6,655 results match your criteria Papilledema


Spontaneous Intracranial Hypotension Followed by Intracranial Hypertension.

Neurologist 2020 Jul;25(4):109-111

Departments of Neurology.

Introduction: Spontaneous intracranial hypotension is a secondary cause of headache caused by suspected cerebrospinal fluid leaks. It is associated with vascular changes that may predispose to superficial siderosis. When treated with an epidural blood patch, rebound intracranial hypertension may ensue. Read More

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http://dx.doi.org/10.1097/NRL.0000000000000285DOI Listing

Perioperative mannitol intensive use may avoid the early complication of cerebral venous sinus stenting.

Ann Transl Med 2020 Jun;8(11):672

Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.

Background: Cerebral venous sinus (CVS) stenting has been widely applied for correcting CVS stenosis. However, there are still some potential complications. The purpose of this study is to investigate the impact of perioperative management on avoiding complications of CVS stenting. Read More

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http://dx.doi.org/10.21037/atm-20-3021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327372PMC

An Update on Imaging in Idiopathic Intracranial Hypertension.

Front Neurol 2020 10;11:453. Epub 2020 Jun 10.

Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Neuroimaging plays an essential role in the diagnostic workup of idiopathic intracranial hypertension with the aims to exclude secondary causes of elevated intracranial pressure and to identify imaging signs that are commonly observed in this disorder. As a valuable expansion of brain imaging, the imaging of the retina using optical coherence tomography has been of increasing value. In particular, this is the case with the latest devices that allow a more accurate distinction between a reduction in retinal nerve fiber layer thickness due to an improvement of papilledema or due to a worsening caused by optic nerve atrophy. Read More

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http://dx.doi.org/10.3389/fneur.2020.00453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297913PMC

Crouzon Syndrome in a Ten-week-old Infant: A Case Report.

Saudi J Med Med Sci 2020 May-Aug;8(2):146-150. Epub 2020 Apr 17.

Department of Surgery, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

Crouzon syndrome is a rare genetic disorder. We report a rare case of Crouzon syndrome in a very young infant with distinct features of craniofacial malformations. A 10-week-old male child presented with features of craniofacial dysostosis with abnormal shape of the skull, proptosis, hypertelorism, curved nose and frontal bossing. Read More

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http://dx.doi.org/10.4103/sjmms.sjmms_38_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305672PMC

Multimodal Imaging of Optic Nerve Drusen in a 10-year Hyperopic Child.

J Coll Physicians Surg Pak 2020 May;30(5):541-542

Department of Ophthalmology, University of Health Sciences, Beyoglu Eye Training and Research Hospital Istanbul, Turkey.

Optic nerve drusen (OND) are abnormal calcified acellular deposits located within the prelaminar portion of the optic nerve. They are usually asymptomatic and detected incidentally during fundoscopic examination. They have a clinical significance due to their appearance which mimicks true papilledema, if the drusen are buried. Read More

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http://dx.doi.org/10.29271/jcpsp.2020.05.541DOI Listing

[Differential diagnosis of papilledema and macular exudation-the exophytically growing juxtapapillary retinal capillary hemangioma].

Ophthalmologe 2020 Jun 23. Epub 2020 Jun 23.

Augenzentrum am St. Franziskus-Hospital, Hohenzollernring 74, 48145, Münster, Deutschland.

In a 38-year-old female patient, who had been treated for acute visual impairment and suspected optic neuritis with no organic evidence in the right eye, an exophytically growing juxtapapillary retinal capillary hemangioma was found. The benign tumor is a rare but important differential diagnosis in cases of papilledema and macular exudation. The treatment is difficult; various therapeutic concepts are discussed. Read More

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http://dx.doi.org/10.1007/s00347-020-01138-xDOI Listing

A rare case of schwannoma arising from dura mater of the petrosal surface in the posterior cranial fossa.

World Neurosurg 2020 Jun 19. Epub 2020 Jun 19.

Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Background: An intracranial schwannoma originating in the dura mater is extremely rare. Herein, we report a case of schwannoma arising from the dura mater of the petrosal surface in the posterior cranial fossa.

Case Description: A 48-year-old man presented with slight gait disturbance and papilledema. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.06.078DOI Listing

Quantitative topographic curvature maps of the posterior eye utilizing optical coherence tomography.

Retina 2020 Jun 17. Epub 2020 Jun 17.

Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710.

Purpose: Deformations of the retina such as staphylomas in myopia or scleral flattening in high intracranial pressure can be challenging to quantify with en face imaging. We describe an OCT based method for the generation of quantitative posterior eye topography maps in normal and pathologic eyes.

Methods: Utilizing "whole eye" OCT we corrected for subjects' optical distortions to generate spatially accurate posterior eye OCT volumes and created local curvature (KM, mm) topography maps for each consented subject. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002897DOI Listing

Optic nerve sheath fenestration via a supero-medial eyelid skin crease approach for the treatment of idiopathic intracranial hypertension in a UK population.

Eye (Lond) 2020 Jun 17. Epub 2020 Jun 17.

Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, S10 2JF, UK.

Background/aims: Optic nerve sheath fenestration (ONSF) is a surgical intervention in the management of idiopathic intracranial hypertension (IIH) infrequently performed in the United Kingdom. Numerous surgical approaches have been described, including medial transconjunctival, lateral and endoscopic. We describe our outcomes and complications from ONSF via a supero-medial eyelid skin crease incision in patients with IIH. Read More

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http://dx.doi.org/10.1038/s41433-020-1024-8DOI Listing

Spontaneous Skull Base Cerebrospinal Fluid Leaks and Their Relationship to Idiopathic Intracranial Hypertension.

Am J Rhinol Allergy 2020 Jun 19:1945892420932490. Epub 2020 Jun 19.

Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.

Background: The association between spontaneous skull base cerebrospinal fluid (CSF) leaks and idiopathic intracranial hypertension (IIH) has been suggested, but its significance remains unclear.

Objective: To estimate the prevalence of IIH in spontaneous skull base CSF leak patients.

Methods: Systematic collection of demographics, neuro-ophthalmic and magnetic resonance imaging evaluation of spontaneous skull base CSF leak patients seen pre- and post-leak repair in one neuro-ophthalmology service. Read More

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http://dx.doi.org/10.1177/1945892420932490DOI Listing

Cryptococcal meningitis in an immunocompetent patient.

Am J Emerg Med 2020 Jun 6. Epub 2020 Jun 6.

Department of Emergency Medicine, Vanderbilt University Medical Center, 1313 21st Ave, South, 703 Oxford House, Nashville, TN 37232-4700, United States of America.

Cryptococcal meningitis is a fungal infection that is most commonly thought of as an opportunistic infection affecting immunocompromised patients, classically patients with Human Immunodeficiency (HIV) infection. It is associated with a variety of complications including disseminated disease as well as neurologic complications including intracranial hypertension, cerebral infarcts, vision loss and other neurologic deficits. It is diagnosed by lumbar puncture with CSF studies, including fungal culture and cryptococcal antigen testing. Read More

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http://dx.doi.org/10.1016/j.ajem.2020.05.115DOI Listing

Subacute transverse myelitis with optic symptoms in neuroborreliosis: a case report.

BMC Neurol 2020 Jun 13;20(1):244. Epub 2020 Jun 13.

Department of Oral Surgery, Medical University of Gdansk, Gdansk, Poland.

Background: Subacute transverse myelitis is one of the late manifestations of neuroborreliosis with only a few cases described to the present day.

Case Presentation: We present magnetic resonance imaging, cerebrospinal fluid, and electroneurography findings of a young female patient suffering from neuroborreliosis-associated transverse myelitis with a wide constellation of symptoms including papilloedema. Magnetic resonance imaging of the cervical spine has shown an enlargement of the spinal cord in the mid-cervical region. Read More

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http://dx.doi.org/10.1186/s12883-020-01816-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293114PMC

Asymptomatic Papilledema in a 64-Year-Old Man.

JAMA Ophthalmol 2020 Jun 11. Epub 2020 Jun 11.

Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamaophthalmol.2020.0875DOI Listing

Neuroendovascular Cerebral Sinus Stenting in Idiopathic Intracranial Hypertension.

Interv Neurol 2020 Jan 4;8(2-6):164-171. Epub 2019 Jun 4.

Department of Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey, USA.

Idiopathic intracranial hypertension (IIH) is a rare, ill-understood disease of significant morbidity. Because the pathophysiology is poorly understood, treatment protocols are not uniform and are directed towards alleviating the most common symptoms: headache and visual loss. In this review, we analyze 25 case series, all of which included IIH patients ( = 408) who were treated with placement of a venous sinus stent. Read More

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http://dx.doi.org/10.1159/000500051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253862PMC
January 2020

Not Just Another Headache: Cerebral Venous Sinus Thrombosis in a Patient With Isolated Antithrombin III Deficiency.

Cureus 2020 May 31;12(5):e8383. Epub 2020 May 31.

Internal Medicine, Kirksville College of Osteopathic Medicine, A. T. Still University, Kirksville, USA.

Cerebral venous sinus thrombosis (CVST) is a rare condition. Symptoms and signs arise from a combination of thrombosis of cerebral veins and increased intracranial pressure. The most common presenting symptom is a non-descriptive headache, but presentation varies with underlying etiology. Read More

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http://dx.doi.org/10.7759/cureus.8383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265752PMC

Cerebellar hemangioblastoma during pregnancy: Management options and review of literature.

Surg Neurol Int 2020 23;11:123. Epub 2020 May 23.

Department of Neurosurgery, All India Institute of Medical Science, Raipur, Chhattisgarh, India.

Background: Symptomatic cerebellar hemangioblastomas are extremely rare in pregnant women and the ideal management is not well established. In the present article, we aimed to report a case of large cerebellar hemangioblastoma complicated by pregnancy and managed successfully by surgical resection. In addition, we also discuss management options and review of the current literature pertaining to this pathology. Read More

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http://dx.doi.org/10.25259/SNI_203_2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265369PMC

Etiology of Papilledema in Patients in the Eye Clinic Setting.

JAMA Netw Open 2020 Jun 1;3(6):e206625. Epub 2020 Jun 1.

Department of Ophthalmology, Mayo Clinic College of Medicine, Rochester, Minnesota.

Importance: The study of health conditions associated with papilledema will augment the clinical judgment of eye care professionals treating patients with optic disc edema in determining the urgency of additional evaluation and counseling patients accordingly.

Objectives: To determine the incidence, demographic characteristics, and etiologies of papilledema based on a unique records-linkage research platform; and to describe the demographic and clinical differences between patients with idiopathic intracranial hypertension (IIH) and other causes of papilledema.

Design, Setting, And Participants: Retrospective population-based cross-sectional study of patients treated for papilledema at outpatient eye clinics in Olmsted County, Minnesota, using the Rochester Epidemiology Project. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2020.6625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267843PMC

Reductions in bilateral transverse sinus pressure gradients with unilateral transverse venous sinus stenting for idiopathic intracranial hypertension.

J Neurointerv Surg 2020 Jun 1. Epub 2020 Jun 1.

Radiology, Mayo Clinic, Rochester, MN, United States

Background: Venous sinus stenting is an effective treatment for papilledema associated with idiopathic intracranial hypertension (IIH). It is unclear whether unilateral transverse-sigmoid sinus (TSS) stenting adequately decompresses the contralateral TSS system in cases of bilateral transverse sinus stenosis. The objective of this study was to compare changes in bilateral TSS pressure gradients following unilateral TSS stenting in a series of patients with IIH. Read More

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http://dx.doi.org/10.1136/neurintsurg-2020-016170DOI Listing

Unusual presentation of idiopathic intracranial hypertension.

BMJ Case Rep 2020 May 31;13(5). Epub 2020 May 31.

Mercy Health Hauenstein Neuroscience Center, Mercy Health Saint Mary's, Grand Rapids, Michigan, USA.

Idiopathic intracranial hypertension typically presents with holocephalic headache associated with nausea, vomiting and bilateral papilledema. Involvement of the sixth cranial nerve is relatively common. The involvement of other cranial nerves, however, is rare in this disorder. Read More

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http://dx.doi.org/10.1136/bcr-2020-234741DOI Listing

Effect of Shunting on Visual Outcomes and Headache in Patients with Idiopathic Intracranial Hypertension.

World Neurosurg 2020 May 28. Epub 2020 May 28.

Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital forNeuroscience, Philadelphia, Pennsylvania, USA. Electronic address:

Background: Visual dysfunction and headache are major symptoms in patients with idiopathic intracranial hypertension (IIH).

Objective: We aim to evaluate the improvement of these symptoms in patients who underwent ventriculoperitoneal (VPS) and lumboperitoneal (LPS) shunting.

Methods: Electronic medical records were reviewed to identify baseline and treatment characteristics for patients diagnosed with IIH over ten years. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.05.186DOI Listing
May 2020
2.417 Impact Factor

[Neuro-ophthalmologic emergencies during this COVID-19 pandemic].

J Fr Ophtalmol 2020 Jun 30;43(6):550-551. Epub 2020 Apr 30.

Fondation Ophtalmologique de Rothschild, 29, rue Manin, 75019 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jfo.2020.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190527PMC

Cerebral Venous Sinus Thrombosis Associated with Dutasteride Use.

Yonsei Med J 2020 Jun;61(6):553-555

Department of Neurology, Gangnam Severance Hospital, Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, Korea.

Cerebral venous thrombosis (CVT) is an uncommon cause of stroke that mainly affects young adults with known risk factors of prothrombotic conditions, pregnancy, infection, malignancy, and drugs. Dutasteride is a 5α-reductase inhibitor that is used for benign prostate hypertrophy and androgenetic alopecia. To date, CVT caused by dutasteride use has not been reported. Read More

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http://dx.doi.org/10.3349/ymj.2020.61.6.553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255996PMC

Papilledema in Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Pediatric Case and Review of the Literature.

J Child Neurol 2020 May 29:883073820925302. Epub 2020 May 29.

Department of Child Neurology, State University of New York at Downstate, Brooklyn, NY, USA.

Objective: To analyze the available literature on papilledema in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), report the first detailed pediatric case, and explore the underlying pathophysiology.

Methods: First, we conducted a comprehensive literature review of all cases of papilledema in CIDP. Next, we reviewed each case, incorporating only those including cerebrospinal fluid analysis into the results. Read More

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http://dx.doi.org/10.1177/0883073820925302DOI Listing

An update on idiopathic intracranial hypertension in adults: a look at pathophysiology, diagnostic approach and management.

J Neurol 2020 May 27. Epub 2020 May 27.

Department "GF Ingrassia", Section of Neurosciences, University of Catania, Via Santa Sofia 78, 95123, Catania, Italy.

Idiopathic intracranial hypertension is a neurological syndrome determined by a rise in intracranial pressure without a detectable cause. Course and prognosis may be changeable, requiring a multidisciplinary approach for its diagnosis and management. Although its precise pathogenesis is still unknown, many studies have been carried out to define the possible causal and associated factors, such as retinoids, steroid hormones, body mass index and recent weight gains, cytokines and adipokines levels. Read More

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http://dx.doi.org/10.1007/s00415-020-09943-9DOI Listing

The prevalence of papilledema in patients with migraine: a crucial cooccurrence of migraine and idiopathic intracranial hypertension.

Neurol Sci 2020 May 26. Epub 2020 May 26.

Department of Ophthalmology, Yozgat City Hospital, Yozgat, Turkey.

Objective: We aimed to investigate the prevalence of idiopathic intracranial hypertension (IIH) in patients with migraine by screening for papilledema.

Materials And Methods: We have included all the patients with migraine who applied to our neurology clinic during December 2019 and accepted to participate in the study. The demographic and clinical characteristics including migraine subtype (episodic/chronic), headache frequency per month, and headache characteristics of all patients were interrogated. Read More

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http://dx.doi.org/10.1007/s10072-020-04473-8DOI Listing

Surprise of Behcet's disease in a patient with bilateral disc oedema and the role of OCT.

BMJ Case Rep 2020 May 21;13(5). Epub 2020 May 21.

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Behcet's disease is a multisystem vasculitis which can be associated with cerebral venous thrombosis (CVT) leading to increased intracranial tension and papilloedema. We report a case of a 17-year-old boy who presented to us with inward deviation of right eye with bilateral disc oedema and on further investigations was found to be Human Leukocyte Antigen (HLA) B5 positive, along with CVT on magnetic resonance venography which further led us to the diagnosis of non-parenchymal neuro-Behcet's. Read More

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http://dx.doi.org/10.1136/bcr-2020-234693DOI Listing

Clival Chordoma in an Adolescent: A Perspective from Primary Care.

Korean J Fam Med 2020 May 22. Epub 2020 May 22.

Department of Primary Care Medicine, Faculty of Medicine, Universiti Teknologi MARA, Batu Caves, Selangor, Malaysia.

Clival chordoma is a rare malignant tumor of the brain that typically occurs in older adults. It has a high local recurrence rate and is hence associated with poor prognosis. Here, we report a case of an adolescent who presented with a 1-month history of worsening headache and blurring of vision, as well as a 6-month history of left-sided facial and body numbness. Read More

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http://dx.doi.org/10.4082/kjfm.19.0004DOI Listing

Senior-Løken syndrome and intracranial hypertension.

Ophthalmic Genet 2020 May 20:1-4. Epub 2020 May 20.

Department of Ophthalmology Faculty of Medical and Health Sciences, New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand.

Senior-Løken syndrome (SLS) is a rare autosomal recessive disease characterised by nephronophthisis and retinal degeneration, and belongs to a group of genetically heterogeneous disorders known as the ciliopathies. Case report of a  patient with genetically proven SLS presenting with headaches and swollen optic nerve heads, review of medical notes and ophthalmic imaging, with retinal photography, fundus autofluorescence, and OCT retinal nerve fibre layer analysis. We present findings in a 15 year old girl with Senior-Løken syndrome associated with compound heterozygous mutations in the gene,  who initially presented with a retinal dystrophy, and subsequent renal failure requiring renal transplantation and immunosuppression. Read More

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http://dx.doi.org/10.1080/13816810.2020.1766086DOI Listing

Reliability of optic disc edema area in estimating the severity of papilledema in patients with POEMS syndrome.

Orphanet J Rare Dis 2020 May 19;15(1):116. Epub 2020 May 19.

Department of Hematology, Peking Union Medical College Hospital , Chinese Academy of Medical Sciences, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, 100730, China.

Background: Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes (POEMS) syndrome is a rare paraneoplastic syndrome involving multisystem. Optic disc edema (ODE) is the most common ocular manifestation in patients with POEMS syndrome and serves as an independent prognostic factor. However, parameters previously used to estimate its severity were inconvenient and costly. Read More

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http://dx.doi.org/10.1186/s13023-020-01392-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238582PMC

Update in Pediatric Pseudotumor Cerebri Syndrome.

Authors:
Shannon J Beres

Semin Neurol 2020 Jun 18;40(3):286-293. Epub 2020 May 18.

Department of Neurology and Ophthalmology, Stanford University, Palo Alto, California.

Pseudotumor cerebri syndrome (PTCS) is a rare condition in children presenting with headache and papilledema from increased intracranial pressure that can cause significant morbidity. This can be idiopathic, also known as idiopathic intracranial hypertension or primary intracranial hypertension, or can be secondary to medications and associated medical conditions. Given the threat to vision, early detection and treatment is needed in all age groups. Read More

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http://dx.doi.org/10.1055/s-0040-1708847DOI Listing

Idiopathic Intracranial Hypertension: Contemporary Management and Endovascular Techniques.

Semin Intervent Radiol 2020 Jun 14;37(2):175-181. Epub 2020 May 14.

Department of Radiology, University of Colorado School of Medicine, Aurora, Colorado.

Idiopathic intracranial hypertension (IIH) is a disease process of abnormally increased intracranial pressure in the absence of a mass lesion. Medical management, optic nerve fenestration, and surgical shunting procedures have failed to produce consistently successful results. In an unknown percentage of cases, IIH is caused by dural venous sinus obstruction which can be cured by endovascular treatment with dural venous sinus stent placement. Read More

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http://dx.doi.org/10.1055/s-0040-1709172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224981PMC

Evaluation of Clinical Profile, Diagnostic Tests, And Prognosis of Cryptococcal Meningitis in HIV Infected Patients in Western India.

Infect Disord Drug Targets 2020 May 16. Epub 2020 May 16.

Junior Resident, Department of Medicine, All India Institutes of Medical Sciences Jodhpur, Rajasthan. India.

Background: Cryptococcal meningitis is a dreaded complication in HIV infected patients. It was associated with high mortality and morbidity before the advent of Highly Active Anti-Retroviral Therapy. A study was planned in our institute to evaluate the clinical profile, laboratory findings, and prognostic factors for survival in these patients. Read More

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http://dx.doi.org/10.2174/1567201817666200516160432DOI Listing

Long-term outcome of large sylvian arachnoid cysts: the role of surgery has been exaggerated.

J Neurosurg Pediatr 2020 May 15:1-7. Epub 2020 May 15.

1Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul.

Objective: The surgical indications for some arachnoid cysts (ACs) are controversial. While surgical procedures can be effective when an AC is a definite cause of hydrocephalus or papilledema, most ACs do not cause any symptoms or signs. Some surgeons perform several procedures to treat ACs because of their large size. Read More

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http://dx.doi.org/10.3171/2020.3.PEDS19574DOI Listing

Cerebral Venous Sinus Thrombosis in Adults with Prothrombotic Conditions: A Systematic Review and a Case from Our Institution.

Cureus 2020 Apr 12;12(4):e7654. Epub 2020 Apr 12.

Internal Medicine, Creighton University Arizona Health Education Alliance/Valleywise Health Medical Center, Phoenix, USA.

Cerebral venous sinus thrombosis (CVST) is a rare condition characterized by elevated intracranial pressure due to impaired cerebral venous drainage, potentially leading to life-threatening consequences. We searched the PubMed electronic database for 'cerebral venous sinus thrombosis' and 'prothrombotic' cases reported in adults (19+ years) and conducted a systematic review for the published literature in the English language pooled with a case from our institution. Data were analyzed regarding patient demographics, risk factors, clinical features, treatment modalities, and outcomes when available. Read More

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http://dx.doi.org/10.7759/cureus.7654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217592PMC

Outcome of idiopathic intracranial hypertension after laparoscopic sleeve gastrectomy.

Surg Obes Relat Dis 2020 Apr 11. Epub 2020 Apr 11.

Ophthalmology Department, Alexandria University Faculty of Medicine, Alexandria, Egypt.

Background: Idiopathic intracranial hypertension (IIH) predominantly affects young, obese women and presents with signs and symptoms of increased intracranial pressure, such as headaches and visual impairment.

Objective: We aim to present our experience in the management of IIH.

Setting: University Hospital. Read More

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http://dx.doi.org/10.1016/j.soard.2020.03.032DOI Listing

Derivation of a bedside score (MASH-P) to predict 6-month mortality in tuberculous meningitis.

J Neurol Sci 2020 May 5;415:116877. Epub 2020 May 5.

Department of Neurology, King George's Medical University, U.P, Lucknow 226003, India. Electronic address:

Background: Tuberculous meningitis is commonly associated with a poor outcome. Simple bedside prognostic scores can help immensely in predicting the outcome.

Materials And Method: A total of 721 patients, from 5 of our previous studies, were included. Read More

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http://dx.doi.org/10.1016/j.jns.2020.116877DOI Listing

Transcranial Doppler for Monitoring and Evaluation of Idiopathic Intracranial Hypertension.

J Neurosci Rural Pract 2020 Apr 2;11(2):309-314. Epub 2020 May 2.

Department of Neurology, Ramaiah Medical College, Bengaluru, Karnataka, India.

 Idiopathic intracranial hypertension (IIH) is a disorder of unknown origin, characterized by features of raised intracranial pressure (ICP). Existing literature is inconclusive about the role of transcranial Doppler (TCD) in the management of IIH.  To study the TCD changes in IIH patients, pre- and post-cerebrospinal fluid (CSF) drainage. Read More

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http://dx.doi.org/10.1055/s-0040-1710086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214091PMC

Long-term Kinetic Papilledema Improvement After Venous Sinus Stenting in Idiopathic Intracranial Hypertension.

Clin Neuroradiol 2020 May 12. Epub 2020 May 12.

Department of Ophthalmology, Pitié-Salpêtrière Hospital, APHP, 47, Bd de l'Hôpital, 75013, Paris, France.

Background And Purpose: The aim of this study was to assess the safety and effectiveness of lateral sinus stenosis (LSS) stenting in patients with idiopathic intracranial hypertension (IIH) who are refractory to medical treatment, particularly focusing on visual outcomes including papilledema.

Material And Methods: Retrospective study of consecutive patients with IIH refractory to medical treatment who underwent LSS stenting. Clinical features, visual fields and optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) thicknesses were assessed before stenting, at 1 month poststenting and at last follow-up. Read More

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http://dx.doi.org/10.1007/s00062-020-00908-zDOI Listing

Posterior Globe Flattening without Papilledema in Idiopathic Intracranial Hypertension.

Neuroophthalmology 2020 Apr 19;44(2):69-70. Epub 2019 Jun 19.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.

A 64-year-old woman had a one-year history of transient visual obscurations in the left eye and was found to have left optic disc oedema with preserved visual function. She was diagnosed with unilateral papilloedema related to idiopathic intracranial hypertension. Magnetic resonance imaging of the orbits showed flattening of the globe in the right eye, which did not have disc oedema. Read More

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http://dx.doi.org/10.1080/01658107.2019.1604765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202410PMC

Central Venous Obstruction-Induced Intracranial Hypertension in Hemodialysis Patients: An Underrecognized Cause of Elevated Intracranial Pressure.

J Neuroophthalmol 2020 Jun;40(2):218-225

Departments of Neurology (DDM, SMT), Ophthalmology (DDM), Neurosurgery (DDM), and Indiana University School of Medicine, Indianapolis, Indiana.

Background: Central venous obstruction (stenosis or occlusion) is common in patients with renal failure on hemodialysis and may be associated with intracranial hypertension (IH). Causes include vein injury from an endoluminal device, lumen obstruction from a device or thrombus, external vein compression, and high venous flow leading to vein intimal hyperplasia. A combination of high venous flow and central venous obstruction can lead to intracranial venous hypertension, impaired cerebrospinal fluid (CSF) resorption, and subsequent IH. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000964DOI Listing

Imaging Methods for Differentiating Pediatric Papilledema from Pseudopapilledema: A Report by the American Academy of Ophthalmology.

Ophthalmology 2020 May 5. Epub 2020 May 5.

Stein Eye Institute, University of California, Los Angeles, California.

Purpose: To review the published literature on the accuracy of ophthalmic imaging methods to differentiate between papilledema and pseudopapilledema in children.

Methods: Literature searches were conducted in January 2020 in the PubMed database for English-language studies with no date restrictions and in the Cochrane Library database without any restrictions. The combined searches yielded 354 abstracts, of which 17 were reviewed in full text. Read More

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http://dx.doi.org/10.1016/j.ophtha.2020.03.027DOI Listing

Optic nerve sheath diameter ultrasonography for elevated intracranial pressure detection.

Ann Clin Transl Neurol 2020 May 7;7(5):865-868. Epub 2020 May 7.

Department of Neurology, The First Hospital of Jilin University, Changchun, China.

Ultrasonographically measured optic nerve sheath diameter measurement has become a common noninvasive approach for detecting elevated intracranial pressure. We present a case of aneurysmal subarachnoid hemorrhage with elevated intracranial pressure. Postoperative arachnoiditis developed, and lumbar puncture revealed low intracranial pressure. Read More

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http://dx.doi.org/10.1002/acn3.51054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261744PMC

Optic disc drusen: a systematic review : Up-to-date and future perspective.

Int Ophthalmol 2020 May 7. Epub 2020 May 7.

Department of Biomedical Science, Humanitas University, 20090, Pieve Emanuele, Milano, Italy.

Background: Optic disc drusen (ODD) are acellular deposits in the prelaminar optic nerve head. The most accredited theory is that they are secondary to abnormalities in axonal metabolism and degeneration, but the pathogenesis is not clear to date.

Clinical Manifestation: Although ODD are often considered a benign condition, the great majority of patients with ODD show visual field defects and are at higher risk for developing anterior ischemic optic neuropathy. Read More

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http://dx.doi.org/10.1007/s10792-020-01365-wDOI Listing

Influence of Optic Nerve Appearance on Visual Outcome in Pediatric Idiopathic Intracranial Hypertension.

Can J Neurol Sci 2020 May 4:1-5. Epub 2020 May 4.

Department of Ophthalmology, Emory University, Atlanta, GA, USA.

Objectives: To determine whether optic disc hemorrhages (ODH) and cotton wool spots (CWS) at presentation are associated with worse visual outcomes in pediatric patients with idiopathic intracranial hypertension (IIH).

Methods: Retrospective institutional review of 100 eyes of 50 consecutive pediatric IIH patients (aged 16 years or less) who had baseline optic disc photographs before or within 30 days of their diagnostic lumbar puncture and initiation of medical treatment. Optic disc photographs were independently graded by three ophthalmologists in a standardized manner. Read More

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http://dx.doi.org/10.1017/cjn.2020.89DOI Listing

Idiopathic Intracranial Hypertension Without Papilledema With Improvement in Visual Field Defect Following Optic Nerve Sheath Fenestration: Comment.

Authors:
Edward Margolin

J Neuroophthalmol 2020 Apr 30. Epub 2020 Apr 30.

Department of Ophthalmology and Vision Sciences and Department of Medicine, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1097/WNO.0000000000000968DOI Listing

Ocular manifestations in rheumatoid arthritis, connective tissue disease and vasculitis: a systematic review and meta-analysis.

J Rheumatol 2020 May 1. Epub 2020 May 1.

From the Schulich School of Medicine, University of Western Ontario, St. Joseph's Health Care, London, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Canadian Rheumatology Association Research studentship, University of Western Ontario. This funding was supported through the Canadian Rheumatology Association Roche summer studentship. There are no conflicts of interest. IRB was not necessary as this was a systematic literature review. Address correspondence to Dr. Janet Pope MD MPH FRCPC, Division of Rheumatology, St. Joseph's Health Care, 268 Grosvenor St. London ON N6A 4V2,

Objective: Rheumatoid Arthritis and other rheumatic diseases may present with ocular manifestations. The purpose of our work was to determine the prevalence and type of eye involvement in rheumatoid arthritis and other connective tissue diseases through a meta-analysis and literature review.

Methods: A systematic review of the literature was performed using Medline, Web of Science, and the Cochrane library from their inceptions until January 7, 2019. Read More

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http://dx.doi.org/10.3899/jrheum.190768DOI Listing

[Eye changes in space : New insights into clinical aspects, pathogenesis and prevention].

Ophthalmologe 2020 Apr 28. Epub 2020 Apr 28.

Zentrum für Augenheilkunde, Universitätsklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.

Background: More than ever research into changes in the eye caused by long-term space flight is becoming the focus of the international and national space agencies National Aeronautics and Space Administration (NASA), European Space Agency (ESA) and German Aerospace Center (DLR). In addition to space radiation-induced cataract formation considerable eye changes, summarized under space flight-associated neuro-ocular syndrome (SANS), can occur.

Objective: This article gives an overview of the current state of research and future directions in the field of research concerned with ocular alterations in SANS and presents the relevance for terrestrial ophthalmological research. Read More

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http://dx.doi.org/10.1007/s00347-020-01103-8DOI Listing

The Great Masquerader: Syphilis Mimicking Papilledema and Traction Alopecia.

Cureus 2020 Mar 24;12(3):e7391. Epub 2020 Mar 24.

Internal Medicine, John P. and Kathrine G. McGovern Medical School, University of Texas Health Science Center at Houston, Houston, USA.

Syphilis is often referred to as "the great masquerader," as it may present with a wide array of clinical symptoms and may mimic a variety of other diseases making diagnosis challenging. We report the case of a young, married woman who presented with a one-month history of significant hair loss, unintentional weight loss, blurred vision, and intermittent headaches. In addition, she endorsed positional dizziness and intermittent arthralgias. Read More

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http://dx.doi.org/10.7759/cureus.7391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179977PMC