34,764 results match your criteria Otitis Externa


Ossicular chain reconstruction in chronic otitis media: hearing results and analysis of prognostic factors.

Braz J Otorhinolaryngol 2018 Oct 18. Epub 2018 Oct 18.

Hospital Governador Celso Ramos, Departamento de Otorrinolaringologia, Florianópolis, SC, Brazil.

Introduction: The goal of ossiculoplasty is to improve hearing and the success of this procedure depends on several factors.

Objective: Analyze the hearing results in patients with chronic otitis media undergoing ossicular chain reconstruction, as well as predictive factors for successful surgery.

Methods: Charts of patients undergoing ossiculoplasty between 2006 and 2016 were reviewed. Read More

View Article
October 2018

The proportion, conditions, and predictors of emergency department visits that can be potentially managed by pharmacists with expanded scope of practice.

Res Social Adm Pharm 2018 Dec 7. Epub 2018 Dec 7.

School of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, N2G 1C5, ON, Canada; Ontario Pharmacy Evidence Network (OPEN), School of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, N2G 1C5, ON, Canada.

Background: Pharmacists have been shown to be beneficial for inclusion in emergency department (ED) services; however, little has been done to assess these benefits with pharmacists having even wider scopes of practice, including limited prescribing authority.

Objectives: The aims of this study were to determine the proportion of ED visits that can potentially be managed by pharmacists, the most prevalent conditions within these cases, and the factors associated with patients presenting with such cases to the ED.

Methods: This was a retrospective quantitative cohort study using administrative databases from 2010 to 2017. Read More

View Article
December 2018

Probiotics Streptococcus salivarius 24SMB and Streptococcus oralis 89a interfere with biofilm formation of pathogens of the upper respiratory tract.

BMC Infect Dis 2018 Dec 13;18(1):653. Epub 2018 Dec 13.

Laboratory of Clinical Chemistry and Microbiology, IRCCS Orthopedic Institute Galeazzi, Milan, Italy.

Background: Infections of the ears, paranasal sinuses, nose and throat are very common and represent a serious issue for the healthcare system. Bacterial biofilms have been linked to upper respiratory tract infections and antibiotic resistance, raising serious concerns regarding the therapeutic management of such infections. In this context, novel strategies able to fight biofilms may be therapeutically beneficial and offer a valid alternative to conventional antimicrobials. Read More

View Article
December 2018

Differences in Antibiotic Resistance of MRSA Infections in Patients with Various Types of Otitis Media.

J Int Adv Otol 2018 Dec 12. Epub 2018 Dec 12.

Department of Otorhinolaryngology, Head and Neck Surgery, Kyung Hee University, Seoul, Korea.

Objectives: We investigated the epidemiological and antibiotic resistance differences in methicillin-resistant Staphylococcus aureus (MRSA) infections in patients with otitis media with effusion (OME), acute otitis media (AOM), chronic suppurative otitis media (CSOM), and chronic cholesteatomatous otitis media (CCOM).

Materials And Methods: We conducted a retrospective study of patients with newly identified MRSA infections from January 2009 through January 2017. Overall, 3,522 patients from 10 tertiary referral hospitals were included in the study. Read More

View Article
December 2018

Auditory and Histopathological Effects of Topical Mercurochrome Treatment in Rats with Tympanic Membrane Perforation.

J Int Adv Otol 2018 Dec 12. Epub 2018 Dec 12.

Department of Otorhinolaryngology, Health Sciences University, İzmir Bozyaka Training and Research Hospital, İzmir, Turkey.

Objectives: Topical treatment is first choice in the treatment of uncomplicated chronic otitis media. It was intended to assess auditory and histopathological safety of ototopical use of mercurochrome solution in rats with induced tympanic membrane perforation.

Materials And Methods: The study was conducted on 21 female Wistar-Albino rats which were randomly assigned into 3 groups. Read More

View Article
December 2018

The Association between Iron Deficiency and Otitis Media with Effusion.

J Int Adv Otol 2018 Dec 12. Epub 2018 Dec 12.

Department of Otorhinolaryngology, Düzce University School of Medicine, Düzce, Turkey.

Objectives: The purpose of this trial is to examine the clinical role of iron metabolism on development of Otitis media with effusion.

Materials Methods: This prospective study was conducted in a tertiary referral center. The study group made up of children who had surgery for Otitis media with effusion (OME). Read More

View Article
December 2018

A Novel 12q13.2-q13.3 Microdeletion Syndrome With Combined Features of Diamond Blackfan Anemia, Pierre Robin Sequence and Klippel Feil Deformity.

Front Genet 2018 19;9:549. Epub 2018 Nov 19.

Department of Woman, Child and General and Specialized Surgery, University of Campania "L. Vanvitelli" Naples, Italy.

Diamond-Blackfan anemia (DBA) is a rare congenital erythroid aplasia with a highly heterogeneous genetic background; it usually occurs in infancy. Approximately 30-40% of patients have other associated congenital anomalies; in particular, facial anomalies, such as cleft palate, are part of about 10% of the DBA clinical presentations. Pierre Robin sequence (PRS) is a heterogeneous condition, defined by the presence of the triad of glossoptosis, micrognathia and cleft palate; it occurs in 1/8500 to 1/14,000 births. Read More

View Article
November 2018

Antimicrobial susceptibility patterns of bacteria isolated from patients with ear discharge in Jimma Town, Southwest, Ethiopia.

BMC Ear Nose Throat Disord 2018 4;18:17. Epub 2018 Dec 4.

1School of Medical Laboratory Sciences, Institute of Health, Jimma University, P.O. Box 378, Jimma, Ethiopia.

Background: Otitis media is among the leading causes of childhood illnesses although it can also affect the adults resulting in frequent physician visits, drug prescription and a key contributor to antibiotic resistance. The aim of this study was to determine the risk factors, bacterial profile, and the antimicrobial susceptibility pattern of the isolates from patients with discharging ears which clinically equates to draining otitis media in developing countries with limited medical resources such as otoscope.

Methods: A prospective cross-sectional study was conducted on 173 patients with draining otitis media. Read More

View Article
December 2018

Surgery for Chronic Otitis Media Causes Greater Taste Disturbance Than Surgery for Otosclerosis.

Otol Neurotol 2019 Jan;40(1):e32-e39

Department of Otorhinolaryngology.

Objectives: Patients with otosclerosis more often complain about postoperative taste disturbance than patients with chronic otitis media, which seems paradoxical. We aim to investigate if and potentially why this seems to be the case, since the chorda tympani nerve (CTN) is thought to be severely traumatized less frequently during surgery in the former than in the latter.

Study Design: Prospective cohort study. Read More

View Article
January 2019

Cost-Effectiveness of the Pneumococcal Conjugate Vaccine (10- or 13-Valent) Versus No Vaccination for a National Immunization Program in Tunisia or Algeria.

Infect Dis Ther 2018 Dec 11. Epub 2018 Dec 11.

Pfizer, Collegeville, PA, USA.

Introduction: To evaluate the expected impact of the Algeria national immunization program (NIP) and potential impact for a Tunisia NIP, this study assessed the public health and economic value of vaccination, through a cost-effectiveness analysis, for a PCV13 or PCV10 NIP, compared with no vaccination.

Methods: A decision-analytic model was programmed in Microsoft Excel™ and adapted to evaluate the clinical and economic outcomes of PCV vaccination. Assuming a steady state, the model estimated invasive pneumococcal disease (IPD; bacteremia and meningitis), all-cause pneumonia (inpatient and outpatient), and all-cause otitis media cases as well as the associated costs from a payer perspective. Read More

View Article
December 2018

Antibodies against the Majority Subunit (PilA) of the Type IV Pilus of Nontypeable Haemophilus influenzae Disperse Moraxella catarrhalis from a Dual-Species Biofilm.

MBio 2018 Dec 11;9(6). Epub 2018 Dec 11.

Center for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA

Otitis media (OM) is often polymicrobial, with nontypeable (NTHI) and (Mcat) frequently cocultured from clinical specimens. Bacterial biofilms in the middle ear contribute to the chronicity and recurrence of OM; therefore, strategies to disrupt biofilms are needed. We have focused our vaccine development efforts on the majority subunit of NTHI type IV pili, PilA. Read More

View Article
December 2018

Otopathology in Angiosarcoma of the Temporal Bone.

Laryngoscope 2018 Dec 11. Epub 2018 Dec 11.

Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts.

Objectives/hypothesis: Investigate the otopathology of angiosarcoma of the temporal bone, which has not been previously described in the literature.

Study Design: Postmortem evaluation and literature review.

Methods: Postmortem histological evaluation of the temporal bones and review of the literature for the treatment and prognosis of this rare disease were performed. Read More

View Article
December 2018
4 Reads

Closed Complete Genome Sequences of Two Nontypeable Haemophilus influenzae Strains Containing Novel Alleles from the Sputum of Patients with Chronic Obstructive Pulmonary Disease.

Microbiol Resour Announc 2018 Jul 19;7(2). Epub 2018 Jul 19.

Institute for Glycomics, Griffith University, Gold Coast, Queensland, Australia.

Nontypeable Haemophilus influenzae (NTHi) is an important bacterial pathogen that causes otitis media and exacerbations of chronic obstructive pulmonary disease (COPD). Here, we report the complete genome sequences of NTHi strains 10P129H1 and 84P36H1, isolated from COPD patients, which contain the phase-variable epigenetic regulators ModA15 and ModA18, respectively. Read More

View Article

Allergic bronchopulmonary aspergillosis successfully treated with mepolizumab: Case report and review of the literature.

Respir Med Case Rep 2019 24;26:59-62. Epub 2018 Nov 24.

Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan.

A 56-year-old woman was referred to our hospital for recurrent asthma of 20 years duration. She was diagnosed as having allergic bronchopulmonary aspergillosis on the basis of clinical symptoms, peripheral blood eosinophilia, elevated total serum immunoglobulin E value, positive results of specific IgE and precipitating antibodies against sp., central bronchiectasis, and mucoid impaction. Read More

View Article
November 2018

The Value of Diffusion-Weighted MRI in the Long-term follow-up After Subtotal Petrosectomy for Extensive Cholesteatoma and Chronic Suppurative Otitis Media.

Otol Neurotol 2019 Jan;40(1):e25-e31

European Institute for Otorhinolaryngology-Head and Neck Surgery.

Objective: To report the long-term follow-up with diffusion-weighted magnetic resonance imaging (DW MRI) after subtotal petrosectomy (SP) with blind sac closure of the external auditory canal for extensive cholesteatoma and chronic suppurative otitis media.

Study Design: Retrospective clinical record study.

Setting: Tertiary referral center. Read More

View Article
January 2019

Staphylococcus aureus from ocular and otolaryngology infections are frequently resistant to clinically important antibiotics and are associated with lineages of community and hospital origins.

PLoS One 2018 6;13(12):e0208518. Epub 2018 Dec 6.

Infectious Diseases Institute, Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States of America.

Staphylococcus aureus is an important human pathogen that causes serious antibiotic-resistant infections. Its population structure is marked by the appearance and dissemination of successful lineages across different settings. To begin understanding the population structure of S. Read More

View Article
December 2018
2 Reads

Decreased Aquaporin 4 and 6 mRNAs in Patients With Chronic Otitis Media With Otorrhea.

Clin Exp Otorhinolaryngol 2018 Dec 7. Epub 2018 Dec 7.

Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University, Seoul, Korea.

Objectives: Aquaporins (AQPs) are integral membrane proteins engaged in the modulation of water homeostasis, but the roles they play in chronic otitis media (COM) have not been well investigated. Accordingly, we undertook document relations between the mRNA expressions of AQPs and COM, and explored the relation between these expressions and otorrhea, which is one of the most common symptoms of COM.

Methods: Levels of the mRNAs of AQP 1, 2, 3, 4, 5, 6, 8, and 10 were assayed by real-time polymerase chain reaction in inflammatory tissue samples from 81 patients with COM with or without otorrhea. Read More

View Article
December 2018
1 Read

Oral steroids for persistent otitis media with effusion.

Authors:
David Isaacs

J Paediatr Child Health 2018 Dec;54(12):1399-1400

Children's Hospital at Westmead, Sydney.

View Article
December 2018
1 Read

Additive value of Technetium methylene diphosphonate hybrid single-photon emission computed tomography/computed tomography in the diagnosis of skull base osteomyelitis in otitis externa patients compared to planar bone scintigraphy.

World J Nucl Med 2018 Oct-Dec;17(4):286-292

Department of Oncology and Nuclear Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.

The aim of this study was to evaluate the additive value of technetium methylene diphosphonate (Tc-MDP) hybrid single-photon emission computed tomography/computed tomography (SPECT-CT) in the diagnosis of skull base osteomyelitis (SBO) compared to planar bone scintigraphy (PBS). This was a single institution; prospective study included 23 patients with otitis externa, clinically suspected of SBO, all of them were diabetic. Three-phase bone scintigraphy and SPECT/CT were performed to all patients. Read More

View Article
December 2018
1 Read

Cefixime-associated acute generalized exanthematous pustulosis: Rare cases in India.

Indian J Pharmacol 2018 Jul-Aug;50(4):204-207

Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: Cefixime is a widely used third-generation cephalosporin schedule H1 drug, which is prescribed for the treatment of otitis media, respiratory tract infections, and uncomplicated urinary tract infections and is effective against infections caused by and species in India. The National Coordination Centre (NCC)-Pharmacovigilance Programme of India (PvPI), Indian Pharmacopoeia Commission (IPC), has received rare individual case safety reports (ICSRs) for acute generalized exanthematous pustulosis (AGEP) associated with the use of cefixime.

Materials And Methods: IPC, NCC-PvPI also acts as a national collaborating center for pharmacovigilance activities under the aegis of Ministry of Health and Family Welfare, Government of India; moreover, it is a member country in global pharmacovigilance system, World Health Organization-Uppsala Monitoring Centre, Sweden. Read More

View Article
December 2018
1 Read
0.679 Impact Factor

Cofactors of Pediatric Tinnitus: A Look at the Whole Picture.

Clin Pediatr (Phila) 2018 Dec 3:9922818816426. Epub 2018 Dec 3.

6 Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Retrospective chart review of 248 children (1-19 years old) with tinnitus who presented to a tertiary pediatric hospital between 2006 and 2011, looking at which cofactors are predictors of pediatric tinnitus. In our review, we extracted demographics, symptoms, historical data, imaging, and laboratory results; we compared with the general population. Eighty-seven percent had normal hearing. Read More

View Article
December 2018
1 Read

Etiology of Childhood Otorrhea in Luanda, Angola, and a Review of Otitis Media in African Children.

Pediatr Infect Dis J 2018 Dec 3. Epub 2018 Dec 3.

Children's Hospital, Helsinki University Hospital, Helsinki, Finland and University of Helsinki, Helsinki, Finland.

Background: In resource-poor settings, otorrhea causes a significant burden of disease in children. Etiologic studies and structured data on otorrhea and chronic otitis media among African children remain scarce.

Methods: Here, we reviewed 678 bacteriologically analyzed otorrhea samples from Luanda Children's Hospital from children ≤15 years of age between 2008 and 2015. Read More

View Article
December 2018
3 Reads

Actinomycosis of the Middle Ear and Mastoid.

Med Arch 2018 Oct;72(4):295-296

Saudi Board of Otorhinolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, King Fahad General Hospital -ALMusaedeah Center, Jeddah-Saudi Arabia.

Introduction: Actinomycosis is a saprophytic infection caused by actinomycetes. Actinomycetes is a gram positive, anaerobic, non acid-fast, filamentous bacterium. Although actinomyce is considered as a part of the normal flora, it is rarely seen in middle ear and mastoid cavity. Read More

View Article
October 2018
1 Read

Nasal balloon autoinflation for glue ear in primary care: a qualitative interview study.

Br J Gen Pract 2018 Dec 3. Epub 2018 Dec 3.

Primary Care and Population Sciences, University of Southampton, Southampton.

Background: Nasal balloon autoinflation is an effective, non-surgical treatment for symptomatic children with glue ear, although uptake is variable and evidence about acceptability and feasibility is limited.

Aim: To explore parent and healthcare professional views and experiences of nasal balloon autoinflation for children with glue ear in primary care.

Design And Setting: Qualitative study using semi-structured interviews with a maximum-variety sample of parents, GPs, and practice nurses. Read More

View Article
December 2018
3 Reads

Studying PCV impact on clinical presentation of otitis media helps to understand its pathogenesis.

Vaccine 2019 Jan 26;37(1):1-6. Epub 2018 Nov 26.

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. Electronic address:

Background: Complex otitis media (OM) may present with intact tympanic membrane or spontaneous otorrhea. We compared dynamics of intact tympanic membrane and spontaneous otorrhea OM following 7- and 13-valent conjugated vaccines (PCV7, PCV13) implementation, since differences in dynamics may imply different underlying mechanisms.

Methods: A prospective, population-based, active surveillance. Read More

View Article
January 2019
3 Reads

A Case Series of Granulomatosis With Polyangiitis Primarily Diagnosed by Otological Manifestations.

Ann Otol Rhinol Laryngol 2018 Nov 28:3489418815517. Epub 2018 Nov 28.

1 Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA, USA.

Objective:: To describe a case series of previously undiagnosed granulomatosis with polyangiitis (GPA) patients who presented primarily with otological manifestations.

Method:: We report a series of patients visited at a neurotology clinic who were eventually diagnosed with GPA based on their otologic complaints and had no prior knowledge of having this condition.

Results:: In this series, 10 (91%) patients presented with hearing loss (HL), more than half of which were bilateral (60%). Read More

View Article
November 2018
2 Reads

Cartilage tympanoplasty combined with eustachian tube balloon dilatation in the treatment of adhesive otitis media.

Laryngoscope 2018 Nov 28. Epub 2018 Nov 28.

Department of Otolaryngology-Head and Neck Surgery , Sun Yat-Sen Memorial Hospital, and Institute of Hearing and Speech-Language Science, Sun Yat-sen University, Guangzhou, China.

Objectives/hypothesis: To investigate the simultaneous application of cartilage tympanoplasty combined with eustachian tube (ET) balloon dilatation in the treatment of adhesive otitis media (AdOM).

Study Design: Multicenter, prospective, double-blind, randomized, controlled clinical trial.

Methods: Patients with AdOM were randomly divided into four groups: control group (conservative treatment), ET balloon dilatation (ETBD) group, cartilage tympanoplasty (CT) group, and cartilage tympanoplasty combined with ET balloon dilatation (ETBD+CT) group. Read More

View Article
November 2018
1 Read

Incidence and risk factors of new-onset hypertrophic pachymeningitis in patients with anti-neutrophil antibody-associated vasculitis: using logistic regression and classification tree analysis.

Clin Rheumatol 2018 Nov 27. Epub 2018 Nov 27.

Department of Nephrology Center, Toranomon Hospital, 2-2-2, Toranomon, Minatoku, 105-8470, Japan.

Objectives: Hypertrophic pachymeningitis (HP) is a rare complication in patients with anti-neutrophil antibody-associated vasculitis (AAV); its clinical features, incidence, and risk factors remain unknown. We aimed to clarify the prevalence, clinical features, and factors associated with new-onset HP in patients with AAV.

Method: A retrospective cohort study involving 93 patients with AAV was conducted. Read More

View Article
November 2018
1 Read

Isolation of multidrug-resistant Haemophilus influenzae harbouring multiple exogenous genes from a patient diagnosed with acute sinusitis.

J Infect Chemother 2018 Oct 25. Epub 2018 Oct 25.

Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Japan. Electronic address:

In paediatric patients, β-lactams and macrolides are widely used to treat acute otitis media and sinusitis, which are often caused by either Streptococcus pneumoniae or Haemophilus influenzae. However, resistant isolates have emerged and are becoming more prevalent. H. Read More

View Article
October 2018
1 Read

Clinical outcome of revision cartilage tympanoplasty.

Ear Nose Throat J 2018 Oct-Nov;97(10-11):349-361

Department of Otorhinolaryngology-Head and Neck Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.

We retrospectively reviewed 32 ears from 30 adult patients with chronic otitis media who underwent revision tympanoplasty using cartilage graft (performed by a single surgeon) from January 10, 2011, to May 10, 2016. All procedures were performed using an endaural incision for both temporalis fascia graft and tragal cartilage graft harvesting. The overall surgical success rate was 93. Read More

View Article
November 2018
5 Reads

Tympanometric Patterns of Children with Allergic Rhinitis Treated at a Tertiary Health Institution.

OTO Open 2017 Oct-Dec;1(4):2473974X17742648. Epub 2017 Nov 14.

Department of Otorhinolaryngology, University College Hospital and College of Medicine, University of Ibadan, Ibadan, Nigeria.

Objectives: To determine the prevalence of otitis media with effusion (OME) and compare patterns of tympanogram between children with and without allergic rhinitis in Ibadan, Nigeria.

Study Design: A case-control study of children (2-7 years) with AR from May 2015 to March 2016.

Setting: Tertiary hospital. Read More

View Article
November 2017
1 Read

Comment to Empirical Therapy for Chronic Suppurative Otitis Media.

Clin Med Insights Ear Nose Throat 2018 4;11:1179550618810226. Epub 2018 Nov 4.

Medical Graduate, Liaquat National Hospital & Medical College, Karachi, Pakistan.

Chronic suppurative otitis media is an inflammatory condition characterized by disruption of tympanic membrane and aural discharge. It is one of the most incidental conditions in head and neck. There has been a substantial debate about the therapeutic approach for some decades now. Read More

View Article
November 2018

Clinical Utility of Intraoperative Tympanomastoidectomy Assessment Using a Surgical Microscope Integrated with an Optical Coherence Tomography.

Sci Rep 2018 Nov 27;8(1):17432. Epub 2018 Nov 27.

School of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu, 41566, Republic of Korea.

Significant technical and optical advances are required for intraoperative optical coherence tomography (OCT) to be utilized during otological surgeries. Integrating OCT with surgical microscopy makes it possible to evaluate soft tissue in real-time and at a high resolution. Herein, we describe an augmented-reality, intraoperative OCT/microscope system with an extended working distance of 280 mm, providing more space for surgical manipulation than conventional techniques. Read More

View Article
November 2018
3 Reads

Inflammation of the Temporal Bone.

Neuroimaging Clin N Am 2019 Feb 29;29(1):1-17. Epub 2018 Oct 29.

Department of Radiology, University Hospitals of Leicester, Leicester University, Infirmary Square, Leicester LE1 5WW, UK.

Temporal bone and ear structure inflammation is commonly due to infection. It can be associated with a variety of complications and postinflammatory sequelae. Where the ear is easily inspected, clinical evaluation suffices. Read More

View Article
February 2019
5 Reads

Congenital Cholesteatoma in Adults-Interesting Presentations and Management.

Indian J Otolaryngol Head Neck Surg 2018 Dec 13;70(4):578-582. Epub 2018 Apr 13.

Christian Medical College, Vellore, 632004 India.

To report a series of adult patients diagnosed with congenital cholesteatoma (CC) with respect to symptoms, different varieties of presentation, surgical findings and approach used, complications and the postoperative results. A retrospective chart review of adult cases of CC who were treated in the period from January 2014-2017 was carried out in a tertiary care center. Levenson's criteria were used for diagnosis. Read More

View Article
December 2018
3 Reads

The Role of Surgical Debridement in Cases of Refractory Malignant Otitis Externa.

Indian J Otolaryngol Head Neck Surg 2018 Dec 18;70(4):549-554. Epub 2018 Jun 18.

Sri Guru Ram Das Institute of Health Sciences and Research Amritsar, 27-C; Sant Avenue, The Mall, Amritsar, 143001 India.

Malignant Otitis externa is a necrotizing condition of external ear involving causing the osteomyelitis of the bone and surrounding soft tissue leading to multiple cranial nerve palsies. Though most patients respond to oral ciprofloxacin but due to emerging resistance cases of refractory malignant otitis externa which are unresponsive to antibiotic therapy for at least 6 weeks are being encountered lately. A study of 20 patients of refractory malignant otitis Externa was conducted at a tertiary care centre in north India; 10 patients were randomly allotted in group A and group B each. Read More

View Article
December 2018
3 Reads

Aural Polyp is not Always Due to Chronic Otitis Media (COM): Preoperative Computed Tomographic Scan is Good Pointer for Sinister Lesions.

Indian J Otolaryngol Head Neck Surg 2018 Dec 30;70(4):505-509. Epub 2018 Aug 30.

Department of Otorhinolaryngology, Pt. B.D. Sharma, PGIMS, Rohtak, Haryana India.

Twenty five patients of aural polyp who underwent canal wall down mastoidectomy were analysed retrospectively. Histopathological examination revealed cholesteatoma in 22 (88%) patients. However, histopathological diagnosis in 3 of these patients was unusual and rare benign tumors of the middle ear cleft-meningioma, neurilemmoma and capillary hemangioma. Read More

View Article
December 2018
3 Reads

Comparison of a Smartphone Otoscope and Conventional Otoscope in the Diagnosis and Management of Acute Otitis Media.

Clin Pediatr (Phila) 2018 Nov 21:9922818812480. Epub 2018 Nov 21.

1 Emory University, Atlanta, GA, USA.

Acute otitis media (AOM) is a leading cause of health encounters and antimicrobial prescriptions in children worldwide. We assessed (1) the rates of antimicrobial prescribing by pediatric emergency department clinicians using a smartphone otoscope device as compared with a conventional otoscope and (2) clinician acceptability of the smartphone device. We conducted a randomized control study in children's hospital emergency departments over 6 months. Read More

View Article
November 2018

Characteristics of Intracranial Group A Streptococcal Infections in US Children, 1997-2014.

J Pediatric Infect Dis Soc 2018 Nov 21. Epub 2018 Nov 21.

Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.

Background: Few data on intracranial group A Streptococcus (GAS) infection in children are available. Here, we describe the demographic, clinical, and diagnostic characteristics of 91 children with intracranial GAS infection.

Methods: Cases of intracranial GAS infection in persons ≤18 years of age reported between 1997 and 2014 were identified by the Centers for Disease Control and Prevention's population- and laboratory-based Active Bacterial Core surveillance (ABCs) system. Read More

View Article
November 2018
3 Reads

Vaccines for Preventing Influenza in Healthy Individuals.

Authors:
Sally Liang

Acad Emerg Med 2018 Nov 21. Epub 2018 Nov 21.

Department of Emergency Medicine, SUNY Downstate Medical Center/Kings County Hospital Center.

Influenza is an acute respiratory infection that imposes a heavy burden on society. The illness itself usually lasts a few days but the residual symptoms of cough and malaise can last for weeks. In addition, it can cause complications such as otitis media, pneumonia, secondary bacterial pneumonia, exacerbations of chronic respiratory disease, bronchiolitis, febrile seizures, Reye's syndrome, and myocarditis. Read More

View Article
November 2018
4 Reads

A Comprehensive Review of Skull Base Osteomyelitis: Diagnostic and Therapeutic Challenges among Various Presentations.

Asian J Neurosurg 2018 Oct-Dec;13(4):959-970

Department of Neurology, University of New Mexico, Albuquerque, NM, USA.

Skull base osteomyelitis (SBO) is a complex and fatal clinical entity that is often misdiagnosed for malignancy. SBO is commonly a direct complication of otogenic, sinogenic, odontogenic, and rhinogenic infections and can present as central, atypical, or pediatric clival SBO. This review describes the clinical profile, investigational approach, and management techniques for these variants. Read More

View Article
November 2018
6 Reads

Outcome of Graft Uptake and Hearing Results between 'U' Flap Technique and Conventional Tympanomeatal Flap Technique for Anterior and Subtotal Tympanic Membrane Perforation.

J Nepal Health Res Counc 2018 Oct 30;16(3):297-301. Epub 2018 Oct 30.

Department of ENT- Head and Neck Surgery, Norvic International Hospital, Kathmandu, Nepal.

Background: Myringoplasty done for anterior and subtotal perforation needs expertise and practice than conventional underlay myringoplasty. The objective of this study was to compare the graft uptake and postoperative hearing results between 'U' flap and conventional tympanomeatal flap technique in anterior and subtotal tympanic membrane perforation.

Methods: Sixty three patients of age fifteen years and above with chronic otitis media mucosal type with any sized anterior and subtotal perforation of tympanic membrane were randomly allocated for myringoplasty by lottery method. Read More

View Article
October 2018
15 Reads

Infections of the Ear.

Emerg Med Clin North Am 2019 Feb;37(1):1-9

Department of Emergency Medicine, Kaiser Permanente, 4647 Zion Avenue, San Diego, CA 92120, USA. Electronic address:

Infections of the ear are a common presentation to an acute care environment. In this article, the authors aim to summarize the most common presentations, and diagnostic and treatment options for typical infections of the ear. This article is geared toward the emergency physician, urgent care provider, and primary care provider who will likely be the initial evaluating and treating provider to assist them in determining what treatment modalities can be managed in a clinic and what needs to be referred for admission or specialty consultation. Read More

View Article
February 2019
3 Reads

[A case report of papilloma of the eustachian tube with secretory otitis media].

Authors:
J Yang S Q Zhao

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Nov;53(11):851-852

Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

View Article
November 2018
2 Reads

Purification of a Conjugated Polysaccharide Vaccine using Tangential Flow Diafiltration.

Biotechnol Bioeng 2018 Nov 18. Epub 2018 Nov 18.

Department of Chemical Engineering, The Pennsylvania State University, University Park, PA.

Conjugated vaccines prepared from the capsular polysaccharide of Streptococcus pneumoniae can provide immunization against invasive pneumococcal disease, meningitis, and otitis media. One of the critical steps in the production of these vaccines is the removal of free (unreacted) polysaccharides from the protein-polysaccharide conjugate. Experimental studies were performed to evaluate the effects of membrane pore size, filtrate flux, and solution conditions on the transmission of both the conjugate and free polysaccharide through different ultrafiltration membranes. Read More

View Article
November 2018
4 Reads

Necrotizing Otitis Externa.

Intern Med 2018 Nov 19. Epub 2018 Nov 19.

Department of Infectious Diseases, St. Luke's International Hospital, Japan.

View Article
November 2018
2 Reads

Efficacy of fluralaner plus moxidectin (Bravecto® Plus spot-on solution for cats) against Otodectes cynotis infestations in cats.

Parasit Vectors 2018 Nov 19;11(1):595. Epub 2018 Nov 19.

MSD Animal Health Innovation GmbH, Research Antiparasitics, Zur Propstei, 55270, Schwabenheim, Germany.

Background: The efficacy of the fixed combination of fluralaner plus moxidectin for the treatment of Otodectes cynotis infestations was evaluated in cats after topical application.

Methods: Sixteen cats experimentally infested with O. cynotis were allocated randomly to two groups of 8 cats each. Read More

View Article
November 2018
1 Read

Syk and JNK signaling pathways are involved in inflammasome activation in macrophages infected with Streptococcus pneumoniae.

Biochem Biophys Res Commun 2018 Dec 14;507(1-4):217-222. Epub 2018 Nov 14.

College of Animal Science and Technology, Southwest University, Chongqing, 400715, China. Electronic address:

Streptococcus pneumoniae is a pathogen of significant clinical importance worldwide that can cause severe invasive diseases, such as pneumonia, otitis media and meningitis. Inflammsomes has been reported to participate in host defense against S. pneumoniae infection. Read More

View Article
December 2018
4 Reads

National quality evaluation of peri-surgical hearing care for pediatric otitis media with effusion.

Int J Qual Health Care 2018 Nov 15. Epub 2018 Nov 15.

Department of Otolaryngology, Cathay General Hospital, Taipei, Taiwan.

Objective: Otitis media with effusion (OME) is a common disease among children that can lead to grave sequelae with respect to hearing. Thus, when treating OME, appropriate hearing care should be provided; ventilation tube insertion (VTI), a standard approach for treating OME, is no exception. This study examined hearing care for VTI and its associated factors, especially at the national level. Read More

View Article
November 2018
3 Reads

Sudden Severe Unilateral Vestibulo-Cochlear Loss Due to Acute Staphylococcal Otitis Media.

Otol Neurotol 2018 Dec;39(10):e1168-e1170

Neurology Department, Royal Prince Alfred Hospital, Sydney, Australia.

View Article
December 2018
3 Reads