774,453 results match your criteria Pain medicine Malden Mass.[Journal]


Revisit rates following pediatric coblation tonsillectomy.

Int J Pediatr Otorhinolaryngol 2019 Apr 16;122:130-132. Epub 2019 Apr 16.

Emergency Department, Affiliated Renhe Hospital of China Three Gorges University, Yichang, Hubei, China.

Objective: To explore the rate of emergency department (ED) revisits and hospital readmissions following coblation tonsillectomy in children with sleep-disordered breathing (SDB) and/or recurrent tonsillitis.

Methods: A total of 2045 children underwent coblation tonsillectomy were recruited in the retrospective study. The number of revisits or readmissions was recorded and the reasons were analyzed. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.04.013DOI Listing

Mechanical modeling of pimple growth.

J Mech Behav Biomed Mater 2019 Apr 16;95:191-195. Epub 2019 Apr 16.

Advanced Materials for Energy and Environment, Department of Earth and Environmental Engineering, Columbia University, New York, NY, 10027, USA; School of Chemical Engineering, Northwest University, Xi'an, 710069, PR China.

Pimple is one of the most common skin diseases for humans, whose growth cause pain yet the corresponding mechanical analysis is lacking. A finite element model is developed to quantify the deformation field with the expansion of follicle, and then the mechanical stimulus is related to the sensation of pain during the development of pimple. Parametric studies show the dependence of mechanical stimulus and pain level on the pimple-surrounded structures, follicle depth and mechanical properties of the epidermis. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.04.017DOI Listing

The case series of peritonitis due to perforated peptic ulcer: How does conservative management play role?

Int J Surg Case Rep 2019 Apr 5;58:74-76. Epub 2019 Apr 5.

Department of Surgery, Songkhla Hospital, Muang, Songkhla, 90100, Thailand. Electronic address:

Introduction: Surgical intervention is a conventional treatment for perforated peptic ulcer patients. This study aims to determine whether and how conservative non-operative management plays role in patients with pneumoperitoneum-peritonitis due to perforated peptic ulcers.

Methods: A 9-year retrospective study was conducted in patients, who visit one surgeon service, with peritonitis due to perforated peptic ulcer and received non-operation conservative treatment. Read More

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http://dx.doi.org/10.1016/j.ijscr.2019.03.054DOI Listing

Simultaneous small bowel and colon obstruction due to splenosis. A case report and review of literature.

Int J Surg Case Rep 2019 Mar 30;58:63-66. Epub 2019 Mar 30.

Department of General and Digestive Surgery, Maritime Hospital, Jbeil, Lebanon.

Introduction: Splenosis, an autotransplantation of splenic tissues in another compartment of the body, is only symptomatic when hematologic diseases have recurred or compression of other adjacent structures have occurred. Therefore, we report a clinical case of a patient with bowel obstruction due to splenosis.

Case Presentation: A patient with a history of splenectomy, presented to the emergency room for abdominal pain and obstipation, suggesting intestinal obstruction which is also seen on CT scan. Read More

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http://dx.doi.org/10.1016/j.ijscr.2019.03.040DOI Listing

Pretreatment with resveratrol ameliorate trigeminal neuralgia by suppressing matrix metalloproteinase-9/2 in trigeminal ganglion.

Int Immunopharmacol 2019 Apr 18;72:339-347. Epub 2019 Apr 18.

Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China; Department of Pediatric and Preventive Dentistry, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China. Electronic address:

Trigeminal neuralgia (TN) is a common type of neuropathic pain whereas the underlying pathogenesis has not been completely elucidated. Recent study suggests that the development of neuroinflammation is responsible for generating and sustaining neuropathic pain. The purpose of our study was to investigate the protective effect of intervening the inflammation in early stages of pain and explore its potential mechanism. Read More

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http://dx.doi.org/10.1016/j.intimp.2019.04.014DOI Listing

Inconsistency in Opioid Prescribing Practices After Pediatric Ambulatory Hernia Surgery.

J Surg Res 2019 Apr 19;241:57-62. Epub 2019 Apr 19.

Cohen Children's Medical Center, Northwell Health System, Division of Pediatric Surgery, New York, New York; Zucker School of Medicine at Hofstra/Northwell Health System, Department of Surgery, Manhasset, New York.

Introduction: Nonmedical opioid use is a major public health problem. There is little standardization in opioid-prescribing practices for pediatric ambulatory surgery, which can result in patients being prescribed large quantities of opioids. We have evaluated the variability in postoperative pain medication given to pediatric patients following routine ambulatory pediatric surgical procedures. Read More

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http://dx.doi.org/10.1016/j.jss.2019.03.043DOI Listing

Abdominal Pain in Children Develops With Age and Increases With Psychosocial Factors.

Clin Gastroenterol Hepatol 2019 Apr 19. Epub 2019 Apr 19.

Div of Pediatrics, Dept of Clinical and Experimental Medicine, Linköping university SE 58185 Linköping, Sweden; Crown Princess Victoria Children´s Hospital, Region Östergötland, Linköping, Sweden.

Background & Aims: Functional gastrointestinal disorders are highly prevalent, cause significant suffering, and are costly to society. Pain is a central feature of 2 of the most common functional gastrointestinal disorders-irritable bowel syndrome and functional dyspepsia. Although these disorders have been well studied in adults, their etiology is poorly understood. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15423565193042
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http://dx.doi.org/10.1016/j.cgh.2019.04.036DOI Listing
April 2019
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Spatial Patterns From High-Resolution Electrogastrography Correlate With Severity of Symptoms in Patients With Functional Dyspepsia and Gastroparesis.

Clin Gastroenterol Hepatol 2019 Apr 19. Epub 2019 Apr 19.

GI Innovation Group, University of California-San Diego, La Jolla, CA, USA; GI Motility & Physiology Program, University of California-San Diego, La Jolla, CA, USA. Electronic address:

Background & Aims: Invasive gastric electrical mapping has revealed spatial abnormalities of the slow wave in subjects with gastroparesis and functional gastrointestinal disorders. Cutaneous high-resolution electrogastrography (HR-EGG) is a non-invasive method that can detect spatial features of the gastric slow wave. We performed HR-EGG in subjects with active foregut symptoms to evaluate associations between gastric myoelectric abnormalities, symptoms (based on a validated questionnaire), and gastric emptying. Read More

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http://dx.doi.org/10.1016/j.cgh.2019.04.039DOI Listing

Extraforaminal L5 Nerve Root Compression Caused by Intervertebral Osteophyte Accompanied by Lumbosacral Transitional Vertebra: A Case Treated by Anterior Approach.

World Neurosurg 2019 Apr 19. Epub 2019 Apr 19.

Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

Background: Several authors have reported the occurrence of extraforaminal L5 nerve root compression between a LSTV and sacral ala, but reports on a lesion caused by an intervertebral osteophyte on the ventral and contralateral side of a unilateral abnormality by LSTV are hardly available CASE DESCRIPTION: A 67 -year -old woman presented with pain along the distribution of the L5 Nerve root, straight leg raise test, femoral nerve stretch test and Kemp test were positive on the left. Following plain radiographs, computerized tomography, magnetic resonance imaging and selective nerve root block, an osteophyte bridging the L5 and S1 vertebral bodies in the ventral side was identified compressing the L5 nerve root. On account of resistance to conservative therapy and the delicate position of the lesion, surgical treatment was performed by an anterior decompression the patient attained adequate relief from pain and could walk normally. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.04.104DOI Listing

Revisiting the middle cluneal nerves: an anatomical study with application to pain syndromes and invasive procedures around the sacrum.

World Neurosurg 2019 Apr 19. Epub 2019 Apr 19.

Seattle Science Foundation, Seattle, WA, USA; Department of Anatomical Sciences, St. George's University, St. George's, Grenada, West Indies.

Objective: The middle cluneal nerves (MCNs) are stated to arise from the sacral dorsal rami of S1 to S3 and supply the gluteal skin, but their detailed anatomy is unclear and often variably depicted and described. Therefore, the goal of this study was to revisit the anatomy of the MCNs and provide a clearer picture of their morphology.

Methods: Five fresh-frozen Caucasian cadavers (10 sides) (two males and three females) were dissected for this study. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.04.109DOI Listing

The Utility of MRI Results in Physician Decision Making Prior to Initial Lumbar Spinal Injection.

Spine J 2019 Apr 19. Epub 2019 Apr 19.

University of Colorado Department of Physical Medicine and Rehabilitation, 12631 E. 17th Avenue, Mail Stop F493, Academic Office 1 (AO1), Room 2510, Aurora, Colorado 80045, US.

Background Context: The need for advanced imaging prior to spinal intervention is an area of ongoing debate. Many studies have demonstrated the accuracy of MRI results in evaluating structural pathology in the lumbar spine, but few have addressed how frequently MRI findings change clinical management. A randomized controlled trial showed that viewing MRI results did not impact outcomes in patients with radiculopathy undergoing epidural steroid injection (ESI). Read More

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http://dx.doi.org/10.1016/j.spinee.2019.04.016DOI Listing

Influence of incidental dural tears and their primary microendoscopic repairs on surgical outcomes in patients undergoing microendoscopic lumbar surgery.

Spine J 2019 Apr 19. Epub 2019 Apr 19.

Department of Orthopaedic Surgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. Electronic address:

Background Context: Dural tear represents a common complication of microendoscopic spine surgery that may lead to postoperative sequelae including insufficient decompression, cerebrospinal fluid fistula, intracranial hypotension and subdural/intraparenchymal bleeding. The gold standard to manage intraoperative dural tears is primary repair. However, the downside of conversion to open surgery can be detrimental. Read More

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http://dx.doi.org/10.1016/j.spinee.2019.04.015DOI Listing

Oxytocin Effects on Pain Perception and Pain Anticipation.

J Pain 2019 Apr 19. Epub 2019 Apr 19.

Department of General Psychiatry, University Hospital of Heidelberg, 69115 Heidelberg.

There is an ongoing debate whether the neuropeptide oxytocin (OT) modulates pain processing in humans. This study differentiates behavioral and neuronal OT effects on pain perception and pain anticipation by using a Pavlovian conditioning paradigm. Forty-six males received intranasally administered OT in a randomized double-blind, placebo-controlled group design. Read More

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http://dx.doi.org/10.1016/j.jpain.2019.04.002DOI Listing

Inflammatory cytokines mediate the effects of diet and exercise on pain and function in knee osteoarthritis independent of BMI.

Osteoarthritis Cartilage 2019 Apr 19. Epub 2019 Apr 19.

Department of General Practice, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands; Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, USA; Department of Health and Exercise Science, Wake Forest University, Winston-Salem, USA; Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, USA; Department of Orthopedic Surgery, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands; Department of Health and Exercise Science, J. B. Snow Biomechanics Laboratory, Wake Forest University, Winston-Salem, USA.

Objective: Diet restriction and exercise form key treatments for osteoarthritis (OA) related symptoms in overweight and obese individuals. Although both interventions are known to influence systemic low-grade inflammation, which is related to pain levels and functional limitations, little is known about the potential changes in systemic inflammation as a working mechanism of diet restriction and exercise in knee OA.

Design: Data from the Arthritis, Diet, and Activity Promotion Trial (ADAPT) were used. Read More

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http://dx.doi.org/10.1016/j.joca.2019.04.009DOI Listing

Splenic Infarct After Warfarin Overdose Treatment; Is it coincidence or complication?

Authors:
Gökhan Yilmaz

Ann Vasc Surg 2019 Apr 19. Epub 2019 Apr 19.

Specialist, Emergency Medicine Clinic, Kayseri Training and Research Hospital, Kayseri, Turkey. Electronic address:

The Splenic infarct is a rare clinical condition seen in the emergency department and can mimic acute abdomen. Hematologic, vascular and thromboembolic events are considered in the etiology. Treatment options are varying between symptomatic treatment and splenectomy. Read More

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http://dx.doi.org/10.1016/j.avsg.2019.02.012DOI Listing

Laparoscopic Surgery in Chronic Mesenteric Ischaemia: Release of the Superior Mesenteric Artery from the Median Arcuate Ligament using the Transperitoneal Left Retrorenal Approach.

Ann Vasc Surg 2019 Apr 19. Epub 2019 Apr 19.

Department of Vascular and Thoracic Surgery, Hôpital Bichat, and SURVI (Structure d'URgences Vasculaires Intestinales), Intestinal Stroke Center, Groupe Hospitalier Universitaire Paris Nord Val de Seine (GHUPNVS), Faculté de Médecine Denis Diderot, Paris 7, France.

Median arcuate ligament (MAL) syndrome usually involves the celiac artery (CA) only. Far less frequently, both the CA and superior mesenteric artery (SMA) are compressed, leading to chronic mesenteric ischaemia. We report the case of a 46-year-old woman with a 4-year history of permanent nausea, postprandial abdominal pain and asthenia. Read More

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http://dx.doi.org/10.1016/j.avsg.2019.01.009DOI Listing

THE V -BLOCK OCCLUSION STENT AND SCLEROTHERAPY DEVICE FOR VARICOSE VEIN TREATMENT - A RETROSPECTIVE ANALYSIS.

Ann Vasc Surg 2019 Apr 19. Epub 2019 Apr 19.

Centre for Outpatient Vascular Treatment CAT.

Background: The procedure aims to show our results with a novel non-tumescent, non-thermal technique to treat varicose veins. The V Block occlusion stent is a minimally invasive device for treating reflux of the great saphenous vein. It is an office-based procedure that does not require tumescence anesthesia. Read More

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http://dx.doi.org/10.1016/j.avsg.2019.01.025DOI Listing

The effect of Xiang-Sha-Liu-Jun-Zi tang (XSLJZT) on irritable bowel syndrome: A randomized, double-blind, placebo-controlled trial.

J Ethnopharmacol 2019 Apr 19:111889. Epub 2019 Apr 19.

Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan; Chinese Medicine Research Center, China Medical University, Taichung 40402, Taiwan; Research Center for Chinese Medicine and Acupuncture, China Medical University, Taichung 40402, Taiwan; Department of Chinese Medicine, China Medical University Hospital, Taichung 40447, Taiwan. Electronic address:

Background: Irritable bowel syndrome (IBS) is characterized by chronic, recurrent abdominal pain or abdominal discomfort and changes in defecation habits. Xiang-Sha-Liu-Jun-Zi tang (XSLJZT) is a traditional Chinese medical formula that can modulate gastrointestinal disturbance.

Purpose: To investigate the therapeutic effect of XSLJZT on IBS. Read More

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http://dx.doi.org/10.1016/j.jep.2019.111889DOI Listing

Validation and interpretation of short form 12 and comparison with dermatology life quality index in atopic dermatitis in adults.

J Invest Dermatol 2019 Apr 19. Epub 2019 Apr 19.

Oregon Health & Science University, Portland, OR.

Quality of life (QOL) assessments are not standardized in atopic dermatitis (AD). We sought to determine the validity of Short-Form 12 (SF-12), a generic QOL assessment, in AD and compare its measurement properties with Dermatology Life Quality Index (DLQI). A cross-sectional, population-based study of 3495 adults was performed, including 602 that met a modified UK Working Party Criteria for AD. Read More

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http://dx.doi.org/10.1016/j.jid.2019.03.1152DOI Listing

Federal Bill Would Limit Opioid Scrips for Acute Pain.

Authors:
Joey Berlin

Tex Med 2018 Jun 1;114(6):42-44. Epub 2018 Jun 1.

The proposed three-day limit on opioid prescriptions for acute pain would be one of the more impactful provisions for pain doctors and their patients. Exceptions would include prescriptions for chronic pain, cancer care, hospice or end-of-life care, and pain treatment that's part of palliative care. Read More

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Attitudes and Perceptions Toward Authorized Deception: A Pilot Comparison of Healthy Controls and Fibromyalgia Patients.

Pain Med 2019 Apr 22. Epub 2019 Apr 22.

National Center for Complementary and Integrative Health.

Objective: Little is known about the perceptions and attitudes of participants who volunteer in studies involving authorized deception. Thus, this cross-sectional pilot study measured, for the first time, the perceptions about participation in an authorized-deception placebo analgesia study in chronic pain patients with fibromyalgia and assessed whether their perceptions differed from healthy controls.

Methods: An anonymous survey with questions about trust in research and willingness to participate in future research involving deception was mailed to participants in both groups after completion of the parent study. Read More

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http://dx.doi.org/10.1093/pm/pnz081DOI Listing

Gender-Stratified Prevalence of Psychiatric and Pain Diagnoses in a Primary Care Patient Sample with Fibromyalgia.

Pain Med 2019 Apr 22. Epub 2019 Apr 22.

Department of Family and Community Medicine, Saint Louis University School of Medicine, St. Louis, Missouri, USA.

Objective: Comorbid psychiatric and pain-related conditions are common in patients with fibromyalgia. Most studies in this area have used data from patients in specialty care and may not represent the characteristics of fibromyalgia in primary care patients. We sought to fill gaps in the literature by determining if the association between psychiatric diagnoses, conditions associated with chronic pain, and fibromyalgia differed by gender in a primary care patient population. Read More

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http://dx.doi.org/10.1093/pm/pnz084DOI Listing

Center of pressure progression patterns during level walking in adolescents with idiopathic scoliosis.

PLoS One 2019 22;14(4):e0212161. Epub 2019 Apr 22.

Department of Creative Product Design, Asia University, Taichung, Taiwan.

The purpose of this study was to determine whether functional walking performance measured with Timed Up-and-Go (TUG) and center of pressure (CoP) progression pattern is different across adolescents with various curve severity of idiopathic scoliosis (IS). The CoP coordinates during a stance phase for self-paced level walking between adolescent with three different severities of IS (mild IS, moderate IS, and severe IS) and age-matched normal subjects were measured with foot pressure measurement. The average data of three trials were compared among groups with repeated measure analysis of variance. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212161PLOS
April 2019
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Cost-effectiveness of acupuncture versus standard care for pelvic and low back pain in pregnancy: A randomized controlled trial.

PLoS One 2019 22;14(4):e0214195. Epub 2019 Apr 22.

AP-HP, Service de Gynécologie-Obstétrique- Hôpital Universitaire Pitié-Salpêtrière- Charles Foix, Paris, France.

Objective: To assess the cost-effectiveness of acupuncture for pelvic girdle and low back pain (PGLBP) during pregnancy.

Design: Pragmatic-open-label randomised controlled trial.

Setting: Five maternity hospitals. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214195PLOS

Trajectories of sickness absence and disability pension before and after opioid initiation for noncancer pain: a 10-year population-based study.

Pain 2019 May;160(5):1224-1233

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

Chronic noncancer pain is a leading cause of sickness absence (SA) and disability pension (DP). The objectives of this study were to identify trajectories of SA/DP before and after strong and weak opioid initiation for noncancer pain and the factors associated with these trajectories. A longitudinal population-based study of 201,641 people (24-59 years) without cancer who initiated opioid analgesics in 2009 in Sweden was conducted. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001500DOI Listing

Anterior nucleus of paraventricular thalamus mediates chronic mechanical hyperalgesia.

Pain 2019 May;160(5):1208-1223

Taiwan International Graduate Program in Molecular Medicine, National Yang-Ming University and Academia Sinica, Taipei, Taiwan.

Pain-related diseases are the top leading causes of life disability. Identifying brain regions involved in persistent neuronal changes will provide new insights for developing efficient chronic pain treatment. Here, we showed that anterior nucleus of paraventricular thalamus (PVA) plays an essential role in the development of mechanical hyperalgesia in neuropathic and inflammatory pain models in mice. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001497DOI Listing

Effectiveness and safety of 5% lidocaine-medicated plaster on localized neuropathic pain after knee surgery: a randomized, double-blind controlled trial.

Pain 2019 May;160(5):1186-1195

CHU Clermont-Ferrand, DRCI, Clermont-Ferrand, France.

Localized neuropathic pain symptoms are reported after knee surgery in 30% to 50% of patients. 5% lidocaine plaster (LP5) is recommended for localized neuropathic pain, but evidence in postsurgery neuropathic pain is missing. This study focuses on the effectiveness of LP5 on allodynia, hyperalgesia, and thermal stimuli in postsurgery knee localized neuropathic pain. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001502DOI Listing

Chronic pain is associated with a brain aging biomarker in community-dwelling older adults.

Pain 2019 May;160(5):1119-1130

Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Chronic pain is associated with brain atrophy with limited evidence on its impact in the older adult's brain. We aimed to determine the associations between chronic pain and a brain aging biomarker in persons aged 60 to 83 years old. Participants of the Neuromodulatory Examination of Pain and Mobility Across the Lifespan (NEPAL) study (N = 47) completed demographic, psychological, and pain assessments followed by a quantitative sensory testing battery and a T1-weighted magnetic resonance imaging. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001491DOI Listing

Towards a neurobiological understanding of pain in neurofibromatosis type 1: mechanisms and implications for treatment.

Pain 2019 May;160(5):1007-1018

Departments of Pharmacology and.

Neurofibromatosis type 1 (NF1) is the most common of a group of rare diseases known by the term, "Neurofibromatosis," affecting 1 in 3000 to 4000 people. NF1 patients present with, among other disease complications, café au lait patches, skin fold freckling, Lisch nodules, orthopedic complications, cutaneous neurofibromas, malignant peripheral nerve sheath tumors, cognitive impairment, and chronic pain. Although NF1 patients inevitably express pain as a debilitating symptom of the disease, not much is known about its manifestation in the NF1 disease, with most current information coming from sporadic case reports. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001486DOI Listing

Alexithymia in individuals with chronic pain and its relation to pain intensity, physical interference, depression, and anxiety: a systematic review and meta-analysis.

Pain 2019 May;160(5):994-1006

University of Washington, Seattle, WA, United States.

Numerous studies have examined how alexithymia (difficulty identifying and describing one's emotions and a preference for externally oriented thinking) relates to chronic pain and associated disability. We conducted a systematic review and meta-analysis to summarize individual studies that either assessed alexithymia in individuals with chronic pain vs controls or related alexithymia to pain intensity, physical interference, depression, and anxiety. We searched MEDLINE, Embase, and PsycINFO from inception through June 2017; 77 studies met the criteria (valid assessment of alexithymia in adults or children with any chronic pain condition) and were included in analyses (n = 8019 individuals with chronic pain). Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001487DOI Listing

Effects of low-level laser and low-intensity pulsed ultrasound therapy on treatment duration and pain perception.

J Clin Orthod 2019 Mar;53(3):154-162

Department of Orthodontics and Dentofacial Orthopedics, Government Dental Centre, New Delhi, India.

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Laparoscopic Percutaneous Extraperitoneal Internal Ring Closure for Pediatric Inguinal Hernia: 1,142 Cases.

J Laparoendosc Adv Surg Tech A 2019 Apr 20. Epub 2019 Apr 20.

Department of Pediatric Surgery, Fujian Provincial Maternity and Children's Hospital, Fuzhou, P.R. China.

The purpose of this study was to summarize the clinical experience of the laparoscopic percutaneous extraperitoneal closure of the internal ring using an epidural needle for the treatment of inguinal hernias. There were 1,142 children with an isolated inguinal hernia who participated in this study from January 2013 to May 2018. An epidural needle was used to treat the indirect inguinal hernia with laparoscopic assistance. Read More

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http://dx.doi.org/10.1089/lap.2018.0721DOI Listing

A Retrospective Database Review of the Indications, Complications, and Incidence of Subsequent Spine Surgery in 12,297 Spinal Cord Stimulator Patients.

Neuromodulation 2019 Apr 22. Epub 2019 Apr 22.

Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA, USA.

Study Design: Retrospective review.

Objective: To analyze the indications, incidence of minor and major complications, and rate of subsequent spinal surgery or revision after spinal cord stimulator (SCS) placement for degenerative spine disease.

Summary Of Background Data: Despite the application of SCS in various chronic pain conditions, there remains a growing debate on the efficacy and necessity of SCS in degenerative spine disease. Read More

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http://dx.doi.org/10.1111/ner.12952DOI Listing

Dental anxiety in schoolchildren with molar incisor hypomineralization - a population-based cross-sectional study.

Int J Paediatr Dent 2019 Apr 22. Epub 2019 Apr 22.

Department of Stomatology, Universidade Federal do Paraná, Curitiba, Brazil.

Background: Identifying patients with high levels of DA helps to define the most adequate oral healthcare strategy, especially for pediatric patients.

Aim: To investigate the association between parental reports of dental anxiety (DA) and molar incisor hypomineralization (MIH) in schoolchildren.

Design: A cross-sectional study was conducted in a representative sample of 731 eight-year-old schoolchildren from the city of Curitiba, Brazil, who were clinically examined (k ≥ 0. Read More

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http://dx.doi.org/10.1111/ipd.12503DOI Listing

N-Methyl-d-aspartate receptor open-channel blockers memantine and magnesium modulate nociceptive trigeminovascular neurotransmission in rats.

Eur J Neurosci 2019 Apr 22. Epub 2019 Apr 22.

Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.

Experimental and clinical studies suggest that the low-affinity N-methyl-d-aspartate (NMDA) receptor open-channel blockers Mg and memantine are effective in reducing trigeminal nociceptive activation. The aim of the present study was to investigate the apparent effectiveness of these channel blockers using a model of trigeminal activation in vivo. Rats were anesthetized before electrically stimulating the dura mater adjacent the middle meningeal artery. Read More

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http://dx.doi.org/10.1111/ejn.14423DOI Listing

Condylar repair and regeneration in adolescents/young adults with early-stage degenerative temporomandibular joint disease: a randomized controlled study.

J Oral Rehabil 2019 Apr 22. Epub 2019 Apr 22.

Center for TMD& Orofacial Pain, Peking University School & Hospital of Stomatology, Beijing, China.

Background: Anterior repositioning splint (ARS) can facilitate regenerative condylar remodeling.

Objective: To determine the effect of ARS on osseous condylar changes in adolescents/young adults with early-stage degenerative joint disease (DJD).

Methods: Sixty-nine patients with early-stage temporomandibular joint (TMJ) DJD based on the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) and cone-beam computed tomography (CBCT) imaging were recruited and randomly allocated to two treatment groups: (a) conservative therapy with ARS and (b) conservative therapy without ARS. Read More

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http://dx.doi.org/10.1111/joor.12805DOI Listing

A Retrospective Analysis of Selected Opioids in Hair of Workplace Drug Testing Subjects.

J Anal Toxicol 2019 Apr 22. Epub 2019 Apr 22.

Psychemedics Corporation, 5832 Uplander Way, Culver City, CA 90230, USA.

Opioids, both naturally occurring and semisynthetic, are effective pain management medications, but also possess the potential for abuse. Analyses of over 37,000 head and body hair samples containing codeine, morphine, hydrocodone, hydromorphone, oxycodone or oxymorphone provide a view of use habits of workplace-testing subjects that cannot be obtained from fluid matrices results. Testing was performed using FDA cleared immunoassays using either 2 ng morphine or oxycodone per 10 mg hair as calibrators. Read More

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http://dx.doi.org/10.1093/jat/bkz015DOI Listing
April 2019
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Effect of Albuterol Premedication vs Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies: The REACT Randomized Clinical Trial.

JAMA Pediatr 2019 Apr 22. Epub 2019 Apr 22.

Telethon Kids Institute, Perth, Australia.

Importance: Tonsillectomy is a common pediatric procedure for the treatment of sleep-disordered breathing and chronic tonsillitis. Up to half of children having this procedure experience a perioperative respiratory adverse event.

Objective: To determine whether inhaled albuterol sulfate (salbutamol sulfate) premedication decreases the risk of perioperative respiratory adverse events in children undergoing anesthesia for tonsillectomy. Read More

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http://dx.doi.org/10.1001/jamapediatrics.2019.0788DOI Listing

Anger Inhibition and Pain Modulation.

Ann Behav Med 2019 Apr 22. Epub 2019 Apr 22.

Department of Psychology, The University of Tulsa, Tulsa, OK, USA.

Background: The tendency to inhibit anger (anger-in) is associated with increased pain. This relationship may be explained by the negative affectivity hypothesis (anger-in increases negative affect that increases pain). Alternatively, it may be explained by the cognitive resource hypothesis (inhibiting anger limits attentional resources for pain modulation). Read More

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http://dx.doi.org/10.1093/abm/kaz016DOI Listing

Multi-Modal Signals for Analyzing Pain Responses to Thermal and Electrical Stimuli.

J Vis Exp 2019 Apr 5(146). Epub 2019 Apr 5.

Department of Medical Psychology, Ulm University.

The assessment of pain relies mostly on methods that require a person to communicate. However, for people with cognitive and verbal impairments, existing methods are not sufficient as they lack reliability and validity. To approach this problem, recent research focuses on an objective pain assessment facilitated by parameters of responses derived from physiology, and video and audio signals. Read More

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http://dx.doi.org/10.3791/59057DOI Listing

Anti-angiogenesis treatment in a patient with appendix metastasis of small cell lung cancer: A case report.

Medicine (Baltimore) 2019 Apr;98(16):e15333

Oncology Department, WangJing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Rationale: Small-cell lung cancer (SCLC) is a common pathological type of lung cancer, but appendiceal metastasis of SCLC was rare. At present, clinical studies on the maintenance therapy of SCLC have not reached a significant conclusion.

Patient Concerns: We reported on a 52-year-old man who diagnosed as extensive stage SCLC with abdominal pain for 2 months, aggravated for 2 days. Read More

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http://dx.doi.org/10.1097/MD.0000000000015333DOI Listing

Progressive sacroiliitis due to accessory sacroiliac joint mimicking ankylosing spondylitis: A case report.

Medicine (Baltimore) 2019 Apr;98(16):e15324

Department of Rheumatology, Kyung Hee University Hospital at Gangdong, School of Medicine, Kyung Hee University, Seoul, Korea.

Rationale: An accessory sacroiliac (SI) joint usually has little clinical significance. However, severe arthritic changes can cause chronic buttock or low back pain and can be misdiagnosed as another disease presenting with sacroiliitis such as ankylosing spondylitis (AS).

Patient Concerns: A 33-year-old woman was diagnosed with AS due to chronic buttock pain and progressive sacroiliitis on plain X-ray and magnetic resonance imaging (MRI). Read More

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http://dx.doi.org/10.1097/MD.0000000000015324DOI Listing

Subcutaneous tissue-sparing dorsal slit with new marking technique: A novel circumcision method.

Medicine (Baltimore) 2019 Apr;98(16):e15322

Department of Plastic Surgery.

Circumcision is a very common surgical procedure that is performed for medical and traditional purposes in the world. However, many technical of circumcision is needed to improve. Thus, this study introduced a novel method of circumcision that is a refined version of the sleeve technique, termed subcutaneous tissue sparing dorsal slit with new marking, and evaluated the safety and efficacy of this novel method of circumcision. Read More

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http://dx.doi.org/10.1097/MD.0000000000015322DOI Listing

Endovascular treatment of a ruptured thoracic aortic pseudoaneurysm secondary to Pott disease during a spine surgery: A case report and a literature review.

Medicine (Baltimore) 2019 Apr;98(16):e15306

Department of Orthopedic Surgery.

Rationale: The coexistence of a tuberculous aortic pseudoaneurysm and Pott disease in patients with a history of tuberculosis (TB) is relatively rare, and the treatment strategies remain still controversial.

Patient Concerns: A 57-year-old female patient with a history of primary pulmonary TB presented with symptoms of breathlessness, chest pain, weight loss, and fever. Magnetic resonance imaging (MRI) and computed tomography (CT) showed a thoracic aortic pseudoaneurysm secondary to Pott disease at T11/12 level. Read More

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http://dx.doi.org/10.1097/MD.0000000000015306DOI Listing

Platelet-rich plasma injection for the treatment of chronic Achilles tendinopathy: A meta-analysis.

Medicine (Baltimore) 2019 Apr;98(16):e15278

Department of Orthopedics, The Second Hospital of Tangshan, Tangshan City Hebei Province, PR China.

Background: Platelet-rich plasma (PRP) is used as an alternative therapy to reduce pain and improve functional restoration in patients with Achilles tendinopathy (AT). We evaluated the current evidence for the efficacy of PRP as a treatment for chronic AT.

Methods: The PubMed, Embase, Web of Science, and The Cochrane Library databases were searched for articles on randomized controlled trials (RCTs) that compared the efficacy of PRP with that of with placebo injections plus eccentric training as treatment for AT. Read More

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http://dx.doi.org/10.1097/MD.0000000000015278DOI Listing

Echinococcosis in left ventricle: a case report.

Medicine (Baltimore) 2019 Apr;98(16):e15267

Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.

Introduction: Echinococcosis, also called hydatid disease, is a common parasitic infection of the liver. However, echinococcus lesions rarely involve the heart, especially in children.

Patient Concerns: An 8-year-old child from grazing areas of northwest China was referred to our hospital for the complaint of inpersistent precordial chest pain and left upper quadrant pain for 3 years. Read More

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http://dx.doi.org/10.1097/MD.0000000000015267DOI Listing

Diagnostic challenges of spinal gout: A case series.

Medicine (Baltimore) 2019 Apr;98(16):e15265

Department of orthopedics, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.

Introduction: Spinal gout is rarely encountered in clinical practice, is easily misdiagnosed, and often remains undiagnosed. This paper aims to provide some clues that are the salient diagnostic features of spinal gout, particularly axial pain, radiculopathy, and myelopathy, as determined on the basis of our experience with a few cases as well as a literature review.

Methods: We retrospectively reviewed the clinical data of 5 patients that were treated for axial pain and neurological symptoms associated with spinal gout between 2014 and 2017 in our hospital. Read More

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http://dx.doi.org/10.1097/MD.0000000000015265DOI Listing

Spontaneous rotational dislocation of the lumbar spine in type 1 neurofibromatosis: A case report and literature review.

Medicine (Baltimore) 2019 Apr;98(16):e15258

Department of Spine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province, China.

Rationale: Scoliosis is the most common form of dystrophic spinal deformities in type 1 neurofibromatosis, whereas a spontaneous rotational dislocation of the lumbar spine is a rare entity. Former researchers had advocated the use of circumferential fusion performed through combined anterior-posterior approaches as the mode of treatment of this situation, but we managed to achieve a solid circumferential fusion equally using posterior approach alone.

Patient Concerns: A 51-year-old lady presented with severe back pain and no history of trauma, fever, or loss of weight. Read More

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http://dx.doi.org/10.1097/MD.0000000000015258DOI Listing

An occult urothelial carcinoma with wide multiorgan metastases and its genetic alteration profiling: Case report and literature review.

Medicine (Baltimore) 2019 Apr;98(16):e15245

Department of Comprehensive Internal Medicine, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning.

Rationale: Urothelial carcinoma, also named transitional cell carcinoma, is the most frequent occurring malignancy in the urinary system. It mainly invades the surrounding tissues and metastasizes to distant organs in later stages.

Patient Concerns: Here, we presented an unusual case of occult urothelial carcinoma primarily manifested as a multiorgan metastatic cancer in a 59-year-old man. Read More

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http://dx.doi.org/10.1097/MD.0000000000015245DOI Listing
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