6,443 results match your criteria Pancreatic Trauma


Acute Pancreatitis after Colonoscopy: A Case Presentation and Literature Review.

Case Rep Gastrointest Med 2019 15;2019:4587371. Epub 2019 Jan 15.

Division of Gastroenterology, Department of Medicine, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, PA, USA.

We report a case of acute pancreatitis after an elective screening colonoscopy. A 51-year-old male with a left ventricular assist device for end-stage nonischemic cardiomyopathy and a family history of colorectal cancer was admitted for an expedited heart transplant evaluation. He underwent screening colonoscopy during this admission which was technically uncomplicated apart from requiring slight maneuvering at the splenic flexure. Read More

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http://dx.doi.org/10.1155/2019/4587371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350525PMC
January 2019

Endoscopic Retrograde Cholangiopancreatography in Pediatric Populations.

Curr Treat Options Gastroenterol 2019 Feb 12. Epub 2019 Feb 12.

Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1007/s11938-019-00225-6DOI Listing
February 2019

Unusual duplication and vulnerable intrapancreatic course of the left gastroepiploic artery: a rare anatomical variation.

Surg Radiol Anat 2019 Feb 5. Epub 2019 Feb 5.

Department of Anatomy, Melaka Manipal Medical College (Manipal Campus), Manipal Academy of Higher Education, Manipal, India.

The left gastroepiploic artery (LGEA) is the least described artery in the medical literature. Unusual variations of this artery might lead to vascular injuries, causing intraoperative bleeding after surgery. We observed rare vascular variations in an adult male cadaver. Read More

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http://dx.doi.org/10.1007/s00276-019-02188-wDOI Listing
February 2019

Visceral Injuries in Patients with Blunt and Penetrating Abdominal Trauma Presenting to a Tertiary Care Facility in Karachi, Pakistan.

Cureus 2018 Nov 17;10(11):e3604. Epub 2018 Nov 17.

General Surgery, Jinnah Postgraduate Medical College, Karachi, PAK.

Introduction Abdominal injuries are responsible for 10% of the mortalities due to trauma. Delays in early diagnosis or misdiagnoses are two major reasons for the mortality and morbidity associated with abdominal trauma. The objectives of this study were to determine the frequency of visceral injuries in patients with abdominal trauma and compare the frequency of visceral injuries in patients with blunt and penetrating abdominal trauma. Read More

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http://dx.doi.org/10.7759/cureus.3604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338406PMC
November 2018

A case of perforation of a pancreatic duct by a pancreatic stent during chemoradiotherapy for pancreatic head cancer: a case report.

Surg Case Rep 2019 Jan 23;5(1):10. Epub 2019 Jan 23.

Department of Surgical Oncology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.

Background: Pancreatic injuries are rare, and no treatment plan has yet been established for grade III injuries. In many cases, pancreatic stent placement has resulted in saving patients. However, some cases of perforation of a pancreatic duct during the placement of a stent have been described, and there are also a few cases of delayed perforation by a pancreatic stent. Read More

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https://surgicalcasereports.springeropen.com/articles/10.118
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http://dx.doi.org/10.1186/s40792-019-0571-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346691PMC
January 2019
11 Reads

Portal vein pseudoaneurysm secondary to pancreatic lymphoma and biliary stent insertion: a rare cause of haemobilia.

CVIR Endovasc 2018 28;1(1). Epub 2018 Jun 28.

2University College London Hospital, Euston Road, London, NW1 2BU UK.

Background: Haemobilia, defined as bleeding from the biliary tree, is a rare entity. The most common cause of haemobilia is iatrogenic trauma, which accounts for 70% of cases. Pseudoaneurysms of the portal vein are an extremely rare cause of haemobilia with only four reported cases to date. Read More

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http://dx.doi.org/10.1186/s42155-018-0011-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319504PMC
June 2018
1 Read

Biomechanical Stability and Osteogenesis in a Tibial Bone Defect Treated by Autologous Ovine Cord Blood Cells-A Pilot Study.

Molecules 2019 Jan 15;24(2). Epub 2019 Jan 15.

Department of Orthopedics and Trauma Surgery, University of Duisburg-Essen, 45147 Essen, Germany.

The aim of this study was to elucidate the impact of autologous umbilical cord blood cells (USSC) on bone regeneration and biomechanical stability in an ovine tibial bone defect. Ovine USSC were harvested and characterized. After 12 months, full-size 2. Read More

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http://dx.doi.org/10.3390/molecules24020295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358876PMC
January 2019
4 Reads

Percutaneous Endoscopic Gastrostomy Tube Insertion-induced Superior Mesenteric Artery Injury Treated with Angiography.

Korean J Gastroenterol 2018 Dec;72(6):308-312

Division of Gastroenterology, Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.

Percutaneous endoscopic gastrostomy (PEG) is widely used to provide nutritional support for patients with dysphagia and/or disturbed consciousness preventing oral ingestion, and PEG tube placement is a relatively safe and convenient non-surgical procedure performed under local anesthesia. However, the prevention of PEG-insertion-related complications is important. A 64-year-old man with recurrent pneumonia underwent tracheostomy and nasogastric tube placement for nutritional support and opted for PEG tube insertion for long-term nutrition. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.4166/kjg.2018.72
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http://dx.doi.org/10.4166/kjg.2018.72.6.308DOI Listing
December 2018
4 Reads

Extra-Hepatic Bile Duct Injury in Blunt Trauma; A Systematic Review.

J Trauma Acute Care Surg 2019 Jan 8. Epub 2019 Jan 8.

Hepatobiliary and Pancreatic Surgery Unit, Level 4, The Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, 4102, QLD.

Background: Extra-hepatic bile duct injuries (EHBDIs) are a rare consequence of blunt abdominal trauma. The purpose of this study was to establish mechanisms of injury, clinical indicators of EHBDI following blunt trauma (both with investigative modalities and intraoperatively), method and timing of injury detection, and definitive treatment options.

Method: A Systematic Review was performed to gather data on patients with an extrahepatic bile duct injury secondary to blunt trauma. Read More

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http://dx.doi.org/10.1097/TA.0000000000002186DOI Listing
January 2019
2 Reads

4-Phenylbutyric Acid Attenuates Endoplasmic Reticulum Stress-Mediated Intestinal Epithelial Cell Apoptosis in Rats with Severe Acute Pancreatitis.

Dig Dis Sci 2019 Jan 4. Epub 2019 Jan 4.

Department of General Surgery, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, 430060, Hubei province, China.

Objectives: The present study aimed to determine whether intestinal epithelial cell (IECs) apoptosis could be induced by endoplasmic reticulum stress (ERS) in severe acute pancreatitis (SAP), and the role of chemical chaperone 4-phenylbutyric acid (4-PBA) in SAP-associated intestinal barrier injury.

Methods: Twenty-four male Sprague Dawley rats were randomly divided into three groups: the sham operation group, the SAP group, and the SAP model plus 4-PBA treatment group (4-PBA group). A rat model of SAP was induced by retrograde injection of 5% sodium taurocholate (STC) into the biliopancreatic duct; in the 4-PBA group, 4-PBA was injected intraperitoneally at a dose of 50 mg/kg body weight for 3 days before modeling. Read More

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http://dx.doi.org/10.1007/s10620-018-5437-1DOI Listing
January 2019
4 Reads
2.550 Impact Factor

Aberrant splenic artery rising from the superior mesenteric artery: a rare but important anatomical variation.

Surg Radiol Anat 2019 Jan 3. Epub 2019 Jan 3.

General, Digestive, and Endocrine Surgery, Nouvel Hôpital Civil, Université de Strasbourg, 1 Place de L'hôpital, 67100, Strasbourg, France.

Aberrant splenic artery originating from the superior mesenteric artery (SMA) is extremely rare and recognition of this anomaly is important in the pre-operative planning of complex surgery such as pancreatic surgery, liver transplantation and vascular surgery. We present the case of an 80-year-old female diagnosed as septic shock due to mesenteric ischemia and obstructive pyelonephritis. Her splenic artery was originating from the SMA and the anomaly was readily appreciated on the pre-operative CT images. Read More

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http://dx.doi.org/10.1007/s00276-018-02177-5DOI Listing
January 2019
5 Reads

Mesenchymal chondrosarcoma metastasising to the pancreas.

BMJ Case Rep 2018 Dec 31;11(1). Epub 2018 Dec 31.

General Surgery, Helios Klinikum Berlin-Buch, Berlin, Germany.

The mesenchymal chondrosarcoma (MC) is a rare malignant tumour and accounts for less than 3% of primary chondrosarcomas. Mostly MC arises from the craniofacial bones, the ribs, the ilium, the femur and the vertebrae. A 54-year-old man was treated due to an icterus of unknown origin. Read More

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http://dx.doi.org/10.1136/bcr-2018-226369DOI Listing
December 2018
3 Reads

Antioxidant and Hypoglycemic Effects of Acidic-Extractable Polysaccharides from on Type 2 Diabetes Mice.

Oxid Med Cell Longev 2018 25;2018:9150807. Epub 2018 Nov 25.

College of Life Science, Shandong Agricultural University, Tai'an 271018, China.

The present work was performed to evaluate the effect of acidic-extractable polysaccharides (AE-PS) from fruit bodies of on type 2 diabetes mellitus (T2DM) and its structural characteristics. The T2DM mice induced by high-fat diet (HFD) and streptozotocin (STZ) were administered with 100 and 400 mg/kg AE-PS for 4 weeks. Our work proved that AE-PS decreased the levels of serum lipid, lipid peroxidation, and blood glucose; improved glucose and insulin resistance; enhanced antioxidant enzyme activities; and attenuated the injuries of the liver, kidney, and pancreas in T2DM mice. Read More

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https://www.hindawi.com/journals/omcl/2018/9150807/
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http://dx.doi.org/10.1155/2018/9150807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286747PMC
February 2019
7 Reads

The streptozotocin-high fat diet induced diabetic mouse model exhibits severe skin damage and alterations in local lipid mediators.

Biomed J 2018 Oct 3;41(5):328-332. Epub 2018 Nov 3.

Faculty of Biological Sciences, Department of Physiology, Pontifical Catholic University of Chile, Santiago, Chile.

Background: Type 2 diabetes (T2D) can go undiagnosed for years, leading to a stage where produces complications such as delayed skin wound healing. Animal models have been developed in the last decades to study the pathological progression in this disease. Streptozotocin (STZ), that has a selective pharmacological toxicity toward pancreatic β cells, in addition to high fat diet has been widely used to induce diabetes however no evidence has shown its effects on the skin integrity. Read More

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http://dx.doi.org/10.1016/j.bj.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306302PMC
October 2018
2 Reads

Gastrointestinal Bleeding Secondary to Iliac Artery Pseudoaneurysm in a Patient With Remote Pancreas Transplant: A Case Report.

Transplant Proc 2018 Dec 29;50(10):4087-4089. Epub 2018 May 29.

Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN. Electronic address:

Background: Vascular complications represent the most common cause of early graft failure after pancreatic transplantation (PT). Pseudoaneurysms are uncommon vascular complications that usually present within the first year post transplantation.

Case Report: A 49-year-old man with history of type 1 diabetes mellitus presented for evaluation with a 2-day history of painless hematochezia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00411345183072
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http://dx.doi.org/10.1016/j.transproceed.2018.05.015DOI Listing
December 2018
11 Reads

Rupture of the common bile duct due to blunt trauma, presenting difficulty in diagnosis.

BMJ Case Rep 2018 Dec 10;11(1). Epub 2018 Dec 10.

Surgery, JCHO Chukyo Hospital, Nagoya, Japan.

Rupture of the common bile duct because of blunt trauma is extremely rare. Preoperative diagnosis is very difficult because bile causes little peritoneal irritation. We present a case of a 19-year-old young woman with rupture of the common bile duct due to blunt trauma. Read More

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http://www.bmj.com/lookup/doi/10.1136/bcr-2018-226467
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http://dx.doi.org/10.1136/bcr-2018-226467DOI Listing
December 2018
2 Reads

Clinical outcomes of primary arterial embolization in severe hepatic trauma: A systematic review.

Diagn Interv Imaging 2019 Feb 13;100(2):65-75. Epub 2018 Dec 13.

General, Emergency and Robotic Surgery Unit, San Francesco Hospital, 08100 Nuoro NU, Italy.

Purpose: This purpose of this systematic review was to determine the safety and efficacy of arterial embolization as the primary treatment for grade III-V liver trauma, excluding the postoperative use of arterial embolization.

Material And Methods: A total of 24 studies published between January 2000 and June 2018 qualified for inclusion in this study. Four of them were prospective studies and 20 were retrospective. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22115684183024
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http://dx.doi.org/10.1016/j.diii.2018.10.004DOI Listing
February 2019
5 Reads

Quest for the optimal technique of laparoscopic splenectomy - vessels first or hilar transection?

Wideochir Inne Tech Maloinwazyjne 2018 Dec 30;13(4):460-468. Epub 2018 May 30.

2 Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland.

Introduction: Throughout our 20 years of experience, we have used several different techniques for laparoscopic splenectomy (LS). However, two methods have been used most frequently: "vessels first" and "hilar transection".

Aim: To evaluate the outcomes of LS performed with these two different approaches. Read More

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https://www.termedia.pl/doi/10.5114/wiitm.2018.76071
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http://dx.doi.org/10.5114/wiitm.2018.76071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280088PMC
December 2018
8 Reads

"Management of Duodenal Trauma: A Retrospective Review From The Pan-American Trauma Society'.

J Trauma Acute Care Surg 2018 Dec 6. Epub 2018 Dec 6.

Shock Trauma Centre, University of Maryland.

Introduction: The operative management of duodenal trauma remains controversial. Our hypothesis is that a simplified operative approach could lead to better outcomes.

Methods: We conducted an international multicenter study, involving thirteen centers. Read More

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http://dx.doi.org/10.1097/TA.0000000000002157DOI Listing
December 2018
1 Read

Elaboration of a thermosensitive smart biomaterial: From synthesis to the ex vivo bioadhesion evaluation.

Colloids Surf B Biointerfaces 2019 Mar 30;175:91-97. Epub 2018 Nov 30.

CIRIMAT, Université de Toulouse 3 - Paul Sabatier, CNRS, Toulouse, France. Electronic address:

Alginate and chitosan are polysaccharides that are widely used in the biomedical field, especially as wound dressings. Controlled bioadhesion is an advanced functionality that offers the potential to reduce injuries due to the stripping-off of the biomaterial. Herein, we report the efficient grafting of poly-N(isopropylacryamide) (PNIPAM), a thermosensitive polymer that exhibits a lower critical solution temperature (LCST) at 32 °C on the alginate/chitosan polyelectrolyte complex (PEC) surface. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2018.11.084DOI Listing
March 2019
3 Reads

Gut microbiota dysbiosis worsens the severity of acute pancreatitis in patients and mice.

J Gastroenterol 2018 Dec 5. Epub 2018 Dec 5.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, 17 Yong Waizheng Street, Donghu District, Nanchang, 330006, Jiangxi, China.

Background: The gut is implicated in the pathogenesis of acute pancreatitis (AP) and the infectious complications of AP are commonly associated with enteric bacteria, yet whether gut microbiota dysbiosis participants in AP severity remains largely unknown.

Methods: We collected clinical information and fecal samples from 165 adult participants, including 41 with mild AP (MAP), 59 with moderately severe AP (MSAP), 30 with severe AP (SAP) and 35 healthy controls (HC). The serum inflammatory cytokines and gut barrier indexes were detected. Read More

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http://dx.doi.org/10.1007/s00535-018-1529-0DOI Listing
December 2018
4 Reads

Reducing the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis using 4-Fr pancreatic plastic stents placed with common-type guidewires: Results from a prospective multinational registry.

Dig Endosc 2018 Dec 1. Epub 2018 Dec 1.

Methodist Dallas Medical Center, Dallas, USA.

Background And Aim: Pancreatic plastic stents (PPS) can reduce the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP). Prospective multicenter documentation of PEP rate after PPS placement is scarce. A new 4-Fr stent designed to be deployed over a 0. Read More

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http://doi.wiley.com/10.1111/den.13311
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http://dx.doi.org/10.1111/den.13311DOI Listing
December 2018
7 Reads

External validation of a clinical prediction rule for very low risk pediatric blunt abdominal trauma.

Am J Emerg Med 2018 Nov 23. Epub 2018 Nov 23.

Department of Pediatrics, Division of Pediatric Emergency Medicine, Vanderbilt University Medical Center, 2200 Children's Way Suite 1025, Nashville, TN 37232, USA. Electronic address:

Background: Computed tomography (CT) is frequently used to identify intra-abdominal injuries in children with blunt abdominal trauma (BAT). The Pediatric Emergency Care Applied Research Network (PECARN) proposed a prediction rule to identify children with BAT who are at very low risk for clinically-important intra-abdominal injuries (CIIAI) in whom CT can be avoided.

Objective: To determine the sensitivity of this prediction rule in identifying patients at very low risk for CIIAI in our pediatric trauma registry. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07356757183094
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http://dx.doi.org/10.1016/j.ajem.2018.11.031DOI Listing
November 2018
8 Reads

International publication trends in hepato-pancreato-biliary surgery: emergency compared to oncology.

ANZ J Surg 2018 Dec 4. Epub 2018 Dec 4.

Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.

Background: There is growing interest in publishing trends given the increasing amount of research publication across various specialities. Studies relating to hepato-pancreato-biliary (HPB) surgery show an oncological focus compared to benign, emergency and trauma.

Methods: Analysis of ISI JCR impact factors in the Web of Knowledge and the Scimago Journal Rank through Scopus was performed to select four readily available, relevant and frequently read journals from the surgery category. Read More

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http://doi.wiley.com/10.1111/ans.14962
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http://dx.doi.org/10.1111/ans.14962DOI Listing
December 2018
6 Reads

Spleen-preserving spleen-sacrificing distal pancreatectomy in adults with blunt major pancreatic injury.

BJS Open 2018 Dec 10;2(6):426-432. Epub 2018 Jul 10.

Department of General Surgery, Chang Gung Memorial Hospital Chang Gung University Tao-Yuan City Taiwan.

Background: The aim of this study was to analyse outcomes of spleen-preserving (SPDP) and spleen-sacrificing (SSDP) distal pancreatectomy in adults with severe blunt pancreatic injuries.

Methods: This was an observational study of adult patients who underwent distal pancreatectomy for grade III or IV blunt pancreatic injury between 1991 and 2015. Outcomes of SPDP and SSDP were compared. Read More

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http://dx.doi.org/10.1002/bjs5.89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253790PMC
December 2018
2 Reads

Volumetric decrease of pancreas after abdominal irradiation, it is time to consider pancreas as an organ at risk for radiotherapy planning.

Radiat Oncol 2018 Dec 3;13(1):238. Epub 2018 Dec 3.

Department of Radiation Oncology, Dr. Lutfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey.

Background: Volumetric shrinkage of normal tissues such as salivary glands, kidneys, hippocampus are observed after radiotherapy. We aimed to assess the alterations in pancreatic volume of patients who received abdominal radiotherapy and define pancreas as an organ at risk for radiation treatment planning.

Material-methods: Forty-nine patients operated for gastric adenocarcinoma who received adjuvant abdominal radiotherapy were in the study group, 27 patients with early stage disease who did not need adjuvant treatment after surgery comprised the control group. Read More

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http://dx.doi.org/10.1186/s13014-018-1189-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276196PMC
December 2018
3 Reads

Development of an acute pancreatitis porcine model based on endoscopic retrograde infusion of contrast medium or sodium taurocholate.

Korean J Intern Med 2018 Nov 16. Epub 2018 Nov 16.

Digestive Disease Center, Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea.

Background/aims: A reproducible, endoscope-based, large animal model, of acute pancreatitis was developed to meet the need for a suitable means of preclinically testing treatments. The aim of this study was to develop an endoscope-based animal model of acute pancreatitis.

Methods: This experimental study was conducted on six mini-pigs. Read More

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http://kjim.org/journal/view.php?doi=10.3904/kjim.2017.367
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http://dx.doi.org/10.3904/kjim.2017.367DOI Listing
November 2018
11 Reads

Variability in the evalution of pediatric blunt abdominal trauma.

Pediatr Surg Int 2018 Nov 13. Epub 2018 Nov 13.

Medical University of South Carolina, Charleston, SC, USA.

Purpose: To describe the practice pattern for routine laboratory and imaging assessment of children following blunt abdominal trauma (BAT).

Methods: Children (age < 16 years) presenting to 14 pediatric trauma centers following BAT over a 1-year period were prospectively identified. Injury, demographic, routine laboratory and imaging utilization data were collected. Read More

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http://link.springer.com/10.1007/s00383-018-4417-z
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http://dx.doi.org/10.1007/s00383-018-4417-zDOI Listing
November 2018
19 Reads

In trauma, expect the unexpected: a rare case of post-traumatic pancreatitis associated with salmonellosis and enterocolitis.

BMJ Case Rep 2018 Nov 8;2018. Epub 2018 Nov 8.

Department of Pediatric Surgery, Children's Health Children's Medical Center Dallas, Dallas, Texas, USA.

A 16-year-old Hispanic man was transferred to our level I paediatric trauma centre with pancreatitis. Ten days prior, he had sustained a gunshot wound to the abdomen requiring an exploratory laparotomy for repair of a traumatic left diaphragmatic injury. Additional injuries included gastric, renal, liver and pancreatic lacerations as well as a T12 burst fracture that resulted in paraplegia. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22628
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http://dx.doi.org/10.1136/bcr-2018-226286DOI Listing
November 2018
4 Reads

Niacin Pretreatment Attenuates Ischemia and Reperfusion of Pancreas-induced Acute Pancreatitis and Remote Lung Injury Through Suppressing Oxidative Stress and Inflammation and Activation of SIRT1.

Authors:
T-H Chen J-J Wang

Transplant Proc 2018 Nov 15;50(9):2860-2863. Epub 2018 Mar 15.

School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan. Electronic address:

Background: Lung injury subsequent to pancreatic ischemia and reperfusion (PIR) due to shock, revascularization, and pancreas transplantation is a major clinical problem. In addition to proteases, massive production and release of reactive oxygen species (ROS) and induction of inflammatory cytokines have been implicated in remote lung injury. Niacin, also known as vitamin B, is both antioxidative and anti-inflammatory. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00411345183038
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http://dx.doi.org/10.1016/j.transproceed.2018.03.052DOI Listing
November 2018
11 Reads

Biliary Complications During and After Donor Hepatectomy in Living Donor Liver Transplantation Focusing on Characteristics of Biliary Leakage and Treatment for Intraoperative Bile Duct Injury.

Transplant Proc 2018 Nov 15;50(9):2705-2710. Epub 2018 Mar 15.

Department of Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Japan.

Background: Biliary complication is one of the major donor complications during and after hepatectomy in living donor liver transplantation (LDLT). We evaluated risk factors for donor biliary complication in adult-to-adult LDLT.

Patients And Methods: From March 2002 to November 2016, 126 consecutive patients who underwent donor hepatectomy in adult-to-adult LDLT were divided into 2 groups according to biliary compilations: nonbiliary complication (non-BC) group (n = 114) and biliary complication (BC) group (n = 12). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00411345183037
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http://dx.doi.org/10.1016/j.transproceed.2018.03.045DOI Listing
November 2018
5 Reads

Magnesium isoglycyrrhizinate alleviates liver injury in obese rats with acute necrotizing pancreatitis.

Pathol Res Pract 2019 Jan 28;215(1):106-114. Epub 2018 Oct 28.

Dept of General Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China. Electronic address:

Objective: For patients with acute necrotizing pancreatitis (ANP), a high body mass index (BMI) increases the likelihood of acute hepatic injury (AHI). In the current study, we explored whether magnesium isoglycyrrhizinate (MgIg) could alleviate ANP-induced liver injury in obese rats.

Methods: Sprague-Dawley (SD) rats were selected for the present study, and the ANP model was established by retrograde injection of 5% sodium taurocholate into the biliary-pancreatic duct. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03440338183093
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http://dx.doi.org/10.1016/j.prp.2018.10.030DOI Listing
January 2019
11 Reads

Dexamethasone-induced inhibition of miR-132 via methylation promotes TGF-β-driven progression of pancreatic cancer.

Int J Oncol 2019 Jan 1;54(1):53-64. Epub 2018 Nov 1.

Molecular Oncosurgery, Section of Surgical Research, University of Heidelberg, 69120 Heidelberg, Germany.

Glucocorticoids (GCs) such as dexamethasone (DEX) are administered as cancer co‑treatment for palliative purposes due to their pro‑apoptotic effects in lymphoid cancer and limited side effects associated with cancer growth and chemotherapy. However, there is emerging evidence that GCs induce therapy resistance in most epithelial tumors. Our recent data reveal that DEX promotes the progression of pancreatic ductal adenocarcinoma (PDA). Read More

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http://www.spandidos-publications.com/10.3892/ijo.2018.4616
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http://dx.doi.org/10.3892/ijo.2018.4616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255064PMC
January 2019
4 Reads

Indications and outcomes of duodenum-preserving resection of the pancreatic head in children.

Pediatr Surg Int 2018 Nov 1. Epub 2018 Nov 1.

Department of Surgery, University Hospital Kralovske Vinohrady, Prague, Czech Republic.

Aim Of Study: Duodenum-preserving resection of the pancreatic head (DPRPH) with Roux-en-Y pancreatojejunostomy is a procedure used to remove focal pathological lesions of the pancreatic head. Although predominantly used in adult patients, it is both safe and effective in children. The aim of this study was to review our experience with this procedure, with focus on its indications, complications and long-term outcomes. Read More

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http://link.springer.com/10.1007/s00383-018-4410-6
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http://dx.doi.org/10.1007/s00383-018-4410-6DOI Listing
November 2018
10 Reads

Methods for Monitoring Macroautophagy in Pancreatic Cancer Cells.

Methods Mol Biol 2019 ;1882:197-206

Laboratory of Molecular Pathology and Nanobioimaging, Department of Health Sciences, Università del Piemonte Orientale, Novara, Italy.

Macroautophagy is a catabolic process through which redundant, aged, or damaged cellular structures are first enclosed within double-membrane vesicles (called autophagosomes), and thereafter degraded within lysosomes. Macroautophagy provides a primary route for the turnover of macromolecules, membranes and organelles, and as such plays a major role in cell homeostasis. As part of the stress response, autophagy is crucial to determine the cell fate in response to extracellular or intracellular injuries. Read More

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http://dx.doi.org/10.1007/978-1-4939-8879-2_18DOI Listing
January 2019
2 Reads

Dual-Incision Laparoscopic Spleen-Preserving Distal Pancreatectomy: Merits Compared to the Conventional Method.

J Gastrointest Surg 2018 Oct 26. Epub 2018 Oct 26.

Department of Hepato-biliary and Pancreas Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.

Background: Herein, we assess the safety and feasibility of dual-incision laparoscopic spleen-preserving distal pancreatectomy (DILSPDP) through lateral approach with reduced trocars for benign and low-grade malignancy in pancreas tail. We compare DILSPDP with surgical outcomes of conventional laparoscopic spleen-preserving distal pancreatectomy (LSPDP).

Methods: Patients with benign pancreas tail mass that had been scheduled for LSPDP were selected to undergo DILSPDP. Read More

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http://link.springer.com/10.1007/s11605-018-4013-5
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http://dx.doi.org/10.1007/s11605-018-4013-5DOI Listing
October 2018
5 Reads

Overproduction of Tenascin-C Driven by Lipid Accumulation in the Liver Aggravates Hepatic Ischemia/Reperfusion Injury in Steatotic Mice.

Liver Transpl 2019 Feb;25(2):288-301

The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA.

The purpose of this study was to assess the significance of tenascin-C (Tnc) expression in steatotic liver ischemia/reperfusion injury (IRI). The critical shortage in donor organs has led to the use of steatotic livers in transplantation regardless of their elevated susceptibility to hepatic IRI. Tnc is an endogenous danger signal extracellular matrix molecule involved in various aspects of immunity and tissue injury. Read More

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http://doi.wiley.com/10.1002/lt.25365
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http://dx.doi.org/10.1002/lt.25365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355355PMC
February 2019
11 Reads

Surgical Margin Status of Patients with Pancreatic Ductal Adenocarcinoma Undergoing Surgery with Radical Intent: Risk Factors for the Survival Impact of Positive Margins.

In Vivo 2018 Nov-Dec;32(6):1591-1597

Division of General Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R.O.C.

Background: For pancreatic ductal adenocarcinoma (PDAC), surgical margin status is an important pathological factor for evaluating surgical adequacy. In this study, we attempted to investigate predictive factors for the survival impact of positive surgical margins.

Materials And Methods: From February 2004 to December 2013, 204 patients were diagnosed with PDAC and underwent surgery with radical intent; 189 patients fulfilled our selection criteria and were enrolled for analysis. Read More

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http://iv.iiarjournals.org/lookup/doi/10.21873/invivo.11419
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http://dx.doi.org/10.21873/invivo.11419DOI Listing
January 2019
2 Reads

Development and validation of a prognostic model for kidney function 1 year after combined pancreas and kidney transplantation using pre-transplant donor and recipient variables.

Langenbecks Arch Surg 2018 Nov 18;403(7):837-849. Epub 2018 Oct 18.

Core Facility Quality Management Transplantation, Integrated Research and Treatment Center Transplantation (IFB-Tx), Hannover Medical School, Hannover, Germany.

Purpose: The widening gap between demand and supply of organs for transplantation provides extraordinary challenges for ethical donor organ allocation rules. The transplant community is forced to define favorable recipient/donor combinations for simultaneous kidney-pancreas transplantation. The aim of this study is the development of a prognostic model for the prediction of kidney function 1 year after simultaneous pancreas and kidney transplantation using pre-transplant donor and recipient variables with subsequent internal and external validation. Read More

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http://dx.doi.org/10.1007/s00423-018-1712-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244698PMC
November 2018
2 Reads

Acute pancreatitis in children: A single center experience over ten years.

Turk J Pediatr 2018 ;60(2):153-158

Departments of Pediatric Gastroenterology, Hepatology and Nutrition, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey.

Sağ E, Kaya G, Bahat-Özdoğan E, Karahan SC, İmamoğlu M, Sarıhan H, Çakır M. Acute pancreatitis in children: A single center experience over ten years. Turk J Pediatr 2018; 60: 153-158. Read More

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http://www.turkishjournalpediatrics.org/doi.php?doi=10.24953
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http://dx.doi.org/10.24953/turkjped.2018.02.006DOI Listing
January 2018
13 Reads

A retrospective study of 157 hospitalized cats with pancreatitis in a tertiary care center: Clinical, imaging and laboratory findings, potential prognostic markers and outcome.

J Vet Intern Med 2018 Nov 13;32(6):1874-1885. Epub 2018 Oct 13.

Department of Small Animal Internal Medicine, Koret School of Veterinary Medicine - Veterinary Teaching Hospital and Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel.

Background: Pancreatitis in cats (FP) has been increasingly diagnosed in recent years, but clinical studies of large numbers of affected cats are scarce.

Objectives: To describe a large cohort of cats with FP requiring hospitalization.

Animals: One hundred and fifty-seven client-owned cats. Read More

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http://doi.wiley.com/10.1111/jvim.15317
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http://dx.doi.org/10.1111/jvim.15317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271303PMC
November 2018
8 Reads

Focal change of the pancreatic texture using a direct injection mixture of N-butyl cyanoacrylate and lipiodol in the pig model: a strategy for preventing pancreatic leakage during pancreatic surgery.

Ann Surg Treat Res 2018 Oct 28;95(4):175-182. Epub 2018 Sep 28.

Department of Hepato-Biliary and Pancreas Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Purpose: A soft texture of the pancreas is one of the most important predisposing factors for a pancreatic fistula. Thus, in a porcine model, we investigated a method to harden the pancreas locally by directly injecting an artificial material.

Methods: During the laparotomy, 51 samples from 17 pigs, including 13 survival models, were randomly divided into 3 groups and either received a direct injection into the pancreas of MHL (1:4 mixture of histoacryl [n-butyl cyanoacrylate] and lipiodol) (group E) or saline (group C) or only received a pinprick into the pancreas without injecting a substance (sham). Read More

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https://synapse.koreamed.org/DOIx.php?id=10.4174/astr.2018.9
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http://dx.doi.org/10.4174/astr.2018.95.4.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172351PMC
October 2018
2 Reads

Variations in the branching pattern of the celiac trunk and its clinical significance.

Authors:
Hemamalini

Anat Cell Biol 2018 Sep 28;51(3):143-149. Epub 2018 Sep 28.

Department of Anatomy, Jagadguru Sri Shivarathreeshwara Medical College, Mysore, India.

Celiac trunk is the artery of foregut, arising from the abdominal aorta at the level of T12/L1 vertebral body. It extends approximately 1.5 to 2 cm horizontally forwards before dividing into three branches: left gastric, common hepatic, and splenic arteries. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.5115/acb.2018.51
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http://dx.doi.org/10.5115/acb.2018.51.3.143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172596PMC
September 2018
3 Reads

[Technique of invaginative pancreatojejunostomy in pancreatectomy].

Khirurgiia (Mosk) 2018 (9):31-35

Chair of Hospital-Based Surgery, Pavlov Ryazan State Medical University of Healthcare Ministry of Russia, Ryazan, Russia.

Pancreatoenterostomy is one of the key moments in pancreatic surgery. It was proposed invaginative pancreatojejunostomy in end-to-side fashion by using of two continuous single-row purse-string sutures. This technique may be used in pancreatoduodenectomy and Beger's procedure. Read More

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http://dx.doi.org/10.17116/hirurgia2018090131DOI Listing
January 2018

Reimaging in pediatric blunt spleen and liver injury.

J Pediatr Surg 2018 Sep 16. Epub 2018 Sep 16.

Children's Mercy Hospital, 4201 Gilham Rd, Kansas City, MO, USA, 64108.

Background: APSA guidelines do not recommend routine reimaging for pediatric blunt liver or spleen injury (BLSI). This study characterizes the symptoms, reimaging, and outcomes associated with a selective reimaging strategy for pediatric BLSI patients.

Methods: A planned secondary analysis of reimaging in a 3-year multi-site prospective study of BLSI patients was completed. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.08.060DOI Listing
September 2018
27 Reads

Evaluation of Circulating MicroRNA Biomarkers in the Acute Pancreatic Injury Dog Model.

Int J Mol Sci 2018 Oct 6;19(10). Epub 2018 Oct 6.

Department of Pathology, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.

This study aimed to evaluate the usefulness of four microRNAs (miRNAs) in an acute pancreatic injury dog model. Acute pancreatitis was induced by infusion of cerulein for 2 h (7.5 μg/kg/h). Read More

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http://www.mdpi.com/1422-0067/19/10/3048
Publisher Site
http://dx.doi.org/10.3390/ijms19103048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212914PMC
October 2018
4 Reads
2.862 Impact Factor

Normal pancreatic volume in adults is influenced by visceral fat, vertebral body width and age.

Abdom Radiol (NY) 2018 Oct 8. Epub 2018 Oct 8.

Department of Radiology, Aalborg University Hospital, Aalborg, Denmark.

Objectives: The aim was to describe the pancreatic volume (PV) in a cohort of subjects with no prior history of pancreatic disease, and to explore the relationship between PV and conventional two-point measurements of the pancreas. Associations between PV, gender, age, abdominal body composition, and human height were explored as well.

Methods: CT scans from 204 trauma patients (20-80 years, 100 males) were evaluated. Read More

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http://dx.doi.org/10.1007/s00261-018-1793-8DOI Listing
October 2018
2 Reads

Serum thyroid hormones levels are significantly decreased in pregnant rats with acute pancreatitis.

Biochem Biophys Res Commun 2018 Nov 2;505(3):657-663. Epub 2018 Oct 2.

Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei, China. Electronic address:

Acute pancreatitis in pregnancy (APIP), which was thought to be a rare but severe disease, with a high perinatal mortality among maternal-fetuses. Our research aimed to study and assess thyroid injury in a rat model of APIP and its possible mechanisms. The APIP model was established by retrograde injection with sodium taurocholate. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X183212
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http://dx.doi.org/10.1016/j.bbrc.2018.09.180DOI Listing
November 2018
12 Reads
2.300 Impact Factor

[Treatment of Pancreatic Fluid Collections].

Korean J Gastroenterol 2018 Sep;72(3):97-103

Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Pancreatic Fluid Collection (PFC) develops as a result of acute pancreatitis, chronic pancreatitis, trauma, and postoperation. Although percutaneous drainage, surgery and Endoscopic Retrograde Panceatogram are used as conventional treatments in complicated PFC, the clinical course of PFC is unsatisfactory due to its clinical success rate and the risk of procedure-related complications. Endoscopic ultrasonography-guided transmural drainage of PFC is a safe and effective modality for the management of PFC, particularly in patients with pancreas necrosis. Read More

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http://dx.doi.org/10.4166/kjg.2018.72.3.97DOI Listing
September 2018
9 Reads