3,079 results match your criteria Otitis Externa


Indications for surgery in necrotizing otitis externa.

Eur Arch Otorhinolaryngol 2020 Jun 1. Epub 2020 Jun 1.

Department of Radiology, Medical University of Gdańsk, Smoluchowskiego 17, 80-214, Gdansk, Poland.

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http://dx.doi.org/10.1007/s00405-020-06092-7DOI Listing

Synchronous Occurrence of Bilateral Malignant Otitis Externa: Report of a Rare Case.

Korean J Fam Med 2020 May 27. Epub 2020 May 27.

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kota Bharu, Malaysia.

Malignant otitis externa (MOE) is a rare and potentially life-threatening disease of the ear and temporal bone. Bilateral simultaneous MOE is extremely rare. Due to bilaterally symmetrical facial nerve palsy, it can easily be missed at the initial presentation, causing delay in management. Read More

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http://dx.doi.org/10.4082/kjfm.20.0071DOI Listing

Cytological and microbiological characteristics of middle ear effusions in brachycephalic dogs.

J Vet Intern Med 2020 May 14. Epub 2020 May 14.

Royal (Dick) School of Veterinary Studies and The Roslin Institute, The University of Edinburgh, Midlothian, United Kingdom.

Background: Middle ear effusion is common in brachycephalic dogs with similarities to otitis media with effusion in children. Association with the cranial and eustachian tube morphology and bacterial infection is suspected in both species.

Hypothesis/objectives: To determine cytological and bacteriological features of middle ear effusions in dogs, provide information on histological features, and further assess the dog as a model of the human disease. Read More

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http://dx.doi.org/10.1111/jvim.15792DOI Listing

Inner-Ear Disorders Presenting with Air-Bone Gaps: A Review.

J Int Adv Otol 2020 Apr;16(1):111-116

Department of Medicine and Surgery, University of Salerno, Salerno, Italy.

Air-bone gaps (ABGs) are commonly found in patients with conductive or mixed hearing loss generally due to outer- and/or middle-ear diseases such as otitis externa, tympanic membrane perforation, interruption or fixation of the ossicular chain, and chronic suppurative otitis media. ABGs can also be found in correlation with inner-ear disorders, such as endolymphatic hydrops, enlarged vestibular aqueduct syndrome, semicircular canal dehiscence, gusher syndrome, cochlear dehiscence, and Paget disease's as well cerebral vascular anomalies including dural arteriovenous fistula. The typical clinical presentation of inner-ear conditions or cerebral vascular anomalies causing ABGs includes audiological and vestibular symptoms like vertigo, oscillopsia, dizziness, imbalance, spinning sensation, pulsatile or continuous tinnitus, hyperacusis, autophony, auricular fullness, Tullio's phenomenon, and Hennebert's sign. Read More

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http://dx.doi.org/10.5152/iao.2020.7764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224429PMC
April 2020
0.128 Impact Factor

Approaching Otolaryngology Patients During the COVID-19 Pandemic.

Otolaryngol Head Neck Surg 2020 May 12:194599820926144. Epub 2020 May 12.

Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA.

. To describe coronavirus disease 2019 (COVID-19) patient presentations requiring otolaryngology consultation and provide recommendations for protective measures based on the experience of ear, nose, and throat (ENT) departments in 4 Chinese hospitals during the COVID-19 pandemic. . Read More

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http://dx.doi.org/10.1177/0194599820926144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218357PMC
May 2020
1.721 Impact Factor

Management of Foreign Bodies in the Ear: A Retrospective Review of 123 Cases in Nigeria.

Ear Nose Throat J 2020 May 12:145561320920510. Epub 2020 May 12.

Department of Ear, Nose, and Throat Surgery, Federal Medical Centre, Ido Ekiti, Nigeria.

Foreign bodies in the ear are relatively common in emergency medicine. However, attempts at removal made outside the healthcare setting by untrained persons can result in complications of varying degrees. We conducted a 3-year retrospective review of 123 cases of aural foreign bodies at our hospital in Nigeria. Read More

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http://dx.doi.org/10.1177/0145561320920510DOI Listing
May 2020
0.881 Impact Factor

Diagnostic evaluation of a point-of-care test for culture and microbial susceptibility testing in canine dermatological infections in clinical practice.

Vet World 2020 Mar 20;13(3):521-529. Epub 2020 Mar 20.

Department of Veterinary Medicine (DIMEVET), University of Milan, via dell'Università 6, 26900 Lodi, Italy.

Background And Aim: Empirical antimicrobial therapy is frequently given in superficial bacterial folliculitis (SBF) and otitis externa (OE) in dogs, especially for the initial clinical presentation. Culture and subsequent antimicrobial susceptibility testing (AST) are generally limited to chronic cases with poor response to initial therapy. Several factors contribute to the failure to implement the use of AST in veterinary practice, i. Read More

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http://dx.doi.org/10.14202/vetworld.2020.521-529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183461PMC

Vestiges of Ossified Spheno-occipital Suture in an Elderly Patient With Down Syndrome and Lateral Skull Base Fracture.

In Vivo 2020 May-Jun;34(3):1427-1432

Department of Neuroradiology, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.

Background/aim: Down syndrome (DS) patients often show characteristic changes in the skull, e.g. short cranial base. Read More

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http://dx.doi.org/10.21873/invivo.11924DOI Listing
January 2020

Antimicrobial resistance and novel mutations detected in the gyrA and parC genes of Pseudomonas aeruginosa strains isolated from companion dogs.

BMC Vet Res 2020 Apr 15;16(1):111. Epub 2020 Apr 15.

Department of Veterinary Internal Medicine, Konkuk University College of Veterinary Medicine, Seoul, South Korea.

Background: Fluoroquinolone agents, such as enrofloxacin and marbofloxacin, are commonly used for pseudomonal infection in veterinary medicine. However, the rate of resistance to fluoroquinolones is rapidly increasing, according to multiple studies in various countries. Point mutations in the quinolone resistance-determining region (QRDR) are closely related to the increased fluoroquinolone resistance of Pseudomonas aeruginosa. Read More

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http://dx.doi.org/10.1186/s12917-020-02328-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158017PMC

[Fungal otitis externa in children: principles of diagnosis and rational therapy].

Vestn Otorinolaringol 2020 ;85(1):60-63

Sverzhevsky Research Clinical Institute of Otorhinolaryngology of the Moscow Healthcare Department, Moscow, Russia, 117152; Speransky Pediatric Municipal Clinical Hospital No. 9 of the Moscow Healthcare Department, Moscow, Russia, 123317.

Aim: To study the current diagnosis and treatment of fungal inflammation of the external auditory canal in children. This article summarizes the literature on predisposing factors for the occurrence of fungal infections of the external auditory canal in children.

Patients And Methods: In this study, we present modern approaches to the diagnosis and treatment of external fungal otitis media in children depending on the isolated genus and species of fungus. Read More

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http://dx.doi.org/10.17116/otorino20208501160DOI Listing
January 2020

Otomycosis Due to the Rare Fungi Talaromyces purpurogenus, Naganishia albida and Filobasidium magnum.

Mycopathologia 2020 Mar 30. Epub 2020 Mar 30.

Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Otomycosis is a common finding in otorhinolaryngology clinics and is usually caused by species of Candida and Aspergillus, particularly black aspergilli. Meanwhile, other fungi can give rise to this infection, and the identification of these requires accurate methods. Here, we report three cases of otomycosis due to rare fungal pathogens. Read More

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http://dx.doi.org/10.1007/s11046-020-00439-8DOI Listing

Malignant Otitis Externa: Causes for Various Treatment Responses.

J Int Adv Otol 2020 Apr;16(1):98-103

Clinic of Otorhinolaryngology and Maxillofacial Surgery, Clinical Center of Serbia, Belgrade, Serbia.

Objectives: Malignant (necrotizing) otitis externa (MOE) is an aggressive form of skin inflammation of the external ear with a tendency to spread infection to the temporal bone. The study aimed to evaluate a causal relationship between treatment responses and clinical features in patients with MOE.

Materials And Methods: In a retrospective, descriptive section study, the database was analyzed between January 2008 and December 2018 in our department, all patients with diagnosed MOE were identified. Read More

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http://dx.doi.org/10.5152/iao.2020.7709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224427PMC

Detection of a novel clone of Acinetobacter baumannii isolated from a dog with otitis externa.

Comp Immunol Microbiol Infect Dis 2020 Jun 19;70:101471. Epub 2020 Mar 19.

Istituto Zooprofilattico Sperimentale di Puglia e Basilicata, Sezione di Putignano, Contrada San Pietro Piturno, 70017, Putignano, BA, Italy.

In this study, the isolation of Acinetobacter baumannii in a dog with clinical bilateral otitis externa is described. Moreover, to investigate the zoonotic potential of the isolate, microbiological examinations on the family members were performed. An A. Read More

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http://dx.doi.org/10.1016/j.cimid.2020.101471DOI Listing

Author's response to letter to the editor: "Fungal otitis externa and wet ear with mucopurulent should be a influencing factors on tympanic membrane closure".

Eur Arch Otorhinolaryngol 2020 Mar 24. Epub 2020 Mar 24.

Department of ENT, Jeroen Bosch Hospital, 's Hertogenbosch, The Netherlands.

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http://dx.doi.org/10.1007/s00405-020-05917-9DOI Listing

Audiometric Outcomes and Middle Ear Disease following Cerebrospinal Fluid Leak Repair.

Otolaryngol Head Neck Surg 2020 Jun 24;162(6):942-949. Epub 2020 Mar 24.

Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University, Nashville, Tennessee, USA.

Objective: To investigate audiometric outcomes and incidence of chronic ear disease following lateral skull base repair (LSBR) of cerebrospinal fluid (CSF) leaks.

Study Design: Retrospective review.

Setting: Tertiary skull base center. Read More

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http://dx.doi.org/10.1177/0194599820911720DOI Listing

Management of otitis externa with an led-illuminated gel: a randomized controlled clinical trial in dogs.

BMC Vet Res 2020 Mar 20;16(1):91. Epub 2020 Mar 20.

School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione, 93/95, 62024, Matelica, MC, Italy.

Background: Canine otitis externa is a painful condition which can be challenging to treat due to difficulties in the administration of otic medication. This can be due to lack of owner compliance in the application of ear drops or due to the resentment that some dogs demonstrate when attempts are made to administer topical medication into a sensitive ear canal. The aim of the study was to assess the efficacy of a topical LED-illuminated gel (LIG) in canine otitis externa in comparison to standard of care therapy. Read More

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http://dx.doi.org/10.1186/s12917-020-02311-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083025PMC
March 2020
1.777 Impact Factor

Yeasts in Veterinary Dermatology: An Updated Overview.

Front Cell Infect Microbiol 2020 28;10:79. Epub 2020 Feb 28.

Department of Clinical Sciences and Services, Royal Veterinary College, Hatfield, United Kingdom.

Lipophilic yeasts of the genus are important skin commensals and opportunistic skin pathogens in a variety of animals. The species was first isolated from the skin of a captive Indian rhinoceros with an exfoliative dermatitis in 1925, recognized as an important otic pathogen of dogs in the 1950's, and finally accepted, after several years of controversy, as a common cause of canine dermatitis in the 1990's. Since then, there has been considerable research into the biology of yeasts and their interaction with their animal hosts. Read More

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http://dx.doi.org/10.3389/fcimb.2020.00079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059102PMC
February 2020

What is the Best Test for Diagnosis and Monitoring Treatment Response in Malignant Otitis Externa?

Laryngoscope 2020 Mar 11. Epub 2020 Mar 11.

Department of Otolaryngology- Head and Neck Surgery, Columbia University Irving Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1002/lary.28609DOI Listing

Aspergillus necrotizing otitis externa with temporomandibulozygomatic involvement.

Eur Ann Otorhinolaryngol Head Neck Dis 2020 Mar 2;137(2):127-129. Epub 2020 Mar 2.

Centre hospitalier de Valence, 26000 Valence, France.

Introduction: Aspergillus necrotizing otitis externa (NOE) is a rare disease, often associated with delayed diagnosis, the management of which is poorly defined.

Summary: The authors report a case of Aspergillus flavus necrotizing otitis externa with temporomandibular arthritis and temporozygomatic osteomyelitis with Staphylococcal coinfection in a diabetic patient. The diagnosis and discontinuation of treatment were guided by PET-CT scan. Read More

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http://dx.doi.org/10.1016/j.anorl.2019.09.010DOI Listing

Skull Base Osteomyelitis Complicated by Petrous Internal Carotid Artery Blowout.

Ear Nose Throat J 2020 Mar 5:145561320907164. Epub 2020 Mar 5.

Division of Otolaryngology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Skull base osteomyelitis (SBO) is an invasive infection of the external auditory canal, with involvement of the skull base, typically in the elderly diabetic population. Diagnosis may be challenging, as it requires a combination of clinical, laboratory, and radiographical findings. The mainstay of treatment is long-term antibiotic therapy, but surgical debridement of the temporal bone may be necessary in refractory cases. Read More

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http://dx.doi.org/10.1177/0145561320907164DOI Listing

Antimicrobial Activity of Garlic Derivatives on Common Causative Microorganisms of the External Ear Canal and Chronic Middle Ear Infections.

Turk Arch Otorhinolaryngol 2019 Dec 1;57(4):161-165. Epub 2019 Dec 1.

Department of Clinical Microbiology, Ankara Yıldırım Beyazıt University School of Medicine, Ankara, Turkey.

Objective: Today, antibiotic resistance is increasing and evolving into an important health problem. Therefore, it is important to research on alternative therapies to antibiotics. This study aimed to investigate the inhibitory effect of four garlic derivatives on microorganisms commonly isolated in ear infections. Read More

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http://dx.doi.org/10.5152/tao.2019.4413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032553PMC
December 2019

Unusual case of otomycosis caused by .

Med Mycol Case Rep 2020 Mar 7;27:68-71. Epub 2020 Feb 7.

Laboratory of Parasitology-Mycology, Habib Bourguiba Hospital, Sfax, Tunisia.

is a species of the order Mucorales rarely reported as a cause of human mucormycosis. We report an unusual case of otitis occurring in a diabetic woman after penetration of an insect in the right ear. Direct microscopic examination of the clinical sample showed hyaline and non septate hyphae belonging to the order Mucorales. Read More

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http://dx.doi.org/10.1016/j.mmcr.2020.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019119PMC

Surgery for necrotizing otitis externa-indications and surgical findings.

Eur Arch Otorhinolaryngol 2020 May 12;277(5):1327-1334. Epub 2020 Feb 12.

Department of Otolaryngology-Head and Neck Surgery, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Yitzhak I. Rager Blvd 151, 84101, Beer-Sheva, Israel.

Purpose: Treatment for necrotizing otitis externa (NOE) includes long term antibiotic and surgery in selected cases. Indications and extent of surgery, however, are still not defined. The aims of this study were: (1) present our experience in surgery for NOE (2) compare high-resolution computer tomography and perioperative findings (3) suggest recommendations for indications and extent of surgery. Read More

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http://dx.doi.org/10.1007/s00405-020-05842-xDOI Listing

Demography and commonly recorded clinical conditions of Chihuahuas under primary veterinary care in the UK in 2016.

BMC Vet Res 2020 Feb 12;16(1):42. Epub 2020 Feb 12.

Pathobiology and Population Science, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts, AL9 7TA, UK.

Background: The Chihuahua, the world's smallest dog breed, is a popular breed in the UK today. The VetCompass™ Programme collates de-identified clinical records from primary-care veterinary practices in the UK for epidemiological research. This study aimed to characterise the demography, age at death and common disorders of Chihuahuas under primary veterinary care during 2016 in the UK. Read More

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http://dx.doi.org/10.1186/s12917-020-2258-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014602PMC
February 2020

Aspergillus flavus malignant external otitis in a diabetic patient: case report and literature review.

Infection 2020 Apr 8;48(2):193-203. Epub 2020 Feb 8.

Service de Maladies Infectieuses Et Tropicales, APHP, Hôpital Bichat-Claude Bernard, 46, rue Henri Huchard, 75018, Paris, France.

Purpose: Malignant external otitis is an aggressive and potentially life-threatening infection. This rare disorder is typically caused by Pseudomonas aeruginosa and affects almost exclusively elderly diabetic patients. However, fungal malignant external otitis have been identified, especially in immunocompromised hosts. Read More

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http://dx.doi.org/10.1007/s15010-020-01394-8DOI Listing
April 2020
2.618 Impact Factor

Skin Infections and Outpatient Burn Management: Skin Infections in Patients With Diabetes.

Authors:
Maulik M Dhandha

FP Essent 2020 Feb;489:21-26

Maine-Dartmouth Family Medicine Residency, 15 East Chestnut St, Augusta, ME 04330.

Diabetes is associated with many complications, including foot ulcers. Individuals with diabetes have a 15% to 25% likelihood of developing a foot ulcer in their lifetime. The pathophysiologic mechanisms are multifactorial but the major etiologic factors are peripheral vascular disease and diabetic neuropathy. Read More

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February 2020

Fungal otitis externa and wet ear with mucopurulent should be influencing factors on tympanic membrane closure.

Authors:
Zhengcai Lou

Eur Arch Otorhinolaryngol 2020 May 25;277(5):1557-1558. Epub 2020 Jan 25.

Department of Otorhinolaryngology, Yiwu Central Hospital, 699 jiangdong road, Yiwu, 322000, Zhejiang, China.

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http://dx.doi.org/10.1007/s00405-020-05815-0DOI Listing

A review of thirty-nine patients diagnosed with necrotising otitis externa over three years: Is CT imaging for diagnosis sufficient?

Clin Otolaryngol 2020 May 5;45(3):414-418. Epub 2020 Feb 5.

Otolaryngology Department, Royal Hallamshire Hospital, Sheffield, UK.

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http://dx.doi.org/10.1111/coa.13507DOI Listing

Malignant Otitis Externa is Associated with Diabetes: A Population-Based Case-Control Study.

Ann Otol Rhinol Laryngol 2020 Jun 24;129(6):585-590. Epub 2020 Jan 24.

Sleep Research Center, Taipei Medical University Hospital, Taipei.

Objective: Despite studies reporting a possible association between malignant otitis externa (MOE) and diabetes, there are no large-scale population-based empirical studies. This nationwide, population-based case-control study explored the association of MOE occurrence with previously diagnosed diabetes.

Methods: Data were retrieved from Taiwan's National Health Insurance Research Database, 753 patients with MOE (cases) and 2 259 propensity score-matched patients without MOE (controls). Read More

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http://dx.doi.org/10.1177/0003489419901139DOI Listing

The otic microbiota and mycobiota in a referral population of dogs in eastern USA with otitis externa.

Vet Dermatol 2020 Jun 21;31(3):225-e49. Epub 2020 Jan 21.

Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey St, Philadelphia, PA, 19104, USA.

Background: Canine otitis externa (OE) is a common inflammatory disease that is frequently complicated by secondary bacterial and/or yeast infections. The otic microbial population is more complex than appreciated by cytological methods and aerobic culture alone.

Hypothesis/objectives: Differences in bacterial and fungal populations of the external ear canal will correlate with specific cytological and culture-based definitions of bacterial and Malassezia otitis. Read More

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http://dx.doi.org/10.1111/vde.12826DOI Listing

Complete genome sequence of a methicillin-resistant strain from canine otitis externa in Korea.

J Vet Sci 2020 Jan;21(1):e11

School of Bioresources and Bioscience, Chung-Ang University, Anseong 17546, Korea.

The increase in canine skin and soft tissue infections, such as pyoderma and otitis, caused by strains, is of significant zoonotic concern. In this study, we report the first complete genome sequence for a methicillin-resistant clinical isolate of (MRSS) designated as SS4, obtained from a dog with otitis externa, in Korea. The genome of SS4 strain was of 2,539,409 bp and presented high G+C content ratio (35. Read More

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http://dx.doi.org/10.4142/jvs.2020.21.e11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000899PMC
January 2020

Seasonal Variation Of Acute Otitis Externa Presenting To Ayub Teaching Hospital, Abbottabad.

J Ayub Med Coll Abbottabad 2019 Oct-Dec;31(4):569-571

PIMS Hospital, Islamabad, Pakistan.

Background: Otitis Externa is a common inflammatory condition of external ear. It is more common in patients having predisposing conditions like trauma, swimming, patients using hearing aids, certain skin pathologies and immunocompromised patients. Increased humidity in rainy season increases the predisposition to otitis externa. Read More

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Differential diagnosis of ear pain.

Cas Lek Cesk 2019 ;158(6):231-234

Ear pain, otalgia, can have many etiologies. Some of these conditions, e.g. Read More

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January 2020

Patulous Eustachian tube and palatine defect in a Dachshund with chronic unilateral otitis externa and otitis media.

Vet Dermatol 2020 Jun 6;31(3):240-e53. Epub 2020 Jan 6.

Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, 1352 Boyd Avenue, Saint Paul, MN, 55108, USA.

Background: Patulous Eustachian tube (pET) is a rare dysfunction of the Eustachian tube described in humans. It is characterized by failure of the ET to close, resulting in unrestricted passage of air, sound and material between the nasopharynx and the middle ear.

Objective: To report a case of pET associated with otitis in a dog. Read More

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http://dx.doi.org/10.1111/vde.12829DOI Listing

Matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for accurate discrimination of Staphylococcus schleiferi subspecies.

Vet Microbiol 2020 Jan 24;240:108472. Epub 2019 Oct 24.

Universidade Federal Fluminense, Instituto Biomédico, Niterói, RJ (Rua Professor Hernani Melo No 101, São Domingos, Niterói, RJ, CEP: 24210-130, Brazil. Electronic address:

S. schleiferi is one of the main species isolated from canine otitis externa, pyoderma and from apparently healthy dogs. The species is divided into two subspecies, S. Read More

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http://dx.doi.org/10.1016/j.vetmic.2019.108472DOI Listing
January 2020

Occult otitis media in dogs with chronic otitis externa - magnetic resonance imaging and association with otoscopic and cytological findings.

Vet Dermatol 2020 Apr 19;31(2):146-153. Epub 2019 Dec 19.

Animal Health Trust, Centre for Small Animal Studies, Lanwades Park, Kentford, Newmarket, CB8 7UU, UK.

Background: Identification of perpetuating factors, such as otitis media (OM), is important for the successful management of canine chronic otitis externa (OE).

Hypothesis/objectives: Occult OM can occur in cases of chronic OE; a focused magnetic resonance imaging (MRI) examination is a useful tool in their management.

Animals: One hundred twenty one client-owned dogs presented for investigation and treatment of chronic OE between 2009 and 2018. Read More

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http://dx.doi.org/10.1111/vde.12817DOI Listing

Response to Letter of Nevio Cimolai.

Otol Neurotol 2020 01;41(1):142

Department of Otolaryngology-Head and Neck Surgery, Soroka University Medical Center, Beer Sheva, Israel.

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http://dx.doi.org/10.1097/MAO.0000000000002514DOI Listing
January 2020

Clioquinol for Otomycosis: A Lesser Understood Antimicrobial.

Authors:
Nevio Cimolai

Otol Neurotol 2020 01;41(1):141-142

Department of Pathology and Laboratory Medicine, Faculty of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada, Department of Pathology and Laboratory Medicine, Children's and Women's Health Centre of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/MAO.0000000000002513DOI Listing
January 2020

Clinical profiling and management outcome of atypical skull base osteomyelitis.

Br J Neurosurg 2019 Dec 9:1-4. Epub 2019 Dec 9.

Department of ENT, Head, Neck and Skull Base Surgery, Apollo Specialty Cancer Hospital, Chennai, India.

Malignant otitis externa or skull base osteomyelitis arises as a complication of otological infection in immunocompromised individuals, especially elderly diabetics. With increasing awareness of the disease and better diagnostic modalities, there has been an increased reporting of atypical osteomyelitis of skull base (AOSB). Atypical osteomyelitis of skull base is a relatively rare yet an emerging clinical entity that also occurs in immunocompromised elderly individuals, however, in the absence of a pre-existing otological or rhinological infection. Read More

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http://dx.doi.org/10.1080/02688697.2019.1699905DOI Listing
December 2019

Partial vertical ear canal resection in two cats.

J Am Vet Med Assoc 2019 12;255(12):1365-1368

Case Description: An 18-year-old domestic medium-hair cat (cat 1) and a 16-year-old domestic shorthair cat (cat 2) were evaluated because of obstructive skin lesions involving the perimeter of the left external auditory canal.

Clinical Findings: Otitis externa was present in affected ears secondary to obstructive soft tissue growths involving the outer margin of the external auditory canal and outer third of the vertical ear canal. Histologic examination of a preoperative biopsy sample revealed multiple ulcerated ceruminous gland adenomas in the affected ear of cat 1. Read More

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http://dx.doi.org/10.2460/javma.255.12.1365DOI Listing
December 2019

Antifungal in vitro Activity of Essential Oils against Clinical Isolates of Malassezia pachydermatis from Canine Ears: A Report from a Practice Laboratory.

Complement Med Res 2019 Nov 27:1-12. Epub 2019 Nov 27.

Laboklin GmbH & Co. KG, Bad Kissingen, Germany.

Background: The yeast Malassezia pachydermatis is a commensal but also the most isolated pathogenic yeast in canine otitis externa. Essential oils (EOs) exhibit antimicrobial activity and thus could be an alternative for treatment of otitis.

Objective: The aim of this study was to analyse the in vitro efficacy of EOs against M. Read More

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http://dx.doi.org/10.1159/000504316DOI Listing
November 2019

Thirty-Day Readmission and Prolonged Length of Stay in Malignant Otitis Externa.

Laryngoscope 2019 Nov 22. Epub 2019 Nov 22.

Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, U.S.A.

Objectives: To determine independent risk factors for 30-day readmission, prolonged length of stay (PLOS), and discharge to a rehabilitation facility for those with malignant otitis externa.

Methods: Retrospective cohort study of patients hospitalized with malignant otitis externa (International Classification of Diseases, 9th edition, code 380.14) in the Nationwide Readmissions Database (2013-2014). Read More

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http://dx.doi.org/10.1002/lary.28409DOI Listing
November 2019

Meta-analysis does not support routine traditional nuclear medicine studies for malignant otitis.

Laryngoscope 2019 Nov 21. Epub 2019 Nov 21.

Department of Otolaryngology-Head & Neck Surgery, The Chinese University of Hong Kong, Shatin, HK.

Objectives: The role of traditional nuclear medicine studies in the management of malignant otitis externa (MOE) is unclear and there are ongoing debates regarding their diagnostic value. The authors perform a systematic review and meta-analysis to assess the sensitivity and specificity of traditional nuclear medicine studies in the diagnosis of MOE.

Methods: In accordance with PRISMA guidelines, a query of the Medline, Embase, Web of Science, and Cochrane databases was undertaken. Read More

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http://dx.doi.org/10.1002/lary.28411DOI Listing
November 2019

Appropriateness of Otic Quinolone Use among Privately Insured US Patients.

Otolaryngol Head Neck Surg 2020 01 19;162(1):102-107. Epub 2019 Nov 19.

Center for Drug Evaluation and Safety, University of Florida, Gainesville, Florida, USA.

Objective: Considering emerging safety concerns involving otic quinolones, we assessed the extent of otic quinolone use for questionable indications.

Study Design: Descriptive cross-sectional study of a national sample of privately insured patients.

Setting: Outpatient encounters in the United States. Read More

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http://dx.doi.org/10.1177/0194599819889607DOI Listing
January 2020
1.721 Impact Factor

Clinician adherence to the clinical practice guideline: Acute otitis externa.

Laryngoscope 2020 Jun 15;130(6):1565-1571. Epub 2019 Nov 15.

Department of Head and Neck Surgery & Communication Sciences, Duke University Health System, Durham, North Carolina, U.S.A.

Objectives/hypothesis: Over 10 years have passed since the Clinical Practice Guideline: Acute Otitis Externa (CPG-AOE) was first published, and it has been several years since its update. We sought to assess clinicians' adherence as well as referral patterns.

Study Design: Survey. Read More

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http://dx.doi.org/10.1002/lary.28339DOI Listing

In vitro antibacterial activity of the manuka essential oil from Leptospermum scoparium combined with Tris-EDTA against Gram-negative bacterial isolates from dogs with otitis externa.

Vet Dermatol 2020 Apr 15;31(2):81-85. Epub 2019 Nov 15.

Laboratory of Veterinary Dermatology, The Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea.

Background: The increasing prevalence of antimicrobial resistance among bacteria in dogs with otitis externa has led to a need for novel therapeutic agents.

Hypothesis/objective: To examine the antibacterial effects of manuka oil combined with ethylenediaminetetraacetic acid-tromethamine (Tris-EDTA) against Gram-negative bacteria isolates from dogs with otitis externa.

Methods And Materials: A total of 53 clinical isolates including Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae ssp. Read More

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http://dx.doi.org/10.1111/vde.12807DOI Listing

Diagnosis and Antibiotic Management of Otitis Media and Otitis Externa in United States Veterans.

Open Forum Infect Dis 2019 Nov 4;6(11):ofz432. Epub 2019 Oct 4.

Boise VA Medical Center, Boise, Idaho, USA.

Background: Acute otitis media (AOM) and otitis media with effusion (OME) occur primarily in children, whereas acute otitis externa (AOE) occurs with similar frequency in children and adults. Data on the incidence and management of otitis in adults are limited. This study characterizes the incidence, antibiotic management, and outcomes for adults with otitis diagnoses. Read More

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http://dx.doi.org/10.1093/ofid/ofz432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837836PMC
November 2019

Case Report: Case report: A rare case of middle-ear Rhabdomyosarcoma in a 4-year-old boy.

F1000Res 2019 9;8:1734. Epub 2019 Oct 9.

Ear, Nose and Throat Department, Brighton and Sussex University Hospitals, Brighton, UK.

We present a rare case of a four-year-old boy with a botyroid embryonal rhabdomyosarcoma of the right middle ear. Rhabdomyosarcoma is a soft tissue malignancy which is thought to originate from embryonic mesenchymal cells of striated skeletal muscle.  It is a disease primarily of children and is exceptionally rare in parameningeal regions. Read More

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http://dx.doi.org/10.12688/f1000research.20558.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823896PMC