2,952 results match your criteria Otitis Externa


Fungal Malignant Otitis Externa Involves a Cascade of Complications Culminating in Pseudoaneurysm of Internal Maxillary Artery: A Case Report.

Am J Case Rep 2019 Apr 21;20:562-566. Epub 2019 Apr 21.

Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.

BACKGROUND Pseudomonal infection is the most common cause of malignant otitis externa (MOE), which typically affects elderly diabetic patients. Fungi are a rare cause of MOE. MOE can be life-threatening if not recognized and treated promptly. Read More

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https://www.amjcaserep.com/abstract/index/idArt/913469
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http://dx.doi.org/10.12659/AJCR.913469DOI Listing
April 2019
1 Read

Myeloid sarcoma presenting as bilateral acute otitis externa in newly diagnosed acute myeloid leukemia.

Int J Pediatr Otorhinolaryngol 2019 Apr 3;122:126-129. Epub 2019 Apr 3.

Division of Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, OH, USA.

Myeloid sarcoma (MS) is an extramedullary collection of immature myeloid cells that can commonly occur with acute myeloid leukemia (AML). While head and neck presentations are not unheard of, there have been few published pediatric cases of external auditory canal MS. Here, we report a case of a 14-year-old male who presented with MS masquerading as bilateral acute otitis externa. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.04.002DOI Listing

Tubercular Otitis Externa in an Elderly Male- A Case Report.

Iran J Otorhinolaryngol 2019 Mar;31(103):127-130

Medical Research Laboratory, IMS and SUM Hospital, Siksha "O" Anusandhan (Deemed to be University), K8, Kalinganagar, Bhubaneswar-751003, Odisha, India.

Introduction: Tuberculosis is one of the most common diseases in developing countries, resulting in significant morbidity and mortality. Tuberculosis has varied clinical presentations, varying from common primary pulmonary tuberculosis to the extremely rare tubercular otitis externa, as in this case. Tubercular otitis externa has an extremely low clinical incidence. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449525PMC
March 2019
2 Reads

Candida albicans skull base osteomyelitis due to malignant otitis externa: the role of echinocandin therapy associated with surgical debridement.

Enferm Infecc Microbiol Clin 2019 Apr 10. Epub 2019 Apr 10.

Servicio de Otorrinolaringología, Hospital Universitario 12 de Octubre, Madrid, España.

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http://dx.doi.org/10.1016/j.eimc.2019.02.006DOI Listing
April 2019
1 Read

Malignant otitis externa, an increasing burden in the twenty-first century: review of cases in a UK teaching hospital, with a proposed algorithm for diagnosis and management.

J Laryngol Otol 2019 Apr 12:1-7. Epub 2019 Apr 12.

Otolaryngology Head and Neck Department,Sheffield Teaching Hospitals NHS Foundation Trust,UK.

Background: Malignant otitis externa is a potentially fatal infection of the skull base. With an ageing population and increasing prevalence of diabetes, the incidence of malignant otitis externa in the British population is rising. To date, there remain no accepted diagnostic criteria, few prognostic indicators and no consensus treatment pathways. Read More

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http://dx.doi.org/10.1017/S0022215119000604DOI Listing
April 2019
1 Read

Malignant otitis externa complicated by multiple cervical-petrous internal carotid artery pseudoaneurysms: a case report.

Hong Kong Med J 2019 Apr;25(2):152-155

Department of Neurosurgery, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong.

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http://dx.doi.org/10.12809/hkmj165016DOI Listing
April 2019
1 Read

Rare case of a 3-year-old with skull base osteomyelitis: lessons to be learnt.

BMJ Case Rep 2019 Apr 8;12(4). Epub 2019 Apr 8.

Ear, Nose and Throat Surgery, Lister Hospital, Stevenage, UK.

Skull base osteomyelitis (SBO) is a serious and rare condition most commonly seen in elderly diabetic or immunocompromised patients as a complication of otitis externa. We present the case of a previously healthy 3-year-old girl who presented to the paediatric emergency department with vomiting, fever, lethargy, headache and left-sided facial nerve palsy. The initial CT head revealed left-sided otitis media with otomastoiditis and she was managed with intravenous antibiotics and myringotomy with grommet insertion with initial improvement. Read More

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http://dx.doi.org/10.1136/bcr-2018-228026DOI Listing
April 2019
1 Read

An unusual case of feline otitis externa due to sporotrichosis.

JFMS Open Rep 2019 Jan-Jun;5(1):2055116919840810. Epub 2019 Mar 29.

Department of Veterinary Medicine and Surgery, Rural Federal University of Rio de Janeiro, Seropédica, Brazil.

Case Summary: It is described a case of a 10-month-old female mixed-breed cat with left ear discharge of approximately 6 days' duration prior to the admission. Secretions were collected from both ears using a sterile swab for cytological and mycological analysis. A pyogranulomatous inflammatory infiltrate (predominantly characterized by the presence of neutrophils and macrophages) with the presence of cocci, rods and many yeast-like structures were seen on cytological analysis; the fungal culture confirmed the presence of the complex. Read More

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http://dx.doi.org/10.1177/2055116919840810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442078PMC
March 2019
1 Read

Carriage of from canine otitis externa: antimicrobial resistance profiles and virulence factors associated with skin infection.

J Vet Sci 2019 Mar 8;20(2):e6. Epub 2019 Mar 8.

Department of Animal Science and Technology, School of Bioresources and Bioscience, Chung-Ang University, Anseong 17546, Korea.

The recent emergence of in dogs with otitis externa or skin and soft tissue infections has become a significant zoonotic issues. In the current study, we investigated 1) the carriage rates of among major staphylococci in healthy dogs and dogs with otitis externa, 2) antibiotic susceptibility profiles of particularly methicillin resistance (MR), and 3) virulence factors associated with skin and soft tissue infections such as ability to form biofilm, resistance to cationic antimicrobial peptides (CAMPs), and carriage of staphylococcal enterotoxin genes. Among the 21 isolates, 5 isolates (24%) were determined to be methicillin-resistant (MRSS). Read More

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http://dx.doi.org/10.4142/jvs.2019.20.e6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441802PMC
March 2019
2 Reads

Quantification of Malassezia pachydermatis by real-time PCR in swabs from the external ear canal of dogs.

J Vet Diagn Invest 2019 Apr 4:1040638719840686. Epub 2019 Apr 4.

Veterinary Mycology Group, Department of Animal Health and Anatomy, Universitat Autònoma de Barcelona, Bellaterra, Catalonia, Spain.

Malassezia pachydermatis is part of the normal microbiota of canine skin and external ear canal, and is also associated with otitis externa in dogs. Laboratory detection of Malassezia otitis relies on the presence of elevated numbers of the yeast on cytologic examination of otic exudate. Although cytology has high specificity, it has low sensitivity, resulting in false-negatives and posing a challenge for clinicians to accurately diagnose Malassezia otitis. Read More

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http://dx.doi.org/10.1177/1040638719840686DOI Listing
April 2019
3 Reads

Extensive Skull Base Osteomyelitis Secondary to Malignant Otitis Externa.

J Int Adv Otol 2019 Mar 29. Epub 2019 Mar 29.

Infectious Disease Unit, University Hospital of Pisa, Pisa, Italy.

Skull base osteomyelitis is a severe complication of malignant otitis externa that affects the marrow of the temporal, sphenoid, and occipital bones. Skull base osteomyelitis is usually diagnosed based on clinical, microbiological, and radiological findings. Here, we present the imaging findings of a 76-year-old man who initially presented with right-sided malignant otitis externa, with the involvement of the otomastoid structures and ipsilateral temporal bone. Read More

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http://dx.doi.org/10.5152/iao.2019.5406DOI Listing
March 2019
1 Read

Effects of an enrofloxacin-silver sulfadiazine emulsion in the ears of rabbits with perforated tympanic membranes.

Am J Vet Res 2019 Apr;80(4):325-334

Objective: To determine whether an enrofloxacin-silver sulfadiazine emulsion (ESS) labeled for treatment of otitis externa in dogs has ototoxic effects in rabbits following myringotomy.

Animals: 6 healthy adult New Zealand White rabbits.

Procedures: Rabbits were anesthetized for brainstem auditory-evoked response (BAER) tests on day 0. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.325DOI Listing
April 2019
1 Read

A case of otitis externa caused by Schizophyllum commune: An approach to antimicrobial stewardship using Gram staining of otorrhea in a medical clinic.

J Infect Chemother 2019 Mar 21. Epub 2019 Mar 21.

Department of Clinical Laboratory Science, Faculty of Health Care, Tenri Health Care University, Tenri, Japan.

Recently, basidiomycete Schizophyllum commune has been reported as a cause of allergic bronchopulmonary mycosis. However, it is rare as a cause of otitis externa. We experienced a very rare case of otitis externa caused by S. Read More

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http://dx.doi.org/10.1016/j.jiac.2019.03.005DOI Listing
March 2019
1 Read

Malignant Aspergillus flavus Otitis Externa with Jugular Thrombosis.

Emerg Infect Dis 2019 Apr;25(4):830-832

We report a case of malignant otitis externa with jugular vein thrombosis caused by Aspergillus flavus. Magnetic resonance imaging revealed an unusual ink smudge pattern deep in a cervical abscess. The pattern was consistent with mycetoma and may be important for diagnosing these life-threatening infections. Read More

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http://dx.doi.org/10.3201/eid2504.180710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433013PMC
April 2019
1 Read

Otoscopy and aural cytological findings in a population of rescue cats and cases in a referral small animal hospital in England and Wales.

J Feline Med Surg 2019 Mar 18:1098612X19834969. Epub 2019 Mar 18.

2 Highcroft Veterinary Referrals, Bristol, UK.

Objectives: Otitis externa is seen clinically in cats, although studies investigating this condition within the UK are lacking. The objective of this study was to investigate the prevalence of Otodectes cynotis mites and microbial infection in the ear canals of cats in various rescue centres and a referral hospital.

Methods: Otoscopy was performed in 332 cats. Read More

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http://dx.doi.org/10.1177/1098612X19834969DOI Listing
March 2019
1 Read

Schwannoma of the external auditory canal: An exceptional site.

Eur Ann Otorhinolaryngol Head Neck Dis 2019 Mar 12. Epub 2019 Mar 12.

Centre hospitalier universitaire Mohammed VI Oujda Université 60049, Oujda, Morocco.

Introduction: Schwannomas are benign solitary neural tumours that are only exceptional located in the external auditory canal, as only a few cases have been reported in the literature.

Case Report: We report a case of schwannoma of the external auditory canal in an 18-year-old man admitted for an isolated mass of the initial segment of the right external auditory canal visible to the naked eye, obstructing all of the external auditory meatus. Computed tomography of the temporal bone showed an isolated mass of the external auditory canal. Read More

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http://dx.doi.org/10.1016/j.anorl.2019.02.014DOI Listing
March 2019
2 Reads

Malignant otitis externa in a 21-year-old male patient with Prader-Willi syndrome.

SAGE Open Med Case Rep 2019 5;7:2050313X19834827. Epub 2019 Mar 5.

Department of Internal Medicine, Universidade Federal de Santa Maria, Santa Maria, Brazil.

Malignant otitis externa is an invasive infection of the external auditory canal and temporal bone with potentially life-threatening complications. Elderly patients with type 2 diabetes mellitus are the population most commonly affected by malignant otitis externa, but any type of immunosuppression predisposes to the disease. Prader-Willi syndrome is a genetic cause of obesity, often associated with insulin resistance and type 2 diabetes mellitus. Read More

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http://journals.sagepub.com/doi/10.1177/2050313X19834827
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http://dx.doi.org/10.1177/2050313X19834827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404052PMC
March 2019
6 Reads

Cotton bud in external ear canal causing necrotising otitis externa and subdural abscess.

BMJ Case Rep 2019 Mar 6;12(3). Epub 2019 Mar 6.

Department of Otolaryngology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.

Necrotising otitis externa (NOE) is an infection originating in the soft tissues of the external auditory canal (EAC) spreading to the surrounding bone and rarely causing intracranial complications. It is usually caused by and has historically occurred in elderly patients with diabetes or immunodeficiency. EAC foreign body is a risk factor for otitis externa but has not been described in NOE. Read More

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http://dx.doi.org/10.1136/bcr-2018-227971DOI Listing
March 2019
3 Reads

Skull base osteomyelitis: factors implicating clinical outcome.

Acta Neurol Belg 2019 Mar 6. Epub 2019 Mar 6.

Department of Otolaryngology, Medical University of Warsaw, Warsaw, Poland.

Skull base osteomyelitis is a serious disease with a high risk of complications including neuroinfection. Typically, the inflammation of the skull base results from infection from neighboring tissues. In case of malignant otitis externa, inflammation disseminates from the external auditory canal. Read More

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http://link.springer.com/10.1007/s13760-019-01110-w
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http://dx.doi.org/10.1007/s13760-019-01110-wDOI Listing
March 2019
9 Reads

OTO-201 for the Treatment of Acute Otitis Externa: Results from a Phase 3 Randomized Clinical Study.

Ann Otol Rhinol Laryngol 2019 Mar 2:3489419830116. Epub 2019 Mar 2.

3 Otonomy, Inc., San Diego, CA, USA.

Objectives:: OTO-201 is a ciprofloxacin otic suspension previously approved by the US Food and Drug Administration to treat children with bilateral otitis media with effusion requiring tympanostomy tube placement. In this phase 3, double-blind, randomized, prospective, sham-controlled, multicenter study, a single dose of OTO-201 was administered to the external auditory canal in subjects with unilateral or bilateral acute otitis externa.

Methods:: Two hundred sixty-two subjects, 3 to 83 years of age, were randomized, and 260 subjects were included in the intent-to-treat analysis population: OTO-201 (0. Read More

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http://journals.sagepub.com/doi/10.1177/0003489419830116
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http://dx.doi.org/10.1177/0003489419830116DOI Listing
March 2019
5 Reads

Characterization of the otic bacterial microbiota in dogs with otitis externa compared to healthy individuals.

Vet Dermatol 2019 Mar 4. Epub 2019 Mar 4.

Department of Pathobiology, Ontario Veterinary College, University of Guelph, 50 Stone Road E, Guelph, Ontario, Canada, N1G 2W1.

Background: Otitis externa is a common multifactorial disease in dogs. The diversity of the cutaneous microbiota in dogs appears to decrease in diseased states. However, little is known about the microbiota of the canine ear and how it is altered by disease. Read More

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http://dx.doi.org/10.1111/vde.12734DOI Listing
March 2019
1 Read

Medical and Audiological Indications for Implantable Auditory Devices.

Otolaryngol Clin North Am 2019 Apr;52(2):195-210

Department of Otolaryngology, Long Island Jewish Medical Center, Hearing and Speech Center, Northwell Health, 430 Lakeville Road, New Hyde Park, NY 11042, USA.

Implantable auditory devices (IADs) are a viable hearing restoration option for patients with hearing loss. Conditions such as chronic otitis externa, congenital aural atresia, and chronic otitis media can be treated with a variety of implants. Progressive disease are also amenable to restoration with IADs, providing stabilized hearing. Read More

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http://dx.doi.org/10.1016/j.otc.2018.11.001DOI Listing
April 2019
3 Reads

When to refer: Validating the Evidence-based Acute Otitis Externa Referral Score (EARS). Our experience of 287 cases of otitis externa in primary care.

Clin Otolaryngol 2019 Feb 20. Epub 2019 Feb 20.

Mersey ENT Research Collaborative (MERC), Liverpool, UK.

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http://dx.doi.org/10.1111/coa.13320DOI Listing
February 2019
2 Reads

Miniature Schnauzers under primary veterinary care in the UK in 2013: demography, mortality and disorders.

Canine Genet Epidemiol 2019 15;6. Epub 2019 Feb 15.

Bath Veterinary Referrals, Rosemary Lodge, Wellsway, Bath, BA2 5RL UK.

Background: Individual dog breeds are often reported as predisposed to specific breed-related disorders but reliable epidemiological data on disease prevalence are sparse. The Miniature Schnauzer in the UK is a popular small breed dog that is often considered as relatively healthy and long-lived, but is this really true? This study aimed to use data from the VetCompass™ Programme at the Royal Veterinary College to characterise the demography, mortality and common disorders of the general population of Miniature Schnauzers under veterinary care in the UK.

Results: The study population of 455,557 dogs from 304 clinics in the VetCompass™ database under veterinary care during 2013 included 3857 Miniature Schnauzers (0. Read More

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http://dx.doi.org/10.1186/s40575-019-0069-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376765PMC
February 2019
2 Reads

Treatment of Selected Canine Dermatological Conditions in Portugal - A Research Survey.

J Vet Res 2018 Dec 31;62(4):563-570. Epub 2018 Dec 31.

Department of Veterinary Sciences, Escola de Ciências Agrárias e Veterinárias, University of Trás-os-Montes and Alto Douro (UTAD), 5001-801 Vila Real, Portugal.

Introduction: and often cause skin diseases in dogs.

Material And Methods: An online survey was e-mailed to veterinary practices nationwide covering demographics, diagnosis methods, and oral and topical treatment options. Of the 740 surveys sent, 100 complete replies were obtained. Read More

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http://dx.doi.org/10.2478/jvetres-2018-0058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364160PMC
December 2018
2 Reads

Malignant otitis externa in Australian Aboriginal patients: A 9-year retrospective analysis from the Northern Territory.

Aust J Rural Health 2019 Feb 30;27(1):78-82. Epub 2019 Jan 30.

Otolaryngology Head and Neck Surgery, Royal Darwin Hospital, Tiwi, Northern Territory, Australia.

Objective: In the Australian Aboriginal population, type 2 diabetes occurs at a much higher prevalence, with a much younger age of onset of the disease and its complications. Despite the clear association with malignant otitis externa, no previous studies have examined malignant otitis externa in this population. This study explores the pattern of malignant otitis externa amongst Australian Aboriginal patients in the Northern Territory. Read More

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http://dx.doi.org/10.1111/ajr.12468DOI Listing
February 2019
6 Reads

The Impact of using the term "Diabetic Ear" for the patients with Skull Base Osteomyelitis.

J Family Community Med 2019 Jan-Apr;26(1):23-29

Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Imam Abdulrahman Bin Faisal University, KFUH, Al-Khobar, Saudi Arabia.

Background: Diabetes and ear disease are some of the most widespread health concerns. The focus here is on the impact of using the term "Diabetic Ear" for patients with skull base osteomyelitis (SBM) in the context of malignant otitis externa (MOE). The aim of this study was to discover the awareness of general practitioners (GPs), residents, specialists, and consultants at Primary Health Care Centers about necrotizing otitis externa (NOE), also known previously as malignant external otitis (MOE), assess their deficiencies and provide solutions; also assist them for the early detection and possible prevention of diabetes- related ear diseases and their complications. Read More

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http://dx.doi.org/10.4103/jfcm.JFCM_187_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335838PMC
January 2019
7 Reads

Determination of minimum inhibitory concentrations for silver sulfadiazine and other topical antimicrobial agents against strains of Pseudomonas aeruginosa isolated from canine otitis externa.

Vet Dermatol 2019 Apr 20;30(2):145-e42. Epub 2019 Jan 20.

Small Animal Medicine Clinic, Centre for Clinical Veterinary Medicine, Faculty of Veterinary Medicine, Ludwig-Maximilian University, Veterinärstraße 13, 80539, Munich, Germany.

Background: Otitis externa is a common presenting complaint in practice. Ear infections by Pseudomonas aeruginosa are particularly problematic due to the organism's high level of resistance and ability to damage the tympanum. Treatment should be based on susceptibility testing although minimum inhibitory concentrations (MICs) are not available for all treatment options. Read More

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http://dx.doi.org/10.1111/vde.12718DOI Listing
April 2019
2 Reads

Canine otitis externa - Treatment and complications.

Authors:
Jangi Bajwa

Can Vet J 2019 Jan;60(1):97-99

Dr. Bajwa is a Board-certified Veterinary Dermatologist, Veterinary Dermatology & Ear Referral Medical Clinic, Vancouver, British Columbia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294027PMC
January 2019
3 Reads

Clinical analysis and nonsurgical management of 11 dogs with aural cholesteatoma.

Vet Dermatol 2019 Feb;30(1):42-e12

Dermatology Service, Synergy Animal General Hospital, 815 Ishigami, Kawaguchi, Saitama, 333-0823, Japan.

Background: Aural cholesteatomas, also called tympanokeratomas, are destructive and expansile growths of keratinizing epithelium that develop in the middle ear. They have been reported sporadically in dogs, and surgery is usually the recommended treatment.

Objectives: To describe the common clinical, radiological and histological findings of cholesteatoma; to report on the outcome of conservative management. Read More

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http://dx.doi.org/10.1111/vde.12707DOI Listing
February 2019
7 Reads

Nocardial clival osteomyelitis secondary to sphenoid sinusitis: an atypical skull base infection.

Acta Neurochir (Wien) 2019 Mar 3;161(3):529-534. Epub 2019 Jan 3.

Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175 North Medical Drive East, Salt Lake City, UT, 84132, USA.

Clival osteomyelitis is a life-threatening complication of untreated malignant otitis externa or paranasal sinus infection. Although various pathogens have been implicated, to our knowledge, primary nocardial clival osteomyelitis has never been reported. We describe a 74-year-old woman who presented with headaches, abducens and hypoglossal nerve palsies, facial numbness, photophobia, and neck stiffness. Read More

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http://dx.doi.org/10.1007/s00701-018-3768-5DOI Listing
March 2019
6 Reads

Hypertrophic recurring lichen planus of the external auditory canal.

Eur Ann Otorhinolaryngol Head Neck Dis 2019 Apr 31;136(2):123-126. Epub 2018 Dec 31.

School of Medicine, University of Zagreb, Šalata 3b, Zagreb, Croatia.

Introduction: We report a case of unilateral progressive primary hypertrophic lichen planus of the external auditory canal requiring several surgical interventions to deal with constant pruritus, otorrhoea, stenosis and conductive hearing loss.

Case Summary: A 58-year-old woman was initially treated with meatoplasty for suspected chronic obliterating otitis externa. She remained symptom-free for 5 years, before the disease recurred, affecting other body surfaces as well. Read More

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http://dx.doi.org/10.1016/j.anorl.2017.12.013DOI Listing
April 2019
7 Reads

Effective treatment and decolonization of a dog infected with carbapenemase (VIM-2)-producing Pseudomonas aeruginosa using probiotic and photodynamic therapies.

Vet Dermatol 2019 Jan 3. Epub 2019 Jan 3.

Department of Clinical Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Orlando M. Paiva, 580, São Paulo, SP, 05508-000, Brazil.

Background: Carbapenem-resistant bacterial infections are a critical problem in veterinary medicine with limited treatment options.

Objective: To describe effective probiotic and photodynamic therapy of a dog with gut colonization and ear infection caused by a hospital-associated lineage of carbapenemase (VIM-2)-producing Pseudomonas aeruginosa.

Animals: A 5-year-old Lhasa apso dog presented with otitis externa. Read More

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http://dx.doi.org/10.1111/vde.12714DOI Listing
January 2019
8 Reads

Methicillin-resistant in acute otitis externa.

World J Otorhinolaryngol Head Neck Surg 2018 Dec 23;4(4):246-252. Epub 2017 Nov 23.

Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA.

Objective: Otologic methicillin-resistant (MRSA) infection has historically been rare, but given the rise in community-acquired MRSA carriage and infection at other body sites, prevalence rates may be changing. The goal of this study was to determine the prevalence of MRSA in recent otologic cultures from patients with acute otitis externa (AOE).

Study Design: Retrospective review of an institutional microbiologic database. Read More

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http://dx.doi.org/10.1016/j.wjorl.2017.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284227PMC
December 2018
3 Reads

Genomic Tandem Quadruplication is Associated with Ketoconazole Resistance in .

J Microbiol Biotechnol 2018 Nov;28(11):1937-1945

Department of Systems Biotechnology, Chung-Ang University, Anseong 17546, Republic of Korea.

is a commensal yeast found on the skin of dogs. However, is also considered an opportunistic pathogen and is associated with various canine skin diseases including otitis externa and atopic dermatitis, which usually require treatment using an azole antifungal drug, such as ketoconazole. In this study, we isolated a ketoconazole-resistant strain of , designated "KCTC 27587," from the external ear canal of a dog with otitis externa and analyzed its resistance mechanism. Read More

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http://dx.doi.org/10.4014/jmb.1810.10019DOI Listing
November 2018
2 Reads

A Lateral Neck Myeloid Sarcoma Presenting as Acute Otitis Externa.

Arch Iran Med 2018 Nov 1;21(11):544-546. Epub 2018 Nov 1.

Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.

Myeloid sarcoma (MS) is a solid extra-medullary tumor of immature myeloid cells which could occur before, during or after remission of acute leukemia at any site on the body. Owing to variation in differential diagnosis, pathologic evaluation and immunohistochemical staining are essential for definitive diagnosis. Rarely, MS has been shown as an isolated extramedullary relapse (iEMR) after allogeneic stem cell transplantation (allo-SCT), which often does not necessarily result in bone marrow involvement. Read More

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November 2018
2 Reads

In vitro antimicrobial activity of seven adjuvants against common pathogens associated with canine otitis externa.

Vet Dermatol 2019 Apr 13;30(2):133-e38. Epub 2018 Dec 13.

Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia, 5371, Australia.

Background: An antibiotic adjuvant is a chemical substance used to modify or augment the effectiveness of primary antimicrobial agents against drug-resistant micro-organisms. Its use provides an alternative approach to address the global issue of antimicrobial resistance and enhance antimicrobial stewardship.

Hypothesis/objectives: To determine the antimicrobial activity of a panel of potential antimicrobial adjuvants against common pathogens associated with canine otitis externa (OE). Read More

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http://dx.doi.org/10.1111/vde.12712DOI Listing
April 2019
8 Reads
1.732 Impact Factor

The proportion, conditions, and predictors of emergency department visits that can be potentially managed by pharmacists with expanded scope of practice.

Res Social Adm Pharm 2018 Dec 7. Epub 2018 Dec 7.

School of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, N2G 1C5, ON, Canada; Ontario Pharmacy Evidence Network (OPEN), School of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, N2G 1C5, ON, Canada.

Background: Pharmacists have been shown to be beneficial for inclusion in emergency department (ED) services; however, little has been done to assess these benefits with pharmacists having even wider scopes of practice, including limited prescribing authority.

Objectives: The aims of this study were to determine the proportion of ED visits that can potentially be managed by pharmacists, the most prevalent conditions within these cases, and the factors associated with patients presenting with such cases to the ED.

Methods: This was a retrospective quantitative cohort study using administrative databases from 2010 to 2017. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15517411183101
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http://dx.doi.org/10.1016/j.sapharm.2018.12.003DOI Listing
December 2018
33 Reads

Additive value of Technetium methylene diphosphonate hybrid single-photon emission computed tomography/computed tomography in the diagnosis of skull base osteomyelitis in otitis externa patients compared to planar bone scintigraphy.

World J Nucl Med 2018 Oct-Dec;17(4):286-292

Department of Oncology and Nuclear Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.

The aim of this study was to evaluate the additive value of technetium methylene diphosphonate (Tc-MDP) hybrid single-photon emission computed tomography/computed tomography (SPECT-CT) in the diagnosis of skull base osteomyelitis (SBO) compared to planar bone scintigraphy (PBS). This was a single institution; prospective study included 23 patients with otitis externa, clinically suspected of SBO, all of them were diabetic. Three-phase bone scintigraphy and SPECT/CT were performed to all patients. Read More

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http://dx.doi.org/10.4103/wjnm.WJNM_88_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216726PMC
December 2018
2 Reads

The Role of Surgical Debridement in Cases of Refractory Malignant Otitis Externa.

Indian J Otolaryngol Head Neck Surg 2018 Dec 18;70(4):549-554. Epub 2018 Jun 18.

Sri Guru Ram Das Institute of Health Sciences and Research Amritsar, 27-C; Sant Avenue, The Mall, Amritsar, 143001 India.

Malignant Otitis externa is a necrotizing condition of external ear involving causing the osteomyelitis of the bone and surrounding soft tissue leading to multiple cranial nerve palsies. Though most patients respond to oral ciprofloxacin but due to emerging resistance cases of refractory malignant otitis externa which are unresponsive to antibiotic therapy for at least 6 weeks are being encountered lately. A study of 20 patients of refractory malignant otitis Externa was conducted at a tertiary care centre in north India; 10 patients were randomly allotted in group A and group B each. Read More

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http://dx.doi.org/10.1007/s12070-018-1426-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224839PMC
December 2018
15 Reads

A Comprehensive Review of Skull Base Osteomyelitis: Diagnostic and Therapeutic Challenges among Various Presentations.

Asian J Neurosurg 2018 Oct-Dec;13(4):959-970

Department of Neurology, University of New Mexico, Albuquerque, NM, USA.

Skull base osteomyelitis (SBO) is a complex and fatal clinical entity that is often misdiagnosed for malignancy. SBO is commonly a direct complication of otogenic, sinogenic, odontogenic, and rhinogenic infections and can present as central, atypical, or pediatric clival SBO. This review describes the clinical profile, investigational approach, and management techniques for these variants. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_90_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208218PMC
November 2018
16 Reads

Infections of the Ear.

Emerg Med Clin North Am 2019 Feb;37(1):1-9

Department of Emergency Medicine, Kaiser Permanente, 4647 Zion Avenue, San Diego, CA 92120, USA. Electronic address:

Infections of the ear are a common presentation to an acute care environment. In this article, the authors aim to summarize the most common presentations, and diagnostic and treatment options for typical infections of the ear. This article is geared toward the emergency physician, urgent care provider, and primary care provider who will likely be the initial evaluating and treating provider to assist them in determining what treatment modalities can be managed in a clinic and what needs to be referred for admission or specialty consultation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07338627183008
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http://dx.doi.org/10.1016/j.emc.2018.09.001DOI Listing
February 2019
7 Reads

Necrotizing Otitis Externa.

Intern Med 2019 Mar 19;58(6):895-896. Epub 2018 Nov 19.

Department of Infectious Diseases, St. Luke's International Hospital, Japan.

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https://www.jstage.jst.go.jp/article/internalmedicine/advpub
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http://dx.doi.org/10.2169/internalmedicine.1684-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465003PMC
March 2019
14 Reads

Efficacy of fluralaner plus moxidectin (Bravecto® Plus spot-on solution for cats) against Otodectes cynotis infestations in cats.

Parasit Vectors 2018 Nov 19;11(1):595. Epub 2018 Nov 19.

MSD Animal Health Innovation GmbH, Research Antiparasitics, Zur Propstei, 55270, Schwabenheim, Germany.

Background: The efficacy of the fixed combination of fluralaner plus moxidectin for the treatment of Otodectes cynotis infestations was evaluated in cats after topical application.

Methods: Sixteen cats experimentally infested with O. cynotis were allocated randomly to two groups of 8 cats each. Read More

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http://dx.doi.org/10.1186/s13071-018-3167-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241040PMC
November 2018
4 Reads

Use of physician billing claims to identify infections in children.

PLoS One 2018 12;13(11):e0207468. Epub 2018 Nov 12.

Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

While medical records have detailed information, they are limited in reach to the availability and accessibility of those records. On the other hand, administrative data while limited in scope, have a much further reach in coverage of an entire population. However, few studies have validated the use of administrative data for identifying infections in pediatric populations. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0207468PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231686PMC
April 2019
3 Reads

otitis externa in dogs.

Authors:
Charlie Pye

Can Vet J 2018 Nov;59(11):1231-1234

Dr. Pye BSc, DVM, DVSc, Diplomate ACVD is an Assistant Professor, Atlantic Veterinary College, Charlottetown, Prince Edward Island.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190182PMC
November 2018
6 Reads

Acute otitis externa because of negative pressure wound therapy applied over the head and ear canal for scalping treatment.

Int Wound J 2019 Apr 31;16(2):559-563. Epub 2018 Oct 31.

Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto-SP, Brazil.

Scalping is considered a complex wound with difficult treatment, requiring early surgical intervention, reconstructive plastic surgery, and a multidisciplinary team. The reconstruction of the scalp frequently requires a combination of therapies, including temporary coverage, such as negative pressure wound therapy (NPWT). Complications of NPWT, such as bleeding, infection, and pain, have been described. Read More

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http://dx.doi.org/10.1111/iwj.13012DOI Listing
April 2019
6 Reads

Labrador retrievers under primary veterinary care in the UK: demography, mortality and disorders.

Canine Genet Epidemiol 2018 22;5. Epub 2018 Oct 22.

3Pathobiology and Population Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA UK.

Background: Labrador retrievers are reportedly predisposed to many disorders but accurate prevalence information relating to the general population are lacking. This study aimed to describe demography, mortality and commonly recorded diseases in Labrador retrievers under UK veterinary care.

Methods: The VetCompass™ programme collects electronic patient record data on dogs attending UK primary-care veterinary practices. Read More

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http://dx.doi.org/10.1186/s40575-018-0064-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196571PMC
October 2018
3 Reads

Hearing loss in the trenches - a hidden morbidity of World War I.

Authors:
K Conroy V Malik

J Laryngol Otol 2018 Nov 29;132(11):952-955. Epub 2018 Oct 29.

Department of Otolaryngology,Blackpool Victoria Hospital,UK.

Background: One hundred years ago, millions of British and Allied troops were fighting in the trenches of the Great War. With a tenth of soldiers losing their lives, hearing loss seemed a low priority; however, vast numbers of troops sustained significant hearing loss.

Method: A review was conducted of literature published between 1914 and 1925. Read More

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https://www.cambridge.org/core/product/identifier/S002221511
Publisher Site
http://dx.doi.org/10.1017/S0022215118001755DOI Listing
November 2018
14 Reads

Complicated Necrotizing Otitis Externa Progressing to Coalescent Mastoiditis and Temporal Lobe Abscess.

Am J Med 2019 Feb 25;132(2):e39-e40. Epub 2018 Oct 25.

Department of Pulmonary, Critical Care and Sleep Medicine, MedStar Georgetown University Hospital, Washington, DC.

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http://dx.doi.org/10.1016/j.amjmed.2018.10.005DOI Listing
February 2019
2 Reads