6,374 results match your criteria Osteonecrosis Hip


The diagnostic value of SPECT/CT in predicting the occurrence of osteonecrosis following femoral neck fracture: a prospective cohort study.

BMC Musculoskelet Disord 2020 Aug 3;21(1):517. Epub 2020 Aug 3.

Department of Orthopedic Surgery, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.

Backgrounds: One of the most significant complications after a femoral neck fracture is osteonecrosis of the femoral head (ONFH). The concomitant use of single-photon emission computed tomography (SPECT) with computed tomography (CT) increases the sensitivity for detecting the anatomic location and severity of ONFH. In this study, we evaluated the diagnostic value of SPECT/CT for the occurrence of ONFH by quantifying the perfusion status of the femoral head. Read More

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http://dx.doi.org/10.1186/s12891-020-03538-1DOI Listing

Modified technique of advanced core decompression for treatment of femoral head osteonecrosis.

World J Clin Cases 2020 Jul;8(13):2749-2757

Center of Integrative Research, The First Hospital of Qiqihar, Qiqihaer 161005, Heilongjiang Province, China.

Background: Osteonecrosis of the femoral head (ONFH) is a destructive condition most commonly affecting young and middle-aged patients. The leading consequence of ONFH is often a significant articular disability. Effective joint-preserving surgical treatments are urgently needed for patients with early stage ONFH when outcomes of treatment are in general better than the advanced stage disease. Read More

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http://dx.doi.org/10.12998/wjcc.v8.i13.2749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360713PMC

Fixation using Alternative Implants for the Treatment of Hip Fractures (FAITH-2): The Clinical Outcomes of a Multi-Centre 2x2 Factorial Randomized Controlled Pilot Trial in Young Femoral Neck Fracture Patients.

J Orthop Trauma 2020 Jul 24. Epub 2020 Jul 24.

R Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, Maryland, 21201, USA.

Objective: To assess whether fixation method and vitamin D supplementation impact the risk of patient important outcomes within 12 months of injury in non-geriatric femoral neck fracture patients.

Design: Pilot factorial randomized controlled trial.

Setting: 15 North American clinical sites. Read More

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http://dx.doi.org/10.1097/BOT.0000000000001773DOI Listing

Total Hip Arthroplasty in Black/African American Patients: an Updated Nationwide Analysis.

J Racial Ethn Health Disparities 2020 Jul 28. Epub 2020 Jul 28.

Department of Orthopaedic Surgery, Baylor College of Medicine, 7200 Cambridge Street, Suite 10A, Houston, TX, 77030, USA.

Background: The purpose of this was to investigate recent trends in procedure utilization, comorbidity profiles, hospital length of stay (LOS), 30-day outcomes, and risk factors for adverse events (AEs) among Black patients undergoing total hip arthroplasty (THA).

Methods: Using the American College of Surgeons National Surgery Quality Improvement Program, we retrospectively reviewed all Black patients who underwent elective, primary THA between 2011 and 2017. Mixed effects logistic regression analyses were performed to determine the trends in the study outcomes across each individual year. Read More

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http://dx.doi.org/10.1007/s40615-020-00829-0DOI Listing

Reduced serum and local LncRNA MALAT1 expressions are linked with disease severity in patients with non-traumatic osteonecrosis of the femoral head.

Technol Health Care 2020 Jul 15. Epub 2020 Jul 15.

Department of Orthopedics, Linyi People's Hospital, Linyi, Shandong, China.

Objective: This study was performed to illustrate the potential relationship between reduced serum and local LncRNA MALAT1 expressions with disease severity in patients with non-traumatic osteonecrosis of the femoral head (ONFH).

Methods: A total of 104 patients with non-traumatic ONFH and 100 healthy controls were consecutively recruited from our hospital. Serum and local LncRNA MALAT1 expressions were detected using real-time polymerase chain reaction (RT-PCR). Read More

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http://dx.doi.org/10.3233/THC-202244DOI Listing

Bone marrow lesion on magnetic resonance imaging indicates the last chance for hip osteonecrosis treated with vascularized fibular grafting before collapse.

Int Orthop 2020 Jul 26. Epub 2020 Jul 26.

Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai, China.

Purpose: Timing of surgery is the most critical prognostic factor for hip osteonecrosis treated with free vascularized fibular grafting (FVFG). Bone marrow lesion (BML) on MRI usually occurs immediately before femoral head collapse. We conducted a retrospective cohort study to evaluate whether the noncollapsed hips with BML can benefit from FVFG. Read More

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http://dx.doi.org/10.1007/s00264-020-04697-5DOI Listing

Hip survival after plain core decompression alone versus bone morphogenetic protein and/or bone marrow reinjection with core decompression for avascular osteonecrosis of the femoral head: a retrospective case control study in ninety two patients.

Int Orthop 2020 Jul 21. Epub 2020 Jul 21.

CHU Lille, Hôpital Salengro, University of Lille, Hauts de France, F-59000, Lille, France.

Introduction: Injecting bone marrow or bone morphogenetic protein 7 (BMP) during core decompression for avascular osteonecrosis (AVN) may improve survival. We hypothesized that adding a complementary technique (injection of BMP and/or non-concentrated bone marrow) to core decompression would reduce the number of patients requiring a subsequent total hip arthroplasty (THA).

Methods: We retrospectively reviewed 92 cases from 2003 to 2018 with a minimum of 2 years of follow-up and an average follow-up of 64 months (24-204). Read More

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http://dx.doi.org/10.1007/s00264-020-04692-wDOI Listing

Study on the outcome of patients with aseptic femoral head necrosis treated with percutaneous multiple small-diameter drilling core decompression: a retrospective cohort study based on magnetic resonance imaging and equivalent sphere model analysis.

J Orthop Surg Res 2020 Jul 15;15(1):264. Epub 2020 Jul 15.

Department of Joint Surgery and Sports Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.

Background: Aseptic necrosis of the femoral head (ANFH) has a high incidence in the community and causes substantial problems with health as well as economic and social stress. Core decompression is the most commonly used treatment for early ANFH. Although many studies have reported on the efficacy of femoral head core decompression surgery for ANFH, there are still some shortcomings in assessing the severity of femoral head necrosis, the location distribution, and changes in necrotic lesions before and after surgery. Read More

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http://dx.doi.org/10.1186/s13018-020-01786-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362550PMC
July 2020
1.577 Impact Factor

Osteoclastic activity was associated with the development of steroid-induced osteonecrosis of femoral head.

Artif Cells Nanomed Biotechnol 2020 Dec;48(1):1036-1046

The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, PR China.

This study is focussed on evaluating and comparing two mediators of osteoclast, osteoprotegerin (OPG) and nuclear factor-κB ligand (RANKL), in plasma and tissue levels in patients with steroid-induced osteonecrosis of femoral head (SIONFH). Subjects were included in this cross-sectional case-control study in 2016. Bone histomorphology, immunohistochemistry, Western blotting, OPG and RANKL plasma levels, statistical power and receiver-operating characteristic (ROC) curves were evaluated. Read More

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http://dx.doi.org/10.1080/21691401.2020.1774596DOI Listing
December 2020

Treatments of avascular osteonecrosis of the hip: Current treatments.

Authors:
P Massin

Morphologie 2020 Jul 8. Epub 2020 Jul 8.

CMC Ambroise-Paré-Hartmann, 3, rue de l'Hôtel-de-Ville, 92200 Neuilly-sur-Seine, France. Electronic address:

Conservative treatments for aseptic osteonecrosis of the femoral head have their ancestor in the core decompression of the femoral neck, recommended by Ficat. Due to inconsistent results, this treatment has been optimized by either vascularized fibular grafting, or by injecting autologous stem cells into the necrotic zone. The French promoters have published long-term results, showing efficacy in the early stages of the disease, where the femoral head has not yet lost its sphericity. Read More

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http://dx.doi.org/10.1016/j.morpho.2020.06.003DOI Listing

Surgical dislocation or the modified Heuter anterior approach for Pipkin I and II femoral head fracture dislocations.

J Orthop Trauma 2020 Jun 29. Epub 2020 Jun 29.

Objectives: To compare outcomes after surgical treatment of Pipkin I and II femoral head fractures treated with either a surgical dislocation (SD) or a direct anterior approach (The Modified Heuter Approach) STUDY DESIGN:: Retrospective, multi - centre SETTING:: Three Level I trauma care centres PATIENTS:: 49 patients operated for Pipkin types I or II femoral head fractures. 27 - using SD and 22 - using modified Heuter approach.

Interventions: Initial closed reduction of the joint followed by open reduction and internal fixation of the fracture/ fragment excision. Read More

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http://dx.doi.org/10.1097/BOT.0000000000001877DOI Listing
June 2020
1.540 Impact Factor

Subchondral fracture of the femoral head in children: Differential diagnosis of pediatric hip pain.

J Orthop Surg (Hong Kong) 2020 Jan-Apr;28(2):2309499020937862

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

This report describes clinical and radiographic characteristics of two pediatric patients with a presumptive diagnosis of subchondral fracture of the femoral head made based on their clinical course and imaging findings. An 8-year-old boy and an 8-year-old girl had subchondral fracture in the femoral head without osteonecrosis, which was verified by contrast-enhanced magnetic resonance imaging. Although complete disappearance of the fracture line was confirmed in the boy, the girl had a residual femoral head deformity after conservative treatment. Read More

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http://dx.doi.org/10.1177/2309499020937862DOI Listing

Comparative safety and effectiveness of alendronate versus raloxifene in women with osteoporosis.

Sci Rep 2020 Jul 6;10(1):11115. Epub 2020 Jul 6.

Department of Computational Medicine, University of California, Los Angeles, CA, 90095, USA.

Alendronate and raloxifene are among the most popular anti-osteoporosis medications. However, there is a lack of head-to-head comparative effectiveness studies comparing the two treatments. We conducted a retrospective large-scale multicenter study encompassing over 300 million patients across nine databases encoded in the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM). Read More

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http://dx.doi.org/10.1038/s41598-020-68037-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338498PMC

Spectrum of magnetic resonance imaging findings in transplanted multiple myeloma patients with hip/pelvic pain (according to MY-RADS): A single center experience.

Eur J Radiol 2020 Jun 24;130:109154. Epub 2020 Jun 24.

Department of Health Sciences (DISSAL), University of Genoa, Genova, Italy; Department of Radiology, IRCCS San Martino Hospital, Genova, Italy.

Purpose: The aim of our study is to evaluate the spectrum of MRI findings in transplanted Multiple Myeloma (MM) patients with hip/pelvic pain and to correlate these findings with standard prognostic clinical outcomes.

Methods: A retrospective interpretation of the MRI findings of 54 MM patients with hip/pelvic pain were done according to MY-RADS guidelines. MRI findings included: type of bone marrow involvement and incidental findings (osteonecrosis and fractures). Read More

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http://dx.doi.org/10.1016/j.ejrad.2020.109154DOI Listing

Histopathological Findings of Failed Free Vascularized Fibular Grafting for Osteonecrosis of the Femoral Head after Long-Term Follow-Up.

Biomed Res Int 2020 14;2020:6493585. Epub 2020 Jun 14.

Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai 200233, China.

Purpose: The aim of this study was to report the histopathology of failed free vascularized fibular grafting (FVFG) for osteonecrosis of the femoral head (ONFH) after a mean follow-up of 11.5 years (ranged from 10.6 to 14. Read More

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http://dx.doi.org/10.1155/2020/6493585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313102PMC

Long-term results in the patients with traumatic hip fracture-dislocation: Important prognostic factors.

J Chin Med Assoc 2020 Jul;83(7):686-689

Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.

Background: Traumatic hip dislocation with or without acetabular fractures can lead to various outcomes of the hip. Long-term follow-up studies on traumatic hip dislocation are few. We conducted a retrospective study of the treatment and long-term outcomes in patients with hip dislocation to determine prognostic factors. Read More

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http://dx.doi.org/10.1097/JCMA.0000000000000366DOI Listing

Neck modularity in total hip arthroplasty: a retrospective study of nine hundred twenty-eight titanium neck implants with a maximum follow-up of eighteen years.

Int Orthop 2020 Jun 29. Epub 2020 Jun 29.

Major Hospital, Parma, Italy.

Purpose: Neck modularity was introduced to improve total hip arthroplasty (THA) accuracy, but it has been associated with early breakages and corrosion issues. In our hospital, modular necks have been in clinical use since the 1990s. We retrospectively analysed the occurrence of these sequelae in implants placed between January 2000 and December 2014. Read More

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http://dx.doi.org/10.1007/s00264-020-04686-8DOI Listing

Management of osteonecrosis of the femoral head.

Bone Joint J 2020 Jul;102-B(7_Supple_B):122-128

Department of Orthopaedic Surgery, Lenox Hill Hospital, Northwell Health, New York, New York, USA.

Aims: Earlier studies dealing with trends in the management of osteonecrosis of the femoral head (ONFH) identified an increasing rate of total hip arthroplasties (THAs) and a decreasing rate of joint-preserving procedures between 1992 and 2008. In an effort to assess new trends in the management of this condition, this study evaluated the annual trends of joint-preserving versus arthroplasties for patients aged < or > 50 years old, and the incidence of specific operative management techniques.

Methods: A total of 219,371 patients with ONFH were identified from a nationwide database between 1 January 2009 and 31 December 2015. Read More

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http://dx.doi.org/10.1302/0301-620X.102B7.BJJ-2019-1611.R1DOI Listing

Optimizing indications of impacting bone allograft transplantation in osteonecrosis of the femoral head.

Bone Joint J 2020 Jul;102-B(7):838-844

Institute of Orthopedics, Guangzhou University of Chinese Medicine, Guangzhou, China.

Aims: The aim of this study was to report the medium-term outcomes of impaction bone allograft and fibular grafting for osteonecrosis of the femoral head (ONFH) and to define the optimal indications.

Methods: A total of 67 patients (77 hips) with ONFH were enrolled in a single centre retrospective review. Success of the procedure was assessed using the Harris Hip Score (HHS) and rate of revision to total hip arthroplasty (THA). Read More

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http://dx.doi.org/10.1302/0301-620X.102B7.BJJ-2019-1101.R2DOI Listing

Avascular necrosis of the femoral head due to low-dose corticosteroid used in a patient with panhypopituitarism: A case report and literature review.

Jt Dis Relat Surg 2020 18;31(2):390-394. Epub 2020 Jun 18.

Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Kliniği, 06110 Dışkapı, Ankara, Türkiye.

Osteonecrosis, commonly known as avascular necrosis (AVN) of bone, is one of the universally recognized side effects of high-dose steroids and commonly involves femur head leading to significant morbidity. However, the development of AVN in the femoral head due to low-dose oral corticosteroid therapy in a short time is a rare occurrence. Management by stopping corticosteroid treatment can be challenging in many cases due to the adrenal crisis. Read More

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http://dx.doi.org/10.5606/ehc.2020.72773DOI Listing

Combined Imhauser osteotomy and osteochondroplasty in slipped capital femoral epiphysis through surgical hip dislocation approach.

J Child Orthop 2020 Jun;14(3):190-200

Department of Orthopaedic Surgery, Faculty of Medicine, Ain-Shams University, Cairo, Egypt.

Purpose: Treatment of moderate to severe stable slipped capital femoral epiphysis (SCFE) remains a challenging problem. Open reduction by modified Dunn procedure carries a considerable risk of osteonecrosis (ON). Imhauser osteotomy is capable of realigning the deformity without the risk of ON, but the remaining metaphyseal bump is implicated with significant chondro-labral lesions and accelerated osteoarthritis. Read More

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http://dx.doi.org/10.1302/1863-2548.14.200021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302412PMC

Incidence and risk factors for osteonecrosis of the hip in renal transplant patients: a prospective single-centre study.

Int Orthop 2020 Jun 23. Epub 2020 Jun 23.

Department of Orthopaedic Surgery, Japanese Red Cross Nagoya Daini Hospital, 2-9 Myouken-cho Showa-ku, Nagoya, 466-8650, Japan.

Background: There is a lack of evidence about the risk factors associated with osteonecrosis of the femoral head (ONFH).

Purposes: To determine the incidence and risk factors for ONFH following renal transplantation (RT).

Methods: In total, data of 681 RT patients (mean age at surgery, 49. Read More

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http://dx.doi.org/10.1007/s00264-020-04668-wDOI Listing

H subtype vascular endothelial cells in human femoral head: an experimental verification.

Ann Palliat Med 2020 Jun 22. Epub 2020 Jun 22.

Department of Orthopedics, China-Japan Friendship Hospital, National Health and Family Planning Commission of the People's Republic of China, Beijing, China.

Background: Osteonecrosis of the femoral head (ONFH) is difficult to treat, and leads to an impaired microcirculation of the femoral head and activation of a repair response. The type H vessels have been proved to mediate the growth of the bone vasculature and couple angiogenesis to osteogenesis. The aim of the study is to investigate the experimental verification of H subtype vascular endothelial cells (HSVECs) in the human femoral head. Read More

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http://dx.doi.org/10.21037/apm-20-121DOI Listing

Efficacy of bone marrow stem cells combined with core decompression in the treatment of osteonecrosis of the femoral head: A PRISMA-compliant meta-analysis.

Medicine (Baltimore) 2020 Jun;99(25):e20509

Department of Orthopedics, Fuzhou Second Hospital affiliated to Xiamen University, Fuzhou, Fujian Province, China.

Background: This study used the meta-analytic approach to assess the safety and treatment efficacy of bone marrow stem cells (BMSCs) with core decompression (CD) for osteonecrosis of the femoral head (ONFH) based on randomized controlled trials (RCTs).

Methods: Electronic database of PubMed, Embase, Google Scholar, China National Knowledge Infrastructure (CNKI), and Wanfang database was searched up to December 26, 2019 for relevant RCTs about combined utilization of BMSCs and CD versus CD alone for ONFH. Gray literature sources were also searched. Read More

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http://dx.doi.org/10.1097/MD.0000000000020509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310908PMC

Is bone marrow edema syndrome a precursor of hip or knee osteonecrosis? Results of 49 patients and review of the literature.

Diagn Interv Radiol 2020 Jul;26(4):355-362

Department of Radiology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.

Purpose: Diagnosis of bone marrow edema syndrome (BMES) can be challenging. There is sometimes uncertainty about the correct diagnosis of BMES on morphologic magnetic resonance imaging (MRI), since subchondral findings like lines and spots can be misinterpreted as "beginning" or "possible" avascular osteonecrosis (AVN). The aim of our study was to systematically assess the temporal course of BMES from first diagnosis on MRI until the end of clinical symptoms and the full disappearance of bone marrow edema (BME) to determine whether subchondral lines and spots detected in these patients can develop into osteonecrosis. Read More

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http://dx.doi.org/10.5152/dir.2020.19188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360071PMC

Magnetic Targeting of HU-MSCs in the Treatment of Glucocorticoid-Associated Osteonecrosis of the Femoral Head Through Akt/Bcl2/Bad/Caspase-3 Pathway.

Int J Nanomedicine 2020 21;15:3605-3620. Epub 2020 May 21.

Scientific Research Center, China-Japan Union Hospital of Jilin University, Changchun, Jilin, People's Republic of China.

Purpose: Osteonecrosis of the femoral head (ONFH) is a chronic and irreversible disease that eventually develops into a joint collapse and results in joint dysfunction. Early intervention and treatment are essential for preserving the joints and avoiding hip replacement. In this study, a system of human umbilical mesenchymal stem cells-supermagnetic iron oxide nanoparticles (NPs) @polydopamine (SCIOPs) was constructed. Read More

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http://dx.doi.org/10.2147/IJN.S244453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247730PMC

Serum exosomal hsa-miR-135b-5p serves as a potential diagnostic biomarker in steroid-induced osteonecrosis of femoral head.

Am J Transl Res 2020 15;12(5):2136-2154. Epub 2020 May 15.

Hip Center, Guangzhou University of Chinese Medicine Guangzhou 510405, China.

Accumulating studies have demonstrated serum exosomal microRNAs (miRNAs) represent novel biomarkers for various diseases. In this study, we aimed to explore the feasibility of using serum exosomal miRNAs as novel serological biomarkers for steroid-induced osteonecrosis of femoral head (SONFH). We identified the characters of exosomes which were obtained from fresh serum of 5 systemic lupus erythematosus (SLE) patients without SONFH, 5 SLE patients with SONFH (SLE-SONFH) and 5 healthy ones. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269975PMC

Digital Subtraction Angiography and Magnetic Resonance Imaging-Based Staging of Circulatory Obstruction in the Femoral Head During Osteonecrosis of the Femoral Head Development.

Ann Plast Surg 2020 Jun 2. Epub 2020 Jun 2.

From the Department of Orthopedics.

Introduction: Nontraumatic osteonecrosis of the femoral head (NONFH) is a common and difficult disease in orthopedics. Magnetic resonance imaging (MRI) assessment of NONFH and bone marrow edema was combined with digital subtraction angiography (DSA) to evaluate the circulatory status of NONFH in different Association Research Circulation Osseous stages. Based on the circulatory obstruction status (venous stasis, arterial ischemia, and arterial occlusion), appropriate perioperative management was adopted to achieve hip joint preservation and effectively delay the time for total hip arthroplasty in young patients. Read More

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http://dx.doi.org/10.1097/SAP.0000000000002424DOI Listing

Fibula allograft propping as an effective treatment for early-stage osteonecrosis of the femoral head: a systematic review.

J Orthop Surg Res 2020 Jun 3;15(1):206. Epub 2020 Jun 3.

Department of Joint Surgery, Aviation General Hospital, Courtyard 3, AnwaiBeiyuan, Chaoyang District, Beijing, China.

Background: Osteonecrosis of the femoral head (ONFH) causes severe hip dysfunction. Left untreated, 80% of patients experience femoral head collapse, and 65-70% of patients require total hip arthroplasty (THA). Therefore, effective treatment is very important for ONFH. Read More

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http://dx.doi.org/10.1186/s13018-020-01730-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268760PMC

Core Decompression Combined with Implantation of Autologous Bone Marrow Concentrate with Tricalcium Phosphate Does Not Prevent Radiographic Progression in Early Stage Osteonecrosis of the Hip.

Clin Orthop Surg 2020 Jun 6;12(2):151-157. Epub 2020 May 6.

Hip Unit, Department of Orthopedic Surgery, University Hospital of Vall d'Hebron, Universitat Autónoma de Barcelona, Barcelona, Spain.

Backgroud: Untreated osteonecrosis of the femoral head ultimately leads to secondary coxarthrosis. The aim of this study was to determinate if the core decompression of the femoral head combined with implantation of autologous bone marrow concentrate with tricalcium phosphate could be used to prevent radiographic progression of early stage osteonecrosis of the hip. We also sought to determine whether this treatment improved clinical outcomes and reduced the need for total hip arthroplasty. Read More

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http://dx.doi.org/10.4055/cios19033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237257PMC

Treatment of avascular osteonecrosis of femoral head by core decompression and platelet-rich plasma: a prospective not controlled study.

Int Orthop 2020 Jul 1;44(7):1287-1294. Epub 2020 Jun 1.

Clinical Orthopedics, Department of Clinical and Molecular Science, School of Medicine, Università Politecnica delle Marche, via Tronto 10/A, 60126, Torrette di Ancona, Italy.

Purpose: Core decompression is a surgical option since the 1960s for hip osteonecrosis treatment. This technique promotes bone repair by reducing intramedullary pressure, but this is not often enough to stop the progression of necrosis. The aim of this study was to associate core decompression with the regenerative stimulus provided by platelet-rich plasma (PRP) and compare our results with other regenerative techniques. Read More

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http://dx.doi.org/10.1007/s00264-020-04628-4DOI Listing

Risk factors for radiological changes after bipolar hemiarthroplasty for osteonecrosis of the femoral head.

Mod Rheumatol 2020 Jul 14:1-8. Epub 2020 Jul 14.

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Objectives: This study aimed to report the mid-term radiological outcomes of patients with bipolar hemiarthroplasty (BHA) for stage 3 osteonecrosis of the femoral head (ONFH), and to identify the risk factors for postoperative radiological changes.

Methods: We retrospectively investigated 62 patients (38 men and 24 women; mean age, 50.1 years) aged <70 years who underwent primary BHA for Association Research Circulation Osseous stage 3 ONFH between 1998 and 2010. Read More

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http://dx.doi.org/10.1080/14397595.2020.1775959DOI Listing

Whole-joint magnetic resonance imaging to assess osteonecrosis in pediatric patients with acute lymphoblastic lymphoma.

Pediatr Blood Cancer 2020 Aug 30;67(8):e28336. Epub 2020 May 30.

Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee.

Background: Osteonecrosis is a debilitating complication in children and adolescents with acute lymphoblastic leukemia or acute lymphoblastic lymphoma (LLy). An objective screening test to identify patients at risk for symptomatic, extensive joint involvement will help manage osteonecrosis.

Methods: We performed a prospective, longitudinal pilot study with whole-joint magnetic resonance imaging (MRI) of shoulders, elbows, hips, knees, ankles, and hindfeet to evaluate the incidence and timing of osteonecrosis involving multiple joints in 15 patients with LLy aged 9-21 years at diagnosis. Read More

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http://dx.doi.org/10.1002/pbc.28336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391358PMC

Single approach to double-channel core decompression and bone grafting with structural bone support for treating osteonecrosis of the femoral head in different stages.

J Orthop Surg Res 2020 May 29;15(1):198. Epub 2020 May 29.

Department of Joint Surgery, Aviation General Hospital, Courtyard 3, Anwai Beiyuan, Chaoyang District, Beijing, China.

Background: We created a novel method-single approach to double-channel core decompression and bone grafting with structural bone support (SDBS)-to treat early-stage osteonecrosis of the femoral head (ONFH) by improving the Phemister technique. This study aimed to evaluate the results of SDBS for early-stage ONFH.

Methods: Altogether, 53 patients (73 hips) were treated using SDBS during 2016-2018. Read More

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http://dx.doi.org/10.1186/s13018-020-01717-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260834PMC

Comparative Analysis between Short Stem and Conventional Femoral Stem in Patients with Osteonecrosis of Femoral Head: Metha Stem and Excia Stem.

Orthop Surg 2020 Jun 29;12(3):819-826. Epub 2020 May 29.

Department of Orthopaedic Surgery, College of Medicine, Dong-A University, Busan,, South Korea.

Objective: To compare the intraoperative, radiological, and clinical short-term outcomes of cementless total hip arthroplasties (THA) using a short stem (SS) and a conventional femoral stem (CS) in a randomized prospective control study.

Methods: From June 2011 to October 2017, patients who underwent cementless THA for idiopathic osteonecrosis of the femoral head were recruited. Patients had a minimum 2 years of follow-up after the operation. Read More

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http://dx.doi.org/10.1111/os.12684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307223PMC

Larger Acetabular Labrum Is Associated With Hip Dysplasia, Joint Incongruence, and Clinical Symptoms.

Arthroscopy 2020 May 24. Epub 2020 May 24.

Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Purpose: To evaluate the association of labral length with acetabular morphology and clinical symptoms.

Methods: Patients treated at our hip joint clinic between January 2015 and December 2018 were retrospectively enrolled in the study. Our sample included patients who received a diagnosis of one or more of the following: hip labral tear, femoroacetabular impingement (FAI), and developmental dysplasia of the hip. Read More

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http://dx.doi.org/10.1016/j.arthro.2020.05.023DOI Listing

Greater increase in femoral offset with use of collum femoris-preserving stem than Tri-Lock stem in primary total hip arthroplasty.

J Int Med Res 2020 May;48(5):300060520925999

Department of Osteonecrosis and Hip Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China.

Objective: This study was performed to compare the clinical outcomes and performance of the collum femoris-preserving (CFP) stem (Waldemar Link GmbH & Co., Hamburg, Germany) and the Tri-Lock stem (DePuy Orthopaedics, Warsaw, IN, USA) in terms of femoral offset (FO) and leg length reconstruction.

Methods: Clinical and radiographic data of patients who underwent total hip arthroplasty with either a CFP stem or Tri-Lock stem from January 2016 to March 2017 were compared (65 and 57 patients, respectively). Read More

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http://dx.doi.org/10.1177/0300060520925999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273761PMC

Diagnosis of Osteonecrosis of the Femoral Head: Too Little, Too Late, and Independent of Etiology.

J Arthroplasty 2020 May 5. Epub 2020 May 5.

Department of Orthopaedic Surgery, Stanford University Medical Center Outpatient Center, Redwood City, CA.

Background: Joint preservation is more effective in early-stage osteonecrosis of the femoral head (ONFH); thus, prompt diagnosis when the femoral head is still salvageable is important. We report a 20-year retrospective study that summarizes age at presentation, etiology, and Association Research Circulation Osseous stage at diagnosis.

Methods: Our database was reviewed to identify patients younger than 65 years of age who were diagnosed with atraumatic ONFH between 1998 and 2018. Read More

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http://dx.doi.org/10.1016/j.arth.2020.04.092DOI Listing
May 2020
2.666 Impact Factor

Modified trapdoor procedures using autogenous tricortical iliac graft without preserving the broken cartilage for treatment of osteonecrosis of the femoral head: a prospective cohort study with historical controls.

J Orthop Surg Res 2020 May 24;15(1):183. Epub 2020 May 24.

Department of Orthopedic Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou City, 221002, Jiangsu Province, China.

Background: The aim of the present study was to investigate clinical and radiological outcomes of autologous tricortical iliac grafting performed through a window created at the femoral head without suturing the opened articular cartilage for the treatment of osteonecrosis of the femoral head (ONFH), called modified trapdoor procedures.

Materials And Methods: A total of 59 consecutive patients (67 hips; 36 males and 23 females) with ONFH were included in this study, which was conducted from April 2009 to March 2012. Patients' age ranged from 27 to 46 years old, with a mean age of 36. Read More

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http://dx.doi.org/10.1186/s13018-020-01691-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245755PMC

Avascular Necrosis of the Hip in Primary Care.

Korean J Fam Med 2020 May 25. Epub 2020 May 25.

Department of Orthopaedics, Faculty of Medicine, University Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Malaysia.

Avascular necrosis, or osteonecrosis of the femoral head, is a debilitating condition which leads to the destruction of the hip joint due to an interruption in the blood supply to the bony region and is most commonly due to trauma. The case discussed here has been highlighted as it presented as non-traumatic osteonecrosis of the femoral head with an absence of risk factors in a healthy adult male. A 37-year-old male presented with a 4-month history of recurrent left hip pain, which worsened with initiation of movement and weightbearing on the affected side. Read More

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http://dx.doi.org/10.4082/kjfm.19.0021DOI Listing

Efficacy of total hip arthroplasty for the treatment of patients with femoral head avascular necrosis: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2020 May;99(20):e20259

First Ward of Orthopedis Department, First Affiliated Hospital of Jiamusi University.

Background: Femoral head avascular necrosis (FHAN) is a very common condition among elderly population. Previous studies have reported that total hip arthroplasty (THAP) can benefit patients with such condition. However, no study systematically addressed this topic. Read More

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http://dx.doi.org/10.1097/MD.0000000000020259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253497PMC

Comparison of surgical dislocation and impacting bone graft and surgical dislocation and rotational osteotomy for the treatment of ARCO III femoral head necrosis.

Medicine (Baltimore) 2020 May;99(20):e20215

Department of Orthopaedics, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

Hip preserving procedures are still a challenge in late-stage osteonecrosis of femoral head (ONFH) patients. We aimed to compare the clinical outcomes of surgical dislocation and impaction bone graft and surgical dislocation and rotational osteotomy for treatment of ONFH in Association Research Circulation Osseous (ARCO) stage III patients.We retrospectively reviewed 30 ARCO stage III patients (33 hips) who had surgical dislocation and impaction bone graft or surgical dislocation and rotational osteotomy in our center from June 2012 to December 2017. Read More

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http://dx.doi.org/10.1097/MD.0000000000020215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253930PMC
May 2020
5.723 Impact Factor

Complications after internal screw fixation of nondisplaced femoral neck fractures in elderly patients: A systematic review.

Acta Orthop Traumatol Turc 2020 May;54(3):337-343

Department of Orthopaedics, Hanil General Hospital, Seoul, Korea.

Objective: Internal fixation with cannulated screws for nondisplaced femoral neck fractures in the elderly has substantial reoperation and mortality rates. The selection of either internal fixation or arthroplasty for nondisplaced femoral neck fracture is debatable.

Methods: We performed a systematic review of the literature regarding complications in the internal fixation of nondisplaced femoral neck fractures in elderly (>60 years old) patients. Read More

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http://dx.doi.org/10.5152/j.aott.2020.03.113DOI Listing

History of alendronate.

Bone 2020 Aug 11;137:115411. Epub 2020 May 11.

Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford, UK; Mellanby Centre for Bone Research, University of Sheffield, Sheffield, UK.

Alendronate was synthesized in 1970s in a search for inhibitors of calcification. Istituto Gentili investigators identified it as a potent inhibitor of bone resorption and obtained a patent covering its use in the treatment of osteoporosis and other disorders of excessive bone resorption in the 1980s. Merck licensed alendronate in 1988 and its pharmaceutical chemists reformulated it as a sodium salt with good solubility in a tablet that reduced its potential for esophageal irritation. Read More

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http://dx.doi.org/10.1016/j.bone.2020.115411DOI Listing

Outcomes Following the Urgent Surgical Management of Displaced Femoral Neck Stress Fractures.

J Orthop Trauma 2020 May 8. Epub 2020 May 8.

Naval Medical Center San Diego.

Objectives: To review the clinical course, complication rates, and mid-term functional outcomes associated with the treatment of displaced femoral neck stress fractures (FNSFs) DESIGN:: Retrospective Case Series SETTING:: Military Tertiary Referral Center PATIENTS:: Twenty-one operatively treated displaced FNSFs between 2002 and 2015.

Intervention: Urgent reduction and fixation was performed. If nonunion developed, an intertrochanteric osteotomy was performed. Read More

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http://dx.doi.org/10.1097/BOT.0000000000001810DOI Listing

No Learning Curve of the Direct Superior Approach in Total Hip Arthroplasty.

Orthop Surg 2020 Jun 18;12(3):852-860. Epub 2020 May 18.

Department of Orthopaedic Surgery, Amphia Hospital, Breda, The Netherlands.

Objectives: To assess the learning curve of the direct superior approach (DSA) for total hip arthroplasty (THA) and to compare surgical, clinical, and radiological results with a matched control group using the mini posterior approach (MPA).

Methods: A prospective cohort study was performed from October 2016 to May 2017 including our first 52 patients undergoing THA using the DSA. Patients with primary osteoarthritis or osteonecrosis and a body mass index (BMI) < 35 who were eligible for surgery were included. Read More

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http://dx.doi.org/10.1111/os.12689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307249PMC

A rare case of an irreducible Pipkin II fracture-dislocation of the femoral head in a young patient following low-energy trauma.

Int J Surg Case Rep 2020 7;70:234-237. Epub 2020 May 7.

Service de Traumatologie, CHRU Cavale Blanche, Brest, France. Electronic address:

Introduction: Fractures-dislocations of the femoral head are rare, and irreducible dislocations are even rarer. The functional prognosis is poor.

Presentation Of Case: We report the case of a 23-year-old male brought to the emergency room following low-energy trauma. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231814PMC

Autologous grafts in the treatment of avascular osteonecrosis of the femoral head.

Acta Biomed 2020 May 11;91(2):342-349. Epub 2020 May 11.

ASL TO5.

Background: Osteonecrosis of the femoral head (ONFH) is a frequent orthopedic disease leading to destruction of the hip joint and disabling arthritis. Several procedures have been developed to treat the joint deterioration in case of osteonecrosis, trying to avoid or delay an intervention of total hip replacement, especially in young patients. The aim of this study was to analyze the use of autologous bone micrografts derived from cancellous bone in the management of avascular ONFH. Read More

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http://dx.doi.org/10.23750/abm.v91i2.8188DOI Listing

Total hip replacement using MINIMA short stem: A short-term follow-up study.

World J Orthop 2020 Apr 18;11(4):232-242. Epub 2020 Apr 18.

Orthopaedic Department, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.

Background: Total hip replacement has become one of the most successful orthopaedic procedures. The length of the femoral stem constitutes one of the most important geometrical and mechanical features of the prosthesis. Several different implants are currently available but data are limited concerning the clinical results for some of these implants. Read More

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http://dx.doi.org/10.5312/wjo.v11.i4.232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206196PMC