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    Intra cranial Cryptococcoma - Clinicopathological correlation and surgical outcome-a single institute experience.
    World Neurosurg 2018 Apr 17. Epub 2018 Apr 17.
    Department of Neuro Microbiology, National Institute of Mental Health and Neurosciences, Bangalore, India.
    Objective: The present case series describes the clinical characteristics of patients diagnosed with intra cranialcryptococcoma(ICC), the clinic-pathological correlation and the outcomes following surgery.

    Materials And Methods: The clinical data were collected from hospital case records and pathological confirmation was done by a neuropathologist. Clinical details, imaging features, and treatment modalities were studied and were correlated with outcomes based on regular follow up. Read More

    Papilledema revisiting after sinus angioplasty of chronic cerebral venous sinus thrombosis.
    Indian J Ophthalmol 2018 May;66(5):714-717
    Department of Ophthalmology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
    This case series aimed to review the significance of revisiting papilledema after successful cerebral venous sinus thrombosis (CVST) management with sinus angioplasty. Four patients presented with blurring and transient obscuration of vision with papilledema, headache, tinnitus, and vomiting. On magnetic resonance venography and digital subtraction angiography, chronic transverse sinus thrombosis was diagnosed for which patients underwent endovascular intervention (stenting). Read More

    Fluvoxamine-induced intracranial hypertension in a 10-year-old boy.
    Indian J Ophthalmol 2018 May;66(5):712-714
    Department of Pediatric Ophthalmology, Sir J. J. Hospital and Grant Medical College, Mumbai, Maharashtra, India.
    Drug-induced intracranial hypertension is a well-established entity. We report a rare case of intracranial hypertension with papilledema in a 10-year-old boy following use of fluvoxamine, a selective serotonin reuptake inhibitor. On discontinuing the drug, the papilledema resolved over 4 months without any residual visual anomalies. Read More

    Syphilis-Related Eye Disease Presenting as Bilateral Papilledema, Retinal Nerve Fiber Layer Hemorrhage, and Anterior Uveitis in a Penicillin-Allergic Patient.
    Case Rep Infect Dis 2018 18;2018:2840241. Epub 2018 Feb 18.
    University of Nebraska Medical Center, S. 42nd and Emile St., Omaha, NE, USA.
    . is known as the "great masquerader" for its many presentations and ocular findings in patients who are infected and develop secondary and tertiary stage of syphilis. Syphilitic ocular manifestations include uveitis, chorioretinitis, retinitis, vasculitis, vitritis, and panuveitis all with or without decreased visual acuity. Read More

    The Frozen Brain State of Cryptococcus gattii: A Globe-Trotting, Tropical, Neurotropic Fungus.
    Neurocrit Care 2018 Apr 16. Epub 2018 Apr 16.
    Neurosurgery Department, Kaiser Sacramento, 2025 Morse Avenue, Sacramento, CA, 95825, USA.
    Initially reported in tropical regions, Cryptococcus gattii infection is now diagnosed globally.

    Methods: case report; Literature review. Although initial reports described outbreaks of pulmonary and central nervous system (CNS) disease in tropical regions such as Australia and New Guinea, it is now clear that Cryptococcus gattii is a global, neurotropic pathogen. Read More

    Optic disc drusen: understanding an old problem from a new perspective.
    Acta Ophthalmol 2018 Apr 16. Epub 2018 Apr 16.
    Department of Clinical Neurosciences, University of Calgary, Calgary, Canada.
    Optic disc drusen (ODD) are acellular deposits located in the optic nerve head of up to 2.4% of the population. They may develop as by-products of impaired axonal metabolism in genetically predisposed individuals, in whom a narrow scleral canal is hypothesized to play a role. Read More

    Pseudotumor cerebri in kaposiform lymphangiomatosis: a case report and pathogenetic hypothesis.
    Childs Nerv Syst 2018 Apr 13. Epub 2018 Apr 13.
    Regional Service of Neurosurgery, Virgen de la Arrixaca University Hospital, 30120, Murcia, Spain.
    Case Report: A 4-year-old boy with kaposiform lymphangiomatosis (KLA) developed progressive headaches and papilloedema and was diagnosed with pseudotumor cerebri initially treated with acetazolamide. Clinical deterioration prompted placement of a ventriculoperitoneal shunt. After the surgery, the child's condition has markedly improved. Read More

    Ambiguity in the Dural Tail Sign on MRI.
    Surg Neurol Int 2018 19;9:62. Epub 2018 Mar 19.
    Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.
    Background: Meningiomas give rise to the dural tail sign (DTS) on contrast-enhanced magnetic resonance imaging (CEMRI). The presence of DTS does not always qualify for a meningioma, as it is seen in only 60-72% of cases. This sign has been described in various other lesions like lymphomas, metastasis, hemangiopericytomas, schwannomas and very rarely glioblastoma multiforme (GBM). Read More

    Chiari malformation and tuberculous meningitis: aetiology and management.
    BMJ Case Rep 2018 Apr 5;2018. Epub 2018 Apr 5.
    Department of Neurosciences, University of the Philippines-Philippine General Hospital, Manila, Philippines.
    This is the first reported case of a Chiari 1 malformation in association with tuberculous (TB) meningitis. We present a case of a 23-year-old woman with a 2-week history nocturnal fever, vertigo, headache and projectile vomiting. She had nystagmus, scanning speech, bilateral papilloedema and ataxia. Read More

    Pseudotumor cerebri as the presentation of Lyme disease in a non-endemic area.
    BMJ Case Rep 2018 Mar 30;2018. Epub 2018 Mar 30.
    Department of Pediatria, Hospital Professor Doutor Fernando Fonseca, EPE, Amadora, Portugal.
    Intracranial hypertension is a rare entity in prepubertal children, and its differential diagnosis includes a number of systemic diseases, drugs, vitamin deficiencies and excesses, and hereditary conditions. Infectious aetiology is rare. The case of a 9-year-old boy with intracranial hypertension secondary to acute neuroborreliosis is described. Read More

    Retinal Vessel Diameters Change Within 1 Hour of Intracranial Pressure Lowering.
    Transl Vis Sci Technol 2018 Mar 19;7(2). Epub 2018 Mar 19.
    Department of Ophthalmology, University of Southern California, Los Angeles, CA, USA.
    Purpose: We tested the hypotheses that retinal venule diameter (Dv) is associated with baseline intracranial pressure (ICP) level and that Dv is reduced shortly after ICP lowering.

    Methods: Dv and arteriole diameter (Da) were extracted from scanning laser ophthalmoscopic images in 40 eyes of 20 adult human subjects (10 with and 10 without papilledema) immediately before and after measurement of ICP (range, 10-55 cm HO) and ICP lowering by cerebrospinal fluid (CSF) drainage via lumbar puncture (LP). Generalized estimating equations (GEE) modeled the relationship between baseline ICP, Da and Dv before LP. Read More

    Papilloedema and Autoimmune Retinopathy from Systemic Lupus Erythematosus.
    Neuroophthalmology 2018 Apr 18;42(2):117-121. Epub 2017 Aug 18.
    Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.
    A 33-year-old female presented with bilateral papilloedema and constricted visual fields from autoimmune retinopathy. She then developed a painful peripheral neuropathy that led to further work-up and the diagnosis of systemic lupus erythematosus. Papilloedema and autoimmune retinopathy from systemic lupus erythematosus is a unique presentation. Read More

    Weight reduction for a better visual outcome in idiopathic intracranial hypertension.
    Arq Bras Oftalmol 2018 Jan-Feb;81(1):18-23
    Izmir Ataturk Education and Research Hospital, Turkey.
    Purpose: To evaluate the correlation between weight reduction and visual outcome in overweight patients with idiopathic intracranial hypertension.

    Methods: Thirty-nine newly diagnosed, overweight (body mass index >25 kg/m2) patients with idiopathic intracranial hypertension were studied retrospectively. All patients underwent medical treatment with acetazolamide, and a weight reduction program was also offered. Read More

    The importance of specific rehabilitation for an obese patient with idiopathic intracranial hypertension: a case report.
    Int J Rehabil Res 2018 Mar 13. Epub 2018 Mar 13.
    Headache and Neuroalgology Unit.
    Idiopathic intracranial hypertension (IIH) is associated with obesity, and weight loss is important to reduce intracranial pressure and improve visual function. A 38-year-old woman with IIH followed an extreme diet, which resulted in 30% weight loss (BMI moved from 34.9 to 24. Read More

    Primary normocephalic pancraniosynostosis detected incidentally after an accidental head injury: a case report and review of the literature.
    Childs Nerv Syst 2018 Mar 13. Epub 2018 Mar 13.
    Department of Diagnostic Imaging, National University Health System, 1E Kent Ridge Rd, Singapore, 119228, Singapore.
    Objective: Majority of multi-suture craniosynostosis are related to single-gene disorders or chromosomal abnormalities. Children with craniosynostosis usually present at an early age due to the presence of an abnormal head shape, with the exception of a unique entity termed primary normocephalic pancraniosynostosis. The objective of this article is to describe an unusual case of primary normocephalic pancraniosynostosis, detected incidentally following an accidental head injury. Read More

    Disease and Treatment-Related Sequelae in Patients with Complex Jugulotympanic Paraganglioma.
    J Clin Med 2018 Mar 10;7(3). Epub 2018 Mar 10.
    Department of ENT, Klinikum Dortmund, 44145 Dortmund, Germany.
    Background: Jugulotympanic paraganglioma (JTP) are benign, high-vascularized lesions that frequently invade the jugular foramen, temporal bone, the upper neck, and the posterior fossa cavity, resulting in a wide variety of clinical symptoms.

    Methods: In this retrospective study, we assess the clinical symptoms and discuss the individual multidisciplinary treatment and outcome of 22 patients with JTP.

    Results: In 12 patients, a hearing deficit was the presenting symptom, whereas pulsatile tinnitus and otalgia were present in six and four patients respectively. Read More

    Intracranial pressure in patients with papilloedema.
    Acta Neurol Scand 2018 Mar 12. Epub 2018 Mar 12.
    Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
    Objectives: Papilloedema is a clinical manifestation of chronically raised intracranial pressure (ICP), often seen in idiopathic intracranial hypertension (IIH). However, the extent of intracranial hypertension required to produce papilloedema is not known. We compare ICP values in IIH patients who developed papilloedema and those who did not. Read More

    Headache in Guillain-Barré Syndrome: Diagnostic and Management Implications.
    Can J Neurol Sci 2018 Mar;45(2):240-242
    Department of Medicine,Division of Neurology,University of Alberta,Edmonton,Alberta,Canada.
    Headache is an uncommon symptom in Guillain-Barré syndrome (GBS). We review four clinical settings related to GBS in which headache may be present. We focus on pathophysiological explanations, alerting the clinician to further potential investigations and treatment. Read More

    Cranial morcellation decompression for refractory idiopathic intracranial hypertension in children.
    Childs Nerv Syst 2018 Mar 3. Epub 2018 Mar 3.
    Division of Pediatric Neurosurgery, Department of Surgery and Anatomy, University Hospital, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049-900, Brazil.
    Background: Primary idiopathic intracranial hypertension (PIIH) in children is rare and has a poorly understood pathophysiology. It is characterized by raised intracranial pressure (ICP) in the absence of an identified brain lesion. Diagnosis is usually confirmed by the measurement of a high cerebrospinal fluid (CSF) opening pressure and exclusion of secondary causes of intracranial hypertension. Read More

    Positron emission tomography/computed tomography scan of Vogt-Koyanagi-Harada syndrome with associated autoimmune thyroid disease: A case report and literature review.
    Medicine (Baltimore) 2018 Mar;97(9):e0047
    Department of Ophthalmology, Tri-Service General Hospital.
    Rationale: Vogt-Koyanagi-Harada (VKH) syndrome is a rare disease and could be associated with autoimmune thyroid disease (AITD). This report was aimed to investigate the utility of F-fludeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) for the diagnosis of VKH syndrome with AITD and to perform a literature review on the association between the 2 diseases.

    Patient Concerns: A 55-year-old woman without the history of ocular trauma suffered from chronic headache. Read More

    Surgical management of colloid cysts in children: experience at a tertiary care center.
    Childs Nerv Syst 2018 Feb 27. Epub 2018 Feb 27.
    Department of Neurosurgery, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, 560029, India.
    Introduction: Colloid cysts are uncommon lesions in the pediatric age group, which most commonly occur in the fourth through fifth decades. The authors hereby report a series of 36 patients with colloid cysts in the pediatric age group.

    Material And Method: A retrospective chart review was conducted on all patients with colloid cyst who underwent surgery in our institute between November 2003 and December 2016 (13 years). Read More

    Improvement of Color Vision Following Posterior Cranial Vault Distraction for Crouzon Syndrome.
    J Craniofac Surg 2018 Feb 26. Epub 2018 Feb 26.
    Department of Plastic Surgery, Medical College of Wisconsin, Milwaukee, WI.
    Crouzon syndrome (CS) is one of the craniosynostosis syndromes that leads to early fusion of cranial sutures and increased intracranial pressure. Intracranial hypertension is a serious complication that may lead to vision loss and cognitive impairment. Early detection and management are necessary to prevent complications. Read More

    Optic Nerve Head and Macular Optical Coherence Tomography Measurements in Papilledema Compared With Pseudopapilledema.
    J Neuroophthalmol 2018 Feb 22. Epub 2018 Feb 22.
    Eye Research Center (MAF, SO, SM), Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran; Department of Ophthalmology (SM), University of California, San Francisco, San Francisco, California; and Department of Ophthalmology (PSS), University of Colorado School of Medicine, Aurora, Colorado.
    Background: To compare macular and optic nerve head optical coherence tomography (OCT) measurements in mild to moderate papilledema and pseudopapilledema.

    Methods: One hundred nineteen eyes of 61 patients with mild to moderate papilledema, 84 eyes of 48 patients with pseudopapilledema, and 60 eyes of 60 healthy normal individuals were enrolled in this cross-sectional study. Using Spectralis SD-OCT, macular scans with macular ganglion cell-inner plexiform layer (GCIPL) and macular retinal nerve fiber layer (RNFL) segmentation were performed and divided into 2 regions (inner and outer, with a diameter of 3 and 6 mm, respectively); in addition, Bruch membrane opening (BMO) area and peripapillary RNFL thickness were obtained. Read More

    Ventriculoperitoneal shunt treatment in a pregnant renal transplant recipient with idiopathic intracranial hypertension: Case report and review of the literature.
    Neurol Neurochir Pol 2018 Feb 6. Epub 2018 Feb 6.
    Akdeniz University School of Medicine, Obstetrics and Gynecology Department, Antalya, Turkey.
    Idiopathic intracranial hypertension (IIH) is a relatively uncommon disorder characterised by raised intracranial pressure without an established pathogenesis. Diagnosis of IIH requires the demonstration of symptoms and signs referable only to elevated intracranial pressure; cerebrospinal fluid (CSF) opening pressure >25cm HO measured in the lateral decubitus position; normal CSF composition; and no evidence for an underlying structural cause demonstrated by using MRI or contrast-enhanced CT scan for typical patients and MRI and MR venography for atypical patients such as man, children and those with low body mass index. We present a 38-year old primigravid renal transplant patient at 7 weeks of gestation who presented with 2 weeks of intense, throbbing, holocranial headache, nausea, vomiting, photophobia, diplopia and progressive visual loss. Read More

    Trapped ventricle after laser ablation of a subependymal giant cell astrocytoma complicated by intraventricular gadolinium extravasation: case report.
    J Neurosurg Pediatr 2018 Feb 16:1-5. Epub 2018 Feb 16.
    Division of Pediatric Neurosurgery and.
    Magnetic resonance imaging-guided stereotactic laser ablation of intracranial targets, including brain tumors, has expanded dramatically over the past decade, but there have been few reports of complications, especially those occurring in a delayed fashion. Laser ablation of subependymal giant cell astrocytomas (SEGAs) is an attractive alternative to maintenance immunotherapy in some children with tuberous sclerosis complex (TSC); however, the effect of treatment on disease progression and the nature and frequency of potential complications remains largely unknown. The authors report the case of a 5-year-old boy with TSC who underwent stereotactic laser ablation of a SEGA at the right foramen of Monro on 2 separate occasions. Read More

    Life-Threatening Headaches in Children: Clinical Approach and Therapeutic Options.
    Pediatr Ann 2018 Feb;47(2):e74-e80
    Life-threatening headaches in children can present in an apoplectic manner that garners immediate medical attention, or in an insidious, more dangerous form that may go unnoticed for a relatively long period of time. The recognition of certain clinical characteristics that accompany the headache should prompt recognition and referral to an institution equipped with neuroimaging facilities, pediatric neurosurgeons, and neurologists. Thunderclap headaches, which reach a peak within a very short period of time, may be the presenting feature of conditions such as arterial dissection, venous sinus thrombosis, and reversible cerebral vasoconstriction syndrome, which can be addressed by specific pharmacological options instituted in an intensive care setting. Read More

    Pediatric Intracranial Hypertension: a Current Literature Review.
    Curr Pain Headache Rep 2018 Feb 13;22(2):14. Epub 2018 Feb 13.
    Department of Ophthalmology, Nationwide Children's Hospital, Columbus, OH, USA.
    Purpose Of Review: The purpose of this review is to provide an update on pediatric intracranial hypertension.

    Recent Findings: The annual pediatric incidence is estimated at 0.63 per 100,000 in the USA and 0. Read More

    Characterization of Retinal Ganglion Cell and Optic Nerve Phenotypes Caused by Sustained Intracranial Pressure Elevation in Mice.
    Sci Rep 2018 Feb 12;8(1):2856. Epub 2018 Feb 12.
    Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.
    Elevated intracranial pressure (ICP) can result in multiple neurologic sequelae including vision loss. Inducible models of ICP elevation are lacking in model organisms, which limits our understanding of the mechanism by which increased ICP impacts the visual system. We adapted a mouse model for the sustained elevation of ICP and tested the hypothesis that elevated ICP impacts the optic nerve and retinal ganglion cells (RGCs). Read More

    Complications of Optic Nerve Sheath Fenestration as a Treatment for Idiopathic Intracranial Hypertension.
    Semin Ophthalmol 2018 ;33(1):36-41
    a Department of Neuro-Ophthalmology , Massachusetts Eye & Ear, Harvard Medical School , Boston , MA , USA.
    There are a number of surgical options for treatment of idiopathic intracranial hypertension (IIH) when it is refractory to medical treatment and weight loss. Optic nerve sheath fenestration (ONSF) is one of these options. Use of this procedure varies among centers due to experience with the procedure and concern for associated complications that can result in severe loss of vision. Read More

    Long-term visual outcome in a Danish population of patients with idiopathic intracranial hypertension.
    Acta Ophthalmol 2018 Feb 6. Epub 2018 Feb 6.
    Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
    Purpose: Idiopathic intracranial hypertension (IIH) is characterized by raised intracranial pressure (ICP), normal cerebrospinal composition and exclusion of alternative causes to increased ICP. The aim of this study was to evaluate long-term visual outcome in a Danish population of IIH patients.

    Methods: Retrospective chart review of 41 women diagnosed with IIH between June 2007 and March 2013. Read More

    Forgetting the fundoscope - A case of fulminant idiopathic intracranial hypertension causing rapid visual loss.
    J Clin Neurosci 2018 Apr 1;50:108-110. Epub 2018 Feb 1.
    Neurology Department, Auckland City Hospital, Auckland, New Zealand.
    Idiopathic intracranial hypertension (IIH) is a syndrome of elevated intracranial pressure without evidence of intracranial mass lesion or venous thrombosis, and bland cerebrospinal fluid examination. It mostly affects overweight women of childbearing age and if left untreated, can lead to permanent visual loss. Visual decline in this condition is generally slow, over months to years. Read More

    Treatment of idiopathic intracranial hypertension via stereotactic placement of biventriculoperitoneal shunts.
    J Neurosurg 2018 Feb 2:1-9. Epub 2018 Feb 2.
    Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah; and.
    OBJECTIVE Idiopathic intracranial hypertension (IIH), or pseudotumor cerebri, is a complex and difficult-to-manage condition that can lead to permanent vision loss and refractory headaches if untreated. Traditional treatment options, such as unilateral ventriculoperitoneal (VP) or lumboperitoneal (LP) shunt placement, have high complication and failure rates and often require multiple revisions. The use of bilateral proximal catheters has been hypothesized as a method to improve shunt survival. Read More

    Factors Influencing the Incidence of Papilledema in Patients with Cerebral Venous Thrombosis.
    Adv Biomed Res 2017 26;6:165. Epub 2017 Dec 26.
    Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
    Background: Cerebral venous thrombosis (CVT) is an uncommon cerebrovascular disease with a wide spectrum of symptoms and severity. This study analyzes the factors influencing the incidence of papilledema in patients with cerebral venous thrombosis.

    Materials And Methods: In this research 65 patients with CVT were examined between 2011 and 2013, and the patients were followed up one, three, six, and twelve months after the initial diagnosis. Read More

    Resolution of unilateral sensorineural hearing loss in a pediatric patient with a severe phenotype of Muckle-Wells syndrome treated with Anakinra: a case report and review of the literature.
    J Otolaryngol Head Neck Surg 2018 Jan 30;47(1). Epub 2018 Jan 30.
    Department of Pediatric Otolaryngology Head and Neck Surgery, McGill University Health Center, Montreal Children's Hospital, 1001, boul. Décarie - Local A02.3017, Montreal, QC, H4A 3J1, Canada.
    Background: Muckle-Wells syndrome (MWS) is a rare auto-inflammatory disease characterized by the presence of recurrent urticaria, deafness and amyloidosis. Progressive sensorineural hearing loss (SNHL) is reported to occur in up to 85% of patients occurring in the second and third decades and as early as the first decade in patients with a more severe phenotype, thus potentially having a significant impact on a child's development. IL-1 inhibitors, such as Anakinra, have been described to improve systemic inflammation, and stabilize or improve hearing status as well. Read More

    Use of neuroimaging measurements of optic nerve sheath diameter to assess intracranial pressure in craniosynostosis.
    Childs Nerv Syst 2018 May 29;34(5):939-946. Epub 2018 Jan 29.
    Department of Plastic Surgery - Cleft-Craniofacial Center, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, 15224, USA.
    Purpose: This study aims to evaluate accuracy of optic nerve sheath diameter (ONSD) measurements obtained by magnetic resonance imaging (MRI) in patients with craniosynostosis (CS) for detection of high intracranial pressure (ICP) and to correlate MRI-derived ONSD measurements with those obtained by computed tomography (CT) scans in CS patients.

    Methods: A retrospective review was conducted on CS patients who had MRI- and age-matched controls with normal MRI. Diagnosis of intracranial hypertension was based on presence of papilledema, direct ICP monitoring, and/or lumbar puncture. Read More

    Vestibular Schwannoma Presenting with Bilateral Papilledema Without Hydrocephalus: Case Study.
    Cureus 2017 Nov 20;9(11):e1862. Epub 2017 Nov 20.
    Neurosurgery, Hadassah-Hebrew University Medical Center.
    Bilateral papilledema secondary to obstructive or communicating hydrocephalus in patients with vestibular schwannomas is a known presentation; however, papilledema in the absence of hydrocephalus is rarely reported and its mechanism is poorly understood. We report a case of a 20-year-old woman presenting with visual deterioration and bilateral papilledema on fundoscopy. Magnetic resonance imaging (MRI) revealed a giant vestibular schwannoma with no sign of hydrocephalus. Read More

    Visual failure and sinus thrombosis following depressed skull fracture: management with single session lumboperitoneal shunt and sinus decompression -case report.
    Br J Neurosurg 2018 Jan 24:1-5. Epub 2018 Jan 24.
    a Department of Neurosurgery , Goa Medical College , Bambolim , Goa , India.
    Elevation of a depressed skull fracture (DSF) overlying a venous sinus is generally avoided due to risk of sinus injury. Rarely, the sinus may be compressed by the fractured segment, causing intracranial hypertension (IH) or encephalopathy and can only be diagnosed with cerebral angiography or MR imaging techniques. The posterior third of the superior sagittal sinus (SSS) was found involved in all the reported cases. Read More

    Cerebral Venous Thrombosis in a Patient with Iron Deficiency Anemia and Thrombocytopenia: A Case Report.
    Open Access Maced J Med Sci 2017 Dec 28;5(7):967-969. Epub 2017 Nov 28.
    Geriatric Health Services, MOH, Kuwait.
    Aim: To report a potential association of thrombosis, thrombocytopenia with iron deficiency anaemia.

    Case Report: A 43-year-old female experienced an episode of a headache, with bilateral papilledema by neurological examination, magnetic resonance venography (MRV) brain showed cerebrovenous thrombosis (CVT), iron deficiency anaemia and thrombocytopenia by blood investigations, that was treated with iron supplementations and anticoagulation.

    Conclusion: In this patient, cerebrovenous thrombosis (CVT) was discovered in a patient with thrombocytopenia and iron deficiency anaemia and treated with iron supplements and anticoagulation, we concluded that thrombocytopenia is not a protective factor against thrombosis especially with iron deficiency anaemia. Read More

    Neuro-Ophthalmic Presentation of Neuro-Sweet Disease.
    Neuroophthalmology 2017 Aug 15;41(4):202-206. Epub 2017 Mar 15.
    Department of Neurological Sciences and Stanley Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska, USA.
    Acute febrile neutrophilic dermatosis (Sweet syndrome) is a systemic inflammatory condition usually associated with autoimmune or neoplastic processes and characterised by inflammatory dermatologic lesions such as erythematous plaques and papules associated with fever and leukocytosis. Neurological and ophthalmological involvement is rare. The authors describe an unusual case of Sweet syndrome associated with microscopic polyangiitis presenting with papilloedema, anterior uveitis, and skin rash. Read More

    Causes and Prognosis of Unilateral and Bilateral Optic Disc Swelling.
    Neuroophthalmology 2017 Aug 10;41(4):187-191. Epub 2017 Apr 10.
    Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo, Kyoto, Japan.
    The authors reviewed 93 consecutive cases with optic disc swelling (ODS) to compare clinical manifestations and prognosis among the causes. Among unilateral ODS patients ≥50 years old and without pain, anterior ischaemic optic neuropathy accounted for 87.5%. Read More

    Cerebral Venous Thrombosis with Papilloedema Secondary to Skull Base Plasmacytoma.
    Neuroophthalmology 2017 Oct 8;41(5):284-286. Epub 2017 May 8.
    Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois, USA.
    A 60-year-old woman with history of multiple myeloma was in remission after stem cell transplant 6 years prior. She was undergoing work-up for headaches that were thought to be secondary to a right mastoiditis seen on magnetic resonance imaging (MRI). On routine eye exam, papilloedema was noted. Read More

    Kikuchi-Fujimoto disease triggered by Salmonella enteritidis in a child with concurrent auto-immune thyroiditis and papilloedema.
    Paediatr Int Child Health 2018 Jan 8:1-4. Epub 2018 Jan 8.
    a Departments of Pediatrics , Dr Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital , Ankara , Turkey.
    Kikuchi-Fujimoto disease (KFD) is a histiocytic necrotising lymphadenitis characterised by painful cervical lymphadenopathy, fever, malaise and weight loss. Infections, auto-immune pathogenesis and a genetic association have been implicated. A 12-year-old boy presented with a 1-month history of fever, abdominal pain, constipation and weight loss, and a painful lymph node was detected in the right axilla. Read More

    Segmentation error in spectral domain optical coherence tomography measures of the retinal nerve fibre layer thickness in idiopathic intracranial hypertension.
    BMC Ophthalmol 2018 Jan 4;17(1):257. Epub 2018 Jan 4.
    Institute of Metabolism and Systems Research, University of Birmingham, B15 2TT, Birmingham, UK.
    Background: Optical Coherence Tomography (OCT) imaging is being increasingly used in clinical practice for the monitoring of papilloedema. The aim is to characterise the extent and location of the Retinal Nerve Fibre Layer (RNFL) Thickness automated segmentation error (SegE) by manual refinement, in a cohort of Idiopathic Intracranial Hypertension (IIH) patients with papilloedema and compare this to controls.

    Methods: Baseline Spectral Domain OCT (SDOCT) scans from patients with IIH, and controls with no retinal or optic nerve pathology, were examined. Read More

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