6,009 results match your criteria Osteonecrosis Hip


An exploratory study of articular cartilage and subchondral bone reconstruction with bone marrow mesenchymal stem cells combined with porous tantalum/Bio-Gide collagen membrane in osteonecrosis of the femoral head.

Mater Sci Eng C Mater Biol Appl 2019 Jun 19;99:1123-1132. Epub 2019 Feb 19.

Department of Orthopedics, Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Dalian, Liaoning, China; Department of Biomedical Engineering, Faculty of Electronic Information and Electrical Engineering, Dalian University of Technology, Linggong Road, Dalian, China. Electronic address:

Osteonecrosis of the femoral head (ONFH) results in collapse of the femoral head and rapid destruction of the hip joint. The repair of post-collapse articular cartilage and subchondral bone is challenging. We interrupted the blood supply to the femoral head and established a full-thickness articular defect animal model after ONFH was determined via X-ray. Read More

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http://dx.doi.org/10.1016/j.msec.2019.02.072DOI Listing

Epidemiology and Perioperative Complications in Patients With Sickle Cell Disease After Orthopaedic Surgery: 26 Years' Experience at a Major Academic Center.

J Am Acad Orthop Surg 2019 Mar 11. Epub 2019 Mar 11.

From the Department of Orthopaedic Surgery (Mr. Cusano, Ms. Curry, Dr. Kingston, Dr. Li), Boston University School of Medicine, and the Center of Excellence in Sickle Cell Disease (Dr. Klings), Boston University School of Medicine, Boston, MA.

Introduction: Surgical management of patients with sickle cell disease (SCD) poses a unique challenge to orthopaedic surgeons due to increased operative and perioperative risk. Studies evaluating perioperative complications among patients with SCD undergoing orthopaedic surgery have been limited. We sought to review the clinical characteristics and perioperative complications in our patients with SCD who required orthopaedic surgery. Read More

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http://dx.doi.org/10.5435/JAAOS-D-18-00288DOI Listing

Treatment of osteonecrosis of the femoral head by core decompression and implantation of fully functional ex vivo-expanded bone marrow-derived mesenchymal stem cells: a proof-of-concept study.

Stem Cells Cloning 2019 1;12:11-16. Epub 2019 Mar 1.

Centro de Terapia Regenerativa Celular, Clínica Las Condes, Santiago, Chile,

Background: Based on several attributes involved in bone formation, bone marrow-resident mesenchymal stem cells (MSCs) have been employed in the treatment of patients suffering from femoral head osteonecrosis. Due to the low content of MSCs in the bone marrow, ex vivo expansion procedures are utilized to increase the cell number. Customarily, before administration of the resulting expanded cell product MSCs to the patient, its cellular identity is usually evaluated according to a set of "minimal phenotypic" markers, which are not modified by ex vivo processing. Read More

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http://dx.doi.org/10.2147/SCCAA.S181883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402444PMC

Efficacy and safety of denosumab compared to bisphosphonates in improving bone strength in postmenopausal osteoporosis: a systematic review.

Singapore Med J 2019 Mar 11. Epub 2019 Mar 11.

Department of Infectious Diseases, Singapore General Hospital, Singapore.

Introduction: Osteoporosis is the main cause of fractures among women after menopause. This study aimed to evaluate the efficacy and safety of denosumab compared to bisphosphonates in treating postmenopausal osteoporosis.

Methods: Databases including PubMed and the Cochrane Central Register of Controlled Trials were systematically searched for randomised controlled trials (RCTs) that directly compared denosumab and bisphosphonates. Read More

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http://dx.doi.org/10.11622/smedj.2019028DOI Listing
March 2019
1 Read

Osteonecrosis of the Femoral Head.

Orthop Clin North Am 2019 Apr 12;50(2):139-149. Epub 2019 Feb 12.

Department of Orthopedic Surgery, University of Virginia, University of Virginia School of Medicine, 400 Ray C. Hunt Drive, #300, Charlottesville, VA 22903, USA. Electronic address:

Osteonecrosis of the femoral head most commonly arises from trauma or corticosteroid and alcohol use but is also associated with blood dyscrasias and metabolic and coagulation disorders. Initial evaluation includes a history and physical examination and plain radiographs. Early-stage osteonecrosis is best evaluated by MRI. Read More

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http://dx.doi.org/10.1016/j.ocl.2018.10.001DOI Listing
April 2019
1 Read

Plasma C-terminal cross-linking telopeptide of type II collagen as a biomarker in advanced stages of femoral head osteonecrosis.

Biomed Pharmacother 2019 Mar 15;111:1213-1220. Epub 2019 Jan 15.

Hip preserving ward, No. 3 Orthopaedic region, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, PR China; Institute of hip joint, Guangzhou University of Chinese Medicine, Guangzhou, PR China. Electronic address:

Aim: The aim of this study is to investigate the potential role of C-terminal cross-linking telopeptide of type II collagen (CTX-II) in the development of femoral head osteonecrosis (FHN).Materials and methodsOne hundred and thirty-two patients diagnosed with FHN and 66 age- and sex-matched healthy subjects were included in this cross-sectional case-control study between May 2016 and November 2016. Bone histomorphology, cartilaginous immunohistochemistry, Western blotting, and level of plasma CTX-II, as well as the receiver operating characteristic (ROC) curve, were evaluated. Read More

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http://dx.doi.org/10.1016/j.biopha.2019.01.013DOI Listing
March 2019
1 Read

Resection arthroplasty in radiation-induced osteonecrosis of the hip.

J Clin Orthop Trauma 2019 Mar-Apr;10(2):364-367. Epub 2018 Feb 24.

Department of Orthopedic Surgery, Kosin University Gospel Hospital, Busan, Republic of Korea.

Purpose: The purpose of this study was to evaluate the choice of appropriate surgical procedure through follow-up of postoperative results in patients with radiation-induced osteonecrosis of the hip.

Materials And Methods: From January 1990 to December 2010, 25 patients underwent surgery for hip osteonecrosis after pelvic irradiation, for a total of 31 cases. The mean patient age was 61. Read More

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http://dx.doi.org/10.1016/j.jcot.2018.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383166PMC
February 2018
1 Read

Prevalence and natural course of pseudotumours after small-head metal-on-metal total hip arthroplasty: a minimum 18-year follow-up study of a previous report.

Bone Joint J 2019 03;101-B(3):317-324

Department of Orthopedic Surgery, Hanyang University Guri Hospital, Guri, South Korea.

Aims: The present study investigated the five-year interval changes in pseudotumours and measured serum metal ions at long-term follow-up of a previous report of 28 mm diameter metal-on-metal (MoM) total hip arthroplasty (THA).

Patients And Methods: A total of 72 patients (mean age 46.6 years (37 to 55); 43 men, 29 women; 91 hips) who underwent cementless primary MoM THA with a 28 mm modular head were included. Read More

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http://dx.doi.org/10.1302/0301-620X.101B3.BJJ-2018-1054.R1DOI Listing
March 2019
2 Reads

Effect of leg-length discrepancy following total hip arthroplasty on collapse of the contralateral hip in bilateral non-traumatic osteonecrosis of the femoral head.

Bone Joint J 2019 Mar;101-B(3):303-310

Department of Orthopaedic Surgery, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea.

Aims: The purpose of this study was to examine whether leg-length discrepancy (LLD) following unilateral total hip arthroplasty (THA) affects the incidence of contralateral head collapse and subsequent THA in patients with bilateral osteonecrosis, and to determine factors associated with subsequent collapse.

Patients And Methods: We identified 121 patients with bilateral non-traumatic osteonecrosis who underwent THA between 2003 and 2011 to treat a symptomatic hip, and who also exhibited medium-to-large lesions (necrotic area ≥ 30%) in an otherwise asymptomatic non-operated hip. Of the 121 patients, 71 were male (59%) and 50 were female (41%), with a mean age of 51 years (19 to 71) at the time of initial THA. Read More

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http://dx.doi.org/10.1302/0301-620X.101B3.BJJ-2018-1053.R1DOI Listing

Spica MRI predictors for epiphyseal osteonecrosis after closed reduction treatment of dysplasia of the hip.

J Pediatr Orthop B 2019 Feb 22. Epub 2019 Feb 22.

Baylor College of Medicine.

Spica MRI with intravenous gadolinium contrast after closed reduction for developmental dysplasia of the hip (DDH) helps to determine successful reduction and attempts to identify patients at risk for epiphyseal osteonecrosis. The objective of our study was to evaluate spica MRI predictors for epiphyseal osteonecrosis after closed reduction. Retrospective study for all patients undergoing closed reduction for DDH followed by gadolinium-enhanced spica MRI between July 2011 and November 2014. Read More

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http://dx.doi.org/10.1097/BPB.0000000000000606DOI Listing
February 2019
2 Reads

Does Extracorporeal Irradiation and Reimplantation After Acetabular Resections Result in Adequate Hip Function? A Preliminary Report.

Clin Orthop Relat Res 2018 Sep;476(9):1738-1748

M. G. Agarwal, M. K. Gundavda, R. Reddy Orthopedic Oncology, P. D. Hinduja Hospital and Medical Research Center, Mumbai, India R. Gupta Orthopedic Oncology, Fortis Hospital, Mohali, India.

Background: Pelvic resections are challenging, and reconstruction of the resected acetabulum to restore mobility and stability is even more difficult. Extracorporeal radiation therapy (ECRT or extracorporeal irradiation) of autograft bone and reimplantation allows for a perfect size match and has been used with some success in the extremities. Although the risk of wound complications in pelvic surgery has discouraged surgeons from using ECRT of autografts in that anatomic site, we believe it may be a reasonable option. Read More

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http://dx.doi.org/10.1007/s11999.0000000000000103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259792PMC
September 2018
1 Read

Corticosteroid dose increase is a risk factor for nonalcoholic fatty liver disease and contralateral osteonecrosis of the femoral head: a case report.

BMC Musculoskelet Disord 2019 Feb 19;20(1):88. Epub 2019 Feb 19.

Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15 Nishi-7, Kita-ku, Sapporo, 060-8638, Japan.

Background: The incidence of bilateral corticosteroid-induced osteonecrosis of the femoral head (ONFH) is high. Although the precise mechanism of corticosteroid-induced ONFH development is unclear, hepatic enzyme abnormalities such as low activity of hepatic cytochrome P450 3A could be one cause. Herein, we report the case of a patient who developed ONFH in the contralateral hip after the dose of corticosteroids for idiopathic thrombocytopenic purpura was increased. Read More

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http://dx.doi.org/10.1186/s12891-019-2468-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381694PMC
February 2019
2 Reads

Differences in magnetic resonance findings between symptomatic and asymptomatic pre-collapse osteonecrosis of the femoral head.

Eur J Radiol 2019 Mar 4;112:1-6. Epub 2019 Jan 4.

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. Electronic address:

Purpose: The purpose of this study was to assess the differences in magnetic resonance (MR) findings between the symptomatic and asymptomatic pre-collapse stage of osteonecrosis of the femoral head (ONFH).

Materials And Methods: This study reviewed 123 consecutive hips in 91 patients in the pre-collapse stage of ONFH based on plain radiographic findings. These 123 hips were divided into symptomatic and asymptomatic groups according to the pain domain score in the Harris hip score system. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.002DOI Listing
March 2019
1 Read

Safety and effectiveness of monthly intravenous ibandronate injections in a prospective, postmarketing, and observational study in Japanese patients with osteoporosis.

Osteoporos Sarcopenia 2018 Mar 17;4(1):22-28. Epub 2018 Feb 17.

Drug Safety Division, Chugai Pharmaceutical Co., Ltd., Tokyo, Japan.

Objectives: This postmarketing, observational study evaluated the safety and effectiveness of monthly intravenous (IV) ibandronate in Japanese patients with osteoporosis.

Methods: Eligible patients received monthly IV ibandronate 1 mg for 12 months. Adverse drug reactions (ADRs) were evaluated. Read More

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http://dx.doi.org/10.1016/j.afos.2018.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362972PMC
March 2018
1 Read

Bilateral osteonecrosis of the hip in panhypopituitarism.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

Osteonecrosis, also known as avascular necrosis, is a condition that causes significant morbidity and loss of function. It is a common complication seen with supraphysiological steroid use. Early diagnosis is critical as it impacts prognosis. Read More

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http://dx.doi.org/10.1136/bcr-2018-227471DOI Listing
February 2019
11 Reads

Closed Reduction for Developmental Dysplasia of the Hip: Early-term Results From a Prospective, Multicenter Cohort.

J Pediatr Orthop 2019 Mar;39(3):111-118

Arnold Palmer Medical Center, Orlando, FL.

Background: Closed reduction (CR) is a common treatment for infantile developmental dysplasia of the hip. The purpose of this observational, prospective, multicenter study was to determine the early outcomes following CR.

Methods: Prospectively collected data from an international multicenter study group was analyzed for patients treated from 2010 to 2014. Read More

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http://dx.doi.org/10.1097/BPO.0000000000000895DOI Listing
March 2019
2 Reads

Cementless 3D Printed Highly Porous Titanium-Coated Baseplate Total Knee Arthroplasty: Survivorship and Outcomes at 2-Year Minimum Follow-Up.

J Knee Surg 2019 Feb 6. Epub 2019 Feb 6.

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.

Newer generation cementless total knee arthroplasty (TKA) implants continue to develop with demonstrated clinical success in multiple recent reports. The purpose of this study was to investigate (1) survivorship, (2) complications, and (3) clinical outcomes of a newer generation cementless and highly porous titanium-coated base plate manufactured using three-dimensional (3D) printing technology. We reviewed a single-surgeon, longitudinally maintained database of patients who underwent primary TKA using cementless, highly porous titanium-coated base plate implants from July 1, 2013 to December 31, 2016. Read More

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http://dx.doi.org/10.1055/s-0039-1677842DOI Listing
February 2019
2 Reads

High rate of reoperation and conversion to total hip arthroplasty after internal fixation of young femoral neck fractures: a population-based study of 796 patients.

Acta Orthop 2019 Feb;90(1):21-25

c Department of Orthopaedics , University of Maryland, R Adams Cowley Shock Trauma Center , Baltimore , MD , USA.

Background and purpose - Most often, the goal of non-geriatric femoral neck fracture surgery is to preserve the native hip joint. However, reoperations for painful implants, osteonecrosis, and nonunion are common. We determined the reoperation rate and time-to-reoperation following internal fixation of these fractures in a large population cohort. Read More

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http://dx.doi.org/10.1080/17453674.2018.1558380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366467PMC
February 2019
1 Read

Magnetic resonance imaging of subchondral insufficiency fractures of the lower limb.

Skeletal Radiol 2019 Jan 31. Epub 2019 Jan 31.

Royal National Orthopaedic Hospital NHS Trust, Stanmore, UK.

Subchondral insufficiency fracture (SIF) is a non-traumatic condition that has historically been associated with elderly, osteoporotic women and patients with systemic conditions. There has been much work done to determine the pathogenesis of SIF, which has previously been regarded as idiopathic, rapid-progressive osteoarthritis or osteonecrosis of the hip, spontaneous osteonecrosis of the knee (SONK), osteochondral defect (OCD) of the talus and adult-onset Freiberg infraction of the metatarsal head. Early diagnosis and management are crucial to prevent subchondral collapse, secondary osteonecrosis and early-onset osteoarthritis. Read More

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http://dx.doi.org/10.1007/s00256-019-3160-4DOI Listing
January 2019
4 Reads

[A mini-incision on the anterior hip for pediatric femur neck fractures of type Delbet Ⅱ].

Zhonghua Wai Ke Za Zhi 2019 Feb;57(2):129-133

Department of Pediatric Orthopaedic, Children's Hospital, Nanjing Medical University, Nanjing 210019, China.

To investigate the early clinical outcomes of hip anterior short incision and open reduction and internal fixation for the treatment of children with Delbet Ⅱ femoral neck fracture. A retrospective analysis of 12 children with DelbetⅡ femoral neck fractures was performed with the anterior short incision approach at Department of Pediatric Orthopaedic, Children's Hospital, Nanjing Medical University from January 2014 to August 2016. There were 7 males and 5 females including 8 cases at left side and 4 cases at right side,aged (11. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5815.2019.02.011DOI Listing
February 2019
6 Reads

The radiological and clinical follow-up of osteonecrosis in cancer patients.

Acta Oncol 2019 Jan 30:1-7. Epub 2019 Jan 30.

f Department of Surgery , Oulu University Hospital , Oulu , Finland.

Background: In patients with cancer, osteonecrosis (ON) lesions can affect multiple sites throughout the skeleton, including the long and short bones and the joints. The aims of this study were to explore the natural course of ON in patients treated for cancer by using radiological classification suitable for multisite ON lesions and to assess correlations between the ON grade and surgical procedures.

Material And Methods: Data were retrieved from hospital databases on 233 ON lesions in 54 patients (aged 2-73 years at cancer diagnosis; mean age: 25 years). Read More

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https://www.tandfonline.com/doi/full/10.1080/0284186X.2019.1
Publisher Site
http://dx.doi.org/10.1080/0284186X.2019.1566769DOI Listing
January 2019
10 Reads

Volume of hip synovitis detected on contrast-enhanced magnetic resonance imaging is associated with disease severity after collapse in osteonecrosis of the femoral head.

Skeletal Radiol 2019 Jan 29. Epub 2019 Jan 29.

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Objective: To evaluate the relationship between the volume of hip synovitis detected on contrast-enhanced magnetic resonance imaging (MRI) and the disease stage of osteonecrosis of the femoral head (ONFH).

Materials And Methods: Sixty-three consecutive hips in 40 ONFH patients were reviewed using contrast-enhanced MRI. Ten unaffected hips in 10 patients with unilateral ONFH were used as controls. Read More

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http://dx.doi.org/10.1007/s00256-019-3158-yDOI Listing
January 2019
1 Read

The expression of chondrogenesis-related and arthritis-related genes in human ONFH cartilage with different Ficat stages.

PeerJ 2019 16;7:e6306. Epub 2019 Jan 16.

Department of Orthopedics, The Second Hospital of Jilin University, Changchun, Jilin, China.

Background: It has been well known that the degeneration of hip articular cartilage with osteonecrosis of the femoral head (ONFH) increases the instability of hip and accelerates the development process of ONFH. A better understanding of the expression of chondrogenesis-related and arthritis-related genes of cartilage along with the progression of ONFH seems to be essential for further insight into the molecular mechanisms of ONFH pathogenesis.

Methods: We analyzed the differentially expressed gene profile (GSE74089) of human hip articular cartilage with ONFH. Read More

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http://dx.doi.org/10.7717/peerj.6306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339479PMC
January 2019
2 Reads

Effects of Zoledronic Acid and Vitamin E on Surgical- Induced Osteonecrosis of the Femoral Head in Rabbit.

Arch Bone Jt Surg 2018 Nov;6(6):547-553

Research performed at Shaheed Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Background: Femoral head osteonecrosis is a progressive disease with disabling outcomes in hip joint if not treated. This study was designed to compare the effects of zoledronic acid plus vitamin E versus zoledronic acid alone in surgical induced femoral head osteonecrosis in rabbits.

Methods: 26 Japanese white adult normal male rabbits at 28-32 weeks old were undertaken surgical femoral dislocation to devastate the femoral neck vessels; the femoral neck vessels were ligated and the hip was relocated. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310187PMC
November 2018
2 Reads

Prevalence of CAM deformity and its influence on therapy success in patients with osteonecrosis of the femoral head.

J Tissue Eng Regen Med 2019 Jan 13. Epub 2019 Jan 13.

Department of Orthopaedics and Traumatology, University of Duisburg-Essen, Essen, Germany.

Osteonecrosis of the femoral head (ONFH) and CAM-type femoroacetabular impingement (FAI) present two different pathologies of the hip joint. The aim of this study is to describe the prevalence of CAM-FAI in a collective of ONFH hips and to evaluate its influence on ONFH therapy outcome. A cohort of 86 ONFH hips with a mean follow-up of 46. Read More

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http://dx.doi.org/10.1002/term.2794DOI Listing
January 2019
1 Read

Epidemiology of osteonecrosis among older adults in Sweden.

Osteoporos Int 2019 Jan 9. Epub 2019 Jan 9.

Department of Community Medicine and Rehabilitation, Unit of Geriatric Medicine, Umeå University, 90187, Umeå, Sweden.

This study estimated the incidence of osteonecrosis in a Swedish, nationwide cohort of older adults. Osteonecrosis was approximately 10 times more common than in previous studies. The strongest risk factors were dialysis, hip fracture, osteomyelitis, and organ transplantation, but only hip fractures could have contributed substantially to the disease burden. Read More

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http://dx.doi.org/10.1007/s00198-018-04826-2DOI Listing
January 2019
1 Read

Lateral rim mesh in primary total hip arthroplasty: a suitable option to reconstruct segmental acetabular bone defects in young patients?

Bone Joint J 2019 01;101-B(1):96-103

Department of Orthopaedics, Radboud University Medical Center, Nijmegen, The Netherlands.

Aims: The aim of this study was to analyze the effect of a lateral rim mesh on the survival of primary total hip arthroplasty (THA) in young patients, aged 50 years or younger.

Patients And Methods: We compared a study group of 235 patients (257 hips) who received a primary THA with the use of impaction bone grafting (IBG) with an additional lateral rim mesh with a group of 306 patients (343 hips) who received IBG in the absence of a lateral rim mesh during the same period from 1988 to 2015. In the mesh group, there were 74 male and 183 female patients, with a mean age of 35 years (13 to 50). Read More

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http://dx.doi.org/10.1302/0301-620X.101B1.BJJ-2018-0561.R2DOI Listing
January 2019
3 Reads

[Treatment of avascular necrosis of femoral head in patients with human immunodeficiency virus infection by cementless total hip arthroplasty].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 Dec;32(12):1507-1511

Department of Orthopaedics, the First Affiliated Hospital of Kunming Medical University, Kunming Yunnan, 650000, P.R.China.

Objective: To investigate the effectiveness of cementless total hip arthroplasty (THA) in treatment of avascular necrosis of the femoral head (ANFH) in patients with human immunodeficiency virus (HIV) infection.

Methods: The clinical data of 22 patients (35 hips) with HIV infection and ANFH (positive group), who were treated with cementless THA between February 2014 and January 2017, was retrospectively analyzed. Tirty-three cases (43 hips) without HIV infection, who were treated with cementless THA during the same period, were collected as control (negative group). Read More

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http://dx.doi.org/10.7507/1002-1892.201806126DOI Listing
December 2018
3 Reads

Rapidly progressive hip disease-A rare entity in Korean population.

Int J Surg Case Rep 2018 24;53:486-489. Epub 2018 Nov 24.

Department of Orthopaedics, Bharati Hospital, Pune, 411043, India. Electronic address:

Introduction: The pathophysiology of rapidly progressive hip disease is still unclear. It is a rare subset of osteoarthritis that mainly affects elderly women and presents with new- onset severe hip pain and dysfunction. It is assumed to be triggered by extremely rapid osteoarthritic changes resulting in impaction of the femoral head into the acetabulum, with successive osteonecrosis and insufficiency of the femoral head. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.11.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279998PMC
November 2018
3 Reads

Clinical characteristics of avascular necrosis in patients with Behçet disease: a case series and literature review.

Rheumatol Int 2019 Jan 17;39(1):153-159. Epub 2018 Dec 17.

Division of Rheumatology, Department of Internal Medicine, Gazi University Faculty of Medicine, 06100, Ankara, Turkey.

Avascular necrosis (AVN), also known as osteonecrosis, is characterized by death of the osteocytes due to inadequate blood supply caused by various mechanisms. The hip is the most common affected joint followed by knee. Incidence of AVN in rheumatic diseases is variable and high corticosteroid (CS) therapy is a known major risk factor for development of AVN. Read More

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http://link.springer.com/10.1007/s00296-018-4224-9
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http://dx.doi.org/10.1007/s00296-018-4224-9DOI Listing
January 2019
5 Reads

Long-term hip survival and factors influencing patient-reported outcomes after transtrochanteric anterior rotational osteotomy for osteonecrosis of the femoral head: A minimum 10-year follow-up case series.

Mod Rheumatol 2018 Dec 17:1-7. Epub 2018 Dec 17.

a Department of Orthopaedic Surgery, Graduate School of Medical Sciences , Kyushu University , Fukuoka , Japan.

Objectives: This retrospective study aimed to assess long-term hip survival after transtrochanteric anterior rotational osteotomy (ARO) for osteonecrosis of the femoral head (ONFH) and identify factors influencing patient-reported outcome measures (PROMs) in patients with preserved joints.

Methods: Altogether, 95 consecutive hips in 85 ONFH patients who underwent ARO during 2000-2007 (86.7% follow-up) were studied. Read More

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http://dx.doi.org/10.1080/14397595.2018.1558917DOI Listing
December 2018
2 Reads

Transtrochanteric rotational osteotomy for various hip disorders.

J Orthop Sci 2018 Dec 13. Epub 2018 Dec 13.

Department of Orthopaedic Surgery, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

Background: Joint-preserving procedures should be considered as much as possible for hip disorders in pediatric and young patients. However, in patients with extensive osteonecrosis (ON) of the femoral head combined with severe collapse and advanced secondary osteoarthritis (OA), the optimal procedure has not been elucidated. This retrospective study aimed to investigate the postoperative outcomes of 11 patients who underwent transtrochanteric rotational osteotomy (TRO) alone or with a combination treatment for various hip disorders in young patients and to evaluate the usefulness of TRO. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09492658183033
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http://dx.doi.org/10.1016/j.jos.2018.10.026DOI Listing
December 2018
10 Reads

Incidence of osteonecrosis and insufficiency fracture of the hip and knee joints based on MRI in 300 renal transplant patients.

Hip Int 2018 Nov 1:1120700018808693. Epub 2018 Nov 1.

1 Department of Orthopaedic Surgery, Tokyo Women's Medical University, Tokyo, Japan.

Introduction:: The purpose of this study was to investigate the incidence of necrosis and insufficiency fracture of the hip and knee using magnetic resonance imaging (MRI) in renal transplant patients.

Methods:: We examined 300 consecutive renal transplant patients using MRI of the hips and knees (T1-weighted coronal MRI) preoperatively and at 3 and 6 months postoperatively. Oblique axial-plane T1-weighted MRI and short-tau inversion-recovery T2-weighted MRI were performed parallel to the femoral neck when distinguishing the osteonecrosis of the femoral head (ONFH) from subchondral insufficiency fracture (SIF) of the femoral head was difficult. Read More

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http://dx.doi.org/10.1177/1120700018808693DOI Listing
November 2018
2 Reads

Letter to editor concerning the article "muscle pedicle bone grafting using the anterior one-third of the gluteus medius attached to the greater trochanter for treatment of Association Research Circulation Osseous stage II osteonecrosis of the femoral head" (Cho KJ et al. International Orthopaedics. doi: 10.1007/s00264-018-3839-5).

Authors:
Ali Parsa

Int Orthop 2019 Feb 13;43(2):501. Epub 2018 Dec 13.

Hip Preservation Surgery Division, Department of Orthopedic Surgery, Massachusetts General Hospital at Harvard Medical School, Cambridge street, # 4, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s00264-018-4258-3DOI Listing
February 2019
1 Read

Immunohistochemical analysis of bone metabolism in osteonecrosis of the femoral head.

Rom J Morphol Embryol 2018 ;59(3):819-824

Department of Medical Informatics and Biostatistics, University of Medicine and Pharmacy of Craiova, Romania; Urodiamed Clinic, Craiova, Romania;

Osteonecrosis of the femoral head occurs because of the suppression of blood circulation. At the level of the area affected by the ischemic phenomenon, there are two types of events, in the first stage there is necrosis of the cellular elements, followed by a reparatory phase of the spongy bone tissue. The objective of the study was the histological and immunohistochemical (IHC) analysis of bone metabolism in the repair phase. Read More

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December 2018
3 Reads

Mid-term results of short stem total hip arthroplasty in patients with osteonecrosis of the femoral head.

Hip Int 2018 Dec 11:1120700018816011. Epub 2018 Dec 11.

Department of Orthopaedic Surgery, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima Province, Thailand.

Purpose:: To evaluate the clinical and radiographic mid-term results of short-stem total hip arthroplasty (THA) in patients with osteonecrosis of the femoral head (ONFH).

Methods:: We reviewed 83 cases that underwent Metha stem between November 2010 and November 2012. The appearance of bone trabeculae development and radiolucent line were reviewed and HHS was recorded at 6 months postoperatively then yearly to evaluate the clinical results. Read More

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http://dx.doi.org/10.1177/1120700018816011DOI Listing
December 2018
3 Reads

Antiphospholipid score is a novel risk factor for idiopathic osteonecrosis of the femoral head in patients with systemic lupus erythematosus.

Rheumatology (Oxford) 2018 Dec 6. Epub 2018 Dec 6.

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Objectives: Idiopathic osteonecrosis of the femoral head (ION) is a common complication of SLE associated with CS therapy. Although the pathogenesis of ION involves local bone ischaemia favoured by thrombophilia, the involvement of aPL in lupus ION remains to be elucidated. We have previously reported the aPL score (aPL-S) as a quantitative marker of aPL and the development of thrombotic events in autoimmune diseases. Read More

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http://dx.doi.org/10.1093/rheumatology/key365DOI Listing
December 2018
2 Reads

Impact of acetabular reaming depth on reconstruction of rotation center in primary total hip arthroplasty.

BMC Musculoskelet Disord 2018 Nov 30;19(1):425. Epub 2018 Nov 30.

Department of Orthopedics, China-Japan Union Hospital of Jilin University, 126 xiantai street, Changchun, 130033, People's Republic of China.

Purpose: To study the impact of acetabular reaming depth on reconstruction of rotation center (RC) in unilateral primary total hip arthroplasty (UPTHA) and guide individualized preoperative design.

Methods: 200 postoperative standard bilateral hip anteroposterior radiographs after UPTHA were included, which were collected from January, 2013 to June, 2017 in our hospital. Osteonecrosis of femoral head was the only diagnosis in this cohort. Read More

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http://dx.doi.org/10.1186/s12891-018-2336-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267806PMC
November 2018
3 Reads

Bilateral Developmental Dysplasia of the Hip: Does Closed Reduction Have a Role in Management? Outcome of Closed and Open Reduction in 92 Hips.

J Pediatr Orthop 2019 Apr;39(4):e264-e271

Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK.

Background: Bilateral developmental dysplasia of the hip (DDH) is believed to have a worse outcome than unilateral DDH with the optimal treatment unclear. To define indications for treatment we report a retrospective series of 92 hips (46 patients) who underwent closed reduction (CR) and/or open reduction (OR).

Methods: A total of 58 hips in 29 patients underwent attempted CR using our standardized protocol. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001297DOI Listing
April 2019
17 Reads

Is dynamic locking plate superior than other implants for intracapsular hip fracture: A meta-analysis.

Medicine (Baltimore) 2018 Nov;97(47):e13001

Department of Orthopedics, Puai Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China.

Background: We studied the safety and efficacy of dynamic locking plate vs. other implants (cannulated cancellous screws [CCS] or sliding hip screw [SHS]) in patients undergoing intracapsular hip fracture (ICHF).

Methods: We searched Pubmed, Embase, Web of Science, Cochrane library and Google database from inception to March 25, 2018. Read More

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http://dx.doi.org/10.1097/MD.0000000000013001DOI Listing
November 2018
10 Reads

T ρ and T mapping for the determination of articular cartilage denaturalization with osteonecrosis of the femoral head: A prospective controlled trial.

J Magn Reson Imaging 2019 Mar 21;49(3):760-767. Epub 2018 Nov 21.

Orthopedic Department, First Affiliated Hospital of Clinical Medicine of Guangdong Pharmaceutical University, Guangzhou, P.R. China.

Background: In the future, biochemical MRI might provide a valuable noninvasive quantitative analysis of the biochemical composition of cartilage in osteonecrosis of the femoral head (ONFH).

Purpose: To investigate the diagnostic performance of T ρ and T mapping in cartilage denaturalization with ONFH and to determine the correlation between T ρ and T mapping and the Association Research Circulation Osseous (ARCO) stage.

Study Type: Prospective. Read More

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http://dx.doi.org/10.1002/jmri.26267DOI Listing
March 2019
13 Reads

Traumatic Pubic-type Anterior Dislocation of the Hip with an Ipsilateral Greater Trochanter Fracture: Case Report and Review of Literature.

Cureus 2018 Sep 11;10(9):e3287. Epub 2018 Sep 11.

Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, IND.

Due to the inherent stability of the hip joint, hip dislocations constitute a relatively small proportion of all the traumatic dislocations encountered in the emergency department. Among them, the anterior type of hip dislocation is less common than the posterior type of dislocation. Anterior dislocations are usually associated with an injury to other, nearby structures like the acetabulum and femoral head. Read More

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https://www.cureus.com/articles/14606-traumatic-pubic-type-a
Publisher Site
http://dx.doi.org/10.7759/cureus.3287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235655PMC
September 2018
10 Reads

Orthopaedic challenges for mucopolysaccharidoses.

Ital J Pediatr 2018 Nov 16;44(Suppl 2):123. Epub 2018 Nov 16.

Institute for Maternal and Child Health IRCCS Burlo Garofolo, Via dell'Istria, 65, 34137, Trieste, Italy.

Mucopolysaccharidoses (MPS) are a group of diseases characterized by abnormal accumulation of glycosaminoglycans (GAGs). Although there are differences among the various disease types, the osteoarticular system is always involved. The aim of the present study was to establish a framework for MPS-related orthopaedic manifestations and for their treatment. Read More

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https://ijponline.biomedcentral.com/articles/10.1186/s13052-
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http://dx.doi.org/10.1186/s13052-018-0557-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238259PMC
November 2018
9 Reads

The mean ten-year results of metal-on-metal hybrid hip resurfacing arthroplasty.

Bone Joint J 2018 Nov;100-B(11):1424-1433

Joint Replacement Institute at St Vincent Medical Center, Los Angeles, California, USA.

Aims: This study presents the long-term survivorship, risk factors for prosthesis survival, and an assessment of the long-term effects of changes in surgical technique in a large series of patients treated by metal-on-metal (MoM) hip resurfacing arthroplasty (HRA).

Patients And Methods: Between November 1996 and January 2012, 1074 patients (1321 hips) underwent HRA using the Conserve Plus Hip Resurfacing System. There were 787 men (73%) and 287 women (27%) with a mean age of 51 years (14 to 83). Read More

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https://online.boneandjoint.org.uk/doi/10.1302/0301-620X.100
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http://dx.doi.org/10.1302/0301-620X.100B11.BJJ-2017-1459.R2DOI Listing
November 2018
12 Reads

A special superior cortex compressive fracture of femoral neck: Two case reports.

Medicine (Baltimore) 2018 Oct;97(43):e12876

Orthopaedic Center of People's Liberation Army, the Affiliated Southeast Hospital of Xiamen University, Zhangzhou.

Rationale: Garden type I femoral neck fractures are incomplete stable fractures with impaction in valgus fractures that the question of whether there exists Garden type I femoral neck fracture is currently uncertain. There is still disagreement on the existence of the Garden type I fractures.

Patient Concerns: Herein we report 2 cases with the Garden type I femoral neck fractures. Read More

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http://Insights.ovid.com/crossref?an=00005792-201810260-0002
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http://dx.doi.org/10.1097/MD.0000000000012876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221757PMC
October 2018
10 Reads

Autologous bone marrow-derived CD133 cells with core decompression as a novel treatment method for femoral head osteonecrosis: a pilot study.

Cytotherapy 2019 Jan 5;21(1):107-112. Epub 2018 Nov 5.

Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Academic Center for Education, Culture and Research, Tehran, Iran. Electronic address:

Background: Avascular necrosis (AVN) of femoral head is a progressive bone disease due to ischemia of femoral head; patients experience pain and they can not do normal activity. There is not an effective way to treat the cause of this disease. In recent studies, treatment of this disease using pluripotent stem cell-derived mesenchyme is safe and effective, but this method needs more investigation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14653249183064
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http://dx.doi.org/10.1016/j.jcyt.2018.10.005DOI Listing
January 2019
10 Reads

IL6 receptor blockade preserves articular cartilage and increases bone volume following ischemic osteonecrosis in immature mice.

Osteoarthritis Cartilage 2019 Feb 4;27(2):326-335. Epub 2018 Nov 4.

Center for Excellence in Hip Disorders, Texas Scottish Rite Hospital for Children, Dallas, TX 75219, USA; Orthopaedic Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390-8883, USA. Electronic address:

Objective: Juvenile ischemic osteonecrosis (JIO) of the femoral head is one of the most serious hip disorders causing a permanent deformity of the femoral head in childhood. We recently reported that interleukin 6 (IL6) is predominantly increased in the hip synovial fluid of patients with JIO and that articular chondrocytes are primary source of IL6. This study investigated whether an inhibition of IL6 receptor improves cartilage preservation and bone healing in JIO. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10634584183151
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http://dx.doi.org/10.1016/j.joca.2018.10.010DOI Listing
February 2019
19 Reads

Analysis of the long-term efficacy of core decompression with synthetic calcium-sulfate bone grafting on non-traumatic osteonecrosis of the femoral head.

Med Sci (Paris) 2018 Oct 7;34 Focus issue F1:43-46. Epub 2018 Nov 7.

Department of general surgery, 6th affiliated hospital of Wenzhou medical university (Lishui People's Hospital), Lishui Zhejiang province, No.15 Dazhong Road, Liandu district, Lishui 323000 PR China.

Objective: to investigate the safety and long-term efficacy of core decompression with synthetic calcium-sulfate bone grafting on non-traumatic osteonecrosis of the femoral head.

Method: a total of 76 patients with non-traumatic osteonecrosis of the femoral head were admitted to our hospital from February 2012 to November 2014 and included in the study. All the patients were treated by core decompression with synthetic calcium-sulfate bone grafting. Read More

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http://dx.doi.org/10.1051/medsci/201834f108DOI Listing
October 2018
2 Reads