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Proc (Bayl Univ Med Cent) 2019 Jan 16;32(1):121-123. Epub 2019 Jan 16.

Department of Otolaryngology, Baylor Scott & White-Temple/Texas A&M UniversityTempleTexas.

Sinonasal papillomas, also known as Schneiderian papillomas, are benign but infiltrative epithelial neoplasms that arise from ectodermally derived pseudostratified ciliated (or Schneiderian) epithelium that lines the sinonasal tract and nasal cavity. We describe a rare case of a sinonasal papilloma confined to the lacrimal duct and sac in a 45-year-old man who presented with 10 months of right-sided epiphora and swelling of his medial right lower eyelid. He was found to have a 10 × 10 mm area of distension near the right lacrimal sac and underwent an external dacryocystorhinostomy. Read More

Arq Bras Oftalmol 2019 Mar-Apr;82(2):107-110. Epub 2019 Jan 24.

Centro de Oncologia Ocular, Departamento de Ofalmologia e Ciências Visuais, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Purpose: To evaluate the first three years of The Amazon Ocular Oncology Center, the first ocular cancer center in the North of Brazil.

Methods: Here, we report patient information including patients' age, gender, diagnosis, treatment, and city of origin.

Results: Two hundred and twenty-one patients were included on this study: 160 (72%) patients came from the city of Manaus, 52 (24%) from other cities in Amazonas, and 9 (4%) from other states. Read More

Cesk Slov Oftalmol Winter 2018;74(3):92-97

The etiology of papilloma formation is multifactorial. There is a strong association between human papillomavirus (HPV) and the development of these conjunctival lesions. HPV is tumorigenic and commonly produces benign tumors with low malignant potential. Read More

Dermatol Ther 2019 Jan 11:e12815. Epub 2019 Jan 11.

Department of dermatology, NHC/Ministry of Education/Liaoning Province Key Laboratory of Immunodermatology (China Medical University) The First Hospital of China Medical University, No. 155 Nanjing Bei Street, Heping District, Shenyang, Liaoning, P.R. China.

A female Cushing's syndrome patient had been suffering from extensive viral warts for months. She was diagnosed with flat warts, common warts and plantar warts. The plantar warts on her right foot were initially treated using local hyperthermia at 44°C for 30 min according to a defined protocol, followed by treatment targeting a common wart on her left thumb. Read More

Jpn J Ophthalmol 2019 Mar 2;63(2):210-214. Epub 2019 Jan 2.

Department of Ophthalmology, Rio Hortega University Hospital, Dulzaina St. 2, 47012, Valladolid, Spain.

Purpose: To evaluate the demographic, clinical, and histopathologic characteristics of periocular inverted follicular keratosis (IFK), a very rare lesion with poorly defined characteristics.

Study Design: Retrospective case series.

Methods: We evaluated 11 patients with clinically diagnosed IFK confirmed by histologic analysis. Read More

Int J Ophthalmol 2018 18;11(11):1835-1841. Epub 2018 Nov 18.

Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300020, China.

Aim: To describe the histopathologic and clinical features of eyelid tumor cases from Tianjin Eye Hospital during 2002 to 2015.

Methods: In this retrospective study, a total of 2228 cases of eyelid tumors with pathologic diagnoses were enrolled. The eyelid tumors were classified into three groups according to tumor origin: epidermal, adnexal and miscellaneous, including melanocytic, neural and vascular lesions. Read More

Middle East Afr J Ophthalmol 2018 Apr-Jun;25(2):111-114

Department of Pathology, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Primary conjunctival rhabdomyosarcoma (RMS) is a rare entity that can present with or without papillomatous features. A 5-year-old Asian boy was referred for a rapidly growing conjunctival tumor in the superior fornix of the left eye. Surgical excision yielded a 28 mm multilobulated papillomatous specimen that exhibited histopathologic and immunohistochemical features consistent with embryonal (botryoid) RMS. Read More

Vet Ophthalmol 2018 Jul 27. Epub 2018 Jul 27.

Insight Veterinary Specialty Pathology, Austin, TX, USA.

Purpose: To evaluate the recurrence frequency and the time to recurrence of canine palpebral masses treated with debulking and cryotherapy.

Methods: Medical records of dogs that underwent debulking and cryotherapy for palpebral masses from December 2010 to November 2015 at the University of Minnesota's Veterinary Medical Center were reviewed. A telephone survey with owners was used to determine recurrence and time to recurrence. Read More

Ann Otol Rhinol Laryngol 2018 Sep 4;127(9):637-642. Epub 2018 Jul 4.

2 Department of Otolaryngology, West Virginia University, Morgantown, West Virginia, USA.

Introduction: Functional endoscopic sinus surgery for frontal sinus disease has obviated the need for external approaches. Special circumstances such as acute infection with orbital involvement or significant lateral sinus disease frequently require adjunct access. We describe the clinical outcomes of a combined upper eyelid crease and endoscopic approach for lateral frontal sinus disease with orbital extension. Read More

PLoS One 2018 21;13(2):e0193161. Epub 2018 Feb 21.

Ophthalmology department, Chiang Mai University Hospital, Chiang Mai, Thailand.

Human immunodeficiency virus (HIV) causes impairment to the human immune system which leads to immunocompromised conditions, including ocular complications. Several important HIV-associated disorders may involve the anterior segment, ocular surface, and adnexae organ such as dry eye, blepharitis which reduce quality of life of patients. In present, potent antiretroviral therapies HAART (highly active antiretroviral therapy) has improved the length and quality of life which may lead to an increased prevalence of anterior segment ocular disorders. Read More

Graefes Arch Clin Exp Ophthalmol 2018 Jan 9;256(1):193-198. Epub 2017 Nov 9.

Department of Ophthalmology, University General Hospital of Heraklion, Crete, Greece.

Purpose: The evaluation of a non-invasive detection method for human papilloma virus (HPV) in ophthalmic pterygia.

Methods: Cotton swab samples and corresponding tissue specimens were collected from 21 ophthalmic pterygia of 21 patients. HPV detection and typing were performed by real-time PCR. Read More

Ophthalmic Plast Reconstr Surg 2018 Jan/Feb;34(1):e1-e3

Department of Ophthalmology and Visual Sciences, and Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.

A 45 year-old woman presented with blurred vision and irritation of the left eye. Clinical examination revealed a superior palpebral conjunctival lesion consistent with a diagnosis of papilloma. She was lost to follow up despite repeated attempts to schedule a biopsy, and presented again after an extended period with bilateral disease. Read More

Laryngoscope 2018 01 13;128(1):3-9. Epub 2017 Apr 13.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.

Objectives: Sinonasal inverting papilloma (IP) is a benign but locally aggressive mucosal neoplasm with a high recurrence rate. Extension into the frontal sinus presents surgical challenges for endonasal resection. This study presents an orbitofrontal approach for managing extensive IP. Read More

Can J Ophthalmol 2017 Feb 16;52(1):e30-e31. Epub 2016 Nov 16.

Laboratoire de Pathologie Clinique et Expérimentale, Hôpital Pasteur, Nice, France.

Eye Contact Lens 2018 Sep;44 Suppl 1:S77-S81

Departments of Ophthalmology (H.Y., M.D., T.Y., S.D., Y.S., J.S.), and Pathology and Laboratory Medicine (J.M., Y.T.), Ichikawa General Hospital, Tokyo Dental College, Chiba, Japan; and Department of Ophthalmology (H.Y., M.D., K.T.), Keio University School of Medicine, Tokyo, Japan.

Purpose: To investigate the association between recurrence of conjunctival papillomas and presence of atypical epithelial changes in patients undergoing surgical excision for conjunctival papilloma.

Methods: We retrospectively reviewed 1,195 ophthalmic pathology specimens from 2004 to 2014 at Ichikawa General Hospital. Pathologic specimens of 5 patients with a final diagnosis of "conjunctival papilloma" were stained with hematoxylin-eosin, Ki 67, p53, human papillomavirus (HPV) 16 and 18 antibodies. Read More

Indian J Ophthalmol 2016 Oct;64(10):778-780

Department of Ophthalmology, Sankara Eye Hospital, Ludhiana, Punjab, India.

A 2-year-old boy presented with a recurrent strawberry-like reddish mass arising from the left caruncular region for 8 months. An incisional biopsy was performed elsewhere 2 months earlier, followed by an increase in size of mass, significant epiphora, and intermittent bleeding. On examination, exuberant exophytic gelatinous mass with multifocal origin was observed arising from inferior forniceal conjunctiva and caruncle. Read More

Dis Aquat Organ 2016 Oct;121(3):233-240

Laboratório ECOPESCA - Biologia do Nécton e Ecologia Pesqueira, Departamento de Biologia Marinha, Pós Graduação em Biologia Marinha e Ambientes Costeiros, Instituto de Biologia, Universidade Federal Fluminense, 24001-970 Niterói, Rio de Janeiro, Brazil.

Fibropapillomatosis (FP) is a multifactorial disease that affects all species of marine turtles, including green turtles Chelonia mydas (Linnaeus, 1758). It is characterised by the development of internal or external tumours that, depending on their locations and sizes, may intensely impact the health condition of sea turtles. The goal of this study was to characterise the disease in C. Read More

Am J Clin Pathol 2016 Mar;145(3):385-92

From the Henry C. Witelson Ocular Pathology Laboratory, McGill University, Montreal, Canada;

Objectives: The aim of this study was to evaluate heat shock protein 90 (HSP90) expression in squamous lesions (SLs) and to assess its diagnostic value for different lesions within the SL spectrum.

Methods: A total of 70 conjunctival SLs, including 19 papillomas, 22 cases of conjunctival intraepithelial neoplasia (ConINs) I, 11 cases of ConIN II, six cases of ConIN III, and 12 squamous carcinomas (sqCAs), were evaluated using the German immunoreactive score against HSP90.

Results: Cytoplasmic HSP90 expression differed between low- and high-grade lesions (P < . Read More

Ophthalmology 2015 Nov;122(11):2154

Department of Ophthalmology and Visual Sciences, University of Wisconsin - Madison, Madison, Wisconsin.

Diagn Pathol 2015 Sep 24;10:175. Epub 2015 Sep 24.

Department of Pathology, University of California San Diego and VA San Diego Healthcare System, San Diego, CA, USA.

Background: p16 expression is a well established biomarker of cervical dysplasia and carcinoma arising from high risk human papilloma virus infection. Increased p16 expression is also seen in squamous neoplasms arising at other sites, including head, neck, and oropharyngeal tract. Squamous lesions are also frequently encountered at ocular surface and peri-orbital skin sites, but the prevalence of increased p16 expression in these lesions has been poorly studied. Read More

Asian Pac J Cancer Prev 2015 ;16(10):4265-9

Ophthalmology, Medical School, Gulhane Military Medical Academy, Ankara, Turkey E-mail :

Introduction: The aim of the study was to explore the distribution of eyelid tumors in Ankara, the capital city of Turkey, from a histopathological point of view.

Materials And Methods: Medical records of 1,502 patients who had eyelid surgery because of tumoral lesions were retrospectively reviewed after obtaining institutional review board approval. A total of 1,541 lesions with histopathologic diagnosis were included. Read More

Middle East Afr J Ophthalmol 2015 Apr-Jun;22(2):230-2

Department of Internal Medicine, Medical School, University of Ioannina, Greece.

Aims: The aim was to describe the epidemiology of primary eyelid tumors over a 30-year period at the Ioannina University Eye Clinic, Greece.

Materials And Methods: This retrospective case series examined the histopathology of eyelid tumor specimens of patients treated between 1983 and 2012. Data were collected on patient age, gender, location of the lesion, extent of tumor excision and recurrence. Read More

J Med Case Rep 2014 Dec 29;8:466. Epub 2014 Dec 29.

Henry C, Witelson Ocular Pathology Laboratory, McGill University, 3775 Rue University, Room 216, Montreal, Quebec, Canada.

Introduction: Superficial epithelioma with sebaceous differentiation is a rare benign epithelial neoplasm. It usually involves the head, neck or the back of a middle-age person. To the best of our knowledge, two ocular cases have been reported in the literature. Read More

Vet Pathol 2015 Jul 28;52(4):676-80. Epub 2014 Oct 28.

The Comparative Ocular Pathology Laboratory of Wisconsin, School of Veterinary Medicine, the University of Wisconsin-Madison, Madison, WI, USA

Papillomas of the conjunctival surface in people can be of viral or nonviral origin and are found in high association with human papillomavirus. Canine conjunctival papillomas are seldom described, and published accounts have mostly been associated with canine oral papillomavirus infection. Here, we describe conjunctival squamous papillomas that do not express papillomavirus proteins and compare them with papillomavirus-associated conjunctival papillomas. Read More

Ann Otol Rhinol Laryngol 2014 Dec 18;123(12):826-30. Epub 2014 Jun 18.

Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA

Objective: This study aimed to describe the hybrid lid crease approach in conjunction with functional endoscopic sinus surgery (FESS) for lateral frontal sinus disease with orbital extension.

Study Design: Retrospective case review.

Methods: Patients undergoing hybrid lid crease approach with FESS for frontal sinus disease were reviewed retrospectively. Read More

Surv Ophthalmol 2014 Sep-Oct;59(5):540-7. Epub 2014 Jan 28.

Department of Ophthalmology, Ophthalmic Plastic Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.

A 46-year-old woman was evaluated for a "recurring papilloma" of the left medial upper eyelid margin. Beneath the papillary lesion medial to the punctum was a 5-mm diameter cutaneous mass thought to be cystic. After excisional biopsy, histopathologic analysis documented the presence of an epidermal keratinizing squamous papilloma surmounting a circumscribed dermal papillary hidradenoma composed of deeply eosinophilic columnar cells. Read More

Trop Med Int Health 2013 Dec 30;18(12):1424-43. Epub 2013 Oct 30.

Department of Ophthalmology, University of Nairobi, Nairobi, Kenya; London School of Hygiene and Tropical Medicine, London, UK.

Objectives: To describe the epidemiology and an aetiological model of ocular surface squamous neoplasia (OSSN) in Africa.

Methods: Systematic and non-systematic review methods were used. Incidence was obtained from the International Agency for Research on Cancer. Read More

Ophthalmic Plast Reconstr Surg 2013 Nov-Dec;29(6):454-7

*Orbital Oncology and Ophthalmic Plastic Surgery Program, Department of Plastic Surgery, †Department of Radiation Oncology, and ‡Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, U.S.A.

Purpose: To determine the rates of globe-sparing treatment and useful final visual function in patients with primary lacrimal sac/nasolacrimal duct carcinomas treated with multidisciplinary therapy.

Methods: The medical records of 14 patients with primary lacrimal sac/nasolacrimal duct carcinoma treated at 1 institution were retrospectively reviewed.

Results: The patients were 9 men and 5 women; the median age at diagnosis was 58. Read More

Middle East Afr J Ophthalmol 2013 Jul-Sep;20(3):187-92

Ophthalmic Research Center, Shahid Beheshti Medical University, Department of Ophthalmology, Labbafinejad Hospital, Tehran, Iran.

Purpose: The purpose of this study was to evaluate the demographics and clinical features of eyelid masses in a tertiary eye hospital over a 10-year period.

Materials And Methods: A retrospective chart review was performed for patients admitted with eyelid tumors from 2000 to 2010. Data were collected and analyzed on the demographic features, location of the tumor, types of treatment, and pathologic findings. Read More

Zhonghua Yan Ke Za Zhi 2013 Jan;49(1):37-40

Henan Eye Institute, Henan Key Laboratory of Keratonosus, Zhengzhou 450003, China.

Objective: To analyze the pathological classification of ocular tumor in children.

Methods: 213 cases (214 eyes) of ocular tumor in children below 14 years old between January 2001 and December 2007 in Henan Eye Institute were reviewed retrospectively, the pathological classification were made according to the location and nature of the tumor.

Results: There were 17 eyes (7. Read More

J Biomed Res 2012 Nov 4;26(6):474-7. Epub 2012 Apr 4.

Department of Dermatology, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China;

A 55-year-old Chinese man presented with an asymptomatic pedunculated elevation on his left lower eyelid which had been gradually increasing in size during the past three years. The patient was diagnosed with eyelid papilloma by pathological examination. Concomitantly, the patient developed open comedones with a bilateral linear distribution, along with oblique wrinkle lines in his infraorbital regions. Read More

Can J Ophthalmol 2012 Dec 25;47(6):e47-8. Epub 2012 Sep 25.

Vet Ophthalmol 2013 Jul 9;16 Suppl 1:105-12. Epub 2012 Aug 9.

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

A 6-year-old female spayed Chihuahua was presented for the evaluation of generalized pigmented cutaneous masses, one of which was present on the lower right eyelid. The dog was not on immunosuppressive medications and did not have historical or laboratory evidence of underlying endocrine disease, including hypothyroidism and hyperadrenocorticism. Histopathology, immunohistochemistry, and polymerase chain reaction of a cutaneous biopsy from the left antebrachium containing representative lesions confirmed viral papillomatosis. Read More

BMJ Case Rep 2012 May 8;2012. Epub 2012 May 8.

Allergy and Clinical Immunology, University of Torino and AO Ordine Mauriziano, Torino, Italy.

A 17-year-old girl reported generalised urticaria, eyelid angioedema, rhino-conjunctivitis, dyspnoea and wheezing 1 h after third intramuscular administration of quadrivalent human papilloma virus vaccine (Gardasil). She was treated with antihistamine, and corticosteroids with prompt relief of rhinitis and dyspnoea, while urticaria and angioedema lasted 24 h. Intradermal test with Gardasil, which contains polysorbate 80 (PS80), resulted positive, while skin tests with the bivalent vaccine were negative. Read More

Niger J Clin Pract 2012 Jan-Mar;15(1):89-92

Department of Pathology, University College Hospital, Ibadan, Nigeria.

Background: There is very limited literature on squamous papillomas of the conjunctiva from Nigeria and sub-Saharan Africa. In an attempt to contribute to the literature on the subject, we studied the clinicopathological characteristics of patients histologically diagnosed with squamous papilloma of the conjunctiva in Ibadan, Nigeria.

Materials And Methods: Clinical and pathological records of patients with histological diagnosis of squamous papilloma of the conjunctiva made in the Department of Pathology, University College Hospital, Ibadan, between January 1985 and December 2004, were reviewed. Read More

Eye Sci 2011 Sep;26(3):148-53

Sun Yat-sen University, Guangzhou, China.

Purpose: Corneal tumors are rare in clinical practice. There was a paucity of data on the incidence of various corneal tumors, their clinical and pathological features and surgical management, especially on large patient samples.

Methods: The medical records of 39 patients with corneal tumors referred to Zhongshan Ophthalmic Center, Sun Yat-sen University, China from Jan 1,1996 to Dec 31,2002 were reviewed retrospectively. Read More

Cutan Ocul Toxicol 2012 Mar 2;31(1):77-80. Epub 2011 Sep 2.

Department of Ophthalmology, Hospital of Navarra, Pamplona, Spain.

Context: Ethyl chloride (EC) is a fast-acting vapo-coolant spray that provides rapid, transient, local analgesia for minor invasive procedures. Although the application of EC has decreased, it can be used as a cryoanalgesic agent in minor surgical procedures.

Objective: Despite the widespread use of EC as a local anesthetic, there are few reported cases of serious adverse side effects. Read More

Jpn J Ophthalmol 2011 Nov 24;55(6):660-9. Epub 2011 Aug 24.

Department of Ophthalmology and Visual Sciences, Faculty of Medicine, Yamagata University, 2-2-2 Iida-nishi, Yamagata, Yamagata 990-9585, Japan.

Purpose: The conjunctiva maintains the health of the ocular surface by protecting the eye from pathogen invasion, injury, and dryness. In this study, we investigated the regulation of hyaluronan (HA) synthesis by cytokines in conjunctiva-derived cells.

Methods: Cultured primary cells derived from human conjunctivas that had been removed as surgical specimens were transfected with an immortalizing gene (human papilloma virus 16 E6/E7). Read More

Ophthalmic Plast Reconstr Surg 2012 Mar-Apr;28(2):e47-8

Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.

Eyelid margin papillomas are challenging because complete excision may be cosmetically unacceptable. Interferon has been previously reported as an effective treatment for conjunctival papillomas. We report successful treatment of a large upper eyelid margin papilloma with intralesional interferon. Read More

Breast Cancer 2014 Mar 3;21(2):231-5. Epub 2010 Nov 3.

Department of Breast Surgery, Shizuoka Cancer Center Hospital, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka, 411-8777, Japan,

IgG4-related sclerosing disease was first identified and defined in the twenty-first century. In this pathology, the serum IgG4 level increases and IgG4-positive plasma cells and lymphocytes infiltrate organs such as the pancreas, salivary glands, lacrimal glands, kidneys, and the retroperitoneum. Presented in this report is a case of IgG4-related sclerosing disease that occurred in the breast and was treated successfully with steroid therapy. Read More

Ophthalmic Plast Reconstr Surg 2010 Nov-Dec;26(6):448-9

Eye Research Center, Farabi Eye Hospital, Department of Ophthalmology, Medical School, Medical Sciences/Tehran University, Tehran, Iran.

Purpose: To describe a technique for excisional biopsy of eyelid papillomatous lesions using a radiofrequency (RF) unit.

Method: In this prospective, interventional case series, 64 patients with eyelid papillomatous lesions underwent excisional biopsy using an RF unit.

Results: The upper eyelid was involved in 34. Read More

Pathol Oncol Res 2010 Dec 8;16(4):609-12. Epub 2010 Apr 8.

Department of Pathology, Indiana University, 350 W 11th Street, CPL 4010, Indianapolis, IN 46202, USA.

Conjunctival squamous cell carcinoma (SCC) is a rare finding in everyday clinical practice, but is the most common malignancy of the ocular surface. The incidence of this malignancy in the United States is 0.03 per 100,000 persons. Read More

Klin Oczna 2009 ;111(10-12):319-22

Z Kliniki Okulistycznej Wojskowego Instytutu Medycznego w Warszawie.

Purpose: Analysis of causes of epiphora in patients which have been examined in Department of Ophthalmology in Military Institute of Health Service from 2004 to 2007.

Material And Methods: The study has comprised 330 subjects: 241 women and 89 men (mean age 58.85 +/- 19. Read More

Korean J Ophthalmol 2009 Dec 4;23(4):306-8. Epub 2009 Dec 4.

Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, #134 Sinchon-dong, Seodaemun-gu, Seoul, Korea.

Seborrheic keratosis is a benign epithelial neoplasia that occurs mainly in the skin of the eyelids and face. We describe a case of seborrheic keratosis of the conjunctiva confirmed by histopathology. A 72-year-old man presented with a recurrent conjunctival mass involving the nasal side of his right eye. Read More

Ophthalmic Plast Reconstr Surg 2009 Sep-Oct;25(5):413-4

Department of Ophthalmology, College of Medicine, Dong-A University, Busan, Korea.

Absorbable plugs are used before attempting permanent occlusion to observe whether the patient will be amenable to treatment for dry eye. Little is known about the complications of absorbable plugs. The authors present a case of canaliculitis with a papilloma-like mass caused by long-standing unabsorbed collagen plug that had been placed 3 years earlier. Read More

Hum Pathol 2009 Dec 5;40(12):1813-9. Epub 2009 Sep 5.

Department of Pathology, Creighton University Medical Center, Omaha, NE 68131, USA.

Multiple renal tumors of diverse morphology are rare and typically seen in Birt-Hogg-Dubé syndrome. Birt-Hogg-Dubé syndrome is a rare inherited cancer syndrome caused by a germline mutation in the folliculin (FLCN) gene, but the genetic causes for histologic diversity of renal tumors in Birt-Hogg-Dubé syndrome have not been elucidated. We describe here a 64-year-old man with a novel germline mutation in the FLCN gene who presented with 3 phenotypically distinct renal tumors in the same kidney, which were histologically classified as oncocytoma (1. Read More

Arch Dermatol 2009 Aug;145(8):944-7

Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark.

Am J Dermatopathol 2009 May;31(3):256-62

Laboratoire d'Ophtalmopathologie, Hôpital Ophtalmique Jules Gonin, Lausanne, Suisse.

Eyelid tumors are the most common neoplasm in daily ophthalmology practice and encompass a wide variety of benign and malignant tumors. In this retrospective study, we report the clinical and histological features of 5504 eyelid skin tumors diagnosed at the Laboratory of Ophthalmopathology of the Hôpital Ophtalmique Jules Gonin, Lausanne, Switzerland, between January 1989 and December 2007. Benign tumors largely predominated over malignant ones, representing 84% of cases in this series, and the 5 most frequent subtypes were squamous cell papilloma (26%), seborrheic keratosis (21%), melanocytic nevus (20%), hidrocystoma (8%), and xanthoma/xanthelasma (6%). Read More

Nepal J Ophthalmol 2009 Jan-Jun;1(1):9-12

Departments of Ophthalmology, B P Koirala Institute of Health Sciences, Dharan, Nepal.

Background: ocular tumors are commonly encountered in ophthalmic practice.

Objective: to study the clinical pattern of ocular tumors in the eastern region of Nepal.

Materials And Methods: the hospital records of patients with ocular tumors treated at B P Koirala Institute of Health Sciences in the eastern region of Nepal over a period of 5 years (April 2003 - March 2008) were studied retrospectively. Read More