90,429 results match your criteria Palliative & Supportive Care [Journal]


Palliative care in end-stage heart failure: experience of a collaborative approach in a secondary care setting.

Intern Med J 2019 Mar;49(3):404-407

Te Omanga Hospice, Lower Hutt, New Zealand.

Heart failure remains an ultimately fatal condition that causes significant symptoms as it progresses. The involvement by palliative services in this patient group has been suboptimal despite many years of guidance from international cardiac societies who recommend a palliative focus for these patients. At Hutt hospital, we have implemented a cardiology supportive care clinic in an attempt to improve the care of our advanced heart failure patients. Read More

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http://dx.doi.org/10.1111/imj.14218DOI Listing

Elevated FPR confers to radiochemoresistance and predicts clinical efficacy and outcome of metastatic colorectal cancer patients.

Aging (Albany NY) 2019 Mar 21. Epub 2019 Mar 21.

Department of Clinical Laboratory, Jiangxi Province Key Laboratory of Laboratory Medicine, The Second Affiliated Hospital of Nanchang University, Nanchan, Jiangxi 330006, China.

Association of chronic inflammation, primary tumor sidedness, adjuvant therapy and survival of metastatic colorectal cancer (mCRC) remains unclear. Circulating inflammatory cell, fibrinogen (Fib), albumin (Alb), pre-albumin (pAlb), Alb/Fib (AFR) and Fib/pAlb (FPR) were detected, and clinical outcome was obtained to determine the predictive, prognostic and monitoring roles of them in discovery and validation cohort. We found that elevated FPR, low AFR and poor survival was observed in right-sided mCRC comparing to the left-sided disease, elevated FPR harbored the highest areas under curve to independently predict poor progression-free survival and overall survival in overall and left-sided mCRC case in two cohorts. Read More

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http://dx.doi.org/10.18632/aging.101864DOI Listing

Reduction in MnSOD promotes the migration and invasion of squamous carcinoma cells.

Int J Oncol 2019 Mar 14. Epub 2019 Mar 14.

Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan, R.O.C.

Reactive oxygen species (ROS) homeostasis is maintained at a higher level in cancer cells, which promotes tumorigenesis. Oxidative stress induced by anticancer drugs may further increase ROS to promote apoptosis, but can also enhance the metastasis of cancer cells. The effects of ROS homeostasis on cancer cells remain to be fully elucidated. Read More

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http://dx.doi.org/10.3892/ijo.2019.4750DOI Listing

Implications of the Parenteral Opioid Shortage for Prescription Patterns and Pain Control Among Hospitalized Patients With Cancer Referred to Palliative Care.

JAMA Oncol 2019 Mar 21. Epub 2019 Mar 21.

Department of Palliative, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston.

Importance: The recent parenteral opioid shortage (POS) has potential implications for cancer-related pain management in hospitalized patients.

Objective: This study compared changes in opioid prescriptions and clinically improved pain (CIP) among patients treated by an inpatient palliative care (PC) team before and after our institution first reported the POS.

Design, Setting, And Participants: A cohort study of 386 eligible patients with cancer treated at a comprehensive cancer center 1 month before and after the announcement of the POS. Read More

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http://dx.doi.org/10.1001/jamaoncol.2019.0062DOI Listing

Experiences With Video Consultations in Specialized Palliative Home-Care: Qualitative Study of Patient and Relative Perspectives.

J Med Internet Res 2019 Mar 21;21(3):e10208. Epub 2019 Mar 21.

REHPA - Danish Knowledge Centre for Rehabilitation and Palliative Care, University of Southern Denmark, Nyborg, Denmark.

Background: The work of specialized palliative care (SPC) teams is often challenged by substantial amounts of time spent driving to and from patients' homes and long distances between the patients and the hospitals.

Objective: Video consultations may be a solution for real-time SPC at home. The aim of this study was to explore the use of video consultations, experienced by patients and their relatives, as part of SPC at home. Read More

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http://dx.doi.org/10.2196/10208DOI Listing

Red Blood Cell Transfusion in Palliative Care: A Survey of Palliative Care Physicians.

J Palliat Med 2019 Mar 21. Epub 2019 Mar 21.

1 Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.

Background: Red blood cell transfusion is one therapeutic option for the treatment of anemia. Current transfusion practices and factors influencing the decision to prescribe this therapy are not well understood.

Objective: To explore current transfusion practices, attitudes, and factors that influence the decision to transfuse among palliative care physicians. Read More

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http://dx.doi.org/10.1089/jpm.2018.0605DOI Listing

Educating Our Future Colleagues: Creating an MSW Palliative Care Practicum.

J Soc Work End Life Palliat Care 2019 Mar 21:1-9. Epub 2019 Mar 21.

b School of Social Work , University of Texas at Austin , Austin , TX , USA.

As the number of older adults and those with chronic medical conditions continues to rise, the need to train social work students in palliative and end-of-life competencies becomes critical. To address this growing need, the social work team at a large urban academic medical center in the Midwest developed an MSW concentration practicum in palliative and end-of-life care. During the practicum, students receive immersive training in palliative care social work values and the skills required for these specialized assessments, interventions, and evaluations. Read More

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http://dx.doi.org/10.1080/15524256.2019.1586806DOI Listing

The Role of Spiritual Care with the Introduction of an End of Life Order Set.

J Pastoral Care Counsel 2019 Mar;73(1):41-48

Sunnybrook Health Science Centre, Canada.

Delivering comprehensive end-of-life care to dying patients must involve addressing physical symptoms and psychosocial concerns. Care pathways have been introduced to support health care teams in delivering this care. This retrospective chart review explores the contributions of the Spiritual Care Team in the care of dying patients. Read More

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http://dx.doi.org/10.1177/1542305018822283DOI Listing

Economic burden of chemotherapy-treated recurrent and/or metastatic squamous cell carcinoma of the head and neck in france: real world data from the permanent sample of national health insurance beneficiairies.

J Med Econ 2019 Mar 21. Epub 2019 Mar 21.

e Gustave Roussy, Université Paris-Saclay, Service de Biostatistique et d'Epidémiologie , Villejuif , France / INSERM U1018, CESP, Université Paris-Sud, Université Paris-Saclay , Villejuif , France.

Aims: Overall survival (OS) of patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) is extremely poor. New therapeutic options emerge but need to establish their economic value. The objective was to describe the direct and related costs of R/M SCCHN in France. Read More

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http://dx.doi.org/10.1080/13696998.2019.1594837DOI Listing

Breast health awareness in an Arabic culture: A qualitative exploration.

J Adv Nurs 2019 Mar 20. Epub 2019 Mar 20.

Cancer and Palliative Care Nursing and Senior Investigator with All Ireland Institute of Hospice and Palliative Care. School of Nursing and Midwifery, Queen's University Belfast, Room 06.312, Medical Biology Centre, Block 97 Health Sciences 97 Lisburn Road, BT9 7BL.

Aim: To explore breast health awareness and the early diagnosis and detection methods of breast cancer from the perspective of women and primary healthcare providers in Saudi Arabia.

Background: A high incidence of advanced breast cancer exists in Saudi Arabia, particularly among younger women. This is due to poor awareness of breast cancer and its management, social customs and poor breast health awareness among healthcare providers. Read More

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http://dx.doi.org/10.1111/jan.14003DOI Listing

Surgical Management of Deep-Seated Metastatic Brain Tumors Using Minimally Invasive Approaches.

J Neurol Surg A Cent Eur Neurosurg 2019 Mar 20. Epub 2019 Mar 20.

Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, United States.

Background And Study Aims/objective:  Metastatic brain tumors are the most common type of adult brain tumors. Treatment involves surgery and/or radiation therapy. Surgery is typically reserved for patients with good neurologic function, solitary and accessible lesions, symptomatic lesions, and/or those with good systemic control of their primary cancer. Read More

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http://dx.doi.org/10.1055/s-0038-1676575DOI Listing

Human Development Index and its association with staff spiritual care provision: a Middle Eastern oncology study.

Support Care Cancer 2019 Mar 20. Epub 2019 Mar 20.

Middle East Cancer Consortium and Technion-Israel Institute of Technology, Haifa, Israel.

Background: Although staff spiritual care provision plays a key role in patient-centered care, there is insufficient information on international variance in attitudes toward spiritual care and its actual provision.

Methods: A cross-sectional survey of the attitudes of Middle Eastern oncology physicians and nurses toward eight examples of staff provision of spiritual care: two questionnaire items concerned prayer, while six items related to applied information gathering, such as spiritual history taking, referrals, and encouraging patients in their spirituality. In addition, respondents reported on spiritual care provision for their last three advanced cancer patients. Read More

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http://dx.doi.org/10.1007/s00520-019-04733-0DOI Listing

Predicting Response to Cancer Immunotherapy using Non-invasive Radiomic Biomarkers.

Ann Oncol 2019 Mar 21. Epub 2019 Mar 21.

Department of Radiology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

Introduction: Immunotherapy is regarded one of the major breakthroughs in cancer treatment. Despite its success, only a subset of patients responds - urging the quest for predictive biomarkers. We hypothesize that Artificial Intelligence (AI) algorithms can automatically quantify radiographic characteristics that are related to and may therefore act as non-invasive radiomic biomarkers for immunotherapy response. Read More

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http://dx.doi.org/10.1093/annonc/mdz108DOI Listing

Palliative Care for Stroke Patients and Their Families: Barriers for Implementation.

Front Neurol 2019 6;10:164. Epub 2019 Mar 6.

Department of Palliative Care, University Hospital Erlangen-Nuremberg, Erlangen, Germany.

Stroke is a leading cause of death, disability and is a symptom burden worldwide. It impacts patients and their families in various ways, including physical, emotional, social, and spiritual aspects. As stroke is potentially lethal and causes severe symptom burden, a palliative care (PC) approach is indicated in accordance with the definition of PC published by the WHO in 2002. Read More

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http://dx.doi.org/10.3389/fneur.2019.00164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414790PMC

Calcium electroporation and electrochemotherapy for cancer treatment: Importance of cell membrane composition investigated by lipidomics, calorimetry and in vitro efficacy.

Sci Rep 2019 Mar 18;9(1):4758. Epub 2019 Mar 18.

Center for Experimental Drug and Gene Electrotransfer, Department of Oncology, Copenhagen University Hospital Herlev, Herlev, Denmark.

Calcium electroporation is a novel anti-cancer treatment investigated in clinical trials. We explored cell sensitivity to calcium electroporation and electroporation with bleomycin, using viability assays at different time and temperature points, as well as heat calorimetry, lipidomics, and flow cytometry. Three cell lines: HT29 (colon cancer), MDA-MB231 (breast cancer), and HDF-n (normal fibroblasts) were investigated for; (a) cell survival dependent on time of addition of drug relative to electroporation (1. Read More

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http://dx.doi.org/10.1038/s41598-019-41188-zDOI Listing

Outbreak of Murine Infection with Associated with the Administration of a Pre- and Perinatal Methyl Donor Diet.

mSphere 2019 Mar 20;4(2). Epub 2019 Mar 20.

Division of Geriatric and Palliative Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA

Between October 2016 and June 2017, a C57BL/6J mouse colony that was undergoing a pre- and perinatal methyl donor supplementation diet intervention to study the impact of parental nutrition on offspring susceptibility to disease was found to suffer from an epizootic of unexpected deaths. Necropsy revealed the presence of severe colitis, and further investigation linked these outbreak deaths to a strain of ribotype 027 that we term 16N203. infection (CDI) is associated with antibiotic use in humans. Read More

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http://dx.doi.org/10.1128/mSphereDirect.00138-19DOI Listing

Communication with children and adolescents about the diagnosis of their own life-threatening condition.

Lancet 2019 Mar 14;393(10176):1150-1163. Epub 2019 Mar 14.

School of Public Health, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; Institute of Health and Wellbeing, Glasgow, UK; University of Glasgow and Royal Hospital for Children, Glasgow, UK.

When a child is diagnosed with a life-threatening condition, one of the most challenging tasks facing health-care professionals is how to communicate this to the child, and to their parents or caregivers. Evidence-based guidelines are urgently needed for all health-care settings, from tertiary referral centres in high-income countries to resource limited environments in low-income and middle-income countries, where rates of child mortality are high. We place this Review in the context of children's developing understanding of illness and death. Read More

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http://dx.doi.org/10.1016/S0140-6736(18)33201-XDOI Listing

Ebola virus disease and palliative care in humanitarian crises.

Lancet 2019 Mar 14;393(10176):1100. Epub 2019 Mar 14.

School of Health Studies, Western University, London, ON, Canada.

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http://dx.doi.org/10.1016/S0140-6736(19)30295-8DOI Listing

Personalized Radiation Therapy in Cancer Pain Management.

Cancers (Basel) 2019 Mar 19;11(3). Epub 2019 Mar 19.

Department of Oncology, Medical University of Bialystok, 15-027 Białystok, Poland.

The majority of advanced cancer patients suffer from pain, which severely deteriorates their quality of life. Apart from analgesics, bisphosphonates, and invasive methods of analgesic treatment (e.g. Read More

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http://dx.doi.org/10.3390/cancers11030390DOI Listing

Integration of breast cancer prevention and early detection into cancer palliative care model.

PLoS One 2019 20;14(3):e0212806. Epub 2019 Mar 20.

Discipline of Nursing, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.

Background: Breast cancer is common among Ghanaian women. Late stage presentation has been credited to knowledge deficit and lack of breast cancer prevention and early detection services for women.

Objective: This study aimed to develop a model to facilitate the integration of breast cancer prevention and early detection into cancer palliative care. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212806PLOS

Undergraduate Nursing Students' Perception of End-of-Life Care Education Placement in the Nursing Curriculum.

J Hosp Palliat Nurs 2019 Mar 20. Epub 2019 Mar 20.

Jing Li, MSN, RN, is nursing lecturer, School of Pharmaceutical Engineering & Life Science, School of Nursing Changzhou University, China. Angel Smothers, DNP, APRN, FNP-BC, is certified faith community nurse, certified hospice and palliative care nurse, and clinical assistant professor, West Virginia University School of Nursing, Morgantown. Wei Fang, PhD, is statistical analyst, West Virginia University Health Sciences Center, Erma Byrd Biomedical Research Center, and West Virginia Clinical and Translational Science Institute, Morgantown, WV. Michelle Borland, DNP, RN, CNE, is assistant professor, West Virginia University School of Nursing, Morgantown.

Nursing students, who have been receiving the End-of-Life Nursing Education Consortium (ELNEC) Core training throughout their Bachelor of Science in Nursing program, have a unique perspective of the benefits of this training. In addition, they have insight as to where an online ELNEC module series specifically for undergraduate nursing students would best be integrated within the curriculum. This study used a mixed methods strategy to evaluate students' opinions on the placement of end-of-life care education within the curriculum and their experience of having received ELNEC training previously throughout their program. Read More

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http://dx.doi.org/10.1097/NJH.0000000000000533DOI Listing

Implementing the Serious Illness Care Program in Primary Care.

J Hosp Palliat Nurs 2019 Mar 20. Epub 2019 Mar 20.

Jill A. Massmann DNP, APRN, CNS, AGCNS-BC, OCN, ACHPN, is a palliative care clinical nurse specialist, St. Cloud Hospital; and was DNP student (during project implementation), Department of Nursing, Winona State University, Rochester. Minnesota. Sara S. Revier MSN, APRN, CNS, ACNS-BC, ACHPN, is a palliative care clinical nurse specialist, St. Cloud Hospital, Minnesota. Julie Ponto PhD, APRN, CNS, AGCNS-BC, AOCNS, is professor and AGCNS program coordinator, Department of Nursing, Winona State University, Rochester, Minnesota.

Inadequate communication about serious illness care preferences affects patients, families, health care providers, and health care systems. Many patient and system barriers prevent comprehensive serious illness communication. The purpose of this evidence-based practice project was to provide a structure within a primary care clinic to facilitate conversations with seriously ill individuals about their care preferences that (a) was adaptable to clinic workflow, (b) improved providers' perception of the care conversation experience, (c) improved documentation of care preferences, and (d) provided a comfortable and helpful experience. Read More

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http://dx.doi.org/10.1097/NJH.0000000000000531DOI Listing

Cytochrome P450 in Palliative Care and Hospice Kits.

Authors:
Mary Jo Quinn

J Hosp Palliat Nurs 2019 Mar 20. Epub 2019 Mar 20.

Mary Jo Quinn, MS, APRN, NP-C, ACHPN, is nurse practitioner, HouseCalls, Lakeland, Florida.

As hospice and palliative care populations shift from the majority having a primary cancer diagnosis to most with a noncancer diagnosis, clinicians are challenged with caring for chronically ill patients with multiple comorbidities. In addition to traditional pain and symptom management, patients' comfort goals are frequently addressed by managing the underlying disease and comorbid conditions. As a result, many patients have extensive medication profiles. Read More

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http://dx.doi.org/10.1097/NJH.0000000000000524DOI Listing

Improving Attitudes and Perceptions About End-of-Life Nursing on a Hospital-Based Palliative Care Unit.

J Hosp Palliat Nurs 2019 Mar 20. Epub 2019 Mar 20.

Kristine J. Harrington, DNP, RN, AGNP-C, is palliative care nurse practitioner, Providence Cancer Institute Franz Clinic, Providence Portland Medical Center; and adjunct professor, University of Portland School of Nursing, Oregon. Mary Lou Affronti, DNP, RN, MHSc, ANP, is associate professor, Duke University School of Nursing; primary investigator and nurse practitioner, Preston Robert Tisch Brain Tumor Center; and primary investigator and nurse practitioner, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina. Susan M. Schneider, PhD, RN, AOCN, FAAN, is associate professor, Duke University School of Nursing, Durham, North Carolina; and president, Oncology Nursing Society, Pittsburgh, Pennsylvania. Abdul Rab Razzak, MD, is director of outpatient palliative care, Johns Hopkins Medical Institutions, Baltimore, Maryland. Thomas J. Smith, MD, FACP, FASCO, FAAHPM, is director of palliative care, Johns Hopkins Medical Institutions, Baltimore, Maryland.

Nurses play an integral role in high-quality patient care. Thus, their skills in providing end-of-life care should be assessed and continually enhanced. Education intended to improve end-of-life skills must address the affective/emotional component of nursing care. Read More

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http://dx.doi.org/10.1097/NJH.0000000000000523DOI Listing

Experiences of symptoms and health service preferences among older people living with chronic diseases during the last year of life.

Int J Palliat Nurs 2019 Mar;25(3):129-141

Associate Professor, Director of the Thailand, Center for Evidence-Based Health Care: A collaborating Excellent Centre of Joanna Briggs Institute, Faculty of Nursing Chiang Mai University, Thailand.

Background:: There is limited understanding of the symptoms that older people living with cancer, chronic obstructive pulmonary disease and chronic kidney disease experience during the last year of life in Thailand, in addition to their health service preferences.

Aims:: To survey the symptom experiences and health service preferences at the end of life of older people with chronic illnesses from the perspective of bereaved carers.

Methods:: The study used a retrospective post-bereavement approach to collect quantitative data. Read More

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http://dx.doi.org/10.12968/ijpn.2019.25.3.129DOI Listing

Advance care planning for patients and their relatives.

Int J Palliat Nurs 2019 Mar;25(3):112-127

Centre for Health Sciences Education, Aarhus University, Denmark.

Background:: Advance care planning (ACP) has been suggested to improve the quality of life (QoL) and mental wellbeing in severely ill patients and their relatives.

Aim:: To investigate the effects of ACP among patients with lung, heart and cancer diseases with an estimated life-span of up to 12 months.

Methods:: Patients and relatives were randomised into two groups: one receiving usual care and one receiving ACP and usual care. Read More

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http://www.magonlinelibrary.com/doi/10.12968/ijpn.2019.25.3.
Publisher Site
http://dx.doi.org/10.12968/ijpn.2019.25.3.112DOI Listing
March 2019
1 Read

Politics and palliative care: Eswatini.

Authors:
Dion Smyth

Int J Palliat Nurs 2019 Mar;25(3):154

Lecturer-practitioner in Cancer and Palliative Care, Birmingham City University, Birmingham, UK.

Dion Smyth's review of palliative nursing on the internet. Read More

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http://dx.doi.org/10.12968/ijpn.2019.25.3.154DOI Listing

The nurse-led model of hospice care.

Int J Palliat Nurs 2019 Mar;25(3):143-149

Professor, Foundation of Nursing Studies, Professor of Practice Learning, School of Healthcare Sciences, Bangor University, North Wales.

Background:: Palliative care in the UK has become more medicalised over the last 50 years, and it was recognised as a medical speciality in 2004. However, out of financial expediency, an inpatient hospice in North Wales has become nurse-led.

Aims:: This article considers the history of care of the dying and discusses how nurses are best placed to be masters of care of the dying. Read More

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http://dx.doi.org/10.12968/ijpn.2019.25.3.143DOI Listing

Research Roundup.

Authors:
Karen Heggs

Int J Palliat Nurs 2019 Mar;25(3):151-153

Lecturer in Adult Nursing Division of Nursing, Midwifery and Social Work, School of Health Sciences The University of Manchester.

Synopses of a selection of recently published research articles of relevance to palliative care. Read More

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http://dx.doi.org/10.12968/ijpn.2019.25.3.151DOI Listing

Exploring patients' interest in complementary therapies in a specialist palliative care unit.

Int J Palliat Nurs 2019 Mar;25(3):108-110

Consultant Physician in Palliative Medicine, Marymount University Hospital and Hospice, Curraheen, Co Cork, Ireland.

Background:: The use of complementary therapy has become increasingly integrated into specialist palliative care units (SPCUs).

Objective:: To evaluate patients' interest in and experience of complementary therapies during their inpatient stay in a SPCU.

Method:: All 179 patients admitted to the SPCU over a 3-month period were assessed on admission. Read More

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http://dx.doi.org/10.12968/ijpn.2019.25.3.108DOI Listing

Evidence for integration of palliative care into surgical oncology practice and education.

J Surg Oncol 2019 Mar 20. Epub 2019 Mar 20.

Department of Obstetrics & Gynecology, Division of Gynecologic Oncology, University of Colorado School of Medicine, Aurora, Colorado.

High-quality data support multiple clinical benefits of integrating palliative care into routine oncology care. Though these data come largely from the medical oncology literature, data from surgical oncology populations support similar associations between palliative care integration and improved clinical outcomes, all without compromise in survival. This paper will review data supporting palliative care integration into oncology care, with a focus on surgical populations and recommendations for incorporating palliative care into surgical oncology. Read More

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http://dx.doi.org/10.1002/jso.25454DOI Listing

Palliative care in emergency medicine: A perennial skill with a new emphasis.

Authors:
Jennifer Hughes

CJEM 2019 Mar;21(2):163-164

*Cumming School of Medicine,University of Calgary,Calgary,AB.

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http://dx.doi.org/10.1017/cem.2019.7DOI Listing

Legacy Artwork in Pediatric Oncology: The Impact on Bereaved Caregivers' Psychological Functioning and Grief.

J Palliat Med 2019 Mar 20. Epub 2019 Mar 20.

5 Division of Pediatric Hematology and Oncology, University of Alabama at Birmingham, Birmingham, Alabama.

Background: Legacy-making (i.e., a way for patients with terminal illness to create or do something for others as a means of remembrance) is rising in popularity in palliative medicine, although only one study has examined its impact in a pediatric population. Read More

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http://dx.doi.org/10.1089/jpm.2018.0329DOI Listing

A Nationwide Study of Young Adults' Perspectives on Participation in Bereavement Research.

J Palliat Med 2019 Mar 20. Epub 2019 Mar 20.

3 Department of Health Care Sciences, Palliative Research Centre, Ersta Sköndal Bräcke University College, Stockholm, Sweden.

Background: Young adults represent a minority in research; they are often considered too young or too old for participation. There is sparse information, especially in bereavement research, regarding how this age group perceives research participation and what they consider beneficial or harmful.

Aim: To explore how parentally bereaved and nonbereaved young adults perceive research participation. Read More

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http://dx.doi.org/10.1089/jpm.2018.0630DOI Listing

Prospect Theory Concepts Applied to Family Members of Nursing Home Residents with Cancer: A Good Ending Is a Gain.

J Soc Work End Life Palliat Care 2019 Mar 20:1-21. Epub 2019 Mar 20.

d Program in Bioethics and Humanities, Carver College of Medicine , University of Iowa , Iowa City , Iowa , USA.

Family members are often involved in medical decision-making on behalf of a nursing home resident. Prospect theory provides a framework for understanding how people weigh decisions. In the current study, prospect theory concepts are used to build understanding about how family members weigh medical decisions for an NH resident diagnosed with cancer. Read More

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http://dx.doi.org/10.1080/15524256.2019.1580242DOI Listing
March 2019
2 Reads

Results of a nationwide hospice and palliative care social work job analysis.

J Soc Work End Life Palliat Care 2019 Mar 20:1-18. Epub 2019 Mar 20.

c PSI Services , Olathe , Kansas , United States.

The role of the hospice and palliative social worker is often ambiguous and misunderstood by colleagues and fellow team members. One reason for this is the lack of identified, clearly delineated roles, skills, and tasks employed by these specialty social workers in their daily work. This article summarizes the first nationwide job analysis of hospice and palliative social workers. Read More

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http://dx.doi.org/10.1080/15524256.2019.1577326DOI Listing

Management of Diabetes Mellitus in Adults at the End of Life: A Review of Recent Literature and Guidelines.

J Palliat Med 2019 Mar 20. Epub 2019 Mar 20.

2 Department of Palliative Care, Bruyère Continuing Care, Ottawa, Ontario, Canada.

Background: The prevalence of diabetes mellitus (DM) is rising with an increased risk of developing it as a person ages. Therefore, more persons will have comorbid DM throughout their health journey and are potentially prone to unpleasant symptoms associated with poor glycemic control at the end of life (EOL). We performed an in-depth literature review to examine evidence-based recommendations on DM management at the EOL. Read More

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http://dx.doi.org/10.1089/jpm.2018.0614DOI Listing
March 2019
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Attitudes of Liver and Palliative Care Clinicians toward Specialist Palliative Care Consultation for Patients with End-Stage Liver Disease.

J Palliat Med 2019 Mar 20. Epub 2019 Mar 20.

4 Section of Palliative Care, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin.

Objective: Delays in specialized palliative care (PC) consultation in end-stage liver disease (ESLD) patients may be explained by clinician attitudes toward PC. Our aim is to assess the attitudes of hepatology and liver transplant (HLT) and PC clinicians toward PC consultation and consultant roles in ESLD patient care.

Methods: Clinician members of HLT and PC professional societies were surveyed. Read More

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http://dx.doi.org/10.1089/jpm.2018.0553DOI Listing

Stenting the Upper/Cervical Oesophagus with a Proximal Deployment Cervical Oesophageal Stent: Technique and Outcomes.

Cardiovasc Intervent Radiol 2019 Mar 19. Epub 2019 Mar 19.

Department of Interventional Radiology, Maidstone and Tunbridge Wells NHS Trust, Maidstone Hospital, Hermitage Lane, Maidstone, Kent, ME16 9QQ, UK.

Introduction: Proximal oesophageal stent deployment continues to provide challenges due to the proximity of the upper oesophageal sphincter and the associated subsequent complications such as globus sensation and stent migration. Patients with cervical oesophageal cancer have previously had limited stenting options available to them with a paucity of the literature describing the radiological technique for successfully placing these high-risk stents. In this paper, we present our experience using the Taewoong Niti-S CERVICAL Oesophageal Stent. Read More

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http://dx.doi.org/10.1007/s00270-019-02201-0DOI Listing

Targeting Immune-Related Molecules in Cancer Therapy: A Comprehensive Analysis on Patient-Derived Tumor Models.

Biomed Res Int 2019 12;2019:4938285. Epub 2019 Feb 12.

Molecular Oncology and Immunotherapy, Department of General Surgery, Germany.

This study investigated the impact of immune-related pathway inhibition, among them indolamine 2,3-dioxygenase (IDO), alone and together with immune cells on growth and viability of colorectal cancer (CRC) cells. A panel of patient-derived CRC cell lines with different molecular characteristics (CpG island methylator phenotype, chromosomal, and microsatellite instability) was included. Initial phenotyping of CRC cell lines (n=17) revealed high abundance of immunosuppressive checkpoint-molecules in general, but an individual profile for IDO. Read More

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http://dx.doi.org/10.1155/2019/4938285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390245PMC
February 2019

pneumonia: An unusual presentation of nontuberculous mycobacterial infection requiring a novel multidisciplinary approach to management.

Respir Med Case Rep 2019 28;26:307-309. Epub 2019 Feb 28.

Department of Respiratory Medicine, Galway University Hospital, Ireland.

Background: is a rapidly growing nontuberculous mycobacterium which has been associated with several infections including cellulitis, osteomyelitis, lymphadenitis, infected pacemakers and bursitis but it is a rare cause of respiratory infection.

Case Presentation: In this case report we describe a 51-year-old woman who presented with a 6-week history of non-productive cough, pleuritic chest pain and weight loss. She had a history of gastric adenocarcinoma managed with a distal oesophagectomy and total gastrectomy and consequentially suffered severe post-operative gastric reflux. Read More

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http://dx.doi.org/10.1016/j.rmcr.2019.02.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404650PMC
February 2019

[Hospital admissions into paediatric palliative care: A retrospective study].

An Pediatr (Barc) 2019 Mar 16. Epub 2019 Mar 16.

Unidad de Cuidados Paliativos Pediátricos, Servicio de Pediatría, Hospital Infantil Universitario del Niño Jesús, Madrid, España.

Introduction: Patients may be admitted to hospital by paediatric palliative care units (PPCU) for different reasons, due to their different needs and clinical problems. The objective of this study is to present the data of patients admitted to the PPCU of the Autonomous Community of Madrid.

Methods: Descriptive retrospective study was conducted by reviewing the clinical records of the PPCU between January 2011 and December 2016. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S16954033193007
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http://dx.doi.org/10.1016/j.anpedi.2019.02.001DOI Listing
March 2019
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Adult Comorbidity Evaluation-27 as a predictor of postoperative complications, two-year mortality, duration of hospital stay, and readmission within 30 days in patients with squamous cell carcinoma of the head and neck.

Br J Oral Maxillofac Surg 2019 Mar 16. Epub 2019 Mar 16.

Oral and Maxillofacial Surgery, Leeds Teaching Hospitals Trust, United Kingdom. Electronic address:

The Adult Comorbidity Evaluation (ACE)-27 is a validated scoring system for comorbid conditions. We have evaluated the correlation between it and the duration of hospital stay, readmission within 30 days, complications, and two-year survival in patients having primary surgical treatment for squamous cell carcinoma (SCC) of the head and neck. We studied patients with SCC who had selective neck dissection, resection of the tumour, and reconstruction between 2007 and 2013. Read More

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http://dx.doi.org/10.1016/j.bjoms.2019.01.004DOI Listing

Ethical failings of CPSO policy and the health care consent act: case review.

BMC Med Ethics 2019 Mar 19;20(1):20. Epub 2019 Mar 19.

University of Ottawa, Ottawa, ON, Canada.

End-of-life disputes in Ontario are currently overwhelmingly assessed through the singular lens of patient autonomy. The current dispute resolution mechanism(s) does not adequately consider evidence-based medical guidelines, standards of care, the patient's best interests, expert opinion, or distributive justice. We discuss two cases adjudicated by the Consent and Capacity board of Ontario that demonstrate the over emphasis on patient autonomy. Read More

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http://dx.doi.org/10.1186/s12910-019-0357-yDOI Listing

Rumination in bereaved parents: Psychometric evaluation of the Swedish version of the Utrecht Grief Rumination Scale (UGRS).

PLoS One 2019 19;14(3):e0213152. Epub 2019 Mar 19.

Department of Clinical Psychology and Experimental Psychopathology, University of Groningen, Groningen, Netherlands.

Background: Bereaved parents may be at higher risk to develop persistent, severe and disabling grief, termed prolonged grief. Grief rumination, repetitive thinking about the causes and consequences of the loss, is a malleable cognitive process that maintains prolonged grief. Grief rumination can be measured with the Utrecht Grief Rumination Scale (UGRS). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213152PLOS

How Can Activity Monitors Be Used in Palliative Care Patients?

J Palliat Med 2019 Mar 19. Epub 2019 Mar 19.

3 Palliative and Supportive Services, College of Nursing and Health Sciences, Flinders University, Adelaide, Australia.

Background: Physical activity in palliative care patients is closely linked to independence, function, carer burden, prognosis, and quality of life. Changes in physical activity can also be related to service provision needs, including requirements for support and prognosis. However, the objective measurement of physical activity is challenging, with options, including self-report, invasive and intensive measures such as calorimetry, or newer options such as pedometers and accelerometers. Read More

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http://dx.doi.org/10.1089/jpm.2018.0414DOI Listing

Primary central nervous system lymphoma in patients with and without HIV infection: a multicenter study and comparison with U.S national data.

Cancer Causes Control 2019 Mar 19. Epub 2019 Mar 19.

Department of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.

Purpose: Primary central nervous system lymphoma (PCNSL) in patients living with HIV (PLWH) is a distinct entity; however, the management is adopted from patients without HIV. The study aims to examine the differences in presentation, treatment, and outcomes of PCNSL patients with or without HIV.

Methods: We retrospectively compared the characteristics of 144 patients with PCNSL with and without HIV, and analyzed factors associated with overall and progression-free survival. Read More

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http://dx.doi.org/10.1007/s10552-019-01144-8DOI Listing

Physical Inactivity in Pulmonary Sarcoidosis.

Lung 2019 Mar 19. Epub 2019 Mar 19.

Centre for Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, King's College London, London, UK.

Purpose: Reduced physical activity in many chronic diseases is consistently associated with increased morbidity. Little is known about physical activity in sarcoidosis. The aim of this study was to objectively assess physical activity in patients with pulmonary sarcoidosis and investigate its relationship with lung function, exercise capacity, symptom burden, and health status. Read More

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http://dx.doi.org/10.1007/s00408-019-00215-6DOI Listing

[Ketamine for pain management].

Schmerz 2019 Mar 19. Epub 2019 Mar 19.

Perioperative, Intensive Care and Pain Medicine, University of Helsinki, Helsinki, Finnland.

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http://dx.doi.org/10.1007/s00482-019-0364-4DOI Listing