758,195 results match your criteria Pain Physician[Journal]


[The multifaceted concept of mental disorder].

Authors:
Heinz Häfner

Fortschr Neurol Psychiatr 2018 Dec 17. Epub 2018 Dec 17.

Zentralinstitut für Seelische Gesundheit, AG Schizophrenieforschung; Medizinische Fakultät Mannheim / Universität Heidelberg.

The concept of mental disorder has many facets. Specific concepts of disease or disorder stand for individual entities, classified as diagnoses. Ideally, they are based on discrete physical, neurobiological or - as is the case with hereditary diseases - genetic findings. Read More

View Article
December 2018

Chemical characterization and source apportionment of PM personal exposure of two cohorts living in urban and suburban Beijing.

Environ Pollut 2018 Dec 4;246:225-236. Epub 2018 Dec 4.

College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China; CAS Center for Excellence in Regional Atmospheric Environment, Chinese Academy of Sciences, Xiamen, 361021, China. Electronic address:

In the study, personal PM exposures and their source contributions were characterized for 159 subjects living in the Beijing Metropolitan area. The exposures and sources were examined as functions of residential location, season, vocation, cigarette smoking, and time spent outdoors. Sampling was performed for two categories of volunteers, guards and students, that lived in urban and suburban areas of Beijing. Read More

View Article
December 2018

Association of quality of life with disease characteristics and treatment outcomes in patients with advanced gastric cancer: Exploratory analysis of RAINBOW and REGARD phase III trials.

Eur J Cancer 2018 Dec 14;107:115-123. Epub 2018 Dec 14.

Institute of Clinical Cancer Research (IKF), University Cancer Center, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. Electronic address:

Background: Inadequate understanding of interpretation of quality of life (QoL) instruments leads to unsatisfactory data reporting and clinical decision-making, including in gastric cancer care.

Materials And Methods: Pooled QoL data from two phase III studies of ramucirumab with or without paclitaxel in previously treated patients with gastric or gastroesophageal junction cancer were used to explore associations with clinical attributes, including tumour response, disease measurability and performance status (PS). The European Organisation for Research and Treatment of Cancer (EORTC) Quality-of-Life Questionnaire (QLQ)-C30 was used in both studies. Read More

View Article
December 2018

Contingent biofeedback outperforms other methods to enhance the accuracy of cardiac interoception: A comparison of short interventions.

J Behav Ther Exp Psychiatry 2018 Dec 4;63:12-20. Epub 2018 Dec 4.

Institute of Clinical Psychology and Psychotherapy, University of Cologne, Cologne, Germany. Electronic address:

Background And Objectives: Deviations in interoception might contribute to the development and maintenance of mental disorders. The improvement of interoceptive accuracy (IA) is desirable but assessment and training methods remain controversial. For instance, it was assumed that performance increases in heartbeat counting paradigms after cardiac feedback were due to an improvement of knowledge with regard to heart rate rather than due to an actual improvement in IA. Read More

View Article
December 2018

Synovial chondromatosis of the temporomandibular joint: report and analysis of 12 cases.

J Stomatol Oral Maxillofac Surg 2018 Dec 14. Epub 2018 Dec 14.

Service de stomatologie et chirurgie maxillo-faciale. AP-HP, DHU FAST, GH Pitie- Salpêtrière- Charles Foix, F-75013, Paris, France; Sorbonne Universités, UPMC Univ Paris 06, UMR 8256 B2A, F-75005, Paris, France.

OBJECTIVE - We had for aim to study the clinical manifestations, diagnostic imaging techniques, histopathological and therapeutic findings of patients presenting with synovial chondromatosis (CS) of the temporomandibular joint (TMJ). MATERIAL AND METHODS - We reviewed the clinical history of all our patients who were diagnosed with CS between 2009 and 2013. RESULTS - We identified 12 cases of TMJ-CS, in 4 male and 8 female patients, with a mean aged of 50. Read More

View Article
December 2018

Does the frequency of administration of long acting injectable antipsychotics impact psychiatric outcomes and adverse effects: A systematic review and meta-analysis.

J Psychiatr Res 2018 Dec 10;109:193-201. Epub 2018 Dec 10.

University of Queensland, School of Medicine, Brisbane, Australia; Metro South Addiction and Mental Health Service, Brisbane, Australia.

Dosing regimens for depot antipsychotics range from two-to twelve-weekly administration. There are limited meta-analytic data regarding the effect of different injection frequencies of the same depot antipsychotic at the equivalent dose on psychiatric outcomes and adverse effects. This study investigated differences in psychiatric outcomes and adverse effects between different frequencies of depot antipsychotics through a systematic review and meta-analysis. Read More

View Article
December 2018

A mouse model for intellectual disability caused by mutations in the X-linked 2'‑O‑methyltransferase Ftsj1 gene.

Biochim Biophys Acta Mol Basis Dis 2018 Dec 14. Epub 2018 Dec 14.

Department of Functional Genomics, Interfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, Felix-Hausdorff-Strasse 8, 17489 Greifswald, Germany.

Mutations in the X chromosomal tRNA 2'‑O‑methyltransferase FTSJ1 cause intellectual disability (ID). Although the gene is ubiquitously expressed affected individuals present no consistent clinical features beyond ID. In order to study the pathological mechanism involved in the aetiology of FTSJ1 deficiency-related cognitive impairment, we generated and characterized an Ftsj1 deficient mouse line based on the gene trapped stem cell line RRD143. Read More

View Article
December 2018

Dioclea violacea lectin ameliorates inflammation in the temporomandibular joint of rats by suppressing intercellular adhesion molecule-1 expression.

Biochimie 2018 Dec 14. Epub 2018 Dec 14.

Faculdade São Leopoldo Mandic, Instituto de Pesquisas São Leopoldo Mandic, Área de Imunologia, Campinas, Brazil. Electronic address:

Inflammation of temporomandibular joint (TMJ) tissues are the most common cause of pain conditions associated with temporomandibular disorders (TMDs). After a tissue and/or neural damage, the inflammatory response is characterized by plasma extravasation and leukocytes infiltration in the TMJ tissues, which in turn, release inflammatory cytokines cascades responsible for inflammatory pain. Lectins are glycoproteins widely distributed in nature that may exhibit anti-inflammatory properties. Read More

View Article
December 2018

Exploiting endogenous opioids: lessons learned from endomorphin 2 in the female rat.

Peptides 2018 Dec 14. Epub 2018 Dec 14.

Department of Neuroscience, School of Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA.

Effective management of chronic pain is demanded by ethical as well as medical considerations. Although opioid analgesics remain among the most effective pharmacotherapies for ameliorating many types of pain, their use is clouded by concerns regarding their addictive properties, underscored by the current epidemic of prescription opioid abuse and attendant deaths. Medicinal harnessing of endogenous opioid antinociception could provide a strategy for continuing to take advantage of the powerful antinociceptive properties of opioids while avoiding their abuse potential. Read More

View Article
December 2018

Risk and Risk Factors for Chronic Opioid Use Among Opioid-Naive Patients With Newly Diagnosed Musculoskeletal Pain in the Neck, Shoulder, Knee, or Low Back.

Ann Intern Med 2018 Dec 18. Epub 2018 Dec 18.

Stanford University School of Medicine, Stanford University, Stanford, California (J.M., E.S.).

View Article
December 2018

Role of serum levels of intraoperative brain natriuretic peptide for predicting acute kidney injury in living donor liver transplantation.

PLoS One 2018 17;13(12):e0209164. Epub 2018 Dec 17.

Department of Anesthesiology and Pain Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Background: Patients with end-stage liver disease frequently experience acute kidney injury (AKI) after living donor liver transplantation (LDLT). Serum levels of brain natriuretic peptide (BNP) have increasingly been accepted as a predictor of AKI in clinical settings. This study investigated the predictive role of intraoperative BNP levels in the early development of AKI after LDLT. Read More

View Article
December 2018

Assessment of degenerative cervical myelopathy differs between specialists and may influence time to diagnosis and clinical outcomes.

PLoS One 2018 17;13(12):e0207709. Epub 2018 Dec 17.

Academic Neurosurgery Unit, Department of Clinical Neurosurgery, University of Cambridge, Cambridge, United Kingdom.

Introduction: Degenerative Cervical Myelopathy [DCM] often presents with non-specific symptoms and signs. It progresses insidiously and leads to permanent neurological dysfunction. Decompressive surgery can halt disease progression, however significant delays in diagnosis result in increased disability and limit recovery. Read More

View Article
December 2018
1 Read

Familial episodic limb pain in kindreds with novel Nav1.9 mutations.

PLoS One 2018 17;13(12):e0208516. Epub 2018 Dec 17.

Department of Health and Environmental Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

We previously performed genetic analysis in six unrelated families with infantile limb pain episodes, characterized by cold-induced deterioration and mitigation in adolescence, and reported two new mutations p.R222H/S in SCN11A responsible for these episodes. As no term described this syndrome (familial episodic pain: FEP) in Japanese, we named it as". Read More

View Article
December 2018
1 Read

Effects of Structured Exercise Training in Children and Adolescents With Juvenile Idiopathic Arthritis.

Pediatr Phys Ther 2019 Jan;31(1):3-21

Program in Physical Therapy-retired (Dr Klepper), Department of Rehabilitation and Regenerative Medicine, Columbia University Medical Center, New York, New York; University of Utah Health (Dr Mano Khan), South Jordan, Utah; Lucille Packard Children's Hospital (Dr Klotz), Palo Alto, California; Westside Dance Physical Therapy (Dr Gregorek), New York, New York; Sloane Stecker Physical Therapy (Dr Chan), New York, New York; University of Colorado School of Medicine/Children's Hospital Colorado (Dr Sawade), Aurora, Colorado.

Purpose: To examine safety and efficacy of exercise training (ET) for juvenile idiopathic arthritis (JIA) to improve physical fitness, pain, functional capability, and quality of life.

Methods: Ovid Medline, PubMed, CINAHL, PEDro, and Web of Science were searched from 1995 to April 2018 to find English-language articles examining effects of ET in JIA, ages 4 to 21 years. Quality of evidence/strength of clinical recommendations were assessed using the Cochrane GRADE (Grading of Recommendations, Assessment, Development and Evaluation) system. Read More

View Article
January 2019

Opioid and Cannabis Co-Use among Adults with Chronic Pain: Relations to Substance Misuse, Mental Health, and Pain Experience.

J Addict Med 2018 Dec 13. Epub 2018 Dec 13.

Department of Psychology, University of Houston, Houston, TX (AHR, JB, DJP, MJV); Department of Psychology, Louisiana State University, Baton Rouge, LA (JDB); College of Nursing, Washington State University, Washington, DC (MFO); Department of Psychology, Syracuse University, New York, NY (JWD); Department of Behavioral Science, The University of Texas MD Anderson Cancer Center (MJZ); and HEALTH Institute, University of Houston, Houston, TX (MJZ).

Objectives: Opioid misuse constitutes a significant public health problem and is associated with a host of negative outcomes. Despite efforts to curb this increasing epidemic, opioids remain the most widely prescribed class of medications. Prescription opioids are often used to treat chronic pain despite the risks associated with use, and chronic pain remains an important factor in understanding this epidemic. Read More

View Article
December 2018

Encouraging a Bare Minimum While Striving for the Gold Standard: A Response to the Updated WHO-WFSA Guidelines.

Anesth Analg 2019 Jan;128(1):e12-e13

Journalism, Specialist Anaesthetist, Department of Anaesthesia and Perioperative Medicine, The Alfred Hospital and Monash University, Melbourne, Australia Consultant Anesthesiologist, King Faisal Hospital and Program Director, College of Medicine and Health Sciences University of Rwanda Consultant Anesthesiologist, Addis Ababa University, Ethiopia Consultant Anesthesiologist, Maputo Pain Clinic, Mozambique Anesthesiologist, Dalhousie University, Halifax, Canada Managing Director, Diamedica, United Kingdom Specialist Anaesthetist, Hobart, Tasmania Professor Emeritus, Queen's University, Departments of Anesthesiology, Pediatrics and Physiology, Kingston, Ontario, Canada Professor, Departments of Anesthesiology and Surgery Division of Ambulatory Surgery, Director, Vanderbilt Anesthesia Global Health & Development, Director, Vanderbilt Global Anesthesia Fellowship Affiliate Faculty, Vanderbilt Institute for Global Health, Vanderbilt University School of Medicine and Vanderbilt University Medical Center.

View Article
January 2019

Female Sexual Function and Sexual Well-being Before and After Breast Reduction: A Pilot Cross-sectional Study and Review of Literature.

Ann Plast Surg 2018 Dec 13. Epub 2018 Dec 13.

Dr Szczyt's Plastic Surgery Clinic, Warsaw, Poland.

Background: Breast reduction is one of the most frequently performed procedures in plastic surgery practice. Patients often undergo this procedure for not only aesthetic but also functional reasons because breast hypertrophy may hinder daily activities because of chronic spinal pain. Breast reduction has a documented impact on quality of life. Read More

View Article
December 2018

From A to D: A Unique Case Report of Recovery after Longitudinal Myelitis Related to Lupus.

Am J Phys Med Rehabil 2018 Dec 14. Epub 2018 Dec 14.

HealthPartners Neuroscience Center, St. Paul, MN, USA.

Longitudinal myelitis secondary to an acute flare of systemic lupus erythematosus (SLE) has been reported in the literature. There have been few published cases of complete functional recovery in patients with systemic lupus erythematosus related longitudinal myelitis (SLE-LM). Of those cases, none have described in detail the rehabilitation course of treatment. Read More

View Article
December 2018
1 Read

From poison to drug: new recipes discovered containing colchicine as a remedy for Podagra in Rome and Byzantium.

Clin Exp Rheumatol 2018 Nov 19. Epub 2018 Nov 19.

Institute of the History, Philosophy and Ethics of Medicine, Ulm University, Germany.

Objectives: In Antiquity, colchicine was used as a poison and as a remedy for Podagra. Research so far has revealed that the physician Alexander of Tralles was the first who used it in the 6th century AD. Alexander recommended a plant he called "Hermodaktylon", which takes off the pain in the feet immediately. Read More

View Article
November 2018

Frailty in seropositive rheumatoid arthritis patients of working age: a cross-sectional study.

Clin Exp Rheumatol 2018 Nov 19. Epub 2018 Nov 19.

Department of Social and Preventive Medicine, Centre of Public Health, Medical University of Vienna, Austria.

Objectives: The prevalence of frailty has been widely researched in the elderly population. However, data about people of working age are scarce. The aim of this paper was to assess the prevalence of prefrailty and frailty in rheumatoid arthritis (RA) patients of working age, and to assess factors associated with prefrailty/frailty. Read More

View Article
November 2018

Photodynamic therapy in infected venous and mixed leg ulcers: a pilot experience.

J Wound Care 2018 Dec;27(12):816-821

Consultant, Angiology Department, MD Barbantini Clinic, Lucca, Italy.

Objective:: To assess the tolerability and efficacy of photodynamic therapy (PDT) with RLP068, a novel phthalocyanine-derived photosensitiser, in controlling the bacterial load in different leg ulcers, due to vascular pathophysiology.

Method:: An observational study of patients with infected leg ulcers of different pathophysiology, admitted to the hospital for a skin grafting procedure, were included. All patients underwent two sessions of PDT at time zero and after 72 hours. Read More

View Article
December 2018
1 Read

Prophylaxis of chemotherapy-induced neutropenia and febrile neutropenia with lipegfilgrastim in 2489 cancer patients: final results from the non-interventional study NADIR.

Curr Med Res Opin 2018 Dec 17:1-27. Epub 2018 Dec 17.

i Gynecological Center Bonn-Friedensplatz , Bonn , Germany.

Objectives: The non-interventional study (NIS) NADIR (DRKS00005711) evaluated the effectiveness and safety of prophylaxis with lipegfilgrastim, a glycopegylated granulocyte-colony stimulating factor, in 2500 patients undergoing chemotherapy in routine clinical practice. Primary objective was the incidence of chemotherapy-induced severe neutropenia, febrile neutropenia (FN) and neutropenia-associated complications.

Methods: NADIR was a prospective NIS conducted in 201 study centers in Germany. Read More

View Article
December 2018

Effects of simultaneous steroid injection after percutaneous trigger finger release: a randomized controlled trial.

J Hand Surg Eur Vol 2018 Dec 17:1753193418813771. Epub 2018 Dec 17.

4 Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

The purpose of this study was to test the hypothesis that an improved outcome can be achieved by employing simultaneous steroid injection after percutaneous A1 pulley release. One hundred and twelve digits were randomized to either percutaneous A1 pulley release alone or release of the A1 pulley with a steroid injection. The visual analogue scale score for pain, modified patient global impression of improvement and modified Quinnell grade were assessed at 3 weeks and 3 months after surgery. Read More

View Article
December 2018

Cost-Utility Study of the Economics of Bunion Correction Surgery.

Foot Ankle Int 2018 Dec 17:1071100718815663. Epub 2018 Dec 17.

3 Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada.

Background:: Bunion correction surgery is a very common procedure to improve patients' pain and physical function attributable to a misaligned first metatarsophalangeal joint. The objective of this study was to apply a health utility framework to estimate the cost utility of bunion correction surgery.

Methods:: Patients were prospectively recruited from the population of patients seen in a lower-extremity orthopedic clinic and scheduled for isolated bunion surgery. Read More

View Article
December 2018

Adductor Canal Block Versus Femoral Nerve Block for Pain Control After Anterior Cruciate Ligament Reconstruction: A Prospective Randomized Trial.

Am J Sports Med 2018 Dec 17:363546518815874. Epub 2018 Dec 17.

Department of Orthopaedic Surgery, Henry Ford Health System, Detroit, Michigan, USA.

Background:: Femoral nerve block (FNB) is a commonly performed technique that has been proven to provide effective regional analgesia after anterior cruciate ligament (ACL) reconstruction. The adductor canal block (ACB) uses a similar sensory block around the knee while avoiding motor blockade of the quadriceps muscles.

Purpose/hypothesis:: The purpose of our study was to compare the efficacy of FNB versus ACB for pain control after ACL reconstruction. Read More

View Article
December 2018

Improvement in Functional Outcome Scores Despite Persistent Pain With 1 Year of Nonsurgical Management for Acetabular Labral Tears With or Without Femoroacetabular Impingement.

Am J Sports Med 2018 Dec 17:363546518814484. Epub 2018 Dec 17.

Department of Orthopaedic Surgery, Mass General Hospital, Boston, Massachusetts, USA.

Background:: Acetabular labral tears are increasingly recognized as a source of hip pain in a younger active population. Given the significant focus on surgical intervention, there has been limited investigation on the nonsurgical management and natural history of such injuries.

Hypothesis:: Patients undergoing nonsurgical treatment for symptomatic acetabular labral tears experience functional improvement based on patient-reported outcome measures over the course of 1 year. Read More

View Article
December 2018

Topical hyaluronic acid in the management of oral lichen planus: A comparative study.

J Investig Clin Dent 2018 Dec 17:e12385. Epub 2018 Dec 17.

Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, Jouf University, Sakaka, Saudi Arabia.

Aim: Oral lichen planus (OLP) is a chronic mucocutaneous disorder seen in clinical dental practice. Despite the progress in research and advances in knowledge, the successful management of OLP is still difficult to achieve. The aim of the present study was to compare the therapeutic effects of triamcinolone (TA) preparation (0. Read More

View Article
December 2018

Dancing Dorsal Quadrilaterals: A Novel Peripherally Induced Movement Disorder.

JAMA Neurol 2018 Dec 17. Epub 2018 Dec 17.

The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, Division of Neurology, University of Toronto, Toronto, Ontario, Canada.

Importance: Recognized peripherally induced movement disorders include the painful legs moving toes syndrome, postamputation dyskinesias, and belly dancer dyskinesias.

Objective: To introduce and characterize the dancing dorsal quadrilaterals, a novel peripherally induced movement disorder that predominantly affects dorsal quadrilateral muscles (trapezius and rhomboids) after upper spine instrumentation.

Design, Setting, And Participants: Between 1990 and 2015, a total of 4 patients who developed abnormal movements of the dorsal quadrilateral muscles after upper spine instrumentation were referred to movement disorders clinics at 3 academic medical centers in the United States, Canada, and Argentina. Read More

View Article
December 2018
1 Read

Supraspinal Mechanisms of Spinal Cord Stimulation for Modulation of Pain: Five Decades of Research and Prospects for the Future.

Anesthesiology 2018 Jul 18. Epub 2018 Jul 18.

From the Department of Anesthesiology and Critical Care Medicine (E.S., D.P.M., S.N.R., Y.G.) the Department of Neurological Surgery (Y.G.) School of Medicine, Johns Hopkins University, Baltimore, Maryland; and the Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden (B.L.).

The field of spinal cord stimulation is expanding rapidly, with new waveform paradigms asserting supraspinal sites of action. The scope of treatment applications is also broadening from chronic pain to include cerebral ischemia, dystonia, tremor, multiple sclerosis, Parkinson disease, neuropsychiatric disorders, memory, addiction, cognitive function, and other neurologic diseases. The role of neurostimulation as an alternative strategy to opioids for chronic pain treatment is under robust discussion in both scientific and public forums. Read More

View Article

The Safety and Effectiveness of Field Nitroglycerin in Patients with Suspected ST Elevation Myocardial Infarction.

Prehosp Emerg Care 2018 Dec 17:1-28. Epub 2018 Dec 17.

b Department of Emergency Medicine , Harbor-UCLA Medical Center and Los Angeles Biomedical Institute , Torrance , CA , USA ;

Objective: While widely used in the treatment of cardiac conditions, only limited data characterize out-of-hospital nitroglycerin (NTG) use. We sought to determine the safety of out-of-hospital sublingual NTG administered for suspected ST-segment elevation myocardial infarction (STEMI) and its effect on the patient's pain score.

Methods: We prospectively identified adult patients with suspected STEMI transported by paramedics to three PCI-capable hospitals in a large urban-suburban EMS system. Read More

View Article
December 2018

Adjuvant endocrine therapy side-effects among postmenopausal breast cancer patients in Malaysia.

Climacteric 2018 Dec 17:1-7. Epub 2018 Dec 17.

a Faculty of Pharmacy , Universiti Kebangsaan Malaysia , Kuala Lumpur , Malaysia.

Objective: This study was conducted to determine the prevalence and severity of menopausal symptoms and their associated risk factors among postmenopausal breast cancer patients receiving adjuvant endocrine therapy.

Methods: Postmenopausal breast cancer patients on endocrine therapy were recruited at three hospitals in Malaysia. Presence and severity of menopausal symptoms were determined using the Menopause Rating Scale. Read More

View Article
December 2018

No pain, no gain? Recovery and strenuousness of physical activity.

J Occup Health Psychol 2018 Dec 17. Epub 2018 Dec 17.

Behavioural Science Institute, Radboud University.

The present study aimed to advance insight in the role of leisure time physical activity (LTPA) in the recovery process, by focusing on the strenuousness of LTPA. It was proposed that-compared with less strenuous LTPA-more strenuous LTPA would show stronger positive relationships with recovery through higher levels of mental disengagement from stressors resulting from more strenuous LTPA. This hypothesis was examined in two studies, in which participants' positive and negative affective states were included as indicators of recovery. Read More

View Article
December 2018

Comparing anxiety and depression to obesity and smoking as predictors of major medical illnesses and somatic symptoms.

Health Psychol 2018 Dec 17. Epub 2018 Dec 17.

San Francisco VA Medical Center.

Objective: Anxiety and depression predict poor physical health longitudinally, but are neglected in primary care settings compared to other risk factors such as obesity and smoking. Further, anxiety has been less commonly studied than depression, and whether anxiety has unique predictive effects for physical health is unknown. We compared anxiety and depression to obesity and smoking as predictors of physical health indices and examined unique predictive effects of anxiety and depression. Read More

View Article
December 2018

Pelvic Girdle Pain Survey in Pregnancy: A Maternity Hospital Experience

Ir Med J 2018 Oct 11;111(9):829. Epub 2018 Oct 11.

Department of Obstetrics and Gynaecology, Galway University Hospital

View Article
October 2018

IgG4 Related Disease, A Case of Large Vessel Vasculitis

Ir Med J 2018 Oct 11;111(9):824. Epub 2018 Oct 11.

Rheumatology Department, Cork University Hospital

Aim This report describes a case of large vessel vasculitis highlighting diagnostic and therapeutic challenges. It describes the use of the B cell depleting agent Rituximab in this setting. This is the case of a 50 year old lady with bipolar disorder presenting with lower limb pain. Read More

View Article
October 2018

Clinical characteristics and location of lesions in patients with deep infiltrating endometriosis: using the revised Enzian classification

J Turk Ger Gynecol Assoc 2018 Dec 17. Epub 2018 Dec 17.

Department of General Surgery, Civil Hospital of Culiacán, Center for Research and Training in Health Sciences, Autonomous University of Sinaloa, Culiacán, Sinaloa, Mexico

Objective: To describe clinical characteristics and location of lesions in patients with deeply infiltrating endometriosis using the revised Enzian (rEnzian) classification.

Methods: Clinical records of 60 patients undergoing laparoscopy for deeply infiltrating endometriosis at Hospital Civil de Culiacán, Sinaloa and Hospital San Javier, Jalisco, México were reviewed. Age, body mass index (BMI), number of pregnancies, childbearing, previous abortions, laparoscopic suggestion (pelvic pain, bleeding, infertility), size and location of the lesions, were assessed according to rEnzian classification. Read More

View Article
December 2018

ADAM9 contributes to vascular invasion in pancreatic ductal adenocarcinoma.

Mol Oncol 2018 Dec 17. Epub 2018 Dec 17.

Faculty of Medicine, University of Freiburg, Germany.

A disintegrin and a metalloprotease (ADAM) 9 is a metzincin cell-surface protease with strongly elevated expression in solid tumors, including pancreatic ductal adenocarcinoma (PDAC). In this study, we performed immunohistochemistry (IHC) of a tissue microarray (TMA) to examine the expression of ADAM9 in a cohort of > 100 clinically-annotated PDAC cases. We report that ADAM9 is prominently expressed by PDAC tumor cells, and increased ADAM9 expression levels correlate with poor tumor grading (p = 0. Read More

View Article
December 2018

The Impact of Electrical Charge Delivery on Inhibition of Mechanical Hypersensitivity in Nerve-Injured Rats by Sub-Sensory Threshold Spinal Cord Stimulation.

Neuromodulation 2018 Dec 17. Epub 2018 Dec 17.

Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

Objectives: Spinal cord stimulation (SCS) represents an important neurostimulation therapy for pain. A new ultra-high frequency (10,000 Hz) SCS paradigm has shown improved pain relief without eliciting paresthesia. We aim to determine whether sub-sensory threshold SCS of lower frequencies also can inhibit mechanical hypersensitivity in nerve-injured rats and examine how electric charge delivery of stimulation may affect pain inhibition by different patterns of subthreshold SCS. Read More

View Article
December 2018

Selective MMP-13 inhibitors: promising agents for the therapy of Osteoarthritis.

Curr Med Chem 2018 Dec 17. Epub 2018 Dec 17.

Key Laboratory of Theoretical Organic Chemistry and Functional Molecule, Ministry of Education, Hunan Provincial Key Laboratory of Controllable Preparation and Functional Application of Fine Polymers, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, Hunan 411201. China.

Osteoarthritis (OA) is an age-related degenerative disease, which is characterized by the chronic joint pain, inflammation and the damage of joint cartilage. At present, steroidal drugs and nonsteroidal anti-inflammatory drugs (NSAIDS), selective cyclooxygenase-2 (COX-2) inhibitors, are the first-line drugs for the treatment of OA. However, these drugs could lead to some cardiovascular side effects. Read More

View Article
December 2018

The association of bike fitting with injury, comfort, and pain during cycling: An international retrospective survey.

Eur J Sport Sci 2018 Dec 15:1-8. Epub 2018 Dec 15.

e Applied Neuromechanics Group, Laboratory of Neuromechanics , Federal University of Pampa , Uruguaiana , Brazil.

Although bike fitting is recommended to help reduce injury risk, little empirical evidence exists to indicate an association between bike fitting and injury incidence. The aim of the study was to determine the effect of bike fitting on self-reported injury, comfort, and pain while cycling from a worldwide survey of cyclists. A total of 849 cyclists completed an online questionnaire between February and October 2016. Read More

View Article
December 2018

Insertion depth of nasotracheal tubes sized to fit the nostril: an observational study.

J Int Med Res 2018 Dec 16:300060518800105. Epub 2018 Dec 16.

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Yonsei-ro, Seodaemun-Gu, Seoul, Republic of Korea.

Objective: Nasotracheal (NT) intubation is commonly applied during head and neck surgery. However, improper tube size and depth may cause complications. In the current study, we investigated whether NT tubes are being appropriately used in terms of size and depth in adult patients. Read More

View Article
December 2018

How Grandparents Experience the Death of a Grandchild With a Life-Limiting Condition.

J Fam Nurs 2018 Dec 17:1074840718816808. Epub 2018 Dec 17.

2 Lancaster University, UK.

Traditionally, family-focused care extends to parents and siblings of children with life-limiting conditions. Only a few studies have focused on the needs of grandparents, who play an important role in the families of children with illness and with life-limiting conditions, in particular. Interpretative phenomenological analysis was used as the methodological framework for the study. Read More

View Article
December 2018

Effectiveness of custom-made foot orthoses in patients with rheumatoid arthritis: a randomized controlled trial.

Clin Rehabil 2018 Dec 17:269215518819118. Epub 2018 Dec 17.

1 Department of Podiatry, University of Seville, Seville, Spain.

Objective:: To determine the effect of custom-made foot orthoses versus placebo insoles on pain, disability, foot functionality, and quality of life.

Design:: Double-blinded randomized controlled trial.

Setting:: University Podiatric Clinical Area. Read More

View Article
December 2018

Gender difference of symptoms of acute coronary syndrome among Chinese patients: a cross-sectional study.

Eur J Cardiovasc Nurs 2018 Dec 17:1474515118820485. Epub 2018 Dec 17.

5 LinYi People's Hospital, Nursing Administrative Department, China.

Background:: The incidence of acute coronary syndrome is increasing in China.

Objective:: To investigate gender differences in Chinese patients' acute coronary syndrome symptoms, attribution of symptoms and reasons for seeking medical service.

Methods:: This was a cross-sectional, multicentre study. Read More

View Article
December 2018

Bupivacaine-induced cardiotoxicity and lipid emulsion.

Authors:
D H Lim J-T Sohn

Hum Exp Toxicol 2018 Dec 16:960327118819042. Epub 2018 Dec 16.

2 Department of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Gyeongsang National University Hospital, Jinju-si, Gyeongsangnam-do, Republic of Korea.

View Article
December 2018

Patient education in dental medicine: a review of the literature.

Eur J Dent Educ 2018 Dec 17. Epub 2018 Dec 17.

Health education laboratory EA3412 University Paris 13, Sorbonne Paris Cité, 74 rue Marcel Cachin, 93017, Bobigny, Cedex, France.

Introduction / Background: In odontology, chronic diseases and chronic conditions (such as chronic periodontitis, temporomandibular disorders, chronic orofacial pain) justify patient education to self-care. This strategy of secondary or tertiary prevention, even if officially recognized, is still less known compared to health education, a form of primary prevention. We wanted to make the point of recent studies devoted to patient education. Read More

View Article
December 2018
1 Read
  • Page 1 of 15164