1,978 results match your criteria Pain Physician[Journal]


Responsible, Safe, and Effective Use of Antithrombotics and Anticoagulants in Patients Undergoing Interventional Techniques: American Society of Interventional Pain Physicians (ASIPP) Guidelines.

Pain Physician 2019 Jan;22(1S):S1-S74

Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Background: Interventional pain management involves diagnosis and treatment of chronic pain. This specialty utilizes minimally invasive procedures to target therapeutics to the central nervous system and the spinal column. A subset of patients encountered in interventional pain are medicated using anticoagulant or antithrombotic drugs to mitigate thrombosis risk. Read More

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January 2019
2 Reads
3.542 Impact Factor

Responsible, Safe, and Effective Use of Biologics in the Management of Low Back Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines.

Pain Physician 2019 Jan;22(1S):S1-S74

Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Background: Regenerative medicine is a medical subspecialty that seeks to recruit and enhance the body's own inherent healing armamentarium in the treatment of patient pathology. This therapy's intention is to assist in the repair, and to potentially replace or restore damaged tissue through the use of autologous or allogenic biologics. This field is rising like a Phoenix from the ashes of underperforming conventional therapy midst the hopes and high expectations of patients and medical personnel alike. Read More

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January 2019
1 Read
3.542 Impact Factor

Comparison of Lateral Branched Pulsed Radiofrequency Denervation and Intraarticular Depot Methylprednisolone Injection for Sacroiliac Joint Pain: Inquiry for Additional Investigation.

Pain Physician 2019 Jan;22(1):E53-E54

Department of Anesthesiology Harbor UCLA Medical Center Torrance, California.

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January 2019

Vitamin B12 as a Treatment for Pain.

Pain Physician 2019 Jan;22(1):E45-E52

Desert Clinic Pain Institute, Rancho Mirage, CA.

Background: First isolated as cyanocobalamin in 1948, vitamin B12 has been explored for pain treatment almost since its discovery. With the advent of the opioid epidemic, safer treatments for pain are needed.

Objectives: Our objective was to compile the latest information on potential mechanisms from animal studies and clinical trial data on vitamin B12 for the treatment of pain conditions. Read More

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January 2019
1 Read

High Level of Childhood Trauma Predicts a Poor Response to Spinal Cord Stimulation in Chronic Neuropathic Pain.

Pain Physician 2019 Jan;22(1):E37-E44

Neurosurgery of KUH NeuroCenter, Kuopio University Hospital, and Faculty of Health Sciences, School of Medicine, Institute of Clinical Medicine, University of Eastern Finland.

Background: Spinal cord stimulation (SCS) relieves pain by delivering doses of electric current to the dorsal column of the spinal cord and has been found to be most effective in the treatment of neuropathic pain. Psychological distress is a significant risk factor for the development of chronic pain and has been found to affect the outcome of SCS. Childhood trauma is a risk factor for chronic pain, but has not previously been studied in SCS patients. Read More

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January 2019
4 Reads

Nerve Entrapment Headaches at the Temple: Zygomaticotemporal and/or Auriculotemporal Nerve?

Pain Physician 2019 Jan;22(1):E15-E36

Seattle Children's Hospital University of Washington, Seattle, WA.

Background: Temple headaches are common, yet the anatomic etiology of headaches in this region is often confusing. One possible cause of temple headaches is dysfunction of the auriculotemporal nerve (ATN), a branch of the third division of the trigeminal nerve. However, the site of pain is often anterior to the described path of the ATN, and corresponds more closely to a portion of the path of a small branch of the second division of the trigeminal nerve called the zygomaticotemporal nerve (ZTN). Read More

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January 2019
1 Read

How Does Self-Efficacy Influence Pain Perception, Postural Stability and Range of Motion in Individuals with Chronic Low Back Pain?

Pain Physician 2019 Jan;22(1):E1-E13

Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Autónoma de Madrid, Aravaca, Madrid, Spain; Motion in Brains Research Group, Centro Superior de Estudios Universitarios La Salle; Universidad Autónoma de Madrid, Aravaca, Madrid, Spain; Institute of Neuroscience and Craniofacial Pain (INDCRAN). Madrid, Spain; Hospital La Paz Institute for Health Research, IdiPAZ. Madrid, Spain.

Background: Low back pain (LBP) is the most prevalent musculoskeletal problem among adults. Individuals with chronic LBP (CLBP) can present a psychological disorder and a lack of pain self-efficacy.

Objectives: The objective of this study was to compare the process of repetition-induced summation of activity-related pain, the lumbar range of motion, and the postural stability of patients with non-specific LBP (NSLBP) based on their level of self-efficacy. Read More

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January 2019

Relationship Between Decreased Subcalcaneal Fat Pad Thickness and Plantar Heel Pain. A Case Control Study.

Pain Physician 2019 Jan;22(1):109-116

Department of Nursing and Physical Therapy, Institute of Biomedicine, University of León, Ponferrada, León, Spain.

Background: Heel pain is one of the most frequent complaints in medical clinical practice for conditions affecting the feet during weight-bearing tasks.

Objective: The goal of this study was to measure and compare the thickness of the fat pad in a sample of patients with current unilateral heel pain and patients without unilateral heel pain with normalized reference parameters.

Study Design: This was an observational case-control study. Read More

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January 2019
5 Reads

OPRM1 Gene Interaction with Sleep in Chronic Pain Patients Treated with Opioids.

Pain Physician 2019 Jan;22(1):97-107

Pain Unit, Health Department of Alicante-General Hospital, Alicante, Spain; Neuropharmacology on Pain (NED), Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation), Alicante, Spain; Clinical Pharmacology Unit, Health Department of Alicante-General Hospital, Alicante, Spain.

Background: The experience of chronic non-cancer pain (CNCP) is one of the most common reasons individuals seek medical attention. Patients with CNCP frequently experience concomitant sleep-related problems.

Objectives: The aim was to evaluate sleep problems in opioid naïve CNCP patients, before and after opioid titration, analyzing the influence of OPRM1 gene variants. Read More

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January 2019

Transforaminal Epiduroscopy in Patients with Failed Back Surgery Syndrome.

Pain Physician 2019 Jan;22(1):89-95

Pain Clinic, Hospital Universitario Sanitas La Moraleja, Madrid, Spain; Consultores en Dolor, Madrid, Spain.

Background: Epiduroscopy is a useful diagnostic and therapeutic tool for managing failed back surgery syndrome (FBSS). The conventional approach is via either the sacral hiatus or the interlaminar. Major causes of FBSS include epidural fibrosis, disc herniation, and stenosis. Read More

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January 2019
4 Reads

Full-Endoscopic Lumbar Fusion Outcomes in Patients with Minimal Deformities: A Retrospective Study of Data Collected Between 2011 and 2015.

Pain Physician 2019 Jan;22(1):75-88

Spine Institute Northwest, Bothell, Washington.

Background: Open transforaminal lumbar interbody fusion (TLIF) is the gold standard treatment for back pain due to degenerative disc disease and lumbar instability. Traditional open TLIF has been associated with extensive tissue dissection, excessive blood loss, and slow recovery time. Full-endoscopic transforaminal lumbar interbody fusion (FE-TLIF) is an evolving treatment. Read More

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January 2019

The Impact of Local Steroid Administration on the Incidence of Neuritis following Lumbar Facet Radiofrequency Neurotomy.

Pain Physician 2019 Jan;22(1):69-74

Weill Cornell Medical College, Center for Comprehensive Spine Care, Department of Rehabilitation Medicine, New York, NY.

Background: Pain arising from the lumbar facet joints is a common cause of axial back pain in adults. Radiofrequency neurotomy (RFN) of the medial branches of the spinal dorsal rami has been used as a treatment option. The most common side effect is transient, localized, burning, neuritic-type pain, termed post-neurotomy neuritis (PNN). Read More

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January 2019

Effectiveness Analysis of Percutaneous Kyphoplasty Combined with Zoledronic Acid in Treatment of Primary Osteoporotic Vertebral Compression Fractures.

Pain Physician 2019 Jan;22(1):63-68

Department of Spine Surgery, Wuhan No. 1 Hospital, Wuhan, China.

Objective: To investigate the therapeutic effectiveness of percutaneous kyphoplasty (PKP) combined with zoledronic acid in treatment of primary osteoporotic vertebral compression fractures.

Study Design: A perspective cohort study was conducted at a single institution for patients, who received PKP operation due to primary osteoporotic vertebral compression fracture between January 2014 and January 2015.

Setting: According to whether they received postoperative zoledronic acid or not, patients were divided into treatment or control groups, with 30 randomly-selected cases per group. Read More

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January 2019

Effectiveness of Exercise Therapy and Manipulation on Sacroiliac Joint Dysfunction: A Randomized Controlled Trial.

Pain Physician 2019 Jan;22(1):53-61

Department of Sports medicine and Exercise Medicine, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

Background: The sacroiliac joint dysfunction (SIJD) has been found to be the primary culprit for lower back pain (LBP), but it is still overlooked and treated as LBP. There are no guidelines or appropriate therapeutic protocols for SIJD. Thus, there is a need for an effective treatment strategy for SIJD. Read More

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January 2019

Posterior Cervical Foraminotomy Via Full-Endoscopic Versus Microendoscopic Approach for Radiculopathy: A Systematic Review and Meta-analysis.

Pain Physician 2019 Jan;22(1):41-52

Department of Spine, The Second Xiangya Hospital of Central South University, Changsha, Hunan China.

Background: Recently posterior cervical foraminotomy (PCF) performed using a minimally-invasive surgery (MIS) approach for cervical radiculopathy due to lateral disc herniation or osseous foraminal stenosis has gained popularity. As 2 dominating MIS techniques, whether FE-PCF or MI-PCF provides superior clinical outcomes remains controversial.

Objectives: To compare clinical success rate, overall incidence of complications and reoperation rate between full-endoscopic posterior cervical foraminotomy (FE-PCF) and microendoscopic posterior cervical foraminotomy (MI-PCF) for cervical radiculopathy. Read More

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January 2019
1 Read

Sacroiliac Joint Fusion Methodology - Minimally Invasive Compared to Screw-Type Surgeries: A Systematic Review and Meta-Analysis.

Pain Physician 2019 Jan;22(1):29-40

MedAware Systems, Inc., Broomfield, CO.

Background: Sacroiliac (SI) joint fusion represents a unique area of orthopedic surgery with procedural literature dating to the early 1920s, showing limited innovation in either technique or hardware over the last 90 years. Recent improvements in the diagnosis and treatment of SI joint dysfunction warrant comparisons to older surgical techniques.

Objective: To evaluate treatment efficacies and patient outcomes associated with minimally invasive joint fusion in comparison to screw-type surgeries. Read More

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January 2019
3.542 Impact Factor

Unilateral Versus Bilateral Balloon Kyphoplasty for Osteoporotic Vertebral Compression Fractures: A Systematic Review of Overlapping Meta-analyses.

Pain Physician 2019 Jan;22(1):15-28

Peking University Sixth Hospital, Beijing, China.

Background: There have been many meta-analyses and systematic reviews that have discussed the differences between unilateral and bilateral balloon kyphoplasty. However, their conclusions regarding the efficacy and safety of bilateral balloon kyphoplasty in the treatment of osteoporotic vertebral compression fractures (OVCFs) are discordant.

Objective: We attempted to select the best evidence review to determine the differences between unilateral and bilateral balloon kyphoplasty, and we wanted to determine the best treatment approach for OVCFs. Read More

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January 2019
1 Read

A Systematic Review of Devices and Techniques that Objectively Measure Patients' Pain.

Pain Physician 2019 Jan;22(1):1-13

Department of Radiation Oncology, University Medical Center Utrecht, The Netherlands.

Background: Assessment of pain is important in daily clinical practice and as an endpoint in clinical studies. Because pain perception is highly subjective, pain measurement is complex. Self-rating pain scales are currently of great importance but have limitations. Read More

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January 2019

Detailed Parameters and Accurate Description are Needed for Pulsed Radiofrequency.

Authors:
Li Song Weidong Yan

Pain Physician 2018 11;21(6):E667-E668

Sichuan University West China Hospital, Department of Pain Management, Chengdu, Sichuan Province, China.

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November 2018

Fluoroscopically-Guided Cervical Zygapophyseal Therapeutic Joint Injections May Reduce the Need for Radiofrequency.

Pain Physician 2018 11;21(6):E661-E665

The Orthopedic Clinic Association, Phoenix, AZ.

Background: There is a paucity of literature studying therapeutic intraarticular zygapophyseal (commonly referred to as facet) joint injections in the atraumatic patient population. As a result of this, intraarticular injections have been dismissed as a possible treatment for cervical zygapophyseal joint-mediated pain. Radiofrequency neurotomy (RFN) is currently the accepted treatment for facet joint neck pain. Read More

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November 2018

A Novel Technique of Saddle Rhizotomy Using Thermal Radiofrequency for Intractable Perineal Pain in Pelvic Malignancy: A Pilot Study.

Pain Physician 2018 11;21(6):E651-E660

Department of Anesthesia and Pain Management, National Cancer Institute, Cairo University, Cairo, Egypt.

Background: The prevalence of pain in advanced pelvic cancer may reach up to 95%. Control of such pain is often difficult owing to a variety of neuroanatomical and functional peculiarities. Different modalities have been utilized to treat this pain including saddle chemical rhizolysis with the potential for jeopardizing the neural control of the sphincters. Read More

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November 2018
9 Reads

Safety and Effectiveness of Transforaminal Epiduroscopic Laser Ablation in Single Level Disc Disease: A Case-Control Study.

Pain Physician 2018 11;21(6):E643-E650

Department of Neurosurgery, Spine and Spinal Cord Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Background: The non-operative treatment of herniated intervertebral discs has long been a fundamental challenge. A novel technique of laser ablation to ablate the nucleus pulposus under a transforaminal epiduroscope (TELA system, Lutronics, Seoul, Republic of Korea) was recently developed.

Objective: The purpose of this study was to evaluate the safety and effectiveness of transforaminal epiduroscopic laser ablation (TELA) for selective ablation of the nucleus pulposus in single-level disc disease. Read More

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November 2018
7 Reads

Recurrent Headache Increases Blood-Brain Barrier Permeability and VEGF Expression in Rats.

Pain Physician 2018 11;21(6):E633-E642

Laboratory Research Center, The First Affiliated Hospital of Chongqing Medical University, Chong Qing, China.

Background: The blood-brain barrier (BBB) is an important anatomical structure of the central nervous system (CNS) that limits the penetration of a variety of substances from the blood into the parenchyma. Dysfunction of the BBB is involved in various CNS disorders, including stroke, inflammation, and pain. However, the evidence concerning its role in migraine is insufficient. Read More

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November 2018
1 Read

Association Between Socio-Demographic and Health Functioning Variables Among Patients with Opioid Use Disorder Introduced by Prescription: A Prospective Cohort Study.

Pain Physician 2018 11;21(6):E623-E632

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada; Population Genomic Program, Chanchalani Research Centre, McMaster University, Hamilton, Canada; Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Canada; Peter Boris Centre for Addictions Research, Canada.

Background: Prescription opioid misuse in Canada has become a serious public health concern and has contributed to Canada's opioid crisis. There are thousands of Canadians who are currently receiving treatment for opioid use disorder, which is a chronic relapsing disorder with enormous impact on individuals and society.

Objectives: The aim of this study was to compare the clinical and demographic differences between cohorts of patients who were introduced to opioids through a prescription and those introduced to opioids for non-medical purposes. Read More

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November 2018
1 Read

Fundamental Considerations for Genetically-Guided Pain Management with Opioids Based on CYP2D6 and OPRM1 Polymorphisms.

Pain Physician 2018 11;21(6):E611-E621

Genomas Inc., Hartford, CT.

Background: A major challenge for effective pharmacotherapy in pain management is to provide the drug best suited to the patient's innate characteristics.

Objective: The article illustrates pharmacogenetic principles to optimize treatments for patients and increase the likelihood of pain relief without dependence. Genetic variances are particularly relevant to opioid drugs used in pain control, and can now be harvested for predictive clinical decision support. Read More

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November 2018
2 Reads

Exploring the Role of Chronic Pain Clinics: Potential for Opioid Reduction.

Pain Physician 2018 11;21(6):E603-E610

Department of Anesthesiology, University of Arizona, Tucson, AZ; Department of Pharmacology, University of Arizona, Tucson, AZ.

Background: The management of chronic nonmalignant pain with high-dose opioids has partially contributed to the current opioid epidemic, with some responsibility shared by chronic pain clinics. Traditionally, both primary care providers and patients used chronic pain clinics as a source for continued medical management of patients on high-dose opioids, often resulting in tolerance and escalating doses. Although opioids continue to be an important component of the management of some chronic pain conditions, improvement in function and comfort must be documented. Read More

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November 2018

Evaluation of Primary Care Physician Chronic Pain Management Practice Patterns.

Pain Physician 2018 11;21(6):E593-E602

School of Pharmacy and Graduate School of Pharmaceutical Sciences Division of Pharmaceutical, Administrative and Social Sciences Duquesne University, Duquesne University.

Background: The management of chronic pain is complex and often involves the integration of multiple clinical, humanistic, and economic factors. Primary care physicians (PCPs) are often at the forefront of managing chronic pain and often initiate pharmacological pain management therapy. To date little is known surrounding the pain management practices of PCPs. Read More

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November 2018
10 Reads

Clinical Benefits of Direct-to-Definitive Testing for Monitoring Compliance in Pain Management.

Pain Physician 2018 11;21(6):E583-E592

Department of Pathology, Brigham and Women's Hospital, Boston, MA; Harvard Medical School, Boston, MA.

Background: The technical advantages of direct-to-definitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) urine testing for monitoring patient compliance in pain management are well known. However, the design and implementation of LC-MS/MS methods are more controversial, including factors such as determining appropriate cutoffs, specimen processing (e.g. Read More

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November 2018

The Effects of Radiofrequency Neurotomy Using a Strip-Lesioning Device on Patients with Sacroiliac Joint Pain: Results from a Single-Center, Randomized, Sham-Controlled Trial.

Pain Physician 2018 11;21(6):607-618

Pain and Anaesthesia Research Centre, St. Bartholomew's Hospital, United Kingdom.

Background: Radiofrequency neurotomy (RFN) is a therapy aimed at providing lasting back pain relief for sacroiliac joint (SIJ) pain. A recent advancement in RFN is a strip lesioning technique that involves placement of a single curved electrode and a 3-pole design that facilitates the creation of 5 overlapping lesions. These lesions form one long strip lesion accessible through a single entry point, without the need for multiple punctures. Read More

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November 2018
2 Reads

Percutaneous Epidural Adhesiolysis Using Inflatable Balloon Catheter and Balloon-less Catheter in Central Lumbar Spinal Stenosis with Neurogenic Claudication: A Randomized Controlled Trial.

Pain Physician 2018 11;21(6):593-606

Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Background: When conventional interventional procedures fail, percutaneous epidural adhesiolysis (PEA), which has moderate evidence for successful treatment of lumbar spinal stenosis (LSS), has been recommended over surgical treatments. In a previous study, we demonstrated the efficacy of a newly developed inflatable balloon catheter for overcoming the access limitations of pre-existing catheters for patients with severe stenosis or adhesions.

Objectives: This study compared the treatment response of combined PEA with balloon decompression and PEA only in patients with central LSS over 6 months of follow-up. Read More

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November 2018
1 Read

Treatment of Chemotherapy-Induced Peripheral Neuropathy: Systematic Review and Recommendations.

Pain Physician 2018 11;21(6):571-592

University of Texas, MD Anderson Cancer Center, Houston, TX.

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a commonly encountered disease entity following chemotherapy for cancer treatment. Although only duloxetine is recommended by the American Society of Clinical Oncology (ASCO) for the treatment of CIPN in 2014, the evidence of the clinical outcome for new pharmaceutic therapies and non-pharmaceutic treatments has not been clearly determined.

Objective: To provide a comprehensive review and evidence-based recommendations on the treatment of CIPN. Read More

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November 2018

A Network Meta-Analysis to Compare the Efficacy of Steroid and Antiviral Medications for Facial Paralysis from Bell´s Palsy.

Pain Physician 2018 11;21(6):559-569

Department of Neurology, the Second Hospital of Jilin University, Changchun, Jilin, China.

Background: Facial paralysis is the most common cranial nerve injury. Bell's palsy is the name commonly used to describe an acute peripheral facial paralysis of unknown origin. The annual incidence of Bell's palsy is 20-30 cases per 100,000 persons, regardless of age and gender. Read More

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November 2018
2 Reads

Are Pain Beliefs, Cognitions, and Behaviors Influenced by Race, Ethnicity, and Culture in Patients with Chronic Musculoskeletal Pain: A Systematic Review.

Pain Physician 2018 11;21(6):541-558

Univeristy of Antwerp, Faculty of medicine and health sciences, Department of Rehabilitation Sciences and Physiotherapy, Antwerp, Belgium.

Background: Chronic pain has been considered as a biopsychosocial condition in which cognitive and emotional factors as well as biological factors significantly affect perception of pain. Race, ethnicity and culture have a crucial impact on illness beliefs, health care preferences, help-seeking behaviors, and acceptance of medical interventions.

Objectives: The aim of the present study was to systematically review the current evidence regarding the racial, ethnic and cultural alterations and differences in pain beliefs, cognitions, and behaviors in patients with chronic musculoskeletal pain (MSKP). Read More

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November 2018
1 Read

Do Regenerative Medicine Therapies Provide Long-Term Relief in Chronic Low Back Pain: A Systematic Review and Metaanalysis.

Pain Physician 2018 11;21(6):515-540

Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Background: Several cell-based therapies have been proposed in recent years the management of low back pain, including the injection of medicinal signaling cells or mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP). However, there is only emerging clinical evidence to support their use at this time.

Objective: To assess the effectiveness of MSCs or PRP injections in the treatment of low back and lower extremity pain. Read More

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November 2018
1 Read

Reframing the Role of Neuromodulation Therapy in the Chronic Pain Treatment Paradigm.

Pain Physician 2018 11;21(6):507-513

Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Blaustein Pain Treatment Center, Johns Hopkins Hospital, Baltimore MD.

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November 2018
1 Read

Re: Neuropathic Pain in Acute and Subacute Neuropathies: A Systematic Review.

Authors:
Lu Chen Ling Ye

Pain Physician 2018 09;21(5):E581-E582

Department of Pain Management, West China Hospital, Sichuan University, Chengdu, Sichuan Province, P.R.China.

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September 2018
1 Read

Mexiletine Usage in a Chronic Pain Clinic: Indications, Tolerability, and Side Effects.

Pain Physician 2018 09;21(5):E573-E579

Department of Anesthesiology, Pain Management & Perioperative Medicine; Henry Ford Health System; Detroit, MI.

Background: Intravenous lidocaine has multiple applications in the management of acute and chronic pain. Mexiletine, an oral lidocaine analogue, has been used in a number of chronic pain conditions although its use is not well characterized.

Objectives: To report our experience using mexiletine in a chronic pain population, specifically looking at tolerability, side effects, and EKG changes. Read More

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September 2018
3 Reads

Feasibility of Percutaneous Robot-Assisted Epiduroscopic System.

Pain Physician 2018 09;21(5):E565-E571

Healthcare Robotics Group, Korea Institute of Science and Technology, Korea.

Background: Endoscopy has replaced open surgery, especially in spinal surgery. Among them, image-guided epiduroscopy allows pain generators to be identified, including epidural adhesion, fibrotic tissues, root compression, and spinal stenosis. However, the heavy lead apron worn by pain physicians to avoid exposure to radiation can induce occupational hazards, such as orthopedic complications and radiation-induced cancer. Read More

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September 2018
1 Read

Contribution of Spinal PKCγ Expression to Short- and Long-lasting Pain Behaviors in Formalin-induced Inflamed Mice.

Pain Physician 2018 09;21(5):E555-E564

Department of Anesthesiology, Fuzhou General Hospital of PLA, Fuzhou, PR China.

Background: Over-expression of spinal protein kinase Cγ(PKCγ) contributes to the induction of persistent bilateral hyperalgesia following inflammatory injury, yet the role of spinal PKCγ in short- and long-lasting pain behavior is poorly understood.

Objective: This study aimed to characterize the contribution of spinal PKCγ to spontaneous pain and long-lasting bilateral hyperalgesia in formalin-induced inflamed mice using pharmacological inhibition.

Study Design: Laboratory animal study. Read More

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September 2018
2 Reads

Patients' Perceptions of Chronic Pain During the Economic Crisis: Lessons Learned from Greece.

Pain Physician 2018 09;21(5):E533-E543

2nd Department of Anesthesiology, School of Medicine, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.

Background: Chronic pain is well known to be influenced by various social factors; however, the impact of financial issues on pain has not been extensively studied.

Objective: The aim of this study was to investigate the impact of the economic crisis on pain and quality of life in Greek patients suffering from chronic pain.

Study Design: The study employed a prospective, open-label design. Read More

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September 2018
7 Reads

Ionizing Radiation Dose Exposure to the Ocular Region of Pain Physicians During C-arm Guided Pain Interventions.

Pain Physician 2018 09;21(5):E523-E532

South Infirmary Victoria University Hospital, Cork, Ireland.

Background: The growth of interventional pain medicine in recent years has resulted in more procedures being carried out under fluoroscopic guidance. The proximity of the pain physician (PP) to ionization radiation (IR) potentially increases the risk of radiation exposure to the ocular region. A European directive has reduced the limits of occupational ocular dose 7. Read More

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September 2018
11 Reads

Enhanced Pain Sensitivity with Systemic Ultrastructural Changes of the Nervous Systems after Cobra Venom Injection is Reversed by Electroacupuncture Treatment.

Pain Physician 2018 09;21(5):E509-E521

University of Pittsburgh School of Medicine, Pittsburg, PA.

Background: Electroacupuncture (EA) has been proved to be effective in treating certain neuropathic pain conditions. The mechanisms of pain relief by EA are not fully understood. There have been sporadic reports of damage in the peripheral nervous system (PNS) and regions of the central nervous system (CNS) at the ultrastructural level following peripheral nerve injury. Read More

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September 2018
1 Read

Comparison of 3 Approaches to Percutaneous Epidural Adhesiolysis and Neuroplasty in Post Lumbar Surgery Syndrome.

Pain Physician 2018 09;21(5):E501-E508

Algology Division, Department of Anesthesia, Akdeniz University, Antalya, Turkey.

Background: Percutaneous epidural adhesiolysis and neuroplasty (PEAN) has been proven to be safe and effective in treating different spine pathologies, in particular post lumbar surgery syndrome (PLSS).

Objectives: The purpose of this study was to compare the efficacy and complication rates of the 3 different PEAN anatomical approaches (caudal, S1 foraminal, and L5-S1 transforaminal) used to treat PLSS.

Study Design: This study used a case control, blind study. Read More

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September 2018

Variations in Interlaminar Epidural Steroid Injection Practice Patterns by Interventional Pain Management Physicians in the United States.

Pain Physician 2018 09;21(5):E493-E499

Department of Anesthesiology, Perioperative Care and Pain Medicine, New York University Langone Health, New York, NY.

Background: Previous surveys have identified variations in practice patterns related to epidural steroid injections. Since then, the United States Food and Drug Administration (FDA) has required the addition of drug warning labels for injectable corticosteroids. Updated evidence, as well as scrutiny from regulatory agencies, may affect practice patterns. Read More

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September 2018
3 Reads

Earlier Vertebroplasty for Osteoporotic Thoracolumbar Compression Fracture May Minimize the Subsequent Development of Adjacent Fractures: A Retrospective Study.

Pain Physician 2018 09;21(5):E483-E491

Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan; School of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.

Background: Percutaneous vertebroplasty (PVP) is widely used to treat osteoporotic vertebral compression fractures (OVCFs). The influence of timing (early vs. late) of PVP on the development of adjacent vertebral fractures (AVF) has rarely been discussed. Read More

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September 2018
3 Reads

A Retrospective Review of Spinal Radiofrequency Neurotomy Procedures in Patients with Metallic Posterior Spinal Instrumentation - Is it Safe?

Pain Physician 2018 09;21(5):E477-E482

Rutgers New Jersey Medical School Department of Pain Management, Newark, NJ.

Background: Recent studies have shown that medial branch radiofrequency neurotomy (RFN) procedures done at the level of a pedicle screw can increase pedicle screw temperature, and it has been speculated that pedicle screw heating may cause thermal injury. There has been a limited amount of investigation into the real-world safety profile of RFN procedures in patients with pedicle screws.

Objectives: We aim to demonstrate that the occurrence of serious adverse events is rare for a medial branch RFN procedure completed at a level with metallic spinal hardware when performed according to the Spine Intervention Society practice standards. Read More

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September 2018
2 Reads

Low Volume Neurolytic Retrocrural Celiac Plexus Block for Visceral Cancer Pain: Retrospective Review of 507 Patients with Severe Malignancy Related Pain Due to Primary Abdominal Cancer or Metastatic Disease.

Pain Physician 2018 09;21(5):497-504

Department of Anesthesiology and Pain Management, JHS Hospital of Cook County, Chicago, IL.

Background: Abdominal pain from primary cancer or metastatic disease is a significant cause of pain for patients undergoing treatment for the disease. Patient's pain may be resistant to conventional analgesics. The need for timely pain relief in order to facilitate further care in the cancer treatment plan should be a priority. Read More

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September 2018

Comparison of Efficacy of Lateral Branch Pulsed Radiofrequency Denervation and Intraarticular Depot Methylprednisolone Injection for Sacroiliac Joint Pain.

Pain Physician 2018 09;21(5):489-496

North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, India.

Background: Sacroiliac joint dysfunctional pain has always been an enigma to the pain physician, whether it be the diagnosis or the treatment. Diagnostic blocks are the gold standard way to diagnose this condition. Radiofrequency neurotomy of the nerves supplying the sacroiliac joint has shown equivocal results due to anatomical variation. Read More

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September 2018
2 Reads