901 results match your criteria Pancreatic Divisum


Incidence and risk factors for post-ERCP pancreatitis in pancreas divisum patients without chronic pancreatitis.

Scand J Gastroenterol 2020 Jun 22:1-5. Epub 2020 Jun 22.

Digestive Endoscopy Center, Department of Gastroenterology, Changhai Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.

The studies on post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in pancreas divisum (PD) patients without chronic pancreatitis (CP) are rare. In this study, we aimed to evaluate the incidence of PEP in PD patients without CP and the risk and protective factors for PEP. Consecutive patients with symptomatic PD that underwent ERCP from January 2005 to December 2017 were retrospectively analyzed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/00365521.2020.1774922DOI Listing

Complex Pancreaticobiliary Maljunction with Pancreas Divisum and Obstructive Pseudocyst.

J Clin Imaging Sci 2020 25;10:31. Epub 2020 May 25.

Departments of Radiology, Tripler Army Medical Center, 1 Jarrett White Rd., Honolulu, Hawaii, United States.

Pancreaticobiliary maljunction (PBM) is the congenital junction of the bile and pancreatic ducts into a common channel located anatomically outside of the duodenal wall. The complex type (Type D) is the rarest type and occurs in conjunction with other pancreaticobiliary anomalies. We present a case of complex PBM with pancreas divisum presenting as acute pancreatitis and obstructive symptoms secondary to a pancreatic pseudocyst. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.25259/JCIS_17_2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294320PMC

Biliary anatomy and pancreatic duct variations: A cross-sectional study.

Saudi J Gastroenterol 2020 May 26. Epub 2020 May 26.

Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Background/aim: Biliary tree and pancreatic duct can appear in different variations whose proper understanding is obligatory for surgeons. Magnetic resonance cholangiopancreatography (MRCP) is considered a safe and accurate tool for evaluating biliary tree and pancreatic duct. Typical anatomy for right hepatic duct (RHD) and left hepatic duct (LHD) is reported as 57% and 63%, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/sjg.SJG_573_19DOI Listing

Synchronous Periampullary Tumors in a Patient With Pancreas Divisum and Neurofibromatosis Type 1.

Front Genet 2020 28;11:395. Epub 2020 Apr 28.

Laboratório de Medicina Genômica, Centro de Pesquisa Experimental, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

Introduction: In this study, we describe for the first time a Neurofibromatosis type 1 patient with pancreas divisum, multiple periampullary tumors and germline pathogenic variants in and genes.

Case Report: A 62-year-old female NF1 patient presented with weakness, choluria, nausea, and diffuse abdominal pain to an emergency room service. Magnetic resonance imaging revealed an abdominal mass involving the periampullary region and pancreas divisum. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fgene.2020.00395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212385PMC

Clinical importance of main pancreatic duct variants and possible correlation with pancreatic diseases.

Scand J Gastroenterol 2020 May 12;55(5):517-527. Epub 2020 May 12.

Department of Medicine, Huddinge, Karolinska Institute, Stockholm, Sweden.

Except for pancreas divisum (PD), the prevalence of anatomic variants of the main pancreatic duct (MPD) seems to be insufficiently investigated. To date, their role in the occurrence of pancreatic exocrine insufficiency (PEI) and morphological changes suggestive of chronic pancreatitis (CP) has remained unclear. A systematic review was performed, searching MEDLINE and Web of Science, limited to articles published between 1960 and 1 June 2019. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/00365521.2020.1760345DOI Listing

Role of magnetic resonance cholangiopancreatography (MRCP) in learning anatomical variations in pancreatic duct.

J Pak Med Assoc 2020 Mar;70(3):472-476

Department of Anatomy, United Medical & Dental College, affiliated by Jinnah Sindh Medical University, Karachi, Pakistan.

Objective: To assess the frequency of anatomical variations of pancreatic duct through magnetic resonance cholangiography pancreatography. .

Methods: The cross-sectional prospective study was conducted from May 2011 to December 2012 at the Department of Anatomy, Institute of Basic Medical Sciences (IBMS), Dow University of Health Sciences, Karachi, in collaboration with the Department of Radiology, Aga Khan University Hospital, Karachi. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5455/JPMA.15767DOI Listing

Prevalence and Factors Associated with Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis in Children.

Dig Dis Sci 2020 Mar 3. Epub 2020 Mar 3.

Department of Gastroenterology, Shanghai Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, 200120, Shanghai, China.

Background: Pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP).

Aim: To assess the prevalence and factors associated with post-ERCP pancreatitis (PEP) in a Chinese pediatric population.

Methods: Sixty-six children who underwent ERCP between March 2018 and March 2019 at Shanghai Children's Medical Center were retrospectively recruited for the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10620-020-06179-5DOI Listing

Frequency of Obliteration of the Dorsal and Ventral Ducts of the Pancreas in Islet Transplantation.

Dig Dis Sci 2020 Feb 21. Epub 2020 Feb 21.

Clinical Islet Transplant Program, University of Alberta, 210 College Plaza 8215-112 St, Edmonton, AB, T6G2C8, Canada.

Background: Islet isolation is an essential process in every human islet transplantation protocol. Intraductal enzyme delivery followed by adequate distention of the pancreas is the most critical step in islet isolation. Anomalies of the pancreatic duct system can significantly affect this process. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10620-020-06145-1DOI Listing
February 2020

Secretin Improves Visualization of Nondilated Pancreatic Ducts in Children Undergoing MRCP.

AJR Am J Roentgenol 2020 04 5;214(4):917-922. Epub 2020 Feb 5.

Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229.

The objective of our study was to assess whether secretin improves visualization of a nondilated pancreatic duct and whether it increases identification of variant duct anatomy on MRCP in pediatric patients. This study is a delayed retrospective review of MRCP images that were prospectively obtained of 50 volunteers without a history of pancreatic disease who ranged in age from 6 to 15 years old. MRCP images (coronal 3D fast recovery fast spin-echo [FSE] and coronal single-shot FSE fat-saturated sequences) obtained before and after secretin administration were separated for review by three radiologists (reviewers 1-3). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2214/AJR.19.21798DOI Listing

Mixed-type intraductal papillary mucinous neoplasm in a patient with pancreas divisum: pancreatoscopy through the Santorini duct with direct intraductal biopsy.

Gastrointest Endosc 2020 Jun 22;91(6):1398-1400. Epub 2020 Jan 22.

Gastroenterology and Endoscopy Unit, ARNAS Civico - Di Cristina, Benfratelli Hospital, Palermo, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gie.2020.01.023DOI Listing

Pancreatoscopy-directed Electrohydraulic Lithotripsy in a Pediatric Patient With Pancreas Divisum and Cystic Fibrosis.

J Pediatr Gastroenterol Nutr 2020 Feb;70(2):e48

Section of Pediatric Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Texas Children's Hospital.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPG.0000000000002347DOI Listing
February 2020

Intraductal papillary mucinous neoplasm of the pancreas associated with pancreas divisum resulting in a "fish-eye" minor papilla.

Gastrointest Endosc 2020 Jun 7;91(6):1396-1397. Epub 2020 Jan 7.

Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gie.2020.01.005DOI Listing

Genetic Evaluation of Children with Idiopathic Recurrent Acute Pancreatitis.

Dig Dis Sci 2020 Jan 3. Epub 2020 Jan 3.

Asian Institute of Gastroenterology, 6-3-661, Hyderabad, 500082, India.

Objectives: Several genetic risk factors have been identified in adults with idiopathic acute recurrent pancreatitis (IARP). However, the literature regarding the genetics of IARP is sparse in children. In this study, we aimed to analyze the genetic risk factors in children with IARP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10620-019-06026-2DOI Listing
January 2020
2.550 Impact Factor

Cystic fibrosis transmembrane conductance regulator functional evaluations in a G542X+/- IVS8Tn:T7/9 patient with acute recurrent pancreatitis.

World J Clin Cases 2019 Nov;7(22):3757-3764

Cystic Fibrosis Center, Azienda Ospedaliera Universitaria Integrata Verona, Verona 37126, Italy.

Background: Acute recurrent pancreatitis (ARP) is characterized by episodes of acute pancreatitis in an otherwise normal gland. When no cause of ARP is identifiable, the diagnosis of "idiopathic" ARP is given. Mutations in the cystic fibrosis transmembrane conductance regulator () gene increase the risk of ARP by 3- to 4-times compared to the general population, while cystic fibrosis (CF) patients present with a 40- to 80-times higher risk of developing pancreatitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12998/wjcc.v7.i22.3757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887611PMC
November 2019

Agenesis of the dorsal pancreas: a very rare entity causing diabetes mellitus.

Wien Med Wochenschr 2020 May 3;170(7-8):168-170. Epub 2019 Dec 3.

Department of Internal Medicine I, Division of Gastroenterology and Hepatology, Endocrinology and Rheumatology, Klinikum Wels-Grieskirchen, Grieskirchnerstraße 42, 4600, Wels, Austria.

Dorsal pancreatic agenesis is a very rare pancreatic developmental anomaly resulting in missing corpus and cauda of the pancreas. Due to improvements and more widespread use of advanced radiological techniques like CT or MRI, the possibility of finding this disorder is growing. Thus, this rare congenital condition, as well as a pancreas divisum and pseudo-agenesis secondary to chronic pancreatitis, must be considered in the differential diagnosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10354-019-00717-1DOI Listing

What should be the best approach in the management of bile duct cysts in the era of cholangioscopy?

Rev Esp Enferm Dig 2019 12;111(12):977

Instituto Ecuatoriano de Enfermedades Digestivas .

We read with great interest the scientific letter by Sánchez Melgarejo JF et al., in which they report a degenerate Todani Ia choledochal cyst in a patient with a pancreas divisum. However, patients with a choledochal cyst might benefit from per oral cholangioscopy for malignancy detection and extension evaluation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17235/reed.2019.6578/2019DOI Listing
December 2019

The Liverpool duodenum-and spleen-preserving near-total pancreatectomy can provide long-term pain relief in patients with end-stage chronic pancreatitis.

Langenbecks Arch Surg 2019 Nov 20;404(7):831-840. Epub 2019 Nov 20.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Baden-Württemberg, Germany.

Purpose: Total pancreatectomy may improve symptoms in patients with severe end-stage chronic pancreatitis. This might be achieved whilst preserving both the duodenum- and spleen-(DPSPTP). Mature clinical outcomes of this approach are presented. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00423-019-01837-3DOI Listing
November 2019

Severe acute pancreatitis following cold polypectomy of the minor duodenal papilla in a case with pancreas divisum.

Dig Endosc 2020 Jan 20;32(1):151. Epub 2019 Nov 20.

Division of Research and Development for Minimally Invasive Treatment, Cancer Center, School of Medicine, Keio University, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/den.13570DOI Listing
January 2020

Case report on Ansa Pancreatica: An Uncommon Cause Accounting for Recurrent Pancreatitis in Children.

J Pak Med Assoc 2019 Nov;69(11):1759-1761

Department of Pediatrics, Shifa College of Medicine, Shifa international Hospital, Islamabad, Pakistan.

Acute recurrent pancreatitis is a rare entity in children. It can be caused by a number of reasons, anatomical variations being one of them. Panctreatica divisum is the most common form of ductal anomaly while ansa pancreatica has been the least studied and explored. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5455/JPMA.29846.DOI Listing
November 2019

Separate pancreatic ducts draining into a type IV choledochal cyst: simultaneous anatomical variants in a child suffering from cholelithiasis and acute pancreatitis.

Surg Radiol Anat 2020 Apr 9;42(4):449-452. Epub 2019 Nov 9.

Section of Radiological Sciences, Department of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, Policlinico "G. Martino" Via Consolare Valeria 1, 98100, Messina, Italy.

The biliary tree and the pancreatic ducts originate from different buds of the primitive foregut. A plethora of anatomical variants and congenital anomalies have been described for both the biliary and the pancreatic duct systems, although they are usually asymptomatic. However, in some cases, these abnormalities can lead to serious clinical scenarios, especially when involving the biliopancreatic junction, with consequent mixing and reflux of the two different juices. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00276-019-02377-7DOI Listing

Performance Characteristics of Magnetic Resonance Imaging in Patients With Pancreas Divisum.

Pancreas 2019 Nov/Dec;48(10):1343-1347

From the Division of Digestive Diseases, Department of Medicine, Emory University school of Medicine, Atlanta, GA.

Objective: This study was designed to assess the diagnostic accuracy of standard nonsecretin-enhanced preprocedural magnetic resonance imaging/cholangiopancreatography (MRI/MRCP) in patients with and without pancreas divisum.

Methods: Patients undergoing MRI/MRCP followed by endoscopic retrograde cholangiopancreatography with between 2009 and 2016 were reviewed. The diagnostic accuracy of the MRI/MRCP was evaluated against the pancreatography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPA.0000000000001437DOI Listing
November 2019

Identification and management of pancreas divisum.

Expert Rev Gastroenterol Hepatol 2019 Nov 8;13(11):1089-1105. Epub 2019 Nov 8.

Indiana University School of Medicine, Division of Gastroenterology, Indianapolis, IN, USA.

: Pancreas divisum is the most common congenital malformation of the pancreas with the majority asymptomatic. The etiological role, pathogenesis, clinical significance and management of pancreas divisum in pancreatic disease has not been clearly defined and our understanding is yet to be fully elucidated.: This review describes the role of pancreas divisum in the development of pancreatic disease and the ambiguity related to it. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17474124.2019.1685871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872911PMC
November 2019
1 Read

Acute Pancreatitis in Pancreas Divisum Secondary to an Impacted Stone in the Minor Papilla.

Cureus 2019 Aug 25;11(8):e5481. Epub 2019 Aug 25.

Internal Medicine, Johns Hopkins Bayview Medical Center, Baltimore, USA.

Pancreas divisum is reported to occur in up to 14% of the population. The majority of patients with this congenital anomaly remain asymptomatic. Pancreas divisum can be associated with recurrent pancreatitis due to inadequate drainage of pancreatic secretions through the dorsal pancreatic duct and the minor papilla. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.5481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812940PMC
August 2019
1 Read

Pancreas divisum inversus.

Clin Anat 2020 Jul 12;33(5):646-652. Epub 2019 Oct 12.

Radiology Unit, Department of Experimental, Diagnostic and Speciality Medicine, Sant'Orsola Hospital, University of Bologna, Bologna, Italy.

Pancreatic duct variations are usually diagnosed incidentally, in particular when using magnetic resonance cholangiopancreatography (MRCP), the most accurate imaging modality for depicting the pancreatic ductal system. However, the frequency and the embryologic development of pancreatic variants have not been well investigated. The purpose of this prospective study was to investigate the frequency of pancreatic ductal variants, providing potential explanations of their embryologic basis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ca.23475DOI Listing
July 2020
2 Reads

Pancreatitis in the developmentally anomalous pancreas.

Abdom Radiol (NY) 2020 May;45(5):1316-1323

Department of Radiology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.

Developmental anomalies of the pancreas include more common entities such as pancreas divisum and annular pancreas, and unusual entities such as heterotopic pancreas. While these anomalies can present a diagnostic challenge to the radiologist, when the pancreatic tissue involved in these processes develops pancreatitis, the radiographic appearance can present a diagnostic dilemma. Awareness of these pancreatic anomalies and familiarity with their appearance when inflamed is necessary to distinguish pancreatitis in the developmentally anomalous pancreas from other inflammatory or neoplastic processes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00261-019-02197-8DOI Listing
May 2020
1 Read

Long-term outcomes of therapeutic ERCP in pediatric patients with pancreas divisum presenting with acute recurrent or chronic pancreatitis.

Pancreatology 2019 Sep 8;19(6):834-841. Epub 2019 Aug 8.

Digestive Endoscopy Center, Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. Electronic address:

Objectives: The aim of this study was to evaluate the long-term outcomes of therapeutic endoscopic retrograde cholangiopancreatography (ERCP) for pediatric patients with pancreas divisum (PD) presenting with acute recurrent pancreatitis (ARP) or chronic pancreatitis (CP).

Methods: Between May 2008 and August 2017, pediatric patients with PD who received endotherapy at Ruijin Hospital were identified and grouped according to clinical presentation, namely ARP and CP. Primary success was defined as patients' improvement in symptoms after index ERCPs, without further intervention or any analgesic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pan.2019.08.004DOI Listing
September 2019
3 Reads
2.504 Impact Factor

SpHincterotomy for Acute Recurrent Pancreatitis Randomized Trial: Rationale, Methodology, and Potential Implications.

Pancreas 2019 09;48(8):1061-1067

Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Objectives: In patients with acute recurrent pancreatitis (ARP), pancreas divisum, and no other etiologic factors, endoscopic retrograde cholangiopancreatography (ERCP) with minor papilla endoscopic sphincterotomy (miES) is often performed to enlarge the minor papillary orifice, based on limited data. The aims of this study are to describe the rationale and methodology of a sham-controlled clinical trial designed to test the hypothesis that miES reduces the risk of acute pancreatitis.

Methods: The SpHincterotomy for Acute Recurrent Pancreatitis (SHARP) trial is a multicenter, international, sham-controlled, randomized trial comparing endoscopic ultrasound + ERCP with miES versus endoscopic ultrasound + sham for the management of ARP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPA.0000000000001370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699897PMC
September 2019
9 Reads

A degenerate Todani Ia choledochal cyst in a patient with pancreas divisum.

Rev Esp Enferm Dig 2019 08;111(8):650-651

Aparato Digestivo, Hospital General Universitario Morales Meseguer.

Bile duct cysts represent congenital abnormalities associated with biliopancreatic maljunction that may undergo malignant degeneration. We report herein the case of a 72-year-old male patient with cholangitis. MR-cholangiography and abdominal CT revealed a mass at the biliary-pancreatic-duodenal crossroads, extrahepatic biliary dilation up to 38 mm, and pancreas divisum. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17235/reed.2019.6095/2018DOI Listing
August 2019
8 Reads

Practice Patterns and Use of Endoscopic Retrograde Cholangiopancreatography in the Management of Recurrent Acute Pancreatitis.

Clin Endosc 2020 Jan 5;53(1):73-81. Epub 2019 Jul 5.

Division of Digestive Disease, Department of Medicine, Emory University, Atlanta, GA, USA.

Background/aims: There are conflicting opinions regarding the management of recurrent acute pancreatitis (RAP). While some physicians recommend endoscopic retrograde cholangiopancreatography (ERCP) in this setting, others consider it to be contraindicated in patients with RAP. The aim of this study was to assess the practice patterns and clinical features influencing the management of RAP in the US. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5946/ce.2019.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003016PMC
January 2020
1 Read

Idiopathic Ileo-Ileo-Cecal Intussuception in a 25-Year-Old Female.

Am J Case Rep 2019 Jun 20;20:872-876. Epub 2019 Jun 20.

Department of Emergency, Joseph Bracops Hospital, Bruxelles, Belgium.

BACKGROUND Intussusception is defined as the penetration or telescoping of a segment of bowel into a more distal segment. Intussusception is a common cause of small bowel obstruction, especially in children. However, this finding is much less common in adults. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12659/AJCR.914110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598787PMC
June 2019
8 Reads

Treatment of Difficult Minor Papilla Cannulation in Patients of Pancreatic Divisum: Using Endoscopic Ultrasonography-guided Puncture Combined With Endoscopic Retrograde Cholangiopancreatography: 2 Cases and Literature Review.

Surg Laparosc Endosc Percutan Tech 2019 Aug;29(4):e60-e64

Department of Gastroenterology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.

Context: Pancreas divisum (PD), the most common congenital anatomic variation of the pancreatic ductal system, is still rare in clinical practice. Endoscopic retrograde cholangiopancreatography (ERCP) is the first-line treatment for patients with symptomatic PD. However, even by experienced endoscopists, the procedure of ERCP can fail in 3% to 10% of cases. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00129689-201908000-0002
Publisher Site
http://dx.doi.org/10.1097/SLE.0000000000000686DOI Listing
August 2019
5 Reads

Diagnosis and treatment of pancreas divisum: A literature review.

Hepatobiliary Pancreat Dis Int 2019 Aug 20;18(4):332-336. Epub 2019 May 20.

Division of General Surgery, Sanchinarro Hospital, San Pablo University, calle oña 10, 28050 Madrid, Spain.

Background: Pancreas divisum is a congenital embryological disease caused by a lack of fusion between the ventral and dorsal pancreatic ducts in the early stages of embryogenesis. Recurrent acute pancreatitis, chronic pancreatitis or chronic abdominal pain are the main clinical syndromes at presentation and occur in only 5% of the patients with pancreas divisum. This review aimed to discuss diagnosis and treatment strategies in patients with symptomatic pancreas divisum. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hbpd.2019.05.004DOI Listing
August 2019
17 Reads

Rare variant of pancreaticobiliary maljunction associated with pancreas divisum in a child diagnosed and treated by endoscopic retrograde cholangiopancreatography: A case report.

World J Clin Cases 2019 May;7(9):1073-1079

Department of Gastroenterology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China.

Background: Pancreaticobiliary maljunction (PBM) is an uncommon congenital anomaly of the pancreatic and biliary ductal system, defined as a union of the pancreatic and biliary ducts located outside the duodenal wall. According to the Komi classification of PBM, the common bile duct (CBD) directly fuses with the ventral pancreatic duct in all types. Pancreas divisum (PD) occurs when the ventral and dorsal ducts of the embryonic pancreas fail to fuse during the second month of fetal development. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12998/wjcc.v7.i9.1073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511932PMC
May 2019
6 Reads

Is MRCP necessary to diagnose pancreas divisum?

BMC Med Imaging 2019 04 29;19(1):33. Epub 2019 Apr 29.

Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, INF 110, 69120, Heidelberg, Germany.

Background: The purpose of this study is to compare the performance of three-dimensional magnetic resonance cholangiopancreatography (3D-MRCP) with non-MRCP T2-weighted magnetic resonance imaging (MRI) sequences for diagnosis of pancreas divisum (PD).

Methods: This is a retrospective study of 342 consecutive patients with abdominal MRI including 3D-MRCP. 3D-MRCP was a coronal respiration-navigated T2-weighted sequence with 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12880-019-0329-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489286PMC
April 2019
11 Reads

[Pancreatic Mass or Cyst? Diagnostic Dilemma].

Dig Dis 2019 8;37(6):521-524. Epub 2019 Apr 8.

Division of Gastroenterology and Hepatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

A santorinicele is a rare anomaly defined as focal cystic dilation of the terminal portion of the dorsal pancreatic duct at the minor papilla. Importantly this anomaly has been suggested as a possible cause of relative stenosis of the minor papilla. This anomaly has been associated with pancreatic divisum and recurrent acute pancreatitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000497448DOI Listing
December 2019
19 Reads

Association between chronic asymptomatic pancreatic hyperenzymemia and pancreatic ductal anomalies: a magnetic resonance cholangiopancreatography study.

Abdom Radiol (NY) 2019 07;44(7):2494-2500

Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Purpose: Elucidating the association between pancreatic ductal anomalies and chronic asymptomatic pancreatic hyperenzymemia using magnetic resonance cholangiopancreatography.

Methods: We conducted a single-center, retrospective, case-control study. The healthy community group comprised 554 subjects who participated in a paid, whole-body health checkup program. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00261-019-02004-4DOI Listing
July 2019
13 Reads

Identifying Factors Predicting Response to Endoscopic Management of Chronic Pancreatitis Secondary to Pancreas Divisum.

J Gastrointest Surg 2020 Mar 18;24(3):585-589. Epub 2019 Mar 18.

Department of Surgery, University of Louisville, Louisville, KY, USA.

Introduction: Appropriately selecting patients with chronic pancreatitis associated with pancreas divisum (PD) for endoscopic retrograde cholangiopancreatography (ERCP)-based therapy versus surgery remains difficult. The objective of this study was to identify factors that predict success or failure of ERCP for treatment of chronic pancreatitis in PD.

Methods: Patients undergoing ERCP for a diagnosis of PD and pancreatitis between 2008 and 2016 were identified and grouped according to whether they required one or two ERCPs or three or more ERCPs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11605-019-04122-2DOI Listing
March 2020
8 Reads

Pancreas divisum and recurrent pancreatitis: long-term results of minor papilla sphincterotomy.

Scand J Gastroenterol 2019 Mar 17;54(3):359-364. Epub 2019 Mar 17.

a Digestive Endoscopy Unit, Policlinico Agostino Gemelli Foundation IRCCS , Rome , Italy.

Pancreas divisum (PD) is the most common congenital variant of the pancreatic ductal system and a potential cause of acute recurrent pancreatitis (ARP). Endoscopic therapy is a therapeutic option for symptomatic PD, but there is limited data on long-term results. We aimed to assess the effect of minor papilla endoscopic sphincterotomy (MiES) in the setting of ARP in patients with PD. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/00365521.2019.1
Publisher Site
http://dx.doi.org/10.1080/00365521.2019.1584640DOI Listing
March 2019
10 Reads

Intraductal papillary mucinous neoplasm of the main duct in a patient with pancreas divisum.

Rev Esp Enferm Dig 2019 Apr;111(4):322

Cirugía General, Complejo Hospitalario de Navarra.

Pancreas divisum is a congenital anomaly present in 5-10% of the population and is usually asymptomatic. Pancreatic intraductal papillary mucinous neoplasms (IPMN) are mucinous cystic tumors that have malignant potential and are classified according to their location as IPMN of the main duct, branch duct or mixed type. Larger lesions and those originating in the main duct have an increased risk of malignancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17235/reed.2019.5959/2018DOI Listing
April 2019
9 Reads

Anterograde Endoscopic Ultrasound-Guided Pancreatic Duct Drainage: A Technical Review.

Dig Dis Sci 2019 07 7;64(7):1770-1781. Epub 2019 Feb 7.

Section of Digestive Diseases, West Virginia University Medicine, PO Box 9161, One Medical Center Drive, Morgantown, WV, 26506-9161, USA.

The advancement of pancreatic endotherapy has increased the availability of minimally invasive endoscopic pancreatic ductal drainage techniques. In this regard, familiarity with endoscopic ultrasound-guided pancreatic duct drainage (EUS-PDD) is critical for treatment of obstructed pancreatic ductal systems, especially in nonsurgical candidates and in patients desiring a minimally invasive approach. Two distinct forms of EUS-PDD exist, viz. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10620-019-05495-9DOI Listing
July 2019
10 Reads

The Utility of Endoscopic Ultrasound in Patients with Isolated Elevations in Serum Amylase and/or Lipase.

Clin Endosc 2019 Mar 16;52(2):175-181. Epub 2019 Jan 16.

Division of Digestive and Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.

Background/aims: The aim of this study was to describe the diagnostic yield of endoscopic ultrasound (EUS) in patients with isolated elevated levels of amylase and/or lipase.

Methods: A retrospective chart review was conducted at a large academic medical center from 2000 to 2016. Patients were selected based on having elevated amylase, lipase, or both, but without a diagnosis of pancreatitis or known pancreatobiliary disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5946/ce.2018.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453845PMC
March 2019
16 Reads

Pancreas divisum: a reemerging risk factor for pancreatic diseases.

Authors:
Serghei Covantev

Rom J Intern Med 2018 Dec;56(4):233-242

Laboratory of Allergology and Clinical Immunology, "Nicolae Testemitanu" State University of Medicine and Pharmacy, Chisinau, Republic of Moldova.

Pancreas divisum (PD) is the most common developmental anatomic variant of pancreatic duct. The attention towards the PD has grown significantly since there are reports that this condition may cause acute relapsing pancreatitis, chronic pancreatitis and chronic abdominal pain syndrome. Furthermore, over the years, there have been multiple reports of PD associated with different types of tumors. Read More

View Article

Download full-text PDF

Source
https://content.sciendo.com/view/journals/rjim/56/4/article-
Publisher Site
http://dx.doi.org/10.2478/rjim-2018-0022DOI Listing
December 2018
45 Reads

Use of combined methylene blue chromoendoscopy and intravenous secretin for endoscopic therapy in pancreas divisum.

VideoGIE 2018 Dec 2;3(12):397-398. Epub 2018 Oct 2.

Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vgie.2018.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251701PMC
December 2018
13 Reads

Indications and outcomes of duodenum-preserving resection of the pancreatic head in children.

Pediatr Surg Int 2019 Apr 1;35(4):449-455. Epub 2018 Nov 1.

Department of Surgery, University Hospital Kralovske Vinohrady, Prague, Czech Republic.

Aim Of Study: Duodenum-preserving resection of the pancreatic head (DPRPH) with Roux-en-Y pancreatojejunostomy is a procedure used to remove focal pathological lesions of the pancreatic head. Although predominantly used in adult patients, it is both safe and effective in children. The aim of this study was to review our experience with this procedure, with focus on its indications, complications and long-term outcomes. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00383-018-4410-6
Publisher Site
http://dx.doi.org/10.1007/s00383-018-4410-6DOI Listing
April 2019
34 Reads

Gene Therapy for Pancreatic Diseases: Current Status.

Int J Mol Sci 2018 Oct 31;19(11). Epub 2018 Oct 31.

Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757, Aasahimachi-Dori, Chuo-Ku, Niigata 951-8510, Japan.

The pancreas is a key organ involved in digestion and endocrine functions in the body. The major diseases of the pancreas include pancreatitis, pancreatic cancer, cystic diseases, pancreatic divisum, islet cell tumors, endocrine tumors, diabetes mellitus, and pancreatic pain induced by these diseases. While various therapeutic methodologies have been established to date, however, the improvement of conventional treatments and establishment of novel therapies are essential to improve the efficacy. Read More

View Article

Download full-text PDF

Source
http://www.mdpi.com/1422-0067/19/11/3415
Publisher Site
http://dx.doi.org/10.3390/ijms19113415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275054PMC
October 2018
17 Reads

In-hospital and 90-day outcomes after total pancreatectomy with islet autotransplantation for pediatric chronic and acute recurrent pancreatitis.

Am J Transplant 2019 04 6;19(4):1187-1194. Epub 2018 Dec 6.

Division of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Total pancreatectomy with islet autotransplantation (TPIAT) is used to treat debilitating chronic pancreatitis (CP) and acute recurrent pancreatitis (ARP) that has failed medical and endoscopic therapy. We performed a retrospective review of TPIAT patients at a free-standing children's hospital to evaluate perioperative outcomes. Twenty patients (median age 13, 65% female) underwent TPIAT (2015 through 2017). Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajt.15150
Publisher Site
http://dx.doi.org/10.1111/ajt.15150DOI Listing
April 2019
24 Reads

The Role of Endotherapy in Recurrent Acute Pancreatitis.

Gastrointest Endosc Clin N Am 2018 Oct 1;28(4):455-476. Epub 2018 Aug 1.

Columbia University Medical Center, 161 Fort Washington Avenue, Suite 852, New York, NY 10032, USA. Electronic address:

Patients with recurrent acute pancreatitis (RAP) have few treatment options available to them to manage their symptoms or prevent progression to chronic pancreatitis. At present, endotherapy is typically pursued as a means to achieve symptom remission and reduce rates of recurrence, hospitalization, abdominal pain, narcotic use, and surgical intervention. However, evidence that endotherapy effectively alters the natural history of disease remains limited. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.giec.2018.05.001DOI Listing
October 2018
17 Reads

Annular pancreas: endoscopic and pancreatographic findings from a tertiary referral ERCP center.

Gastrointest Endosc 2019 02 18;89(2):322-328. Epub 2018 Sep 18.

Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Background And Aims: Annular pancreas is a congenital anomaly whereby pancreatic tissue encircles the duodenum. Current knowledge of endoscopic findings of annular pancreas is limited to small case series. The aim of this study was to describe the endoscopic and pancreatographic findings of patients with annular pancreas at a large tertiary care ERCP center. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00165107183303
Publisher Site
http://dx.doi.org/10.1016/j.gie.2018.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679934PMC
February 2019
33 Reads