6,812 results match your criteria Pancreatic Trauma


Liver resection in Cirrhotic liver: Are there any limits?

Int J Surg 2020 Jul 8. Epub 2020 Jul 8.

Chairman of HPB Surgical Division. Miguel Servet University Hospital. Zaragoza, Spain.

Liver resection remains one of the most technically challenging surgical procedure in abdominal surgery due to the complex anatomical arrangement in the liver and its rich blood supply that constitutes about 20% of the cardiac output per cycle. The challenge for resection in cirrhotic livers is even higher because of the impact of surgical stress and trauma imposed on borderline liver function and the impaired ability for liver regeneration in cirrhotic livers. Nonetheless, evolution and advancement in surgical techniques as well as knowledge in perioperative management of liver resection has led to a substantial improvement in surgical outcome in recent decade. Read More

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http://dx.doi.org/10.1016/j.ijsu.2020.06.050DOI Listing

Surgical management of blunt pancreatic transection.

J Trauma Acute Care Surg 2020 Jul 8. Epub 2020 Jul 8.

Department of Emergency Medicine, Ushioda General Hospital, Yokohama, Japan.

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http://dx.doi.org/10.1097/TA.0000000000002880DOI Listing

Giant mesenteric fibromatosis associated with non-Hodgkin lymphoma. a case report and literature review.

Acta Chir Belg 2020 Jul 9:1-13. Epub 2020 Jul 9.

Department of General Surgery, Hospital Universitario Son Espases, Palma de Mallorca, Spain.

Background: Mesenteric fibromatosis is a benign locally-aggressive mesenchymal neoplasm that lacks the potential for metastasis. It is related to Gardner's Syndrome, previous trauma, abdominal surgery, and prolonged intake of oestrogen. Differentially diagnosing this from similar tumours is crucial in order for establishing the appropriate treatment and only immunohistochemical features can be used for a definitive diagnosis. Read More

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Open necrosectomy combined with continuous positive drainage and prophylactic diverting loop ileostomy for late infected pancreatic necrosis: a retrospective cohort study.

BMC Gastroenterol 2020 Jul 8;20(1):212. Epub 2020 Jul 8.

Department of General Surgery, Jinling clinical college of Nanjing Medical University, Nanjing, 210002, Jiangsu, China.

Background: To evaluate an innovative open necrosectomy strategy with continuous positive drainage and prophylactic diverting loop ileostomy for the management of late infected pancreatic necrosis (LIPN).

Methods: Consecutive patients were divided into open necrosectomy (ON) group (n = 23), open necrosectomy with colonic segment resection (ON+CSR) group (n = 8) and open necrosectomy with prophylactic diverting loop ileostomy (ON+PDLI) group (n = 11). Continuous positive drainage (CPD) via double-lumen irrigation-suction tube (DLIST) was performed in ON+PDLI group. Read More

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http://dx.doi.org/10.1186/s12876-020-01343-7DOI Listing

Astragaloside IV as Potential Antioxidant Against Diabetic Ketoacidosis in Juvenile Mice Through Activating JNK/Nrf2 Signaling Pathway.

Authors:
Li-Li Deng

Arch Med Res 2020 Jul 2. Epub 2020 Jul 2.

Children's Intensive Care Unit, Chenzhou No. 1 People's Hospital, Chenzhou, Hunan, P.R. China. Electronic address:

Object: Astragaloside IV (AS IV) has antioxidative and anti-apoptotic properties, however, its effects on juvenile mice with diabetic ketoacidosis (DKA) have not been determined. This study aims to explore the effect and mechanism of Astragaloside IV (AS-IV) on juvenile mice with DKA.

Methods: DKA model was established through intraperitoneal injection of streptozotocin (STZ) and alloxan (ALX). Read More

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http://dx.doi.org/10.1016/j.arcmed.2020.06.013DOI Listing

Expanding indications for pancreatic islet cell transplantation.

Curr Opin Gastroenterol 2020 Jun 28. Epub 2020 Jun 28.

Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.

Purpose Of Review: We aimed to summarize the current state of performing pancreatic islet autotransplantation (IAT) for indications other than total pancreatectomy for chronic pancreatitis.

Recent Findings: The current article will review expanded indications for IAT including partial pancreatectomy for benign inflammatory disease, trauma, pancreatic islet cell tumor and pancreatic adenocarcinoma. In the context of more access for IAT as more centers are offering this clinical service, these expanded indications will continue to push the limits of our ability to make IAT accessible. Read More

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http://dx.doi.org/10.1097/MOG.0000000000000660DOI Listing

A study on the management of needle-stick and sharps injuries based on total quality management in a tertiary hospital in western China.

J Vasc Access 2020 Jul 3:1129729820936911. Epub 2020 Jul 3.

Department of Clinical Research Center, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, PR China.

Objective: Based on the concept of total quality management, the practice of managing needle-stick and sharps injuries was analyzed to improve nursing quality.

Methods: Using total quality management, an improvement plan was completed. Standard operating procedures for infusion therapy and monitoring of the circulatory system were made to reduce the utilization of winged metal needles and the frequency of needle-stick injuries. Read More

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http://dx.doi.org/10.1177/1129729820936911DOI Listing

Exploring the neglected segment of the intestine: the duodenum and its pathologies.

Pol J Radiol 2020 8;85:e230-e244. Epub 2020 May 8.

Department of Radiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

Herein we reviewed the computed tomography (CT) findings of a spectrum of pathological entities affecting the duodenum. We discuss the CT findings of some congenital, inflammatory, traumatic, and neoplastic pathologies of the duodenum along with the conventional barium studies of selected conditions. Pathologies of this C-shaped intestinal segment, derived from both foregut and midgut, are often overlooked in clinical practice and radiological literature. Read More

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http://dx.doi.org/10.5114/pjr.2020.95477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315055PMC

Non-operative management of pancreatic trauma in adults.

Hepatobiliary Pancreat Dis Int 2020 Jun 11. Epub 2020 Jun 11.

Regional Hepato-Pancreato-Biliary Surgery Unit, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.hbpd.2020.06.005DOI Listing

Nonneoplastic Lesions of the Pancreas: A Retrospective Analysis of 20 Cases.

Sisli Etfal Hastan Tip Bul 2018 30;52(1):31-35. Epub 2018 Mar 30.

Department of Pathology, Istanbul Sisli Hamidiye Etfal Application and Research Center, University of Health Sciences, Istanbul, Turkey.

Objectives: In the pancreatic lesion cases, surgery is often planned based only on imaging results and without a preoperative histological diagnosis, due to the high risk of malignancy in combination with the difficulty of invasive interventions and limited cytopathological evaluation. In this study, the records of 20 patients who had undergone a pancreatectomy procedure and who were diagnosed with nonneoplastic pancreatic lesions were retrospectively evaluated according to the clinical and histopathological findings.

Methods: A total of 122 cases of patients who underwent a pancreatectomy with suspicious lesions between 2004 and 2016 were retrospectively assessed in detail using the clinical and histopathological findings. Read More

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http://dx.doi.org/10.14744/SEMB.2017.88598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315078PMC

Left-sided portal hypertension caused by idiopathic splenic vein stenosis improved by splenectomy: a case report.

Surg Case Rep 2020 Jun 26;6(1):148. Epub 2020 Jun 26.

Division of Gastroenterological, Hepato-Biliary-Pancreatic, Transplantation and Pediatric Surgery, Department of Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.

Background: Splenic vein stenosis and occlusion, which are known causes of left-sided portal hypertension, often occur secondary to trauma, pancreatitis, or invasion or compression by pancreatic tumors. However, few reports have described idiopathic splenic vein stenosis.

Case Presentation: A 70-year-old man was referred to our hospital for examination of isolated gastric varices. Read More

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http://dx.doi.org/10.1186/s40792-020-00912-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316945PMC

Pancreatico Duodenal Trauma in Children: Two-Year Experience at a Regional Referral Center and Tertiary Care Teaching Hospital.

J Indian Assoc Pediatr Surg 2020 May-Jun;25(3):151-154. Epub 2020 Apr 11.

Department of Pediatric Surgery, Nil Ratansircar Medical College and Hospital, Kolkata, West Bengal, India.

Background: Pancreatico-Duodenal injuries, though rare, pose a mighty challenge to the surgeon in both diagnosis and treatment. More so in children, where the patho-physiologic threshold is low. Added to this is the absence of any strong guidelines to guide and ensure standardised care in these children for best outcome. Read More

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http://dx.doi.org/10.4103/jiaps.JIAPS_64_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302464PMC

Metabolic Syndrome and Risk of Pancreatic Cancer: a Population-based Prospective Cohort Study.

Int J Cancer 2020 Jun 24. Epub 2020 Jun 24.

Clinical Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, China; Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, China.

Metabolic syndrome (MetS) and its components may link to pancreatic cancer risk, however, current epidemiological evidence is limited, and the potential mechanisms underlying the associations remain unclear. To investigate this, we carried out the prospective cohort study of 474 929 participants without a diagnosis of cancer based on UK Biobank dataset. MetS was defined according to the International Diabetes Federation criteria and pancreatic cancer was identified through linkage to U. Read More

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http://dx.doi.org/10.1002/ijc.33172DOI Listing

The bridge stenting-based internal drainage in pancreatic trauma patients with main pancreatic duct injury.

Updates Surg 2020 Jun 22. Epub 2020 Jun 22.

Department of Gastroenterology and Hepatology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, 610072, Sichuan Province, China.

Pancreatic trauma is associated with high mortality and morbidity, especially in main pancreatic duct (MPD) injuries. Here, we introduce a novel technique via the placement of bridge stenting-based internal drainage (BSID) along the injured MPD to restore pancreatic tissue integrity. Twelve patients with MPD injury underwent unobstructed BSID as physical support for healing. Read More

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http://dx.doi.org/10.1007/s13304-020-00807-5DOI Listing

Laparoscopic Resection of a Left Upper Quadrant Mass Leading to a Surprise Diagnosis.

Case Rep Surg 2020 30;2020:8365061. Epub 2020 May 30.

University of Maryland Community Medical Group, Easton, MD, USA.

. Resplenectomy is most commonly done for the treatment of recurrent idiopathic thrombocytopenic purpura (ITP) refractory to medical management due to the regrowth of a missed accessory spleen. . Read More

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http://dx.doi.org/10.1155/2020/8365061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284930PMC

Acute pancreatic injuries: A complication of Stevens-Johnson syndrome/toxic epidermal necrolysis associated with cytotoxic immune cell activation.

J Am Acad Dermatol 2020 Jun 16. Epub 2020 Jun 16.

Department of Dermatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, China. Electronic address:

Background: Complications involving internal organs are usually present in Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). However, pancreatic complications are rarely reported and studied.

Objective: To summarize clinical characteristics of SJS/TEN-associated acute pancreatic injuries (API) and to investigate underlying inflammatory mechanisms. Read More

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http://dx.doi.org/10.1016/j.jaad.2020.06.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297678PMC

Matrine attenuates heterotopic ossification by suppressing TGF-β induced mesenchymal stromal cell migration and osteogenic differentiation.

Biomed Pharmacother 2020 Jul 18;127:110152. Epub 2020 May 18.

Department of Orthopedics, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, 214062, China. Electronic address:

Purpose Of The Study: Heterotopic ossification (HO) is a debilitating disease characterized by extraskeletal bone formation. Active TGF-β recruits mesenchymal stromal cells (MSCs), which contribute to trauma-induced HO. Inhibiting TGF-β induced MSC migration and osteogenic differentiation could be a promising treatment for HO. Read More

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http://dx.doi.org/10.1016/j.biopha.2020.110152DOI Listing

Case report: Evisceration of abdomen after blunt trauma.

Int J Surg Case Rep 2020 Jun 1;72:207-211. Epub 2020 Jun 1.

King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Department of Surgery, Saudi Arabia.

Introduction: Abdominal evisceration is uncommon after blunt abdominal trauma; therefore, it warrants urgent laparotomy. We report a young adult male who sustained multiple injuries due to a high impact mechanism resulting in blunt abdominal injury and underwent numerous laparotomies.

Case Report: In a high-speed motorcycle accident, a twenty-six-year-old male sustained a direct, blunt injury to his abdomen, which resulted in a right hemothorax, perforation of the stomach, and small bowel. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.05.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298532PMC

Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site.

Emerg Microbes Infect 2020 Dec;9(1):1474-1488

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People's Republic of China.

The mutations in the SARS-CoV-2 virus genome during COVID-19 dissemination are unclear. In 788 COVID-19 patients from Zhejiang province, we observed decreased rate of severe/critical cases compared with patients in Wuhan. For mechanisms exploration, we isolated one strain of SARS-CoV-2 (ZJ01) from a mild COVID-19 patient. Read More

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http://dx.doi.org/10.1080/22221751.2020.1781551DOI Listing
December 2020

Interactions Between Neutrophils and Platelets in the Progression of Acute Pancreatitis.

Pancreas 2020 Jul;49(6):830-836

From the Department of Gastroenterological Surgery.

Objective: Severe acute pancreatitis is a serious disease, but its detailed mechanism has not yet been elucidated. We aimed to clarify the interaction between neutrophils and platelets in the pathogenesis of acute pancreatitis.

Methods: We induced acute pancreatitis in rats by injection of sodium taurocholate into the biliopancreatic duct and killed them over time. Read More

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http://dx.doi.org/10.1097/MPA.0000000000001585DOI Listing

[Role of autophagy in pancreatic injury in sepsis].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2020 Apr;32(4):504-507

Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, China.

Sepsis is a life-threatening systemic inflammatory response syndrome (SIRS) caused by the host's maladjustment response to infection, which eventually leads to septic shock and multiple organ failure. Pancreatic injury was found to be an important pathological change in sepsis. Autophagy is a crucial way to maintain the normal metabolism of cell substances and energy, which plays an important role in many diseases. Read More

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http://dx.doi.org/10.3760/cma.j.cn121430-20191021-00063DOI Listing

Total Pancreatectomy and Pancreatic Allotransplant in a Porcine Experimental Model.

Exp Clin Transplant 2020 Jun;18(3):353-358

From the Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes, Nantes, France.

Objectives: The main objective of this experimental study was to evaluate the feasibility of diabetes induction by total pancreatectomy and pancreatic allotransplant after diabetes induction by total pancreatectomy. The secondary objective was to evaluate metabolic (C-peptide, glycemia) and inflammatory (lactate and platelet levels) parameters after diabetes induction by total pancreatectomy and pancreatic allotransplant after total pancreatectomy.

Materials And Methods: The study protocol was approved by the French Minister of Research (APAFiS no. Read More

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http://dx.doi.org/10.6002/ect.2019.0291DOI Listing

Endoscopic cyst gastrostomy for traumatic pancreatic pseudocysts in children: a case series.

Trauma Surg Acute Care Open 2020 8;5(1):e000456. Epub 2020 Apr 8.

Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.

Background: Pancreatic pseudocysts may develop after high-grade pancreatic injuries in children. Many resolve without intervention, and the management of symptomatic pseudocysts that persist remains controversial, with various open, percutaneous and laparoscopic approaches to intervention described. Successful endoscopic cyst gastrostomy has been reported in children with pancreatic pseudocysts of mixed etiology. Read More

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http://dx.doi.org/10.1136/tsaco-2020-000456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254115PMC

Radiological Society of North America (RSNA) 3D Printing Special Interest Group (SIG) clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: abdominal, hepatobiliary, and gastrointestinal conditions.

3D Print Med 2020 Jun 8;6(1):13. Epub 2020 Jun 8.

Department of Radiology and The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.

Background: Medical 3D printing has demonstrated value in anatomic models for abdominal, hepatobiliary, and gastrointestinal conditions. A writing group composed of the Radiological Society of North America (RSNA) Special Interest Group on 3D Printing (SIG) provides appropriateness criteria for abdominal, hepatobiliary, and gastrointestinal 3D printing indications.

Methods: A literature search was conducted to identify all relevant articles using 3D printing technology associated with a number of abdominal pathologic processes. Read More

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http://dx.doi.org/10.1186/s41205-020-00065-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278118PMC

Hypoglycemic potential of selenium nanoparticles capped with polyvinyl-pyrrolidone in streptozotocin-induced experimental diabetes in rats.

Heliyon 2020 May 30;6(5):e04045. Epub 2020 May 30.

Zoology and Entomology Department, Faculty of Science, Helwan University, Cairo, Egypt.

This study was aimed to evaluate the efficacy of synthesized selenium nanoparticles (SeNPs) capped with glucose and polyvinyl-pyrrolidone (PVP) on the hyperglycemia and prooxidants/antioxidants imbalance present in model streptozotocin (STZ)-induced diabetic rats. SeNPs were synthesized and characterized. Twenty-four albino male rats were grouped into four different groups. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e04045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264054PMC

Diagnostic and therapeutic role of endoscopic retrograde pancreatography and stent placement for grade IV blunt pancreatic trauma: A case report.

Trauma Case Rep 2020 Aug 30;28:100319. Epub 2020 May 30.

Department of Digestive Surgery, Japanese Red Cross Okayama Hospital, 2-1-1 Aoe Kitaku, Okayama 700-8607, Japan.

Pancreatic trauma involving ductal injury is rare but is associated with high morbidity and mortality. The benefit of endoscopic retrograde pancreatography and stent placement is unclear because there are only a few case reports on endoscopically treated pancreatic duct transection at the pancreatic head. We report a rare case of grade IV pancreatic trauma successfully treated with endoscopic pancreatic stent, which we believe makes significant contribution to the existing literature. Read More

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http://dx.doi.org/10.1016/j.tcr.2020.100319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264759PMC

Mind the gaps: age and cause specific mortality and life expectancy in the older population of South Korea and Japan.

BMC Public Health 2020 Jun 1;20(1):819. Epub 2020 Jun 1.

Department of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul, South Korea.

Background: Recent life expectancy gains in high-income Asia-pacific countries have been largely the result of postponement of death from non-communicable diseases in old age, causing rapid demographic ageing. This study compared and quantified age- and cause-specific contributions to changes in old-age life expectancy in two high-income Asia-pacific countries with ageing populations, South Korea and Japan.

Methods: This study used Pollard's actuarial method of decomposing life expectancy to compare age- and cause-specific contributions to changes in old-age life expectancy between South Korea and Japan during 1997 and 2017. Read More

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http://dx.doi.org/10.1186/s12889-020-08978-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268756PMC

Correlation of microRNA-146a/b with disease risk, biochemical indices, inflammatory cytokines, overall disease severity, and prognosis of sepsis.

Medicine (Baltimore) 2020 May;99(22):e19754

Department of Hepatobiliary & Pancreatic Surgery, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Background: Previous studies have indicated the association of microRNA-146a/b (miR-146a/miR-146b) with pro-inflammatory cytokines production, lipopolysaccharide-mediated injuries and organ dysfunction, however, the correlation of miR-146a/miR-146b with disease risk, disease severity, biochemical indices, inflammatory cytokines and mortality of sepsis has not been explored, which was investigated in the present study.

Methods: In total, 180 sepsis patients and 180 healthy controls were enrolled. The peripheral blood samples were collected from sepsis patients within 24 hour after admission and from healthy controls at enrolment. Read More

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http://dx.doi.org/10.1097/MD.0000000000019754DOI Listing

Conservative management of complete traumatic pancreatic body transection; A case report.

Int J Surg Case Rep 2020 21;71:222-224. Epub 2020 May 21.

St Vincent's University Hospital, 196 Merrion Road, Elm Park, Dublin, Ireland.

Introduction: Isolated pancreatic body transection secondary to blunt abdominal trauma is a very rare injury associated with poor outcomes. Almost all previously reported cases were managed by emergency distal pancreatectomy, which is associated with high morbidity and mortality. To our knowledge, this is the first reported case of complete transection of the pancreas at the body that was successfully treated by conservative management in an adult patient. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262372PMC

Virtual monochromatic reconstructions of dual energy CT in abdominal trauma: optimization of energy level improves pancreas laceration conspicuity and diagnostic confidence.

Emerg Radiol 2020 May 30. Epub 2020 May 30.

Department of Emergency and Trauma Radiology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.

Purpose: Pancreatic injury is associated with significant morbidity and mortality. Pancreatic lacerations can be challenging to identify as the pancreas is not scanned at peak enhancement in most trauma CT protocols. This study qualitatively and quantitively assessed pancreatic lacerations with virtual monoenergetic dual-energy CT (DE CT) to establish an optimal energy level for visualization of pancreatic lacerations. Read More

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http://dx.doi.org/10.1007/s10140-020-01791-4DOI Listing

Evidenced-Based Practice Among Trainees: A Survey on Facial Trauma Wound Management.

J Surg Educ 2020 May 25. Epub 2020 May 25.

Division of General Surgery, Department of Surgery, Stanford University, Stanford, California.

Objective: Assess whether facial trauma wound care and antibiotic use recommendations are guided by evidence-based practice (EBP) or practice patterns, and investigate strategies to improve EBP adoption among surgical trainees.

Design: We conducted a survey of all trainees who manage facial trauma (general surgery, emergency medicine, plastic surgery, otolaryngology) to assess clinical knowledge and sources of treatment recommendations. Clinical questions were based on Oxford Center for Evidence-Based Medicine Level 1 or 2 evidence. Read More

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http://dx.doi.org/10.1016/j.jsurg.2020.03.015DOI Listing

COVID-19 and diabetes: The why, the what and the how.

J Diabetes Complications 2020 May 22:107637. Epub 2020 May 22.

Department of Trauma and Orthopaedics, Mater Dei Hospital, Msida, Malta.

Background: The novel coronavirus SARS-CoV-2 has taken the world by storm. Alongside COVID-19, diabetes is a long-standing global epidemic. The diabetes population has been reported to suffer adverse outcomes if infected by COVID-19. Read More

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http://dx.doi.org/10.1016/j.jdiacomp.2020.107637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242955PMC

Subcapsular Renal Hematoma in Simultaneous Pancreas Kidney Transplantation.

Case Rep Transplant 2020 11;2020:6152035. Epub 2020 May 11.

Department of Clinical and Experimental Medicine, Division of Metabolism and Cell Transplantation, University of Pisa, Pisa, Italy.

Subcapsular renal hematoma (SRH) is a challenging condition, which may jeopardize kidney function or constitute a life-threatening event. This is particularly true in single-kidney patients, such as kidney-transplant recipients. SRH may exert an excessive pressure on the surrounding parenchyma, thus resulting in hypoperfusion and ischemia, with high risk of acute kidney failure and graft loss. Read More

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http://dx.doi.org/10.1155/2020/6152035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238346PMC

Expression of Pancreatic Stone Protein is Unaffected by Trauma and Subsequent Surgery in Burn Patients.

World J Surg 2020 May 25. Epub 2020 May 25.

Department of Plastic Surgery and Hand Surgery, Burn Center, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.

Background: Altered levels of pro-inflammatory markers secondary to trauma or surgery present a major problem to physicians in being prone to interfere with the clinical identification of infectious events.

Methods: Patients admitted to Zurich Burn Center between May 2015 and October 2018 with burns ≥10% total body surface area (TBSA) and without infection. Longitudinal analysis of the time course of PSP and routine inflammatory biomarkers [procalcitonin (PCT), C-reactive protein (CRP) and white blood cells (WBC)] over two days after (a) trauma with initial debridement and (b) subsequent burn surgeries was performed. Read More

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http://dx.doi.org/10.1007/s00268-020-05589-wDOI Listing

Management of pancreatic collections: an update.

Rev Esp Enferm Dig 2020 Jun;112(6):483-490

Gastroenterología y Hepatología, Hospital Universitario Ramón y Cajal. Unviersidad de Alcalá. IRYICIS, España.

Pancreatic fluid collections frequently occur in the context of moderate and severe acute pancreatitis, and may also appear as a complication of chronic pancreatitis, pancreatic surgery or trauma. It is essential to adhere to the Atlanta classification nomenclature that subclassifies them into four categories (acute peripancreatic fluid collections, acute necrotic collections, pseudocysts, and walled-off necrosis) since it has an impact on prognosis and management. Pseudocysts and walled-off pancreatic necrosis are encapsulated pancreatic fluid collections characterized by a surrounding inflammatory wall, which typically develops three to four weeks after the onset of acute pancreatitis. Read More

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http://dx.doi.org/10.17235/reed.2020.6814/2019DOI Listing

Does pendimethalin develop in pancreatic cancer induced inflammation?

Chemosphere 2020 Aug 29;252:126644. Epub 2020 Mar 29.

Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey. Electronic address:

Pendimethalin, one of the dinitroaniline group herbicides, is applied for controlling weeds in cereals, legumes and vegetable crops, and has been classified as possible human carcinogen. It is indicated that pendimethalin should arise risks of developing some cancer types; however, there is no data on the effects of pendimethalin on pancreatic cancer-induced inflammation. Injuries resulting from by acute pancreatitis attacks and inflammation are significant factors in the development of pancreatic cancer. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2020.126644DOI Listing

Intra-abdominal cystic lymphangioma of the mesocolon sigmoids: a rare entity in adult patient woman.

J Surg Case Rep 2020 May 15;2020(5):rjaa031. Epub 2020 May 15.

Medico, Ministerio de Salud Publica, Quito, Ecuador.

The lymphangioma is a benign neoplasm, mostly connate, it occurs more often in children. It is more frequently located in the head-neck region, as well as in the armpit, and less frequently in the abdomen. The diagnosis, as well as their appearance is variant, they can be asymptomatic depending on the size. Read More

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http://dx.doi.org/10.1093/jscr/rjaa031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229823PMC

MicroRNA-191 regulates differentiation and migration of mesenchymal stem cells and their paracrine effect on angiogenesis.

Biotechnol Lett 2020 May 20. Epub 2020 May 20.

School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan, 430070, Hubei Province, China.

MicroRNAs (miRNAs) are critical regulators in organ development. Among them, miR-191 is known to be regulated in early embryogenesis and dysregulated in cancer. This role in undifferentiated tissues suggests a possible part of miR-191 also in bone marrow derived mesenchymal stem cells (BMSCs) physiology. Read More

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http://dx.doi.org/10.1007/s10529-020-02907-zDOI Listing

Reasons for Low Utilization of Pancreas for Transplantation From Deceased Donors: Analysis of Data From a Single Center in India.

Transplant Proc 2020 May 17. Epub 2020 May 17.

Department of Renal Transplant Surgery, Nehru Building, Post Graduate Institute of Medical Education and Research, Chandigarh, India. Electronic address:

Objectives: Although pancreas transplants were started at our center in 2014, the number of pancreases procured have remained low. This report presents an audit of donors over the past 18 months with the aim to identify factors preventing pancreas utilization.

Methods: This was a retrospective study. Read More

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http://dx.doi.org/10.1016/j.transproceed.2020.04.002DOI Listing

How to deploy a uniform and simplified acute-phase management strategy for traumatic pancreatic injury in any situation.

Acute Med Surg 2020 Jan-Dec;7(1):e502. Epub 2020 Apr 13.

Department of Traumatology and Critical Care Medicine Osaka City University Graduate School of Medicine Osaka Japan.

Aim: Management of traumatic pancreatic injury is challenging, and mortality and morbidity remain high. Because pancreatic injury is uncommon and strong recommendations for pancreatic injury management are lacking, management is primarily based on institutional practices. We propose our strategy of pancreatic injury management. Read More

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http://dx.doi.org/10.1002/ams2.502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231571PMC

Computer-assisted real-time automatic prostate segmentation during TaTME: a single-center feasibility study.

Surg Endosc 2020 May 19. Epub 2020 May 19.

Surgical Device Innovation Office, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

Background: Urethral injuries (UIs) are significant complications pertaining to transanal total mesorectal excision (TaTME). It is important for surgeons to identify the prostate during TaTME to prevent UI occurrence; intraoperative image navigation could be considered useful in this regard. This study aims at developing a deep learning model for real-time automatic prostate segmentation based on intraoperative video during TaTME. Read More

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http://dx.doi.org/10.1007/s00464-020-07659-5DOI Listing

SAGES TAVAC safety and efficacy analysis confocal laser endomicroscopy.

Surg Endosc 2020 May 13. Epub 2020 May 13.

VIP Surg. PLLC., Las Vegas, NV, USA.

Background: Confocal laser endomicroscopy (CLE) is a novel endoscopic adjunct that allows real-time in vivo histological examination of mucosal surfaces. By using intravenous or topical fluorescent agents, CLE highlights certain mucosal elements that facilitate an optical biopsy in real time. CLE technology has been used in different organ systems including the gastrointestinal tract. Read More

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http://dx.doi.org/10.1007/s00464-020-07607-3DOI Listing

Two-stage pancreatic head resection after previous damage control surgery in trauma: two rare case reports.

BMC Surg 2020 May 12;20(1):98. Epub 2020 May 12.

Department of Surgery, Centro Hospitalar Universitário do Algarve - Unidade de Portimão, Portimão, Portugal.

Background: This study describes the successful treatment of two clinical settings of grade V pancreaticoduodenal blunt trauma only possible due to the prompt collaboration of a peripheral trauma hospital and a central hepatobiliary and pancreatic unit.

Case Presentation: We reviewed the clinical records of two male patients aged 17 and 47 years old who underwent a two-stage pancreaticoduodenectomy after a previous Damage-Control Surgery (DCS). Both patients were transferred to our Hepatobiliopancreatic Unit 2 days after immediate DCS with haemostasis, debridement, duodenostomy, gastroenterostomy, external drainage and laparostomy. Read More

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http://dx.doi.org/10.1186/s12893-020-00763-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216496PMC

Heterotopic accessory spleen with squamous epithelial cyst in pancreas mimicking other pancreatic tumor: a case report.

Ann Transl Med 2020 Apr;8(7):507

Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China.

A 49-year-old female undergoing a periodic health examination at other hospital revealed a mass in the tail of pancreas. The patient denied any personal history of surgery except subtotal hysterectomy because of multiple myomas in uterus 7 years ago, family history of abdominal cancer and trauma. Physical examination and laboratory finding (including tumor marker) were unremarkable. Read More

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http://dx.doi.org/10.21037/atm.2020.03.79DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210170PMC

Coronavirus Disease-19 (COVID-19) associated with severe acute pancreatitis: Case report on three family members.

Pancreatology 2020 Jun 5;20(4):665-667. Epub 2020 May 5.

Pancreatitis Centre East, Gastrounit, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark; Department of Clinical Medicine, University of Copenhagen, Denmark.

Background/objectives: Abdominal pain is one of the known symptoms associated with coronavirus disease 2019. Little is known about the development of acute pancreatitis as a complication of severe acute respiratory syndrome coronavirus 2 infection. This case report describes the presentation of acute pancreatitis in two of three family members with severe COVID-19 infection. Read More

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http://dx.doi.org/10.1016/j.pan.2020.04.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199002PMC

[A Surgical Case of Desmoid Tumor in the Transverse Mesocolon with Pancreatic Invasion].

Gan To Kagaku Ryoho 2020 Jan;47(1):71-75

Dept. of Surgery, NTT Medical Center Tokyo.

A 40-year-old man with no previous history of abdominal surgery or noteworthy family history presented to our hospital because of a palpable abdominal mass. Abdominal CT revealed a 9 cm diameter mass in the mesocolon. The differential diagnosis included desmoid tumor, and right hemicolectomy with partial resection of the pancreas head and duodenum was performed. Read More

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January 2020

Nontraumatic Multiple-Organ Fat Embolism: An Autopsy Case and Review of Literature.

Am J Forensic Med Pathol 2020 Jun;41(2):131-134

From the School of Forensic Medicine.

The patient was an 88-year-old woman with a 10-year history of hypertension. She was suspected to have been hit by a car. At the time of the event, she was conscious and able to stand on her own and had no obvious injuries. Read More

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http://dx.doi.org/10.1097/PAF.0000000000000544DOI Listing

Carbon Monoxide Being Hydrogen Sulfide and Nitric Oxide Molecular Sibling, as Endogenous and Exogenous Modulator of Oxidative Stress and Antioxidative Mechanisms in the Digestive System.

Oxid Med Cell Longev 2020 15;2020:5083876. Epub 2020 Apr 15.

Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Krakow, Poland.

Oxidative stress reflects an imbalance between oxidants and antioxidants in favor of the oxidants capable of evoking tissue damage. Like hydrogen sulfide (HS) and nitric oxide (NO), carbon monoxide (CO) is an endogenous gaseous mediator recently implicated in the physiology of the gastrointestinal (GI) tract. CO is produced in mammalian tissues as a byproduct of heme degradation catalyzed by the heme oxygenase (HO) enzymes. Read More

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http://dx.doi.org/10.1155/2020/5083876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180415PMC

The predictive role of amylase and lipase levels on pancreas injury diagnosis in patients with blunt abdominal trauma.

Horm Mol Biol Clin Investig 2020 May 6. Epub 2020 May 6.

Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Islamic Republic of Iran.

Objectives Despite the low incidence of pancreatic injury in the abdominal blunt trauma (BTA), its early diagnosis is very important; since pancreatic injury is associated with high rates of morbidity and mortality. However, due to the high association of pancreatic injury with injury of other abdominal organs, its diagnosis may be delayed and complicated. The use of imaging modalities is also subject to limitations for reasons such as cost, unavailability, and harmfulness. Read More

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http://dx.doi.org/10.1515/hmbci-2019-0066DOI Listing