Endocrinol Metab Clin North Am 2021 Jun 28;50(2):193-203. Epub 2021 Apr 28.
Endocrinology and Metabolism Section, Central Virginia Veterans Affairs Health Care System, Richmond, VA, USA; Division of Endocrinology, Virginia Commonwealth University, Richmond, VA, USA. Electronic address:
Bisphosphonates remain a first-line treatment for osteoporosis and decrease vertebral and hip fractures without side effects in most patients. With extended treatment, osteonecrosis of the jaw and atypical femoral fracture occur rarely, but fear of side effects has led to not starting or discontinuing treatment. Atrial fibrillation and uveitis are less appreciated by the general public, but their rare incidence must be recognized. Read More