382 results match your criteria Pancreas Divisum Imaging


Complex Pancreaticobiliary Maljunction with Pancreas Divisum and Obstructive Pseudocyst.

J Clin Imaging Sci 2020 25;10:31. Epub 2020 May 25.

Departments of Radiology, Tripler Army Medical Center, 1 Jarrett White Rd., Honolulu, Hawaii, United States.

Pancreaticobiliary maljunction (PBM) is the congenital junction of the bile and pancreatic ducts into a common channel located anatomically outside of the duodenal wall. The complex type (Type D) is the rarest type and occurs in conjunction with other pancreaticobiliary anomalies. We present a case of complex PBM with pancreas divisum presenting as acute pancreatitis and obstructive symptoms secondary to a pancreatic pseudocyst. Read More

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http://dx.doi.org/10.25259/JCIS_17_2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294320PMC

Synchronous Periampullary Tumors in a Patient With Pancreas Divisum and Neurofibromatosis Type 1.

Front Genet 2020 28;11:395. Epub 2020 Apr 28.

Laboratório de Medicina Genômica, Centro de Pesquisa Experimental, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

Introduction: In this study, we describe for the first time a Neurofibromatosis type 1 patient with pancreas divisum, multiple periampullary tumors and germline pathogenic variants in and genes.

Case Report: A 62-year-old female NF1 patient presented with weakness, choluria, nausea, and diffuse abdominal pain to an emergency room service. Magnetic resonance imaging revealed an abdominal mass involving the periampullary region and pancreas divisum. Read More

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http://dx.doi.org/10.3389/fgene.2020.00395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212385PMC

Role of magnetic resonance cholangiopancreatography (MRCP) in learning anatomical variations in pancreatic duct.

J Pak Med Assoc 2020 Mar;70(3):472-476

Department of Anatomy, United Medical & Dental College, affiliated by Jinnah Sindh Medical University, Karachi, Pakistan.

Objective: To assess the frequency of anatomical variations of pancreatic duct through magnetic resonance cholangiography pancreatography. .

Methods: The cross-sectional prospective study was conducted from May 2011 to December 2012 at the Department of Anatomy, Institute of Basic Medical Sciences (IBMS), Dow University of Health Sciences, Karachi, in collaboration with the Department of Radiology, Aga Khan University Hospital, Karachi. Read More

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http://dx.doi.org/10.5455/JPMA.15767DOI Listing

Secretin Improves Visualization of Nondilated Pancreatic Ducts in Children Undergoing MRCP.

AJR Am J Roentgenol 2020 04 5;214(4):917-922. Epub 2020 Feb 5.

Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229.

The objective of our study was to assess whether secretin improves visualization of a nondilated pancreatic duct and whether it increases identification of variant duct anatomy on MRCP in pediatric patients. This study is a delayed retrospective review of MRCP images that were prospectively obtained of 50 volunteers without a history of pancreatic disease who ranged in age from 6 to 15 years old. MRCP images (coronal 3D fast recovery fast spin-echo [FSE] and coronal single-shot FSE fat-saturated sequences) obtained before and after secretin administration were separated for review by three radiologists (reviewers 1-3). Read More

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http://dx.doi.org/10.2214/AJR.19.21798DOI Listing

Cystic fibrosis transmembrane conductance regulator functional evaluations in a G542X+/- IVS8Tn:T7/9 patient with acute recurrent pancreatitis.

World J Clin Cases 2019 Nov;7(22):3757-3764

Cystic Fibrosis Center, Azienda Ospedaliera Universitaria Integrata Verona, Verona 37126, Italy.

Background: Acute recurrent pancreatitis (ARP) is characterized by episodes of acute pancreatitis in an otherwise normal gland. When no cause of ARP is identifiable, the diagnosis of "idiopathic" ARP is given. Mutations in the cystic fibrosis transmembrane conductance regulator () gene increase the risk of ARP by 3- to 4-times compared to the general population, while cystic fibrosis (CF) patients present with a 40- to 80-times higher risk of developing pancreatitis. Read More

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http://dx.doi.org/10.12998/wjcc.v7.i22.3757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887611PMC
November 2019

Case report on Ansa Pancreatica: An Uncommon Cause Accounting for Recurrent Pancreatitis in Children.

J Pak Med Assoc 2019 Nov;69(11):1759-1761

Department of Pediatrics, Shifa College of Medicine, Shifa international Hospital, Islamabad, Pakistan.

Acute recurrent pancreatitis is a rare entity in children. It can be caused by a number of reasons, anatomical variations being one of them. Panctreatica divisum is the most common form of ductal anomaly while ansa pancreatica has been the least studied and explored. Read More

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http://dx.doi.org/10.5455/JPMA.29846.DOI Listing
November 2019

Separate pancreatic ducts draining into a type IV choledochal cyst: simultaneous anatomical variants in a child suffering from cholelithiasis and acute pancreatitis.

Surg Radiol Anat 2020 Apr 9;42(4):449-452. Epub 2019 Nov 9.

Section of Radiological Sciences, Department of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, Policlinico "G. Martino" Via Consolare Valeria 1, 98100, Messina, Italy.

The biliary tree and the pancreatic ducts originate from different buds of the primitive foregut. A plethora of anatomical variants and congenital anomalies have been described for both the biliary and the pancreatic duct systems, although they are usually asymptomatic. However, in some cases, these abnormalities can lead to serious clinical scenarios, especially when involving the biliopancreatic junction, with consequent mixing and reflux of the two different juices. Read More

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http://dx.doi.org/10.1007/s00276-019-02377-7DOI Listing

Performance Characteristics of Magnetic Resonance Imaging in Patients With Pancreas Divisum.

Pancreas 2019 Nov/Dec;48(10):1343-1347

From the Division of Digestive Diseases, Department of Medicine, Emory University school of Medicine, Atlanta, GA.

Objective: This study was designed to assess the diagnostic accuracy of standard nonsecretin-enhanced preprocedural magnetic resonance imaging/cholangiopancreatography (MRI/MRCP) in patients with and without pancreas divisum.

Methods: Patients undergoing MRI/MRCP followed by endoscopic retrograde cholangiopancreatography with between 2009 and 2016 were reviewed. The diagnostic accuracy of the MRI/MRCP was evaluated against the pancreatography. Read More

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http://dx.doi.org/10.1097/MPA.0000000000001437DOI Listing
November 2019

Identification and management of pancreas divisum.

Expert Rev Gastroenterol Hepatol 2019 Nov 8;13(11):1089-1105. Epub 2019 Nov 8.

Indiana University School of Medicine, Division of Gastroenterology, Indianapolis, IN, USA.

: Pancreas divisum is the most common congenital malformation of the pancreas with the majority asymptomatic. The etiological role, pathogenesis, clinical significance and management of pancreas divisum in pancreatic disease has not been clearly defined and our understanding is yet to be fully elucidated.: This review describes the role of pancreas divisum in the development of pancreatic disease and the ambiguity related to it. Read More

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http://dx.doi.org/10.1080/17474124.2019.1685871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872911PMC
November 2019
1 Read

Pancreas divisum inversus.

Clin Anat 2020 Jul 12;33(5):646-652. Epub 2019 Oct 12.

Radiology Unit, Department of Experimental, Diagnostic and Speciality Medicine, Sant'Orsola Hospital, University of Bologna, Bologna, Italy.

Pancreatic duct variations are usually diagnosed incidentally, in particular when using magnetic resonance cholangiopancreatography (MRCP), the most accurate imaging modality for depicting the pancreatic ductal system. However, the frequency and the embryologic development of pancreatic variants have not been well investigated. The purpose of this prospective study was to investigate the frequency of pancreatic ductal variants, providing potential explanations of their embryologic basis. Read More

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http://dx.doi.org/10.1002/ca.23475DOI Listing
July 2020
2 Reads

Pancreatitis in the developmentally anomalous pancreas.

Abdom Radiol (NY) 2020 05;45(5):1316-1323

Department of Radiology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.

Developmental anomalies of the pancreas include more common entities such as pancreas divisum and annular pancreas, and unusual entities such as heterotopic pancreas. While these anomalies can present a diagnostic challenge to the radiologist, when the pancreatic tissue involved in these processes develops pancreatitis, the radiographic appearance can present a diagnostic dilemma. Awareness of these pancreatic anomalies and familiarity with their appearance when inflamed is necessary to distinguish pancreatitis in the developmentally anomalous pancreas from other inflammatory or neoplastic processes. Read More

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http://dx.doi.org/10.1007/s00261-019-02197-8DOI Listing
May 2020
1 Read

Treatment of Difficult Minor Papilla Cannulation in Patients of Pancreatic Divisum: Using Endoscopic Ultrasonography-guided Puncture Combined With Endoscopic Retrograde Cholangiopancreatography: 2 Cases and Literature Review.

Surg Laparosc Endosc Percutan Tech 2019 Aug;29(4):e60-e64

Department of Gastroenterology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.

Context: Pancreas divisum (PD), the most common congenital anatomic variation of the pancreatic ductal system, is still rare in clinical practice. Endoscopic retrograde cholangiopancreatography (ERCP) is the first-line treatment for patients with symptomatic PD. However, even by experienced endoscopists, the procedure of ERCP can fail in 3% to 10% of cases. Read More

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http://Insights.ovid.com/crossref?an=00129689-201908000-0002
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http://dx.doi.org/10.1097/SLE.0000000000000686DOI Listing
August 2019
5 Reads

Diagnosis and treatment of pancreas divisum: A literature review.

Hepatobiliary Pancreat Dis Int 2019 Aug 20;18(4):332-336. Epub 2019 May 20.

Division of General Surgery, Sanchinarro Hospital, San Pablo University, calle oña 10, 28050 Madrid, Spain.

Background: Pancreas divisum is a congenital embryological disease caused by a lack of fusion between the ventral and dorsal pancreatic ducts in the early stages of embryogenesis. Recurrent acute pancreatitis, chronic pancreatitis or chronic abdominal pain are the main clinical syndromes at presentation and occur in only 5% of the patients with pancreas divisum. This review aimed to discuss diagnosis and treatment strategies in patients with symptomatic pancreas divisum. Read More

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http://dx.doi.org/10.1016/j.hbpd.2019.05.004DOI Listing
August 2019
17 Reads

Is MRCP necessary to diagnose pancreas divisum?

BMC Med Imaging 2019 04 29;19(1):33. Epub 2019 Apr 29.

Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, INF 110, 69120, Heidelberg, Germany.

Background: The purpose of this study is to compare the performance of three-dimensional magnetic resonance cholangiopancreatography (3D-MRCP) with non-MRCP T2-weighted magnetic resonance imaging (MRI) sequences for diagnosis of pancreas divisum (PD).

Methods: This is a retrospective study of 342 consecutive patients with abdominal MRI including 3D-MRCP. 3D-MRCP was a coronal respiration-navigated T2-weighted sequence with 1. Read More

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http://dx.doi.org/10.1186/s12880-019-0329-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489286PMC
April 2019
11 Reads

[Pancreatic Mass or Cyst? Diagnostic Dilemma].

Dig Dis 2019 8;37(6):521-524. Epub 2019 Apr 8.

Division of Gastroenterology and Hepatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

A santorinicele is a rare anomaly defined as focal cystic dilation of the terminal portion of the dorsal pancreatic duct at the minor papilla. Importantly this anomaly has been suggested as a possible cause of relative stenosis of the minor papilla. This anomaly has been associated with pancreatic divisum and recurrent acute pancreatitis. Read More

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http://dx.doi.org/10.1159/000497448DOI Listing
December 2019
19 Reads

Association between chronic asymptomatic pancreatic hyperenzymemia and pancreatic ductal anomalies: a magnetic resonance cholangiopancreatography study.

Abdom Radiol (NY) 2019 07;44(7):2494-2500

Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Purpose: Elucidating the association between pancreatic ductal anomalies and chronic asymptomatic pancreatic hyperenzymemia using magnetic resonance cholangiopancreatography.

Methods: We conducted a single-center, retrospective, case-control study. The healthy community group comprised 554 subjects who participated in a paid, whole-body health checkup program. Read More

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http://dx.doi.org/10.1007/s00261-019-02004-4DOI Listing
July 2019
13 Reads

Identifying Factors Predicting Response to Endoscopic Management of Chronic Pancreatitis Secondary to Pancreas Divisum.

J Gastrointest Surg 2020 Mar 18;24(3):585-589. Epub 2019 Mar 18.

Department of Surgery, University of Louisville, Louisville, KY, USA.

Introduction: Appropriately selecting patients with chronic pancreatitis associated with pancreas divisum (PD) for endoscopic retrograde cholangiopancreatography (ERCP)-based therapy versus surgery remains difficult. The objective of this study was to identify factors that predict success or failure of ERCP for treatment of chronic pancreatitis in PD.

Methods: Patients undergoing ERCP for a diagnosis of PD and pancreatitis between 2008 and 2016 were identified and grouped according to whether they required one or two ERCPs or three or more ERCPs. Read More

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http://dx.doi.org/10.1007/s11605-019-04122-2DOI Listing
March 2020
8 Reads

Intraductal papillary mucinous neoplasm of the main duct in a patient with pancreas divisum.

Rev Esp Enferm Dig 2019 Apr;111(4):322

Cirugía General, Complejo Hospitalario de Navarra.

Pancreas divisum is a congenital anomaly present in 5-10% of the population and is usually asymptomatic. Pancreatic intraductal papillary mucinous neoplasms (IPMN) are mucinous cystic tumors that have malignant potential and are classified according to their location as IPMN of the main duct, branch duct or mixed type. Larger lesions and those originating in the main duct have an increased risk of malignancy. Read More

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http://dx.doi.org/10.17235/reed.2019.5959/2018DOI Listing
April 2019
9 Reads

Anterograde Endoscopic Ultrasound-Guided Pancreatic Duct Drainage: A Technical Review.

Dig Dis Sci 2019 07 7;64(7):1770-1781. Epub 2019 Feb 7.

Section of Digestive Diseases, West Virginia University Medicine, PO Box 9161, One Medical Center Drive, Morgantown, WV, 26506-9161, USA.

The advancement of pancreatic endotherapy has increased the availability of minimally invasive endoscopic pancreatic ductal drainage techniques. In this regard, familiarity with endoscopic ultrasound-guided pancreatic duct drainage (EUS-PDD) is critical for treatment of obstructed pancreatic ductal systems, especially in nonsurgical candidates and in patients desiring a minimally invasive approach. Two distinct forms of EUS-PDD exist, viz. Read More

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http://dx.doi.org/10.1007/s10620-019-05495-9DOI Listing
July 2019
10 Reads

The Utility of Endoscopic Ultrasound in Patients with Isolated Elevations in Serum Amylase and/or Lipase.

Clin Endosc 2019 Mar 16;52(2):175-181. Epub 2019 Jan 16.

Division of Digestive and Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.

Background/aims: The aim of this study was to describe the diagnostic yield of endoscopic ultrasound (EUS) in patients with isolated elevated levels of amylase and/or lipase.

Methods: A retrospective chart review was conducted at a large academic medical center from 2000 to 2016. Patients were selected based on having elevated amylase, lipase, or both, but without a diagnosis of pancreatitis or known pancreatobiliary disease. Read More

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http://dx.doi.org/10.5946/ce.2018.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453845PMC
March 2019
16 Reads

Pancreas divisum: a reemerging risk factor for pancreatic diseases.

Authors:
Serghei Covantev

Rom J Intern Med 2018 Dec;56(4):233-242

Laboratory of Allergology and Clinical Immunology, "Nicolae Testemitanu" State University of Medicine and Pharmacy, Chisinau, Republic of Moldova.

Pancreas divisum (PD) is the most common developmental anatomic variant of pancreatic duct. The attention towards the PD has grown significantly since there are reports that this condition may cause acute relapsing pancreatitis, chronic pancreatitis and chronic abdominal pain syndrome. Furthermore, over the years, there have been multiple reports of PD associated with different types of tumors. Read More

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https://content.sciendo.com/view/journals/rjim/56/4/article-
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http://dx.doi.org/10.2478/rjim-2018-0022DOI Listing
December 2018
45 Reads

Annular pancreas: endoscopic and pancreatographic findings from a tertiary referral ERCP center.

Gastrointest Endosc 2019 02 18;89(2):322-328. Epub 2018 Sep 18.

Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Background And Aims: Annular pancreas is a congenital anomaly whereby pancreatic tissue encircles the duodenum. Current knowledge of endoscopic findings of annular pancreas is limited to small case series. The aim of this study was to describe the endoscopic and pancreatographic findings of patients with annular pancreas at a large tertiary care ERCP center. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165107183303
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http://dx.doi.org/10.1016/j.gie.2018.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679934PMC
February 2019
33 Reads

Dilation of the dorsal pancreatic duct in an asymptomatic patient with pancreas divisum.

Dig Liver Dis 2019 01 8;51(1):169. Epub 2018 Aug 8.

Gastroenterology Department, Hospital de Braga, Braga, Portugal. Electronic address:

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http://www.dldjournalonline.com/article/S1590865818308740/pd
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https://linkinghub.elsevier.com/retrieve/pii/S15908658183087
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http://dx.doi.org/10.1016/j.dld.2018.07.037DOI Listing
January 2019
24 Reads

The Role of Endoscopic Ultrasonography and Magnetic Resonance Cholangiopancreatography in Patients With Acute Pancreatitis After Negative Computed Tomography Findings of the Etiology.

Pancreas 2018 10;47(9):1165-1171

Radiology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

Objectives: We aimed to investigate the roles of endoscopic ultrasonography (EUS) and magnetic resonance cholangiopancreatography (MRCP) in detecting the causes of acute pancreatitis after negative computed tomography (CT) findings.

Methods: Demographic characteristics, blood test results, the severity of pancreatitis, and definite or possible etiology of pancreatitis by EUS and MRCP were evaluated prospectively in 65 consecutively admitted patients after negative CT findings.

Results: Endoscopic ultrasonography and/or MRCP confirmed the definite causes of pancreatitis in 47. Read More

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http://Insights.ovid.com/crossref?an=00006676-201810000-0001
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http://dx.doi.org/10.1097/MPA.0000000000001149DOI Listing
October 2018
15 Reads

Rare case of severe acute pancreatitis following over-the-scope clip-assisted duodenal endoscopic mucosal resection using a cap-fitted endoscope in a patient with pancreas divisum.

Dig Endosc 2018 09 21;30(5):679. Epub 2018 Jun 21.

Department of Gastroenterology, NTT Medical Center Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/den.13200DOI Listing
September 2018
10 Reads

Frequency of bile duct confluence variations in subjects with pancreas divisum: an analysis of MRCP findings.

Diagn Interv Radiol 2018 Mar-Apr;24(2):72-76

Department of Radiology, Ankara University School of Medicine, Ankara, Turkey.

Purpose: We aimed to evaluate the frequency of bile duct branching pattern variations at the hepatic confluence in patients with pancreas divisum (PD).

Methods: A search was performed through the hospital database using the keyword "pancreas divisum" to identify patients. The magnetic resonance cholangiopancreatography (MRCP) images of 137 patients who were diagnosed with PD between August 2011 and November 2016 were retrospectively analyzed for the presence of bile duct variations. Read More

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http://dx.doi.org/10.5152/dir.2018.17200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873505PMC
October 2018
13 Reads

Pancreaticopleural fistula: a rare cause of pleural empyema.

Acta Chir Belg 2019 Dec 2;119(6):396-399. Epub 2018 May 2.

Department of Hepatobiliary, Transplantation and Endocrine Surgery, University Hospital Antwerp , Antwerp , Belgium.

Pancreaticopleural fistula (PPF) is a rare complication of acute or chronic pancreatitis. When the pancreatic duct disrupts, pancreatic fluid may leak into the retroperitoneum and fistulate into the pleural cavity. Patients usually present with thoracic complaints, making it hard to suspect an abdominal etiology. Read More

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http://dx.doi.org/10.1080/00015458.2018.1470293DOI Listing
December 2019
24 Reads

Interpreting body MRI cases: classic findings in abdominal MRI.

Abdom Radiol (NY) 2018 10;43(10):2790-2808

Radiology, Thomas Jefferson University Hospital, 132 South 10th Street, Suite 1087, Main Building, Philadelphia, PA, 19107, USA.

Few things in radiology are "pathognomonic" in their appearance or presentation. However, having an awareness of those findings which are specific to a certain entity is important when interpreting imaging studies. These classic findings can be identified with many imaging modalities, but no modality provides as many recognizable observations as an MRI. Read More

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http://dx.doi.org/10.1007/s00261-018-1551-yDOI Listing
October 2018
18 Reads

Comparison of EUS with MRCP in idiopathic acute pancreatitis: a systematic review and meta-analysis.

Gastrointest Endosc 2018 May 7;87(5):1180-1188.e9. Epub 2017 Dec 7.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, People's Republic of China.

Background And Aims: Idiopathic acute pancreatitis (IAP) poses a diagnostic challenge for gastroenterologists, because confirmation of the disease etiology has important implications for the selection of the best possible treatment and the prevention of possible recurrence or the development of chronic pancreatitis (CP). ERCP, EUS, and MRCP typically are used to diagnose IAP when conventional radiologic methods fail. However, their exact role in the diagnosis of IAP has not yet been determined. Read More

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http://dx.doi.org/10.1016/j.gie.2017.11.028DOI Listing
May 2018
43 Reads

Yield of Endoscopic Ultrasound in Children and Adolescent With Acute Recurrent Pancreatitis.

J Pediatr Gastroenterol Nutr 2018 03;66(3):461-465

Department of Pediatric Gastroenterology.

Objectives: Endoscopic ultrasound (EUS) is an established tool for evaluation of adults with acute recurrent pancreatitis (ARP) whereas data in pediatrics is limited. Our study assessed the role of EUS in identifying etiology including changes of chronic pancreatitis (CP) in children and adolescents with ARP.

Methods: Children with ARP (≥2 episodes of acute pancreatitis [AP]) were prospectively evaluated with a detailed clinical proforma and EUS. Read More

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http://dx.doi.org/10.1097/MPG.0000000000001855DOI Listing
March 2018
24 Reads

Groove Pancreatitis: Endoscopic Treatment via the Minor Papilla and Duct of Santorini Morphology.

Gut Liver 2018 Mar;12(2):208-213

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Background/aims: Groove pancreatitis (GP) is an uncommon disease involving the pancreaticoduodenal area. Possible pathogenesis includes obstructive pancreatitis in the duct of Santorini and impaired communication with the duct of Wirsung, minor papilla stenosis, and leakage causing inflammation. Limited data regarding endoscopic treatment have been published. Read More

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http://dx.doi.org/10.5009/gnl17170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832346PMC
March 2018
19 Reads

Pancreatic hemi-agenesis in MEN1: A clinical report.

Eur J Med Genet 2018 Apr 23;61(4):181-184. Epub 2017 Nov 23.

Centre for Human Genetics, KU Leuven, Leuven, Belgium.

We first describe a patient with multiple endocrine neoplasia type 1 (MEN1) and dorsal pancreatic hemi-agenesis. Previously, pancreas divisum has been reported in MEN1. Recent data in mice have elucidated the molecular mechanisms of pancreatic endoderm specification. Read More

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http://dx.doi.org/10.1016/j.ejmg.2017.11.013DOI Listing
April 2018
41 Reads

The endoscopic ultrasound-assisted Rendez-Vous technique for treatment of recurrent pancreatitis due to pancreas divisum and ansa pancreatica.

Rev Esp Enferm Dig 2017 Nov;109(11):798-800

Gastroenterología y Hepatología, Hospital Universitario Ramón y Cajal. Universidad de Alcalá. IRICYS.

Endoscopic treatment of pancreatic ductal malformations causing recurrent acute pancreatitis, such as pancreas divisum or ansa pancreatica, is mainly based on the sphincterotomy of the minor papilla. However, the technical complexity of conventional endoscopic retrograde cholangiopancreatography (ERCP) is increased in patients presenting anatomical variants like these and it may be unsuccessful. We report the case of a pancreas divisum combined with ansa pancreatica and describe the cannulation and sphincterotomy of the minor papilla using an ultrasound-assisted Rendez-Vous technique. Read More

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http://dx.doi.org/10.17235/reed.2017.4949/2017DOI Listing
November 2017
39 Reads

Pancreatitis in Patients With Pancreas Divisum.

Pancreas 2017 Nov/Dec;46(10):e80-e81

Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ Division of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, AZ; Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ; Department of Radiology, Mayo Clinic, Scottsdale, AZ; Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ

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http://Insights.ovid.com/crossref?an=00006676-201711000-0002
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http://dx.doi.org/10.1097/MPA.0000000000000938DOI Listing
June 2018
34 Reads

The crossing duct sign.

Abdom Radiol (NY) 2018 06;43(6):1506-1507

Department of Radiology, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, Hong Kong SAR.

Pancreas divisum is a common variation in pancreatic ductal anatomy present in up to 10% of the population with variable clinical importance. The crossing duct sign refers to the appearance of dominant dorsal duct crossing the intrapancreatic common bile duct to empty into the minor papilla, best illustrated on maximum intensity projection images from MRCP. Read More

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http://dx.doi.org/10.1007/s00261-017-1312-3DOI Listing
June 2018
14 Reads

Endoscopic therapy for patients with pancreaticobiliary maljunction: a follow-up study.

Oncotarget 2017 Jul;8(27):44860-44869

Department of Gastroenterology, Digestive Endoscopy Center, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Background: Data on the experience of endoscopic retrograde cholangiopancreatography (ERCP) in the management of pancreaticobiliary maljunction (PBM) is limited.

Methods: A retrospective review of patients with PBM who underwent therapeutic ERCP at our endoscopy center between January 2008 and January 2016 was performed. Demographic, clinical, radiological and endoscopic data was documented. Read More

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http://dx.doi.org/10.18632/oncotarget.16228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546526PMC
July 2017
19 Reads

Pancreas Divisum in Children and Duodenum-Preserving Resection of the Pancreatic Head.

Eur J Pediatr Surg 2018 Jun 29;28(3):250-254. Epub 2017 Mar 29.

Department of Internal Medicine, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Czech Republic.

Introduction:  A retrospective study was performed to evaluate the clinical features, diagnostic methods, and treatment alternatives in children with pancreas divisum (PD).

Materials And Methods:  Patients who underwent treatment for PD between 1999 and 2014 at our department were evaluated for sex, age, presenting symptoms, physical examination findings, biochemical markers, diagnostic methods, treatment modalities, and results of treatment during follow-up.

Results:  Seven patients who underwent treatment of symptomatic PD were included in the study. Read More

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http://dx.doi.org/10.1055/s-0037-1599838DOI Listing
June 2018
21 Reads

Patients with pancreas divisum have an increased risk of developing pancreatico-biliary neoplasms.

Authors:
R Manfredi

Diagn Interv Imaging 2017 02;98(2):99-100

University of Rome "A. Gemelli", Largo A. Gemelli 8, 00168 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.diii.2017.01.007DOI Listing
February 2017
9 Reads

Anatomic variations of the pancreatic duct and their relevance with the Cambridge classification system: MRCP findings of 1158 consecutive patients.

Radiol Oncol 2016 Dec 8;50(4):370-377. Epub 2016 Sep 8.

Department of Surgery, Bozyaka Training and Research Hospital, Izmir, Turkey.

Background: The study was conducted to evaluate the frequencies of the anatomic variations and the gender distributions of these variations of the pancreatic duct and their relevance with the Cambridge classification system as morphological sign of chronic pancreatitis using magnetic resonance cholangiopancreatography (MRCP).

Patients And Methods: We retrospectively reviewed 1312 consecutive patients who referred to our department for MRCP between January 2013 and August 2015. We excluded 154 patients from the study because of less than optimal results due to imaging limitations or a history of surgery on pancreas. Read More

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http://dx.doi.org/10.1515/raon-2016-0041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120578PMC
December 2016
33 Reads

Low Alcohol and Cigarette Use Is Associated to the Risk of Developing Chronic Pancreatitis.

Pancreas 2017 02;46(2):225-229

From the *Gastrointestinal Endoscopy Unit, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan; and †Gastroenterology Unit 1, Scientific Institute for Digestive Disease 'S. de Bellis' Hospital, Castellana Grotte, Italy ‡Institute for Digestive Liver Health, University College, London, United Kingdom; §Section of Gastroenterology Boston University School of Medicine Boston Medical Center, Boston, MA; ∥Department of Gastroenterology, Hepatology Infectious Diseases, Otto-von-Guericke University, Magdeburg, Germany; and ¶Department of Clinical Experimental Medicine, School of Medicine, University of Parma, Parma; and #Department of Radiology Center for Experimental Imaging, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

Objectives: The aim of this study was to investigate the contribution of smoking and alcohol intake and pancreas divisum on the risk of developing chronic pancreatitis (CP).

Methods: Consecutive patients with CP who underwent secretin-enhanced magnetic resonance cholangiopancreatography were compared with consecutive patients without pancreatic disease who underwent secretin-enhanced magnetic resonance cholangiopancreatography for irritable bowel syndrome.

Results: We enrolled 145 consecutive CP patients and 103 irritable bowel syndrome patients from 2010 to 2014. Read More

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http://dx.doi.org/10.1097/MPA.0000000000000737DOI Listing
February 2017
49 Reads

An impacted minor papilla stone in a patient with pancreas divisum that caused acute exacerbation of chronic pancreatitis: a case report.

Nihon Shokakibyo Gakkai Zasshi 2016 ;113(11):1916-1922

Department of Gastroenterology, Suzuka General Hospital.

A 75-year-old woman with epigastric pain was admitted to our emergency department. She was diagnosed with an acute exacerbation of chronic pancreatitis based on the results of blood tests and abdominal computed tomography (CT). The abdominal CT and magnetic resonance cholangiopancreatography revealed pancreas divisum. Read More

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http://dx.doi.org/10.11405/nisshoshi.113.1916DOI Listing
March 2017
39 Reads

Chorioretinal coloboma in a patient with pancreas divisum: clinical and imaging features.

Eur J Ophthalmol 2016 Nov 4;26(6):e158-e160. Epub 2016 Nov 4.

Department of Ophthalmology, Vita-Salute University, San Raffaele Scientific Institute, Milan - Italy.

Purpose: To report the case of a 61-year-old woman with pancreas divisum and an asymptomatic chorioretinal coloboma in its 2 forms: complete and partial.

Methods: Case report.

Results: Dilated fundus examination and photograph revealed a complete and partial coloboma in the right eye. Read More

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http://dx.doi.org/10.5301/ejo.5000837DOI Listing
November 2016
10 Reads

[Distal pancreatectomy as surgical option in Pancreas divisum associated with Rubinstein-Taybi syndrome].

Cir Pediatr 2015 Apr 15;28(2):84-87. Epub 2015 Apr 15.

Universidad Peruana de Ciencias Aplicadas. Lima, Perú.

Introduction: The Rubinstein-Taybi syndrome and pancreas divisum are uncommon diseases in children. The Rubinstein-Taybi syndrome diagnosis is only clinical, and mental retardation and dysmorphic features mainly characterize it. The PD relates to idiopathic pancreatitis in 7. Read More

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April 2015
20 Reads

Intrahepatic biliary duct branching patterns, cystic duct anomalies, and pancreas divisum in a tertiary referral center: A magnetic resonance cholangiopancreaticographic study.

Indian J Gastroenterol 2016 Sep 23;35(5):379-384. Epub 2016 Sep 23.

Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, 226 014, India.

Background: Knowledge about anatomic variations in intrahepatic biliary ducts (IHBD) is relevant for performing biliary drainage and for avoiding bile duct injury during cholecystectomy and liver resections. Low insertion of cystic duct (LICD) is a common anatomic variant. Pancreas divisum is the commonest congenital anomaly of pancreas; it has been causally linked with recurrent acute pancreatitis (RAP). Read More

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http://dx.doi.org/10.1007/s12664-016-0693-5DOI Listing
September 2016
54 Reads

The Accuracies of Diagnosing Pancreas Divisum by Magnetic Resonance Cholangiopancreatography and Endoscopic Ultrasound: A Systematic Review and Meta-analysis.

Sci Rep 2016 10 13;6:35389. Epub 2016 Oct 13.

Department of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, China.

Magnetic resonance cholangiopancreatography (MRCP), MRCP after secretin stimulation (S-MRCP) and endoscopic ultrasonography (EUS) are all selected to diagnose pancreas divisum. However, the accuracies of three diagnosis remain unclear. The aim is to address the diagnostic accuracies of MRCP, S-MRCP and EUS on pancreas divisum. Read More

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http://dx.doi.org/10.1038/srep35389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062127PMC
October 2016
38 Reads

Pancreas divisum: A risk factor for pancreaticobiliary tumors - an analysis of 1628 MR cholangiography examinations.

Diagn Interv Imaging 2017 Feb 5;98(2):141-147. Epub 2016 Sep 5.

Department of Surgery, Bozyaka Training and Research Hospital, Izmir, Turkey.

Purpose: This retrospective study was conducted to evaluate the relationships between pancreas divisum, biliary duct anatomical variations and pancreaticobiliary tumors using magnetic resonance cholangiopancreatography (MRCP).

Materials And Method: The MRCP examinations of 1628 patients were retrospectively reviewed for the presence of pancreas divisum, biliary duct anatomical variations and pancreaticobiliary tumors. Of these, 90 patients (31 men, 59 women) with a mean age of 62. Read More

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http://dx.doi.org/10.1016/j.diii.2016.08.004DOI Listing
February 2017
7 Reads

Prospective Endoscopic Ultrasound-Based Approach to the Evaluation of Idiopathic Pancreatitis: Causes, Response to Therapy, and Long-term Outcome.

Am J Gastroenterol 2016 09 21;111(9):1339-48. Epub 2016 Jun 21.

Division of Gastroenterology and Hepatology, Basil I. Hirschowitz Endoscopic Center of Excellence, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Objectives: Although idiopathic pancreatitis is common, the natural history is not well studied, and the best diagnostic approach to both single and multiple attacks remains undefined.

Methods: We prospectively evaluated patients with idiopathic pancreatitis over a 10-year period, and clinical information for each episode was reviewed. Endoscopic ultrasound (EUS) was performed in all patients. Read More

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http://dx.doi.org/10.1038/ajg.2016.240DOI Listing
September 2016
37 Reads

Ectopic Opening of the Common Bile Duct Accompanied by Choledochocele and Pancreas Divisum.

Intern Med 2016 1;55(9):1097-102. Epub 2016 May 1.

Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.

A 32-year-old woman was referred due to abdominal pain and elevated liver enzymes. Computed tomography and magnetic resonance imaging showed ectopic opening of the common bile duct (CBD) into the duodenal bulb. Esophagogastroduodenoscopy showed a hemispheric bulge in the duodenal bulb. Read More

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https://www.jstage.jst.go.jp/article/internalmedicine/55/9/5
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http://dx.doi.org/10.2169/internalmedicine.55.6240DOI Listing
June 2017
37 Reads

Somatostatinoma of the minor duodenal papilla associated with pancreas divisum treated by endoscopic papillectomy.

Endoscopy 2016 14;48 Suppl 1:E135-7. Epub 2016 Apr 14.

Departments of Surgery and Anatomy, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Ribeirão Preto, São Paulo, Brazil.

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http://dx.doi.org/10.1055/s-0042-104928DOI Listing
January 2017
27 Reads

Chronic Pancreatitis: Landmark Papers, Management Decisions, and Future.

Pancreas 2016 May-Jun;45(5):641-50

From the *Department of Internal Medicine, Division of Gastroenterology and Hepatology, Mayo Medical School, Mayo Clinic, Rochester, MN; and †Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan School of Medicine, Ann Arbor, MI.

On May 16, 2015 at the invitation of the American Gastroenterological Association Institute Council E.P.D. Read More

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http://dx.doi.org/10.1097/MPA.0000000000000599DOI Listing
January 2017
14 Reads