415 results match your criteria Pancreatic Serous Cystadenoma Imaging


Tumor growth rate of pancreatic serous cystadenomas: Endosonographic follow-up with volume measurement to predict cyst enlargement.

Pancreatology 2019 Jan 23;19(1):122-126. Epub 2018 Nov 23.

Gastroclinica WGO Training Center, Tibás, San José, Costa Rica.

Background: Serous cystadenomas are benign lesions of the pancreas. Usually they are diagnosed incidentally on cross-sectional imaging studies. Endosonography is a valuable tool in the diagnosis and follow-up of these cystic lesions. Read More

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http://dx.doi.org/10.1016/j.pan.2018.11.007DOI Listing
January 2019
1 Read

Cystic Pancreatic Tumors.

Magn Reson Imaging Clin N Am 2018 Aug;26(3):405-420

Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.

Cystic pancreatic lesions are common and often incidentally detected on cross-sectional examinations of the abdomen. Most lesions are asymptomatic and benign. However, some carry a significant risk of malignant degeneration, so correct identification, complete characterization, and adequate follow-up/management of these lesions are paramount. Read More

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http://dx.doi.org/10.1016/j.mric.2018.03.006DOI Listing
August 2018
5 Reads

Genetics of Pancreatic Neoplasms and Role of Screening.

Magn Reson Imaging Clin N Am 2018 Aug 8;26(3):375-389. Epub 2018 Jun 8.

Department of Radiology, The University of Texas MD Anderson Cancer Center, 1400 Pressler street, Unit 1473, Houston, TX 77030, USA. Electronic address:

There is a wide spectrum of pancreatic neoplasms with characteristic genetic abnormalities, tumor pathways, and histopathology that primarily determine tumor biology, treatment response, and prognosis. Although most pancreatic tumors are sporadic, 10% of neoplasms occur in the setting of distinct hereditary syndromes. Detailed studies of these rare syndromes have allowed researchers to identify a myriad of specific genetic signatures of pancreatic tumors. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10649689183001
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http://dx.doi.org/10.1016/j.mric.2018.03.005DOI Listing
August 2018
7 Reads

Mucinous cystadenoma of pancreas with honeycombing appearance: Radiological-Pathological correlation.

Indian J Radiol Imaging 2018 Jul-Sep;28(3):327-329

Department of Radiodiagnosis, Sree Balaji Medical College and Hospital, Chromepet, Chennai, Tamil Nadu, India.

Most mucinous cystadenomas of pancreas are solitary and multilocular with a few large compartments. Serous cystadenomas usually have a polycystic or microcystic (honeycomb) pattern consisting of collection of cysts (usually >6) that range from few millimetres up to 2 cm in size. Here we present a case of mucinous cystadenoma of pancreas showing an unusual appearance of honeycombing (which has not been described so far) using imaging studies such as endoscopic ultrasound and computed tomography with histopathological confirmation of the diagnosis. Read More

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http://www.ijri.org/text.asp?2018/28/3/327/242180
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http://dx.doi.org/10.4103/ijri.IJRI_469_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176663PMC
October 2018
2 Reads

The Role of Endoscopic Ultrasound in the Diagnosis of Cystic Lesions of the Pancreas.

Visc Med 2018 Jul 8;34(3):192-196. Epub 2018 Jun 8.

Department of Gastroenterology and Pancreatology, Pôle des Maladies de l'Appareil Digestif, DHU Unity, Hôpital Beaujon, Faculté Denis Diderot, AP-HP, Clichy, France.

A precise diagnosis of the nature of pancreatic cystic neoplasm (PCN) is crucial since it determines the patients in need of rapid surgical resection as well as those who can be followed up, and, accordingly, the frequency and modalities of surveillance. Endoscopic ultrasound (EUS) and especially fine needle aspiration (FNA) are invasive methods, with specific adverse events occurring in 2.7-5%. Read More

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https://www.karger.com/Article/FullText/489242
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http://dx.doi.org/10.1159/000489242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103354PMC
July 2018
8 Reads

Radiological Workup of Cystic Neoplasms of the Pancreas.

Visc Med 2018 Jul 15;34(3):182-190. Epub 2018 Jun 15.

Department of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands.

Pancreatic cystic lesions are being detected with increasing frequency because of increased use and improved quality of cross-sectional imaging techniques. Pancreatic cystic lesions encompass non-neoplastic lesions (such as pancreatitis-related collections) and neoplastic tumors. Common cystic pancreatic neoplasms include serous cystadenomas, mucinous cystic neoplasms, intraductal papillary mucinous neoplasms, and solid pseudopapillary tumors. Read More

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https://www.karger.com/Article/FullText/489674
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http://dx.doi.org/10.1159/000489674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103340PMC
July 2018
9 Reads

[Diagnosis and treatment experience of 161 cases of pancreatic serous cystic neoplasm in single center and analysis of cause of preoperation misjudgement].

Zhonghua Wai Ke Za Zhi 2018 Aug;56(8):591-596

Department of Pancreatic Surgery, Huashan Hospital of Fudan University, Shanghai 200040, China.

To analyze the causes of preoperative miscarriage of pancreatic serous cystadenoma (SCN) and find the ways to improve it. Clinical data of 425 pancreatic cystic neoplasm patients who underwent surgical resection from January 2006 to December 2016 in Department of Pancreatic Surgery in Huashan Hospital were retrospectively analyzed.Excel database was created which covered 128 fields of 7 fields: general information of patients, preoperative blood biochemical indexes, tumor markers, surgical related data, postoperative complications, imaging findings and pathology. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5815.2018.08.008DOI Listing
August 2018
1 Read

Growth rate of serous pancreatic neoplasms in vivo: a retrospective, observational study.

Acta Radiol 2018 Jul 28:284185118787350. Epub 2018 Jul 28.

3 Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.

Background Determining the growth rate of pancreatic cystic lesions on follow-up imaging is important in managing patients with these lesions. However, the growth rates of serous pancreatic neoplasms (SPNs) have been reported to vary among studies. Purpose To determine the in vivo growth rate of SPNs. Read More

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http://dx.doi.org/10.1177/0284185118787350DOI Listing
July 2018
1 Read

New horizons in the endoscopic ultrasonography-based diagnosis of pancreatic cystic lesions.

World J Gastroenterol 2018 Jul;24(26):2853-2866

Department of Gastroenterology, Ramsay Générale de Santé Private Hospital Jean Mermoz, Lyon 69008, France.

Pancreatic cystic lesions (PCLs) are increasingly being identified because of the widespread use of high-resolution abdominal imaging. These cysts encompass a spectrum from malignant disease to benign lesions, and therefore, accurate diagnosis is crucial to determine the best management strategy, either surgical resection or surveillance. However, the current standard of diagnosis is not accurate enough due to limitations of imaging and tissue sampling techniques, which entail the risk of unnecessary burdensome surgery for benign lesions or missed opportunities of prophylactic surgery for potentially malignant PCLs. Read More

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http://dx.doi.org/10.3748/wjg.v24.i26.2853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048425PMC
July 2018
13 Reads

Surgical Treatment of a Mucinous Cystic Neoplasm in a Young Female Patient - A Case Report.

Chirurgia (Bucur) 2018 May-Jun;113(3):430-435

The major challenge in the evaluation of pancreatic cystic neoplasms is identifying lesions with malignant potential or signs of malignancy. Overall, the risk of malignancy in incidentally detected pancreatic cysts is low. Pancreatic cystic neoplasms with malignant potential are: serous cystic tumors (SCTs), mucinous cystic neoplasms (MCNs), intraductal papillary mucinous neoplasms (IPMNs) and solid pseudopapillary neoplasms (SPNs). Read More

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http://dx.doi.org/10.21614/chirurgia.113.3.430DOI Listing
September 2018
11 Reads

Incidence and reasons of pancreatic resection in patients with asymptomatic serous cystadenoma.

Pancreatology 2018 Jun 8. Epub 2018 Jun 8.

Division of General and Transplant Surgery, University of Pisa, Pisa, Italy. Electronic address:

Background/objectives: Despite diagnostic refinements, pancreatic resection (PR) is eventually performed in some patients with asymptomatic serous cystadenoma (A-SCA). The aim of this study was to define incidence and reasons of PR in A-SCA.

Methods: A retrospective analysis of a prospectively maintained database was performed for all the patients referred for pancreatic cystic lesions (PCL) between January 2005 and March 2016. Read More

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http://dx.doi.org/10.1016/j.pan.2018.06.001DOI Listing
June 2018
3 Reads

Rare pancreatic masses: a pictorial review of radiological concepts.

Clin Imaging 2018 Jul - Aug;50:314-323. Epub 2018 May 4.

São Paulo State Cancer Institute of the Medical School of the University of São Paulo, Department of Radiology, Av Dr Arnaldo 251-1SS, São Paulo, SP 01246-000, Brazil; Sirio Libanes Hospital, Rua Dona Adma Jafet, 115, 01308-050 São Paulo, Brazil.

Non-ductal pancreatic neoplasm (NPN) represents a heterogeneous group of pancreatic masses, in which diagnosis and management remain challenging due to their overall rarity. Knowledge of their radiologic features is essential for differential diagnosis and to guide clinical decisions for optimal management. The purpose of this paper was to present radiological patterns of these rare pancreatic tumors, solid or predominantly solid, with emphasis in the differential diagnosis and surgical management. Read More

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http://dx.doi.org/10.1016/j.clinimag.2018.05.004DOI Listing
October 2018
1 Read

Middle segment pancreatectomy for a solid serous cystadenoma diagnosed by MRCP and review of the literature: A case report.

Mol Clin Oncol 2018 May 26;8(5):675-682. Epub 2018 Mar 26.

Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.

Solid serous cystadenoma of the pancreas is the rarest subtype of serous cystadenoma. Cystic structures are difficult to recognize by imaging studies. In the clinical setting, it is crucial to discriminate a solid serious cystadenoma from other solid pancreatic tumors. Read More

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http://dx.doi.org/10.3892/mco.2018.1598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920357PMC
May 2018
7 Reads

[Value of Magnetic Resonance Imaging Texture Feature Analysis in the Differential Diagnosis between Pancreatic Serous Cystadenoma and Mucinous Cystadenoma].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2018 Apr;40(2):187-193

Department of Radiology,Hainan Branch of Chinese PLA General Hospital,Sanya,Hainan 572013,China.

Objective To investigate the difference of tumor textures presented on T1-weighted image(T1WI) and T2-weighted image(T2WI) between pancreatic serous cystadenoma and mucinous cystadenoma. Methods Subjects including 24 patients with serous cystadenoma and 20 patients with mucinous cystadenoma who were treated in Hainan Branch of Chinese PLA General Hospital were enrolled in this study.The texture analysis was performed on T1WI and T2WI,and the texture parameters included angular second moment,contrast,correlation,inverse difference moment(IDM),and entropy. Read More

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http://dx.doi.org/10.3881/j.issn.1000-503X.2018.02.008DOI Listing
April 2018
4 Reads

Influence of the Histopathological Features of the Lesion on the Diagnostic Yield of Fine-Needle Aspiration Cytology of Pancreatic Solid Lesions.

Acta Cytol 2018 27;62(4):259-264. Epub 2018 Apr 27.

Department of Endoscopy (Endoscopic Ultrasonography Unit), Hospital Clínico Universitario San Carlos, Madrid, Spain.

Objective: The rate of pancreatic lesions has increased in recent decades due to the widespread use of advanced imaging techniques. Nowadays, a significant proportion of cases are incidentally discovered in asymptomatic patients and cytology is an important tool for the diagnosis and multidisciplinary management of these cases.

Study Design: In this study we retrospectively review the experience with pancreatic fine-needle aspiration cytology in the last 17 years at a single large tertiary hospital in Madrid, Spain. Read More

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https://www.karger.com/Article/FullText/488383
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http://dx.doi.org/10.1159/000488383DOI Listing
August 2018
9 Reads

Synchronous Pancreatic Serous Cystic Neoplasm and Duodenal Neuroendocrine Tumor: Case Report and Review of the Literature.

Int J Surg Pathol 2018 Sep 6;26(6):551-557. Epub 2018 Apr 6.

1 Department of Pathology, Odense University Hospital, Odense, Denmark.

Simultaneous presence of pancreatic serous cystic neoplasms and neuroendocrine neoplasms is rare. We present a case with the incidental finding of a duodenal neuroendocrine tumor (NET) with 2 lymph node metastases in a Whipple resection specimen performed to remove a pancreatic cystic neoplasm that postoperatively turned out to represent a serous cystic neoplasm (SCN). The patient was a 75-year-old female. Read More

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http://journals.sagepub.com/doi/10.1177/1066896918766245
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http://dx.doi.org/10.1177/1066896918766245DOI Listing
September 2018
9 Reads

Serous Cystic Neoplasms of the Pancreas: Endoscopic Ultrasonographic Versus Computed Tomography and Magnetic Resonance Imaging Features of Surgically Removed Masses.

Ultrasound Q 2018 Sep;34(3):122-127

Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Our purpose was to assess the endoscopic ultrasonography (EUS) features of serous cystic neoplasms (SCNs) of the pancreas in determining the surgical removal compared with computed tomography (CT) and magnetic resonance imaging (MRI) features. For 33 consecutive patients with 34 surgically confirmed SCNs over the past 11 years, preoperative EUS features were compared with those of CT and MRI (CT&MRI). Besides the lesion size and location, a retrospective analysis of the various imaging features was performed by 2 observers to understand the characteristics that determine the need for surgical intervention in terms of multiplicity of locules, calcification, mural thickening, mural nodules, ductal communication, and main pancreatic duct dilatation in addition to the gross morphologic type: microcystic, macrocystic (>1 cm), mixed, or solid. Read More

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http://dx.doi.org/10.1097/RUQ.0000000000000346DOI Listing
September 2018
10 Reads

Two-stage resection of a bilateral pheochromocytoma and pancreatic neuroendocrine tumor in a patient with von Hippel-Lindau disease: A case report.

Int J Surg Case Rep 2018 16;44:139-142. Epub 2018 Feb 16.

Department of Surgery, Keio University School of Medicine, Tokyo, Japan.

Introduction: von Hippel-Lindau disease (vHL disease) is a hereditary disease in which tumors and cysts develop in many organs, in association with central nervous system hemangioblastomas, pheochromocytomas, and pancreatic tumors. We herein report a case of vHL disease (type 2A) associated with bilateral pheochromocytomas, pancreatic neuroendocrine tumors (PNET), and cerebellar hemangioblastomas treated via pancreatectomy after adrenalectomy.

Case Presentation: A 51-year-old woman presented with a cerebellar tumor, bilateral hypernephroma, and pancreatic tumor detected during a medical checkup. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910515PMC
February 2018
13 Reads

Inspissated cyst fluid in endoscopic ultrasound-guided fine needle aspiration of pancreatic cysts.

Diagn Cytopathol 2018 May 24;46(5):395-399. Epub 2018 Feb 24.

Division of Cytopathology, James Homer Wright Pathology Laboratories, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Background: Inspissated cyst fluid may be identified on pancreatic cyst aspiration cytology. We report on the cytomorphologic characteristics of inspissated cyst fluid on EUS-FNA of pancreatic cysts and correlate this finding with histopathology or multimodal (cytology, cyst fluid analysis, molecular pathology, imaging) classification of cyst type.

Methods: The department archives were searched for pancreatic cyst fine-needle aspiration biopsies that contained dessicated, crystalline or inspissated material on cytologic preparations. Read More

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http://dx.doi.org/10.1002/dc.23912DOI Listing
May 2018
1 Read

[Simple mucinous cyst of the pancreas: Case-report and literature review].

Ann Pathol 2018 Apr 4;38(2):137-142. Epub 2018 Feb 4.

Service d'anatomie et cytologie pathologiques, hôpital Saint-Antoine, 184, rue du Faubourg-Saint-Antoine, 75571 Paris cedex 12, France. Electronic address:

Simple mucinous cyst of the pancreas is an unusual pancreatic cyst, first described by Kosmahl et al. in 2002 with 5 cases. We describe a case of simple mucinous cyst of the pancreas, followed by a literature review. Read More

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http://dx.doi.org/10.1016/j.annpat.2017.12.004DOI Listing

Current concepts in molecular genetics and management guidelines for pancreatic cystic neoplasms: an essential update for radiologists.

Abdom Radiol (NY) 2018 Sep;43(9):2351-2368

Department of Radiology, University of Pittsburgh Medical Center, Radiology Suite 200 East Wing E2051B, 200 Lothrop Street, Pittsburgh, PA, 15213, USA.

Cystic neoplasms in the pancreas are encountered frequently on imaging, often detected incidentally during evaluation for other conditions. They can have a variety of clinical and imaging presentations, and similarly, wide-ranging prognostic and treatment implications. In the majority, imaging helps in diagnosis of pancreatic cystic neoplasms (PCNs) and guides management decisions. Read More

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http://dx.doi.org/10.1007/s00261-017-1452-5DOI Listing
September 2018
8 Reads

Prevalence and outcomes of pancreatic cystic neoplasms in liver transplant recipients.

World J Gastroenterol 2017 Dec;23(48):8526-8532

AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia

Aim: To determine the prevalence, characteristics and clinical course of pancreatic cystic neoplasms (PCNs) in liver transplantation (LT) recipients.

Methods: We retrospectively studied consecutive patients who underwent LT between January 1998 to April 2016. Clinical and laboratory data were obtained from patient medical records. Read More

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http://www.wjgnet.com/1007-9327/full/v23/i48/8526.htm
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http://dx.doi.org/10.3748/wjg.v23.i48.8526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752712PMC
December 2017
10 Reads

Surgery of the pancreatic cystic echinococcosis: systematic review.

Transl Gastroenterol Hepatol 2017 8;2:105. Epub 2017 Dec 8.

Medical School of Tunis, University of Tunis El Manar, Tunis, Tunisia.

The prevalence of pancreatic cystic echinococcosis (PCE) in the world is low ranging between 0.2% and 0.6%. Read More

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http://dx.doi.org/10.21037/tgh.2017.11.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763016PMC
December 2017
5 Reads

New treatment of the pancreatic cystic neoplasm: Endoscopic ultrasonography-guided radiofrequency ablation combined with lauromacrogol ablation.

Turk J Gastroenterol 2018 01 30;29(1):101-104. Epub 2017 Oct 30.

Department of Gastroenterology, Chinese PLA General Hospital, Beijing, China.

Pancreatic cystic neoplasms (PCNs) are being increasingly detected because of rapid advances in radiologic technology and an increased imaging demand. The management of PCNs is challenging as most of these neoplasms are asymptomatic, but have malignant potential, and surgical resection has substantial perioperative morbidity and mortality. Endoscopic ultrasonography (EUS)-guided ablation, as a minimally invasive treatment, has received increasing attention in the past few years. Read More

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http://dx.doi.org/10.5152/tjg.2017.17340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322618PMC
January 2018
5 Reads

Pancreatic solid serous cystadenoma treated by laparoscopy: Presentation of a new case report and review of the literature.

Int J Surg Case Rep 2017 23;40:97-101. Epub 2017 Sep 23.

Department of Surgery «C», Ibn Sina Hospital, Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Morocco. Electronic address:

Solid serous cystadenoma is an uncommon benign pancreatic tumor, with only, including this case, 21 cases published so far. It is often misdiagnosis with other malignant pancreatic tumors. Below we report a new case of a solid serous cystadenoma of the pancreas treated by laparoscopic distal pancreatectomy in 53-year-old female who presented with epigastric pain. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612173047
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http://dx.doi.org/10.1016/j.ijscr.2017.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633824PMC
September 2017
10 Reads

A case of serous cystic neoplasm with form changes on an image obtained during long-term follow-up.

Nihon Shokakibyo Gakkai Zasshi 2017;114(9):1675-1684

Department of Hepato-Biliary-Pancreatic Surgery, National Hospital Organization Fukuyama Medical Center.

A 45-year-old man presented with a 24-mm macrocystic lesion at the pancreatic head, which was detected by computed tomography (CT). During six years of follow-up, CT, MRI, and endosonographic images of the cystic lesion showed that the cystic lesion had enlarged to 42mm, with the appearance of a thick cyst wall. Since a cystic tumor could not be ruled out, surgery was performed. Read More

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http://dx.doi.org/10.11405/nisshoshi.114.1675DOI Listing
March 2018
24 Reads

Calcified pancreatic and peripancreatic neoplasms: spectrum of pathologies.

Abdom Radiol (NY) 2017 11;42(11):2686-2697

Department of Radiology, Johns Hopkins University, 601 N Caroline St, Ste 3235A, Baltimore, MD, 21287, USA.

A variety of pancreatic and peripancreatic neoplasms may contain calcifications. We present a review of common to uncommon pancreatic neoplasms that may contain calcifications to include ductal adenocarcinoma, pancreatic neuroendocrine tumors, serous cystadenomas, solid pseudopapillary tumors, intraductal papillary mucinous neoplasms, mucinous cystic neoplasms, and lymphoepithelial cysts. In addition, duodenal mucinous adenocarcinoma can present as a peripancreatic mass that may contain calcification. Read More

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http://dx.doi.org/10.1007/s00261-017-1182-8DOI Listing
November 2017
3 Reads

Clinical Profile of Pancreatic Cystic Lesions in von Hippel-Lindau Disease: A Series of 48 Patients Seen at a Tertiary Institution.

Pancreas 2017 08;46(7):948-952

From the Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

Objectives: Little is known about the association between pancreatic cystic lesions (PCLs) with von Hippel-Lindau disease (VHLD). In this study, we describe the clinical presentation, type of PCLs, and risk for malignancy in PCLs in VHLD.

Methods: Patients given a diagnosis of both VHLD and PCLs were identified from electronic medical records at Mayo Clinic, Rochester, MN, from January 1, 2000, to January 1, 2016. Read More

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http://Insights.ovid.com/crossref?an=00006676-201708000-0001
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http://dx.doi.org/10.1097/MPA.0000000000000875DOI Listing
August 2017
9 Reads

Silent Presentation of a Solid Pseudopapillary Neoplasm of the Pancreas.

Am J Case Rep 2017 Jun 12;18:656-659. Epub 2017 Jun 12.

Department of Surgery, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.

BACKGROUND Solid pseudopapillary neoplasm (SPN) is a rare tumor frequently found in the head or tail of the pancreas. It mainly presents in young women between the 2nd and 3rd decades of life. A predilection for African Americans and Asians has been observed and is rarely reported in children. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478218PMC
June 2017
17 Reads

Unusual Cause of Hematochezia.

Gastroenterology 2017 07 2;153(1):17-18. Epub 2017 Jun 2.

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1053/j.gastro.2017.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540450PMC
July 2017
1 Read

and confocal endomicroscopy of pancreatic cystic lesions: A prospective study.

World J Gastroenterol 2017 May;23(18):3338-3348

Somashekar G Krishna, Phil A Hart, Darwin L Conwell, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States.

Aim: To investigate the reproducibility of the endoscopic ultrasound (EUS) - guided needle based confocal endomicroscopy (nCLE) image patterns in an setting and compare these to surgical histopathology for characterizing pancreatic cystic lesions (PCLs).

Methods: In a prospective study evaluating EUS-nCLE for evaluation of PCLs, 10 subjects underwent an nCLE (AQ-Flex nCLE miniprobe; Cellvizio, MaunaKea, Paris, France) during EUS and probe based CLE (pCLE) of the PCL (Gastroflex ultrahigh definition probe, Cellvizio) after surgical resection. Biopsies were obtained from CLE-imaged areas for comparative histopathology. Read More

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http://dx.doi.org/10.3748/wjg.v23.i18.3338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434441PMC
May 2017
30 Reads

Pancreatic Cystic Lesions: Diagnostic, Management and Indications for Operation. Part I.

Authors:
Ferdinand Bauer

Chirurgia (Bucur) 2017 Mar-Apr;112(2):97-109

We notice an increasing frequency in the detection and evaluation of pancreatic cystic lesions (PCLs) over the last three decades. They show awide spectrum of imaging and clinical features. The diagnosis and discrimination of these lesions are very important because of the risk for concurrent or later development of malignancy. Read More

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http://dx.doi.org/10.21614/chirurgia.112.2.97DOI Listing
July 2017
8 Reads

Imaging of pancreatic cystic lesions with confocal laser endomicroscopy: an ex vivo pilot study.

Surg Endosc 2017 12 25;31(12):5119-5126. Epub 2017 Apr 25.

Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Background: The differential diagnosis of pancreatic cystic lesions (PCLs) is an increasingly common clinical challenge. Confocal laser endomicroscopy (CLE) may differentiate PCLs by imaging of the cyst wall. However, clinical experience is still limited, and better image definition and characterization of the cyst wall in a spectrum of cysts are needed. Read More

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http://dx.doi.org/10.1007/s00464-017-5577-yDOI Listing
December 2017
9 Reads

Surgical Management of Pancreatic Cysts: A Shifting Paradigm Toward Selective Resection.

Dig Dis Sci 2017 07 18;62(7):1816-1826. Epub 2017 Apr 18.

Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.

Due to the widespread use of high-quality cross-sectional imaging, pancreatic cystic neoplasms are being diagnosed with increasing frequency. Clinicians are therefore asked to counsel a growing number of patients with pancreatic cysts diagnosed incidentally at an early, asymptomatic stage. Over the last two decades, accumulating knowledge on the biologic behavior of these neoplasms along with improved diagnostics through imaging and endoscopic cyst fluid analysis have allowed for a selective therapeutic approach toward these neoplasms. Read More

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http://dx.doi.org/10.1007/s10620-017-4570-6DOI Listing
July 2017
2 Reads

Validation of full-field optical coherence tomography in distinguishing malignant and benign tissue in resected pancreatic cancer specimens.

PLoS One 2017 17;12(4):e0175862. Epub 2017 Apr 17.

Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.

Background: Pancreatic cancer is the fourth leading cause of cancer-related mortality in the United States. The minority of patients can undergo curative-intended surgical therapy due to progressive disease stage at time of diagnosis. Nonetheless, tumor involvement of surgical margins is seen in up to 70% of resections, being a strong negative prognostic factor. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0175862PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393621PMC
April 2017
22 Reads

DNA testing of pancreatic cyst fluid: is it ready for prime time?

Lancet Gastroenterol Hepatol 2017 01 10;2(1):63-72. Epub 2016 Dec 10.

Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Pancreatic cysts are a clinical quandary in both diagnosis and management. Although many cysts, such as pseudocysts and serous cystadenomas, are benign and can be monitored clinically, mucinous cysts, such as intraductal papillary mucinous neoplasms and mucinous cystic neoplasms, have the potential to progress to pancreatic cancer. Considering the poor prognosis of pancreatic cancer, the detection of a pancreatic cyst can be a source of anxiety for both the patient and physician. Read More

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http://dx.doi.org/10.1016/S2468-1253(16)30084-XDOI Listing
January 2017
5 Reads

Needle-based confocal laser endomicroscopy for the diagnosis of pancreatic cystic lesions: an international external interobserver and intraobserver study (with videos).

Gastrointest Endosc 2017 Oct 10;86(4):644-654.e2. Epub 2017 Mar 10.

Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

Background And Aims: EUS-guided needle-based confocal laser endomicroscopy (nCLE) characteristics of common types of pancreatic cystic lesions (PCLs) have been identified; however, surgical histopathology was available in a minority of cases. We sought to assess the performance characteristics of EUS nCLE for differentiating mucinous from non-mucinous PCLs in a larger series of patients with a definitive diagnosis.

Methods: Six endosonographers (nCLE experience >30 cases each) blinded to all clinical data, reviewed nCLE images of PCLs from 29 patients with surgical (n = 23) or clinical (n = 6) correlation. Read More

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http://dx.doi.org/10.1016/j.gie.2017.03.002DOI Listing
October 2017
21 Reads

Needle-Based Confocal Laser Endomicroscopy for Evaluation of Cystic Neoplasms of the Pancreas.

Dig Dis Sci 2017 05 9;62(5):1346-1353. Epub 2017 Mar 9.

Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, 3-H GI Associates, Zero Emerson Place, Blossom st., Boston, MA, 02114, USA.

Background: The accurate diagnosis of cystic neoplasms of the pancreas (CNP) with current diagnostic methods is limited. Endoscopic ultrasound (EUS)-guided needle-based confocal laser endomicroscopy (nCLE) is a new technique which can obtain images from the cyst wall during EUS-fine needle aspiration (EUS-FNA). The aim of this study was to assess the safety, feasibility, and diagnostic value of nCLE for CNP. Read More

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http://dx.doi.org/10.1007/s10620-017-4521-2DOI Listing
May 2017
5 Reads

Novel Biomarkers for Pancreatic Cysts.

Dig Dis Sci 2017 07 14;62(7):1796-1807. Epub 2017 Feb 14.

Department of Pathology, University of Pittsburgh Medical Center, UPMC Presbyterian Hospital, 200 Lothrop Street, Room A616.2, Pittsburgh, PA, 15213, USA.

With increased utilization and ongoing advancements in cross-sectional abdominal imaging, the identification of a pancreatic cyst has become a frequent finding. While many pancreatic cysts are associated with a benign clinical course, others may transform into pancreatic ductal adenocarcinoma. However, distinguishing a benign from a malignant pancreatic cyst or pancreatic cyst with malignant potential on the basis of standard clinical findings, imaging parameters and ancillary studies can be challenging. Read More

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http://dx.doi.org/10.1007/s10620-017-4491-4DOI Listing
July 2017
8 Reads

Central pancreatectomy for the treatment of a benign pancreatic lesion. Case report and literature review.

Rev Esp Enferm Dig 2017 Mar;109(3):225-228

Hospital Universitario 12 de Octubre.

We present the case of a 45 year old female patient with an incidental diagnosis of a cystic pancreatic lesion corresponding to a serous cystadenoma of 14 mm. During a 5-year follow-up (CT and MRT) the lesion tripled in size and a surgical intervention was decided upon. The lesion was thought to have a benign pathology and, in an attempt to preserve the spleen and a major portion of pancreatic tissue, a central pancreatectomy with a diversion of the remaining distal pancreas was carried out. Read More

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http://dx.doi.org/10.17235/reed.2017.4291/2016DOI Listing
March 2017
2 Reads

A Case of Serous Cystadenoma Communicating with a Stenotic Santorini's Duct and a Dilated Main Pancreatic Duct.

J Gastrointestin Liver Dis 2016 Dec;25(4):551-554

Division of Endoscopy, Shizuoka Cancer Center, Nagaizumi, Suntogun, Shizuoka, 411-8777, Japan.

A 59-year-old woman was referred for investigation of a pancreatic cystic lesion. Computed tomography revealed a well-demarcated, multilocular cyst, approximately 4 cm in size, at the pancreas head. Endoscopic ultrasonography demonstrated honeycomb-like components at the cyst margin. Read More

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http://dx.doi.org/10.15403/jgld.2014.1121.254.tsuDOI Listing
December 2016
5 Reads

Giant symptomatic pancreatic cyst mimicking a malignant tumor.

Rev Esp Enferm Dig 2016 Dec;108(12):813-815

Hepato-Bilio-Pancreatic Surgery and Transplant, Hospital Clínic Barcelona, España.

Background: Pancreatic cystic lesions found in the literature are estimated between 2.6-19.6%. Read More

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December 2016
8 Reads

Analysis of Pancreatic Cyst Fluid.

Surg Pathol Clin 2016 Dec;9(4):677-684

Division of Gastroenterology and Hepatology, The Johns Hopkins Medical Institutions, 1800 Orleans Street, Sheikh Zayed Tower, Room 7125JB3, Baltimore, MD 21287, USA. Electronic address:

Pancreatic cysts are extremely common, and are identified in between 2% to 13% on abdominal imaging studies. Most pancreatic cysts are pseudocysts, serous cystic neoplasms, mucinous cystic neoplasms, or intraductal papillary mucinous neoplasms. The management of pancreatic cysts depends on whether a cyst is benign, has malignant potential, or harbors high-grade dysplasia or invasive carcinoma. Read More

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http://dx.doi.org/10.1016/j.path.2016.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145907PMC
December 2016
1 Read

Serous Cystadenoma of the Pancreas: Potentials and Pitfalls of a Preoperative Cytopathologic Diagnosis.

Acta Cytol 2017 26;61(1):27-33. Epub 2016 Nov 26.

Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Baltimore, MD, USA.

Objectives: Pancreatic serous cystadenomas (SCAs) are benign tumors. Technological advances in imaging have led to increased recognition of asymptomatic pancreatic cysts, consequently increasing the demand for cytomorphologic evaluations of cyst fluid.

Study Design: A retrospective search through the pathology archives over an 11-year period was performed to identify SCAs from pancreatectomy specimens with a presurgical pancreatic EUS-guided fine-needle aspiration (FNA). Read More

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http://dx.doi.org/10.1159/000452471DOI Listing
February 2017
18 Reads

Longterm follow-up of small pancreatic cystic lesions in liver transplant recipients.

Liver Transpl 2017 03 8;23(3):324-329. Epub 2017 Feb 8.

Department of Radiology, University of California, Los Angeles, CA.

Incidental small pancreatic cystic lesions (PCLs) are often found on preoperative imaging in patients undergoing orthotopic liver transplantation (OLT). Although these are considered benign or of low malignant potential, the influence of immunosuppression after OLT may be of concern. The aim of this study was to observe the longterm outcome of these small PCLs in post-OLT patients. Read More

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http://dx.doi.org/10.1002/lt.24680DOI Listing
March 2017
12 Reads

Intraoperative Frozen Section Analysis of the Pancreas: A Case Report and Review of the Literature.

Case Rep Pancreat Cancer 2016 1;2(1):71-74. Epub 2016 Nov 1.

Department of Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.

Intraoperative frozen section analysis is frequently used to obtain a histological diagnosis at the time of resection and to assess resection margins. Although many surgeons perceive a clinical benefit, particularly with respect to the transected resection margins, the limitations and pitfalls of frozen section analysis have not been well documented. Here, we report a case of serous cystadenoma with background pancreatitis masquerading on frozen section as an invasive pancreatic ductal adenocarcinoma. Read More

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http://dx.doi.org/10.1089/crpc.2016.0014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319693PMC
November 2016

Serous Cystadenoma of the Pancreas Showing Uptake on 68Ga PSMA PET/CT.

Clin Nucl Med 2017 Jan;42(1):56-57

From the Department of Nuclear Medicine, Royal North Shore Hospital, New South Wales, Australia.

Ga prostate-specific membrane antigen (PSMA) PET/CT is increasingly used to evaluate extent of disease in prostate carcinoma. Several other benign and malignant pathologies have also been reported to demonstrate PSMA avidity. We present a case of serous cystadenoma of the pancreas showing focal uptake on PSMA PET/CT. Read More

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/RLU.0000000000001423DOI Listing
January 2017
8 Reads

The many faces of pancreatic serous cystadenoma: Radiologic and pathologic correlation.

Diagn Interv Imaging 2017 Mar 7;98(3):191-202. Epub 2016 Sep 7.

The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted B168, 21287 Baltimore, MD, USA.

Pancreatic serous cystadenoma can be categorized into microcystic, honeycomb, oligocystic, and solid patterns based on imaging appearance. The presence of typical computed tomography (CT) features helps to differentiate serous cystadenomas from other cystic and solid pancreatic masses. Cases with atypical features present a diagnostic challenge as they can mimic malignant neoplasms. Read More

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http://dx.doi.org/10.1016/j.diii.2016.08.005DOI Listing
March 2017
2 Reads

Giant Serous Cystadenoma of the Pancreas (⩾10 cm): The Clinical Features and CT Findings.

Gastroenterol Res Pract 2016 16;2016:8454823. Epub 2016 Aug 16.

Department of Hepatobiliary Pancreatic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Xi Road, Guangzhou, Guangdong 510120, China.

Purpose. To report the clinical features and CT manifestations of giant pancreatic serous cystadenoma (≥10 cm). Methods. Read More

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http://dx.doi.org/10.1155/2016/8454823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004016PMC
September 2016
2 Reads

Obstructive Jaundice as a Complication of Macrocystic Serous Cystadenoma of the Pancreas.

Acta Med Indones 2016 Apr;48(2):129-33

Department of Internal Medicine, Faculty of Medicine, University of Udayana - Sanglah Hospital, Denpasar, Bali, Indonesia.

Macrocystic serous cystadenoma is an unusual and essentially benign pancreatic tumor. Herein, we report on a 40-year-old woman diagnosed with macrocystic serous cystadenoma who presented with obstructive jaundice. A cystic lesion in the head and body of the pancreas was revealed by abdominal computed tomography. Read More

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April 2016
2 Reads