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Case Rep Gastroenterol 2018 May-Aug;12(2):217-223. Epub 2018 May 31.

GI Department, The Brooklyn Hospital Center, Affiliate of the Mount Sinai Hospital, Brooklyn, New York, USA.

Acute pancreatitis (AP) is an inflammatory disease presenting from mild localized inflammation to severe infected necrotic pancreatic tissue. In the literature, there are a few cases of hypothermia-induced AP. However, the association between hypothermia and AP is still a myth. Read More

Khirurgiia (Mosk) 2018 (4):4-16

Vishnevsky Institute of surgeru of Healthcare Ministry of the Russian Federation, Moscow, Russia.

Aim: To evaluate an effectiveness of endovascular techniques in pancreatic surgery.

Material And Methods: For the period 1995-2017 at Vishnevsky Institute of Surgery endovascular treatment (EVT) was applied in 51 patients with chronic pancreatitis complicated by false aneurysms (FA) and postoperative hemorrhage after pancreatectomy. Various methods of embolization and stenting were used in 24 and 11 cases respectively in order to exclude FA of celiac trunk and superior mesenteric artery from blood flow. Read More

Gastrointest Endosc Clin N Am 2018 Apr;28(2):157-169

Medico-Surgical Digestive Oncology, Paoli-Calmettes Institute, 232 Boulevard de Sainte-Marguerite, Marseille 13009, France. Electronic address:

Ultrasound-guided drainage is the first-line modality for drainage of symptomatic of pancreatic fluid collections. In the context of pancreatic cancer, use of multiple double-pigtail plastic stents suffice, with high treatment efficacy. This approach provides similar success rates with low complications and better quality of life compared with surgery. Read More

Ann Ital Chir 2017 ;88:539-545

Introduction: Despite technological advancement, high grade pancreatic injuries following blunt abdominal trauma continues to remain a disease that is associated with high morbidity and mortality rates, particularly in cases of delayed diagnosis. The aim of this paper was the presentation of delayed diagnosis and treatment peculiarities of high grade pancreatic trauma and a review of literature.

Case Report: A 55-years old man, involved in motor vehicle crashes, was referred to our level I trauma center. Read More

Abdom Radiol (NY) 2018 Feb;43(2):476-488

Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

Pancreatic ductal adenocarcinoma is one of the leading causes of cancer-related deaths. With surgical resection being the only definitive treatment, improvements in technique has led to an increase in number of candidates undergoing resection by inclusion of borderline resectable disease patients to the clearly resectable group. Post-operative complications associated with pancreaticoduodenectomy and distal pancreatectomy include delayed gastric emptying, anastomotic failures, fistula formation, strictures, abscess, infarction, etc. Read More

Oncotarget 2017 Aug 16;8(33):55593-55599. Epub 2017 Mar 16.

Department of Interventional Radiology, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China.

Objective: To investigate the efficacy and safety of transarterial embolization (TAE) using embolization microspheres in the treatment of non-hypervascular malignant liver tumors.

Methods: Patients with malignant non-hypervascular liver tumors, who were treated with TAE using embolization microspheres, were selected and analyzed retrospectively. The technical success rate, tumor response, and complications were assessed. Read More

Pancreas 2017 Sep;46(8):1039-1045

From the *Medizinische Klinik 1, Universitätsklinikum Frankfurt, Goethe-Universität; †Institut für diagnostische und interventionelle Radiologie, Goethe-Universität, Frankfurt/Main; ‡Zentrum 4, Institut für Radiologie, Alb-Fils Kliniken, Göppingen; and §Gastroenterologie, Robert-Bosch-Krankenhaus, Stuttgart, Germany.

Objectives: Choosing the best treatment option at the optimal point of time for patients with walled-off necrosis (WON) is crucial. We aimed to identify imaging parameters and clinical findings predicting the need of necrosectomy in patients with WON.

Methods: All patients with endoscopically diagnosed WON and pseudocyst were retrospectively identified. Read More

Gastroenterol Res Pract 2017 23;2017:6757805. Epub 2017 Feb 23.

Department of Gastroenterology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.

Hyperlipidemic acute pancreatitis (HLAP) is characterized by critical condition and high recurrence rate compared with non-HLAP. We conducted this study to investigate the value of body mass index and waist-hip ratio in predicting severity and local complications in HLAP. 96 patients with HLAP were categorized by body mass index and waist-hip ratio, respectively. Read More

S Afr J Surg 2016 Sep;54(3):23-28

Department of Surgery and Department of Radiology; University of Cape Town Health Sciences Faculty, Groote Schuur Hospital and Netcare University of Cape Town Private Academic Hospital.

Background: Bleeding after a major pancreatic resection, although uncommon, has serious implications and substantial mortality rates.

Aim: To analyse our experience with severe post-pancreatoduodenectomy haemorrhage (PPH) over the last 7 years to establish the incidence, causes, intervention required and outcome.

Method: All patients who underwent a pancreatoduodenectomy (PD) between January 2008 and December 2015 were identified from a prospectively maintained database. Read More

Arch Iran Med 2017 Feb;20(2):124-127

Researcher Associate of Clinical Research Development Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Acute pancreatitis is characterized by activation of digestive enzymes inside the pancreas. In severe pancreatitis, necrosis of pancreas and surrounding tissues may occur. Acute necrotizing pancreatitis commonly presents as pancreatic abscess occasionally with systemic complications. Read More

ACG Case Rep J 2016 Aug 28;3(4):e136. Epub 2016 Sep 28.

Kaiser Permanente Medical Center, San Francisco, CA.

Acute obstructive suppurative pancreatic ductitis (AOSPD) is a rare clinical entity defined as suppuration from the pancreatic duct without concomitant pancreatic cyst, abscess, or necrosis. We describe a case of AOSPD in a woman with a past medical history of type 2 diabetes and chronic pancreatitis who presented with abdominal sepsis, which resolved only after therapeutic endoscopic retrograde cholangiopancreatography. Our case highlights the importance of considering AOSPD as a cause of abdominal sepsis particularly in patients with chronic pancreatitis or any recent pancreatic duct instrumentation and demonstrates that treatment requires prompt drainage and decompression of the pancreatic duct. Read More

Arq Bras Cir Dig 2016 Jul-Sep;29(3):206-210

Catholic University of Brasília, Brasília, DF, Brazil.

Introduction: : Contrast computed tomography and magnetic resonance imaging are widely used due to its image quality and ability to study pancreatic and peripancreatic morphology. The understanding of the various subtypes of the disease and identification of possible complications requires a familiarity with the terminology, which allows effective communication between the different members of the multidisciplinary team.

Aim:: Demonstrate the terminology and parameters to identify the different classifications and findings of the disease based on the international consensus for acute pancreatitis ( Atlanta Classification 2012). Read More

Transplant Proc 2016 May;48(4):1212-4

Division of Digestive and General Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.

Endoscopic management of acute necrotic pancreatitis and walled off necrosis is less invasive than surgical treatment and has become the 1st choice for treating pancreatic necrosis and abscess. We treated a case of acute necrotic pancreatitis and walled off necrosis after auxiliary partial orthotopic living-donor liver transplantation (APOLT). A 24-year-old woman was admitted to our university hospital for removal of the internal biliary stent, which had already been placed endoscopically for the treatment of biliary stricture after APOLT. Read More

Endoscopy 2016 10;48 Suppl 1:E204-5. Epub 2016 Jun 10.

Department of Pediatric Gastroenterology, Hofstra Northwell School of Medicine, Cohen Children's Medical Center, Northwell Health System, New Hyde Park, New York, USA.

Radiographics 2016 May-Jun;36(3):675-87

From the Department of Diagnostic Radiology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239 (B.R.F., K.K.J., G.B., F.V.C.); and Department of Radiology, University of Utah, Salt Lake City, Utah (A.M.S.).

The 2012 revised Atlanta classification is an update of the original 1992 Atlanta classification, a standardized clinical and radiologic nomenclature for acute pancreatitis and associated complications based on research advances made over the past 2 decades. Acute pancreatitis is now divided into two distinct subtypes, necrotizing pancreatitis and interstitial edematous pancreatitis (IEP), based on the presence or absence of necrosis, respectively. The revised classification system also updates confusing and sometimes inaccurate terminology that was previously used to describe pancreatic and peripancreatic collections. Read More

PLoS One 2016 28;11(4):e0153247. Epub 2016 Apr 28.

Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.

Intra-abdominal candidiasis (IAC) is poorly understood compared to candidemia. We described the clinical characteristics, microbiology, treatment and outcomes of IAC, and identified risk factors for mortality. We performed a retrospective study of adults diagnosed with IAC at our center in 2012-2013. Read More

J Gastroenterol Hepatol 2016 Sep;31(9):1546-54

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Ohashi Medical Center, Tokyo, Japan.

Walled-off necrosis (WON) is a relatively new term for encapsulated necrotic tissue after severe acute pancreatitis. Various terminologies such as pseudocyst, necroma, pancreatic abscess, and infected necrosis were previously used in the literature, resulting in confusion. The current and past terminologies must be reconciled to meaningfully interpret past data. Read More

J Gastroenterol Hepatol 2016 Sep;31(9):1555-65

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Ohashi Medical Center, Tokyo, Japan.

Walled-off necrosis (WON) is a new term for encapsulated necrotic tissue after severe acute pancreatitis. Various terminologies such as pseudocyst, necroma, pancreatic abscess, and infected necrosis were previously used in the literature, resulting in confusion. The current and past terminologies must be reconciled to meaningfully interpret past data. Read More

J Nepal Health Res Counc 2015 Sep-Dec;13(31):245-7

Southern Illinois University School of Medicine, Springfield, IL.

Pancreatic abscess usually occurs in the setting of pancreatitis especially if complicated by pseudocysts or pancreatic necrosis. On the other hand, pancreatic body and tail cancer is relatively uncommon cancer and rarely does it present as a pancreatic abscess. We describe a 50-year-old man with sepsis due to underlying pancreatic abscess, who was later diagnosed to have pancreatic tail adenocarcinoma with the help of endoscopic ultrasound guided fine needle aspiration cytology. Read More

Ter Arkh 2015 ;87(11):42-45

Infectious Diseases Clinical Hospital Two, Moscow, Russia.

Aim: To assess follow-up study results in human immunodeficiency virus (HIV)-infected patients with prior cerebral toxoplasmosis (CT).

Subject And Methods: Follow-up study results were assessed in HIV-infected patients with prior CT.

Results: The fate of only 97 out of 137 (66% of the hospitalized) patients discharged from hospital is known, as 40 convalescents have been lost to follow up. Read More

J Am Vet Med Assoc 2016 Feb;248(3):315-21

CASE DESCRIPTION A 22-year-old male gorilla (Gorilla gorilla gorilla) housed in a zoo was evaluated for signs of lethargy, head-holding, and cervical stiffness followed by development of neurologic abnormalities including signs of depression, lip droop, and tremors. CLINICAL FINDINGS Physical examination under general anesthesia revealed a tooth root abscess and suboptimal body condition. A CBC and serum biochemical analysis revealed mild anemia, neutrophilia and eosinopenia consistent with a stress leukogram, and signs consistent with dehydration. Read More

Endosc Int Open 2016 Jan 27;4(1):E102-6. Epub 2015 Nov 27.

Penn State Hershey Medical Center, Hershey, PA.

Background And Study Aims: Direct percutaneous endoscopic necrosectomy has been described as a minimally invasive intervention for the debridement of walled-off pancreatic necrosis (WOPN). In this retrospective cohort study, we aimed to confirm these findings in a US referral center and evaluate the clinical value of this modality in the treatment of pancreatic necrosis as well as other types of intra-abdominal fluid collections and necrosis.

Patients And Methods: Twelve consecutive patients with WOPN or other abdominal abscess requiring debridement and washout underwent computed tomography (CT)-guided drainage catheter placement. Read More

Pancreatology 2016 Jan-Feb;16(1):57-65. Epub 2015 Nov 11.

Department of Pancreatic Surgery, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, Sichuan province, 610041, China. Electronic address:

Introduction: Extrapancreatic necrosis (EPN) alone, i.e., in the absence of pancreatic parenchyma necrosis has gradually come to be regarded as a separate entity of acute necrotizing pancreatitis (ANP). Read More

World J Gastroenterol 2015 Nov;21(41):11842-53

Andreas S Vilmann, Peter Vilmann, Department of Surgical Gastroenterology, Copenhagen University Hospital Herlev, 2730 Herlev, Denmark.

The revised Atlanta classification of acute pancreatitis was adopted by international consensus, and is based on actual local and systemic determinants of disease severity. The local determinant is pancreatic necrosis (sterile or infected), and the systemic determinant is organ failure. Local complications of pancreatitis can include acute peri-pancreatic fluid collection, acute necrotic collection, pseudocyst formation, and walled-off necrosis. Read More

Dan Med J 2015 Sep;62(9)

Kirurgisk Afdeling A, Sdr. Boulevard 29, Odense Universitetshospital, 5000 Odense C, Denmark.

Introduction: The aim of this study was to report our results with open transgastric necrosectomy for walled-off necrosis in acute pancreatitis over a period of ten years.

Methods: Patients operated at the department from 2003 until 2012 were studied retrospectively.

Results: A total of 50 patients had surgery. Read More

World J Gastrointest Endosc 2015 Jun;7(6):628-42

Vishal Sharma, Surinder S Rana, Deepak K Bhasin, Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India.

Endoscopic ultrasound (EUS) has emerged as an important diagnostic and therapeutic modality in the field of gastrointestinal endoscopy. EUS provides access to many organs and lesions which are in proximity to the gastrointestinal tract and thus giving an opportunity to target them for therapeutic and diagnostic purposes. This modality also provides a real time opportunity to target the required area while avoiding adjacent vascular and other structures. Read More

Am Surg 2015 May;81(5):483-91

Department of Surgery, Konstantopouleion General Hospital, Athens, Greece.

Pancreatic carcinoma is one of the commonest malignant diseases today and the majority of patients are suitable for palliative treatment only. Radiofrequency ablation (RFA) has been used extensively for the treatment of solid organ tumors but little is known on the efficacy and safety of pancreatic ablation. To further investigate the safety of pancreatic RFA, 18 pigs had RFA of the pancreas, close to superior mesenteric vein and duodenum. Read More

Case Rep Gastrointest Med 2015 17;2015:794282. Epub 2015 Mar 17.

Spokane Digestive Disease Center, Spokane, WA 99204, USA.

Context. Colonic complications associated with acute pancreatitis have a low incidence but carry an increased risk of mortality with delayed diagnosis and treatment. Pancreatic colonic fistula is most commonly associated with walled off pancreatic necrosis or abscess formation and rarely forms spontaneously. Read More

BMC Gastroenterol 2015 Feb 14;15:19. Epub 2015 Feb 14.

Department of General Surgery, Chengdu Military General Hospital, Jinniu District, Chengdu, Sichuan Province, PR China, 610083.

Background: Pancreatitis induced by hypertriglyceridemia (HTG) has gained much attention. However, very limited numbers of studies have focused on the clinical significance of TG elevation in non-HTG induced pancreatitis, such as acute biliary pancreatitis (ABP). This study aimed to study the clinical significances of triglyceride (TG) elevation in patients with ABP. Read More

Case Rep Med 2015 20;2015:919452. Epub 2015 Jan 20.

Department of Internal Medicine, Louis Stokes Cleveland VA Medical Center, Cleveland, OH 44106, USA ; Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

Acute obstructive suppurative pancreatic ductitis (AOSPD), defined as suppuration from the pancreatic duct without associated pseudocyst, abscess, or necrosis, is a rare complication of chronic pancreatitis. We present the first case of AOSPD in an asymptomatic patient with a polymicrobial infection and review the literature on this rare clinical entity. Read More

World J Gastroenterol 2014 Dec;20(45):17185-9

Gyula Farkas, László Leindler, János Márton, György Lázár, Gyula Farkas Jr, Department of Surgery, Faculty of Medicine, University of Szeged, H-6701 Szeged, Hungary.

Aim: To investigate twenty-year experience evaluated the use of the Polysorb(R) (an absorbable lactomer) staples for distal pancreatic resection.

Methods: The data on 150 patients [92 men, 58 women, mean age 52 (24-72) years] who underwent distal pancreatectomy (DP) in the last 20 years were collected prospectively from an electronic database. The diagnosis was confirmed by endoscopic retrograde cholangiopancreatography, sonography, computed tomography and/or magnetic resonance imaging. Read More

Transplant Proc 2014 Oct;46(8):2818-21

Department of General, Vascular and Transplant Surgery, Medical University of Warsaw, Poland.

Objective: Simultaneous pancreas and kidney transplantation (SPTKx) is characterized by the high rate and variability of postoperative complications, which could be a limitation of this treatment. The aim of this study was to evaluate prevalence, types, and severity of postoperative complications due to pancreas graft among the simultaneous pancreas and kidney recipients.

Methods: Postoperative complications related to transplanted pancreas among 112 SPTKx recipients were analyzed. Read More

Surg Innov 2015 Aug 14;22(4):360-5. Epub 2014 Oct 14.

The 1st Affiliated Hospital of Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.

Background: Video-assisted retroperitoneal necrosectomy is a minimally invasive surgical technique for the treatment of severe acute pancreatitis. This study evaluated the safety and feasibility of a modified single-stage video-assisted retroperitoneal necrosectomy, retroperitoneoscopic anatomical necrosectomy (REAN).

Methods: Between September 2010 and May 2012, a total of 17 patients with infected necrotizing pancreatitis underwent REAN. Read More

Gut Liver 2014 Jul 1;8(4):341-55. Epub 2014 Jul 1.

Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Endoscopic drainage for pancreatic and peripancreatic fluid collections (PFCs) has been increasingly used as a minimally invasive alternative to surgical or percutaneous drainage. Recently, endoscopic ultrasound-guided transluminal drainage (EUS-TD) has become the standard of care and a safe procedure for nonsurgical PFC treatment. EUS-TD ensures a safe puncture, avoiding intervening blood vessels. Read More

Vestn Khir Im I I Grek 2014 ;173(1):81-3

The article presents a low-invasive method in the intraoperative ultrasound-guided surgery. The method had several steps: an access (2-3 cm) was made to a liquid formation with the following aspiration of contents, a necrotic detritus was removed through the wound tract using simultaneous ultrasound examination of efficacy of emptying the cavity with drainage. This means allowed the performance of single-stage sanitization and drainage of cavity formations, which contained the liquid and dense necrotic tissues in the lumen. Read More

Rozhl Chir 2014 Apr;93(4):216-9

In this case report, we describe the case of a 30-year-old obese patient with severe acute pancreatitis complicated during hospitalization by the development of infected necrosis, a pseudocyst and an abscess. We demonstrate a possible solution to these complications using a combination of minimally invasive approaches. The contribution of this case report resides in that it presents a combination of the percutaneous approach and the endosonographic approach in the treatment of pancreatic necrosis. Read More

J Robot Surg 2014 Jun 10;8(2):181-4. Epub 2013 Aug 10.

Department of Surgery, College of Medicine, University of Arizona, 1501 N. Campbell Ave, PO Box 245066, Tucson, AZ, 85724, USA.

Pancreatic pseudocysts are generally treated by endoscopic cystogastrostomy. However, difficult cases involving abscess, necrosis, or risk of hemorrhage often require surgical intervention. Here, we report a case of a robotically assisted cystogastrostomy. Read More

J Med Life 2013 25;6(4):486-90. Epub 2013 Dec 25.

"Carol Davila" University of Medicine and Pharmacy Department of Surgery, University Emergency Hospital Bucharest, Romania.

Unlabelled: Surgical therapy in severe acute pancreatitis significantly evolved in the last 10 to 20 years. The aim was to present the experience of the First Surgery Clinic within the University Emergency Hospital Bucharest, in the management of severe acute pancreatitis, following major etiopathogenic, diagnostic and treatment aspects. Our study was retrospective, longitudinal and descriptive, including a seven years period, between 2004 and 2010. Read More

Endosc Ultrasound 2014 Apr;3(Suppl 1):S10

Bezmailem Vakif University, Istanbul, Turkey.

Background And Aims: The endoscopic treatment of pancreatic fluid collections (PFCs) has become the preferred first-line approach. Fully covered self-expandable metal stents (FCSEMS) were considered as an alternative to multiple double pigtail stents. The aim of this study was to evaluate the results of the endosonography guided drainage (EUS-GD) of PFCs with FCEMS. Read More

BMJ Case Rep 2014 Jan 10;2014. Epub 2014 Jan 10.

Department of Gastroenterology, Pondicherry Institute of Medical Sciences, Pondicherry, India.

Infected walled-off necrosis (WON), previously referred to by various terminologies including pancreatic abscess, is one of the well-known local complications of acute necrotising pancreatitis. Very rarely they can spontaneously rupture or fistulise into adjacent structures, leading to either further complications or resolution. More often these events lead to complications rather than resolution of the condition. Read More

Semin Intervent Radiol 2012 Dec;29(4):314-8

Department of Radiology, University of Chicago, Chicago, Illinois.

Pancreatic fluid collections include a wide range of entities such as cystic neoplasms, both benign and malignant; vascular pathology such as pseudoaneurysms and hematomas; and a host of other entities such as pseudocysts, seromas, abscesses, and bilomas. The distinction between these entities requires correlating an often complex and overlapping clinical presentation with findings on imaging studies, typically computed tomography, magnetic resonance imaging, and ultrasound. As complex as the diagnostic work-up may be, the treatment of pancreatic collections poses its own set of challenges and often requires a multidisciplinary collaboration among interventional radiologists, surgeons, and gastroenterologists. Read More

AJR Am J Roentgenol 2013 Dec;201(6):W877-92

1 Department of Radiological Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK.

Objective: Although pancreatitis is an uncommon entity in children, the pediatric population can develop serious and long-lasting complications, including pseudocyst, necrosis, hemorrhage, vascular thrombosis, vascular pseudoaneurysm, abscess, and pancreaticopleural fistula. CT has historically been the mainstay for noninvasive imaging of the pancreas. This modality is limited in the pediatric population because of poorly developed retroperitoneal fat planes, difficulty in evaluating the ductal anatomy, and the use of ionizing radiation. Read More

Surg Endosc 2013 Nov 13;27(11):4397-8. Epub 2013 Aug 13.

Department of General, Gastroenterological and Oncological Surgery, Medical University of Warsaw, ul. Banacha 1A, 02-097, Warsaw, Poland,

J Oral Maxillofac Surg 2014 Jan 1;72(1):83-8. Epub 2013 Aug 1.

Professor and Head, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, Chicago, IL.

Metastatic disease to the oral cavity is rare, representing only 1-8% of oral malignancies, and involvement of the mandibular condyle is even less prevalent. In a recent literature review of 796 cases of metastatic disease to the oral cavity, only 39 (13.8%) involved the condyle. Read More

Nan Fang Yi Ke Da Xue Xue Bao 2013 Jul;33(7):1083-6

Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, China.

Objective: To explore the value of (18)F-FDG PET/CT in the diagnosis of extrapulmonary tuberculosis (ET).

Methods: The imaging data from 88 cases of ET undergoing (18)F-FDG PET/CT examinations between August, 2005 and May, 2011 were analyzed retrospectively.

Results: All the 88 cases showed high (18)F-FDG uptake on PET imaging with a SUVmax ranging from 1. Read More

World J Gastroenterol 2013 Jun;19(23):3685-92

Department of Gastroenterology and Endoscopy, Fejér Megyei Szent György Teaching Hospital, H-8000 Székesfehérvár, Hungary.

Walled-off pancreatic necrosis and a pancreatic abscess are the most severe complications of acute pancreatitis. Surgery in such critically ill patients is often associated with significant morbidity and mortality within the first few weeks after the onset of symptoms. Minimal invasive approaches with high success and low mortality rates are therefore of considerable interest. Read More

Asian J Surg 2013 Oct 17;36(4):159-64. Epub 2013 Jun 17.

Department of Hepatobiliary Surgery, First Affiliated Hospital of People's Liberation Army (PLA) General Hospital, Beijing, China.

Objective: To explore the effect of retroperitoneal laparoscopic debridement and drainage on infected necrosis in severe acute pancreatitis.

Materials And Methods: This retrospective study included 18 patients with severe acute pancreatitis (SAP) undergoing retroperitoneal laparoscopic debridement and drainage from May 2006 to April 2012 in our hospital. All patients had infected retroperitoneal necrosis and single or multiple peritoneal abscesses. Read More

Surg Endosc 2013 Nov 19;27(11):4395-6. Epub 2013 Jun 19.

Department of Gastroenterology, University Clinical Center Tuzla, Trnovac bb, 75000, Tuzla, Bosnia and Herzegovina,

Dig Endosc 2014 May 7;26(3):474-7. Epub 2013 Jun 7.

Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka.

Endoscopic necrosectomy (EN) for walled-off pancreatic necrosis (WOPN) is less invasive than surgical treatment and has become the first choice for pancreatic abscess. EN is usually carried out with several devices including snares, baskets, and grasping forceps. Occasionally, we have encountered cases in which EN has not been satisfactorily carried out, and there is pressure for further innovation in EN. Read More

J Surg Res 2013 Aug 3;183(2):592-7. Epub 2013 Jan 3.

Department of Digestive Internal Medicine, Pingxiang Hospital, Southern Medical University, Pingxiang, Jiangxi, People's Republic of China.

Background: Severe acute pancreatitis (SAP) with severe complications such as multiple organ failure, necrosis, abscess, and formation of pancreatic pseudocysts often gives rise to a high mortality despite intensive treatment. Parenteral nutrition (PN), elemental enteral nutrition, and ecoimmunonutrition (EIN) hastened the recovery of SAP patients, stimulated gastrointestinal motility, and alleviated the degree of systemic inflammatory response syndrome. This study aimed to examine the effects of enteral nutrition (EN) and EIN on bacterial translocation and cytokine production in patients with SAP. Read More