897 results match your criteria Pancoast Tumor


Rev Port Cir Cardiotorac Vasc 2021 Apr 8;28(1):61-63. Epub 2021 Apr 8.

Thoracic Surgery Department, Centro Hospitalar Universitário Lisboa Norte, Portugal.

Pancoast tumours are defined as tumours arising from the upper lobe and invading the thoracic inlet,representing less than 5% of all lung cancers. Clinical features depend on the involved structures. For many years invasion of the spine was considered unresectable and fatal. Read More

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Pancoast Tumor as the Initial Presentation of a Metastatic Colon Adenocarcinoma.

Cureus 2021 Feb 16;13(2):e13371. Epub 2021 Feb 16.

Department of Internal Medicine, Centro Hospitalar Universitário São João, Porto, PRT.

A Pancoast tumor is a rare condition, representing 3% to 5% of all lung cancers. The particular location of these lesions leads to the invasion of structures in the thoracic inlet, causing a constellation of symptoms known as Pancoast-Tobias syndrome. Diagnosis can be challenging due to their low prevalence and the possibility of being asymptomatic. Read More

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February 2021

Pancoast-Tobias Syndrome: A Unique Presentation of Lung Cancer.

Cureus 2021 Feb 3;13(2):e13112. Epub 2021 Feb 3.

Internal Medicine, Saint Mary's Hospital, Waterbury, USA.

A 65-year-old man with 50 pack-year smoking history presented to the emergency department for evaluation of upper back and right shoulder pain secondary to a fall. Physical examination was notable for anisocoria with a constricted left pupil (miosis), mild ptosis of the left eyelid, and bilateral shoulder pain, right more than left, with both passive and active movements. Chest computed tomography identified a soft tissue mass at the left lung apex with extension into the pleural surface, associated with destructive osseous changes of the right scapula, adjacent ribs, and thoracic vertebral bodies. Read More

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February 2021

Pathologic complete response after neoadjuvant tislelizumab and chemotherapy for Pancoast tumor: A case report.

Thorac Cancer 2021 04 3;12(8):1256-1259. Epub 2021 Mar 3.

Department of Cardiothoracic Surgery, Zhongshan People's Hospital, Zhongshan, China.

A 60-year-old man was hospitalized because of numbness and weakness in the right upper limb. Magnetic resonance imaging revealed a large mass in the right upper lobe invading the right eighth cervical and first thoracic nerve root. Biopsy pathology confirmed primary lung adenocarcinoma with a clinical stage of cT4N0M0 IIIA, negative for anaplastic lymphoma kinase fusion gene and epidermal growth factor receptor mutations but positive for programmed death ligand 1 (3%). Read More

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Primary pulmonary angiosarcoma presenting as Pancoast tumor.

Asian Cardiovasc Thorac Ann 2021 Jan 12:218492320988456. Epub 2021 Jan 12.

Department of Thoracic Surgery, Gazi University, Ankara, Turkey.

A primary pulmonary angiosarcoma is an extremely rare entity with fewer than 30 cases reported in the literature. We found no reports of primary pulmonary angiosarcoma presenting as a Pancoast tumor. We describe a case of pulmonary angiosarcoma located in the right superior sulcus that was treated by surgery. Read More

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January 2021

Superior Vena Cava Syndrome Due to Thymic Carcinoma.

Cureus 2020 Nov 24;12(11):e11670. Epub 2020 Nov 24.

General Surgery, Hospital Regional de Alta Especialidad del Bajío, León, MEX.

The superior vena cava syndrome (SVCS) is caused by a mechanical obstruction; 90% are of neoplasic etiology (lung cancer (LC) and non-Hodgkin lymphoma (NHL) mostly), epithelial neoplasms of the thymus (NET) is a rare cause, thymic carcinoma (TC) causing less than 1% of cases. A 56-year-old male presented with a four-month history of dyspnea, dysphonia, facial and cervical edema and bilateral cervical lymphadenopathy. The tomography showed bilateral, mediastinal, retroperitoneal lymphadenopathies, and obstruction of the internal jugular vein, right apical pulmonary nodules. Read More

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November 2020

Three-stage approach to resection of left pancoast tumour with spinal and major vessel involvement.

J Surg Case Rep 2020 Dec 14;2020(12):rjaa384. Epub 2020 Dec 14.

Division of Thoracic Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

Here we describe the successful outcome of a complex and challenging resection of a left-sided pancoast tumour involving the left subclavian artery and vertebral bodies. The resection was performed following neoadjuvant chemoradiotherapy in a multi-staged fashion involving multiple teams including thoracic surgery, plastic surgery, neurosurgery and vascular surgery. Each operation was less than 6 h, without complication, and the patient was discharged within 1 week of each procedure. Read More

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December 2020

Estimated direct costs of non-small cell lung cancer by stage at diagnosis and disease management phase: A whole-disease model.

Thorac Cancer 2021 01 21;12(1):13-20. Epub 2020 Nov 21.

Medical Oncology 2, Istituto Oncologico Veneto IRCCS, Padova, Italy.

Background: Non-small cell lung cancer (NSCLC) is the first cause of cancer-related death among men and the second among women worldwide. It also poses an economic threat to the sustainability of healthcare services. This study estimated the direct costs of care for patients with NSCLC by stage at diagnosis, and management phase of pathway recommended in local and international guidelines. Read More

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January 2021

Unilateral autoimmune inner ear disease in a patient with lung cancer treated with nivolumab.

Oxf Med Case Reports 2020 Sep 22;2020(9):omaa077. Epub 2020 Sep 22.

Queensland University of Technology, Faculty of Health, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Cancer and Ageing Research Program, Brisbane, Australia.

A 69-year-old male presented with early stage non-small cell lung cancer in 2016. The tumor was resected; however, the patient experienced recurrence 2 years later and subsequently received paclitaxel/carboplatin concurrently with radiotherapy. Within weeks of completing this treatment, he developed a symptomatic pancoast tumor secondary to disease progression and commenced second line nivolumab. Read More

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September 2020

A clinico-epidemiological, pathological, and molecular study of lung cancer in Northwestern India.

J Cancer Res Ther 2020 Jul-Sep;16(4):771-779

Department of Medical Oncology, Army Hospital Research and Referral, New Delhi, India.

Introduction: Lung cancer is the most common malignant disease and is the topmost cause of cancer deaths in the world across all age groups and in both sexes. It is the most common cause of cancer deaths in developed countries and is also rising at an alarming rate in the developing countries.

Objective: The present study was undertaken to explore the clinicopathological and molecular profile of bronchogenic carcinoma in northwestern population of India. Read More

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November 2020

Pancoast Tumor: The Overlooked Etiology of Shoulder Pain in Smokers.

Am J Case Rep 2020 Sep 11;21:e926643. Epub 2020 Sep 11.

Department of Family Medicine, King Fahad Specialist Hospital, Dammam, Saudi Arabia.

BACKGROUND Shoulder pain is a common complaint in general practice and typically has an orthopedic or rheumatological etiology. However, it may be the presenting symptom of a serious underlying condition, such as lung cancer. CASE REPORT A 60-year-old man with a 30 pack-year history of smoking presented with worsening right shoulder pain over the last 6 months. Read More

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September 2020

Primary plasma cell leukemia mimicking a Pancoast tumor.

Am J Hematol 2020 11 3;95(11):1430-1431. Epub 2020 Oct 3.

Department of Pathology, Maasstad Hospital, Rotterdam, The Netherlands.

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November 2020

[Do we inspecting the patient face who has shoulder pain?]

Agri 2020 Apr;32(2):109-112

Division of Algology, Department of Neurology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.

A Pancoast or superior sulcus tumor is a rare, bronchogenic carcinoma. In the early period, shoulder pain is the most common symptom. In this case, the patient had presented with complaints of shoulder and arm pain at other outpatient clinics and was examined primarily for musculoskeletal causes and radiculopathy. Read More

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A minimally invasive and safe surgical approach to resect anterior superior sulcus tumors.

Int J Surg Case Rep 2020 28;68:148-150. Epub 2020 Feb 28.

Thoracic Surgery, Kokura Memorial Hospital, Kitakyushu-shi, Japan.

Introduction: Superior sulcus tumors (SSTs) are a wide range of tumors invading a section of the apical chest wall called the thoracic inlet. The unique characteristics of SSTs lie in the anatomy of the region where these tumors occur. For this reason, a surgical approach to treating these tumors is technically demanding, and complete resection may be difficult to accomplish. Read More

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February 2020

Significant prognostic determinants in lung cancers of the superior sulcus: comparable analysis of resected and unresected cases.

Gen Thorac Cardiovasc Surg 2020 Aug 3;68(8):801-811. Epub 2020 Mar 3.

Department of Thoracic Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

Objective: In this study, we aimed to identify prognostic determinants and to comparably analyze clinical features of patients with both resected and unresected superior sulcus tumors (SSTs).

Methods: The data of 56 patients who underwent any treatment for an SST from 2004 through 2016 in our hospital were reviewed. Overall survival (OS) rates were estimated using the Kaplan-Meier method. Read More

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T1 Erector Spinae Plane Block Catheter As a Novel Treatment Modality for Pancoast Tumor Pain.

Cureus 2019 Nov 7;11(11):e6092. Epub 2019 Nov 7.

Anesthesiology, University of Alabama, Birmingham, USA.

Pancoast tumors are non-small cell lung tumors, which can invade the ribs, vertebrae, sympathetic ganglia and brachial plexus. In this study, a patient with right-sided Pancoast tumor presented with intractable chronic pain on the right neck, upper extremity and chest wall. The chronic pain associated with Pancoast tumor, which was difficult to treat with opioids and other medications, was effectively treated with a high-thoracic erector spinae plane block (ESPB). Read More

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November 2019

Neoadjuvant therapy with vemurafenib in Horner's syndrome as a very rare first diagnosis of a malignant melanoma of unknown primary.

J Dtsch Dermatol Ges 2020 Jan 19;18(1):47-49. Epub 2019 Nov 19.

Department of Dermatology, Venereology and Allergology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.

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January 2020

Harlequin sign in Pancoast tumor.

Curr Probl Cancer 2020 04 1;44(2):100506. Epub 2019 Nov 1.

Division of Hematology and Medical Oncology, Department of Medicine, University of Louisville, Louisville, Kentucky. Electronic address:

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Superior sulcus tumor disguised as cervical radiculopathy with metastasis to brachial plexus.

Proc (Bayl Univ Med Cent) 2019 Oct 20;32(4):582-583. Epub 2019 Aug 20.

Department of Orthopedic Surgery, Baylor University Medical CenterDallasTexas.

A 74-year-old man presented to an orthopedic spine surgeon with signs and symptoms consistent with cervical radiculopathy. Investigation revealed metastasis of a Pancoast tumor to the patient's brachial plexus. A year after initial diagnosis, the patient achieved full neurological function of his left arm. Read More

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October 2019

[Surgical Treatment for Apical Invading Lung Cancer].

Kyobu Geka 2019 Sep;72(10):840-844

Department of General Thoracic Surgery, Dokkyo Medical University, Tochigi, Japan.

The apical invading lung cancer is the tumor infiltrating to the thoracic inlet, in other words, the 1st rib or the higher chest wall. Tumor arising in the posterior apex is invasive to the vertebral body, the sympathetic trunk, and the brachial plexus. Pancoast tumor is well known with typical triads, which is invasive to the sympathetic trunk and the brachial plexus in the posterior apex of the lung. Read More

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September 2019

Huge maxillary metastasis of an aggressive Pancoast tumor -A case report.

Caspian J Intern Med 2019 ;10(3):351-355

Student. Research Committee, Babol University of Medical Science, Babol, Iran.

Background: Metastatic carcinomas to the upper jaw region are very rare and unfortunately occur in advanced stages of malignancies. Pancoast tumor is a challenging subset of lung carcinoma commonly followed by distant metastasis. Since the metastatic lesion of our patient was very huge and unusual, we decided to report the case. Read More

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January 2019

Pancoast tumour: current therapeutic options.

Clin Ter 2019 Jul-Aug;170(4):e291-e294

Department of Surgical, Oncological and Stomatological Disciplines, University of Palermo.

Background: Pancoast's syndrome is caused by malignant neoplasm of superior sulcus of the lung which produces destructive lesions of thoracic inlet and comes along with the involvement of brachial plexus and stellate ganglion. Computed tomography (CT) or magnetic resonance imaging (MRI) scans can detect early lesions otherwise missed by routine radiographs and can also define the local extent or metastatic progression of the disease. Protocols involving combinations of irradiation, chemotherapy, and surgery are currently being under investigation to determine the best management. Read More

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October 2019

The new 8th TNM staging system of lung cancer and its potential imaging interpretation pitfalls and limitations with CT image demonstrations.

Diagn Interv Radiol 2019 Jul;25(4):270-279

Department of Radiology, China Medical University Hospital, Taichung, Taiwan;School of Chinese Medicine, China Medical University, Taichung, Taiwan.

The tumor, node, metastasis (TNM) staging system approved by International Association for the Study of Lung Cancer (IASLC) and the American Joint Committee on Cancer (AJCC) to stage lung cancer was recently revised. The latest revision is the 8th edition published in January, 2017. This new edition made some important changes to the previous edition, including modification of the T classification based on 1 cm increment, downstage of T descriptor including endobronchial tumor disregarding its distance from carina (T2), merging total and partial atelectasis/pneumonitis into the same T category (T2), upstage diaphragmatic invasion to T4, new classification concept of adenocarcinoma in situ and minimally invasive adenocarcinoma for pure and part-solid ground-glass nodules, and further division of extrathoracic metastasis into M1b and M1c based on the number and sites of extrathoracic metastases. Read More

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An quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting.

Clin Transl Radiat Oncol 2019 Feb 6;15:83-92. Epub 2019 Jan 6.

Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, TX 77030, USA.

Introduction: Target delineation variability is a significant technical impediment in multi-institutional trials which employ intensity modulated radiotherapy (IMRT), as there is a real potential for clinically meaningful variances that can impact the outcomes in clinical trials. The goal of this study is to determine the variability of target delineation among participants from different institutions as part of Southwest Oncology Group (SWOG) Radiotherapy Committee's multi-institutional quality assurance study in patients with Pancoast tumors as a "dry run" for trial implementation.

Methods: CT simulation scans were acquired from four patients with Pancoast tumor. Read More

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February 2019

Horner's Syndrome as Initial Manifestation of Possible Brachial Plexopathy Neurolymphomatosis.

Front Neurol 2019 22;10. Epub 2019 Jan 22.

Department of Neurology, Ohio State University Wexner Medical Center, Columbus, OH, United States.

Horner's syndrome is an established clinical finding unique to neoplastic brachial plexopathy. We present the case of a patient who developed Horner's syndrome as the first manifestation of neurolymphomatosis (NL) of the brachial plexus that did not have the usually associated bulky adenopathy/Pancoast syndrome phenotype. We discuss the clinical utility of Horner's syndrome with regards to brachial plexopathy of indeterminate etiology, as well as the utility of other diagnostic modalities in NL. Read More

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January 2019

Pancoast tumour presenting as shoulder pain with Horner's syndrome.

BMJ Case Rep 2019 Jan 24;12(1). Epub 2019 Jan 24.

Emergency Department, Guy's and Saint Thomas' NHS Foundation Trust, London, UK.

A 54-year-old man presented to the emergency department with a 4-week history of right shoulder pain radiating down his arm, with some associated sensory loss. Further questioning and examination in the department revealed a classical Horner's syndrome; miosis, partial ptosis and hemifacial anhidrosis. An initial chest X-ray was deemed to be unremarkable; however, further review by a radiologist noted asymmetrical right apical thickening. Read More

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January 2019

Esophageal ultrasound with ultrasound bronchoscope (EUS-B) guided left adrenal biopsy: Case report with review of literature.

Respir Med Case Rep 2019 20;26:154-156. Epub 2018 Dec 20.

Department of Pulmonary Medicine, Santa Maria degli Angeli di Pordenone, Italy.

A 45-year old man, chronic smoker with a pancoast tumor due to squamous cell carcinoma has been described. The initial diagnosis of lung carcinoma was based on a scant tissue so the exact cell typing was not possible. The initial treatment consisted of platinum based chemotherapy and radiotherapy. Read More

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December 2018

Pancoast's syndrome caused by lymph node metastasis from breast cancer.

BMJ Case Rep 2018 Nov 28;11(1). Epub 2018 Nov 28.

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University, Chieti, Italy.

Pancoast's syndrome may be the result of neoplastic, inflammatory or infectious disease. We report an unusual case of Pancoast's syndrome in a patient with metastatic breast cancer. A 54-year-old woman, affected by metastatic breast cancer, presented for severe shoulder pain, paraesthesia and numbness in the right arm. Read More

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November 2018