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HPB (Oxford) 2019 Apr 20. Epub 2019 Apr 20.

General and Digestive Surgery Department, Hepato-Bilio-Pancreatic Surgery Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San, Carlos (IdISSC), Madrid, Spain.

Introduction: Cholecystectomy is the treatment of choice for symptomatic cholelithiasis. However, outcomes for patients over 80years of age are not well studied. The primary aim of this study was to describe the safety and feasibility of cholecystectomy, including in the acute setting, in a cohort of patients≥80 years of age. Read More

J Trauma Acute Care Surg 2019 May;86(5):896-901

From the Hepatobiliary and Pancreatic Surgery Unit (R.P., T.V., K.S.), The Princess Alexandra Hospital, Woolloongabba, QLD; and The Whiteley-Martin Research Unit, Discipline of Surgery (R.P.), University of Sydney, Sydney, Australia.

Background: Extrahepatic bile duct injuries (EHBDIs) are a rare consequence of blunt abdominal trauma. The purpose of this study was to establish mechanisms of injury, clinical indicators of EHBDI following blunt trauma (both with investigative modalities and intraoperatively), method and timing of injury detection, and definitive treatment options.

Methods: A systematic review was performed to gather data on patients with an EHBDI secondary to blunt trauma. Read More

Clin Transplant 2019 Apr 18:e13571. Epub 2019 Apr 18.

VA Portland Health Care System, Operative Care Division, Section of Surgical Critical Care, Portland, OR.

Criteria for organ acceptance in brain dead organ donors remain inconsistent, especially when concerning pancreatic transplants. We sought to examine donor-specific predictors of pancreatic graft use and survival to better guide the selection and management of potential donors. A prospective observational study of all donors from ten organ procurement organizations was conducted from March 2012 to January 2015. Read More

Clin Ter 2019 Mar-Apr;170(2):e148-e161

Objectives: To explore the interaction between surgeon volumes (SVs) and hospital volumes (HVs) on health outcomes.

Materials And Methods: We searched MEDLINE, Embase, CINAHL, Web of Science as of May 2017. We included studies investigating the interaction between high or low SVs operating in high or low HVs. Read More

BMC Gastroenterol 2019 Apr 16;19(1):54. Epub 2019 Apr 16.

Department of Gastroenterology, Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.

Background: Conventionally, disconnected pancreatic duct syndrome is treated surgically. Endoscopic management is associated with lesser morbidity and mortality than that observed with surgery and shows similar success rates. However, limited data are available in this context. Read More

Medicine (Baltimore) 2019 Apr;98(15):e15127

Department of Pancreatic Surgery.

Rationale: Bile duct injury (BDI), a major complication of cholecystectomy, usually needs hepaticojejunostomy or primary repair over T-tube in severe cases. There were few cases about retained fragments of T-tube. Whereas, intact T-tube retained in common bile duct (CBD) for years after BDI was very rare. Read More

J Surg Res 2019 Apr 9;240:191-200. Epub 2019 Apr 9.

Department of Surgery, University of Wisconsin, Madison, Wisconsin.

Background: Transferred emergency general surgery (EGS) patients constitute a highly vulnerable, acutely ill population. Guidelines to facilitate timely, appropriate EGS transfers are lacking. We determined patient- and hospital-level factors associated with interhospital EGS transfers, a critical first step to identifying which patients may require transfer. Read More

Surg Infect (Larchmt) 2019 Apr 5. Epub 2019 Apr 5.

4 Department of Division of Trauma, Burns, Acute Care Surgery, and Surgical Critical Care, University of California, Irvine, Orange, California.

Background: Sepsis after emergency surgery is associated with a higher mortality rate than elective surgery, and total hospital costs increase by 2.3 times. This study aimed to identify risk factors for post-operative sepsis or septic shock in patients undergoing emergency surgery. Read More

Cureus 2019 Jan 19;11(1):e3922. Epub 2019 Jan 19.

Radiology, Aga Khan University Hospital, Karachi, PAK.

Objective The aim of this study was to describe the outcome of the use of interventional radiological procedures (IRP) (angioembolization) in critically injured children. Methods A retrospective review of medical records of all children who underwent an IRP from January 2010 to December 2015 was done. Data were collected on a structured proforma and results are presented as mean with standard deviation and frequency with percentages. Read More

Int J Surg Case Rep 2019 Mar 19;57:81-83. Epub 2019 Mar 19.

General Surgery, Rockingham General Hospital, Western Australia, Australia. Electronic address:

Introduction: Abdominal pain after colonoscopy is a relatively common symptom and usually benign. Colonoscopy-induced pancreatitis is an extremely rare phenomenon that can sometimes be missed leading to delayed diagnosis and treatment.

Presentation Of Case: A 53 year old woman presented to the Emergency Department with abdominal pain, a significantly raised lipase and a CT scan revealing pancreatitis. Read More

West Afr J Med 2019 Jan-Apr;36(1):80-82

General Surgery Unit, Department of Surgery, Faculty of Clinical Sciences College of Medicine, University of Lagos & Lagos University Teaching Hospital, PMB 12003, Idi-Araba. Lagos. Nigeria.

Pancreatic pseudocyst (PPC) complicating blunt and penetrating abdominal injury is well documented in paediatric age groups. In adults, PPC is often one of the sequelae of acute pancreatitis rather than trauma. Blunt abdominal trauma accounts for most documented cases of post-traumatic PPC. Read More

Radiol Case Rep 2019 May 16;14(5):639-645. Epub 2019 Mar 16.

Department of Radiology and Radiological Sciences, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29426, USA.

Traumatic pancreatic injuries are relatively uncommon in the setting of trauma, however, early detection of these injuries can alter patient management and overall prognosis. Computed tomography is the first line imaging modality in major trauma. Because failure to recognize pancreatic or main pancreatic duct injuries can lead to mismanagement, magnetic resonance imaging (MRI) can be a useful adjunct study in appropriate patients. Read More

Cancer Lett 2019 Jun 23;452:203-212. Epub 2019 Mar 23.

Molecular OncoSurgery, Section Surgical Research, Department of General, Visceral & Transplant Surgery, University of Heidelberg, Heidelberg, Germany. Electronic address:

NF-κB contributes to the aggressiveness of pancreatic ductal adenocarcinoma (PDA), which is counteracted by the bioactive agent sulforaphane. We investigated sulforaphane-induced microRNA signaling and its influence on progression features. Using established cell lines, microRNA and gene arrays, we predicted miR-365a as the top candidate for the sulforaphane-induced inhibition of the NF-κB subunit c-Rel. Read More

Cureus 2019 Jan 11;11(1):e3870. Epub 2019 Jan 11.

Surgery, Kings College Hospital, London, GBR.

A case of blunt pancreatic trauma during a soccer match is presented in a young adult female. Following diagnosis, a laparotomy was performed and multiple abdominal drains placed. A controlled pancreatic fistula occurred, which was treated conservatively. Read More

Lancet HIV 2019 Apr 14;6(4):e221-e229. Epub 2019 Mar 14.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

Background: Untreated opioid addiction in people with HIV is associated with poor HIV treatment outcomes. Slow-release, long-acting, implantable naltrexone might improve these outcomes. Here, we present results of a study aimed to test this hypothesis. Read More

Transplant Proc 2019 Mar 3;51(2):538-540. Epub 2019 Jan 3.

Department of Surgery, Division of Renal and Pancreas Transplant, Saint Barnabas Medical Center, Livingston, New Jersey, USA.

Iliac artery dissection in the setting of renal transplant is a rare but potentially catastrophic event that may result in loss of kidney and lower extremity perfusion. We report a right external iliac artery dissection in a 45-year-old man with end-stage renal disease, diabetes, and hypertension who underwent a renal transplant at our institution. An external iliac artery dissection was diagnosed intraoperatively after completion of the arterial anastomosis given the mottled appearance of the kidney and loss of Doppler signal. Read More

J Laparoendosc Adv Surg Tech A 2019 Mar 13. Epub 2019 Mar 13.

1 Department of Pediatric Surgery, Capital Institute of Pediatrics, Beijing, P.R. China.

Background/purpose: During laparoscopic excision of choledochal cysts (CDCs), if duodenum injury is encountered, conversion to open repair of duodenal injury is often the standard approach. This study evaluates if it is safe to repair the duodenal injury laparoscopically in CDC children.

Materials And Methods: CDC children who underwent single-incision laparoscopic repair for iatrogenic duodenal injury between October 2013 and September 2018 were reviewed. Read More

Surg Oncol Clin N Am 2019 04 10;28(2):255-272. Epub 2019 Feb 10.

Department of General Surgery, Mayo Clinic, Davis 3N, 4500 San Pablo Road, Jacksonville, FL 32224, USA; Miami Cancer Institute, 8900 North Kendall Drive, Miami, FL 33176, USA; Mayo Clinic College of Medicine and Sciences, 200 First Street South West, Rochester, MN 55905, USA.

In pancreatic cancer, resection combined with neoadjuvant and/or adjuvant therapy remains the only chance for cure and/or prolonged survival. A minimally invasive approach to pancreatic cancer has gained increased acceptance and popularity. The aim of minimally invasive surgery of the pancreas includes limiting trauma, decreasing length of hospitalization, lessening cost, decreasing blood loss, and allowing for a more meticulous oncologic dissection. Read More

Chin J Traumatol 2019 Feb 14;22(1):1-11. Epub 2019 Feb 14.

The First Affiliated Hospital of Third Military Medical University, Chongqing, China.

Vacuum sealing drainage (VSD) is frequently used in abdominal surgeries. However, relevant guidelines are rare. Chinese Trauma Surgeon Association organized a committee composed of 28 experts across China in July 2017, aiming to provide an evidence-based recommendation for the application of VSD in abdominal surgeries. Read More

J Korean Neurosurg Soc 2019 Mar 27;62(2):153-165. Epub 2019 Feb 27.

Neurosurgery Clinic, Gaziosmanpasa Taksim Training and Research Hospital, İstanbul, Turkey.

Objective: Spinal cord injury (SCI) is a very serious health problem, usually caused by a trauma and accompanied by elevated levels of inflammation indicators. Stem cell-based therapy is promising some valuable strategies for its functional recovery. Nestinpositive progenitor and/or stem cells (SC) isolated from pancreatic islets (PI) show mesenchymal stem cell (MSC) characteristics. Read More

Heliyon 2019 Feb 6;5(2):e01197. Epub 2019 Feb 6.

Dairy Science Department, National Research Centre, Dokki, Cairo, Egypt.

Hyperglycemia, the mark normal for diabetes and associated disorders are the main goals of natural diabetes therapies. In this context, the present research was designed to study the effects of fenugreek sprouts juice (FS), barley sprouts juice (BS), cell-free probiotic extract (cell-free PE), whey protein hydrolysate (WPH) and their mixture on diabetic rats. Free radical scavenging activity, total phenolic contents (TPC) and total flavonoid contents (TFC) of each item mentioned were determined. Read More

Scand J Surg 2019 Mar 4:1457496919833220. Epub 2019 Mar 4.

Abdominal Center, Meilahti Hospital, University of Helsinki, Helsinki, Finland.

Background And Aims:: Today, a significant proportion of solid abdominal organ injuries, whether caused by penetrating or blunt trauma, are managed nonoperatively. However, the controversy over operative versus nonoperative management started more than a hundred years ago. The aim of this review is to highlight some of the key past observations and summarize the current knowledge and guidelines in the management of solid abdominal organ injuries. Read More

Am J Transplant 2019 Feb;19 Suppl 2:124-183

Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN.

In 2017, 1492 patients were added to the pancreas transplant waiting list, 964 listed as active, a slight increase from 2016. This is significant because for the first time in the past decade, the steady downward trend in additions to the waiting list has been reversed. Proportions of pancreas donors with cerebrovascular accident as cause of death decreased, with a concomitant increase in proportions with anoxia and head trauma. Read More

Scand J Surg 2019 Feb 20:1457496919828244. Epub 2019 Feb 20.

1 Department of Orthopedics and Traumatology, Trauma Unit, Töölö Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Background And Aims:: Blunt abdominal trauma can lead to substantial organ injury and hemorrhage necessitating open abdominal surgery. Currently, the trend in surgeon training is shifting away from general surgery and the surgical treatment of blunt abdominal trauma patients is often done by sub-specialized surgeons. The aim of this study was to identify what emergency procedures are needed after blunt abdominal trauma and whether they can be performed with the skill set of a general surgeon. Read More

Case Rep Gastrointest Med 2019 15;2019:4587371. Epub 2019 Jan 15.

Division of Gastroenterology, Department of Medicine, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, PA, USA.

We report a case of acute pancreatitis after an elective screening colonoscopy. A 51-year-old male with a left ventricular assist device for end-stage nonischemic cardiomyopathy and a family history of colorectal cancer was admitted for an expedited heart transplant evaluation. He underwent screening colonoscopy during this admission which was technically uncomplicated apart from requiring slight maneuvering at the splenic flexure. Read More

Curr Treat Options Gastroenterol 2019 Mar;17(1):165-170

Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, GA, USA.

Surg Radiol Anat 2019 Mar 5;41(3):351-353. Epub 2019 Feb 5.

Department of Anatomy, Melaka Manipal Medical College (Manipal Campus), Manipal Academy of Higher Education, Manipal, India.

The left gastroepiploic artery (LGEA) is the least described artery in the medical literature. Unusual variations of this artery might lead to vascular injuries, causing intraoperative bleeding after surgery. We observed rare vascular variations in an adult male cadaver. Read More

Cureus 2018 Nov 17;10(11):e3604. Epub 2018 Nov 17.

General Surgery, Jinnah Postgraduate Medical College, Karachi, PAK.

Introduction Abdominal injuries are responsible for 10% of the mortalities due to trauma. Delays in early diagnosis or misdiagnoses are two major reasons for the mortality and morbidity associated with abdominal trauma. The objectives of this study were to determine the frequency of visceral injuries in patients with abdominal trauma and compare the frequency of visceral injuries in patients with blunt and penetrating abdominal trauma. Read More

Surg Case Rep 2019 Jan 23;5(1):10. Epub 2019 Jan 23.

Department of Surgical Oncology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.

Background: Pancreatic injuries are rare, and no treatment plan has yet been established for grade III injuries. In many cases, pancreatic stent placement has resulted in saving patients. However, some cases of perforation of a pancreatic duct during the placement of a stent have been described, and there are also a few cases of delayed perforation by a pancreatic stent. Read More

Int J Nanomedicine 2019 3;14:339-351. Epub 2019 Jan 3.

Department of Pharmaceutical Chemistry, Medical College, Shantou University, Shantou, PR China.

Background: Hepatic ischemia/reperfusion-induced pancreatic islet injury (HI/RIPII) was an important pathophysiological phenomenon in clinics. In the present study, we observed the effects of phycocyanin on HI/RIPII. However, the half-life of phycocyanin was extremely short and limited its use in vivo. Read More

CVIR Endovasc 2018 28;1(1). Epub 2018 Jun 28.

2University College London Hospital, Euston Road, London, NW1 2BU UK.

Background: Haemobilia, defined as bleeding from the biliary tree, is a rare entity. The most common cause of haemobilia is iatrogenic trauma, which accounts for 70% of cases. Pseudoaneurysms of the portal vein are an extremely rare cause of haemobilia with only four reported cases to date. Read More

Molecules 2019 Jan 15;24(2). Epub 2019 Jan 15.

Department of Orthopedics and Trauma Surgery, University of Duisburg-Essen, 45147 Essen, Germany.

The aim of this study was to elucidate the impact of autologous umbilical cord blood cells (USSC) on bone regeneration and biomechanical stability in an ovine tibial bone defect. Ovine USSC were harvested and characterized. After 12 months, full-size 2. Read More

Korean J Gastroenterol 2018 Dec;72(6):308-312

Division of Gastroenterology, Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.

Percutaneous endoscopic gastrostomy (PEG) is widely used to provide nutritional support for patients with dysphagia and/or disturbed consciousness preventing oral ingestion, and PEG tube placement is a relatively safe and convenient non-surgical procedure performed under local anesthesia. However, the prevention of PEG-insertion-related complications is important. A 64-year-old man with recurrent pneumonia underwent tracheostomy and nasogastric tube placement for nutritional support and opted for PEG tube insertion for long-term nutrition. Read More

J Trauma Acute Care Surg 2019 Jan 8. Epub 2019 Jan 8.

Hepatobiliary and Pancreatic Surgery Unit, Level 4, The Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, 4102, QLD.

Background: Extra-hepatic bile duct injuries (EHBDIs) are a rare consequence of blunt abdominal trauma. The purpose of this study was to establish mechanisms of injury, clinical indicators of EHBDI following blunt trauma (both with investigative modalities and intraoperatively), method and timing of injury detection, and definitive treatment options.

Method: A Systematic Review was performed to gather data on patients with an extrahepatic bile duct injury secondary to blunt trauma. Read More

Dig Dis Sci 2019 Jan 4. Epub 2019 Jan 4.

Department of General Surgery, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, 430060, Hubei province, China.

Objectives: The present study aimed to determine whether intestinal epithelial cell (IECs) apoptosis could be induced by endoplasmic reticulum stress (ERS) in severe acute pancreatitis (SAP), and the role of chemical chaperone 4-phenylbutyric acid (4-PBA) in SAP-associated intestinal barrier injury.

Methods: Twenty-four male Sprague Dawley rats were randomly divided into three groups: the sham operation group, the SAP group, and the SAP model plus 4-PBA treatment group (4-PBA group). A rat model of SAP was induced by retrograde injection of 5% sodium taurocholate (STC) into the biliopancreatic duct; in the 4-PBA group, 4-PBA was injected intraperitoneally at a dose of 50 mg/kg body weight for 3 days before modeling. Read More

Surg Radiol Anat 2019 Mar 3;41(3):339-341. Epub 2019 Jan 3.

General, Digestive, and Endocrine Surgery, Nouvel Hôpital Civil, Université de Strasbourg, 1 Place de L'hôpital, 67100, Strasbourg, France.

Aberrant splenic artery originating from the superior mesenteric artery (SMA) is extremely rare and recognition of this anomaly is important in the pre-operative planning of complex surgery such as pancreatic surgery, liver transplantation and vascular surgery. We present the case of an 80-year-old female diagnosed as septic shock due to mesenteric ischemia and obstructive pyelonephritis. Her splenic artery was originating from the SMA and the anomaly was readily appreciated on the pre-operative CT images. Read More

BMJ Case Rep 2018 Dec 31;11(1). Epub 2018 Dec 31.

General Surgery, Helios Klinikum Berlin-Buch, Berlin, Germany.

The mesenchymal chondrosarcoma (MC) is a rare malignant tumour and accounts for less than 3% of primary chondrosarcomas. Mostly MC arises from the craniofacial bones, the ribs, the ilium, the femur and the vertebrae. A 54-year-old man was treated due to an icterus of unknown origin. Read More

Oxid Med Cell Longev 2018 25;2018:9150807. Epub 2018 Nov 25.

College of Life Science, Shandong Agricultural University, Tai'an 271018, China.

The present work was performed to evaluate the effect of acidic-extractable polysaccharides (AE-PS) from fruit bodies of on type 2 diabetes mellitus (T2DM) and its structural characteristics. The T2DM mice induced by high-fat diet (HFD) and streptozotocin (STZ) were administered with 100 and 400 mg/kg AE-PS for 4 weeks. Our work proved that AE-PS decreased the levels of serum lipid, lipid peroxidation, and blood glucose; improved glucose and insulin resistance; enhanced antioxidant enzyme activities; and attenuated the injuries of the liver, kidney, and pancreas in T2DM mice. Read More

Asian J Surg 2019 Mar 25;42(3):524-525. Epub 2018 Dec 25.

Key Laboratory of Molecular Pathology, Inner Mongolia Medical University, #5, Xin Hua Street, Huhhot 010059, PR China. Electronic address:

World J Gastroenterol 2018 Dec;24(46):5280-5287

Department of Interventional Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Aim: To evaluate a 3D-printed coplanar template for iodine-125 seed implantation therapy in patients with pancreatic cancer.

Methods: A retrospective analysis of our database was performed, and a total of 25 patients with pancreatic cancer who underwent iodine-125 seed implantation between January 2014 and November 2017 were analyzed. Of these, 12 implantations were assisted by a 3D-printed coplanar template (group A), and 13 implantations performed freehand were selected as a control group (group B). Read More

Biomed J 2018 10 3;41(5):328-332. Epub 2018 Nov 3.

Faculty of Biological Sciences, Department of Physiology, Pontifical Catholic University of Chile, Santiago, Chile.

Background: Type 2 diabetes (T2D) can go undiagnosed for years, leading to a stage where produces complications such as delayed skin wound healing. Animal models have been developed in the last decades to study the pathological progression in this disease. Streptozotocin (STZ), that has a selective pharmacological toxicity toward pancreatic β cells, in addition to high fat diet has been widely used to induce diabetes however no evidence has shown its effects on the skin integrity. Read More

Transplant Proc 2018 Dec 29;50(10):4087-4089. Epub 2018 May 29.

Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN. Electronic address:

Background: Vascular complications represent the most common cause of early graft failure after pancreatic transplantation (PT). Pseudoaneurysms are uncommon vascular complications that usually present within the first year post transplantation.

Case Report: A 49-year-old man with history of type 1 diabetes mellitus presented for evaluation with a 2-day history of painless hematochezia. Read More

BMJ Case Rep 2018 Dec 10;11(1). Epub 2018 Dec 10.

Surgery, JCHO Chukyo Hospital, Nagoya, Japan.

Rupture of the common bile duct because of blunt trauma is extremely rare. Preoperative diagnosis is very difficult because bile causes little peritoneal irritation. We present a case of a 19-year-old young woman with rupture of the common bile duct due to blunt trauma. Read More

Diagn Interv Imaging 2019 Feb 13;100(2):65-75. Epub 2018 Dec 13.

General, Emergency and Robotic Surgery Unit, San Francesco Hospital, 08100 Nuoro NU, Italy.

Purpose: This purpose of this systematic review was to determine the safety and efficacy of arterial embolization as the primary treatment for grade III-V liver trauma, excluding the postoperative use of arterial embolization.

Material And Methods: A total of 24 studies published between January 2000 and June 2018 qualified for inclusion in this study. Four of them were prospective studies and 20 were retrospective. Read More

Biomed Pharmacother 2019 Jan 5;109:815-822. Epub 2018 Nov 5.

Department of Occupational and Environmental Health, Dalian Medical University, 9 W Lvshun South Road, Dalian 116044, PR China. Electronic address:

Arsenic was an established carcinogen and toxicant, occurring in drinking water and food. Arsenic was increasingly being blamed as a risk factor for diabetes mellitus. Recent studies have found that arsenic could induce the generation of reactive oxygen species (ROS) and mitochondria were the major targets of ROS. Read More

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2018 Nov;30(11):1077-1082

Department of General Surgery, People's Hospital of Qinghai Province, Xining 810007, Qinghai, China (Zhu HH, Zhu WJ, Guo YM); Department of Hepatobiliary Surgery, Tangshan Gongren Hospital, Tangshan 063000, Hebei, China (Pan MS). Corresponding author: Guo Yamin, Email:

Objective: To observe the indexes of liver injury and the expression of inflammation-related factor interleukin-10 (IL-10) in rats with severe acute pancreatitis (SAP), and to discuss the correlation between the expression of IL-10 and the related factors of liver injury in SAP rats at different altitudes.

Methods: 280 male Wistar rats with SPF grade aged 5 to 6 months were divided into four groups according to random number table with 70 rats in each group, and the rats were placed in different altitudes such as Xi'an (at an altitude of 1 027 m), Xining (at an altitude of 2 260 m), Xinghai (at an altitude of 3 300 m) and Wenquan (at an altitude of 3 950 m). The rats in each altitude were randomly divided into sham operation group (Sham group, n = 10) and SAP 1, 6, 12, 24 hours groups (all n = 15). Read More

Wideochir Inne Tech Maloinwazyjne 2018 Dec 30;13(4):460-468. Epub 2018 May 30.

2 Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland.

Introduction: Throughout our 20 years of experience, we have used several different techniques for laparoscopic splenectomy (LS). However, two methods have been used most frequently: "vessels first" and "hilar transection".

Aim: To evaluate the outcomes of LS performed with these two different approaches. Read More

J Trauma Acute Care Surg 2019 Mar;86(3):392-396

From the Virginia Commonwealth University (P.F., L.W., R.I.), Richmond, Virginia; Tulane University (J.D.), New Orleans, Louisiana; University of Campinas (G.P.F., B.M.P.), Campinas, Brazil; Keck School of Medicine (E.B., A.A.), University of Southern California, Los Angeles, California; University of San Francisco (A.C., C.W.), San Francisco, California; Clinical Research Center (A.G.), Fundación Valle del Lili, Cali, Colombia; Universidad de Antioquia-Hospital Universitario San Vicente Fundación (C.M.J.C.), Medellin, Colombia; Hospital Geral Grajaú-Universidade Santo Amaro (M.R.), São Paulo, Brazil; Hospital Santo Tomas (M.Q.), Cuidada de Panamá, Panamá; Robert Wood Johnson Medical School (G.P.); Hospital Vicente Corral Moscoso-Universidad del Azuay (J.C.S.), Cuenca, Ecuador; and Shock Trauma Centre (T.S.), University of Maryland, College Park, Maryland.

Introduction: The operative management of duodenal trauma remains controversial. Our hypothesis is that a simplified operative approach could lead to better outcomes.

Methods: We conducted an international multicenter study, involving 13 centers. Read More

Colloids Surf B Biointerfaces 2019 Mar 30;175:91-97. Epub 2018 Nov 30.

CIRIMAT, Université de Toulouse 3 - Paul Sabatier, CNRS, Toulouse, France. Electronic address:

Alginate and chitosan are polysaccharides that are widely used in the biomedical field, especially as wound dressings. Controlled bioadhesion is an advanced functionality that offers the potential to reduce injuries due to the stripping-off of the biomaterial. Herein, we report the efficient grafting of poly-N(isopropylacryamide) (PNIPAM), a thermosensitive polymer that exhibits a lower critical solution temperature (LCST) at 32 °C on the alginate/chitosan polyelectrolyte complex (PEC) surface. Read More

J Gastroenterol 2019 Apr 5;54(4):347-358. Epub 2018 Dec 5.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, 17 Yong Waizheng Street, Donghu District, Nanchang, 330006, Jiangxi, China.

Background: The gut is implicated in the pathogenesis of acute pancreatitis (AP) and the infectious complications of AP are commonly associated with enteric bacteria, yet whether gut microbiota dysbiosis participants in AP severity remains largely unknown.

Methods: We collected clinical information and fecal samples from 165 adult participants, including 41 with mild AP (MAP), 59 with moderately severe AP (MSAP), 30 with severe AP (SAP) and 35 healthy controls (HC). The serum inflammatory cytokines and gut barrier indexes were detected. Read More