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Asian Spine J 2022 Jun 3. Epub 2022 Jun 3.

Division of Neurosurgery, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, QC, Canada.

Study Design: Retrospective cohort study.

Purpose: This study aimed to evaluate the outcomes of patients who had T4 Pancoast tumors invading the spine and underwent en bloc resection and spinal stabilization through a single-stage posterior approach.

Overview Of Literature: Surgical resection for Pancoast tumors affecting the spine has been successfully performed in two stages involving spinal reconstruction and tumor resection. Read More

Cureus 2022 Apr 7;14(4):x16. Epub 2022 Apr 7.

Internal Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.

J Small Anim Pract 2022 Jun 16;63(6):493. Epub 2022 Mar 16.

Veterinary Pathology Diagnostic Centre, Department of Biomedical Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

J Med Case Rep 2022 Mar 15;16(1):109. Epub 2022 Mar 15.

Department of Neurology, Howard University Hospital, Washington, DC, USA.

Background: Pancoast tumors represent a unique subset of lung cancers wherein a primary neoplasm arises in the lung's apex and invades the surrounding soft tissues. One of the main challenges in the diagnosis and treatment of these apical lung cancers is that they are usually not visualized on initial chest x-ray and, by the time the patient presents with symptoms, the tumor has almost always invaded nearby structures.

Case Presentation: Herein we report a case of a 58-year-old nonsmoking African American male who presented to the neurology clinic with a history of multiple chronic joint pains. Read More

JNMA J Nepal Med Assoc 2022 Feb 15;60(246):211-213. Epub 2022 Feb 15.

Department of Pulmonary, Critical Care and Sleep Medicine, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.

Small cell lung cancer mostly arises centrally in the large bronchi. The literature search revealed very limited cases of small cell lung cancer arising at the upper part of the pulmonary sulcus near the thoracic inlet as superior sulcus tumor and also manifesting with typical Pancoast syndrome. We report a case of a 71 years old male patient, presenting with features of Pancoast syndrome including Horner's syndrome with completed three cycles of chemotherapy resulting in partial response which concludes that small cell lung carcinoma has to be considered despite the clinical findings like pancoast syndrome. Read More

Interact Cardiovasc Thorac Surg 2022 01;34(1):74-80

Department of Thoracic and Vascular Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.

Objectives: This article aims to evaluate the feasibility and safety of a hybrid video-assisted thoracic surgery (VATS) approach to achieve en bloc lobectomy and spinal resection for non-small-cell lung cancer (NSCLC).

Methods: Between October 2015 and November 2020, 10 patients underwent VATS anatomical lobectomy and en bloc chest wall and spinal resection through a limited posterior midline incision as a single operation for T4 (vertebral involvement) lung cancer. Nine patients had Pancoast syndrome without vascular involvement and 1 patient had NSCLC of the right lower lobe with invasion of T9 and T10. Read More

Cureus 2021 Nov 9;13(11):e19418. Epub 2021 Nov 9.

Internal Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.

Musculoskeletal disorders represent a major public health problem and they are frequently managed in primary care centers. Shoulder pain is a frequent musculoskeletal complaint and it can result from intrinsic disorders of the shoulder or referred pain. We present the case of a 24-year-old woman who presented to the family medicine clinic complaining of left shoulder pain for three months duration. Read More

Interact Cardiovasc Thorac Surg 2021 Jul 30. Epub 2021 Jul 30.

Department of Thoracic and Vascular Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.

Objectives: This article aims to evaluate the feasibility and safety of a hybrid video-assisted thoracic surgery (VATS) approach to achieve en bloc lobectomy and spinal resection for non-small-cell lung cancer (NSCLC).

Methods: Between October 2015 and November 2020, 10 patients underwent VATS anatomical lobectomy and en bloc chest wall and spinal resection through a limited posterior midline incision as a single operation for T4 (vertebral involvement) lung cancer. Nine patients had Pancoast syndrome without vascular involvement and 1 patient had NSCLC of the right lower lobe with invasion of T9 and T10. Read More

Rev Prat 2021 Jan;71(1):68

"Service de neuroradiologie, Hôpital des spécialités, CHU Ibn Sina, Université Mohamed V, Faculté de médecine et de pharmacie, Rabat, Maroc".

J Mycol Med 2021 Sep 12;31(3):101154. Epub 2021 May 12.

Institute of Neurological Sciences, CARE Hospital, Banjara hills, Hyderabad, Telangana, India.

Pancoast's syndrome and subclavian arteritis are rarely caused by Aspergillus sp. . Here we report a case of a 22-yr-old, immunocompetent male who presented with fever, weight loss, right-sided facial anhidrosis and hand weakness of six months duration. Read More

Eur Radiol 2021 Dec 15;31(12):8991-8999. Epub 2021 May 15.

Department of Radiology, Gustave Roussy Cancer Campus, 114 Rue Edouard Vaillant, Villejuif, 94800, Paris, France.

Objectives: Vertebral invasion is a key prognostic factor and a critical aspect of surgical planning for superior sulcus tumors. This study aims to further evaluate MRI features of vertebral invasion in order to distinguish it from reactive inflammatory changes.

Methods: Between 2000 and 2016, a retrospective study was performed at a single institution. Read More

Port J Card Thorac Vasc Surg 2021 Apr 8;28(1):61-63. Epub 2021 Apr 8.

Thoracic Surgery Department, Centro Hospitalar Universitário Lisboa Norte, Portugal.

Pancoast tumours are defined as tumours arising from the upper lobe and invading the thoracic inlet,representing less than 5% of all lung cancers. Clinical features depend on the involved structures. For many years invasion of the spine was considered unresectable and fatal. Read More

Cureus 2021 Feb 16;13(2):e13371. Epub 2021 Feb 16.

Department of Internal Medicine, Centro Hospitalar Universitário São João, Porto, PRT.

A Pancoast tumor is a rare condition, representing 3% to 5% of all lung cancers. The particular location of these lesions leads to the invasion of structures in the thoracic inlet, causing a constellation of symptoms known as Pancoast-Tobias syndrome. Diagnosis can be challenging due to their low prevalence and the possibility of being asymptomatic. Read More

Cureus 2021 Feb 3;13(2):e13112. Epub 2021 Feb 3.

Internal Medicine, Saint Mary's Hospital, Waterbury, USA.

A 65-year-old man with 50 pack-year smoking history presented to the emergency department for evaluation of upper back and right shoulder pain secondary to a fall. Physical examination was notable for anisocoria with a constricted left pupil (miosis), mild ptosis of the left eyelid, and bilateral shoulder pain, right more than left, with both passive and active movements. Chest computed tomography identified a soft tissue mass at the left lung apex with extension into the pleural surface, associated with destructive osseous changes of the right scapula, adjacent ribs, and thoracic vertebral bodies. Read More

Thorac Cancer 2021 04 3;12(8):1256-1259. Epub 2021 Mar 3.

Department of Cardiothoracic Surgery, Zhongshan People's Hospital, Zhongshan, China.

A 60-year-old man was hospitalized because of numbness and weakness in the right upper limb. Magnetic resonance imaging revealed a large mass in the right upper lobe invading the right eighth cervical and first thoracic nerve root. Biopsy pathology confirmed primary lung adenocarcinoma with a clinical stage of cT4N0M0 IIIA, negative for anaplastic lymphoma kinase fusion gene and epidermal growth factor receptor mutations but positive for programmed death ligand 1 (3%). Read More

Asian Cardiovasc Thorac Ann 2021 Jun 12;29(5):434-437. Epub 2021 Jan 12.

Department of Thoracic Surgery, Gazi University, Ankara, Turkey.

A primary pulmonary angiosarcoma is an extremely rare entity with fewer than 30 cases reported in the literature. We found no reports of primary pulmonary angiosarcoma presenting as a Pancoast tumor. We describe a case of pulmonary angiosarcoma located in the right superior sulcus that was treated by surgery. Read More

Cureus 2020 Nov 24;12(11):e11670. Epub 2020 Nov 24.

General Surgery, Hospital Regional de Alta Especialidad del Bajío, León, MEX.

The superior vena cava syndrome (SVCS) is caused by a mechanical obstruction; 90% are of neoplasic etiology (lung cancer (LC) and non-Hodgkin lymphoma (NHL) mostly), epithelial neoplasms of the thymus (NET) is a rare cause, thymic carcinoma (TC) causing less than 1% of cases. A 56-year-old male presented with a four-month history of dyspnea, dysphonia, facial and cervical edema and bilateral cervical lymphadenopathy. The tomography showed bilateral, mediastinal, retroperitoneal lymphadenopathies, and obstruction of the internal jugular vein, right apical pulmonary nodules. Read More

J Cancer Res Ther 2020 Jul-Sep;16(4):771-779

Department of Medical Oncology, Army Hospital Research and Referral, New Delhi, India.

Introduction: Lung cancer is the most common malignant disease and is the topmost cause of cancer deaths in the world across all age groups and in both sexes. It is the most common cause of cancer deaths in developed countries and is also rising at an alarming rate in the developing countries.

Objective: The present study was undertaken to explore the clinicopathological and molecular profile of bronchogenic carcinoma in northwestern population of India. Read More

Am J Case Rep 2020 Sep 11;21:e926643. Epub 2020 Sep 11.

Department of Family Medicine, King Fahad Specialist Hospital, Dammam, Saudi Arabia.

BACKGROUND Shoulder pain is a common complaint in general practice and typically has an orthopedic or rheumatological etiology. However, it may be the presenting symptom of a serious underlying condition, such as lung cancer. CASE REPORT A 60-year-old man with a 30 pack-year history of smoking presented with worsening right shoulder pain over the last 6 months. Read More

Am J Hematol 2020 11 3;95(11):1430-1431. Epub 2020 Oct 3.

Department of Pathology, Maasstad Hospital, Rotterdam, The Netherlands.

QJM 2021 05;114(3):215-216

Barnet Hospital, Royal Free London NHS Foundation Trust, Wellhouse Lane, Barnet, EN5 3DJ, UK.

Agri 2020 Apr;32(2):109-112

Division of Algology, Department of Neurology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.

A Pancoast or superior sulcus tumor is a rare, bronchogenic carcinoma. In the early period, shoulder pain is the most common symptom. In this case, the patient had presented with complaints of shoulder and arm pain at other outpatient clinics and was examined primarily for musculoskeletal causes and radiculopathy. Read More

Gen Thorac Cardiovasc Surg 2020 Aug 3;68(8):801-811. Epub 2020 Mar 3.

Department of Thoracic Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

Objective: In this study, we aimed to identify prognostic determinants and to comparably analyze clinical features of patients with both resected and unresected superior sulcus tumors (SSTs).

Methods: The data of 56 patients who underwent any treatment for an SST from 2004 through 2016 in our hospital were reviewed. Overall survival (OS) rates were estimated using the Kaplan-Meier method. Read More

J Dtsch Dermatol Ges 2020 Jan 19;18(1):47-49. Epub 2019 Nov 19.

Department of Dermatology, Venereology and Allergology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.

Curr Probl Cancer 2020 04 1;44(2):100506. Epub 2019 Nov 1.

Division of Hematology and Medical Oncology, Department of Medicine, University of Louisville, Louisville, Kentucky. Electronic address:

Kyobu Geka 2019 Sep;72(10):840-844

Department of General Thoracic Surgery, Dokkyo Medical University, Tochigi, Japan.

The apical invading lung cancer is the tumor infiltrating to the thoracic inlet, in other words, the 1st rib or the higher chest wall. Tumor arising in the posterior apex is invasive to the vertebral body, the sympathetic trunk, and the brachial plexus. Pancoast tumor is well known with typical triads, which is invasive to the sympathetic trunk and the brachial plexus in the posterior apex of the lung. Read More

Clin Ter 2019 Jul-Aug;170(4):e291-e294

Department of Surgical, Oncological and Stomatological Disciplines, University of Palermo.

Background: Pancoast's syndrome is caused by malignant neoplasm of superior sulcus of the lung which produces destructive lesions of thoracic inlet and comes along with the involvement of brachial plexus and stellate ganglion. Computed tomography (CT) or magnetic resonance imaging (MRI) scans can detect early lesions otherwise missed by routine radiographs and can also define the local extent or metastatic progression of the disease. Protocols involving combinations of irradiation, chemotherapy, and surgery are currently being under investigation to determine the best management. Read More

Tidsskr Nor Laegeforen 2019 03 11;139(5). Epub 2019 Mar 11.

Front Neurol 2019 22;10. Epub 2019 Jan 22.

Department of Neurology, Ohio State University Wexner Medical Center, Columbus, OH, United States.

Horner's syndrome is an established clinical finding unique to neoplastic brachial plexopathy. We present the case of a patient who developed Horner's syndrome as the first manifestation of neurolymphomatosis (NL) of the brachial plexus that did not have the usually associated bulky adenopathy/Pancoast syndrome phenotype. We discuss the clinical utility of Horner's syndrome with regards to brachial plexopathy of indeterminate etiology, as well as the utility of other diagnostic modalities in NL. Read More