Hua Xi Kou Qiang Yi Xue Za Zhi 2021 Oct;39(5):524-530
Dept. of Stomatology, Daping Hospital, Army Medical University, Chongqing 400042, China.
Objectives: To compare the effects of different irradiators on the establishment of osteoradionecrosis of jaw model (ORNJ) to explore an ideal modeling method.
Methods: A total of 33 adult SD rats were included and randomly divided into three groups according to the radiation equipment, namely, the blank control (CN, 3 rats), group A (linear accelerator irradiation, 15 rats), and group B (small-animal irradiator irradiation, 15 rats). Groups A and B were irradiated with daily fractions of 7, 8, and 9 Gy for 5 days and further divided into three subgroups as follows: group A/B, 35 Gy; group A/B, 40 Gy; and group A/B, 45 Gy. Read More