88,463 results match your criteria Palliative Care in the Acute Care Setting


Early impact of pulmonary stereotactic fractionated body radiotherapy (SBRT) on Quality of Life (QoL): Benefit for patients with low initial scores (STRIPE trial).

J Thorac Oncol 2018 Dec 3. Epub 2018 Dec 3.

Department of Radiation Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Germany; German Cancer Consortium (DKTK) Partner Site Freiburg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany.

Introduction: Quality of life (QoL) of comorbid patients with pulmonary malignancies is a key issue in considering stereotactic fractionated body radiotherapy (SBRT) indication. This study investigates the early impact of SBRT on QoL.

Methods: 100 patients with pulmonary lesions were treated with SBRT from 02/2011 to 11/2014 within the prospective, monocenter, phase II STRIPE trial. Read More

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December 2018
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Pain characterization and response to palliative care in dogs with naturally-occurring appendicular osteosarcoma: An open label clinical trial.

PLoS One 2018 6;13(12):e0207200. Epub 2018 Dec 6.

GREPAQ (Groupe de recherche en pharmacologie animale du Québec), Department of biomedical sciences, Faculty of Veterinary Medicine, Université de Montréal, Saint-Hyacinthe, Quebec, Canada.

This study aimed to characterize bone cancer pain (quantitative sensory testing (QST), stance asymmetry index, actimetry, scores of pain and quality of life (QoL)) in dogs with appendicular osteosarcoma (OSA), and to evaluate a stepwise palliative analgesic treatment. The pain profile of thirteen client-owned dogs with OSA was compared with seven healthy dogs. Dogs with OSA were then enrolled in a prospective, open-label, clinical trial. Read More

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December 2018

Treatment outcomes of pancreatic cancer in the elderly - literature review.

Folia Med Cracov 2018 ;58(3):49-66

3rd Department of General, Oncological and Geriatric Surgery of Jagiellonian University School of Medicine, Prądnicka 35-37, Kraków, Poland.

Background: The older population is very heterogeneous with regard to the co-morbidityand the physical reserve. This can result in unacceptably high postoperative complications rates. Therefore, the aim of the study was to review the literature regarding the outcomes of older patients treated for pancreatic cancer, including the usage of minimal invasive techniques. Read More

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January 2018

Supportive Care Network: Evaluation of Its Impact on the Performance of a Urology Department.

Acta Med Port 2018 Nov 30;31(11):656-660. Epub 2018 Nov 30.

Urology and Renal Transplantation Department. Coimbra University Hospital Center. Coimbra. Portugal.

Introduction: Hospitals are dealing with patients who may have clinical discharge but cannot return to their home due to non-medical issues.

Material And Methods: Cross-sectional analysis of all the cases referred to the Integrated Care Network during the year 2016. Evaluation of waiting times, typology, reason for referral and clinical parameters. Read More

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November 2018
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The blueprint for palliative care provision.

Authors:
Brian Nyatanga

Br J Community Nurs 2018 Dec;23(12):618

Academic Lead for Centre for Palliative Care, University of Worcester.

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December 2018

Planning for more palliative care.

Authors:
Alison While

Br J Community Nurs 2018 Dec;23(12):622

Emeritus Professor of Community Nursing, King's College London, Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, and Fellow of the Queen's Nursing Institute.

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December 2018

Second infield re-irradiation with a resulting cumulative equivalent dose (EQD2 ) of >180 Gy for patients with recurrent head and neck cancer.

Head Neck 2018 Dec 6. Epub 2018 Dec 6.

Department of Radiation Oncology, Johann Wolfgang Goethe University, Frankfurt, Germany.

Background: For locally recurrent head and neck cancer, re-irradiation with modern techniques like stereotactic body radiotherapy is a promising, possibly curative alternative to palliative systemic therapy.

Methods: We report on 1 patient with nasopharyngeal carcinoma (NPC) and 1 patient with cutaneous squamous cell carcinoma (SCC). Both patients received full dose primary treatment (>66 Gy, EQD2), full dose re-irradiation (>50 Gy, EQD2), and a second course of re-irradiation via robotic radiosurgery (CyberKnife) for a second local recurrence. Read More

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December 2018
2 Reads

Evidence of palliative care stigma: The role of negative stereotypes in preventing willingness to use palliative care.

Palliat Support Care 2018 Dec 6:1-7. Epub 2018 Dec 6.

Department of Psychology,California State University San Bernardino,San Bernardino, CA.

Objective: Although palliative care is critical to managing symptoms, pain, and transitions to end-of-life care among those facing serious or chronic illness, it is often underused, which may be due to stigma associated with palliative care representing giving up fighting one's illness. The goal of the present studies was to test the theoretical framework of stigma within the context of palliative care to inform future work on intervention development that addresses potential barriers to palliative care utilization.

Method: In study 1, participants (n = 152) had an oncologist describe two treatment options to a terminally ill cancer patient: (1) palliative care and (2) chemotherapy. Read More

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December 2018

Radiotherapy in Patients with Mycosis Fungoides and Central Nervous System Involvement.

Case Rep Oncol 2018 Sep-Dec;11(3):721-728. Epub 2018 Nov 12.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Background: Involvement of the central nervous system (CNS) by mycosis fungoides (MF) is rare; however, it portends a poor prognosis. While aggressive multimodality therapy may improve outcomes, the role of radiation therapy (RT) is not well defined.

Objectives: We sought to explore the efficacy of RT in the management of CNS involvement by MF. Read More

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November 2018

Chair ICO/UVIC-UCC of palliative care at the University of Vic - Central University of Catalonia: an innovative multidisciplinary model of education, research and knowledge transfer.

BMJ Support Palliat Care 2018 Dec 5. Epub 2018 Dec 5.

Catalan Institute of Oncology, Barcelona, Spain.

Objectives: Generation and dissemination of knowledge is a relevant challenge of palliative care (PC). The Chair Catalan Institute of Oncology (ICO)/University of Vic (UVIC) of Palliative Care (CPC) was founded in 2012, as a joint project of the ICO and the University of Vic/Central of Catalonia to promote the development of PC with public health and community-oriented vision and academic perspectives. The initiative brought together professionals from a wide range of disciplines (PC, geriatrics, oncology, primary care and policy) and became the first chair of PC in Spain. Read More

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December 2018
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Bereaved Parents More Satisfied With the Care Given to Their Child With Severe Spinal Muscular Atrophy Than Nonbereaved.

J Child Neurol 2018 Dec 5:883073818811544. Epub 2018 Dec 5.

1 Ersta Sköndal Bräcke University College, Department of Health Care Sciences, Palliative Research Centre, Stockholm, Sweden.

Background And Aims:: Children with severe spinal muscular atrophy have complex care needs due to progressive muscle weakness, eventually leading to respiratory failure. To design a care system adapted to families' needs, more knowledge about parents' experience of care and its coordination between settings is required. This study explores (1) whether parents felt that health professionals took every opportunity to help the child feel as good as possible, (2) parents' satisfaction with various care settings, and (3) parents' satisfaction with coordination between settings. Read More

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December 2018

What Does Death Preparedness Mean for Family Caregivers of Persons With Dementia?

Am J Hosp Palliat Care 2018 Dec 5:1049909118814240. Epub 2018 Dec 5.

1 Faculty of Health Sciences, School of Nursing, McMaster University, Hamilton, Ontario, Canada.

Purpose:: The purpose of this study was to clarify the concept of death preparedness for family caregivers in dementia. Conceptualization was required to support the assessment, promotion, and operationalization (ie, measurement) of death preparedness through palliative care interventions such as advance care planning.

Methods:: Rodgers evolutionary method of concept analysis was selected to guide this study because of the dynamic nature of death preparedness influenced by context, setting, and time. Read More

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December 2018

The effect of residential aged care size, ownership model and multi-chain affiliation on resident comfort and symptom management at the end of life.

J Pain Symptom Manage 2018 Nov 30. Epub 2018 Nov 30.

School of Nursing, Faculty of Medical and Health Sciences University of Auckland, Auckland, New Zealand.

Context: In most resource-rich countries, a large and growing proportion of older adults with complex needs will die while in a Residential Aged Care (RAC) facility.

Objectives: This study describes the impact of facility size (small/large), ownership model (profit/non-profit) and provider (independent/chain) on resident comfort and symptom management as reported by RAC staff.

Methods: This retrospective 'after-death' study collected data decedent resident data from a subsample of 51 hospital-level residential aged care facilities in New Zealand. Read More

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November 2018

Pain response rates after conventional radiation therapy for bone metastases in prospective non-randomized studies: A systematic review.

Pract Radiat Oncol 2018 Nov 30. Epub 2018 Nov 30.

Department of Radiation Oncology, Kumamoto University Hospital, Kumamoto, Japan.

Purpose: To determine pain response rates following conventional radiation therapy for painful bone metastases in prospective non-randomized studies, which better reflect daily practice than randomized controlled trials.

Methods: A literature search was conducted in PubMed and Scopus for articles published from 2002 to 2018. We only included articles in which pain response following radiation therapy was assessed using the International Consensus Endpoint initially published in 2002, or that updated in 2012. Read More

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November 2018
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Intravenous Lidocaine Administered as Twice Daily Bolus and Continuous Infusion for Intractable Cancer Pain and Wound Care Pain.

J Palliat Med 2018 Dec 1. Epub 2018 Dec 1.

3 Spectrum Health Medical Group , Palliative Care Medicine, Grand Rapids, Michigan.

Introduction: Intravenous lidocaine is an option for intractable pain caused by advancing cancer and wound care. We report a case of intractable cancer pain and wound care pain managed with concurrent use of lidocaine administered as a twice daily intravenous bolus in addition to continuous intravenous infusion.

Case Description: A 31-year-old male with rapidly progressing locally advanced squamous cell cancer affecting the gluteal area developed extensive painful and purulent ulcerating wounds affecting the coccyx, superior gluteal cleft, and buttocks. Read More

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December 2018
2 Reads

Living Wills: One Part of the Advance Care Planning Puzzle.

J Am Geriatr Soc 2018 Dec 3. Epub 2018 Dec 3.

UCSF School of Nursing, Department of Community Health Systems, San Francisco, California.

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December 2018

Unmet social support needs among older adults with cancer.

Cancer 2018 Dec 3. Epub 2018 Dec 3.

Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, Alabama.

Background: Adequate social support for older adults is necessary to maintain quality of life and reduce mortality and morbidity. However, little is known regarding the social support needs of older adults with cancer. The objective of the current study was to examine social support needs, specifically the unmet needs, among older adults with cancer. Read More

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December 2018

Correlates of nurses' motivation and their demographic characteristics.

Nurs Forum 2018 Dec 3. Epub 2018 Dec 3.

Hematopoietic Stem Cell Transplantation, Comprehensive Cancer Center, King Fahad Medical City (KFMC), Riyadh, Saudi Arabia.

Background: Motivation is a significant concern for workforce management in healthcare organizations as it is linked to many important factors, such as performance, staff retention, and satisfaction.

Aim: To assess motivation level, assess sources of motivation, and identify the difference in motivation level in relation to nurses' characteristics.

Setting: The study was carried out in one major tertiary hospital in Riyadh, Kingdom of Saudi Arabia. Read More

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December 2018

What is the appropriate communication style for family members confronting difficult surrogate decision-making in palliative care?: A randomized video vignette study in medical staff with working experiences of clinical oncology.

Jpn J Clin Oncol 2018 Dec 1. Epub 2018 Dec 1.

Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, Japan.

Background: The family members of terminally ill patients are often requested to make difficult surrogate decisions during palliative care. This study sought to clarify the appropriate communication style for physicians as perceived by family members confronting difficult surrogate decision-making.

Methods: This experimental psychological study used scripted videos. Read More

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December 2018

Co-operative groups in the development of chemotherapy for gastric cancer.

Jpn J Clin Oncol 2018 Dec 1. Epub 2018 Dec 1.

Department of Clinical Oncology, St. Marianna University School of Medicine, Kawasaki-shi, Kanagawa, Japan.

In the multimodality treatment strategy for gastric cancer, chemotherapy has an important role in conferring survival benefit. For the last three decades, great progress has been achieved in adjuvant and palliative chemotherapy. Powerful combination regimens using doublet or triplet cytotoxic agents have been developed and new molecular targeted drugs, including trastuzumab and ramucirumab, have been introduced in clinical practice. Read More

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December 2018

A Focus on Patient-Centered Care Required to Address the Trauma of Hospitalization.

Authors:
Cynthia J Brown

JAMA Intern Med 2018 Dec 3. Epub 2018 Dec 3.

Comprehensive Center for Healthy Aging, Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham, Birmingham.

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December 2018

Can a complex adaptive systems perspective support the resiliency of the heart failure patient - informal caregiver dyad?

Curr Opin Support Palliat Care 2018 Nov 30. Epub 2018 Nov 30.

Centre for Health Education Scholarship, Department of Family Practice, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

Purpose Of Review: A holistic palliative approach for heart failure care emphasizes supporting nonprofessional informal caregivers. Informal caregivers play a vital role caring for heart failure patients. However, caregiving negatively affects informal caregivers' well being, and in turn heart failure patients' health outcomes. Read More

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November 2018

The experience of parents with children with myelomeningocele who underwent prenatal surgery.

J Pediatr Rehabil Med 2018 Nov 18. Epub 2018 Nov 18.

Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.

Background: Prenatal surgery for myelomeningocele (MMC) has been demonstrated to have benefits over postnatal surgery. Nevertheless, prenatal surgery requires a significant emotional, physical, and financial commitment from the entire family.

Methods: Mixed methods study of parents' perceptions regarding provider communication, treatment choices, and the family impact of having a child with MMC. Read More

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November 2018

Consensus on molecular imaging and theranostics in prostate cancer.

Lancet Oncol 2018 Dec;19(12):e696-e708

Department of Nuclear Medicine, Radboud University Medical Centre, Nijmegen, Netherlands; Department of Nuclear Medicine, The Institute of Cancer Research and The Royal Marsden National Health Service Foundation Trust, London, UK.

Rapid developments in imaging and treatment with radiopharmaceuticals targeting prostate cancer pose issues for the development of guidelines for their appropriate use. To tackle this problem, international experts representing medical oncologists, urologists, radiation oncologists, radiologists, and nuclear medicine specialists convened at the European Association of Nuclear Medicine Focus 1 meeting to deliver a balanced perspective on available data and clinical experience of imaging in prostate cancer, which had been supported by a systematic review of the literature and a modified Delphi process. Relevant conclusions included the following: diphosphonate bone scanning and contrast-enhanced CT are mentioned but rarely recommended for most patients in clinical guidelines; MRI (whole-body or multiparametric) and prostate cancer-targeted PET are frequently suggested, but the specific contexts in which these methods affect practice are not established; sodium fluoride-18 for PET-CT bone scanning is not widely advocated, whereas gallium-68 or fluorine-18 prostate-specific membrane antigen gain acceptance; and, palliative treatment with bone targeting radiopharmaceuticals (rhenium-186, samarium-153, or strontium-89) have largely been replaced by radium-223 on the basis of the survival benefit that was reported in prospective trials, and by other systemic therapies with proven survival benefits. Read More

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December 2018
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[Surgical strategy of diagnosis and treatment for acute perforated gastric cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Nov;21(11):1218-1222

Department of Gastrointestinal Surgery, Guangdong Provincial Hospital of Chinese Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.

Acute perforated gastric cancer (GC) is defined as an acute perforation of primary GC. It is a rare surgical acute abdominal disease that is mainly caused by advanced GC. The onset of acute perforation of GC is related to the depth of invasion. Read More

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November 2018

[Role of oncologic radiotherapy in multidisciplinary team treatment of malignant acute abdomen].

Authors:
Yuhong Dai Hong Qiu

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Nov;21(11):1212-1217

Tongji Hospital Cancer Center, Tongji Medical College Affiliated, Huazhong University of Science and Technology,Wuhan 430030, China. Email:

Malignant acute abdomen is a emergency with abrupt onset, rapid progress and often a complex etiology, presenting difficulties for treatment and high mortality. Therefore, multidisciplinary team (MDT) treatment modality is required. Compared with single-discipline diagnosis and treatment modality, diagnosis made from MDT discussion is more accurate, where specialists can improve efficiency and quality of the treatment through better communication. Read More

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November 2018

Palliative care in universal health coverage: What about humanitarian emergency assistance?

Authors:
Martin Schneider

Int J Public Health 2018 Nov 30. Epub 2018 Nov 30.

Institute of Global Health, University of Geneva, Geneva, Switzerland.

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November 2018

Defining the cut-off point of clinically significant postoperative fatigue in three common fatigue scales.

Qual Life Res 2018 Nov 30. Epub 2018 Nov 30.

Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Purpose: Postoperative fatigue (POF) is an often underestimated problem after surgery. Studies on POF often report fatigue scores without relating this to the clinical relevance for the patients. The aim of this study was to define the cut-off point for clinically significant POF in three commonly applied fatigue scales; the Postoperative Fatigue Scale, Christensen's Fatigue Scale, and the Chalder Fatigue Questionnaire. Read More

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November 2018
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Limits to the appropriateness of intensive care : Policy statement of the German Interdisciplinary Association of Intensive Care and Emergency Medicine (DIVI).

Med Klin Intensivmed Notfmed 2018 Nov 30. Epub 2018 Nov 30.

Medical Clinic and Medical Intensive Care Medicine, St.-Antonius Hospital, Dechant-Decker-Str. 8, 52249, Eschweiler, Germany.

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November 2018

Percutaneous drainage and management of fluid collections associated with necrotic or cystic tumors in the abdomen and pelvis.

Abdom Radiol (NY) 2018 Nov 30. Epub 2018 Nov 30.

Department of Radiology, Louisiana State University Health, Shreveport, LA, USA.

Purpose: The purpose of the study was to evaluate the efficacy and safety of percutaneous drainage for palliation of symptoms and sepsis in patients with cystic or necrotic tumors in the abdomen and pelvis.

Materials And Methods: This is a single center retrospective study of 36 patients (18 men, mean age = 51.1 years) who underwent percutaneous drainage for management of cystic or necrotic tumors in the non-postoperative setting over an 11-year period. Read More

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November 2018

Palliative therapy in pancreatic cancer-interventional treatment with radiofrequency ablation/irreversible electroporation.

Transl Gastroenterol Hepatol 2018 26;3:80. Epub 2018 Oct 26.

General and Pancreatic Surgery Unit, Pancreas Institute, University of Verona, Policlinico GB Rossi, Piazzale L.A. Scuro, Verona, Italy.

Pancreatic cancer (PC) is a solid tumor with still a dismal prognosis. Diagnosis is usually late, when the disease is metastatic or locally advanced (LAPC). Only 20% of PC are amenable to surgery at the time of diagnosis and the vast majority of them, despite radically resected will unavoidably recur. Read More

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October 2018
1 Read

Recent advances in non-surgical management of cancer in the elderly.

F1000Res 2018 15;7. Epub 2018 Nov 15.

Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA.

This article summarizes the seminal publications from mid-2016 through 2017 in the area of medical care for older adults with cancer. Areas addressed include chemotherapy tolerance and efficacy in the aged, geriatric fitness assessments, and advancements in palliative and supportive care. The practice-changing finding from this past year's publications is that antipsychotics should not be used in the management of terminal delirium in older adults receiving palliative care. Read More

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November 2018

Discordance between Physician and the General Public Perceptions of Prognostic Disclosure to Children with Serious Illness: a Korean Nationwide Study.

J Korean Med Sci 2018 Dec 26;33(49):e327. Epub 2018 Nov 26.

Department of Biomedical Informatics, Seoul National University College of Medicine, Seoul, Korea.

Background: It is difficult to decide whether to inform the child of the incurable illness. We investigated attitudes of the general population and physicians toward prognosis disclosure to children and associated factors in Korea.

Methods: Physicians working in one of 13 university hospitals or the National Cancer Center and members of the general public responded to the questionnaire. Read More

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December 2018

Clinical utility of Rhenium-hydroxyethylidene-1,1-diphosphonate as a bone pain palliative in multiple malignancies.

World J Nucl Med 2018 Oct-Dec;17(4):228-235

Division of Radiopharmaceuticals, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.

Rhenium-hydroxyethylidene-1,1-diphosphonate (Re-HEDP) is a clinically established radiopharmaceutical for bone pain palliation of patients with metastatic bone cancer. Herein, the effectiveness of Re-HEDP for the palliation of painful bone metastases was investigated in an uncontrolled initial trial in 48 patients with different types of advanced cancers. A group of 48 patients with painful bone metastases of lung, prostate, breast, renal, and bladder cancer was treated with 2. Read More

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December 2018

F-fluorodeoxyglucose positron emission tomography/computed tomography in carcinoma of unknown primary: A subgroup-specific analysis based on clinical presentation.

World J Nucl Med 2018 Oct-Dec;17(4):219-222

Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe, Parel, Maharashtra, India.

The aim of this study was to explore the clinical efficacy of F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in tumor detection in patients with proven or suspected carcinoma of unknown primary origin (CUP) and making a subgroup-specific analysis. This was a retrospective, cross-sectional survey of patients with CUP syndrome who were referred for F-FDG PET-CT studies over a 2-year period. FDG-PET-CT scans were performed in compliance with the standard whole-body protocol, i. Read More

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December 2018
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Opioid-Related Harms: Simplistic Solutions to the Crisis Ineffective and Cause Collateral Damage.

Health Serv Insights 2018 25;11:1178632918813321. Epub 2018 Nov 25.

St. Paul's Hospital, Hospice Palliative Care Program, Providence Health Care, Vancouver, BC, Canada.

The narrative of the opioid crisis is that ill-informed and careless prescribing by physicians has led to increases in opioid-related harms including overdose deaths. Focusing on reducing the access to prescribed opioids without treating substance use disorder has led to increases in use of heroin and illicitly produced fentanyl. Overall prescribing of opioids has declined causing collateral damage to those who use opioids appropriately to reduce pain and improve function. Read More

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November 2018
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Mobile health technology and home hospice care: promise and pitfalls.

Prog Palliat Care 2018 26;26(3):137-141. Epub 2018 Apr 26.

Department of Medicine, Division of Geriatrics and Palliative Medicine, Weill Cornell Medicine, New York, NY, USA.

With the increasing use of mobile devices (e.g., smart phones, tablets) in our everyday lives, people have the ability to communicate and share information faster than ever before. Read More

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April 2018
1 Read

Outcomes After Radiotherapy Alone for Metastatic Spinal Cord Compression in Patients with Oligo-metastatic Breast Cancer.

Anticancer Res 2018 Dec;38(12):6897-6903

Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, U.S.A.

Background/aim: Patients with oligo-metastatic breast cancer are a unique patient subgroup with more favourable outlook than most patients with metastatic disease. Prognostic factors in these patients with metastatic spinal cord compression (MSCC) were evaluated.

Patients And Methods: In 159 patients irradiated for MSCC from oligo-metastatic breast cancer, seven characteristics were retrospectively analyzed including age, interval between breast cancer diagnosis and irradiation of MSCC, time developing motor deficits, ambulatory status, involved vertebrae, performance score (ECOG-PS) and radiotherapy regimen. Read More

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December 2018
3 Reads

A Matched-Pair Study Comparing Surgery Plus Neoadjuvant Radio-Chemotherapy and Surgery Alone for High Rectal Cancers.

Anticancer Res 2018 Dec;38(12):6877-6880

Department of Surgery, Zealand University Hospital, Køge, Denmark.

Background/aim: The value of neoadjuvant radiochemotherapy for high rectal cancers is controversial. This study compared surgery plus neoadjuvant radiochemotherapy to surgery alone.

Patients And Methods: Fifty-two patients with stage II/III high rectal cancers treated with surgery plus neoadjuvant radiochemotherapy were matched (1:4) to 208 patients treated with surgery alone. Read More

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December 2018

Palliative Radiotherapy as a Treatment for Carcinoma Invasion of the Sacrum: An Observational Case Series Study.

Anticancer Res 2018 Dec;38(12):6797-6800

Departments of Radiology, Neurology and Surgery, Louisiana State University Health Sciences Center, Shreveport, LA, U.S.A.

Background/aim: Radiotherapy for carcinoma invasion of the sacrum (CIS) is an alternative treatment to surgery in patients with advanced, inoperable tumors or those not medically eligible for resection of the neoplasm. Herein we present an observational study of patients with imaging-confirmed CIS who were treated non-operatively with radiation.

Patients And Methods: A retrospective chart review of CIS patients treated with palliative radiotherapy (PR) during a 9-year period (2004-2013) was performed. Read More

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December 2018

[Progressive myoclonic epilepsy secondary to Lafora's body disease].

Medicina (B Aires) 2018 ;78(6):436-439

Sección Epilepsia, Servicio de Neurología, Hospital Italiano Buenos Aires, Argentina. E-mail:

Lafora's disease is infrequent. However, it is one of the most common causes of progressive myoclonus epilepsy. We present the case of a 19-year-old woman, without comorbidities and normal development that started at 8 years with seizures and that from 15 years, had progressive cognitive deterioration. Read More

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January 2018

Information provision as evaluated by people with cancer and bereaved relatives: A cross-sectional survey of 34 specialist palliative care teams.

Patient Educ Couns 2018 Nov 19. Epub 2018 Nov 19.

End-of-Life Care Research Group, Vrije Universiteit Brussel (VUB) & Ghent University, Brussels, Belgium. Electronic address:

Objective: To explore how individuals with cancer and bereaved relatives evaluate information provision by specialist palliative care services (PCSs).

Methods: A cross-sectional survey was conducted within four multidisciplinary palliative homecare teams (HCTs), 17 hospital-based palliative care units (PCUs) and 13 hospital-based mobile palliative support teams (PSTs) in Belgium. During four measurement periods, structured questionnaires were administered to people being guided by PCSs and relatives of patients who had died while under the care of PCSs. Read More

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November 2018

Addressing the Clinical Need for Novel Nonopioid Pain Relief Therapies for Cancer Patients.

J Vasc Interv Radiol 2018 Dec;29(12):1645

Department of Radiation Oncology, University of Virginia, 1215 Lee St., Charlottesville, VA 22908. Electronic address:

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December 2018

Predictors of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci co-colonization among nursing facility patients.

Am J Infect Control 2018 Nov 27. Epub 2018 Nov 27.

Department of Internal Medicine, Division of Geriatric and Palliative Medicine, University of Michigan Medical School, Ann Arbor, MI; Geriatrics Research Education and Clinical Center, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI.

Background: The emergence of vancomycin-resistant Staphylococcus aureus (VRSA) poses significant challenges for antibiotic therapy. We characterized the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) co-colonization that may facilitate resistance transfer and vancomycin-resistant S aureus emergence among nursing facility patients.

Methods: We cultured newly admitted patient hands, nares, oropharynx, groin, and perianal region plus wounds and device insertion sites, if applicable, upon enrollment at day 14, day 30, and monthly follow-up up to 6 months. Read More

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November 2018

Validation of a concise screening tool for the identification of palliative care needs among inpatients: A prospective study in hospital setting.

J Formos Med Assoc 2018 Nov 27. Epub 2018 Nov 27.

Taipei City Hospital, Taipei, Taiwan; College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address:

Background/purpose: Very few studies have investigated the screening tools that aim to identify the need of palliative care services among patients with advanced cancer or chronic non-malignant diseases. This study validated the one-page Taiwanese version-Palliative Care Screening Tool (TW-PCST) for screening inpatients with potential palliative care needs.

Method: ROC curves were produced to examine the sensitivities and specificities at varying cut-off points. Read More

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November 2018
1 Read

Lessons learnt from establishing a high dose opioid review clinic for people living with HIV.

Pain Manag 2018 Dec 3. Epub 2018 Dec 3.

Consultant in Palliative Medicine, Department of Palliative Care, Chelsea & Westminster Hospital NHS Foundation Trust, London, UK.

People living with HIV represent a unique aging population, living with a chronic condition associated with significant pain. A number take high dose, long-term opioids to manage moderate to severe chronic pain, presenting specific risks. This article highlights the size and impact of this problem and outlines the service objectives and set up of a specialist clinic to manage people living with HIV on high dose opioids, alongside its successes and learning points. Read More

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December 2018

Peripherally inserted central catheter, midline, and "short" midline in palliative care: Patient-reported outcome measures to assess impact on quality of care.

J Vasc Access 2018 Dec 3:1129729818814732. Epub 2018 Dec 3.

1 Antea Palliative Care Centre, Rome, Italy.

Objectives:: A prospective, observational study was conducted in our palliative care unit to assess the impact of peripherally inserted central catheters (PICCs), midline, and "short" midline catheters on the quality of care in cancer and non-cancer patients. The secondary objective was to assess pain and distress during vascular access device insertion.

Methods:: Patients were recruited if they underwent insertion of a PICC, midline, or "short" midline catheter as part of their standard care. Read More

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December 2018

Early initiation of palliative care is associated with reduced late-life acute-hospital use: A population-based retrospective cohort study.

Palliat Med 2018 Dec 3:269216318815794. Epub 2018 Dec 3.

3 Institute for Clinical Evaluative Sciences, McMaster University Medical Centre, Hamilton, ON, Canada.

Background:: Early palliative care can reduce end-of-life acute-care use, but findings are mainly limited to cancer populations receiving hospital interventions. Few studies describe how early versus late palliative care affects end-of-life service utilization.

Aim:: To investigate the association between early versus late palliative care (hospital/community-based) and acute-care use and other publicly funded services in the 2 weeks before death. Read More

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December 2018