Search our Database of Scientific Publications and Authors

I’m looking for a

    5937 results match your criteria Papilledema

    1 OF 119

    Recurrence of acute lymphoblastic leukemia manifesting as serous retinal detachments and optic disc swelling.
    Int Ophthalmol 2017 Jul 15. Epub 2017 Jul 15.
    Department of Ophthalmology, Faculty of Medicine, Göztepe Medical Park Hospital, Bahcesehir University, E-5 uzeri 23 Nisan sok No: 17 Merdivenkoy, Kadikoy, Istanbul, Turkey.
    Purpose: The aim of this case report is to describe a patient with acute lymphoblastic leukemia (ALL) who developed bilateral serous retinal detachments and unilateral optic disc swelling.

    Methods: A 23-year-old woman with ALL presented to the ophthalmology clinic with bilateral subacute visual loss.

    Results: Ophthalmologic examination revealed bilateral serous retinal detachments and unilateral optic disc swelling. Read More

    POEMS syndrome: 2017 Update on diagnosis, risk stratification, and management.
    Am J Hematol 2017 Aug;92(8):814-829
    Mayo Clinic, Professor of Medicine and Laboratory Medicine, Rochester, Minnesota, 55905.
    Disease Overview: POEMS syndrome is a paraneoplastic syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyradiculoneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease. Minor features include organomegaly, endocrinopathy, characteristic skin changes, papilledema, extravascular volume overload, and thrombocytosis. Read More

    Predictors of visual outcome in patients operated for craniopharyngioma - a Danish national study.
    Acta Ophthalmol 2017 Jun 29. Epub 2017 Jun 29.
    Department of Ophthalmology, Rigshospitalet, Copenhagen, Denmark.
    Purpose: Craniopharyngioma often causes visual loss due to the close relation to the anterior visual pathways. This study investigates the incidence and predictors of visual outcomes in patients with craniopharyngioma.

    Methods: Data from sixty-six patients who underwent surgery for craniopharyngioma from 2009 to 2013 in Denmark were reviewed. Read More

    [Anterior skull-base schwannoma].
    Neurocirugia (Astur) 2017 Jun 24. Epub 2017 Jun 24.
    Departamento de Anatomía Patológica, Hospital México, Costa Rica; Programa de Investigación Neurocirugía y Órganos de los Sentidos (PINECOS), Universidad de Costa Rica, San José, Costa Rica.
    Schwannomas are nerve sheath tumours that originate in Schwann cells. They are usually solitary and sporadic and manifest on peripheral, spinal or cranial nerves. Intracranial schwannomas tend to manifest on the eighth cranial nerve, particularly in patients with neurofibromatosis type2. Read More

    Detecting optic nerve head swelling on ultrasound and optical coherence tomography in children and young people: an observational study.
    Br J Ophthalmol 2017 Jun 21. Epub 2017 Jun 21.
    NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.
    Background: Following high-profile cases, referrals for evaluation of 'suspicious optic discs' to eye clinics in the UK have sharply increased, asking ophthalmologists to reliably distinguish between true and pseudopapilloedema. Optic nerve sheath dilatation (ONSD) on ocular ultrasound (US) is considered a reliable sign of true papilloedema, but this test is not widely available. Recently, anterior bowing of Bruch's membrane (BM) and increased retinal nerve fibre layer thickness on optical coherence tomography (OCT) have emerged as indicators of intracranial hypertension, and OCT is widely available. Read More

    Uncommon Presentation of Idiopathic Intracranial Hypertension in a Patient with Polycystic Ovary Syndrome: A Case Report.
    Case Rep Neurol 2017 Jan-Apr;9(1):49-53. Epub 2017 Mar 21.
    bKing Abdulaziz Medical City/King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
    Introduction: Idiopathic intracranial hypertension is a rare condition characterized by increased intracranial pressure without clinical, laboratory, or radiological evidence of intracranial pathology. Early management could prevent irreversible outcomes.

    Case Presentation: A 17-year-old single Arabian female of Arab origin presented with a 2-day complaint of horizontal diplopia and transient visual obscurations. Read More

    Optical coherence tomography for the diagnosis and monitoring of idiopathic intracranial hypertension.
    J Neurol 2017 Jul 5;264(7):1370-1380. Epub 2017 Jun 5.
    Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (RMN(2)), Department of Neurology, Johannes Gutenberg University Medical Center, Mainz, Germany.
    The objectives of the study were to investigate the value of optical coherence tomography in detecting papilledema in patients with idiopathic intracranial hypertension (IIH), a disease which is difficult to monitor and which can lead to permanent visual deficits; to analyze retinal changes over time. In this non-interventional case-control study, spectral-domain optical coherence tomography (SD-OCT) was used to analyze the retinal and optic nerve head (ONH) morphology of 21 patients with IIH and 27 age- and sex-matched healthy controls over time. We analyzed the ONH volume using a custom-made algorithm and employed semi-automated segmentation of macular volume scans to assess the macular retinal nerve fiber layer (RNFL) and ganglion cell layer and inner plexiform layer complex as well as the total macular volume. Read More

    Bariatric surgery as a treatment for pseudotumor cerebri: case study and narrative review of the literature.
    Sao Paulo Med J 2017 May 29. Epub 2017 May 29.
    MD, MSc, PhD. Full Professor. Department of Surgery, Faculdade de Ciências Médicas da Universidade Estadual de Campinas (FCM-UNICAMP), Campinas (SP), Brazil.
    Context:: Pseudotumor cerebri occurs when there is an increase in intracranial pressure without an underlying cause, usually leading to loss of vision. It is most commonly observed in obese women of child-bearing age.

    Case Report:: A 46-year-old woman presented at our service with idiopathic intracranial hypertension that had been diagnosed two years earlier, which had led to chronic refractory headache and an estimated 30% loss of visual acuity, associated with bilateral papilledema. Read More

    Radiologically occult medulloblastoma with hydrocephalus: case report.
    Childs Nerv Syst 2017 May 29. Epub 2017 May 29.
    Division of Neurosurgery, National Center for Child Health and Development, Okura 2-10-1, Setagaya-ku, Tokyo, 157-8535, Japan.
    Introduction: There have been no reports of occult medulloblastoma nor noncommunicating hydrocephalus due to radiologically occult brain tumors. Herein, we report radiologically occult medulloblastoma with noncommunicating hydrocephalus.

    Case Report: A 3-year-old boy presented with macrocephaly, visual field constriction, and papilledema. Read More

    Quantitative Association Between Peripapillary Bruch's Membrane Shape and Intracranial Pressure.
    Invest Ophthalmol Vis Sci 2017 May;58(5):2739-2745
    Department of Ophthalmology, Stanford University, Palo Alto, California, United States.
    Purpose: The purpose of this study was to determine if there is a quantitative relationship between chronic intracranial pressure (ICP) and peripapillary Bruch's membrane (pp-BM) shape and to determine whether change in pp-BM shape can be detected within 1 hour after ICP lowering by lumbar puncture (LP).

    Methods: In this study, 30° nasal-temporal optical coherence tomography B-scans were obtained within 1 hour before and after LP in 39 eyes from 20 patients (age = 23-86 years, 75% female, ICP [opening pressure] = 10-55 cm H2O). A total of 16 semi-landmarks defined pp-BM on each image. Read More

    An uncommon case of symptomatic multiple meningiomas with bilateral compressive optic neuropathy rapidly induced under cyproterone acetate treatment.
    Curr Drug Saf 2017 05 23. Epub 2017 May 23.
    Department of Ophthalmology, Hôpital François Quesnay, 2 boulevard Sully, 78201 Mantes-la-Jolie CEDEX, France
    Multiple meningiomas growth in patients under cyproterone acetate (CPA) is now well known. However, time between initial CPA intake and diagnosis remains unclear. The exposure time differs in each reported case: from 2 to 10 years. Read More

    Is Pseudotumor Cerebri An Unusual Expression of Chiari Syndrome? A Case Report and Review of the Literature.
    Surg Technol Int 2017 May 24;30. Epub 2017 May 24.
    Division of Neurosurgery, Department of Neuroscience University of Torino, Torino, Italy.
    The Chiari I malformation (CM-I) is a developmental alteration of the posterior cranial fossa (PCF), radiographically defined as the descent of the cerebellar tonsils = 5 mm below the foramen magnum (FM) inside the cervical canal. Headache is the most frequent symptom associated with CM-I. The association of CM-I and neurological symptoms configures with Chiari syndrome. Read More

    Outcomes of ventriculoperitoneal shunt insertion in the management of idiopathic intracranial hypertension in children.
    Childs Nerv Syst 2017 May 23. Epub 2017 May 23.
    Department of Paediatric Neurosurgery, University Hospital of Wales, Cardiff, UK.
    Purpose: The ventriculoperitoneal (VP) shunt has become the procedure of choice for treatment of idiopathic intracranial hypertension (IIH). We aimed to assess the efficacy of frameless stereotactic placement of VP shunts for the management of medically resistant IIH in children and to assess the role of gender and obesity in the aetiology of the condition.

    Methods: This is a retrospective analysis of the case notes of 10 patients treated surgically at the University Hospital of Wales in Cardiff, from May 2006 to September 2012. Read More

    The efficacy of orbital ultrasonography and magnetic resonance imaging findings with direct measurement of intracranial pressure in distinguishing papilledema from pseudopapilledema.
    Childs Nerv Syst 2017 May 22. Epub 2017 May 22.
    Faculty of Medicine, Department of Ophthalmology, Gazi University, Ankara, Turkey.
    Introduction: The goal of this study was to evaluate the utility of orbital ultrasonography and magnetic resonance imaging in the diagnosis of idiopathic intracranial hypertension (IIH).

    Method: We reviewed the medical records of patients referred to our department for suspected IIH.

    Results: Seven children were diagnosed with IIH. Read More

    [Bilateral papilledema secondary to intracranial hypertension in an adolescent girl].
    Pan Afr Med J 2017 3;26:123. Epub 2017 Mar 3.
    Centre Hospitalier Universitaire, Institut d'Ophtalmologie Tropicale d'Afrique, Boulevard du Peuple, Bamako, Mali, Boulevard du Peuple, Bamako, Mali.
    Papilledema is a fluid and/or axonal swelling of the optic nerve head due to a blockage of axoplasmic flow at the level of the cribriform plate. We report the case of a 17-year old adolescent girl with bilateral papilledema secondary to idiopathic intracranial hypertension. Read More

    A Bloody Mess!
    Surv Ophthalmol 2017 May 17. Epub 2017 May 17.
    Departments of Ophthalmology and Neurology, Emory University, Atlanta, Georgia.
    A 15-year-old girl presented with a unilateral sixth nerve palsy and papilledema following a severe headache. MR imaging showed thrombosis of the superior sagittal sinus and proximal right transverse sinus that were attributed to oral contraceptive use after a coagulation workup was negative. Systemic anticoagulation caused a hemorrhagic papillopathy in both eyes, raising the question as to whether anticoagulation should be discontinued. Read More

    Endolymphatic hydrops in idiopathic intracranial hypertension: prevalence and clinical outcome after lumbar puncture. Preliminary data.
    Neurol Sci 2017 May;38(Suppl 1):193-196
    Department of Neurosciences, Reproductive Sciences and Odontostomatology, Headache Centre, University of Naples "Federico II", Via Pansini, 5, 80131, Naples, Italy.
    Idiopathic intracranial hypertension is characterized by raised intracranial pressure (ICP) without any underlying pathology, presenting with (IIH) or without papilledema (IIHWOP). Headache, often on daily basis, is the most frequent symptom. Among audiovestibular symptoms, tinnitus and dizziness are commonly reported, while vertigo and hearing impairment are infrequent reports. Read More

    Efficacy and safety of optic nerve sheath fenestration in patients with raised intracranial pressure.
    Pak J Med Sci 2017 Mar-Apr;33(2):471-475
    Dr. Qamar Ul Islam, MCPS, FCPS(Ophth), FCPS (Vitreoretina). PNS Shifa Naval Hospital, Karachi, Pakistan.
    Objective: To evaluate the efficacy and safety of Optic Nerve Sheath Fenestration (ONSF) in patients with raised intracranial pressure (ICP).

    Methods: This Quasi Experimental Study was conducted at Armed Forces Institute of Ophthalmology, Rawalpindi from July 2013 to July 2015. Thirty one eyes of 18 patients who underwent ONSF for raised ICP were followed up for one year to ascertain efficacy and safety of ONSF procedure. Read More

    Case of Primary Leptomeningeal Lymphoma Presenting with Papilloedema and Characteristics of Pseudotumor Syndrome.
    Neuroophthalmology 2017 Jun 23;41(3):149-153. Epub 2017 Mar 23.
    Department of Ophthalmology, Osaka Medical College, Osaka, Japan.
    The authors describe an immunocompetent, 50-year-old man who complained of a daily transient blurring of his vision with bilateral papilloedema. His visual acuity was 20/20 OU, and the blind spot was enlarged bilaterally. There was intracranial hypertension, but imaging for systemic and brain tumours were negative. Read More

    Venous hypertensive encephalopathy secondary to venous sinus thrombosis and dural arteriovenous fistula.
    Pract Neurol 2017 Aug 16;17(4):312-313. Epub 2017 May 16.
    Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
    A 52-year-old man with a history of factor V Leiden thrombophilia, persistent headaches and papilloedema presented with worsening vision and confusion. MRI and MR angiography of the brain at the time of this presentation showed findings concerning for transverse sinus thrombosis and an associated dural arteriovenous fistula. Dural venous sinus thrombosis can lead to the formation of a dural arteriovenous fistula, which must be considered in the differential diagnosis for intracranial hypertension in patients with thrombophilia. Read More

    Peripapillary Retinal Pigment Epithelium Layer Shape Changes From Acetazolamide Treatment in the Idiopathic Intracranial Hypertension Treatment Trial.
    Invest Ophthalmol Vis Sci 2017 May;58(5):2554-2565
    Department of Electrical and Computer Engineering, The University of Iowa, Iowa City, Iowa, United States 2Iowa City VA Health Care System and Iowa City VA Center for the Prevention and Treatment of Visual Loss, Iowa City, Iowa, United States.
    Purpose: Recent studies indicate that the amount of deformation of the peripapillary retinal pigment epithelium and Bruch's membrane (pRPE/BM) toward or away from the vitreous may reflect acute changes in cerebrospinal fluid pressure. The study purpose is to determine if changes in optic-nerve-head (ONH) shape reflect a treatment effect (acetazolamide/placebo + weight management) using the optical coherence tomography (OCT) substudy of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) at baseline, 3, and 6 months.

    Methods: The pRPE/BM shape deformation was quantified and compared with ONH volume, peripapillary retinal nerve fiber layer (pRNFL), and total retinal (pTR) thicknesses in the acetazolamide group (39 subjects) and placebo group (31 subjects) at baseline, 3, and 6 months. Read More

    Venous sinus stenting shortens the duration of medical therapy for increased intracranial pressure secondary to venous sinus stenosis.
    J Neurointerv Surg 2017 May 9. Epub 2017 May 9.
    Department of Ophthalmology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
    Introduction: Medical treatment, cerebrospinal fluid (CSF) shunting, and optic nerve sheath fenestration are standard treatments for increased intracranial pressure (ICP) in patients with idiopathic intracranial hypertension (IIH). Venous sinus stenting provides a novel alternative surgical treatment in cases of venous sinus stenosis with elevated ICP.

    Methods: 12 consecutive subjects with papilledema, increased ICP, and radiological signs of dural sinus stenosis underwent cerebral venography and manometry. Read More

    Klin Monbl Augenheilkd 2017 Jun 9;234(6):829-850. Epub 2017 May 9.
    Correct differential diagnosis in cases of blurred optic disc margins is a challenging task for ophthalmologists. The reliable differentiation of pseudopapilloedema and true papilloedema has significant implications for proper patient management. Conditions that give rise to pseudopapilloedema include small crowded discs, tilted discs and optic nerve head drusen. Read More

    Vertex epidural hematoma: An analysis of a large series.
    Asian J Neurosurg 2017 Apr-Jun;12(2):167-171
    Department of Neurosurgery, Madras Institute of Neurology, Madras Medical College and Government General Hospital, Chennai, Tamil Nadu, India.
    Context: Vertex epidural hematoma (VEDH) is uncommon. A high index of suspicion is required to suspect and diagnose this condition, and the surgical management is a challenge to neurosurgeons. There are only isolated case reports or small series of VEDH in the literature. Read More

    [Bilateral papilledema].
    J Fr Ophtalmol 2017 May 6;40(5):422-429. Epub 2017 May 6.
    Service d'ophtalmologie, CHU de Bordeaux, place Amelie-Raba-Léon, 33000 Bordeaux, France; Inserm, U1219, Bordeaux Population Health Research Center, 33000 Bordeaux, France. Electronic address:
    This article will review the current standard of care in the diagnosis and management of bilateral optic disc edema. Two emergent conditions must be considered first: secondary intracranial hypertension (cerebral tumor, cerebral thrombophlebitis…) and arteritic ischemic optic neuropathy (or giant cell arteritis). Having ruled out these two diagnoses, the management follows various steps in order to: (i) rule out pseudo-edema, and (ii) determine the underlying cause of the edema: papilledema, non-arteritic ischemic optic neuropathy or papillitis. Read More

    Optic Nerve Sheath Diameter as a Bedside Assessment for Elevated Intracranial Pressure.
    Case Rep Crit Care 2017 5;2017:3978934. Epub 2017 Apr 5.
    Western Health, Gordon Street, Footscray, VIC 3011, Australia.
    A previously fit and healthy 26-year-old lady with no significant medical history presented with a two-month history of headaches. The headaches were prolonged, generalised, and unusually severe for the patient. Examination revealed papilloedema. Read More

    Clinical Profile, Outcome, and Prognostic Factors of Cortical Venous Thrombosis in a Tertiary Care Hospital, India.
    J Neurosci Rural Pract 2017 Apr-Jun;8(2):204-208
    Department of Community Medicine, SDM Medical College and Hospital, Sattur, Dharwad, Karnataka, India.
    Background: Cortical venous thrombosis (CVT) is a rare condition, compared to arterial stroke and often occurs in young individuals presenting with varying clinical features.

    Aim: The aim is to study clinical profile and assess the outcome and prognostic factors of CVT patients.

    Methodology: A case series study was done for 2 years. Read More

    Sildenafil-related cerebral venous sinus thrombosis and papilledema: a case report of a rare entity.
    Neurol Sci 2017 May 4. Epub 2017 May 4.
    Department of Neurology, Ege University Medical Faculty, Izmir, Turkey.
    We present a rare case of cerebral venous sinus thrombosis associated with long-term and high-dose use of sildenafil. A 29-year-old man was referred to our neuroophthalmology clinic for bilateral visual deterioration and severe headache. He had stage 2 papilledema and other clinical and neurological examinations were normal. Read More

    Intravitreal Ranibizumab Injection in Peripapillary CNVM Related to Idiopathic Intracranial Hypertension.
    J Pediatr Ophthalmol Strabismus 2017 Apr 28;54:e27-e30. Epub 2017 Apr 28.
    Peripapillary choroidal neovascular membrane (CNVM) may develop in papilledema related to idiopathic intracranial hypertension. The authors present a teenaged boy who responded well to one dose of intravitreal ranibizumab injection. [J Pediatr Ophthalmol Strabismus. Read More

    Objective Measures of Visual Function in Papilledema.
    Adv Ophthalmol Optom 2016 Aug;1(1):231-247
    Department of Ophthalmology & Visual Sciences, Department of Neurology & Rehabilitation, University of Illinois at Chicago, Chicago, IL.
    Visual function is an important parameter to consider when managing patients with papilledema. Though the current standard of care uses standard automated perimetry (SAP) to obtain this information, this test is inherently subjective and prone to patient errors. Objective visual function tests including the visual evoked potential, pattern electroretinogram, photopic negative response of the full field electroretinogram, and pupillary light response have the potential to replace or supplement subjective visual function tests in papilledema management. Read More

    Experimental Anterior Ischemic Optic Neuropathy in Diabetic Mice Exhibited Severe Retinal Swelling Associated With VEGF Elevation.
    Invest Ophthalmol Vis Sci 2017 Apr;58(4):2296-2305
    Department of Ophthalmology, Stanford University School of Medicine, Stanford, California, United States.
    Purpose: Diabetes mellitus (DM) is one of the most important risk factors for nonarteritic anterior ischemic optic neuropathy (AION). In this study, we investigated for the first time the impact of experimental AION in a DM model.

    Methods: We induced a photochemical thrombosis model of AION after streptozotocin-induced DM and performed serial optical coherence tomography (OCT), morphometric analyses, and VEGF levels in the retina and sera. Read More

    Primary intracranial choriocarcinoma presenting as a ring-enhancing lesion: A case report and review of literature.
    Asian J Neurosurg 2017 Jan-Mar;12(1):85-88
    Department of Neurosurgery, Grant Medical College and Sir J. J. Group of Hospitals, Byculla, Mumbai, Maharashtra, India.
    We report here a rare case of primary intracranial choriocarcinoma without evidence of tumor elsewhere, presenting as a ring-enhancing lesion managed successfully in our institute (Grant Medical College and Sir J. J. Group of Hospitals, Mumbai, Maharashtra, India). Read More

    Relationship between lamina cribrosa displacement and trans-laminar pressure difference in papilledema.
    Graefes Arch Clin Exp Ophthalmol 2017 Jun 8;255(6):1237-1243. Epub 2017 Apr 8.
    Department of Ophthalmology, Hospital Universitario Ramón y Cajal, Carretera de Colmenar Viejo, km. 9.100, 28034, Madrid, Spain.
    Purpose: The purpose of this study was to describe morphological changes in lamina cribrosa (LC), prelaminar tissue thickness (PTT) and Bruch's membrane opening (BMO) in eyes affected by papilledema and correlate them with trans-LC-pressure difference (TLCD).

    Methods: This was a prospective study, including twelve eyes newly diagnosed of papilledema. Eyes underwent scanning with Spectralis-OCT with enhanced depth imaging to compare BMO, anterior LC surface position (LC depth-LCD-) and PTT before and after oedema resolution. Read More

    Intestinal and neurological involvement in Behcet disease: a clinical case.
    Ital J Pediatr 2017 Apr 7;43(1):33. Epub 2017 Apr 7.
    Department of Human Pathology in Adulthood and Childhood "G. Barresi", Unit of Pediatrics, University of Messina, Messina, Italy.
    Background: Behcet's disease (BD) is a chronic immune-mediated, inflammatory disorder which may affect a number of different systems (oral and genital mucosa, eyes, skin, vascular district, joints, gastrointestinal tract and nervous system). Neurological manifestations are present in 5-10%, and gastrointestinal tract involvement in 10-15% of cases. The simultaneous involvement of two systems, neurological and gastrointestinal tract, is very rare and represents the aim of our case report. Read More

    Papilledema in children with hydrocephalus: incidence and associated factors.
    J Neurosurg Pediatr 2017 Jun 7;19(6):627-631. Epub 2017 Apr 7.
    Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.
    OBJECTIVE The aim of this study was to report the incidence of and the factors associated with papilledema in children with hydrocephalus. METHODS Patients younger than 15 years of age who had been diagnosed with hydrocephalus and treated by extra-ventricular drainage or ventriculoperitoneal shunt surgery between 2005 and 2015 were retrospectively reviewed. Factors including patient age and sex, etiology of hydrocephalus, duration of signs or symptoms, intracranial pressure (ICP), and presence of papilledema were evaluated. Read More

    Outcomes of endoscopic optic nerve decompression in patients with idiopathic intracranial hypertension.
    Int Forum Allergy Rhinol 2017 Jun 6;7(6):615-623. Epub 2017 Apr 6.
    Department of Otolaryngology Head & Neck Surgery, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico.
    Background: The conventional treatment for idiopathic intracranial hypertension involves weight loss, steroids, diuretics, and/or serial lumbar punctures; however, if the symptoms persist or worsen, surgical intervention is recommended. Surgical options include cerebrospinal fluid diversion procedures, such as ventriculoperitoneal and lumboperitoneal shunts, and optic nerve decompression with nerve sheath fenestration. The latter can be carried out using an endoscopic approach, but the outcomes of this technique have not been firmly established. Read More

    Lesson of the month 2: A choroid plexus papilloma manifesting as anorexia nervosa in an adult.
    Clin Med (Lond) 2017 Apr;17(2):183-185
    Basildon University Hospital, Basildon, UK.
    A Caucasian female previously diagnosed with anorexia nervosa was referred by psychiatric services to the general medical team. She presented with dehydration, vomiting, weakness, a body mass index of 13 kg/m(2) and was treated with intravenous and enteral supplementation. During admission her vomiting worsened and she developed visual hallucinations and confabulation. Read More

    Intracanalicular Optic Nerve Swelling and Signal Change in Fulminant Untreated Idiopathic Intracranial Hypertension.
    Neuroophthalmology 2017 Apr 20;41(2):84-89. Epub 2016 Dec 20.
    Department of Neurology, University of KwaZulu-Natal, Durban, South Africa; Department of Radiology, Greys Hospital, Pietermaritzburg, South Africa.
    The role of the optic canal in the pathogenesis of papilloedema has been under scrutiny recently. Whether a larger canal precedes more severe papilloedema or is the result of bone remodelling from chronically raised pressure across a pressure gradient is not clear. The authors present the magnetic resonance imaging findings of a 29-year-old female with fulminant and untreated idiopathic intracranial hypertension. Read More

    Update on the application of optic nerve sheath fenestration.
    Restor Neurol Neurosci 2017 ;35(3):275-286
    Sichuan Provincial Key Laboratory for Disease Gene Study, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China.
    Background: With the ongoing development of surgical procedures and instruments, the safety of optic nerve sheath fenestration (ONSF) has been improved.

    Objective: Through the past three decades, progress has been made in preventing visual loss from chronic optic nerve swelling in idiopathic intracranial hypertension (IIH), secondary intracranial hypertension and local optic nerve diseases. We now review the updated application of ONSF in those diseases. Read More

    Idiopathic intracranial hypertension in a paediatric population: a retrospective observational study on epidemiology, symptoms and treatment.
    J Biol Regul Homeost Agents 2017 Jan-Mar;31(1):195-200
    General Paediatrics O.U., Policlinico-Vittorio Emanuele University Hospital, University of Catania, Italy.
    Idiopathic intracranial hypertension (IIH) is a disorder of unknown origin, which is characterized by elevated intracranial pressure (ICP) without underlying etiological evidence of neurological disease. The purpose of the current study was to evaluate epidemiological features, clinical presentation, diagnostic findings and treatment of sixteen children (7 males and 9 females) with IIH. Medical records of the patients were obtained from the University Paediatric Hospital of Catania, Italy. Read More

    Orbital Hydatid Cyst Causing Papilledema and Proptosis in an Adult.
    World Neurosurg 2017 May 16;101:811.e1-811.e4. Epub 2017 Mar 16.
    Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran.
    Hydatid cyst is an infectious disease caused by Echinococcus granulosus, primarily involving the liver and lungs. The orbit is an extremely rare site for involvement with hydatid cyst. We present a 36-year-old man with unilateral visual loss, proptosis, and papilledema caused by an orbital hydatid cyst. Read More

    Ocular fundus photography with a smartphone device in acute hypertension.
    J Hypertens 2017 Aug;35(8):1660-1665
    aDepartment of Medicine bDepartment of Ophtalmology, University of Brescia cEmergency Department Gardone Val Trompia, Spedali Civili of Brescia, Brescia, Italy *M. Lorenza Muiesan and Massimo Salvetti have contributed equally to the article.
    Background: The ocular fundus examination is infrequently and poorly performed in the emergency department (ED) clinical settings, placing patients at risk for missed diagnosis of hypertensive emergencies. The aim of this study was to investigate the feasibility of the ocular fundus photography with a smartphone small optical device in an ED setting and to compare it with a traditional ocular fundus examination.

    Methods: The study included 52 consecutive patients (mean age 69 ± 16 years, 50% women) presenting to a hospital ED with an acute increase in blood pressure (SBP > 180 and/or DBP > 100 mmHg). Read More

    Idiopathic Intracranial Hypertension in Monozygotic Female Twins: Intracranial Pressure Dynamics and Treatment Outcome.
    World Neurosurg 2017 May 12;101:814.e11-814.e14. Epub 2017 Mar 12.
    Department of Neurosurgery, Hannover Medical School, Hannover, Germany.
    Background: Familial cases of idiopathic intracranial hypertension (IIH) are exceedingly rare, and its occurrence in monozygotic twins has not been reported previously.

    Case Description: We report monozygotic female twins who developed IIH, one at age 25 years and the other at age 28 years. Continuous intracranial pressure (ICP) monitoring confirmed elevated ICP as measured initially by lumbar puncture. Read More

    POEMS Syndrome: an Enigma.
    Curr Hematol Malig Rep 2017 Apr;12(2):85-95
    Division of Hematology, Medicine and Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
    POEMS syndrome is a paraneoplastic disorder secondary to an underlying plasma cell dyscrasia. By definition, all patients with POEMS syndrome must display polyneuropathy and monoclonal plasma cell disorder. In addition, at least one major criterion (Castleman's disease, sclerotic bone lesions, or vascular endothelial growth factor elevation) and one minor criterion (organomegaly, extravascular volume overload, endocrinopathy, skin changes, papilledema, thrombocytosis, or polycythemia) are required for diagnosis. Read More

    1 OF 119