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Clin Case Rep 2022 Jun 19;10(6):e5971. Epub 2022 Jun 19.

Department of Dermatology Hedi Chaker Hospital Sfax Tunisia.

Panniculitis has various etiologies. One of the less common causes is trauma and hence traumatic fat necrosis (FN). These soft tissue injuries usually appear on the shins, thighs, breasts, arms, and buttocks. Read More

Food Res Int 2022 Jul 19;157:111386. Epub 2022 May 19.

College of Food Science, Southwest University, Chongqing 400715, People's Republic of China; Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing, Chongqing 400715, People's Republic of China. Electronic address:

Type 2 diabetes is a serious threat to human health. Tartary buckwheat bran dietary fiber has good hypoglycemic activity, with its modification widely studied. However, the hypoglycemic activity of steam explosion modified Tartary buckwheat bran soluble dietary fiber (SE-SDF) has not been reported. Read More

Am J Case Rep 2022 Jun 27;23:e936255. Epub 2022 Jun 27.

Department of General Surgery, Venizeleio General Hospital of Heraklion, Heraklion, Crete, Greece.

BACKGROUND Biloma is the collection of bile outside the biliary tree as a result of visceral perforation. The most common site of disruption is the gallbladder, whereas common bile duct lesions usually occur following medical procedures or trauma. Spontaneous perforation of the common bile duct has been previously reported in the literature. Read More

Exp Ther Med 2022 Jul 26;24(1):468. Epub 2022 May 26.

Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong 518033, P.R. China.

Systemic injury plays a central role in severe acute pancreatitis (SAP). Retrograde biliopancreatic duct infusion of sodium taurocholate (NaT) is commonly used to establish SAP animal models. To better characterize the systemic injury in this model, SAP was induced in Sprague-Dawley rats by NaT administration (3. Read More

World J Gastrointest Surg 2022 May;14(5):521-524

Department of Surgery, University of Cape Town Health Sciences Faculty, Cape Town 7925, South Africa.

We comment on a study titled "Feasibility and safety of "bridging" pancreaticogastrostomy for pancreatic trauma in Landrace pigs" in which ten pigs were randomized to either experimental "bridging" pancreaticogastrostomy (PG) or a control group with a routine mucosa-to-mucosa PG. At six months anastomoses had strictured and closed in both groups. The authors concluded that "bridging" PG is feasible and safe in damage control surgery during the early stage of pancreatic injury. Read More

World J Gastroenterol 2022 May;28(20):2243-2247

Gastroenterology and Endoscopy Unit, Ospedale G. Mazzini, Teramo 64100, Italy.

Background: Intramural duodenal hematoma is a rare condition described for the first time in 1838. This condition is usually associated with blunt abdominal trauma in children. Other non-traumatic risk factors for spontaneous duodenal haematoma include several pancreatic diseases, coagulation disorders, malignancy, collagenosis, peptic ulcers, vasculitis and upper endoscopy procedures. Read More

Front Endocrinol (Lausanne) 2022 3;13:818252. Epub 2022 Jun 3.

Pediatric Academic Clinical Programme, Lee Kong Chian School of Medicine, Singapore, Singapore.

Recurrent and profound hypoglycemia is a leading cause of neonatal brain injury. Small-for-gestational-age infants are at risk of hypoglycemia due to substrate deficiency and hyperinsulinism. Inappropriate insulin secretion by the β-cells of the pancreas results in hypoglycemia, neuronal energy deprivation, and parieto-occipital brain injury. Read More

Exp Ther Med 2022 Jul 18;24(1):452. Epub 2022 May 18.

Department of Hepatobiliary and Pancreatic Surgery, Kanghua Hospital, Dongguan, Guangdong 523080, P.R. China.

Laparoscopic pancreaticoduodenectomy is one of the most challenging operations in abdominal surgery, with a high risk and numerous potential complications. Laparoscopy can magnify the surgical field, improving vision, but it cannot see through and identify the internal structures of the surgical field. Intraoperative navigation is a technology currently being developed; it projects the three-dimensional (3D) image established before surgery onto the surgical area during surgery, locates the anatomical landmarks, matches the 3D image with the actual image, and then displays the relationship between the tumor and the surrounding blood vessels. Read More

World J Gastrointest Endosc 2022 May;14(5):342-350

Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD 21201, United States.

Background: In order to successfully manage traumatic pancreatic duct (PD) leaks, early diagnosis and operative management is paramount in reducing morbidity and mortality. In the acute setting, endoscopic retrograde cholangiopancreatography (ERCP) can be a useful, adjunctive modality during exploratory laparotomy. ERCP with sphincterotomy and stent placement improves preferential drainage in the setting of injury, allowing the pancreatic leak to properly heal. Read More

Front Public Health 2022 27;10:866376. Epub 2022 May 27.

Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, China.

Acute organophosphorus pesticide poisoning (AOPP) with cardiac arrest has an extremely high mortality rate, and corresponding therapeutic strategies have rarely been reported. Therefore, this study aimed to explore the prognostic factors and effective treatments of AOPP-related cardiac arrest. This retrospective study was conducted in our department in the years 2018-2021. Read More

Mater Today Bio 2022 Jun 6;15:100276. Epub 2022 May 6.

Department of Clinical Laboratory Medicine, Southwest Hospital, Army Medical University, 30 Gaotanyan, Shapingba District, Chongqing, 400038, China.

The synchronous detection and regulation of microRNAs (miRNAs) are essential for the early tumor diagnosis and treatment but remains a challenge. An integrative DNA tetrahedral nanomachine was self-assembled for sensitive detection and negative feedback regulation of intracellular miRNAs. This nanomachine comprised a DNA tetrahedron nanostructure as the framework, and a miRNA inhibitor-controlled allosteric DNAzyme as the core. Read More

Cureus 2022 May 6;14(5):e24793. Epub 2022 May 6.

Surgical Gastroenterology, Government Mohan Kumaramangalam Medical College Hospital, Salem, IND.

Introduction Pancreatic trauma is rare and is usually associated with adjacent organ and vascular injuries, which adds to the high morbidity and mortality. In the American Association for the Surgery of Trauma (AAST) pancreatic trauma (PT) grading system, the higher grades are a composite of less and more severe extents of injuries. We hereby present an observational study of PT with management based on an indigenous algorithmic approach. Read More

ANZ J Surg 2022 Jun 8. Epub 2022 Jun 8.

Discipline of Surgery, The University of Adelaide, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

Background: One-third of Australia's population reside in rural and remote areas. This audit aims to describe all-causes of mortality in rural general surgical patients, and identify areas of improvement.

Methods: This is a retrospective multi-centre study involving four South Australian hospitals (Mt Gambier, Whyalla, Port Augusta, and Port Lincoln). Read More

Curr Med (Cham) 2022 26;1(1). Epub 2022 May 26.

Department of Otolaryngology and Head Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730 China.

Objective: The pandemic of 2019 coronavirus (SARS-CoV-2) disease (COVID-19) has imposed a severe public health burden worldwide. Most patients with COVID-19 were mild. Severe patients progressed rapidly to critical condition including acute respiratory distress syndrome (ARDS), multi-organ failure and even death. Read More

Gastroenterology 2022 Jun 4. Epub 2022 Jun 4.

Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Prz Gastroenterol 2022 1;17(2):103-109. Epub 2021 Oct 1.

Department of General Surgery, Paterno' Biancavilla Hospital, Paternò Biancavilla, Italy.

Diagnosis of pancreatic cancer is challenging in the initial phases because its progression is rapid. The pancreatic tail and body roughly accounts for 20-30% of all cancerous cases. The standard treatment for symptomatic benign, malignant, and premalignant diseases of the pancreatic tail and body is distal pancreatectomy. Read More

Radiol Case Rep 2022 Aug 29;17(8):2668-2672. Epub 2022 May 29.

Gastroenterology Unit, Azienda Ospedaliera, Via Migliori 1, Cosenza 87100, Italy.

Visceral arterial pseudoaneurysms are uncommon vascular abnormalities affecting renal or splanchnic arteries. They can be complications of chronic pancreatitis, blunt or penetrating abdominal trauma, or surgical, endoscopic and interventional radiological procedures. Visceral arterial pseudoaneurysms can be life-threatening because of hemorrhagic shock secondary to rupture and massive bleeding. Read More

World J Clin Cases 2022 May;10(14):4535-4540

Department of Hepatobiliary Surgery, Hebei General Hospital, Shijiazhuang 050000, Hebei Province, China.

Background: Regular abdominal massage can be used to treat digestive symptoms such as bloating and constipation and is reported to reduce abdominal discomfort, improve digestive function, and increase the quality of life, without serious adverse effects. Isolated pancreatic injury is rare, and most often occurs during severe trauma such as steering wheel impact injury. To our knowledge, pancreatic injury caused by massage has not yet been reported in the literature. Read More

J Vet Emerg Crit Care (San Antonio) 2022 Jun 1. Epub 2022 Jun 1.

Animal Medical Center, New York, New York, USA.

Objective: To review the current literature pertaining to the pathophysiology, diagnosis, and treatment of injuries sustained from high-rise syndrome in cats and dogs.

Etiology: High-rise syndrome is defined as a fall from a height of 2 or more stories that results in a constellation of injuries, including thoracic, abdominal, orthopedic, and orofacial trauma. Animals often fall after slipping from windowsills, engaging in mating behavior, or chasing prey. Read More

BMJ Case Rep 2022 Jun 1;15(6). Epub 2022 Jun 1.

Gastroenterology and Hepatology, UPMC, Pittsburgh, Pennsylvania, USA.

Immunoglobulin G4-related disease (IgG4-RD) is a rare fibroinflammatory immune-mediated condition which can affect multiple organ systems and form mass-like lesions. Initial presentation can mimic other diseases such as pancreatic malignancy when there is pancreatic involvement or tuberculosis (TB) when there are pulmonary lesions or hypertrophic pachymeningitis (HP). Here, we report a novel case of IgG4-RD presenting as bilateral subdural haematomas with additional findings. Read More

Life (Basel) 2022 May 6;12(5). Epub 2022 May 6.

General, Emergency and Transplant Surgery Department, ASST-Settelaghi and University of Insubria, 21100 Varese, Italy.

Liver involvement after abdominal blunt trauma must be expected, and in up to 30% of cases, spleen, kidney, and pancreas injuries may coexist. Whenever hemodynamics conditions do not contraindicate the overcoming of the ancient dogma according to which exploratory laparotomy should be performed after every major abdominal trauma, a CT scan has to clarify the liver lesions so as to determine the optimal management strategy. Except for complete vascular avulsion, no liver trauma grade precludes nonoperative management. Read More

Life (Basel) 2022 Apr 21;12(5). Epub 2022 Apr 21.

Department of Thermophysiology, Institute for Translational Medicine, Medical School, University of Pécs, 12 Szigeti Street, H7624 Pécs, Hungary.

Background: Paediatric second-degree burn injuries are a significant source of medical challenges to the population that may cause severe, lifelong complications. Currently, there are dozens of therapeutic modalities and we aimed to summarise their reported outcomes and determine their effectiveness, compared to the widely used silver sulphadiazine (SSD).

Methods: We conducted the meta-analysis and systematic review of randomised controlled trials (RCTs), which investigated the performance of dressings in acute paediatric partial-thickness burns. Read More

J Clin Med 2022 May 20;11(10). Epub 2022 May 20.

Surgery Department, "Iuliu Haţieganu" University of Medicine and Pharmacy, Street Emil Isac no 13, 400023 Cluj-Napoca, Romania.

(1) Background: Emergency pancreatoduodenectomy (EPD) is a rare procedure, especially in non-trauma centers. Pancreatoduodenectomy is a challenging intervention, that has even higher risks in emergency settings. However, EPD can be a life-saving procedure in selected cases. Read More

Biomedicines 2022 May 2;10(5). Epub 2022 May 2.

Department of Gastrointestinal Surgery, Medical University of Silesia in Katowice, ul. Medyków 14, 40-752 Katowice, Poland.

(1) Background: The choice of appropriate surgical suture during operation is of great significance. Currently, there are no objective studies regarding the resistance of commonly used sutures in biliary tract surgery. (2) Methods: This fact leads one to conduct research concerning the resistance of the sutures (Polydioxanone, Poliglecaprone, Poliglactin 910, and their analogues coated with antibacterial triclosan) in the environment of sterile and contaminated bile and pancreatic juice. Read More

Front Immunol 2022 6;13:823511. Epub 2022 May 6.

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Neutrophil extracellular traps (NETs) play important roles in hepatic ischemic reperfusion injury (IRI) and acute rejection (AR)-induced immune responses to inflammation. After liver transplantation, HMGB1, an inflammatory mediator, contributes to the development of AR. Even though studies have found that HMGB1 can promote NET formation, the correlation between NETs and HMGB1 in the development of AR following liver transplantation has not been elucidated. Read More

Ann Med Surg (Lond) 2022 Jun 13;78:103564. Epub 2022 Apr 13.

Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.

Background: Pancreatic trauma occurs in 0.2-2% of patients with blunt trauma and 1-12% of patients with penetrating trauma. The mortality and morbidity rates range from 9 to 34% and 30-60% respectively. Read More

J Trauma Acute Care Surg 2022 May 18. Epub 2022 May 18.

Department of Surgery, University of Cape Town Health Sciences Faculty, Trauma Centre, Groote Schuur Hospital, Cape Town, South Africa.

J Trauma Acute Care Surg 2022 May 18. Epub 2022 May 18.

University of Colorado, Denver, Colorado, USA.

Br J Surg 2022 May 16. Epub 2022 May 16.

Department of General, Visceral, Cancer and Transplantation Surgery, University Hospital of Cologne, Cologne, Germany.

Background: Recent findings support the hypothesis of sex-related differences in inflammatory and immunological responses to trauma. The aim of this study was to address sex-specific aspects in patients who underwent pancreatic surgery.

Methods: This retrospective study used data from the German StuDoQ registry. Read More

MedComm (2020) 2022 Jun 6;3(2):e132. Epub 2022 May 6.

National Translational Science Center for Molecular Medicine&Department of Cell Biology State Key Laboratory of Cancer Biology the Fourth Military Medical University Xi'an P.R. China.

Systemic inflammatory response syndrome (SIRS) is characterized by dysregulated cytokine release, immune responses and is associated with organ dysfunction. IL-6R blockade indicates promising therapeutic effects in cytokine release storm but still remains unknown in SIRS. To address the issue, we generated the human knock-in mice and a defined epitope murine anti-human membrane-bound IL-6R (mIL-6R) mAb named h-mIL-6R mAb. Read More