6,344 results match your criteria Papilledema


Unilateral Papilledema as the Presenting Sign of Spinal Metastases.

Ophthalmology 2019 May;126(5):763

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Kensington Vision and Research Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ophtha.2019.02.022DOI Listing

Assessment of the Olfactory Function in Patients With Idiopathic Intracranial Hypertension Using the Sniffin' Sticks Test: A Case-Control Study.

Headache 2019 Apr 18. Epub 2019 Apr 18.

Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Objective: Despite the lack of recognition in clinical practice, there is increasing evidence that patients with idiopathic intracranial hypertension may suffer from hyposmia. The current case-control study aims to evaluate olfactory dysfunction in a large series of patients with idiopathic intracranial hypertension.

Methods: All subjects, 44 idiopathic intracranial hypertension patients and 57 healthy controls, underwent olfactory function assessment using standardized "Sniffin' Sticks" test at a tertiary referral center of a university hospital. Read More

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http://dx.doi.org/10.1111/head.13538DOI Listing

Intracranial Venous Sinus Stenting: A Review of Idiopathic Intracranial Hypertension and Expanding Indications.

Cureus 2019 Feb 4;11(2):e4008. Epub 2019 Feb 4.

Neurosurgery, Penn State Milton Health S. Hershey Medical Center, Hershey, USA.

Idiopathic intracranial hypertension (IIH) is a functionally limiting disorder secondary to increased intracranial pressures (ICPs) with a prevalence of one per 100,000 persons. It is estimated to cost >$400 million per year in productively. Symptoms classically consist of chronic headaches, papilledema, and visual loss. Read More

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http://dx.doi.org/10.7759/cureus.4008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450594PMC
February 2019

Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report.

J Med Case Rep 2019 Apr 19;13(1):94. Epub 2019 Apr 19.

Neurology Department, University of Minnesota, Minneapolis, MN, USA.

Background: Idiopathic intracranial hypertension, also known as pseudotumor cerebri, is a disorder characterized by increased intracranial pressure of unclear pathogenesis in the absence of other structural and obstructive lesions that is predominantly, although not exclusively, seen in obese women of childbearing age. Patients with idiopathic intracranial hypertension commonly present with a headache, transient visual obscurations, and intracranial noises with some cranial nerves occasionally involved, most commonly CN VI. We report idiopathic intracranial hypertension presenting with isolated complete unilateral facial nerve palsy, as the sole cranial nerve involved, which is a presentation rarely reported in the literature. Read More

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http://dx.doi.org/10.1186/s13256-019-2060-5DOI Listing

Spectrum of the neurologic manifestations in childhood-onset cryopyrin-associated periodic syndrome.

Eur J Paediatr Neurol 2019 Mar 28. Epub 2019 Mar 28.

Department of Pediatric Neurology, Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Istanbul, Turkey.

Objective: Neurologic complications of chronic infantile neurologic, cutaneous and articular syndrome (CINCA) are well-known, whereas there are scarce data regarding neurologic features of milder cryopyrin-associated periodic syndrome (CAPS) phenotypes. We aimed to review the neurologic features in detail and summarize the other CAPS-related manifestations in 12 children.

Methods: All children with CAPS that have been followed-up from pediatric rheumatology outpatient clinic, were enrolled to the study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10903798183056
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http://dx.doi.org/10.1016/j.ejpn.2019.03.006DOI Listing
March 2019
2 Reads

Endovascular stenting of the superior sagittal sinus to alleviate venous compression caused by a parasagittal meningioma.

BMJ Case Rep 2019 Apr 5;12(4). Epub 2019 Apr 5.

Department of Neurosurgery, Albany Medical Center, Albany, New York, USA.

Idiopathic intracranial hypertension (IIH) is a challenging disease with unclear pathophysiology. Recognition of venous sinus stenting to improve intracranial pressure is increasing.We present a 56-year-old man diagnosed with IIH. Read More

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http://dx.doi.org/10.1136/bcr-2018-227935DOI Listing

Management of Peripapillary Choroidal Neovascular Membrane in Patients With Idiopathic Intracranial Hypertension.

J Neuroophthalmol 2019 Apr 2. Epub 2019 Apr 2.

Department of Ophthalmology (CO), Gulhane Training and Research Hospital, Ankara, Turkey; Department of Ophthalmology and Visual Sciences (OM, LBD, WTC, CGB), W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan; Department of Ophthalmology (MM), Mid-Atlantic Permanente Medical Group, Rockville, Maryland; Department of Ophthalmology and Visual Neurosciences (MSL), University of Minnesota, Minneapolis, Minnesota; Department of Ophthalmology and Neurology Mayo Clinic (MTB), Rochester, Minnesota; Department of Ophthalmology (KL), University Hospital Zurich and University of Zurich, Zurich, Switzerland; Department of Ophthalmology (GPVS), Washington University in St. Louis, St. Louis, Missouri; Department of Ophthalmology (DDM), Indiana University School of Medicine, Indianapolis, Indiana; Department of Ophthalmology (ML), Hôpital Delafontaine, Saint-Denis, France; and Department of Neurology (LBD, WTC), University of Michigan, Ann Arbor, Michigan.

Objective: To report the clinical features and treatment outcomes of patients with peripapillary choroidal neovascular membrane (CNVM) secondary to idiopathic intracranial hypertension (IIH).

Methods: Retrospective, multicenter chart review of patients diagnosed with peripapillary CNVM in the course of the treatment and follow-up of IIH.

Results: Records were reviewed from 7 different institutions between 2006 and 2016. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000781DOI Listing

Endovascular stenting for idiopathic intracranial hypertension with venous sinus stenosis.

Brain Behav 2019 Apr 4:e01279. Epub 2019 Apr 4.

Department of Neurology, Chinese PLA General Hospital, Beijing, China.

Objectives: Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure of unknown etiology and venous sinus stenting may be an optional treatment. We aimed to evaluate the effects of venous sinus stenting on visual function, intracranial pressure, and trans-stenotic pressure gradient of the patients with IIH and to determine effects of baseline BMI or weight changes on subjective vision outcome and intracranial pressure.

Methods: From July 2009 to Aug 2016, 88 eligible patients with IIH and venous sinus stenosis who underwent stenting were retrospectively studied. Read More

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http://dx.doi.org/10.1002/brb3.1279DOI Listing
April 2019
1 Read

Papilledema from gain-of-function mutations in the STAT3 gene.

Ophthalmic Genet 2019 Apr 3:1-5. Epub 2019 Apr 3.

b Beckman Vision Center, Program in Neuroscience , University of California , San Francisco , CA , USA.

Background: Signal Transducer and Activator of Transcription 3 (STAT3) gain-of-function germline mutations are associated with diverse clinical manifestations, including autoimmune cytopenia, lymphadenopathy, immunodeficiency, endocrinopathy, and enteropathy. We describe a new feature: raised intracranial pressure with papilledema.

Materials And Methods: Report of two cases. Read More

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http://dx.doi.org/10.1080/13816810.2019.1592202DOI Listing
April 2019
1 Read

Eagle Syndrome as a Cause of Cerebral Venous Sinus Thrombosis.

Can J Neurol Sci 2019 Apr 1:1-2. Epub 2019 Apr 1.

Department of Neurology, Stroke Center, Neuroscience Center,The First Hospital of Jilin University,Changchun,China.

A 15-year-old teenager presented with a 2-month history of headache. Neurological examination was normal except for papilledema. Further lumbar puncture indicated intracranial hypertension (330 mm H2O). Read More

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http://dx.doi.org/10.1017/cjn.2019.17DOI Listing
April 2019
3 Reads

An extremely aggressive case of Marburg's disease treated with high dose cyclophosphamide. A case report.

Mult Scler Relat Disord 2019 Mar 23;31:51-53. Epub 2019 Mar 23.

Division of Neurology, University of Puerto Rico School of Medicine, PO Box 365067, San Juan, Puerto Rico, 00936-5067.

Background: The acute, fulminant type of Multiple Sclerosis (MS), known as Marburg Disease, has been shown to have poor response to conventional acute treatments typically used for demyelinating diseases.

Methods: We report a 20 y/o postpartum female who was consulted to the Neurology service given findings of subacute left sided hemiparesis, left homonymous hemianopsia and bilateral papilledema. Extensive workup, including Brain and Cervical spine MRI with and without gadolinium, blood work, CSF studies, in addition to her rapid clinical decline, were highly suggestive of the demyelinating variant of Multiple Sclerosis known as Marburg Disease. Read More

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http://dx.doi.org/10.1016/j.msard.2019.03.014DOI Listing
March 2019
1 Read

Headache in Postoperative Isolated Sagittal Synostosis.

Plast Reconstr Surg 2019 Apr;143(4):798e-805e

Rotterdam, The Netherlands From the Department of Plastic and Reconstructive Surgery and Hand Surgery and Department of Neurosurgery, Dutch Craniofacial Centre, Erasmus University Medical Center.

Background: This study investigates the relationship between headache and the occurrence of signs associated with intracranial hypertension such as ophthalmic signs, restricted skull growth, and a vertex bulge in children who were operated on for sagittal synostosis.

Methods: A total of 94 patients (aged 6 to 18 years) with sagittal synostosis were asked to indicate their headache frequency. Based on their age at referral, the patients had undergone either frontobiparietal remodeling or an extended strip craniotomy. Read More

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http://dx.doi.org/10.1097/PRS.0000000000005481DOI Listing

Association Between Cycline Antibiotic and Development of Pseudotumor Cerebri Syndrome.

J Am Acad Dermatol 2019 Mar 21. Epub 2019 Mar 21.

The Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN. Electronic address:

Background: Cycline antibiotics (CA) are commonly used to treat acne, blepharitis, and dry eye syndrome (DES). Prescribers or patients may hesitate to use CAs, since they may increase the risk of pseudotumor cerebri syndrome (PTCS).

Objective: To assess whether CA use is associated with an increased risk of PTCS or papilledema and whether the risk depends upon dosage or duration of CA intake. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.03.041DOI Listing
March 2019
2 Reads

Papilledema or pseudopapilledema?

Indian J Ophthalmol 2019 Apr;67(4):449

Oncology Service, Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, 14th Floor, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.4103/ijo.IJO_2013_18DOI Listing

Isolated cerebrospinal fluid hypertension in chronic headache: diagnostic innovations and clinical implications.

Authors:
Francesco Bono

Neurol Sci 2019 Mar 21. Epub 2019 Mar 21.

Center for Headache and Intracranial Pressure Disorders, University Hospital "Mater Domini", Catanzaro, Italy.

Isolated cerebrospinal fluid hypertension (ICH) is a condition of increased cerebrospinal fluid (CSF) pressure in the cranial-spinal compartment without an identifiable cause. Isolated headache is the most common symptom of ICH, while missing may be signs such as papilledema or sixth nerve palsy. This fact makes difficult the clinical diagnosis of headache attributable to ICH in headache sufferers. Read More

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http://dx.doi.org/10.1007/s10072-019-03836-0DOI Listing
March 2019
2 Reads

Inpatient and Emergency Room Ophthalmology Consultations at a Tertiary Care Center.

J Ophthalmol 2019 14;2019:7807391. Epub 2019 Feb 14.

University of Illinois at Chicago, Department of Ophthalmology and Visual Sciences, Chicago, IL, USA.

Background: An ophthalmology consultation service is of significant benefit to patients in the hospital and is an instructive component of a residency education program. Ophthalmology consultations in a hospital present unique challenges to those seen in an outpatient clinic, for which the consulting ophthalmologist should be prepared. The purpose of this study was to profile the emergency room and inpatient ophthalmology consultations seen at an academic institution. Read More

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http://dx.doi.org/10.1155/2019/7807391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393906PMC
February 2019

Ophthalmic Manifestations of Acute Leukemia.

Cureus 2019 Jan 7;11(1):e3837. Epub 2019 Jan 7.

Department of Ophthalmology, Jinnah Hospital Lahore (JHL)/Allama Iqbal Medical College (AIMC), Lahore, PAK.

Introduction Ocular involvement in leukemia may occur because of direct leukemic infiltration or because of secondary ophthalmic involvement as a result of abnormalities related to blood like anemia, thrombocytopenia, and leukocytosis. In some patients with leukemia, ophthalmic signs can precede the systemic features and can help in early diagnosis of systemic leukemia. Due to the scarcity of data on this topic from Pakistan, we conducted this study to determine the pattern of ocular involvement in patients with leukemia presenting in our settings. Read More

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http://dx.doi.org/10.7759/cureus.3837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411336PMC
January 2019
2 Reads

Vogt-Koyanagi-Harada syndrome: what neurologists need to know.

Pract Neurol 2019 Mar 19. Epub 2019 Mar 19.

Neurology, The Canberra Hospital, Canberra, Australian Capital Territory, Australia

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http://dx.doi.org/10.1136/practneurol-2018-002165DOI Listing

Tip of the iceberg in idiopathic intracranial hypertension.

Pract Neurol 2019 04;19(2):178-179

Metabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK

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http://dx.doi.org/10.1136/practneurol-2019-002198DOI Listing
April 2019
2 Reads

Novel advances in monitoring and therapeutic approaches in idiopathic intracranial hypertension.

Curr Opin Neurol 2019 Mar 6. Epub 2019 Mar 6.

Birmingham Neuro-Ophthalmology, Queen Elizabeth Hospital.

Purpose Of Review: The current article appraises the recent developments in idiopathic intracranial hypertension (IIH), with particular attention to novel therapeutic avenues and advanced clinical assessment and monitoring with optical coherence tomography and telemetric intracranial pressure devices.

Recent Findings: The incidence of IIH is increasing. The first consensus guidelines for IIH have been published detailing investigation and management algorithms for adult IIH. Read More

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http://dx.doi.org/10.1097/WCO.0000000000000690DOI Listing
March 2019
1 Read

Posterior fossa astroblastoma in a child: a case report and a review of the literature.

Childs Nerv Syst 2019 Mar 12. Epub 2019 Mar 12.

Department of Neurosurgery, Bahçeşehir University School of Medicine, Göztepe Medical Park Training and Education Hospital, Istanbul, Turkey.

A 4-year-old girl presented to the hospital with a progressive headache, difficulty walking, and persistent daily vomiting for 3 weeks. Papilledema was observed on fundoscopic examination. A large left cerebellovermian tumor with "bubbly" appearance was discovered. Read More

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http://dx.doi.org/10.1007/s00381-019-04113-3DOI Listing

[The clinical analysis of optic neuropathy relative to Behcet's disease with clinical manifestation of anterior ischemic optic neuropathy].

Zhonghua Yan Ke Za Zhi 2019 Mar;55(3):203-207

Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

To summarize the clinical manifestation, treatment and prognosis of anterior ischemic optic neuropathy(AION) which was the manifestation of optic neuropathy related with Behcet's disease (BD). Retrospective series of case studies. The clinical data of 6 cases (9 eyes) of AION associated with BD who were hospitalized at the neurology ward of Beijing Tongren Hospital from February to June in 2016 were collected, the clinical characteristics of these patients were summarized, visual acuity were compared by using Wingerchuk visual grade before and after treatment. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.03.009DOI Listing
March 2019
9 Reads

Dural sinus collapsibility, idiopathic intracranial hypertension, and the pathogenesis of chronic migraine.

Neurol Sci 2019 Mar 6. Epub 2019 Mar 6.

Istituto di Diagnosi e Cura Hermitage Capodimonte, Naples, Italy.

Available evidences suggest that a number of known assumption on idiopathic intracranial hypertension (IIH) with or without papilledema might be discussed. These include (1) the primary pathogenetic role of an excessive dural sinus collapsibility in IIH, allowing a new relatively stable intracranial fluids pressure balance at higher values; (2) the non-mandatory role of papilledema for a definite diagnosis; (3) the possibly much higher prevalence of IIH without papilledema than currently considered; (4) the crucial role of the cerebral compliance exhaustion that precede the raise in intracranial pressure and that may already be pathologic in cases showing a moderately elevated opening pressure; (5) the role as "intracranial pressure sensor" played by the trigeminovascular innervation of dural sinuses and cortical bridge veins, which could represent a major source of CGRP and may explain the high comorbidity and the emerging causative link between IIHWOP and chronic migraine (CM). Accordingly, the control of intracranial pressure is to be considered a promising new therapeutic target in CM. Read More

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http://dx.doi.org/10.1007/s10072-019-03775-wDOI Listing
March 2019
4 Reads

Non secretory Paraganglioma in cavernous sinus masquerading as meningioma.

World Neurosurg 2019 Mar 1. Epub 2019 Mar 1.

Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, 226014, India.

Background: Paraganglioma in cavernous sinus is a rare entity often misdiagnosed as meningioma or schwanomma on radiology. The embryological origin, from cells of neural crest, does not explain location per se. Due to highly vascular nature and close proximity to carotid artery, surgical excision is a challenge. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.111DOI Listing
March 2019
2 Reads

Slit Ventricle Syndrome Leads to a 10-year history of Repetitive Transient Central Herniation Masquerading as Seizures: A Hydrocephalus Case Report.

World Neurosurg 2019 Mar 1. Epub 2019 Mar 1.

University of Wisconsin Hospital and Clinics, Neurosurgery Department. Madison, Wisconsin.

Background: Slit-ventricle syndrome (SVS) is a recognized complication of ventricular shunt malfunction, resulting in cyclical symptoms without ventricular dilatation. We present a case of SVS with transient, repetitive, and progressive signs of brainstem herniation evidenced by pupillary dilatation, posturing, and unresponsiveness, with diffuse voltage attenuation on EEG.

Case Description: 32-year-old female with history of hydrocephalus and VP shunt placement at 9 months of age. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.106DOI Listing
March 2019
2 Reads

Utility of Magnetic Resonance Imaging Features for Improving the Diagnosis of Idiopathic Intracranial Hypertension Without Papilledema.

J Neuroophthalmol 2019 Feb 26. Epub 2019 Feb 26.

Department of Neurology (RMM), Brigham and Women's Hospital, Boston, Massachusetts; Department of Ophthalmology (RMM), Massachusetts Eye and Ear Infirmary, Boston, Massachusetts; East Tennessee Medical Group-Neurology (OFR), Blount Memorial Hospital, Maryville, Tennessee; Department of Radiology (JHW, YJC), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Texas Neurology Consultants (SR), Texas Health Resources, Plano, Texas; Department of Radiology (KLS, LL), University of Utah School of Medicine, Salt Lake City, Utah; Department of Radiology (MCP), University of Texas Southwestern Medical Center, Dallas, Texas; Department of Ophthalmology (MAT, KSS, GTL), University of Pennsylvania Scheie Eye Institute, Philadelphia, Pennsylvania; Departments of Ophthalmology and Neurology (KBD), University of Utah School of Medicine, Salt Lake City, Utah; Departments of Neurology and Neurotherapeutics and Ophthalmology (DIF), University of Texas Southwestern Medical Center, Dallas, Texas; Department of Neurology (MAT, KSS, GTL), Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; and Division of Ophthalmology (GTL), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Objective: Revised diagnostic criteria for idiopathic intracranial hypertension (IIH) were proposed in part to reduce misdiagnosis of intracranial hypertension without papilledema (WOP) by using 3 or 4 MRI features of intracranial hypertension when a sixth nerve palsy is absent. This study was undertaken to evaluate the sensitivity and specificity of the MRI criteria and to validate their utility for diagnosing IIH in patients with chronic headaches and elevated opening pressure (CH + EOP), but WOP.

Methods: Brain MRIs from 80 patients with IIH with papilledema (WP), 33 patients with CH + EOP, and 70 control patients with infrequent episodic migraine were assessed in a masked fashion for MRI features of intracranial hypertension. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000767DOI Listing
February 2019
6 Reads

Optic nerve sheath fenestration in patients with visual failure associated with vestibular schwannoma.

Br J Neurosurg 2019 Mar 4:1-7. Epub 2019 Mar 4.

a Department of Ophthalmology , Royal Hallamshire Hospital , Sheffield , UK.

Background: Papilloedema and visual failure can occur as a consequence of vestibular schwannoma without evidence of hydrocephalus on imaging. Conventional treatment usually includes CSF diversion procedures. We describe here the novel use of optic nerve sheath fenestration in these patients. Read More

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http://dx.doi.org/10.1080/02688697.2018.1538482DOI Listing

Surgical intervention in pediatric intracranial hypertension: incidence, risk factors, and visual outcomes.

J AAPOS 2019 Feb 28. Epub 2019 Feb 28.

Department of Ophthalmology, Nationwide Children's Hospital, Columbus, Ohio. Electronic address:

Purpose: To evaluate the incidence of surgical intervention in pediatric intracranial hypertension (IH), evaluate the visual outcomes of surgically managed patients, and identify potential predictors for surgical intervention.

Methods: The medical records of patients with primary and secondary IH at Nationwide Children's Hospital from 2010 to 2017 were reviewed retrospectively. Presenting characteristics of medically and surgically managed patients were compared, and the clinical courses of surgically managed patients were reviewed. Read More

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http://dx.doi.org/10.1016/j.jaapos.2018.11.006DOI Listing
February 2019
1 Read

Bilateral Papilledema and Partially Empty Sella in a Woman in Her 30s.

JAMA Ophthalmol 2019 Feb 28. Epub 2019 Feb 28.

State Key Laboratory of Ophthalmology, Image Reading Center, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China.

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http://dx.doi.org/10.1001/jamaophthalmol.2018.6948DOI Listing
February 2019
1 Read

An Active Duty Sailor With Worsening Headaches and Blurry Vision.

Mil Med 2019 Feb 22. Epub 2019 Feb 22.

Optometry, Branch Health Clinic Naval Station Norfolk, 1721 Admiral Taussig Blvd, Norfolk, VA.

Headaches are a typical presentation to a military medical department or emergency room. Having a broad differential diagnosis and utilizing a thorough physical exam can assist providers in honing down the list of pathology and in identifying potentially life-threatening causes of cephalgia such as intracranial tumors. In this case, a 27-year-old man presented with progressive headaches along with vision changes for the preceding 2-3 months. Read More

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http://dx.doi.org/10.1093/milmed/usy401DOI Listing
February 2019

Detection of Papilloedema Study (DOPS): rates of false positive papilloedema in the community.

Eye (Lond) 2019 Feb 20. Epub 2019 Feb 20.

Bristol Medical School: Population Health Sciences, University of Bristol, Bristol, UK.

Background: Overdiagnosis of papilloedema is common and carries significant potential for morbidity from over-investigation and over-treatment. We aimed to determine the community prevalence of false positive diagnosis of papilloedema (FPE) on fundus imaging.

Methods: We evaluated fundus images from a community cross-section of 198 12-14-year-olds from the Avon Longitudinal Study of Parents and Children (ALSPAC) longitudinal cohort study database and patient images from our hospital departmental database with and without papilloedema. Read More

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http://dx.doi.org/10.1038/s41433-019-0355-9DOI Listing
February 2019

Decreased retinal nerve fiber layer thickness in patients with cerebral venous thrombosis.

BMC Ophthalmol 2019 Feb 20;19(1):57. Epub 2019 Feb 20.

Department of Neurology, Acıbadem Kayseri Hospital, Kayseri, Turkey.

Background: To identify thickness variations in the retinal nerve fiber layer around the optic disc and macula in patients with cerebral vein thrombosis (CVT) without papilledema.

Methods: This study included 28 patients with CVT diagnosis and appropriate treatment. Detailed ophthalmologic examination found bilateral vision 10/10, vision field test normal and fundus examination found no papilledema images. Read More

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http://dx.doi.org/10.1186/s12886-019-1046-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383271PMC
February 2019
2 Reads

Predictive role of presenting symptoms and clinical findings in idiopathic intracranial hypertension.

J Neurol Sci 2019 Apr 6;399:89-93. Epub 2019 Feb 6.

Danish Headache Center, Department of Neurology, University of Copenhagen, Rigshospitalet-Glostrup, Denmark.

Background: The aim of the study was to evaluate the presenting symptoms and signs of idiopathic intracranial hypertension (IIH) in a large cohort of patients and to estimate their possible role in establishing the diagnosis of IIH.

Methods: This prospective cohort study in two tertiary centers, the Danish Headache Center in Rigshospitalet-Glostrup and the Neurology Clinic of the Clinical Center of Serbia, included 286 patients referred by attending specialists for possible IIH evaluation. Patients were divided into two groups: one with confirmed IIH diagnosis and one with rejected IIH diagnosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X193006
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http://dx.doi.org/10.1016/j.jns.2019.02.006DOI Listing
April 2019
4 Reads

[Ocular Phenotype and Complications in Patients with Tuberous Sclerosis Complex (TSC)].

Klin Monbl Augenheilkd 2019 Apr 14;236(4):462-468. Epub 2019 Feb 14.

Augenklinik, UniversitätsSpital Zürich, Schweiz.

Background: Evaluation and comparison of the ocular phenotype in patients diagnosed with tuberous sclerosis complex (TSC). Analysis of ocular complications during follow-up.

Patients And Methods: A retrospective chart review was performed of patients with TSC who had received an ocular examination at the eye clinic of the University Hospital Zurich. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0804-1816
Publisher Site
http://dx.doi.org/10.1055/a-0804-1816DOI Listing
April 2019
9 Reads

Commentary: Idiopathic Intracranial Hypertension Without Papilledema (IIHWOP) in Chronic Refractory Headache.

Front Neurol 2019 29;10:39. Epub 2019 Jan 29.

Division of Neurology and Stroke Unit, Hospital A. Cardarelli, Naples, Italy.

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http://dx.doi.org/10.3389/fneur.2019.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361781PMC
January 2019
1 Read

Spontaneous intracranial hypotension associated with pachymeningeal enhancement in a patient with systemic lupus erythematosus (SLE): an extremely rare presenting feature.

BMJ Case Rep 2019 Feb 7;12(2). Epub 2019 Feb 7.

Medicine, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry, Pondicherry, India.

A 16-years-old girl presented to our institution with history of severe bilateral headache for 5 days associated with vomiting. She also had fever for 2 months without any localising symptoms and skin lesions for 1 month. Examination revealed erythematous rash over bridge of nose and ear lobes, ulcer over hard palate and tenderness of small joints of both hands. Read More

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http://dx.doi.org/10.1136/bcr-2018-227780DOI Listing
February 2019
3 Reads

Long-term outcomes of cerebral venous sinus stenosis corrected by stenting

Curr Neurovasc Res 2019 02 6. Epub 2019 Feb 6.

Departments of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China

Background And Purpose: Cerebral venous sinus stenosis (CVSS) usually results in severe intracranial hypertension (IH), which can be corrected by stenting immediately. However, there is a lack of evidence of the long-term good outcomes in patients with CVSS who underwent stenting.

Methods: A total of 62 patients with imaging confirmed non-thrombotic and non-external compression CVSS were enrolled into this single center real-world cohort study after undergoing stenting, and were continuously followed up for more than 12 years. Read More

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http://dx.doi.org/10.2174/1567202616666190206185133DOI Listing
February 2019
4 Reads

Ganglion Cell Complex Analysis as a Potential Indicator of Early Neuronal Loss in Idiopathic Intracranial Hypertension.

Neuroophthalmology 2019 Feb 19;43(1):10-17. Epub 2018 Jun 19.

The New England Eye Center, Tufts Medical Center, Boston, Massachusetts, USA.

Reliable visual field testing is the gold standard in identifying future vision loss in patients with Idiopathic Intracranial hypertension (IIH). However, when field performance is unreliable, GCC analysis may be useful. We evaluated IIH patients over three visits: initial visit, follow-up visit and a third visit, almost 1 year later. Read More

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http://dx.doi.org/10.1080/01658107.2018.1476558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351016PMC
February 2019
4 Reads

Do Optic Canal Dimensions Measured on CT Influence the Degree of Papilloedema and Visual Dysfunction in Idiopathic Intracranial Hypertension?

Neuroophthalmology 2019 Feb 26;43(1):3-9. Epub 2018 Jun 26.

Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK.

A recent study found that increased optic canal area on magnetic resonance imaging was associated with worse papilloedema in idiopathic intracranial hypertension (IIH). We repeated this study using more accurate computerized tomography derived measurements. Optic canal dimensions were measured from 42 IIH patients and 24 controls. Read More

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http://dx.doi.org/10.1080/01658107.2018.1483406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351014PMC
February 2019
4 Reads

Ophthalmological manifestation in patients of tuberculous meningitis.

QJM 2019 Feb 5. Epub 2019 Feb 5.

Professor, Department of Ophthalmology, King George's Medical University, Lucknow, India.

Background: Vision impairment, blindness in particular is a devastating complication in patients with Tubercular meningitis. However information regarding ophthalmological manifestation and its impact on vision is sparse in the literature. This study evaluated the spectrum of ophthalmological manifestations in tuberculous meningitis, including retinal nerve fiber layer thickness assessment by optic coherence tomography and its correlation with visual and clinical outcome. Read More

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http://dx.doi.org/10.1093/qjmed/hcz037DOI Listing
February 2019
4 Reads

Pattern of Idiopathic Intracranial Hypertension in Indian Population.

Ann Indian Acad Neurol 2019 Jan-Mar;22(1):47-51

Department of Neuromedicine, Medical College, Kolkata, West Bengal, India.

Objective: To evaluate the clinical and demographic profile, laboratory parameters and outcomes of Idiopathic Intracranial hypertension (IIH) patients from Indian subpopulation.

Materials And Method: We did a prospective study on patients who fulfilled the revised diagnostic criteria for Primary pseudotumor cerebri syndrome in adults and children, proposed by Friedman et al in 2013. All patients were examined for BMI, papilloedema, extraocular muscle movement, opening CSF pressure and underwent MRI, MR venography of brain and perimetry. Read More

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http://dx.doi.org/10.4103/aian.AIAN_116_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327693PMC
January 2019
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The comparative analysis of non-thrombotic internal jugular vein stenosis and cerebral venous sinus stenosis.

J Thromb Thrombolysis 2019 Jan 28. Epub 2019 Jan 28.

Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.

Internal jugular vein (IJV) stenosis and cerebral venous sinus (CVS) stenosis belong to cerebral venous outflow insufficiency. This study aimed to analyze the similarities and differences between IJV stenosis and CVS stenosis. Patients with either IJV stenosis or CVS stenosis confirmed by contrast-enhanced magnetic resonance venography between October 2017 and July 2018 were enrolled in this retrospective study. Read More

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http://dx.doi.org/10.1007/s11239-019-01820-1DOI Listing
January 2019
2.039 Impact Factor

Contrast-Enhanced 3D-FLAIR Imaging of the Optic Nerve and Optic Nerve Head: Novel Neuroimaging Findings of Idiopathic Intracranial Hypertension.

AJNR Am J Neuroradiol 2019 Feb 24;40(2):334-339. Epub 2019 Jan 24.

From the Departments of Radiology (E.G., J.-P.J.Y., T.A.K.)

Background And Purpose: The sensitivity of contrast-enhanced 3D-FLAIR has not been assessed in patients with idiopathic intracranial hypertension. The purpose of this study was to evaluate whether hyperintensity of the optic nerve/optic nerve head on contrast-enhanced 3D-FLAIR imaging is associated with papilledema in patients with idiopathic intracranial hypertension.

Materials And Methods: A retrospective review was conducted from 2012 to 2015 of patients with clinically diagnosed idiopathic intracranial hypertension and age- and sex-matched controls who had MR imaging with contrast-enhanced 3D-FLAIR. Read More

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http://dx.doi.org/10.3174/ajnr.A5937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375763PMC
February 2019

"Headache in operated isolated sagittal synostosis."

Plast Reconstr Surg 2019 Jan 21. Epub 2019 Jan 21.

Background: This study investigates the relationship between headache and the occurrence of signs associated with intracranial hypertension (ICH) such as ophthalmic signs, restricted skull growth and a vertex bulge in children who were operated for sagittal synostosis.

Methods: A total of 94 patients (aged 6-18 years) with sagittal synostosis were asked to indicate the headache frequency. Based on their age at referral, the patients had undergone either a fronto-biparietal remodeling (FBR) or an extended strip craniotomy (ESC). Read More

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http://dx.doi.org/10.1097/PRS.0000000000005481DOI Listing
January 2019
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Diagnosis and Management of Cerebral Venous Diseases in Neuro-Ophthalmology: Ongoing Controversies.

Asia Pac J Ophthalmol (Phila) 2019 Jan-Feb;8(1):73-85. Epub 2019 Jan 23.

Department of Ophthalmology, Weill Cornell Medical College, New York, United States.

Diseases of the cerebral venous system frequently lead to neuro-ophthalmic complications. Cortical venous sinus thrombosis and dural arteriovenous fistulas may be complicated by elevation of intracranial pressure, with secondary papilledema or abducens palsies. There is increasing recognition that stenosis at the transverse sinus-sigmoid sinus junction plays a role in the pathophysiology of idiopathic intracranial hypertension and offers a new avenue of treatment in patients who fail medical therapy. Read More

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http://dx.doi.org/10.22608/APO.2018239DOI Listing
March 2019
6 Reads