109 results match your criteria Osteomyelitis Acute Pyogenic

Magnetic resonance imaging of musculoskeletal infections.

Pol J Radiol 2022 5;87:e141-e162. Epub 2022 Mar 5.

Department of Radiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.

Magnetic resonance imaging (MRI) is a powerful imaging modality in the evaluation of musculoskeletal (MSK) soft tissue, joint, and bone infections. It allows prompt diagnosis and assessment of the extent of disease, which permits timely treatment to optimize long-term clinical outcomes. MRI is highly sensitive and specific in detecting the common findings of MSK infections, such as superficial and deep soft tissue oedema, joint, bursal and tendon sheath effusions, lymphadenopathy, bone marrow oedema, erosive bone changes and periostitis, and bone and cartilage destruction and sequestration. Read More

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Acute Primary Epiphyseal Osteomyelitis of Proximal Tibia - A Case Report and Review of the Literature.

J Orthop Case Rep 2021 Dec;11(12):52-56

Department of Orthopaedics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Introduction: Acute pyogenic epiphyseal osteomyelitis is a rare condition, mostly affecting children. This case report discusses the importance of clinical suspicion and the role of adjuncts in the diagnosis of these cases.

Case Presentation: A 12-year-old female presented with pain in the right knee for 1 week and difficulty in walking for 4 days. Read More

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December 2021

The effect of instrumentation staging on patient outcomes in pyogenic vertebral osteomyelitis: A systematic review.

N Am Spine Soc J 2021 Dec 8;8:100083. Epub 2021 Oct 8.

Department of Orthopedic Surgery, Mercy Health-St. Vincent Medical Center, 2409 Cherry St, Suite #10, OH 43608.

Background: Pyogenic vertebral osteomyelitis is a bacterial infection of the vertebral body that is often treatable with antibiotics, but some cases require additional surgical debridement of the infected tissue. Instrumentation is often utilized for stabilization of the spine as part of the surgical treatment, but controversy remains over the relative risks and benefits of acute instrumentation performed simultaneously with debridement versus delayed instrumentation performed days or weeks after debridement. The purpose of this review was to investigate the relative effects of acute and delayed instrumentation in treatment for pyogenic vertebral osteomyelitis on patient outcomes. Read More

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December 2021

Osteoarticular Infections Approached through the Prism of the Pediatric Orthopedist.

Microorganisms 2021 Dec 24;10(1). Epub 2021 Dec 24.

Pediatric Orthopedics Unit, Pediatric Service of Surgery, University Hospitals of Geneva, CH-1211 Geneva, Switzerland.

Nowadays, () is considered as the main bacterial cause of osteoarticular infections (OAI) in children aged less than 48 months. Next to classical acute hematogenous osteomyelitis and septic arthritis, invasive infections can also give rise to atypical osteoarticular infections, such as cellulitis, pyomyositis, bursitis, or tendon sheath infections. Clinically, OAI are usually characterized by a mild clinical presentation and by a modest biologic inflammatory response to infection. Read More

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December 2021

BCG osteomyelitis: tips for diagnosis.

Skeletal Radiol 2022 Aug 19;51(8):1571-1584. Epub 2022 Jan 19.

Department of Radiology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.

Objective: To report the clinical and imaging characteristics of BCG-osteomyelitis, and compare them with those of pyogenic osteomyelitis.

Materials And Methods: Clinical and imaging findings were retrospectively evaluated in 14 children with BCG osteomyelitis, including 3 with Mendelian susceptibility to mycobacterial diseases (MSMD), and in 40 children with pyogenic osteomyelitis, using Fisher exact and Mann-Whitney U tests.

Results: BCG-osteomyelitis was an indolent inflammatory disease of young children (mean age 15. Read More

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Acute osteoarticular infections in children are frequently forgotten multidiscipline emergencies: beyond the technical skills.

EFORT Open Rev 2021 Jul 8;6(7):584-592. Epub 2021 Jul 8.

Division of Paediatric Orthopaedics, Department of Orthopaedic Surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Acute osteoarticular infections (AOI) should be treated as top emergencies. The first few days following the inception of infection are ultra-critical to long-term prognosis.A comprehensive road map for management of childhood AOI is still lacking despite recent advances in microbiology and imaging (magnetic resonance imaging). Read More

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Acute Pyogenic Osteomyelitis of the Pubic Bone in a Patient with Systemic Lupus Erythematosus Mimicking Fracture of the Pubic Bone and Periprosthetic Joint Infection of the Hip.

Case Rep Orthop 2021 20;2021:6665938. Epub 2021 Jun 20.

Queen Elizabeth Hospital, Gateshead Health Foundation NHS Trust, Sheriff Hill, Gateshead NE9 6SX, UK.

Introduction: Pubic bone osteomyelitis is atypical, and the diagnosis is often overlooked. It may present as osteitis pubis, fracture, or noninfectious inflammation of the pubic symphysis. . Read More

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Differential effects of anti-RANKL monoclonal antibody and zoledronic acid on necrotic bone in a murine model of Staphylococcus aureus-induced osteomyelitis.

J Orthop Res 2022 03 28;40(3):614-623. Epub 2021 May 28.

Department of Orthopaedic Surgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Osteomyelitis is characterized by progressive inflammatory bone destruction accompanied by severe pain and disability. However, with the exception of antibiotic therapies, there is no established therapy to protect the bone from infectious osteolysis. The anti-receptor activator of nuclear factor-kB ligand (RANKL) monoclonal antibody (anti-RANKL Ab) is a potential drug based on its proven effectiveness in preventing joint bone erosion in rheumatoid arthritis; however, the efficacy and adverse effects of anti-RANKL Ab in osteomyelitis remain to be investigated. Read More

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[Infections of the spine : Pyogenic spondylodiscitis and implant-associated vertebral osteomyelitis].

Unfallchirurg 2021 Jun 10;124(6):489-504. Epub 2021 May 10.

Klinik und Poliklinik für Unfallchirurgie, Universitätsklinikum Regensburg (UKR), Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Deutschland.

Pyogenic (unspecific) spondylodiscitis and implant-associated vertebral osteomyelitis (IAVO) are important diseases with the risk of neurological and septic complications. An early diagnosis is essential in which magnetic resonance imaging (MRI), histopathology and microbiological identification of the pathogen play key roles. The goals of conservative treatment in uncomplicated spondylodiscitis are antibiotic infection control and pain management. Read More

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[Acute haematogenous osteomyelitis of the pelvis with multifocal pyogenic abscesses in an adult].

Khirurgiia (Mosk) 2021 (2):84-87

Sechenov First Moscow State Medical University, Moscow, Russia.

Acute hematogenous osteomyelitis (AHO) in adults is a rare disease complicating timely diagnosis. Even greater difficulties are observed in case of pelvic bone lesion. The authors report AHO of the pelvis an adult. Read More

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February 2021


Acta Clin Croat 2020 Jun;59(2):368-372

1University Hospital of Foča, Department of Radiology, University of East Sarajevo, Foča, Republika Srpska, Bosnia and Herzegovina; 2Srebrnjak Children's Hospital, Zagreb, Croatia; 3Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.

Acute osteomyelitis is pyogenic infection of the bone and bone marrow. We report a case of successful diagnosis and treatment in a 12-year-old boy with right shoulder joint osteoarthritis. On admission, he was febrile (39. Read More

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Unusual manifestation of Koch's disease: Gradenigo-Lannois syndrome.

BMJ Case Rep 2020 Nov 2;13(11). Epub 2020 Nov 2.

Otorhinolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India.

Gradenigo-Lannois syndrome or petrous apicitis is an uncommon but a morbid complication of otitis media. Traditionally treated by surgery, recent advances in imaging and antibiotics have favoured a more conservative approach. Although pyogenic organisms are the leading aetiological agent, petrous apicitis due to Koch's bacilli is not rare. Read More

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November 2020

Comparison anterior minimally invasive oblique retroperitoneal approach and posterior transpedicular approach for debridement fusion in patients with lumbar vertebral osteomyelitis: A randomized controlled trial protocol.

Medicine (Baltimore) 2020 Oct;99(44):e22990

Department of Orthopedics.

Background: Pyogenic osteomyelitis of the spine usually occurs in patients over 55 years old with acute osteomyelitis. Surgical treatment and fixation can relieve pain, enhance spinal balance and nerve function, so that patients can walk as soon as possible. Different outcomes of surgical methods include anterior minimally invasive oblique retroperitoneal approach (ORA) and posterior transpedicular approach (PTA). Read More

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October 2020

Methicillin-Resistant (MRSA): One Health Perspective Approach to the Bacterium Epidemiology, Virulence Factors, Antibiotic-Resistance, and Zoonotic Impact.

Infect Drug Resist 2020 22;13:3255-3265. Epub 2020 Sep 22.

Fish Diseases and Management, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.

Methicillin-resistant (MRSA) is a major human pathogen and a historically emergent zoonotic pathogen with public health and veterinary importance. In humans, MRSA commonly causes severe infectious diseases, including food poisoning, pyogenic endocarditis, suppurative pneumonia, otitis media, osteomyelitis, and pyogenic infections of the skin, soft tissues. In the horse, MRSA could cause a localized purulent infection and botryomycosis; in cattle and ewe, localized pyogenic infection and severe acute mastitis with marked toxemia; in sheep, abscess disease resembles caseous lymphadenitis caused by anaerobic strains; in dogs and cats, pustular dermatitis and food poisoning; in pig, exudative epidermatitis "greasy pig disease; in birds, MRSA causes bumble-foot. Read More

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September 2020

A Case of Brodie's Abscess With Tibial Erosion and Extravasation Into Surrounding Soft Tissue.

Cureus 2020 Jun 13;12(6):e8592. Epub 2020 Jun 13.

Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, USA.

Atraumatic limb pain and limp is a common pediatric presentation in the emergency department in the United States. In a majority of cases, these presentations are benign. However, in cases where pediatric patients are repeatedly presenting for atraumatic limb pain, further investigation is required. Read More

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Disseminated Following Open-Heart Surgery, the Heater-Cooler Unit Worldwide Outbreak: Case Report and Minireview.

Front Med (Lausanne) 2020 16;7:243. Epub 2020 Jun 16.

Université de Paris, IAME, INSERM, UMR1137, UFR de Médecine, Paris, France.

Invasive cardiovascular infections by associated with open-heart surgery have been reported worldwide since 2013. Here, we report a case of a 61 year old man, without any other particular medical background, who underwent cardiac surgery for replacing part of the ascending aorta by a bio-prosthetic graft. Eighteen months later, the patient was painful at the lower back with fever. Read More

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Infected Schmorl's node: a case report.

BMC Musculoskelet Disord 2020 May 2;21(1):280. Epub 2020 May 2.

Department of Neurosurgery, Nanoori Hospital Gangnam, 731, Eonju-ro, Gangnam-gu, Seoul, 06048, Republic of Korea.

Background: Schmorls node (SN) are mostly asymptomatic and incidental findings on MRI. However, sometimes they present like acute onset low back pain or acute exacerbation of chronic back pain after minor trauma.

Case Presentation: We present rare case of symptomatic infected SN in 67 years female patient presented with complains of low back pain radiating to right buttock. Read More

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Autoinflammatory diseases in childhood, part 1: monogenic syndromes.

Pediatr Radiol 2020 03 17;50(3):415-430. Epub 2020 Feb 17.

Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.

Autoinflammatory diseases constitute a family of disorders defined by aberrant stimulation of inflammatory pathways without involving antigen-directed autoimmunity. They may be divided into monogenic and polygenic types. Monogenic autoinflammatory syndromes are those with identified genetic mutations, such as familial Mediterranean fever, tumor necrosis factor receptor-associated periodic fever syndrome (TRAPS), mevalonate kinase deficiency or hyperimmunoglobulin D syndrome, cryopyrin-associated periodic fever syndromes (CAPS), pyogenic arthritis pyoderma gangrenosum and acne (PAPA) syndrome, interleukin-10 and interleukin-10 receptor deficiencies, adenosine deaminase 2 deficiency and pediatric sarcoidosis. Read More

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High risk clinical characteristics for pyogenic spinal infection in acute neck or back pain: Prospective cohort study.

Am J Emerg Med 2020 03 17;38(3):491-496. Epub 2019 May 17.

Greater San Antonio Emergency Physicians, Methodist Hospital System, San Antonio, TX, United States of America.

Objective: To identify clinical characteristics associated with pyogenic spinal infection among adults presenting to a community emergency department (ED) with neck or back pain. A secondary objective was to describe the frequency of these characteristics among patients with spinal epidural abscess (SEA).

Methods: We conducted a prospective cohort study in a community ED enrolling adults with neck or back pain in whom the ED provider had clinical concern for pyogenic spinal infection. Read More

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Surgery is safe and effective when indicated in the acute phase of hematogenous pyogenic vertebral osteomyelitis.

Infect Dis (Lond) 2019 04 7;51(4):268-276. Epub 2019 Feb 7.

a Service de Médecine Interne, Hôpital Beaujon, Assistance Publique Hôpitaux de Paris , Clichy , France.

Background: The overall benefit of surgical management in the acute phase of hematogenous pyogenic vertebral osteomyelitis remains difficult to evaluate because of the balance between potential functional benefit versus complications of surgery.

Methods: Between 2000 and 2013, in a tertiary care hospital, we analyzed a cohort of patients with hematogenous pyogenic vertebral osteomyelitis treated surgically and compared them to those treated medically. Neurologic deficit (using the ASIA impairment scale) and pain (using the analgesic level required) 4 months later, recurrences and infection-related deaths 12 months later were evaluated. Read More

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In vivo efficacy of tobramycin-loaded synthetic calcium phosphate beads in a rabbit model of staphylococcal osteomyelitis.

Ann Clin Microbiol Antimicrob 2018 Dec 28;17(1):46. Epub 2018 Dec 28.

Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.

Background: Osteomyelitis is an acute or chronic inflammatory process of the bone following infection with pyogenic organisms like Staphylococcus aureus. Tobramycin (TOB) is a promising aminoglycoside antibiotic used to treat various bacterial infections, including S. aureus. Read More

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December 2018

Childhood Pyogenic Osteomyelitis in Abakaliki, South East Nigeria.

Niger J Surg 2018 Jan-Jun;24(1):27-33

Department of Surgery, Ebonyi State University/Federal Teaching Hospital, Abakaliki, Nigeria.

Background: Pyogenic osteomyelitis is an important child health problem in developing countries. It is a one-disease state with a spectrum of pathological features and clinical forms ranging from acute to chronic presentation. Its pattern of presentation varies from and within subregions. Read More

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Obturator Internus Abscess with Ipsilateral Septic Hip Arthritis.

J Coll Physicians Surg Pak 2016 Nov;26(11):144-145

Department of Orthopaedic Surgery, Busan Paik Hospital College of Medicine, Inje University, Busan, Korea.

Obturator internus muscle (OIM) abscess is an uncommon condition often mistaken for bacterial infection of the hip joint. If the OIM abscess is accompanied by a septic hip, it becomes more difficult to make a diagnosis. Surgical drainage of OIM abscess is difficult because it is located at a deep part of the pelvic cavity. Read More

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November 2016

Pyopericardium with Cardiac Tamponade in a Nigerian Child with Acute Osteomyelitis.

J Cardiovasc Echogr 2017 Apr-Jun;27(2):71-73

Department of Surgery, Cardiothoracic Unit, Bayero University/Aminu Kano Teaching Hospital, Kano, Nigeria.

In pyopericardium, pus accumulates in the pericardial space as a result of infection by pyogenic organisms, most common of which are and . These patients are at risk of cardiac tamponade. Apart from pericardiocentesis in the management of these patients, definitive drug treatment may pose a formidable challenge in a setting of coinfection as in patients with tuberculosis who are predisposed to secondary bacterial infections. Read More

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The Usefulness of T1-Weighted Magnetic Resonance Images for Diagnosis of Acute Leukemia Manifesting Musculoskeletal Symptoms prior to Appearance of Peripheral Blood Abnormalities.

Case Rep Pediatr 2016 18;2016:2802596. Epub 2016 Oct 18.

Department of Pediatrics, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuokashimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan.

The patients with acute leukemia occasionally present with musculoskeletal symptoms initially, including bone pain, joint pain, muscular pain, and functional impairment. Without abnormal findings of peripheral blood cell counts or smear, the correct diagnosis tends to be delayed. Magnetic resonance imaging is often performed to examine musculoskeletal abnormalities; it can simultaneously reveal the bone marrow composition with high anatomical resolution and excellent soft tissue contrast. Read More

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October 2016

Invasive liver abscess syndrome predisposed by Klebsiella pneumoniae related prostate abscess in a nondiabetic patient: a case report.

BMC Res Notes 2016 Aug 9;9:395. Epub 2016 Aug 9.

Department of Medicine, Kaohsiung Armed Forces General Hospital, No.2, Zhongzheng 1st Road, Lingya District, Kaohsiung, 802, Taiwan, ROC.

Background: Prostate abscess is usually a complication of acute urinary tract infection. Invasive liver abscess syndrome is characterized with Klebsiella pneumoniae related multiple organ metastasis. Concomitant pyogenic liver abscess and prostate abscess have rarely been reported. Read More

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Listeria Meningitis in an Immunocompetent Child.

Pediatr Emerg Care 2017 Aug;33(8):579-581

From the *Emergency Department of Paediatrics, Departments of †Clinical Pathology and Microbiology and ‡Hematology and Oncology, and §Infectious Diseases Unit, G. Gaslini Children's Hospital, Genoa, Italy.

Listeria monocytogenes is a facultative anerobic, gram-positive bacillus that is isolated from the soil, vegetables, and wild or domestic animals. Listeria infection is usually found in the older adults, immunocompromised patients, pregnant women, and newborns, whereas it is rare in healthy infants and children. Listeria monocytogenes may cause meningitis, meningoencephalitis, brain abscess, pyogenic arthritis, osteomyelitis, and liver abscess in children. Read More

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Acute Monoarthritis of the Wrist Joint: Tuberculosis or Not?

J Wrist Surg 2016 Mar 15;5(1):77-9. Epub 2015 Dec 15.

Department of Microbiology, Bhopal Memorial Hospital and Research Centre, Bhopal, Madhya Pradesh, India.

Background Extrapulmonary tuberculosis (EPTB) is known to have many and varied presentations. However, isolated involvement of bone with tubercular infection is uncommon. The clinical features of such infections are known to mimic chronic pyogenic osteomyelitis, Brodie abscess, or tumors, but not acute monoarthritis. Read More

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