14,706 results match your criteria Panic Disorders


Self-guided digital treatment with virtual reality for panic disorder and agoraphobia: a study protocol for a randomized controlled trial.

Trials 2022 May 21;23(1):426. Epub 2022 May 21.

Department of Clinical Psychology and Psychotherapy, University of Siegen, Obergraben 23, 57072, Siegen, Germany.

Background: Cognitive behavioral therapy is the first-line treatment for patients with panic disorder (PD) and agoraphobia (AG). Yet, many patients remain untreated due to limited treatment resources. Digital self-guided short-term treatment applications may help to overcome this issue. Read More

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Negative correlation between IL-1β, IL-12 and TNF-γ, and cortisol levels in patients with panic disorder.

Brain Behav 2022 May 19:e2624. Epub 2022 May 19.

Director of the Psychology Department, Universidad Internacional de la Rioja, Logrono, Spain.

Introduction: Chronic exposure to stress is a major risk factor in anxiety disorders (ADs) and can be accompanied by an altered microbiome-gut-brain axis and a compromised immune system. In recent years, the study of inflammatory processes in AD has gained special attention. Continued stress causes the reactivity of the hypothalamic-pituitary-adrenal (HPA) axis, the alteration of the intestinal microbiota and the consequent release of pro-inflammatory cytokines, affecting the sensitivity to stress and the similar behavior of anxiety. Read More

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Transcranial Direct Current Stimulation Does Not Improve Clinical and Neurophysiological Outcomes in Panic Disorder: A Randomized Sham-Controlled Trial.

Psychiatry Clin Neurosci 2022 May 19. Epub 2022 May 19.

Department of Psychiatry, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.

Aim: Emerging evidence suggests that transcranial Direct Current Stimulation (tDCS) has anxiolytic effects and may enhance emotional processing of threat and reduce threat-related attentional bias. Panic disorder (PD) is considered to be a fear network disorder along with prefrontal activity alterations. We aim to assess the effect of tDCS on clinical and physiological parameters in PD for the first time. Read More

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Prevalence and risk factors of mood and anxiety disorders in children and young people: Findings from the Northern Ireland Youth Wellbeing Survey.

Clin Child Psychol Psychiatry 2022 May 18:13591045221089841. Epub 2022 May 18.

Ulster University, Coleraine, Northern Ireland.

Objective: This paper presents the key findings from the Northern Ireland Youth Wellbeing Prevalence Survey (NIYWS), specifically the prevalence of common mental health disorders and their association with personal, familial and socio-economic risk factors.

Methods: The Northern Ireland Youth Wellbeing Survey (NIYWS) is a large nationally representative household survey of young people aged 2-19 years (N = 3074) and their parents (N = 2816). Data collection was by means of a stratified random probability household survey. Read More

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Beyond canvas: behavioral onset of rfc1-expansion disease in an Italian family-causal or casual?

Neurol Sci 2022 May 18. Epub 2022 May 18.

Department of Neuroscience and Rehabilitation, AziendaOspedaliera-Universitaria S. Anna, Ferrara, Italy.

Introduction: Biallelic intronic AAGGG repeat expansion in the replication factor C subunit 1 (RFC1) gene was recently identified in two/third of patients with cerebellar ataxia, sensory neuropathy, and bilateral vestibular areflexia syndrome (CANVAS). The phenotypic spectrum has expanded since (i.e. Read More

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Factor structure of the Chinese version of the Screen for Adult Anxiety Related Disorders (SCARRED).

Asian J Psychiatr 2022 May 11;73:103159. Epub 2022 May 11.

School of Public Administration, Guangzhou Xinhua University, Dongguan 523133, Guangdong Province, China.

The aim of this study was to translate and validate the Screen for Adult Anxiety Related Emotional Disorders (SCAARED). The original SCAARED was translated into Chinese and administered 6371 Chinese college students (45.4% females, mean age 18. Read More

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A Qualitative Study Exploring Management of Food Intake in the United Kingdom During the Coronavirus Pandemic.

Front Psychol 2022 27;13:869510. Epub 2022 Apr 27.

School of Psychology, Faculty of Medicine, Health and Life Science, Swansea University, Swansea, United Kingdom.

The coronavirus pandemic has impacted dietary quality through increased emotional eating and extended time spent at home, as well as instances of panic buying due to uncertainty over food availability. We recruited an opportunistic sample of 40 adults living in the United Kingdom (Female = 25; Mean age = 41.9 years) (SD = 14. Read More

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Postpartum Mood and Anxiety Disorders: A Lexicon of Metaphors.

J Holist Nurs 2022 May 16:8980101221097212. Epub 2022 May 16.

7712University of Connecticut.

Undiagnosed and untreated postpartum mental health disorders represent a silent health crisis. The aim of this paper was to develop a lexicon of metaphors women use to describe their postpartum mood and anxiety disorders to assist holistic nurses in recognizing as early as possible these struggling mothers. Mothers may not know the medical terminology to articulate their mental health problems and may turn to using metaphors. Read More

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Associations between Bruxism, Stress, and Manifestations of Temporomandibular Disorder in Young Students.

Int J Environ Res Public Health 2022 Apr 29;19(9). Epub 2022 Apr 29.

Department of Prosthetic Dentistry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.

Bruxism is a repetitive activity of the masticatory muscles, which determine teeth grinding or clenching, associated with rigidity, bracing, or thrusting of the mandibula. The aim of this study was to determine the prevalence of possible bruxism in 328 students attending the Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, and its associations with stress and other manifestations of the temporo-mandibular disorder. This was a questionnaire-based study to collect information on self-evaluation of bruxism presence, frequency of specific episodes, stress, anxiety, and other manifestations of temporo-mandibular disorder. Read More

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A multi-group confirmatory factor analysis of the revised children's anxiety and depression scale (RCADS) in Spain, Chile and Sweden.

J Affect Disord 2022 May 10;310:228-234. Epub 2022 May 10.

Department of Developmental Psychology and Didactics, University of Alicante, Carretera San Vicente del Raspeig, s/n-03690, San Vicente del Raspeig, Alicante, Spain. Electronic address:

Background: There is a need for a measure that can be used across countries and cultures to advance cross-cultural research about internalizing mental health symptoms in children and adolescents. The Revised Children's Anxiety and Depression Scale (RCADS) is a potential candidate, but no study has examined whether its scales are measured similarly in youth populations from different countries.

Methods: In this study, we use confirmatory factor analysis (CFA) and multi-group CFA to examine the cross-cultural properties of a short and free to use 30-item version of RCADS that assesses social, generalized, panic, and separation anxiety alongside depression and obsessive-compulsive symptoms. Read More

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Cannabidiol enhancement of exposure therapy in treatment refractory patients with social anxiety disorder and panic disorder with agoraphobia: A randomised controlled trial.

Eur Neuropsychopharmacol 2022 May 10;59:58-67. Epub 2022 May 10.

University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands; GGZ Drenthe, Department of Specialist Trainings, Assen, the Netherlands.

Preclinical research suggests that enhancing CB1 receptor agonism may improve fear extinction. In order to translate this knowledge into a clinical application we examined whether cannabidiol (CBD), a hydrolysis inhibitor of the endogenous CB1 receptor agonist anandamide (AEA), would enhance the effects of exposure therapy in treatment refractory patients with anxiety disorders. Patients with panic disorder with agoraphobia or social anxiety disorder were recruited for a double-blind parallel randomised controlled trial at three mental health care centres in the Netherlands. Read More

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The subfornical organ regulates acidosis-evoked fear by engaging microglial acid-sensor TDAG8 and forebrain neurocircuits in male mice.

J Neurosci Res 2022 May 12. Epub 2022 May 12.

Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, Ohio, USA.

An important role of pH homeostasis has been suggested in the physiology of panic disorder, with acidosis as an interoceptive trigger leading to fear and panic. Identification of novel mechanisms that can translate acidosis into fear will promote a better understanding of panic physiology. The current study explores a role of the subfornical organ (SFO), a blood-brain barrier compromised brain area, in translating acidosis to fear-relevant behaviors. Read More

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Repetitive transcranial magnetic stimulation for generalized anxiety and panic disorders: A systematic review and meta-analysis.

Ann Clin Psychiatry 2022 May;34(2):e2-e24

Graduate School of Biomedical Sciences, Division of Biostatistics and Epidemiology, Department of Molecular and Translational Medicine Paul L. Foster School of Medicine, Biostatistics and Epidemiology Consulting Lab, Texas Tech University Health Sciences Center, El Paso, Texas, USA.

Background: Repetitive transcranial magnetic stimulation (rTMS) is an FDA-approved, noninvasive modality for treating major depressive disorder and obsessive-compulsive disorder. Earlier studies evaluating therapeutic effects of rTMS on symptom scores of patients with generalized anxiety disorder (GAD) and panic disorder (PD) have yielded inconsistent findings.

Methods: We performed a systematic review and meta-analysis of interventional studies assessing the effect of rTMS on symptom scores in patients with GAD or PD with or without psychiatric comorbidities using studies published up to April 2021. Read More

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Pregnancy and Neonatal Outcomes After Exposure to Alprazolam in Pregnancy.

Front Pharmacol 2022 25;13:854562. Epub 2022 Apr 25.

Division of Biology and Public Health, Mokwon University, Daejeon, Korea.

Alprazolam is a commonly prescribed benzodiazepine for anxiety or panic disorder, even in pregnant women. Information on the safety of alprazolam during pregnancy is insufficient. We aimed to evaluate pregnancy and neonatal outcomes after exposure to alprazolam during pregnancy. Read More

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[Functional cardiovascular symptoms].

Dtsch Med Wochenschr 2022 Apr 11;147(10):604-612. Epub 2022 May 11.

This review provides an update on the diagnosis, differential diagnosis and management of functional cardiovascular symptoms. Typical heart-related symptoms like non-cardiac chest pain and palpitations are frequently complemented by other symptoms like dyspnea, sweating, trembling, dizziness and also further somatic symptoms like pain and fatigue. Functional cardiac symptoms are frequent, with rates of up to 30 % in chest pain units. Read More

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Cognitive-Behavioral Therapy for Panic Disorder in Patients with Stable Coronary Artery Disease: A Feasibility Study.

J Clin Psychol Med Settings 2022 May 11. Epub 2022 May 11.

School of Psychology, Université Laval, 2325 rue des Bibliothèques, Quebec, QC, G1V 0A6, Canada.

Implementing cognitive-behavioral therapy (CBT), the first-line psychological treatment for panic disorder (PD), may be challenging in patients with comorbid coronary artery disease (CAD).This study aimed at assessing the feasibility and acceptability of a CBT for PD protocol that was adapted to patients suffering from comorbid CAD. It also aimed at evaluating the efficacy of the intervention to reduce PD symptomatology and psychological distress and improve quality of life. Read More

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Eye movement desensitization and reprocessing (EMDR) and mediative behavioral therapy for the treatment of suffocation related post-traumatic stress disorder (PTSD) in amyotrophic lateral sclerosis (ALS): A case report.

Palliat Support Care 2022 May 11:1-3. Epub 2022 May 11.

Lelie Care Group, Pniël Rehabiliation Center, Rotterdam, The Netherlands.

Objective: Eye movement desensitization and reprocessing (EMDR) is an established treatment for post-traumatic stress disorders (PTSD). Some patients diagnosed with amyotrophic lateral sclerosis (ALS) experience PTSD following choking or suffocation in the course of progressive loss of the ability to breathe. Although a loss of breathing functions in ALS is relatively common, there are currently no studies available on treatment for the fear of choking following advanced ALS. Read More

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Cohort profile: intimate partner violence and mental health among women from refugee background and a comparison group of Australian-born - the WATCH cohort study.

BMJ Open 2022 May 9;12(5):e051887. Epub 2022 May 9.

Discipline of Psychiatry, School of Clinical Medicine, Faculty of Medicine, University of New South Wales, Kensington Campus, Sydney, New South Wales, Australia.

Purpose: The Women Aware with Their Children study was created because prospective data are required to accurately guide prevention programmes for intimate partner violence (IPV) and to improve the mental health and resettlement trajectories of women from refugee backgrounds in Australia.

Participants: 1335 women (685 consecutively enrolled from refugee backgrounds and 650 randomly selected Australian-born) recruited during pregnancy from three public antenatal clinics in Sydney and Melbourne, Australia. The mean age was 29. Read More

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Unsupervised clustering of autonomic temporal networks in clinically distressed and psychologically healthy individuals.

Behav Res Ther 2022 Apr 30;154:104105. Epub 2022 Apr 30.

University of California, Berkeley, USA.

The present study recruited psychologically healthy individuals and individuals with clinically-severe Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition diagnoses, including generalized anxiety disorder, major depressive disorder, social anxiety disorder, posttraumatic stress disorder, panic disorder, persistent depressive disorder, and specific phobia. During the course of a structured clinical interview, 200 individuals provided continuous electrocardiogram and impedance cardiography data. Of these N = 150 were used for exploratory analyses and N = 50 for confirmatory analyses. Read More

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Nursing Home Workers' Mental Health During the COVID-19 Pandemic in France.

J Am Med Dir Assoc 2022 Apr 7. Epub 2022 Apr 7.

Université de Bordeaux, Inserm, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.

Objectives: The present study sought to examine mental health problems among nursing home workers in the context of the COVID-19 pandemic, to investigate COVID-19-related fears, and to identify prepandemic factors associated with current mental health issues.

Design: A cross-sectional, online survey was used.

Setting And Participants: All employees among 6 nursing homes in southwestern France (N = 455) were solicited between November, 2020 and June, 2021. Read More

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How an Understanding of the Function of the Locus Coeruleus Led to Use of Dexmedetomidine to Treat Agitation in Bipolar Disorder: Example of Rational Development of Psychiatric Medications.

J Psychiatr Pract 2022 May 1;28(3):227-233. Epub 2022 May 1.

PRESKORN: Kansas University School of Medicine-Wichita, Wichita, KS.

This column reviews >50 years of research on the functions subsumed by the locus coeruleus (LC) (also called the central adrenergic system). A major role of the LC is monitoring acid-base balance in the brain and responding by regulating blood-brain permeability to water and other small molecules and cerebral blood flow. The LC, through its downward projections, also regulates and coordinates respiratory and cardiac functions. Read More

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Associations of DNA methylation of HPA axis-related genes and neuroendocrine abnormalities in panic disorder.

Psychoneuroendocrinology 2022 Apr 27;142:105777. Epub 2022 Apr 27.

Provincial Center for Mental Health, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, China; Key Laboratory of psychosomatic medicine,Chinese Academy of Medical Sciences, Chengdu 610072, China. Electronic address:

Objective: The purpose of this study was to investigate the role of aberrant DNA methylation of hypothalamic-pituitary-adrenal (HPA) axis-related genes (CRHR1, CRHR2, CRH, FKBP5, HSP90AA1, NR3C1, and POMC) in panic disorder (PD) development. We investigated the correlation among gene methylation levels, adrenocorticotropic hormone (ACTH), cortisol, and PD severity in patients.

Methods: We compared the methylation levels of HPA axis-related genes between 178 patients with PD and 184 healthy controls using MethylTarget. Read More

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The effect of mental health training on the knowledge of common mental disorders among medical officers in primary health centres in rural Karnataka.

J Family Med Prim Care 2022 Mar 10;11(3):994-999. Epub 2022 Mar 10.

Department of Psychiatry, St. John's Medical College, Bengaluru, India.

Background: Deficits in knowledge regarding identification and treatment of common mental disorders (CMD) and stigmatizing attitudes towards CMDs exist among primary care physicians in India.

Objectives: We aimed to assess the gain in knowledge of CMDs among primary health centre (PHC) doctors, after they underwent training in the identification and treatment of CMDs, and to assess the relationship between the gain in knowledge and demographic variables. We also assessed attitudes towards depression among PHC doctors who underwent training. Read More

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Panic disorder in general medical practice- A narrative review.

J Family Med Prim Care 2022 Mar 10;11(3):861-869. Epub 2022 Mar 10.

Department of Medicine (Psychiatry), College of Medicine, Shaqra University, Shaqra, KSA.

The under-or misdiagnosis, and symptomatic treatment of the panic disorder (PD), despite high prevalent medical illness, is common among non-psychiatric physicians. The non-psychiatrist physician's role is vital in the care of PD as most patients initially approach general medical settings for medical help, including primary care. However, a significant proportion is undiagnosed and undergoes either unnecessary investigation, misdiagnosed, or mismanaged even among post-Coronary Artery Bypass Grafting patients, which profoundly affects the patients functioning and quality of life. Read More

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Evaluation of olfactory bulb volume and olfactory sulcus depth in patients with panic disorder and depressive disorder: An MRI study.

Indian J Psychiatry 2022 Mar-Apr;64(2):171-177. Epub 2022 Mar 24.

Department of Ear, Nose and Throat, Bozok University School of Medicine, Yozgat, Turkey.

Background: Although some studies have shown decreases in the olfactory bulb (OB) volume and olfactory function in depressive disorder, there are no studies investigating OB volume in patients with panic disorder.

Aim: The aim of this study was to investigate whether there was a change in OB volume and olfactory sulcus (OS) depth in patients with panic and depressive disorder when compared with the control group, and which group was more affected by comparing the two disease groups.

Methods: Data of 51 patients with panic disorder and 56 patients with depressive disorder were obtained by scanning the database of the hospital retrospectively. Read More

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Prevalence and its correlates of anxiety disorders from India's National Mental Health Survey 2016.

Indian J Psychiatry 2022 Mar-Apr;64(2):138-142. Epub 2022 Mar 24.

Department of Psychiatry, Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Introduction: Anxiety disorders (ADs) impact the quality of life and productivity at an individual level and result in substantial loss of national income. Representative epidemiological studies estimating the burden of ADs are limited in India. National Mental Health Survey (NMHS) 2016 of India aimed to strengthen mental health services across India assessed the prevalence and pattern of public health priority mental disorders for mental health-care policy and implementation. Read More

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Metacognitions in Patients With Frequent Mental Disorders After Diagnosis of Pulmonary Arterial Hypertension.

Front Psychiatry 2022 14;13:812812. Epub 2022 Apr 14.

Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.

Background: The prevalence of mental disorders, particularly adjustment disorder (AD), major depressive disorder (MDD) and panic disorder (PD) is increased in patients with pulmonary arterial hypertension (PAH). However, it is unclear which pathogenic mechanisms determine their development and could therefore be targeted in prevention or therapeutic interventions. Here, we assessed metacognitions in a sample of PAH patients with and without MDD and PD. Read More

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Psychiatry Meets Cardiology: A Case Report on the Need for Mental Health Assessment in the Evaluation of Cardiovascular Symptoms.

Case Rep Psychiatry 2022 21;2022:5415196. Epub 2022 Apr 21.

Department of Psychiatry, Korle-Bu Teaching Hospital, Accra, Ghana.

Cardiovascular symptoms like chest pain and palpitations are among the commonest reasons for outpatient hospital visits. Physician preoccupation with ruling out sinister cardiological diagnoses often results in a failure to recognise mental health-related disorders, which account for over 40% of such cases, especially among young women. These disorders can independently cause cardiovascular symptoms or worsen preexisting cardiovascular disease, worsening morbidity. Read More

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