Aims: The aim was to describe the epidemiology of primary eyelid tumors over a 30-year period at the Ioannina University Eye Clinic, Greece.

Materials And Methods: This retrospective case series examined the histopathology of eyelid tumor specimens of patients treated between 1983 and 2012. Data were collected on patient age, gender, location of the lesion, extent of tumor excision and recurrence. Read More

J Med Case Rep 2014 Dec 29;8:466. Epub 2014 Dec 29.

Henry C, Witelson Ocular Pathology Laboratory, McGill University, 3775 Rue University, Room 216, Montreal, Quebec, Canada.

Introduction: Superficial epithelioma with sebaceous differentiation is a rare benign epithelial neoplasm. It usually involves the head, neck or the back of a middle-age person. To the best of our knowledge, two ocular cases have been reported in the literature. Read More

Vet Pathol 2015 Jul 28;52(4):676-80. Epub 2014 Oct 28.

The Comparative Ocular Pathology Laboratory of Wisconsin, School of Veterinary Medicine, the University of Wisconsin-Madison, Madison, WI, USA

Papillomas of the conjunctival surface in people can be of viral or nonviral origin and are found in high association with human papillomavirus. Canine conjunctival papillomas are seldom described, and published accounts have mostly been associated with canine oral papillomavirus infection. Here, we describe conjunctival squamous papillomas that do not express papillomavirus proteins and compare them with papillomavirus-associated conjunctival papillomas. Read More

Ann Otol Rhinol Laryngol 2014 Dec 18;123(12):826-30. Epub 2014 Jun 18.

Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA

Objective: This study aimed to describe the hybrid lid crease approach in conjunction with functional endoscopic sinus surgery (FESS) for lateral frontal sinus disease with orbital extension.

Study Design: Retrospective case review.

Methods: Patients undergoing hybrid lid crease approach with FESS for frontal sinus disease were reviewed retrospectively. Read More

Surv Ophthalmol 2014 Sep-Oct;59(5):540-7. Epub 2014 Jan 28.

Department of Ophthalmology, Ophthalmic Plastic Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.

A 46-year-old woman was evaluated for a "recurring papilloma" of the left medial upper eyelid margin. Beneath the papillary lesion medial to the punctum was a 5-mm diameter cutaneous mass thought to be cystic. After excisional biopsy, histopathologic analysis documented the presence of an epidermal keratinizing squamous papilloma surmounting a circumscribed dermal papillary hidradenoma composed of deeply eosinophilic columnar cells. Read More

Trop Med Int Health 2013 Dec 30;18(12):1424-43. Epub 2013 Oct 30.

Department of Ophthalmology, University of Nairobi, Nairobi, Kenya; London School of Hygiene and Tropical Medicine, London, UK.

Objectives: To describe the epidemiology and an aetiological model of ocular surface squamous neoplasia (OSSN) in Africa.

Methods: Systematic and non-systematic review methods were used. Incidence was obtained from the International Agency for Research on Cancer. Read More

Ophthalmic Plast Reconstr Surg 2013 Nov-Dec;29(6):454-7

*Orbital Oncology and Ophthalmic Plastic Surgery Program, Department of Plastic Surgery, †Department of Radiation Oncology, and ‡Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, U.S.A.

Purpose: To determine the rates of globe-sparing treatment and useful final visual function in patients with primary lacrimal sac/nasolacrimal duct carcinomas treated with multidisciplinary therapy.

Methods: The medical records of 14 patients with primary lacrimal sac/nasolacrimal duct carcinoma treated at 1 institution were retrospectively reviewed.

Results: The patients were 9 men and 5 women; the median age at diagnosis was 58. Read More

Middle East Afr J Ophthalmol 2013 Jul-Sep;20(3):187-92

Ophthalmic Research Center, Shahid Beheshti Medical University, Department of Ophthalmology, Labbafinejad Hospital, Tehran, Iran.

Purpose: The purpose of this study was to evaluate the demographics and clinical features of eyelid masses in a tertiary eye hospital over a 10-year period.

Materials And Methods: A retrospective chart review was performed for patients admitted with eyelid tumors from 2000 to 2010. Data were collected and analyzed on the demographic features, location of the tumor, types of treatment, and pathologic findings. Read More

Zhonghua Yan Ke Za Zhi 2013 Jan;49(1):37-40

Henan Eye Institute, Henan Key Laboratory of Keratonosus, Zhengzhou 450003, China.

Objective: To analyze the pathological classification of ocular tumor in children.

Methods: 213 cases (214 eyes) of ocular tumor in children below 14 years old between January 2001 and December 2007 in Henan Eye Institute were reviewed retrospectively, the pathological classification were made according to the location and nature of the tumor.

Results: There were 17 eyes (7. Read More

J Biomed Res 2012 Nov 4;26(6):474-7. Epub 2012 Apr 4.

Department of Dermatology, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China;

A 55-year-old Chinese man presented with an asymptomatic pedunculated elevation on his left lower eyelid which had been gradually increasing in size during the past three years. The patient was diagnosed with eyelid papilloma by pathological examination. Concomitantly, the patient developed open comedones with a bilateral linear distribution, along with oblique wrinkle lines in his infraorbital regions. Read More

Can J Ophthalmol 2012 Dec 25;47(6):e47-8. Epub 2012 Sep 25.

Vet Ophthalmol 2013 Jul 9;16 Suppl 1:105-12. Epub 2012 Aug 9.

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

A 6-year-old female spayed Chihuahua was presented for the evaluation of generalized pigmented cutaneous masses, one of which was present on the lower right eyelid. The dog was not on immunosuppressive medications and did not have historical or laboratory evidence of underlying endocrine disease, including hypothyroidism and hyperadrenocorticism. Histopathology, immunohistochemistry, and polymerase chain reaction of a cutaneous biopsy from the left antebrachium containing representative lesions confirmed viral papillomatosis. Read More

BMJ Case Rep 2012 May 8;2012. Epub 2012 May 8.

Allergy and Clinical Immunology, University of Torino and AO Ordine Mauriziano, Torino, Italy.

A 17-year-old girl reported generalised urticaria, eyelid angioedema, rhino-conjunctivitis, dyspnoea and wheezing 1 h after third intramuscular administration of quadrivalent human papilloma virus vaccine (Gardasil). She was treated with antihistamine, and corticosteroids with prompt relief of rhinitis and dyspnoea, while urticaria and angioedema lasted 24 h. Intradermal test with Gardasil, which contains polysorbate 80 (PS80), resulted positive, while skin tests with the bivalent vaccine were negative. Read More

Niger J Clin Pract 2012 Jan-Mar;15(1):89-92

Department of Pathology, University College Hospital, Ibadan, Nigeria.

Background: There is very limited literature on squamous papillomas of the conjunctiva from Nigeria and sub-Saharan Africa. In an attempt to contribute to the literature on the subject, we studied the clinicopathological characteristics of patients histologically diagnosed with squamous papilloma of the conjunctiva in Ibadan, Nigeria.

Materials And Methods: Clinical and pathological records of patients with histological diagnosis of squamous papilloma of the conjunctiva made in the Department of Pathology, University College Hospital, Ibadan, between January 1985 and December 2004, were reviewed. Read More

Eye Sci 2011 Sep;26(3):148-53

Sun Yat-sen University, Guangzhou, China.

Purpose: Corneal tumors are rare in clinical practice. There was a paucity of data on the incidence of various corneal tumors, their clinical and pathological features and surgical management, especially on large patient samples.

Methods: The medical records of 39 patients with corneal tumors referred to Zhongshan Ophthalmic Center, Sun Yat-sen University, China from Jan 1,1996 to Dec 31,2002 were reviewed retrospectively. Read More

Cutan Ocul Toxicol 2012 Mar 2;31(1):77-80. Epub 2011 Sep 2.

Department of Ophthalmology, Hospital of Navarra, Pamplona, Spain.

Context: Ethyl chloride (EC) is a fast-acting vapo-coolant spray that provides rapid, transient, local analgesia for minor invasive procedures. Although the application of EC has decreased, it can be used as a cryoanalgesic agent in minor surgical procedures.

Objective: Despite the widespread use of EC as a local anesthetic, there are few reported cases of serious adverse side effects. Read More