6,259 results match your criteria Papilledema


Mesalazine treatment causing resolution of intracranial hypertension secondary to ulcerative colitis: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13365

Department of Ophthalmology, Fondation Ophtalmologique Adolphe de Rothschild.

Rationale: The association between intracranial hypertension (ICH) and ulcerative colitis (UC) is rare. We report the unusual case of a male patient with UC and ICH in whom both conditions resolved with mesalazine therapy.

Patient Concerns: A 48-year-old Caucasian man presented to our department in June 2016 for decreased vision, transient visual obscuration, pulsatile tinnitus and headaches of 7 months duration. Read More

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December 2018

Optic Nerve Head Drusen: An Update.

Neuroophthalmology 2018 Dec 25;42(6):367-384. Epub 2018 Apr 25.

Surgery & Anaesthesia, University of Otago Wellington, Wellington, New Zealand.

Optic nerve head drusen are benign acellular calcium concretions that usually form early in life, just anterior to the lamina cribrosa. Improving imaging using optical coherence tomography suggests they are common and may be present in many clinically normal discs. These drusen may change in appearance in early life, but are generally stable in adulthood, and may be associated with visual field defects, anterior ischaemic optic neuropathy, or rarer complications. Read More

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December 2018

Re: Radke et al - The Translaminar Pressure Gradient - Papilledema After Trabeculectomy Treated With Optic Nerve Sheath Fenestration.

Authors:
David Fleischman

J Glaucoma 2018 Dec 11. Epub 2018 Dec 11.

Department of Ophthalmology, University of North Carolina at Chapel Hill.

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December 2018

Cerebral Venous Thrombosis: An Uncommon Cause of Papilledema on Bedside Ocular Ultrasound.

J Emerg Med 2018 Dec 8. Epub 2018 Dec 8.

Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, Florida.

Background: Cerebral venous thrombosis (CVT) is a rare, difficult-to-diagnose form of venous thromboembolic disease and is considered a type of stroke. Its presentation is highly variable and may be easily confused for more common and less debilitating or life-threatening diagnoses such as migraine, seizure, or idiopathic intracranial hypertension.

Case Report: A 25-year-old woman presented with a complaint of bifrontal throbbing headache and blurry vision. Read More

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December 2018

Masking of Papilledema by Glaucoma.

Ann Indian Acad Neurol 2018 Oct-Dec;21(4):330-331

Department of Cornea and IOL, AG Eye Hospital, Trichy, Tamil Nadu, India.

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December 2018

Optic nerve appearance as a predictor of visual outcome in patients with idiopathic intracranial hypertension.

Br J Ophthalmol 2018 Dec 8. Epub 2018 Dec 8.

Department of Ophthalmology, Emory University, Atlanta, Georgia, USA

Background/aims: It remains unclear whether the presence of optic disc haemorrhages (ODH) or cotton wool spots (CWS) at presentation in patients with papilloedema from idiopathic intracranial hypertension (IIH) has prognostic value. The aim of this study was to determine if optic disc appearance at presentation predicts visual outcome in patients with IIH.

Methods: Retrospective study of 708 eyes of 360 consecutive patients with IIH who had baseline optic disc photographs before or within 30 days of their diagnostic lumbar puncture and initiation of medical treatment. Read More

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December 2018

Visual function in children with primary brain tumors.

Curr Opin Neurol 2018 Dec 3. Epub 2018 Dec 3.

Departments of Ophthalmology and Pediatrics, Emory University, Atlanta, Georgia, USA.

Purpose Of Review: To review the recent advances in understanding how primary brain tumors affect vision in children.

Recent Findings: Children with primary brain tumors may have vision loss due to involvement of their afferent visual pathways or from papilledema. These vision deficits may go unrecognized until later in life, years after treatment of the primary lesion. Read More

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December 2018

HaNDL Syndrome: Case Report and Literature Review.

J Child Neurol 2018 Dec 5:883073818811546. Epub 2018 Dec 5.

1 Department of Pediatric Neurology, Massachusetts General Hospital, Boston, MA, USA.

Headache and Neurologic Deficits with cerebrospinal fluid Lymphocytosis (HaNDL) syndrome is a rare stroke mimicker characterized by moderate to severe headache temporally associated with transient neurologic deficits, typically hemiparesis, hemisensory disturbance, and/or aphasia. Cerebrospinal fluid studies reveal a lymphocytosis and elevated protein. Episodes recur over a period no longer than 3 months. Read More

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December 2018
1 Read

Reliable manifestations of increased intracranial pressure in patients with syndromic craniosynostosis.

J Craniomaxillofac Surg 2018 Nov 12. Epub 2018 Nov 12.

Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Purpose: Systematic examination of increased intracranial pressure (ICP) is important during the follow-up period after surgical repair of syndromic craniosynostosis. In these patients, postoperative progress can be unclear due to the involvement of multiple sutures and the high incidence of relapse due to the progressive nature of the disease and to genetic variability. In this study, we investigated the clinical manifestations of increased ICP in syndromic craniosynostosis patients before and after surgery. Read More

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November 2018
1 Read

Non-Syndromic Craniosynostosis Mimicking Primary Pseudotumor Cerebri Syndrome.

Headache 2018 Nov 25. Epub 2018 Nov 25.

Department of Pediatric Neurology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.

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November 2018
1 Read

Optic nerve disc veins inflammation (papillophlebitis) - case report.

Folia Med Cracov 2018 ;58(2):67-76

Voivodship Ophthalmic Hospital "Na Wzgórzach", os. Na Wzgórzach 17B, 31-723 Kraków, Poland.

Papillophlebitis is an uncommon disease in clinical practice. We would like to present a case of a 29-year-old patient with atypical orbital pain and flashings, presenting relative afferent pupillary defect and already typical of the disease entity: ophthalmoscopic picture of the fundus and big blind spot in perimetry. We present a complex and interdisciplinary diagnostic process that excludes general diseases such as hypertension, diabetes, coagulation disorders and neurological causes. Read More

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January 2018
9 Reads

Macular Hole After Poppers (Alkyl Nitrate) Inhalation in a Child.

Ophthalmic Surg Lasers Imaging Retina 2018 Nov;49(11):897-900

The authors present the first case of macular hole (MH) after a single inhalation of poppers. A 13-year-old girl presented with vision loss in the left eye (OS). Pediatric and neurology exams were normal. Read More

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November 2018
8 Reads

Pseudotumor cerebri and lung cancer-associated jugular vein thrombosis: Role of anatomical variations of torcular herophili.

eNeurologicalSci 2018 Dec 2;13:18-20. Epub 2018 Nov 2.

Laboratory of Neural Circuitry, Graduate School of Brain Science, Doshisha University, Japan.

A 71-year-old male appeared at the facility complaining of disturbance of consciousness and bilateral papilledema. The laboratory test revealed anemia and coagulation abnormality. A physical examination and magnetic resonance imaging (MRI) of the brain with and without gadolinium showed no abnormalities. Read More

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December 2018
1 Read

Stent Survival and Stent-Adjacent Stenosis Rates following Venous Sinus Stenting for Idiopathic Intracranial Hypertension: A Systematic Review and Meta-Analysis.

Interv Neurol 2018 Oct 31;7(6):490-500. Epub 2018 Jul 31.

Department of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.

Background: Idiopathic intracranial hypertension (IIH) is characterized by an elevated intracranial pressure without any identifiable causative factor such as an intracranial mass. Dural venous sinus stenosis (DVSS) has been suggested to be associated with IIH.

Objective: We performed an updated systematic review and meta-analysis to determine clinical outcomes as well as stent survival and stent-adjacent stenosis rates in patients undergoing DVSS for the management of medically refractory IIH. Read More

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October 2018
3 Reads

High-Risk Features of Delayed Clinical Progression in Cerebral Venous Thrombosis: A Proposed Prediction Score for Early Intervention.

Interv Neurol 2018 Oct 20;7(6):297-307. Epub 2018 Apr 20.

Department of Neurosurgery, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.

Background: Anticoagulation is the mainstay treatment for cerebral venous thrombosis (CVT). A subset of patients might deteriorate despite anticoagulation, and in such cases, endovascular therapy is recommended.

Methods: A retrospective review was performed on subjects with CVT from January 2005 to October 2016. Read More

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October 2018
1 Read

Multisuture Craniosynostosis and Papilledema in Pycnodysostosis: A Paradox?

J Craniofac Surg 2018 Nov 2. Epub 2018 Nov 2.

Oxford Craniofacial Unit.

Pycnodysostosis (PYCD) is a rare autosomal-recessive skeletal disorder that typically presents with osteosclerosis of the majority of the postcranial skeleton and osteolysis of the calvarium, manifesting as persistent open cranial fontanelles and widely spaced cranial sutures. Craniosynsostosis in PYCD is a somewhat paradoxical feature, and has only been rarely reported. The authors present a unique case of a 6-year-old girl with PYCD, multisuture craniosynostosis involving the coronal and sagittal sutures, severe obstructive sleep apnoea, and raised intracranial pressure presenting as papilledema. Read More

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November 2018
4 Reads

Bilambdoid and sagittal synostosis: Report of 39 cases.

Surg Neurol Int 2018 11;9:206. Epub 2018 Oct 11.

Craniofacial Unit, Department of Pediatric Neurosurgery, Hôpital Necker-Enfants Malades, Paris, France.

Background: Bilambdoid and sagittal synostosis (BLSS), also called "Mercedes Benz synostosis," is a multisutural craniosynostosis that has been described as a specific entity. However, this synostotic pattern can also be found in syndromic craniostenosis. To better define this entity we reviewed our experience with bilambdoid and sagittal synostosis. Read More

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October 2018
8 Reads

Neuro-Behcet's disease in a case with papilledema and intracranial hypertension as the initial presentation.

North Clin Istanb 2018 17;5(2):153-156. Epub 2018 Apr 17.

Department of Ophthalmology, Kartal Lütfü Kırdar Training and Research Hospital, Istanbul, Turkey.

A 27-year-old female presented to the Clinic of Ophthalmology with the complaints of photophobia, headache, and diplopia. An ophthalmological examination indicated that her best-corrected visual acuity was 20/20 in both eyes with decreased contrast sensitivity. Fundoscopic examination revealed bilateral papilledema. Read More

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Acute visual loss and optic disc edema followed by optic atrophy in two cases with deeply buried optic disc drusen: a mimicker of atypical optic neuritis.

BMC Ophthalmol 2018 Oct 26;18(1):278. Epub 2018 Oct 26.

Ocular Oftalmologia, Vitória, Brazil.

Background: Sudden visual loss and optic disc edema caused by optic neuritis (ON) is usually followed by significant visual recovery. However, little or no recovery occurs when the loss is caused by atypical ON, especially in patients with neuromyelitis optica (NMO). Optic disc drusen (ODD) is a cause of pseudo optic disc edema and may be a predisposing factor for non-arteritic anterior ischemic optic neuropathy (NAION), thereby mimicking atypical ON. Read More

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October 2018
7 Reads

Tuberous sclerosis complex: a clinical case with multiple ophthalmological manifestations.

BMJ Case Rep 2018 Oct 25;2018. Epub 2018 Oct 25.

Ophthalmology, Hospital Pedro Hispano, Matosinhos, Portugal.

The tuberous sclerosis complex is a rare disease, with autosomal dominant transmission, with multisystemic involvement including ophthalmologic. Retinal hamartomas and retinal achromic patch are the most frequent ocular findings. Other ophthalmic signs and symptoms are relatively rare in this disease. Read More

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October 2018
2 Reads

Spinal Ewing Sarcoma Metastatic to Bilateral Orbits.

Ophthalmic Plast Reconstr Surg 2018 Nov/Dec;34(6):e206-e208

Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, Connecticut.

A 39-year-old woman with primary spinal Ewing sarcoma and known lung metastases presented with painless bilateral decreased visual acuity over a 1-month period. Examination revealed bilateral disc edema. MRI of the brain/orbits showed metastatic lesions to the dura and bilateral orbits. Read More

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October 2018
5 Reads

Clinical Features of Pediatric Idiopathic Intracranial Hypertension and Applicability of New ICHD-3 Criteria.

Front Neurol 2018 28;9:819. Epub 2018 Sep 28.

Child Neurology Unit, Department of Neuroscience and Neurorehabilitation, Headache Center, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Idiopathic intracranial hypertension (IIH) is characterized by intracranial pressure >28 cmHO in the absence of identifiable causes. Aim of this paper is to describe the clinical phenotype of pediatric IIH and to analyze the applicability of ICHD-3 criteria in comparison to the ICHD-2. We conducted a retrospective analysis of full clinical data of pediatric patients diagnosed with IIH between January 2007 and June 2018. Read More

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September 2018
5 Reads

B-Mode Transorbital Ultrasonography for the Diagnosis of Idiopathic Intracranial Hypertension: A Systematic Review and Meta-Analysis.

Ultraschall Med 2018 Oct 22. Epub 2018 Oct 22.

Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.

In patients with idiopathic intracranial hypertension (IIH), transorbital sonography (TOS) may reveal an enlargement of the optic nerve sheath diameter (ONSD) and the presence of optic disc elevation (ODE), as a sign of an increase in intracranial pressure (ICP). We systematically reviewed the TOS findings in adults with IIH. MEDLINE, EMBASE, Cochrane Library and CENTRAL (1966 - May 2017) were searched to identify studies reporting data on patients with IIH assessed by B mode-TOS. Read More

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October 2018
3 Reads

Metastatic craniocervical hemangiopericytoma presenting with hydrocephalus and papilledema - Case review.

J Clin Neurosci 2018 Oct 30;56:186-187. Epub 2018 Jun 30.

Department of Neurosurgery, Level 1, Old Baker Building, The Alfred Hospital, 55 Commercial Rd, Melbourne, Victoria 3004, Australia. Electronic address:

Hemangiopericytomas are rare mesenchymal tumors with propensity to recur locally and metastasize. We report the unique case of a fifty-five-year-old male with recurrence of a previously resected craniocervical hemangiopericytoma presenting with obstructive hydrocephalus secondary to new metastatic cerebellar deposits. Emergent surgical resection of the cerebellar hemangiopericytomas was performed prior to adjuvant radiotherapy. Read More

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October 2018

New daily persistent headache (NDPH) triggered by a single Valsalva event: A case series.

Authors:
Todd D Rozen

Cephalalgia 2018 Oct 9:333102418806869. Epub 2018 Oct 9.

Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.

Objective To describe a new subtype of new daily persistent headache that is triggered by a single Valsalva event. Methods A case series of patients was evaluated in an academic headache clinic over a 3-year time period. Results A total of seven patients (four female and three male) were diagnosed with this new subtype of new daily persistent headache. Read More

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October 2018
10 Reads

Atypical Anti-MOG syndrome with aseptic meningoencephalitis and pseudotumor cerebri-like presentations.

Mult Scler Relat Disord 2018 Oct 3;27:30-33. Epub 2018 Oct 3.

UT Southwestern Medical Center, 5323 Harry Hines Blvd Dallas, Texas, TX 75235, United States.

Objective: To describe 2 atypical cases with Anti-MOG antibody related demyelinating syndrome.

Methodology: Case series.

Results: We present two cases. Read More

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October 2018
2 Reads

Obstructive Sleep Apnea in Neuro-Ophthalmology.

J Neuroophthalmol 2018 Oct 8. Epub 2018 Oct 8.

Save Sight Institute, Discipline of Ophthalmology, Faculty of Medicine and Health Sciences, University of Sydney, Sydney, Australia; Department of Ophthalmology, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

Background: Obstructive sleep apnea (OSA) is a common pulmonary disorder with many systemic sequelae. Its association with diseases seen in neuro-ophthalmology is being increasingly recognized. Treatment of OSA with continuous positive airway pressure (CPAP) may reverse the pathology in some eye diseases. Read More

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October 2018
2 Reads
1.810 Impact Factor

Lower body negative pressure to safely reduce intracranial pressure.

J Physiol 2018 Oct 4. Epub 2018 Oct 4.

Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Dallas, Dallas, TX, USA.

Key Points: During long-term missions, some astronauts experience structural and functional changes of the eyes and brain which resemble signs/symptoms experienced by patients with intracranial hypertension. Weightlessness prevents the normal cerebral volume and pressure 'unloading' associated with upright postures on Earth, which may be part of the cerebral and ocular pathophysiology. By placing the lower body in a negative pressure device (LBNP) that pulls fluid away from cranial compartments, we simulated effects of gravity and significantly lowered pressure within the brain parenchyma and ventricle compartments. Read More

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October 2018
27 Reads

Co-occurrence of acute ophthalmoplegia (without ataxia) and idiopathic intracranial hypertension.

Eur J Ophthalmol 2018 Oct 3:1120672118803532. Epub 2018 Oct 3.

University of Malaya, Kuala Lumpur, Malaysia.

Background: Acute ophthalmoparesis without ataxia was designated as 'atypical Miller Fisher syndrome' as it presents with progressive, relatively symmetrical ophthalmoplegia, but without ataxia nor limb weakness, in the presence of anti-GQ1b antibody. Idiopathic intracranial hypertension is characterized by signs of raised intracranial pressure occurring in the absence of cerebral pathology, with normal composition of cerebrospinal fluid and a raised opening pressure of more than 20 cmHO during lumbar puncture. We aim to report a rare case of acute ophthalmoplegia with co-occurrence of raised intracranial pressure. Read More

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October 2018
3 Reads

Early Macular Vessel Density Loss in Acute Ischemic Optic Neuropathy Compared to Papilledema: Implications for Pathogenesis.

Transl Vis Sci Technol 2018 Sep 26;7(5):10. Epub 2018 Sep 26.

Department of Ophthalmology, University of Colorado, School of Medicine, Aurora, CO, USA.

Purpose: This study compares macular and parafoveal vasculature in patients with optic disc swelling.

Methods: Twenty eyes with acute nonarteritic anterior ischemic optic neuropathy (NAION), 39 eyes with papilledema at first presentation, and 22 eyes of normal subjects were imaged using optical coherence tomography angiography (OCT-A). Macular ganglion cell complex (GCC) and peripapillary retinal nerve fiber layer thicknesses were measured in addition to macula and parafovea superficial and deep vasculature. Read More

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September 2018
7 Reads

Cases of visual impairment caused by cerebral venous sinus occlusion-induced intracranial hypertension in the absence of headache.

BMC Neurol 2018 Sep 29;18(1):159. Epub 2018 Sep 29.

Department of Ophthalmology, Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing, China.

Background: Cerebral venous sinus thrombosis or stenosis (here collectively referred to as cerebral venous sinus occlusion, CVSO) can cause chronically-elevated intracranial pressure (ICP). Patients may have no neurological symptoms other than visual impairment, secondary to bilateral papilledema. Correctly recognizing these conditions, through proper ophthalmological examination and brain imaging, is very important to avoid delayed diagnosis and treatment. Read More

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September 2018
2 Reads

Early Loss of Optic Cup with Increased Intracranial Pressure.

Neuroophthalmology 2018 Oct 9;42(5):295-298. Epub 2018 Jan 9.

Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

A 54-year-old woman developed increased intracranial pressure due to chronic dural venous sinus thrombosis in the absence of significant comorbidity. In the years preceding diagnosis, the patient underwent routine diabetic retinopathy screening; however, gradual loss of optic cup and disc swelling was only retrospectively noted after marked papilloedema was evident at an optometry visit. The patient made a full recovery once the diagnosis was established. Read More

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October 2018

Endovascular Treatment for Venous Sinus Stenosis in Idiopathic Intracranial Hypertension: An Observational Study of Clinical Indications, Surgical Technique, and Long-Term Outcomes.

World Neurosurg 2018 Sep 21. Epub 2018 Sep 21.

Norton Neuroscience Institute, Norton Healthcare, Louisville, Kentucky, USA. Electronic address:

Background: Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure. IIH causes significant morbidity marked by incapacitating headaches and visual disturbances. This study investigated the long-term outcomes of venous sinus stenting in a large group of patients with IIH. Read More

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September 2018
2.420 Impact Factor

Atypical clinical manifestations of Miller Fisher syndrome.

Neurol Sci 2018 Sep 19. Epub 2018 Sep 19.

Department of Neurology, Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Kumo-ro 20, Beomo-ri, Mulgum-eup, Yangsan, Gyeongnam, 626-770, South Korea.

Miller Fisher syndrome (MFS) is characterized by a clinical triad of ophthalmoplegia, ataxia, and areflexia, and is closely associated with serum anti-GQ1b antibody. Although the clinical triad is the cardinal diagnostic clue, a variety of other symptoms and signs beyond the triad have been reported. To elucidate the frequency and characteristics of atypical clinical manifestations of MFS, we recruited 38 patients with MFS and evaluated the symptoms or signs beyond the classic triad. Read More

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September 2018

Primary Leptomeningeal Oligodendroglioma, IDH-Mutant, 1p/19q-Codeleted.

Front Neurol 2018 27;9:700. Epub 2018 Aug 27.

Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.

We present a case of a 43-year-old woman with a history of headaches and blurry vision. Ophthalmologic examination identified papilledema. MR imaging demonstrated a right parietal region mass with patchy areas of contrast enhancement and focal calcifications. Read More

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August 2018
7 Reads

Endovascular Treatment of Idiopathic Intracranial Hypertension with Stenting of the Transverse Sinus Stenosis.

Neurointervention 2018 Sep 1;13(2):138-143. Epub 2018 Oct 1.

Department of Neurosurgery and Endovascular Therapy, Osaka Medical College, Takatsuki, Japan.

For many years, the pathophysiology of idiopathic intracranial hypertension (IIH) was interpreted as "secondary intracranial hypertension," and IIH was considered to be caused by brain edema due to obstructive sleep apnea. Another theory proposed cerebrospinal fluid (CSF) absorption impairment due to excessive medication with vitamin A derivatives. Other reports pointed out the importance of obesity, which may cause an impairment of intracranial venous drainage due to elevated right atrial pressure. Read More

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September 2018
1 Read

Intracranial hypertension: a current review.

Curr Opin Pediatr 2018 Dec;30(6):764-774

Department of Neurology, Nationwide Children's Hospital, Columbus, Ohio, USA.

Purpose Of Review: To provide a current review of recent publications with regards to intracranial hypertension.

Recent Findings: Attempts were made to provide pediatric data; however, the recent completion of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) has provided a wealth of data with regards to adult intracranial hypertension.The pediatric incidence of intracranial hypertension ranges between 0. Read More

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December 2018
9 Reads

Is it always cancer? A curious case of benign intracranial hypertension in chronic myeloid leukemia.

Intractable Rare Dis Res 2018 Aug;7(3):182-184

Department of Hematology/Oncology, JFK medical Center, Fl, USA.

28-year-old African American female with chronic myeloid leukemia (CML) presented with blurry vision for 4-5 days prior to presentation associated with right-sided headaches. Patient was on treatment for the CML but never had hematological remission. Patient saw an ophthalmologist who told her that she has bilateral optic disc swelling and advised her to get an MRI of the brain. Read More

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August 2018
2 Reads

An investigation on optic nerve head involvement in Fuchs uveitis syndrome using optical coherence tomography and fluorescein angiography.

Graefes Arch Clin Exp Ophthalmol 2018 Dec 3;256(12):2421-2427. Epub 2018 Sep 3.

Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 13352, Iran.

Purpose: To investigate optic nerve head involvement in patients with Fuchs uveitis syndrome (FUS).

Methods: Optic nerve head of 43 FUS eyes without clinical optic disc edema and 37 unaffected fellow eyes were evaluated using optical coherence tomography (OCT) of peripapillary retina and retinal nerve fiber layer (RNFL) and fundus fluorescein angiography.

Results: Seventy-one percent of FUS eyes showed optic nerve head hyperfluorescence. Read More

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December 2018
6 Reads

Cystic Degeneration of Craniofacial Fibrous Dysplasia.

World Neurosurg 2018 Dec 31;120:159-162. Epub 2018 Aug 31.

Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Erasmus Medical Center and Sophia Children's Hospital, Rotterdam, The Netherlands.

Background: Fibrous dysplasia (FD) is most often a slowly progressive benign disease in which the normal bone structure is replaced by fibrous and osteoid tissue.

Case Description: A 16-year-old adolescent, known with FD in the sphenoid bone, suffered an acute decreased visual acuity with papilledema on the left eye. The radiologic images were best compatible with cystic degeneration of the known FD with optic nerve compression in the optic canal. Read More

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December 2018
7 Reads

[Diabetic papillopathy after intensification of insulin therapy: A case report].

Rev Med Interne 2018 Aug 30. Epub 2018 Aug 30.

Service d'endocrinologie, hôpital La Rabta, faculté de médecine de Tunis, université Tunis, El Manar, Tunisie.

Introduction: Diabetic papillopathy is a rare ocular complication of diabetes. Its pathophysiology is not well known. It is a unilateral or bilateral optic disc edema with variable degrees of visual loss. Read More

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August 2018
6 Reads

An update of idiopathic intracranial hypertension.

Curr Opin Ophthalmol 2018 Nov;29(6):495-502

Department of Neuro-ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.

Purpose Of Review: We aim to provide a comprehensive and updated review on idiopathic intracranial hypertension (IIH), including the most current studies and treatment options. Special focus will be put on recent theories about the pathophysiology, and on newer prospective studies on treatment modalities.

Recent Findings: The Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) provided evidence supporting acetazolamide as a well tolerated first-line therapy in IIH patients with mild vision loss. Read More

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November 2018
10 Reads

Wall-eyed Bilateral Internuclear Ophthalmoplegia (WEBINO) in a Patient With Idiopathic Intracranial Hypertension.

Neurologist 2018 Sep;23(5):157-159

Neurology, AZ Maria Middelares.

Introduction: Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) is a variant syndrome of internuclear ophthalmoplegia, consisting of primary gaze exotropia, adduction impairment, nystagmus of the abducting eye, and vertical gaze-evoked nystagmus. It seems to be most frequently associated with multiple sclerosis, although other etiologies such as brainstem ischemia or hydrocephalus have also been described.

Case Report: We report the case of a 25-year-old woman who presented with subacute progressive oculomotor disturbances, resulting in the development of a WEBINO over a few days. Read More

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September 2018
15 Reads

Venous sinus stenting for idiopathic intracranial hypertension: a systematic review and meta-analysis.

J Neurointerv Surg 2018 Aug 30. Epub 2018 Aug 30.

Joint Division of Medical Imaging, Department of Medical Imaging, UHN, University of Toronto, Toronto, Ontario, Canada.

Background: Stenting of the intracranial venous sinuses is used as a treatment in certain cases of idiopathic intracranial hypertension (IIH). Interest in, and experience of, this technique is growing, particularly in recent years. We sought to provide an updated systematic review and meta-analysis of the use of venous stenting in these patients, examining clinical outcomes. Read More

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August 2018
2 Reads

Evaluation and management of adult idiopathic intracranial hypertension.

Pract Neurol 2018 Dec 28;18(6):485-488. Epub 2018 Aug 28.

Metabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.

This paper summarises the first consensus guidelines for idiopathic intracranial hypertension as an infographic. Following a systematic literature review, a multidisciplinary specialist interest group met and established questions relating to population, interventions, controls and outcomes (PICO). A survey was sent to doctors who manage idiopathic intracranial hypertension (IIH) regularly. Read More

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December 2018
8 Reads

Visual Field Mean Deviation at Diagnosis of Idiopathic Intracranial Hypertension Predicts Visual Outcome.

J Neuroophthalmol 2018 Aug 24. Epub 2018 Aug 24.

Departments of Ophthalmology and Visual Sciences (SM, JDT, WTC, LDL) and Neurology (JDT, WTC, LDL), University of Michigan, Ann Arbor, Michigan.

Background: A robust predictor of visual outcome in idiopathic intracranial hypertension (IIH) would be useful in management, but there is limited information on this point. The purpose of this study was to ascertain whether visual field mean deviation on standard static perimetry performed at diagnosis in a large patient cohort is a reliable predictor of visual outcome.

Methods: We retrospectively reviewed the automated visual field mean deviations at diagnosis and at final encounter in 79 patients with IIH examined in the neuro-ophthalmology clinics at a single academic medical center from 1999 to 2015. Read More

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August 2018
12 Reads

Neuroretinitis: a review.

Curr Opin Ophthalmol 2018 Nov;29(6):514-519

Department of Ophthalmology, Edward Harkness Eye Institute, Columbia University, New York, New York, USA.

Purpose Of Review: Neuroretinitis is an inflammatory disorder of the eye presenting with optic disc edema and the delayed development of a macular star secondary to optic nerve swelling toward the macular structures. Neuroretinitis can be divided into idiopathic, infectious (including neuroretinitis associated with cat scratch disease) and recurrent.

Recent Findings: The clinical presentation of neuroretinitis includes impaired visual acuity, dyschromatopsia, relative afferent pupillary defects and visual field abnormalities - particularly cecocentral and central scotomas. Read More

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November 2018
5 Reads

Ophthalmological findings in neuroborreliosis - a prospective study performed in western Sweden.

Acta Ophthalmol 2018 Aug 26. Epub 2018 Aug 26.

Department of Ophthalmology, Sahlgrenska University Hospital, Mölndal, Sweden.

Purpose: To evaluate and follow-up ophthalmological findings in individuals diagnosed with neuroborreliosis, confirmed by cerebrospinal fluid (CSF) analysis.

Methods: Twenty-four individuals (13 males), mean age 43.5 ± 18. Read More

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August 2018
4 Reads