31,901 results match your criteria Pancreatitis Acute


Rare complication of milk-alkali ingestion: severe pancreatitis and acute kidney injury in a chronic hypocalcaemic patient with DiGeorge's syndrome.

BMJ Case Rep 2019 Mar 15;12(3). Epub 2019 Mar 15.

Department of Internal Medicine, St Vincent Charity Medical Center, Cleveland, Ohio, USA.

Injudicious use of over-the-counter calcium supplements has resulted in increased incidences of hypercalcaemia and related complications. We present a case of acute pancreatitis in a chronic hypocalcaemic patient of DiGeorge's syndrome. The patient came into the ED with sepsis syndrome, right upper quadrant and epigastric pain and no obvious source of infection. Read More

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http://dx.doi.org/10.1136/bcr-2018-226761DOI Listing

Elevated Circulating Levels of Motilin are Associated with Diabetes in Individuals after Acute Pancreatitis.

Exp Clin Endocrinol Diabetes 2019 Mar 14. Epub 2019 Mar 14.

School of Medicine, University of Auckland, Auckland, New Zealand.

Aim: The study aimed to investigate the associations between glycaemic control after acute pancreatitis and gastrointestinal motility, using plasma motilin concentration and gastroparesis cardinal symptom index score as proxies.

Methods: This cross-sectional study recruited a total of 93 individuals after acute pancreatitis. Gastroparesis cardinal index scores, demographic and anthropometric factors, as well as pancreatitis-related factors were analysed. Read More

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http://dx.doi.org/10.1055/a-0859-7168DOI Listing

Urinalysis and Urinary GGT-to-Urinary Creatinine Ratio in Dogs with Acute Pancreatitis.

Vet Sci 2019 Mar 13;6(1). Epub 2019 Mar 13.

Department of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, 56121 Pisa, Italy.

In acute pancreatitis (AP), kidney injury (KI) can occur. Urinalysis and some urinary biomarkers have been proposed as prognostic tools in human AP. The aim of the study was to evaluate urinalysis and urinary GGT-to-urinary creatinine (uGGT/uCr) in canine AP and their association with possible outcomes. Read More

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http://dx.doi.org/10.3390/vetsci6010027DOI Listing

[Open transgastric necrosectomy for extended walled-off pancreas necrosis].

Magy Seb 2019 Mar;72(1):8-12

Sebészeti Intézet, Debreceni Egyetem Klinikai Központ 4032 Debrecen, Móricz Zs. krt. 22.

Aims: In severe acute pancreatitis the timing of necrosectomy is ideally should be postponed 4-6 weeks after the onset of the disease when the walled-of pancreatic necrosis (WOPN) has developed. The authors present their experience with open transgastric necrosectomy for extended WOPN.

Patients And Methods: The authors performed 17 (12 male, 5 female with a mean age of 61. Read More

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http://dx.doi.org/10.1556/1046.72.2019.1.2DOI Listing

Molecular Mechanism Exploration of Pancreatitis Based on miRNA Expression Profile.

Clin Lab 2019 Mar;65(3)

Background: Pancreatitis is a popular disease around the world, and can also lead to pancreatic cancer. Pancreatitis can be distinguished into two types, acute pancreatitis (AP) and chronic pancreatitis (CP). Every year, AP leads to approximately 275,000 new cases and is the most frequent gastrointestinal disease in American. Read More

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http://dx.doi.org/10.7754/Clin.Lab.2018.180807DOI Listing

Emergency Laparoscopic Cholecystectomy: Is Dedicated Hot Gall Bladder List Cost Effective?

J Ayub Med Coll Abbottabad 2019 Jan-Mar;31(1):3-7

General Surgery, Dudley Group NHS Foundation Trust, West Midlands.

Background: Acute presentation of gall stone disease is a common emergency. Resource limitation often results in unnecessary long waiting times and repeat hospital admissions. The aim of this study was to investigate if funding a dedicated hot gall bladder list is justified. Read More

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March 2019
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Comparison of initial treatment with and without corticosteroids for suspected acute pancreatitis in dogs.

J Small Anim Pract 2019 Mar 13. Epub 2019 Mar 13.

Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Bioresource Sciences, Nihon University, Fujisawa, 252-0880, Japan.

Objectives: To compare initial treatment with and without corticosteroids for acute pancreatitis in dogs and investigate the therapeutic efficacy and prognosis.

Materials And Methods: Sixty-five dogs were included in this non-blinded, non-randomised clinical study. Dogs with acute pancreatitis received treatment either with dose of 1 mg/kg/day prednisolone (n=45) or without prednisolone (n=20). Read More

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http://dx.doi.org/10.1111/jsap.12994DOI Listing

PANCREATIC SAFETY IN STUDIES OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST ALBIGLUTIDE.

Endocr Pract 2019 Mar 13. Epub 2019 Mar 13.

Clinical Development, Alternative Development Program, GlaxoSmithKline, King of Prussia, PA.

OBJECTIVE Albiglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), reduces glycated hemoglobin (HbA) with a low risk of hypoglycemia in patients with type 2 diabetes. The relationship between GLP-1RAs and risk of pancreatitis is unresolved. This independent, rigorous, expert review of the albiglutide HARMONY Phase III clinical program examined suspected cases of acute pancreatitis. Read More

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http://dx.doi.org/10.4158/EP-2018-0507DOI Listing
March 2019
2 Reads

Extracellular RNA Profile in Mesenteric Lymph from Exemplar Rat Models of Acute and Critical Illness.

Lymphat Res Biol 2019 Mar 13. Epub 2019 Mar 13.

1 School of Biological Sciences, Faculty of Science, University of Auckland, Auckland, New Zealand.

Background: Mesenteric lymph (ML) has been implicated in the development of multiple organ dysfunction syndrome in critical illness. Extracellular RNAs play a role in cell-to-cell communication during physiological and disease processes but they are rarely studied in ML. We aimed at examining the RNA profiles of peripheral plasma, ML, and ML's extracellular vesicle (ML-EV) and triglyceride-rich lipoprotein (ML-TRL) fractions, obtained from rodent models of critical illness. Read More

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http://dx.doi.org/10.1089/lrb.2018.0044DOI Listing
March 2019
1 Read

A modified single jejunal loop reconstruction by performing proximal gastrojejunostomy after Whipple's pancreticoduodenectomy in a low-volume hospital.

Ann Hepatobiliary Pancreat Surg 2019 Feb 28;23(1):65-68. Epub 2019 Feb 28.

General Surgery Department, Batı Bahat Hospital, Istanbul, Turkey.

Backgrounds/aims: It is needed to ensure bowel and biliary tract continuity after pancreaticoduodenectomies. It is possible to find a variety of reconstruction methods in literature.

Methods: We realized a modified reconstruction method by performing proximal gastrojejunostomy, on a jejunal loop after Whipple's pancreticoduodenectomy, with surgical succes in 7 patients with pancreatic head or periampullary carcinomas in a low-volume hospital 2009-2017. Read More

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http://dx.doi.org/10.14701/ahbps.2019.23.1.65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405367PMC
February 2019

Epidemiology and disease characteristics of symptomatic choledocholithiasis in Sri Lanka.

Ann Hepatobiliary Pancreat Surg 2019 Feb 28;23(1):41-45. Epub 2019 Feb 28.

Department of Surgery, Faculty of Medical Sciences, University of Sri Jayewardenepura, Colombo, Sri Lanka.

Backgrounds/aims: Published data on choledocholithiasis in Sri Lanka is scarce. This study was conducted to determine epidemiological, clinical and endoscopic characteristics of choledocholithiasis in Sri Lanka.

Methods: This was a retrospective study of consecutive patients for a period of three years until April 2016. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.14701/ahbps.2019
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http://dx.doi.org/10.14701/ahbps.2019.23.1.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405359PMC
February 2019
1 Read

Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness cost.

World J Gastroenterol 2019 Mar;25(9):1080-1087

Department of Gastroenterology, Advocate Christ Medical Center, Oak Lawn, IL 60453, United States.

Background: Literature has suggested that imaging is over-utilized in the diagnosis of pancreatitis. If the diagnosis of acute pancreatitis (AP) is established with abdominal pain and increased serum amylase or lipase activity without systemic signs of severe disease, computed tomography (CT) imaging may not be necessary. We hypothesize that among patients with uncomplicated acute pancreatitis (AUP), there is a significant number of unwarranted CT imaging studies. Read More

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http://dx.doi.org/10.3748/wjg.v25.i9.1080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406186PMC

Dry Beriberi Due to Thiamine Deficiency Associated with Peripheral Neuropathy and Wernicke's Encephalopathy Mimicking Guillain-Barré syndrome: A Case Report and Review of the Literature.

Am J Case Rep 2019 Mar 13;20:330-334. Epub 2019 Mar 13.

Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, USA.

BACKGROUND Beriberi due to thiamine (vitamin B1) deficiency has two clinical presentations. Patients with dry beriberi present with neuropathy, and patients with wet beriberi present with heart failure, with or without neuropathy. Dry beriberi can mimic the most common form of Guillain-Barre syndrome (GBS), an acute inflammatory demyelinating polyradiculoneuropathy (AIDP). Read More

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http://dx.doi.org/10.12659/AJCR.914051DOI Listing
March 2019
2 Reads

Bone marrow-derived mesenchymal stem cells attenuate severe acute pancreatitis via regulation of microRNA-9 to inhibit necroptosis in rats.

Life Sci 2019 Mar 9. Epub 2019 Mar 9.

Department of General Surgery, Shanghai Tenth People's Hospital, Affiliated to Tongji University School of Medicine, Shanghai 200072, China. Electronic address:

Aims: Severe acute pancreatitis (SAP) is an acute disease of the digestive system accompanied by pancreatic necrosis. We have found that bone marrow-derived mesenchymal stem cells (BMSCs) can attenuate SAP, but the underlying mechanism remains unclear. The present study was conducted to explore the possible mechanisms by which BMSCs alleviate SAP. Read More

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http://dx.doi.org/10.1016/j.lfs.2019.03.019DOI Listing

c-Abl kinase regulates neutrophil extracellular trap formation, inflammation, and tissue damage in severe acute pancreatitis.

J Leukoc Biol 2019 Mar 12. Epub 2019 Mar 12.

Department of Clinical Science, Malmö, Section for Surgery, Skåne University Hospital, Lund University, Malmö, Sweden.

Neutrophil extracellular traps (NETs) are involved in acute pancreatitis (AP) but mechanisms controlling NET expulsion in AP are incompletely understood. Herein, we examined the role of c-Abelson (c-Abl) kinase in NET formation and tissue damage in severe AP. AP was induced by taurocholate infusion into pancreatic duct or intraperitoneal administration of l-arginine in mice. Read More

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http://dx.doi.org/10.1002/JLB.3A0618-222RRDOI Listing

Analysis of the Association of Administration of various glucocorticoids with development of acute pancreatitis using US Food and Drug Administration adverse event reporting system (FAERS).

J Pharm Health Care Sci 2019 28;5. Epub 2019 Feb 28.

3Department of Pharmacotherapy, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo, 204-8588 Japan.

Background: There have been debates about the association between the administration of glucocorticoids and the development of acute pancreatitis, since many anecdotal cases of this adverse event were affected either by concomitant diseases (such as systemic lupus erythematosus, SLE) that may develop acute pancreatitis without glucocorticoid treatment or by co-administered drugs with high risk for the event. The aim of the present study was to explore whether disproportionally elevated signals of developing acute pancreatitis may be detected in patients receiving glucocorticoids as compared those receiving other drugs.

Methods: We retrieved spontaneously reported cases of acute pancreatitis and clinically related adverse events (target events) from the US Food and Drug Administration Adverse Event Reporting System (FAERS) using 18 preferred terms (PTs). Read More

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http://dx.doi.org/10.1186/s40780-019-0134-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394067PMC
February 2019

Significance of radiology in the diagnosis and management of ruptured left gastric artery aneurysm associated with acute pancreatitis: Case report.

Medicine (Baltimore) 2019 Mar;98(10):e14824

Department of Radiology, The First Affiliated Hospital of Dali University, Dali, Yunnan, People's Republic of China.

Rationale: Left gastric artery aneurysms are very rare which progresses into hemorrhagic shock and diagnosis is very challenging particularly in patients with acute pancreatitis and cholecystitis whose vitals become unstable suddenly.

Patient Concerns: A 72-year-old female has presented with severe progressing abdominal pain was treated with total parenteral nutrition for acute pancreatitis based on preliminary work up, but suddenly became unstable with dropping vitals over the ensuing 48 hours. Physical examination has a positive Murphy sign and appeared lethargic. Read More

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http://dx.doi.org/10.1097/MD.0000000000014824DOI Listing

Correction to: Protective Effects of Calcitonin Gene-Related Peptide-Mediated p38 Mitogen-Activated Protein Kinase Pathway on Severe Acute Pancreatitis in Rats.

Dig Dis Sci 2019 Mar 9. Epub 2019 Mar 9.

Department of Hepatobiliary and Laparoscopic Surgery, Renmin Hospital of Wuhan University, No. 238, Jiefang Road, No. 99, Zhang Zhidong Road (Formerly Ziyang Road), Wuchang District, Wuhan, 430060, Hubei Province, People's Republic of China.

The original version of the article unfortunately contained errors in Materials and Methods section, Figure 3 and Figure 4. Read More

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http://dx.doi.org/10.1007/s10620-019-05563-0DOI Listing

Yttrium oxide nanoparticles reduce the severity of acute pancreatitis caused by cerulein hyperstimulation.

Nanomedicine 2019 Mar 6. Epub 2019 Mar 6.

Department of Regulatory Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad, Telangana, India. Electronic address:

Oxidative stress plays a major role in acute pancreatitis (AP), leading to massive macrophage infiltration. Nanoyttria (NY), possesses potent free radical scavenging activity. As reactive oxygen species and inflammation play major role in AP, we hypothesized that NY may alleviate cerulein induced AP. Read More

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http://dx.doi.org/10.1016/j.nano.2019.02.018DOI Listing

ERCP-associated infected intrahepatic pancreatic pseudocyst.

IDCases 2019 15;15:e00507. Epub 2019 Feb 15.

Department of Medicine, University of Minnesota Medical School, 420 Delaware Street SE, MMC 284, Minneapolis, MN, 55455, USA.

Introduction: Pancreatic pseudocysts are abnormal mature collections of pancreatic fluid that can develop in association with acute or chronic pancreatitis. Here, we share the discovery of an infected hepatic subcapsular pseudocyst of the pancreas causing septic shock following endoscopic retrograde cholangiopancreatography (ERCP).

Presentation Of Case: A 55-year-old woman with ethanol-related chronic pancreatitis and biliary stricture was transferred to the ICU for hypotension 8 hours following ERCP. Read More

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http://dx.doi.org/10.1016/j.idcr.2019.e00507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389541PMC
February 2019
1 Read

Assessment of acute obstructive pancreatitis by magnetic resonance imaging: Predicting the occurrence of pancreatic fistula following pancreatoduodenectomy.

Mol Clin Oncol 2019 Mar 9;10(3):371-376. Epub 2019 Jan 9.

Department of Radiology, Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.

The aim of the present study was to assess the effect of preoperative acute obstructive pancreatitis on the risk of the occurrence of pancreatic fistula (PF) following pancreaticoduodenectomy. A total of 22 patients who developed postoperative PF were carefully matched with 22 control patients without PF according to demographic data, pancreatic pathology, presenting symptoms and other surgery-associated parameters. These parameters were compared between these two groups. Read More

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http://dx.doi.org/10.3892/mco.2019.1799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388463PMC

Response to the Comment on "Outcome of Acute Pancreatic and Peripancreatic Collections Occurring in Patients With Acute Pancreatitis".

Ann Surg 2019 Apr;269(4):e52-e53

Postgraduate Institute of Medical Education and Research, Chandigarh, India Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1097/SLA.0000000000002912DOI Listing

Comment on "Outcome of Acute Pancreatic and Peripancreatic Collections Occurring in Patients With Acute Pancreatitis".

Authors:
Edward L Bradley

Ann Surg 2019 Apr;269(4):e51-e52

Department of Surgery, Florida State University College of Medicine, Tallahassee, FL.

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http://dx.doi.org/10.1097/SLA.0000000000002854DOI Listing

Qingyi Decoction amerliorates acute biliary pancreatitis by targeting Gpbar1/NF-kb pathway.

Front Biosci (Landmark Ed) 2019 Mar 1;24:833-848. Epub 2019 Mar 1.

General Surgery Department, the First Affiliated Hospital of Dalian Medical University, Zhongshan Road 222#, Xigang district, Dalian 116011, China.

Acute biliary pancreatitis (ABP) is a potentially life-threatening disease that is induced by the common bile duct (CBD) sludge or stones. This study aimed to investigate protective effects of Qingyi Decoction (QYT) on deoxycholic-acid-sodium salt (DCA) induced ABP in rats. Gpbar1 is a G-protein coupled receptor that can be activated by DCA. Read More

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Hypertriglyceridemia: An Infrequent, Difficult-to-Predict, Severe Metabolic and Vascular Problem Associated with Estrogen Administration.

Authors:
Thomas F Whayne

Curr Vasc Pharmacol 2019 Mar 5. Epub 2019 Mar 5.

Gill Heart and Vascular Institute University of Kentucky Lexington, Kentucky. United States.

Supplementary estrogen plays important roles for female patients as convenient birth control, relief of postmenopausal symptoms, and in management of other selected problems. However, as is the case for essentially all medications, there are side effects. Short of a major pulmonary embolus, the most severe side effect of estrogen would appear to be sporadic, rare, and severe hypertriglyceridemia associated with acute pancreatitis. Read More

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http://dx.doi.org/10.2174/1570161117666190306102322DOI Listing
March 2019
1 Read

Endotherapy for pancreatic necrosis: An update.

JGH Open 2019 Feb 7;3(1):80-88. Epub 2018 Dec 7.

Department of Pediatrics Indira Gandhi Institute of Medical Sciences Patna India.

Approximately 20% of patients with acute pancreatitis develop pancreatic necrosis. The presence of necrosis in a pancreatic collection significantly worsens the prognosis. Pancreatic necrosis is associated with high mortality and morbidity. Read More

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http://dx.doi.org/10.1002/jgh3.12109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386747PMC
February 2019

Thoracic complications of pancreatitis.

JGH Open 2019 Feb 22;3(1):71-79. Epub 2018 Oct 22.

Department of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh India.

Acute pancreatitis in its severe form may lead to systemic inflammatory response syndrome and multisystem organ dysfunction. Acute lung injury is an important cause of mortality in the setting of severe acute pancreatitis. Besides lung involvement, acute and chronic pancreatitis may also lead to the involvement of other thoracic compartments, including mediastinum, pleura, and vascular structures. Read More

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http://dx.doi.org/10.1002/jgh3.12099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386740PMC
February 2019
1 Read

Formation of Pancreatoduodenal Fistula in Intraductal Papillary Mucinous Neoplasm of the Pancreas Decreased the Frequency of Recurrent Pancreatitis.

Gastroenterology Res 2019 Feb 26;12(1):43-47. Epub 2019 Feb 26.

Saint Louis University School of Medicine, St. Louis, MO, USA.

Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are characterized by proliferation of mucin-secreting cells in the main pancreatic duct (PD) or its branches. The secreted thick mucin usually leads to PD obstruction and dilation. A common complication of IPMN is recurrent acute pancreatitis secondary to poor pancreatic fluid drainage, and rarely, pancreatobiliary and pancreatointestinal fistulae. Read More

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http://dx.doi.org/10.14740/gr1140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396797PMC
February 2019
1 Read

Coxsackie B2 Virus Infection Causing Multiorgan Failure and Cardiogenic Shock in a 42-Year-Old Man.

Tex Heart Inst J 2019 02 1;46(1):32-35. Epub 2019 Feb 1.

Infections from coxsackie B2 viruses often cause viral myocarditis and, only rarely, multisystem organ impairment. We present the unusual case of a 42-year-old man in whom coxsackie B2 virus infection caused multiorgan infection, necessitating distal pancreatectomy, splenectomy, renal dialysis, and venoarterial extracorporeal membrane oxygenation with mechanical ventilation. In addition, the patient had a rapid-eye-movement sleep-related conduction abnormality that caused frequent sinus pauses of longer than 10 s, presumably due to myocarditis from the coxsackievirus infection. Read More

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http://dx.doi.org/10.14503/THIJ-17-6361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378994PMC
February 2019
1 Read

Establishing a model to measure and predict the quality of gastrointestinal endoscopy.

World J Gastroenterol 2019 Feb;25(8):1024-1030

Digestive Endoscopy Center, Department of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai 200433, China.

Background: Tens of millions of gastrointestinal endoscopic procedures are performed every year in China, but the quality varies significantly and related factors are complex. Individual endoscopist- and endoscopy division-related factors may be useful to establish a model to measure and predict the quality of endoscopy.

Aim: To establish a model to measure and predict the quality of gastrointestinal endoscopic procedures in mainland China. Read More

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https://www.wjgnet.com/1007-9327/full/v25/i8/1024.htm
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http://dx.doi.org/10.3748/wjg.v25.i8.1024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397728PMC
February 2019
1 Read

Chemerin alleviates acute pancreatitis in the rat thorough modulation of NF-κB signal.

Pancreatology 2019 Feb 11. Epub 2019 Feb 11.

Department of Medical Physiology Faculty of Health Sciences, Krakow, Poland.

Objective: Chemerin, an adipokine, works as the chemoattractant for the immune cells. The role of chemerin in the inflammatory reaction is controversial. Chemerin has been shown to aggravate the inflammatory response, but other studies demonstrated its anti-inflammatory influence. Read More

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http://dx.doi.org/10.1016/j.pan.2019.02.005DOI Listing
February 2019
1 Read

[FASCIOTOMY IN THE COMPLEX TREATMENT OF THE ABDOMINAL COMPARTMENT SYNDROME FOR PANCREATIC NECROSIS].

Georgian Med News 2019 Jan(286):40-45

Tbilisi State Medical University, Department of Surgery №1; The First University clinic TSMU; N. Kipshidze Central Clinic, Tbilisi, Georgia.

The long-term history of studying of a problem of acute pancreatitis in its different aspects, is fight against a pancreatic necrosis and a pancreatic infection. Technology progress in improvement of diagnostic methods and treatment of a pancreatic necrosis and its complications, changed a situation, but treatment of such patients remains the most difficult task for the doctors dealing with pancreatitis issues. The main factor of risk at a pancreatic necrosis are: gland necrosis volume, the severity of enzymatic endo intoxication, degree of intraabdominal hypertension, a translocation of microbes from intestines in the blood circulation and an abdominal cavity. Read More

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January 2019
3 Reads

Acute Pancreatitis as a Complication of Intragastric Balloons: a Case Series.

Obes Surg 2019 Mar 2. Epub 2019 Mar 2.

Department of Medicine, Division of Gastroenterology, King Khalid University Hospital, King Saud University, P.O. Box 2925(59), Riyadh, 11461, Saudi Arabia.

Intragastric balloon (IGB) placement for the treatment of obesity has been in use for more than three decades. The major advantage of IGBs is that they preserve the anatomy of the stomach and are generally considered safe; the most common complications are nausea/vomiting and abdominal pain, and very rarely are IGBs associated with mortality (0.05%). Read More

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http://dx.doi.org/10.1007/s11695-019-03796-6DOI Listing
March 2019
1 Read

Current management of acute idiopathic pancreatitis and acute recurrent pancreatitis.

Rev Clin Esp 2019 Feb 27. Epub 2019 Feb 27.

Servicio de Gastroenterología y Hepatología, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, España.

Acute pancreatitis is an entity of notable importance due to its high incidence and its non-negligible morbidity and mortality. Idiopathic acute pancreatitis is that in which the cause of the clinical condition cannot be determined after an initial basic study. Understanding the underlying aetiology enables clinicians to propose a targeted treatment to reduce the risk of recurrence. Read More

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http://dx.doi.org/10.1016/j.rce.2018.12.011DOI Listing
February 2019

Seizure as the Presenting Symptom for Atypical Hemolytic Uremic Syndrome.

J Emerg Med 2019 Feb 27. Epub 2019 Feb 27.

Geisel School of Medicine at Dartmouth, Hanover, New Hampshire and Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire.

Background: Atypical hemolytic uremic syndrome (aHUS) is a complement-mediated disease manifesting in thrombocytopenia, microangiopathic hemolytic anemia, and acute kidney injury. It has a higher incidence of extrarenal manifestations, including central nervous system findings like seizure or stroke, pancreatitis, and cardiac manifestations.

Case Report: We present a case of an unimmunized 14-month-old girl presenting with generalized seizure and ultimately diagnosed with aHUS. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07364679183122
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http://dx.doi.org/10.1016/j.jemermed.2018.12.034DOI Listing
February 2019
2 Reads

Hypercalcemia secondary to excessive self-medication with antacids causing acute pancreatitis: a case report.

Croat Med J 2019 Feb;60(1):42-45

Pietro Vassallo, Department of Surgery, Royal United Hospitals Bath NHS Foundation Trust, Combe Park, Bath, BA1 3NG, United Kingdom,

Excessive self-medication with over-the-counter drugs is an issue commonly encountered by health care professionals. It can result in uncommon presentations of life-threatening illnesses. These medications are frequently overlooked by clinicians when taking histories from patients, and their risks are often downplayed. Read More

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February 2019
2 Reads

The Relationship between Liver Injury and Serum Levels of C-Reactive Protein and Procalcitonin in Patients with Acute Pancreatitis.

J Coll Physicians Surg Pak 2019 Mar;29(3):287-289

The Emergency Area of First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China.

Acute pancreatitis (AP) can cause damage to multiple organs in the whole body, and the liver is one of the most frequently affected by AP. Ninety-six AP patients, consisting 67 patients with liver injury, were enrolled. They were classified as mild AP (MAP) and severe AP (SAP), according to the Atlanta Revised Classification, with 50 healthy subjects serving as the controls. Read More

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http://dx.doi.org/10.29271/jcpsp.2019.03.287DOI Listing
March 2019
1 Read

Pegaspargase-induced hypertriglyceridemia in a patient with acute lymphoblastic leukemia.

J Oncol Pharm Pract 2019 Mar 1:1078155219833438. Epub 2019 Mar 1.

3 Division of Blood and Marrow Transplantation, Department of Medicine, University of California San Diego, La Jolla, CA, USA.

Pegaspargase, a long acting formulation of L-asparaginase, is an asparagine specific enzyme that selectively kills leukemic cells by depleting plasma asparagine. Pegaspargase is FDA approved for the first-line treatment of adult acute lymphoblastic leukemia and is a critical component of numerous multi-chemotherapeutic regimens. Pegaspargase is associated with well-described toxicities including hypersensitivity reactions, hepatotoxicity, and thrombosis. Read More

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http://dx.doi.org/10.1177/1078155219833438DOI Listing
March 2019
1 Read

Inflammatory process of patients receiving parenteral nutrition is not exclusively responsible for low selenium and glutathione peroxidase levels.

Nutrition 2018 Oct 26;61:202-207. Epub 2018 Oct 26.

College of Medical Sciences, State University of Campinas (UNICAMP), Campinas, SP, Brazil; São Leopoldo Mandic College of Medicine and Dentistry, Campinas, SP, Brazil.

Objective: The aim of this study was to verify if the selenium status of patients residing in locations with selenium-poor soil who receive parenteral nutrition (PN) without selenium supplementation is associated with the inflammatory process.

Methods: This was a prospective cohort study with hospitalized patients who started PN. The analyzed biochemical tests were plasma selenium, glutathione peroxidase (GPx), C-reactive protein, prealbumin, albumin, creatinine, lymphocytes, total cholesterol, high-density lipoprotein, and triglycerides. Read More

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http://dx.doi.org/10.1016/j.nut.2018.09.034DOI Listing
October 2018
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Acute pancreatitis and acute kidney injury in dogs.

Vet J 2019 Mar 17;245:77-81. Epub 2019 Jan 17.

Veterinary Teaching Hospital 'Mario Modenato', Department of Veterinary Sciences, University of Pisa, Via Livornese Lato monte, San Piero a Grado 56122, Pisa, Italy.

Acute pancreatitis and acute kidney injury are well-documented comorbidities in human medicine. Dogs that develop acute kidney injury during hospitalization have significantly higher mortality rates than those that do not. The aim of this study was to evaluate the prevalence of acute kidney injury in dogs with acute pancreatitis and the prognostic value of various clinicopathological parameters. Read More

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http://dx.doi.org/10.1016/j.tvjl.2019.01.002DOI Listing
March 2019
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Elevated red cell distribution width to platelet count ratio predicts poor prognosis in patients with breast cancer.

Sci Rep 2019 Feb 28;9(1):3033. Epub 2019 Feb 28.

Department of Thoracic and Breast Surgery, Oita University Faculty of Medicine, Oita, 879-5593, Japan.

Red cell distribution width (RDW) to platelet ratio (RPR) is a prognosticator in acute pancreatitis and myocardial infarction; however, the prognostic values of RDW and RPR in breast cancer have not been studied. This retrospective analysis of 299 breast cancer patients investigated the association between RDW and RPR and clinicopathological characteristics and prognosis, compared to platelet distribution width to platelet count ratio (PDW/P) which is a known independent prognostic factor in patients with breast cancer. We found a significant correlation between RPR, and age and HER2 status. Read More

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http://dx.doi.org/10.1038/s41598-019-40024-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395769PMC
February 2019
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Ileal Tuberculosis Causing Hypercalcemia and Renal Failure.

Indian J Nephrol 2019 Jan-Feb;29(1):53-56

Department of Nephrology, Aster Medcity, Kochi, Kerala, India.

Hypercalcemia rarely causes acute pancreatitis due to secretory block in the pancreas and damage by accumulated proteases. Hypercalcemia, though described in granulomatous disorders, is uncommon in tuberculosis. Acute kidney injury is known to occur with acute pancreatitis, secondary to sepsis and septic shock; however, acute pancreatitis resulting in acute cortical necrosis is very rare. Read More

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http://dx.doi.org/10.4103/ijn.IJN_426_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375019PMC
March 2019
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Functional Abdominal Pain in a Pediatric Patient After Resolution of Acute Pancreatitis: A Case Report.

A A Pract 2019 Feb 21. Epub 2019 Feb 21.

From the Departments of Anesthesiology and Critical Care Medicine and.

Children with acute pancreatitis may develop chronic abdominal wall pain after resolution of clinical, laboratory, and radiographic signs of disease. We describe a 13-year-old boy who underwent an unrevealing, complex diagnostic evaluation for persistent abdominal pain after resolution of acute pancreatitis. His pain required an extended leave of absence from school and nasogastric tube feeds. Read More

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http://dx.doi.org/10.1213/XAA.0000000000000980DOI Listing
February 2019
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The consensus of integrative diagnosis and treatment of acute pancreatitis-2017.

J Evid Based Med 2019 Feb;12(1):76-88

Digestive Disease Committee, Chinese Association of Integrative Medicine.

Acute pancreatitis (AP) is one of the most common acute abdominal diseases. The digestive disease committee, Chinese Association of Integrative Medicine, released Integrated traditional Chinese and Western medicine for diagnosis and treatment of acute pancreatitis in 2010. Since then, further studies and great progress have been made by domestic and foreign counterparts from the perspective of both Chinese and Western medicine in AP, including the classification, fluid resuscitation, organ function maintenance, surgery intervention, enteral nutrition (EN), and syndrome differentiation and treatment. Read More

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http://dx.doi.org/10.1111/jebm.12342DOI Listing
February 2019
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[Treatment of acute necrotizing pancreatitis].

Internist (Berl) 2019 Mar;60(3):226-234

Medizinische Klinik und Poliklinik II, Universitätsklinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Deutschland.

Acute pancreatitis (AP) has an annual incidence of 30-45 per 100,000 inhabitants. In Germany approximately one third of the cases are of biliary or alcoholic origin. The diagnosis is based on the typical epigastric pain with radiation and a threefold increase of lipase or amylase in serum. Read More

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http://dx.doi.org/10.1007/s00108-019-0558-yDOI Listing
March 2019
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Etiology and clinical characteristics of pediatric acute pancreatitis in Saudi Arabia: a 20-year experience from a single tertiary center.

Int J Pediatr Adolesc Med 2018 Mar 24;5(1):13-17. Epub 2018 Feb 24.

King Abdullah Specialist Children Hospital, Pediatric Gastroenterology, Riyadh, Saudi Arabia.

Background: Cases of acute pancreatitis (AP) have increased among pediatric populations worldwide; however, the natural course of this condition in Saudi Arabia was unknown.

Aim: To report the characteristics as well as outcomes of pediatric AP.

Patients And Methods: A retrospective chart review study was conducted to include acute pancreatitis in patients ≤ 19 years. Read More

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http://dx.doi.org/10.1016/j.ijpam.2018.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363251PMC
March 2018
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Nonalcoholic Fatty Liver Disease Aggravated the Severity of Acute Pancreatitis in Patients.

Biomed Res Int 2019 22;2019:9583790. Epub 2019 Jan 22.

Department of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou University, No. 386 Hanjiang Media Road, Yangzhou 225000, Jiangsu, China.

Background And Aim: The incidence of nonalcoholic fatty liver disease (NAFLD) as a metabolic disease is increasing annually. In the present study, we aimed to explore the influence of NAFLD on the severity of acute pancreatitis (AP).

Methods: The severity of AP was diagnosed and analyzed according to the 2012 revised Atlanta Classification. Read More

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https://www.hindawi.com/journals/bmri/2019/9583790/
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http://dx.doi.org/10.1155/2019/9583790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362474PMC
January 2019
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"Endoscopic ultrasound first policy" in acute pancreatitis of presumed biliary origin.

Authors:
Vincent Zimmer

Am J Med 2019 Feb 22. Epub 2019 Feb 22.

Department of Medicine, Marienhausklinik St. Josef Kohlhof, Neunkirchen, Germany; Department of Medicine II, Saarland University Medical Center, Saarland University Homburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2019.01.033DOI Listing
February 2019