413 results match your criteria Pancreas Divisum Imaging

Long-Term Outcomes of Endoscopic Intervention in the Treatment of Symptomatic Pancreas Divisum.

J Healthc Eng 2022 16;2022:8508943. Epub 2022 Apr 16.

Department of Gastroenterology and Hepatology, The First Medical Center of PLA General Hospital, Beijing 100853, China.

To evaluate the efficacy and safety of endoscopic retrograde cholangiopancreatography (ERCP) in the treatment of patients with symptomatic pancreas divisum (PD) and to discuss the possible risk factors of endoscopic reintervention for symptomatic PD. A total of 50 patients with symptomatic PD who underwent ERCP from January 2010 to December 2019 were finally brought into study. All patients were divided into the nonage and the adult group according to their ages. Read More

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Imaging of the Pancreas in New-Onset Diabetes: A Prospective Pilot Study.

Clin Transl Gastroenterol 2022 Jun 1;13(6):e00478. Epub 2022 Jun 1.

Department of Radiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, USA.

Introduction: The aim of this study was to assess the feasibility of cross-sectional imaging for detection of pancreatic cancer (PDAC) in patients with new-onset hyperglycemia and diabetes (NOD).

Methods: We conducted a prospective pilot study from November 2018 to March 2020 within an integrated health system. Patients aged 50-85 years with newly elevated glycemic parameters without a history of diabetes were invited to complete a 3-phase contrast-enhanced computed tomography pancreas protocol scan while participating in the Prospective Study to Establish a NOD Cohort. Read More

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Pancreaticobiliary maljunction and pancreas divisum accompanied with intestinal malrotation: a case report.

BMC Pediatr 2022 02 28;22(1):110. Epub 2022 Feb 28.

Department of General Surgery, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, No. 56 Nalishi Road, Xicheng District, CN, 100045, Beijing, China.

Background: Pancreaticobiliary maljunction is a congenital anatomical abnorma l junction of the pancreatic duct and bile duct into a common channel outside the duodenal wall. Pancreas divisum is also a congenital anatomical abnormality characterized by unfused pancreatic ducts. Intestinal malrotation is caused by the failure of bowel rotation and fixation. Read More

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February 2022

Endoscopic diagnosis of santoriniceles with reverse pancreas divisum.

Gastrointest Endosc 2022 05 31;95(5):1015-1016. Epub 2022 Jan 31.

Department of Gastroenterology, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

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Magnetic Resonance Cholangiopancreatography vs Endoscopy Retrograde Cholangiopancreatography for Detection of Anatomic Variants of the Pancreatic Duct in Children.

J Pediatr 2022 05 19;244:120-124. Epub 2022 Jan 19.

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH; Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH.

Objective: To compare the efficacy of magnetic resonance cholangiopancreatography (MRCP) with endoscopy retrograde cholangiopancreatography (ERCP) in children for the identification of pancreatic duct variants.

Study Design: We identified children with a pancreatic duct variant by ERCP and separately queried our MRCP database for similar variants. Patients with a paired ERCP-MRCP were reviewed. Read More

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Pancreas Divisum as a Rare Etiology of Recurrent Pancreatitis: A Rare Case Ever Documented and Reported In Indonesia.

Acta Med Indones 2021 Oct;53(4):465-468

Division of Gastroenterohepatology Department of Internal Medicine Faculty of Medicine - University of Padjadjaran Hasan Sadikin General Hospital Bandung - Indonesia.

Pancreas divisum is an abnormal condition of pancreas duct that occurs from organogenesis. This abnormal condition defined as a failure in fusion between dorsal and ventral part of the pancreas. The incidence reported 4%-14% in general population. Read More

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October 2021

Double plastic stent implantation for recurrent acute pancreatitis with incomplete pancreas divisum: a case report and literature review.

J Int Med Res 2021 Nov;49(11):3000605211060142

Department of Gastroenterology, Hebei Key Laboratory of Gastroenterology, Hebei Institute of Gastroenterology, 71213Second Hospital of Hebei Medical University, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.

Pancreas divisum (PD) is a common pancreatic malformation caused by the failure of fusion between ventral and dorsal pancreatic ducts. There is a small branch of communication between the two systems in incomplete PD, and this variation has an incidence of 15%. A 43-year-old female patient presented to our department with recurrent abdominal pain. Read More

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November 2021

Fully laparoscopic pancreaticojejunostomy, Puestow procedure (with video).

J Surg Case Rep 2021 Sep 22;2021(9):rjab397. Epub 2021 Sep 22.

Department of Hepatobiliary Surgery, Clínica Las Condes, Estoril 450, Las Condes, Santiago, Chile.

Chronic pancreatitis usually requires medical treatment and, in rare cases, surgical intervention. The most frequent cause of consultation is chronic pain that is difficult to manage, and therapeutic options such as endoscopy can resolve most problems without surgery. However, when these options fail, surgical management is necessary. Read More

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September 2021

Impact of genetic testing and smoking on the distribution of risk factors in patients with recurrent acute and chronic pancreatitis.

Scand J Gastroenterol 2022 Jan 18;57(1):91-98. Epub 2021 Oct 18.

Pancreatitis Center, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

Objective: The aim of the present study is to assess the impact of smoking dose and duration on the distribution of risk factor(s) in patients with RAP and CP, and the impact of genetic testing on the distribution of risk factor(s) in patients with idiopathic RAP and CP.

Methods: All adult patients with RAP and CP referred to a multidisciplinary pancreatitis clinic between 2010 and 2017 were evaluated. Risk factors included alcohol and smoking, hypertriglyceridemia, biliary, and other etiologies. Read More

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January 2022

Value of Magnetic Resonance Cholangiopancreatography in Santorinicele and Wirsungocele.

Curr Med Imaging 2021 ;17(12):1451-1459

Medical Imaging Center, Shenzhen Hospital of Southern Medical University, Shenzhen, 518100, China.

Background: Former studies showed that magnetic resonance cholangiopancreatography (MRCP) is useful in diagnosing the presence of santorinicele; however, few studies have evaluated MRCP in diagnosing wirsungocele and the association between pancreatitis and santorinicele or wirsungocele. The purpose of the study was to explore the performance of MRCP in diagnosing santorinicele and wirsungocele and investigate the potential association among pancreatitis, pancreas divisum, and santorinicele or wirsungocele.

Methods: Sixty-five patients (mean age, 55. Read More

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January 2022

Current advances in the management of chronic pancreatitis.

Dis Mon 2021 Dec 24;67(12):101225. Epub 2021 Jun 24.

Department of Gastroenterology and Advanced endoscopy, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA. Electronic address:

Chronic pancreatitis is characterized by irreversible destruction of pancreatic parenchyma and its ductal system resulting from longstanding inflammation, leading to fibrosis and scarring due to genetic, environmental, and other risk factors. The diagnosis of chronic pancreatitis is made based on a combination of clinical features and characteristic findings on computed tomography or magnetic resonance imaging. Abdominal pain is the most common symptom of chronic pancreatitis. Read More

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December 2021

Pancreatic pseudocyst, pancreatitis, and incomplete pancreas divisum in a child treated with endotherapy: a case report.

J Int Med Res 2021 May;49(5):3000605211014395

Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Qinghai University, Xining, China.

Pancreatic divisum (PD) is caused by the lack of fusion of the pancreatic duct during the embryonic period. Considering the incidence rate of PD, clinicians lack an understanding of the disease, which is usually asymptomatic. Some patients with PD may experience recurrent pancreatitis and progress to chronic pancreatitis. Read More

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[Pancreas divisum and pancreatitis].

Radiologe 2021 Jun 3;61(6):541-547. Epub 2021 May 3.

Klinik für Diagnostische & Interventionelle Radiologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 420, 69120, Heidelberg, Deutschland.

Clinical/methodological Issue: Diagnostic and clinical relevance of pancreas divisum.

Standard Radiological Methods: Ultrasonography (US), magnetic resonance cholangiopancreatography (MRCP), magnetic resonance imaging (MRI), computed tomography (CT), endoscopic retrograde cholangiopancreatography (ERCP).

Performance: Pancreas divisum is an anatomic variation of pancreatic duct system with an incidence in general population of about 10%. Read More

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Direct visualization of anomalous pancreaticobiliary ductal union and pancreas divisum (with video).

Chi Hyuk Oh

Eur J Gastroenterol Hepatol 2021 04;33(4):596-598

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyung Hee University Hospital, Seoul, Republic of Korea.

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Idiopathic acute pancreatitis-A myth or reality? Role of endoscopic ultrasonography and magnetic resonance cholangiopancreatography in its diagnosis.

Indian J Gastroenterol 2021 02 6;40(1):22-29. Epub 2021 Feb 6.

Department of Gastroenterology, Sir Sunderlal Hospital, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, India.

Background: Around 10% to 30% patients with acute pancreatitis (AP) do not have a cause after the routine investigations, and are considered as having idiopathic acute pancreatitis (IAP). Establishing the etiology in such patients will prevent recurrences and evolution to chronic pancreatitis. Endoscopic ultrasonography (EUS) and magnetic resonance cholangiopancreatography (MRCP) characteristically are used to diagnose IAP when routine methods fail, but their exact role is not determined. Read More

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February 2021

Preoperative ERCP has no impact on islet yield following total pancreatectomy and islet autotransplantation (TPIAT): Results from the Prospective Observational Study of TPIAT (POST) cohort.

Pancreatology 2021 Jan 24;21(1):275-281. Epub 2020 Nov 24.

University of Minnesota Minneapolis, MN, USA.

Background And Aims: Many patients undergoing total pancreatectomy with islet autotransplant (TPIAT) for severe, refractory chronic pancreatitis or recurrent acute pancreatitis have a history of endoscopic retrograde cholangiopancreatography (ERCP). Using data from the multicenter POST (Prospective Observational Study of TPIAT) cohort, we aimed to determine clinical characteristics associated with ERCP and the effect of ERCP on islet yield.

Methods: Using data from 230 participants (11 centers), demographics, pancreatitis history, and imaging features were tested for association with ERCP procedures. Read More

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January 2021

Secretin-Enhanced MRCP: How and Why- Expert Panel Narrative Review.

AJR Am J Roentgenol 2021 05 11;216(5):1139-1149. Epub 2021 Mar 11.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N University Blvd, Rm 0663, Indianapolis, IN 46202.

Secretin-enhanced MRCP (S-MRCP) has advantages over standard MRCP for imaging of the pancreaticobiliary tree. Through the use of secretin to induce fluid production from the pancreas and leveraging of fluid-sensitive MRCP sequences, S-MRCP facilitates visualization of ductal anatomy, and the findings provide insight into pancreatic function, allowing radiologists to provide additional insight into a range of pancreatic conditions. This narrative review provides detailed information on the practical implementation of S-MRCP, including patient preparation, logistics of secretin administration, and dynamic secretin-enhanced MRCP acquisition. Read More

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Clinical Outcomes Following Therapeutic Endoscopic Retrograde Cholangiopancreatography in Children With Pancreas Divisum.

J Pediatr Gastroenterol Nutr 2021 02;72(2):300-305

Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center.

Objectives: Pancreas divisum (PD) is a risk factor in children for the development of acute pancreatitis. Endoscopic retrograde cholangiopancreatography (ERCP) with minor papilla endoscopic sphincterotomy (mPES) may be of clinical benefit, however, the clinical outcomes from endotherapy remain unclear. We sought to review the outcomes and safety of therapeutic ERCP in children with PD. Read More

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February 2021

Protein misfolding in combination with other risk factors in CEL-HYB1-mediated chronic pancreatitis.

Eur J Gastroenterol Hepatol 2021 06;33(6):839-843

The Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen.

Objectives: The hybrid allele of the carboxyl ester lipase gene (CEL-HYB1) is a genetic risk factor for chronic pancreatitis (CP) although the mechanism promoting disease development is largely unknown. Here, we aimed to clinically describe subjects carrying the CEL-HYB1 allele and to elucidate why the protein product is pathogenic by analyzing pancreatic secretions and cellular models.

Methods: Norwegian cases (n = 154) diagnosed with recurrent acute pancreatitis or CP were subjected to genetic screening by a CEL-HYB1-specific PCR assay followed by Sanger sequencing. Read More

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Bridging the Divisum: A Rare Case of Pancreaticopleural Fistula in the Setting of Complete Pancreatic Divisum Treated Endoscopically.

J Investig Med High Impact Case Rep 2020 Jan-Dec;8:2324709620965335

SUNY Upstate Medical University, Syracuse, NY, USA.

A pancreaticopleural fistula (PPF) is a rare complication of chronic pancreatitis that occurs either due to a pancreatic duct disruption or a pseudocyst extension. A pancreatic divisum, on the other hand, is a common anatomic variant of the pancreas that is rarely symptomatic. We describe a case of recurrent pleural effusion in a patient with a history of chronic pancreatitis. Read More

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Idiopathic recurrent acute pancreatitis in the context of pancreas divisum: A case report.

Radiol Case Rep 2020 Nov 10;15(11):2255-2258. Epub 2020 Sep 10.

The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, JHOC 3140B, 601 North Caroline St, Baltimore, MD 21287, USA.

Recurrent acute pancreatitis is characterized by frequent episodes of inflammation in the pancreas. The most common causes are alcohol abuse and gallstones but approximately 30% of cases are defined as idiopathic because initial evaluation fails to detect the etiology. In these patients, extensive laboratory and imaging evaluations usually lead to the uncovering of an occult biliary duct stone or sphincter of Oddi dysfunction as the main reason for frequent pancreatitis. Read More

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November 2020

Pancreatic divisum with chronic pancreatitis of the ventral pancreas.

ANZ J Surg 2021 03 10;91(3):E126-E127. Epub 2020 Jul 10.

Division of GI and HPB Surgery, Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

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Incidence and risk factors for post-ERCP pancreatitis in pancreas divisum patients without chronic pancreatitis.

Scand J Gastroenterol 2020 Jun 22;55(6):732-736. Epub 2020 Jun 22.

Digestive Endoscopy Center, Department of Gastroenterology, Changhai Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.

The studies on post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in pancreas divisum (PD) patients without chronic pancreatitis (CP) are rare. In this study, we aimed to evaluate the incidence of PEP in PD patients without CP and the risk and protective factors for PEP. Consecutive patients with symptomatic PD that underwent ERCP from January 2005 to December 2017 were retrospectively analyzed. Read More

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Complex Pancreaticobiliary Maljunction with Pancreas Divisum and Obstructive Pseudocyst.

J Clin Imaging Sci 2020 25;10:31. Epub 2020 May 25.

Departments of Radiology, Tripler Army Medical Center, 1 Jarrett White Rd., Honolulu, Hawaii, United States.

Pancreaticobiliary maljunction (PBM) is the congenital junction of the bile and pancreatic ducts into a common channel located anatomically outside of the duodenal wall. The complex type (Type D) is the rarest type and occurs in conjunction with other pancreaticobiliary anomalies. We present a case of complex PBM with pancreas divisum presenting as acute pancreatitis and obstructive symptoms secondary to a pancreatic pseudocyst. Read More

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Synchronous Periampullary Tumors in a Patient With Pancreas Divisum and Neurofibromatosis Type 1.

Front Genet 2020 28;11:395. Epub 2020 Apr 28.

Laboratório de Medicina Genômica, Centro de Pesquisa Experimental, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

Introduction: In this study, we describe for the first time a Neurofibromatosis type 1 patient with pancreas divisum, multiple periampullary tumors and germline pathogenic variants in and genes.

Case Report: A 62-year-old female NF1 patient presented with weakness, choluria, nausea, and diffuse abdominal pain to an emergency room service. Magnetic resonance imaging revealed an abdominal mass involving the periampullary region and pancreas divisum. Read More

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Role of magnetic resonance cholangiopancreatography (MRCP) in learning anatomical variations in pancreatic duct.

J Pak Med Assoc 2020 Mar;70(3):472-476

Department of Anatomy, United Medical & Dental College, affiliated by Jinnah Sindh Medical University, Karachi, Pakistan.

Objective: To assess the frequency of anatomical variations of pancreatic duct through magnetic resonance cholangiography pancreatography. .

Methods: The cross-sectional prospective study was conducted from May 2011 to December 2012 at the Department of Anatomy, Institute of Basic Medical Sciences (IBMS), Dow University of Health Sciences, Karachi, in collaboration with the Department of Radiology, Aga Khan University Hospital, Karachi. Read More

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Secretin Improves Visualization of Nondilated Pancreatic Ducts in Children Undergoing MRCP.

AJR Am J Roentgenol 2020 04 5;214(4):917-922. Epub 2020 Feb 5.

Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229.

The objective of our study was to assess whether secretin improves visualization of a nondilated pancreatic duct and whether it increases identification of variant duct anatomy on MRCP in pediatric patients. This study is a delayed retrospective review of MRCP images that were prospectively obtained of 50 volunteers without a history of pancreatic disease who ranged in age from 6 to 15 years old. MRCP images (coronal 3D fast recovery fast spin-echo [FSE] and coronal single-shot FSE fat-saturated sequences) obtained before and after secretin administration were separated for review by three radiologists (reviewers 1-3). Read More

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Mixed-type intraductal papillary mucinous neoplasm in a patient with pancreas divisum: pancreatoscopy through the Santorini duct with direct intraductal biopsy.

Gastrointest Endosc 2020 06 22;91(6):1398-1400. Epub 2020 Jan 22.

Gastroenterology and Endoscopy Unit, ARNAS Civico - Di Cristina, Benfratelli Hospital, Palermo, Italy.

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