463 results match your criteria Pancreatic Serous Cystadenoma Imaging

Cytologic Assessment of Cystic/Intraductal Lesions of the Pancreatobiliary Tract.

Michelle D Reid

Arch Pathol Lab Med 2021 Apr 9. Epub 2021 Apr 9.

From the Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia.

Context.—: Because of new and improved imaging techniques, cystic/intraductal pancreatobiliary tract lesions are increasingly being discovered, and brushings or endoscopic ultrasound/computed tomography/magnetic resonance imaging-guided fine-needle aspiration biopsies from these lesions have become an integral part of pathologists' daily practice. Because patient management has become increasingly conservative, accurate preoperative diagnosis is critical. Read More

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A Novel Treatment for Metastatic Serous Cystadenocarcinoma Using a Microwave Ablation: Case Report and Review of the Literature.

Pancreas 2021 Mar;50(3):434-440

From the Division of Surgical Oncology, Department of Surgery.

Abstract: The incidence of pancreatic cystic neoplasms has grown because of increased detection. Among these lesions, serous cystadenoma was traditionally thought to be universally benign and indolent. However, there is an exceedingly rare malignant variant of serous cystadenoma known as serous cystadenocarcinoma (SCAC) that can exhibit local invasion into adjacent structures, hepatic implants, and metastatic spread to the abdominal viscera. Read More

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Triple threat: pancreatic cystic lesion presenting with spontaneous hemorrhage is found to harbor three distinct neoplasms.

World J Surg Oncol 2021 Jan 15;19(1):15. Epub 2021 Jan 15.

HPB Surgery and Surgical Oncology, Valley Medical Group, Luckow Plaza, One Valley Health Plaza, Paramus, NJ, 07652, USA.

Background: Pancreatic serous cystadenoma (SCA) is a benign, cystic lesion with an indolent growth pattern. Complications such as spontaneous hemorrhage or malignant transformation from SCA are extremely rare. Our case report describes an unusual presentation of a patient with a previously diagnosed SCA, made unique by the presence of three separate neoplasms in the final specimen. Read More

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January 2021

Pancreatic serous cystoadenoma (CSA) showing increased tracer uptake at 68-GaDOTA-peptide Positron Emission Tomography (68Ga-DOTA-peptide PET-CT): a case report.

BMC Surg 2020 Dec 14;20(1):331. Epub 2020 Dec 14.

Pancreatic Surgery Unit, Humanitas Clinical and Research Center-IRCCS Rozzano, Via Alessandro Manzoni, 56, 20089, Rozzano, Milan, Italy.

Background: Serous cysto-adenoma (SCA) is a rare benign neoplasm of the pancreas. SCA can mimic other pancreatic lesions, such as neuroendocrine tumours. 68Gallium-DOTA-peptide Positron Emission Tomography (PET) is able to image in vivo the over-expression of the somatostatin receptors, playing an important role for the identification of neuroendocrine neoplasms. Read More

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December 2020

Differentiating benign from malignant pancreatic cysts on computed tomography.

Eur J Radiol Open 2020 1;7:100278. Epub 2020 Nov 1.

Second Affiliated Hospital, Department of Radiology, Sun Yat-sen University, Guangzhou 510000, China.

Purpose: It is important to identify features on computed tomography (CT) that can distinguish between benign and premalignant or malignant pancreatic cysts to avoid unnecessary surgeries. This study investigated the preoperative diagnostic evaluation of cystic pancreatic lesions to determine how advanced imaging and clinical factors should guide management.

Methods: In total, 53 patients with 27 benign and 26 premalignant or malignant cysts were enrolled. Read More

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November 2020

Role of volumetric multiparametric MRI in distinguishing between intraductal papillary mucinous neoplasms and serous cystadenoma.

Abdom Radiol (NY) 2021 04 9;46(4):1629-1639. Epub 2020 Oct 9.

Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA.

Purpose: To evaluate the use of volumetric multiparametric MRI in differentiating pancreatic intraductal papillary mucinous neoplasms (IPMNs) from serous cystadenomas (SCAs) METHODS: Included patients (123 patients with pancreatic cystic neoplasms (PCNs) measuring ≥ 10 mm) were stratified into two groups based on cyst type. Axial cyst size, region of interest (ROI)-based apparent diffusion coefficient (ADC) and volumetric data, including cyst volume, volumetric apparent diffusion coefficient (vADC), and volumetric venous enhancement (vVE) were extracted and compared between the two groups. Univariate and multiple logistic regression was used to develop models for distinguishing between IPMNs and SCAs. Read More

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Incidentally detected microcystic serous cystadenoma of the pancreas with splenic invasion: a case report and literature review.

BJR Case Rep 2020 Sep 29;6(2):20190109. Epub 2020 Sep 29.

Department of Diagnostic Radiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

Serous cystic neoplasms are relatively uncommon and rarely possess malignant potential. We report a rare case of pancreatic serous cystadenoma with splenic invasion in a female in her 60s. Dynamic contrast-enhanced CT revealed a 3 cm mass in the tail of the pancreas. Read More

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September 2020

Non-Neoplastic and Neoplastic Cysts of the Pancreas.

Monogr Clin Cytol 2020 28;26:53-73. Epub 2020 Sep 28.

Office of Chief Medical Examiner, New York, New York, USA.

Inflammatory, developmental, and neoplastic lesions may all present as cystic masses on imaging. Pseudocyst is the most common of these and presents in association with a history of pancreatitis. Pancreatic cystic neoplasms are uncommon compared to solid neoplasms. Read More

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September 2020

Laparoscopic Central Pancreatectomy with Pancreato-Gastric Anastomosis for Pancreatic Cystadenoma.

Chirurgia (Bucur) 2020 Jul-Aug;115(4):520-525

We present the case of a 42-year-old woman diagnosed with a cystic pancreatic lesion, suggestive of a serous cystadenoma of 27/13 mm. The diagnosis was established by the examination of abdominal CT and eco-endoscopy. The patient was referred to the surgery department for treatment. Read More

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October 2020

Pearls and pitfalls of imaging features of pancreatic cystic lesions: a case-based approach with imaging-pathologic correlation.

Jpn J Radiol 2021 Feb 25;39(2):118-142. Epub 2020 Aug 25.

Department of Radiology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.

A variety of neoplastic and non-neoplastic lesions of the pancreas can present with a predominantly cystic architecture. These lesions are increasingly being detected as incidental findings on routine cross-sectional imaging following technological advances in these techniques and their widespread use. The different histopathological behaviors show various common and uncommon imaging findings, and some cases show similar appearance in spite of different histopathology. Read More

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February 2021

Discrimination of serous cystadenoma from mucinous cystic neoplasm and branch duct intraductal papillary mucinous neoplasm in the pancreas with CT.

Abdom Radiol (NY) 2020 09 23;45(9):2772-2778. Epub 2020 Jul 23.

Department of Radiology, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, China.

Purpose: The imaging features of serous cystadenomas (SCAs) overlap with those of mucinous cystic neoplasms (MCNs) and branch duct intraductal papillary mucinous neoplasms (BD-IPMNs), and an accurate preoperative diagnosis is important for clinical treatment due to their different biological behaviors. The aim of this study was to provide a computed tomographic (CT) feature for the diagnosis of SCAs and estimate whether the "circumvascular sign" can contribute to the discrimination of SCAs from MCNs and BD-IPMNs.

Methods: From August 2011 through December 2019, a total of 71 patients (30 patients with 30 SCAs, 21 patients with 21 MCNs and 20 patients with 22 BP-IPMNs) were enrolled in this study. Read More

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September 2020

[Clinical diagnosis and treatment characteristics of pancreatic cystic neoplasms in pediatric patients: a report of 13 cases].

Zhonghua Wai Ke Za Zhi 2020 Jul;58(7):525-529

Department of General Surgery, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430014, China.

To investigate the clinical characteristics of pancreatic cystic neoplasms in pediatric patients. The clinical data of 13 patients with pancreatic cystic neoplasm at Wuhan Children's Hospital from July 2007 to November 2019 were collected.There were 5 males and 8 females, with a mean age of 133 months(range: 9 to 170 months). Read More

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Role of Cross-sectional Imaging (CT/MRI) in Characterization and Distinguishing Benign from Malignant/Potentially Malignant Cystic Lesions of Pancreas.

J Clin Imaging Sci 2020 16;10:28. Epub 2020 May 16.

Biostatistics, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

Objectives: The aim of the study was to evaluate the accuracy of computed tomography/magnetic resonance imaging (CT/MRI) in characterizing cystic lesions of the pancreas and in differentiating between benign and malignant/potentially malignant lesions.

Material And Methods: A retrospective study was performed on patients with pancreatic cystic lesions who underwent pre-operative imaging and surgery between October 2004 and April 2017 at a tertiary care teaching hospital. The images were reviewed for specific characteristics and diagnoses recorded independently by two radiologists who were blinded to the histopathological examination (HPE) report. Read More

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Solid pseudopapillary tumour should be part of differential diagnosis of focal pancreatic lesions with increased F-FDOPA uptake.

Clin Endocrinol (Oxf) 2020 07 5;93(1):78-81. Epub 2020 May 5.

Nuclear Medicine and Molecular Imaging, ICANS - University Hospitals of Strasbourg, Strasbourg, France.

Objective: To assess the specificity of increased F-dihydroxyphenylalanine ( F-FDOPA) uptake in patients who underwent PET/CT for suspicion of isolated pancreatic neuroendocrine tumour (pNET). False-positive results mimicking a pNET have been investigated.

Material And Methods: Carbidopa-assisted F-FDOPA PET/CT scans performed in patients with suspicion of localized pNET were retrieved. Read More

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Indocyanine Green-Enhanced Fluorescence in Laparoscopic Duodenum-Preserving Pancreatic Head Resection: Technique with Video.

Ann Surg Oncol 2020 Oct 7;27(10):3926-3927. Epub 2020 Apr 7.

Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China.

Background: In 1972, Beger et al.1 first described duodenum-preserving pancreatic head resection (DPPHR) for patients with severe chronic pancreatitis. Then DPPHR also was proved capable of providing comparable long-term oncologic outcomes in the setting of benign or low-grade malignant tumors. Read More

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October 2020

Similarities and differences in guidelines for the management of pancreatic cysts.

World J Gastroenterol 2020 Mar;26(11):1128-1141

Department of Gastroenterology, Hepatology, and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.

Accurate diagnosis of Pancreatic cysts (PC) is key in the management. The knowledge of indications for surgery, the role of endoscopic ultrasound-guided fine needle aspiration, cyst fluid analysis, imaging, and surveillance of PC are all important in the diagnosis and management of PC. Currently, there are many guidelines for the management of PC. Read More

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Pancreatic microcystic serous cystadenoma: a lethal disease? Rare case of a life-threatening haemorrhage.

BMJ Case Rep 2020 Mar 19;13(3). Epub 2020 Mar 19.

General Surgery Department, Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal.

Serous pancreatic cystadenomas are benign tumours and most cases are detected incidentally. Complications are unusual. A patient with a history of a large pancreatic serous cystadenoma (SCA) presented to the emergency department with abdominal pain and haemodynamic shock. Read More

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Molecular Diagnosis of Cystic Neoplasms of the Pancreas: a Review.

J Gastrointest Surg 2020 05 3;24(5):1201-1214. Epub 2020 Mar 3.

Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.

Background: The prevalence of incidental pancreatic cystic neoplasms (PCNs) has increased dramatically with advancements in cross-sectional imaging. Diagnostic imaging is limited in differentiating between benign and malignant PCNs. The aim of this review is to provide an overview of biomarkers that can be used to distinguish PCNs. Read More

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Pancreatic solid serous cystadenoma: a rare entity that can lead to a futile surgery.

J Surg Case Rep 2019 Dec 17;2019(12):rjz360. Epub 2019 Dec 17.

CHR Val de Sambre, Auvelais, Belgium.

Although many types of pancreatic tumors exist, pancreatic solid serous cystadenoma stand as the most rare. Despite advances in medical imaging, definitive diagnosis remains complex. Here, we report a case of a 63-year-old man with a suspicious lesion of the pancreas discovered during a positron emission tomography-computed tomography. Read More

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December 2019

Solid serous cystadenoma of the pancreas - Difficult assessment by EUS-FNA/FNB?

Gastroenterol Hepatol 2020 Apr 2;43(4):203-204. Epub 2020 Jan 2.

Gastroenterology Department, Hospital da Luz, Lisbon, Portugal.

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Differential diagnosis of pancreatic serous cystadenoma and mucinous cystadenoma: utility of textural features in combination with morphological characteristics.

BMC Cancer 2019 Dec 16;19(1):1223. Epub 2019 Dec 16.

Department of Biotherapy, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, No. 37 GuoXue Alley, Chengdu, 610041, People's Republic of China.

Background: Texture analysis of medical images has been reported to be a reliable method for differential diagnosis of neoplasms. This study was to investigate the performance of textural features and the combined performance of textural features and morphological characteristics in the differential diagnosis of pancreatic serous and mucinous cystadenomas.

Methods: We retrospectively reviewed 59 patients with pancreatic serous cystadenoma and 32 patients with pancreatic mucinous cystadenoma at our hospital. Read More

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December 2019

Diagnosis of Pancreatic Cystic Lesions by Virtual Slicing: Comparison of Diagnostic Potential of Needle-Based Confocal Laser Endomicroscopy versus Endoscopic Ultrasound-Guided Fine-Needle Aspiration.

J Pathol Inform 2019 13;10:34. Epub 2019 Nov 13.

Department of Pathology, The Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.

Background: Pancreatic cystic lesions are often challenging entities for diagnosis and management. EUS-FNA diagnostic accuracy is limited by paucicellularity of cytology specimens and sampling errors. Needle-based confocal laser endomicroscopy (nCLE) provides real-time imaging of the microscopic structure of the cystic lesion and could result in a more accurate diagnosis. Read More

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November 2019

EUS-FNA diagnosis of pancreatic serous cystadenoma with the aid of cell blocks and α-inhibin immunochemistry: A case series.

Diagn Cytopathol 2020 Mar 29;48(3):239-243. Epub 2019 Nov 29.

School of Medicine, European University Cyprus, Nicosia, Cyprus.

Serous cystadenoma (SCA) is an uncommon benign pancreatic neoplasm that is most often managed conservatively with follow-up rather than surgical excision. Therefore, to avoid the serious complications of pancreatic surgery, SCA should be diagnosed accurately at the preoperative level. Preoperative SCA diagnosis requires a multimodal diagnostic approach that includes imaging, cystic fluid biochemical analysis and/or endoscopic ultrasound fine-needle aspiration (EUS-FNA). Read More

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Preoperative contrast-enhanced computed tomographic characterisation of pancreatic cystic lesions: A prospective study.

SA J Radiol 2019 10;23(1):1727. Epub 2019 Jun 10.

Department of Radiodiagnosis, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, India.

Background: Characterisation of pancreatic cystic lesions has a direct role in their management and computed tomography is the mainstay of investigation for diagnosing and characterising them.

Objectives: The aim of this study was to prospectively assess the diagnostic accuracy of contrast-enhanced computed tomography (CECT) in preoperative characterisation of pancreatic cystic lesions with histopathology as the reference standard.

Method: A total of 38 patients with cystic pancreatic lesions diagnosed after clinical, laboratory and sonographic evaluation, irrespective of age, were preoperatively evaluated with CECT. Read More

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Metachronous Pancreatic Ductal Adenocarcinoma with Adjacent Serous Cystadenoma that Was Preoperatively Diagnosed by EUS-FNA: A Case Report and Review of the Literature.

Intern Med 2020 Mar 18;59(5):649-656. Epub 2019 Nov 18.

Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan.

Pancreatic serous cystic neoplasms (SCNs), such as serous cystadenoma (SCA), are generally recognized as benign because malignant counterparts of SCNs have been extremely rare. In clinical practice, pancreatic cystic neoplasms diagnosed as SCNs have been managed by conservative observation, as long as the patients remained asymptomatic. We herein report a case of metachronous ductal adenocarcinoma that was discovered during long-term follow-up of SCN and review the related literature. Read More

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Comparative analysis of hypervascular microcystic serous cystadenoma with MRI and immunohistochemistry.

Burcu Erkan

Ann Ital Chir 2019 Oct 10;8. Epub 2019 Oct 10.

Purpose: Cystic tumors of the pancreas are increasingly common lesions. Unlike mucinous cystic tumors, serous cystadenomas are benign lesions and do not pose a risk of cancer. Often seen in women in the 6th and 8th decades, they are rarely seen in younger women or in male patients. Read More

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October 2019

The Cause of Melena in a Female with Von Hippel-Lindau Disease.

Gastroenterology 2020 03 24;158(4):e6-e8. Epub 2019 Sep 24.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.

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