1,749 results match your criteria POEMS Syndrome
Am J Hematol 2018 Dec 12. Epub 2018 Dec 12.
Department of Lymphoma and Myeloma, MD Anderson Cancer, Houston, TX 77030.
Can J Ophthalmol 2018 Dec 7;53(6):e233-e236. Epub 2018 Jul 7.
Chinese PLA General Hospital, Beijing, P. R. China. Electronic address:
J Neurol 2018 Nov 29. Epub 2018 Nov 29.
Department of Neurology, Royal Free Hospital, Pond Street, London, NW3 2QG, UK.
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes) is a rare paraneoplastic syndrome, caused by a plasma cell proliferative disorder, which is most commonly lambda restricted. The neurological hallmark, which forms one of the mandatory criteria for diagnosis, is a subacute onset demyelinating neuropathy, which can be rapidly disabling and painful. A number of multi-system features are also characteristic of this disorder, and certainly not restricted to those included in its acronym, which though limited, remains a useful and memorable name, helping distinguish POEMS syndrome from other paraproteinaemic neuropathies. Read More
Psychiatr Danub 2018 Nov;30(Suppl 7):648
"Psychiatric Studies Center" (Cen.Stu.Psi.), Piazza Portici, 11 - 25050 Provaglio d'Iseo (BS), Italy, dr.tavormina.g
The relationship between the art forms of photography and poetry and mental wellbeing is described, both for the psychiatrist and for the patient. These, as well as other art forms, improve the experience of human persons interior life. It is suggested that these art forms, as well as music and dance, can be helpful in the treatment of Depression. Read More
Dig Endosc 2018 Nov 12. Epub 2018 Nov 12.
Division of Gastroenterolgy, Showa University, Fujigaoka Hospital Fujigaoka1-30, Aoba-ku, Yokohama, 227-8501, Japan.
Background: Peroral endoscopic myotomy (POEM) for achalasia is technically more challenging to perform in patients with type III, multiple prior treatments, prior myotomy, and sigmoid-type. Here we present a series of consecutive patients with complex achalasia and introduce the POEM Difficulty Score (PDS).
Aim: To demonstrate the application and discuss the utility of the PDS, and present the feasibility, safety, and efficacy of POEM in complex achalasia patients. Read More
J Homosex 2018 Nov 8:1-17. Epub 2018 Nov 8.
a Singapore American School , Princeton University , Singapore , Singapore.
This qualitative study explores identity formation in LGBT+ Singaporean adolescents, and how reading, writing, and listening to poetry shapes Singaporean adolescents' social identities as queer people. Analyzing in-depth interviews with nine LGBT+ Singaporean adolescents, four themes were found: (1) LGBT+ Singaporean adolescents interested in poetry believe that reading, writing, and/or listening to poetry has been an integral part of constructing their queer identities; (2) the poems that have impacted LGBT+ Singaporean adolescents' queer identities the most have been informed by queer sociocultural values; (3) poetry provides validation to LGBT+ Singaporean adolescents that their identities are real and that others before them have experienced the same challenges they are going through; and (4) poetry serves as a third space for LGBT+ Singaporean adolescents to safely construct their growing queer identities. Implications for teachers, counselors, and adult supporters of queer Singaporean adolescents are discussed, and recommendations for future research are provided. Read More
Leuk Lymphoma 2018 Nov 8:1-5. Epub 2018 Nov 8.
b Department of Hematology , Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , People's Republic of China.
Hypothyroidism is the most common endocrine disorder in POEMS syndrome. In this single-center prospective study, 36 patients with newly diagnosed POEMS syndrome were treated with lenalidomide (10 mg daily for 21 days) and dexamethasone (40mg once per week) for 12 cycles. Hypothyroidism was demonstrated in 58. Read More
PLoS One 2018 7;13(11):e0205980. Epub 2018 Nov 7.
Department of Language and Literature, Max Planck Institute for Empirical Aesthetics, Frankfurt, Germany.
Research on the music-language interface has extensively investigated similarities and differences of poetic and musical meter, but largely disregarded melody. Using a measure of melodic structure in music--autocorrelations of sound sequences consisting of discrete pitch and duration values--, we show that individual poems feature distinct and text-driven pitch and duration contours, just like songs and other pieces of music. We conceptualize these recurrent melodic contours as an additional, hitherto unnoticed dimension of parallelistic patterning. Read More
Br J Haematol 2018 Oct 29. Epub 2018 Oct 29.
MRC Centre for Neuromuscular Disease, National Hospital of Neurology and Neurosurgery and Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.
J Natl Cancer Inst 2018 Oct 27. Epub 2018 Oct 27.
Seattle Cancer Care Alliance, Fred Hutchinson Cancer Research Center, Department of Medicine, University of Washington, Seattle, WA.
J Natl Cancer Inst 2018 Oct 27. Epub 2018 Oct 27.
Loyola University Medical Center, Cardinal Bernardin Cancer Center, Maywood, IL.
Premature menopause is a serious long-term side effect of chemotherapy. We evaluated long-term pregnancy and disease-related outcomes for patients in S0230/POEMS, a study in premenopausal women with stage I-IIIA estrogen receptor-negative, progesterone receptor-negative breast cancer to be treated with cyclophosphamide-containing chemotherapy. Women were randomly assigned to standard chemotherapy with or without goserelin, a gonadotropin-releasing hormone agonist, and were stratified by age and chemotherapy regimen. Read More
Am J Nurs 2018 Nov;118(11):33
Shanna Powlus Wheeler directs the Writing Center at Lycoming College in Williamsport, PA. Her chapbook of poems, Lo & Behold, was published by Finishing Line Press, and her first full-length book of poems, Evensong for Shadows, is forthcoming from Resource Publications, an imprint of Wipf and Stock Publishers. About this poem, Wheeler writes, "This poem is dedicated to my grandmother, a retired nurse, who in an unofficial, at-home capacity cared for me just after my first miscarriage-in the raw aftershock." "D&C Aftercare" © 2018 by Shanna Powlus Wheeler. Contact author:
J Hematol Oncol 2018 Oct 22;11(1):128. Epub 2018 Oct 22.
Department of Hematology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jie-Fang Avenue, Wuhan, 430030, Hubei, People's Republic of China.
Background: POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome still has no standard treatment. On the basis that both POEMS syndrome and myeloma have an underlying plasma cell dyscrasia, anti-myeloma therapy can be expected to be useful for POEMS syndrome. Chimeric antigen receptor T (CAR-T) cells targeting B cell maturation antigen (BCMA) has been used in the treatment of relapsed and refractory multiple myeloma (RRMM). Read More
J Wound Care 2018 Oct;27(10):659-661
Department of Internal Medicine, University Hospital of Heraklion, Crete, Greece.
Homer's epics, the Iliad and the Odyssey, written between 800-700 BC, offer valuable information about what medical practice meant at that time. Descriptions of injuries and care given can be found among the 26,000 verses of these poems. During the Trojan War many warriors possessed empirical knowledge of wound care. Read More
Onco Targets Ther 2018 27;11:6271-6276. Epub 2018 Sep 27.
Department of Hematology, University Emergency Hospital Bucharest, Bucharest, Romania,
POEMS syndrome (acronym consisting of: polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) is an uncommon disorder associated with an underlying plasma cell dyscrasia. There is no single specific test for POEMS, and due to its rarity and heterogeneity, patients are often mis- or underdiagnosed. Castleman disease (CD) is a rare lymphoproliferative disorder, closely related to POEMS syndrome; ~11%-30% of POEMS patients are associated with concomitant CD. Read More
BMC Neurol 2018 Oct 9;18(1):169. Epub 2018 Oct 9.
Oncology Department, the 1st Affiliated Hospital of Anhui Medical University, Jixi Road 218, Hefei, 230022, China.
Background: POEMS syndrome is a rare neoplastic syndrome reflected by plasma cell disorder. It is composed by polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes. It is also reported to associate with Castleman disease. Read More
J Intellect Disabil 2018 Oct 9:1744629518805603. Epub 2018 Oct 9.
Ulster University, Ireland.
The transformational role education plays in the lives of people with intellectual disabilities has not been fully examined. The purpose of this study was to explore and investigate the meanings people with intellectual disabilities construct of their experiences in post-secondary and higher education. Heideggerian hermeneutic phenomenology was the qualitative methodology adopted for the study. Read More
Front Psychol 2018 21;9:1781. Epub 2018 Sep 21.
Faculty in Sopot, SWPS University of Social Sciences and Humanities, Sopot, Poland.
Poetry is one of the most creative uses of language. Yet the influence of poetry on creativity has received little attention. The present research aimed to determine how the reception of different types of poetry affect creativity levels. Read More
J Neurol Neurosurg Psychiatry 2018 Oct 2. Epub 2018 Oct 2.
Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan
Objective: To propose the optimal diagnostic criteria for polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes (POEMS) syndrome using appropriate statistical methods and disease controls.
Methods: This retrospective cohort study included 104 consecutive patients with suspected POEMS syndrome, among whom a gold standard group of 60 patients with definitive POEMS syndrome diagnosis were followed for at least 12 months to strictly exclude other disorders mimicking POEMS syndrome and to confirm response to POEMS syndrome-specific treatment. Thirty patients with chronic inflammatory demyelinating polyradiculoneuropathy (demyelinating polyradiculoneuropathy controls) and 30 with multiple myeloma or immunoglobulin light chain amyloidosis (monoclonal plasma cell proliferation controls) were also included. Read More
Clin Neuropharmacol 2018 Nov/Dec;41(6):232-235
Department of Neurology and Stroke Center, La Paz University Hospital, Autonomous University of Madrid, La Paz University Hospital Health Research Institute (IdiPAZ), Madrid, Spain.
Objective: The aim of the study was to illustrate the increased risk of ischemic stroke in the context of multiple myeloma (MM) under treatment with lenalidomide combined with dexamethasone.
Methods: This is a case report and literature review.
Results: A 62-year-old woman diagnosed with relapsed MM under treatment with lenalidomide and dexamethasone presented with acute onset disorientation, disturbed behavior, and aphasia. Read More
J Poet Ther 2018 13;31(2):107-112. Epub 2018 Mar 13.
Duke University, Center for the Study of Aging and Human Development, PO Box 3003 DUMC, Durham, NC 27710, 919-660-7750, Durham Veterans Administration Medical Center, 508 Fulton St., Mailstop GRECC 182, Durham, NC 27705, 919-286-0411 x 6098.
In this brief report three poems stemming from previously completed research into the motivations of 12 Black women who participate in triathlons, are presented. A review of the transcripts revealed impactful stories from the previously identified themes Competition, Triathlete Lifestyle, and Lifespan Participation. A phenomenological approach to this post-hoc qualitative analysis provides an outlet for poetic expression. Read More
J Neurol 2018 Sep 27. Epub 2018 Sep 27.
Neuropathology Unit, Division of Neuroscience and Department of Neurology, Institute of Experimental Neurology, San Raffaele Scientific Institute, Via Olgettina 48, 20132, Milan, Italy.
POEMS syndrome is a rare, chronic, disabling paraneoplastic disorder characterized by peripheral neuropathy, organomegaly, endocrinopathy, monoclonal plasma cells disorder and skin changes. Diagnosis relies on the fulfillment of a set of clinical criteria of which polyneuropathy and a monoclonal plasma cell dyscrasia are early and essential features. Treatment may be either local or systemic and is aimed at the monoclonal plasma cell disorder. Read More
J Clin Endocrinol Metab 2018 Sep 17. Epub 2018 Sep 17.
Department of Endocrinology, University College London Hospitals NHS Foundation Trust, London, UK.
Context: POEMS syndrome is a rare multisystem disorder characterised by polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma-proliferative disorder and skin changes among other features.
Objective: To describe the prevalence and course of the endocrine dysfunction in the context of POEMS.
Design: Cohort study with systematic review of the endocrinopathy in POEMS. Read More
Am Fam Physician 2018 Jul;98(2):93-98
College of Public Health, University of Georgia, Athens, GA, USA.
This article discusses the POEMs (patient-oriented evidence that matters) of 2017 judged to be most consistent with the principles of the Choosing Wisely campaign. A POEM is a synopsis of a research study that reports patient-oriented outcomes, such as improvement in symptoms, quality of life, or mortality; is free of important methodologic bias; and recommends a change in practice for many physicians. We selected these POEMs through a crowdsourcing strategy of the daily POEMs information service for physician-members of the Canadian Medical Association. Read More
Mediterr J Hematol Infect Dis 2018 1;10(1):e2018057. Epub 2018 Sep 1.
Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia. UOC Neurologia.
Peripheral neuropathies are a vast group of diseases with heterogeneous aetiologies, including genetic and acquired causes. Several haematological disorders may cause an impairment of the peripheral nervous system, with diverse mechanisms and variable clinical, electrophysiological and pathological manifestations. In this practical review, we considered the main phenotypes of peripheral nervous system diseases associated with lymphoproliferative disorders. Read More
Iran J Neurol 2018 Apr;17(2):95-96
Department of Neurology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Can Fam Physician 2018 Sep;64(9):e387-e393
Master's degree candidate at the University of London.
Objective: To explore the experience of family and close friends of patients seeking medical assistance in dying (MAID) in Canada.
Design: Qualitative study using semistructured interviews.
Setting: A clinic in Vancouver, BC, that provides MAID services. Read More
Ann Fam Med 2018 Sep;16(5):436-439
Department of Family Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio.
POEMs (patient-oriented evidence that matters) are studies that address a relevant clinical question, demonstrate improved patient-oriented outcomes, and have the potential to change practice. For 20 years the authors of this article have reviewed more than 100 English language clinical journals monthly to identify POEMs in the medical literature relevant to primary care practice. This article identifies the POEMs in each of the last 20 years that were highest ranked for having recommended a major and persistent change in practice that year. Read More
Hematol Oncol 2018 Sep 7. Epub 2018 Sep 7.
Division of Hematology, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy.
The finding of an IgM monoclonal gammopathy often represents a diagnostic challenge. In fact, there are many pathological disorders associated with this condition, each of which has distinctive characteristics and requires specific clinical, instrumental, and laboratory assessments to set the appropriate treatment. This review has two aims. Read More
Neurol Neuroimmunol Neuroinflamm 2018 Sep 15;5(5):e486. Epub 2018 Aug 15.
MRC Centre for Neuromuscular Diseases (M.P., S.K., M.M.R., M.P.L.), National Hospital for Neurology and Neurosurgery, Queen Square, London, UK; Cancer Division (S.D., K.L.Y.), University College London Hospitals NHS Foundation Trust, London, UK; and Department of Neuroimmunology (A.J.C., M.P.L.), Institute of Neurology, Queen Square, London, UK.
Objective: To investigate the sensitivity and the specificity of serum vascular endothelial growth factor (sVEGF) for the diagnosis of polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS) syndrome in patients with a neuropathy (NP) and to identify confounding causes of raised vascular endothelial growth factor (VEGF) in this context to improve accuracy.
Methods: We studied the specificity and sensitivity of sVEGF for the diagnosis of POEMS syndrome in a cohort of 195 consecutive patients with an NP in serum samples from June 2009 to November 2013, including 27 untreated patients with POEMS syndrome. We then studied VEGF in other neuropathies and analyzed causes of elevated VEGF in a multiple logistic regression analysis in a larger cohort of 236 patients including 168 with a non-POEMS NP and 68 without NP. Read More
Arch Med Sci 2018 Aug 2;14(5):1048-1054. Epub 2016 Nov 2.
Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Introduction: Lenalidomide is an effective therapy of POEMS syndrome. However, there is concern that exposure to lenalidomide may reduce the efficiency of blood cell collection in persons who may eventually receive an autotransplant. We studied the impact of lenalidomide therapy on subsequent blood cell mobilization and collection including frequency of blood CD34+ cells and CXCR4 expression before and after mobilization with cyclophosphamide and granulocyte-colony stimulating factor (G-CSF). Read More
Curr Opin Neurol 2018 Oct;31(5):551-558
Centre for Neuromuscular Disease, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom.
Purpose Of Review: To provide an overview of polyneuropathy organomegaly endocrinopathy M-protein and skin changes (POEMS) syndrome, detailing new insights into pathogenesis, prognostic factors, treatments, and outcome scores.
Recent Findings: With the development of large multicentre national cohorts of patients, POEMS syndrome is evolving into a well characterized multisystem hematoneurological syndrome. Without early diagnosis significant disability results from the neuropathy. Read More
Zhongguo Shi Yan Xue Ye Xue Za Zhi 2018 Aug;26(4):1225-1229
Department of Hematology, Center for Hematologic Diseases of Chinese PLA, Lanzhou Military Command General Hospital, Lanzhou 730050, Gansu Proince, China.E-mail:
POEMS syndrome is a rare multiple organ involvement of the parasympathetic syndrome associated with abnormal plasma cells, mostly with high-dose chemotherapy and stem cell transplantation for the treatment. Recently, more treatment attempts to treat POEMS syndrome have been utilized so as to improve the efficacy and safety for the patients with POEMS syndrome, such as immunomodulator, alkylating agent, cytokine-induced killer cells and so on. Lenalidomide has a significant effect on relapse/refractory POEMS syndrome and patients with endocrinopathy. Read More
Front Psychol 2018 25;9:1284. Epub 2018 Jul 25.
Language and Literature, Max-Planck-Institut für empirische Ästhetik, Frankfurt, Germany.
Conveying emotions in spoken poetry may be based on a poem's semantic content and/or on emotional prosody, i.e., on acoustic features above single speech sounds. Read More
Pathology 2018 Oct 3;50(6):674-676. Epub 2018 Aug 3.
Department of Clinical Immunology and Allergy, Royal North Shore Hospital, Sydney, NSW, Australia; Immunorheumatology Laboratory, New South Wales Health Pathology, Sydney, NSW, Australia; The University of Sydney, Sydney, NSW, Australia.
Surg Endosc 2018 Jul 27. Epub 2018 Jul 27.
Department of Surgery, Baystate Medical Center, University of Massachusetts Medical School, 759 Chestnut Street, Springfield, MA, 01199, USA.
Introduction: High-resolution esophageal manometry (HREM) is essential in characterizing achalasia subtype and the extent of affected segment to plan the myotomy starting point during per-oral endoscopic myotomy (POEM). However, evidence is lacking that efficacy is improved by tailoring myotomy to the length of the spastic segment on HREM. We sought to investigate whether utilizing HREM to dictate myotomy length in POEM impacts postoperative outcomes. Read More
BMJ Case Rep 2018 Jul 26;2018. Epub 2018 Jul 26.
Internal Medicine, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes (POEMS) syndrome is a rare systemic disease, often unrecognised in the primary care setting. POEMS syndrome is associated with plasma cell dyscrasias and upregulation of vascular endothelial growth factor leading to systemic oedema, papilloedema and pulmonary hypertension. A wide constellation of presenting symptoms often leads to late diagnosis. Read More
Leukemia 2018 Sep 23;32(9):1883-1898. Epub 2018 Jul 23.
Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
The introduction of novel agents in the management of multiple myeloma and related plasma cell dyscrasias has changed our treatment approaches and subsequently the outcome of patients. Due to current advances, the European Myeloma Network updated the diagnostic and therapeutic recommendations for patients with Waldenström's macroglobulinemia (WM), AL-amyloidosis, monoclonal immunoglobulin deposition disease (MIDD), POEMS syndrome, and primary plasma cell leukemia. For patients with WM, the combination of rituximab with chemotherapy remains the treatment cornerstone, while the Bruton-tyrosine kinase inhibitor ibrutinib has been introduced and approved for relapsed/refractory disease. Read More
Am J Hematol 2018 Sep 31;93(9):1161-1168. Epub 2018 Aug 31.
Department of Hematology, Chiba University Hospital, Chiba, Japan.
Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS) syndrome is a rare plasma cell dyscrasia characterized by polyneuropathy, organomegaly, endocrinopathy, extravascular fluid overload, M protein, and a myriad of skin changes. The pathogenesis is poorly understood, but monoclonal plasma cells are λ-restricted and these immunoglobulin λ light chain variable (IGLV) region genes are derived from only two germlines, either IGLV1-44 or 1-40. Here we analyzed the clonal IGLV gene rearrangements of genomic DNA samples of bone marrow mononuclear cells using next-generation sequencing (NGS) to understand the clonal composition of IGLV genes in patients with POEMS syndrome (n = 30). Read More
Perm J 2018 06;22
Poet and the cofacilitator of the Montreal Pain Support Group in Quebec, Canada.
This article explores the efficacy of writing and reading poetry as a means to help people living with chronic pain to explore and express their narratives in their own unique way. Throughout our narrative we have interwoven poems from Eugene Feig, one of the authors of this article. His poetry is sent out almost weekly to the members of our pain support group as a method of sharing his own experiences of living with pain, as well as to support and to inspire hope in others. Read More
Indian J Nucl Med 2018 Jul-Sep;33(3):224-226
Department of Nuclear Medicine, Basavatarakam Indo-American Cancer Hospital and Research Institute, Hyderabad, Telangana, India.
Castleman's disease (CD) is a rare benign lymphoproliferative disorder. We are presenting three cases of CD of which one is unicentric CD, and the other two are an idiopathic multicentric CD. One of the two multicentric cases is associated with POEMS syndrome. Read More
J Neurol Neurosurg Psychiatry 2018 Jun 26. Epub 2018 Jun 26.
Department of Medical Biotechnology and Translational Medicine, Milan University, Neuromuscular and Neuroimmunology Service, Humanitas Clinical and Research Center, Rozzano, Italy
Postgrad Med J 2018 Jun 19. Epub 2018 Jun 19.
Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Neurology 2018 Jul 15;91(2):e143-e152. Epub 2018 Jun 15.
From Service de Physiologie Clinique-Explorations Fonctionnelles (P.L.), AP-HP, Hôpital Lariboisière, Paris; INSERM UMR965 (P.L.), Paris; Université Paris Diderot Sorbonne Paris Cité (P.L., B.A.), Paris; French National Reference Center for FAP (NNERF) (L.-L.M., P.D., G.B., M.T., C.A., D.A.), Le Kremlin-Bicêtre; Service de Neurologie (L.-L.M., P.D., M.T., D.A.) and Service d'anatomopathologie (C.A.), APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre; Unité de Neurophysiologie Clinique et d'épileptologie (G.B.), Hôpital Bicêtre, Le Kremlin-Bicêtre; Immuno-Hematology Department (B.A.), Saint-Louis Hospital, Paris; Université Paris 11 (D.A.); and INSERM UMR1195 (D.A.), Le Kremlin-Bicêtre, France.
Objective: To clearly define transthyretin familial amyloid polyneuropathies (TTR-FAPs) fulfilling definite clinical and electrophysiologic European Federation of Neurological Societies/Peripheral Nerve Society criteria for chronic inflammatory demyelinating polyneuropathy (CIDP).
Methods: From a cohort of 194 patients with FAP, 13 of 84 patients (15%) of French ancestry had late-onset demyelinating TTR-FAP. We compared clinical presentation and electrophysiology to a cohort with CIDP and POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes) syndrome. Read More
J Cancer Res Ther 2018 Apr-Jun;14(3):679-681
Department of Internal Medicine, Health East Care System, Saint Paul, Minnesota, 55102, USA.
POEMS syndrome is a multisystem disorder characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. We present an atypical case of POEMS syndrome with subclinical polyneuropathy, splenomegaly, hypogonadism, and myeloma of immunoglobulin G kappa type. The typical osteosclerotic lesions and skin lesions were absent, and vascular endothelial growth factor (VEGF) level was normal. Read More
Rinsho Ketsueki 2018;59(5):489-491
Department of Hematology and Immunology, Kagoshima University Hospital.
POEMS syndrome is often complicated by pulmonary hypertension. The standard therapy for patients with POEMS syndrome is high-dose chemotherapy followed by autologous stem cell transplantation. However, the safety of high-dose chemotherapy for patients complicated with pulmonary hypertension remains unclear, and the optimal therapy for these patients is yet to be establishment. Read More
J Christ Nurs 2018 Jul/Sep;35(3):198
Sharon Fish Mooney, PhD, RN, has had poems published in First Things, The Evansville Review, Modern Age, RUMINATE and Christian Research Journal. She won the inaugural Frost Farm Prize for metrical poetry and is the author of Bending Toward Heaven - Poems After the Art of Vincent van Gogh (Wipf and Stock).
J Infect Chemother 2018 Dec 31;24(12):983-986. Epub 2018 May 31.
Department of Hematology, Tottori Prefectural Central Hospital, Tottori, Japan.
Although hematopoietic stem cell transplantation (HSCT) may increase the curability of refractory hematologic diseases, it requires complication management due to a long-term immunocompromised state. We experienced a case who received an autologous peripheral blood stem cell transplantation (Auto-PBSCT) for POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) and developed cutaneous Mycobacterium chelonae infection. It is clear that attention needs to be paid to prevent bacterial, fungal and viral infection after HSCT. Read More
Ann N Y Acad Sci 2018 May;1419(1):38-56
FSG Advisory Services, Inclusive Markets, Mumbai, Maharashtra, India.
FSG is a mission-driven nonprofit organization supporting leaders in creating large-scale, lasting social change. A survey conducted by FSG in 2015 across 4407 low-income families in urban India showed that 95% of them send their children to preschools, a majority of choosing affordable private preschools (APSs), as parents perceive the quality of government schools to be poor. Parents use and value rote-based methods (e. Read More
Am Fam Physician 2018 May;97(9):581-588
McGill University, Montreal, Quebec, Canada.
Based on systematic surveillance of more than 110 medical journals, 247 studies met criteria as POEMs (patient-oriented evidence that matters) in 2017. Members of the Canadian Medical Association identified 20 of these POEMs as most relevant to practice. This article reviews the clinical questions and bottom-line answers from these studies. Read More