272 results match your criteria Osteofibrous Dysplasia


Giant monostotic osteofibrous dysplasia of the ilium: A case report and review of literature.

World J Clin Cases 2018 Nov;6(14):830-835

Department of Orthopedics, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215002, Jiangsu Province, China.

Background: Osteofibrous dysplasia (OFD) is a developmental skeletal disorder, and cases with a giant affected area in the pelvis are rare.

Case Summary: In this case report, a 48-year-old man presented with a large tumor in the right iliac region that turned out to be OFD. The patient had rebound tenderness in his right hip. Read More

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November 2018

High-grade squamous cell carcinoma arising in a Tibial Adamantinoma.

Hum Pathol 2018 Nov 26. Epub 2018 Nov 26.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester MN. Electronic address:

Adamantinoma of the long bones is a rare, typically low-grade malignant tumor that frequently involves the tibia. Radiographically, adamantinoma is characteristically a lytic, intracortical and expansile lesion with variable margins. Histologically, adamantinoma is a bimorphic neoplasm, composed of epithelial and osteofibrous elements. Read More

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November 2018

Extraperiosteal segmental excision for osteofibrous dysplasia of tibia with reconstruction by liquid nitrogen-treated recycled autograft.

J Orthop Sci 2018 Oct 30. Epub 2018 Oct 30.

Department of Orthopedics, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, People's Republic of China. Electronic address:

Background: Osteofibrous dysplasia usually progresses until ten years of age and occasionally regresses spontaneously after puberty. Patients with osteofibrous dysplasia usually require close observation. Surgery is an option considered only for extensive, deforming lesions and those with pathological fractures and rapid progression prior to puberty. Read More

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October 2018
3 Reads
1.010 Impact Factor

Clinical-anatomic mapping of the tarsal tunnel with regard to Baxter's neuropathy in recalcitrant heel pain syndrome: part I.

Surg Radiol Anat 2018 Oct 27. Epub 2018 Oct 27.

Department of Anatomy, Histology and Embryology, Division of Clinical and Functional Anatomy, Medical University of Innsbruck, Müllerstr. 59, 6020, Innsbruck, Austria.

Purpose: Neuropathy of the Baxter nerve (BN) seems to be the first cause of the heel pain syndrome (HPS) of neurological origin.

Methods: 41 alcohol-glycerol embalmed feet were dissected. We documented the pattern of the branches of the tibial nerve (TN) and describe all relevant osteofibrous structures. Read More

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October 2018
5 Reads

Adamantinoma of bone: Long-term follow-up of 46 consecutive patients.

J Surg Oncol 2018 Dec 17;118(7):1150-1154. Epub 2018 Oct 17.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.

Background: Adamantinomas are rare bone tumors, commonly affecting the tibia. Due to the rare nature of disease, previous studies are small or from multiple centers. The purpose of this study is to investigate outcomes of patients with adamantinoma treated in a single institution. Read More

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December 2018
3 Reads

Periostin expression in neoplastic and non-neoplastic diseases of bone and joint.

Clin Sarcoma Res 2018 5;8:18. Epub 2018 Sep 5.

1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal and Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, OX3 7HE UK.

Background: Periostin is a matricellular protein that is expressed in bone and joint tissues. To determine the expression of periostin in primary bone tumours and to assess whether it plays a role in tumour progression, we carried out immunohistochemistry and ELISA for periostin in a range of neoplastic and non-neoplastic bone and joint lesions.

Methods: 140 formalin-fixed paraffin-embedded sections of bone tumours and tumour-like lesions were stained by an indirect immunoperoxidase technique with a polyclonal anti-periostin antibody. Read More

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September 2018
3 Reads

Osteofibrous Dysplasia with Rhabdoid Elements in a 38-Year-Old Man with Spontaneous Regression Over Five Years: A Case Report.

JBJS Case Connect 2018 Jul-Sep;8(3):e51

Department of Radiology, Universitaetsklinik Balgrist, Zurich, Switzerland.

Case: A 38-year-old man presented with multifocal, partially confluent osteolytic lesions in the proximal dia-meta-epiphyseal region of the proximal aspect of the left tibia, which had been found incidentally when a radiograph was made after a rotational knee injury. When the results of a percutaneous core needle biopsy proved inconclusive, an open biopsy was performed. Osteofibrous dysplasia (OFD) with scattered groups of plump cells with a rhabdoid phenotype, shown to express both vimentin and pan-cytokeratin, was found. Read More

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July 2018
3 Reads

Optimal Treatment of Osteofibrous Dysplasia of the Tibia.

J Pediatr Orthop 2018 Aug;38(7):e404-e410

Department of Orthopaedic Surgery, Seoul National University Hospital.

Background: Our study of a large patient group reports on the behavior and postoperative recurrence of osteofibrous dysplasia (OFD).

Methods: We reviewed the medical records of 55 patients who were diagnosed with OFD of the tibia and showed typical features of this tumor. The patients' presentation, disease course, history of pathologic fracture, typical radiographic features, surgical treatment history, and surgical results were investigated. Read More

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August 2018
1 Read

Paediatric osteofibrous dysplasia-like adamantinoma with classical radiological findings.

BMJ Case Rep 2018 May 15;2018. Epub 2018 May 15.

Department of Radiology, Alder Hey NHS Foundation Trust, Liverpool, UK.

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May 2018
3 Reads

Osteofibrous Dysplasia of the Tibia in Children: Outcome Without Resection.

J Pediatr Orthop 2017 Dec 8. Epub 2017 Dec 8.

The Hospital for Sick Children, Toronto, ON, Canada.

Background: The proposed association between osteofibrous dysplasia and adamantinoma has led some to advocate resection of the entire lesion, which can require major subsequent reconstruction. However, this link remains unproven and there is some support in more recent literature for a less aggressive approach. This study aims to describe our experience managing pediatric tibial osteofibrous dysplasia with such an approach and to report functional outcomes in children treated thus. Read More

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December 2017
3 Reads

Anatomical etiology of "pseudo-sciatica" from superior cluneal nerve entrapment: a laboratory investigation.

J Pain Res 2017 1;10:2539-2545. Epub 2017 Nov 1.

Department of Anatomy, Tokyo Medical University, Tokyo, Japan.

Objective: The superior cluneal nerve (SCN) may become entrapped where it pierces the thoracolumbar fascia over the iliac crest; this can cause low back pain (LBP) and referred pain radiating into the posterior thigh, calf, and occasionally the foot, producing the condition known as "pseudo-sciatica." Because the SCN was thought to be a cutaneous branch of the lumbar dorsal rami, originating from the dorsal roots of L1-L3, previous anatomical studies failed to explain why SCN causes "pseudo-sciatica". The purpose of the present anatomical study was to better elucidate the anatomy and improve the understanding of "pseudo-sciatica" from SCN entrapment. Read More

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November 2017
15 Reads

Modified technique for preservation of inferior alveolar nerve during mandibulectomy.

Head Neck 2017 12 30;39(12):2562-2566. Epub 2017 Sep 30.

Department of Oral Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, People's Republic of China.

Background: The purpose of this article is to introduce the modified technique of preservation of the inferior alveolar nerve (IAN) during mandibulectomy for a benign lesion.

Methods: Five cases of osteofibrous hyperplasia and 3 cases of centricity osteomyelitis were included. During surgery, the IAN was marked using a planned cutting guide. Read More

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December 2017
13 Reads

The supraorbital region revisited: An anatomic exploration of the neuro-vascular bundle with regard to frontal migraine headache.

J Plast Reconstr Aesthet Surg 2017 Sep 27;70(9):1171-1180. Epub 2017 Jun 27.

Division of Clinical and Functional Anatomy, Department for Anatomy, Histology and Embryology, Medical University of Innsbruck (MUI), Austria. Electronic address:

Background: Recent findings on the pathogenesis of frontal migraine headache support, besides a central vasogenic cause, an alternative peripheral mechanism involving compressed craniofacial nerves. This is further supported by the efficiency of botulinum toxin injections as a new treatment option in frontal migraine headache patients.

Methods: The supraorbital regions of 22 alcohol-glycerine-embalmed facial halves of both sexes were dissected. Read More

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September 2017
10 Reads

Bilateral Tibial Osteofibrous Dysplasia on 18F-FDG PET/CT.

Clin Nucl Med 2017 Aug;42(8):e375-e376

From the Departments of *Radiology, and †Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

A 17-year-old girl had pain in the right front lower leg while road racing 2 months earlier. Radiography and CT showed osteolytic lesions in the medial part of the bilateral tibia. Bone scintigraphy showed focally increased radiotracer uptake in the bilateral tibia. Read More

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August 2017
16 Reads

Sinonasal adamantinoma-like Ewing sarcoma: A case report.

Pathol Res Pract 2017 Apr 2;213(4):422-426. Epub 2016 Dec 2.

Department of Pathology, The Johns Hopkins University School of Medicine, 401 N. Broadway, Weinberg 2249, Baltimore, MD 21231, United States.

We describe the case of a sinonasal adamantinoma-like Ewing sarcoma in a 41-year-old male. Histologically, the tumor exhibited distinctive areas of nested growth pattern with prominent stromal fibrosis and metaplastic bone formation. The tumor cells were small and uniform with minimal amount of pale eosinophilic to clear cytoplasm and round or oval nuclei with finely dispersed chromatin and small nucleoli. Read More

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April 2017
7 Reads

Does osteofibrous dysplasia progress to adamantinoma and how should they be treated?

Bone Joint J 2017 Mar;99-B(3):409-416

Royal Orthopaedic Hospital, Birmingham, UK.

Aims: The aim of this study was to identify any progression between benign osteofibrous dysplasia (OFD), OFD-like adamantinoma and malignant adamantinoma, and to investigate the rates of local recurrence, metastases and survival, in order to develop treatment algorithms for each.

Patients And Methods: A single institution retrospective review of all patients presenting with OFD, OFD-like adamantinoma and adamantinoma between 1973 and 2012 was undertaken. Complete data were available for 73 patients (42 with OFD; ten with an OFD-like adamantinoma and 21 with an adamantinoma). Read More

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March 2017
1 Read

Osteofibrous Dysplasia Versus Ossifying Fibroma: Semantic Confusion.

J Oral Maxillofac Surg 2017 May 24;75(5):885. Epub 2017 Feb 24.

Saitama, Japan.

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May 2017
4 Reads

Management of Large Maxillomandibular Osteofibrous Dysplasia as Part of a Humanitarian Mission.

J Oral Maxillofac Surg 2017 Feb 18;75(2):436.e1-436.e10. Epub 2016 Oct 18.

Maxillofacial Surgeon, Professor and Department Head, Department of Maxillofacial and Plastic Surgery, Caen University Hospital, Caen; UNICAEN, EA4652 Equipe BioConnecT, Caen; Medicine Faculty of Caen, University of Caen Basse Normandie, Caen, France.

Purpose: Maxillomandibular ossifying fibroma is a benign tumor that affects young adults. Complete excision can allow satisfactory management with no recurrence. During a humanitarian mission, one is confronted with many types of damage from these fibromas. Read More

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February 2017
4 Reads

Long-term outcome following treatment of Adamantinoma and Osteofibrous dysplasia of long bones.

Orthop Traumatol Surg Res 2016 11 10;102(7):925-932. Epub 2016 Oct 10.

Department of Orthopedics, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

Introduction: Adamantinoma (AD) is an ultimately rare, low-grade malignant bone tumor. In most cases it occurs in the tibia of young adults. Osteofibrous dysplasia (OFD) is a rare, benign, lesion that is typically seen in children. Read More

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November 2016
1 Read

Radiologic and histological observations in experimental T1-T12 dorsal arthrodesis: A qualitative description of T1-T12 segment and other body parts involved, between prepubertal age and skeletal maturityxs.

Indian J Orthop 2016 Sep;50(5):558-566

Department of Radiology, Research Unit of Paleoradiology and Allied Sciences, University Hospital of Trieste, LTS, 34127 Trieste, Italy.

Background: This experimental study provides a qualitative description and the morpho-structural features of the fusions taking place in the thoracic spine between prepubertal age and skeletal maturity. There is a lack of informations regarding the influence of partial or total dorso-thoracic vertebral arthrodesis on the development of the thoracic cage as well as its potential effects on different intra and extra-thoracic organs. This study admits the hypothesis that vertebral arthrodesis may have influence on other body areas and so, it intends to verify the possible secondary involvement of other body parts, such as intervertebral discs, cervical and thoracic spinal ganglia, sternocostal cartilage, ovaries and lungs. Read More

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September 2016
7 Reads

Osteofibrous dysplasia of clavicle clinically mimicking chronic osteomyelitis.

Indian J Radiol Imaging 2016 Apr-Jun;26(2):290-3

Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, Punjab and Haryana, India.

Osteofibrous dysplasia or ossifying fibroma is an uncommon benign fibro-osseous lesion of childhood, commonly described in the maxilla and the mandible. Among long bones, it usually presents in the tibia as a painless swelling or anterior bowing. Ossifying fibroma of clavicle has never been reported in English literature, to the best of our knowledge. Read More

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July 2016
1 Read

[Tumor-like lesions of bone].

Authors:
R Erlemann G Jundt

Radiologe 2016 Jun;56(6):507-19

Knochentumorreferenzzentrum am Institut für Pathologie, Universitätsspital, Basel, Schweiz.

Historically, tumor-like lesions of bone were defined as non-neoplastic bone lesions. Today, however, some of them are considered real neoplasms. They are among the most frequent bone lesions. Read More

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June 2016
4 Reads

Sclerostin expression in bone tumours and tumour-like lesions.

Histopathology 2016 Sep 8;69(3):470-8. Epub 2016 Apr 8.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Oxford, UK.

Aims: To assess the immunophenotypic and mRNA expression of sclerostin in human skeletal tissues and in a wide range of benign and malignant bone tumours and tumour-like lesions.

Methods And Results: Sclerostin expression was evaluated by immunohistochemistry and quantitative polymerase chain reaction (PCR). In lamellar and woven bone, there was strong sclerostin expression by osteocytes. Read More

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September 2016
6 Reads

Chondroblastic osteosarcoma secondary to fibrosarcoma: A case report and literature review.

Oncol Lett 2015 Dec 12;10(6):3573-3576. Epub 2015 Oct 12.

Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.

Osteosarcoma, which is most common in non-blood systemic tumors, accounts for 20% of primary bone malignancies. Primary osteosarcoma usually occurs in young individuals aged 10-20 years, while secondary osteosarcoma is more common in the elderly. It had been reported that secondary osteosarcoma may be associated with osteofibrous dysplasia, bone infarction, chondrosarcoma or osteogenesis imperfecta. Read More

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December 2015
27 Reads

Outcome of longitudinal versus transverse incision in de Quervain's disease and its implications in Indian population.

Authors:
Kuljit Kumar

Musculoskelet Surg 2016 Apr 8;100(1):49-52. Epub 2015 Dec 8.

Department of Orthopaedics, Kalpana Chawla Government Medical College, Karnal, Haryana, India.

Background: de Quervain's disease is an inadequacy into the first extensor compartment of wrist between the osteofibrous tunnel and the tendons. This mechanical conflict generates a tenosynovitis of the extensor pollicis brevis and the abductor pollicis longus tendons in first dorsal extensor compartment of the wrist.

Aim: (1) To compare the clinical results obtained by longitudinal and transverse incisions and (2) the implication of clinical results in Indian population. Read More

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April 2016
8 Reads

Mutations Preventing Regulated Exon Skipping in MET Cause Osteofibrous Dysplasia.

Am J Hum Genet 2015 Dec;97(6):837-47

Department of Women's and Children's Health, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand.

The periosteum contributes to bone repair and maintenance of cortical bone mass. In contrast to the understanding of bone development within the epiphyseal growth plate, factors that regulate periosteal osteogenesis have not been studied as intensively. Osteofibrous dysplasia (OFD) is a congenital disorder of osteogenesis and is typically sporadic and characterized by radiolucent lesions affecting the cortical bone immediately under the periosteum of the tibia and fibula. Read More

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December 2015
22 Reads

A rare case of pure primary hemangioma of the scapula: A case report.

Oncol Lett 2015 Oct 12;10(4):2265-2268. Epub 2015 Aug 12.

Multidisciplinary Therapy Center of Musculoskeletal Tumor, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.

Hemangioma is a benign vascular tumor, which may occur in any bone of the body. The most common locations are the spine and craniofacial bone; however, occurrence is extremely rare in the scapula. The current study presented the case of a 58-year-old female, with scapula hemangioma in the left shoulder who presented with joint ache that had lasted for ~1 year. Read More

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October 2015
2 Reads

Autologous mesenchymal stem cell (MSCs) transplantation for critical-sized bone defect following a wide excision of osteofibrous dysplasia.

Int J Surg Case Rep 2015 5;17:106-11. Epub 2015 Nov 5.

Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jl. Dipenogoro No. 71, Salemba, Jakarta Pusat 10430, Indonesia.

Introduction: Osteofibrous dysplasia is a rare non-neoplastic disease that is almost exclusive to pediatric tibial diaphysis. Wide excision of the lesion is recommended to avoid recurrence. However, such radical surgery will results in large segmental bone defects that will require further extensive reconstructive surgery. Read More

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January 2016
8 Reads

Osteofibrous Dysplasia-like Adamantinoma of the Tibia in a 15-Year-Old Girl.

Am J Orthop (Belle Mead NJ) 2015 Oct;44(10):E411-3

Department of Orthopedics, Texas Tech University Health Sciences Center, Lubbock, TX.

Osteofibrous dysplasia and adamantinoma are rare lesions of primary benign and malignant bone tumors with an incidence of less than 1%. These lesions arise primarily in long bones with a predilection for the tibia and fibula. Osteofibrous dysplasia is a benign fibro-osseous lesion typically found in children younger than 10 years. Read More

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October 2015
2 Reads

Bone Transport for Reconstruction in Benign Bone Tumors.

Clin Orthop Surg 2015 Jun 18;7(2):248-53. Epub 2015 May 18.

Department of Orthopaedic Surgery, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.

Background: The aim of this study was to assess the results of using the Ilizarov apparatus to transport bones in the treatment of benign bone tumors.

Methods: Seven patients (six males and one female) with benign bone tumors were treated by bone transport with an Ilizarov apparatus at our institution. Their mean age at surgery was 14. Read More

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June 2015
7 Reads

Gruber, Gradenigo, Dorello, and Vail: key personalities in the historical evolution and modern-day understanding of Dorello's canal.

J Neurosurg 2016 Jan 26;124(1):224-33. Epub 2015 Jun 26.

Departments of 1 Neurological Surgery and.

A century ago an ambitious young anatomist in Rome, Primo Dorello, who sought to understand the cause of abducent nerve palsy that often occurred in patients with severe middle ear infections, conducted intricate studies on the intracranial course of the nerve. In his findings, he identified that the abducent nerve passes through a narrow sinus near the apex of the petrous bone, which formed an osteofibrous canal. Dorello suggested that in this enclosed region the abducent nerve may be particularly vulnerable to compression due to the vascular edema accompanying the infection. Read More

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January 2016
8 Reads

Flexor Digitorum Accessorius Longus: Importance of Posterior Ankle Endoscopy.

Case Rep Orthop 2015 28;2015:823107. Epub 2015 Apr 28.

Hospital Quirón Barcelona, Plaça d'Alfonso Comín, 08023 Barcelona, Spain.

Endoscopy for the posterior region of the ankle through two portals is becoming more widespread for the treatment of a large number of conditions which used to be treated with open surgery years ago. The tendon of the flexor hallucis longus (FHL) travels along an osteofibrous tunnel between the posterolateral and posteromedial tubercles of the talus. Chronic inflammation of this tendon may lead to painful stenosing tenosynovitis. Read More

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June 2015
2 Reads

A simple blind tenolysis for flexor carpi radialis tendinopathy.

Hand (N Y) 2015 Jun;10(2):323-7

Department of Surgery, St. Elisabeth Hospital, Hilvarenbeekse Weg 60, 5022 GC Tilburg, The Netherlands.

Background: Flexor carpi radialis (FCR) tendinopathy is an entity with a chronic form (repetitiveness of work) and an acute form (acute overstretching of the wrist). Confirmation of this syndrome can be established by injection of a small amount of a local anesthetic in the sheet of the FCR at this tender point. Complete relieve of the symptoms after injection confirms the existence of a tendinopathy of the FCR. Read More

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June 2015
11 Reads

Osteofibrous dysplasia-like adamantinoma in a 3-month-old male infant: a case report.

Acta Orthop Traumatol Turc 2015 ;49(2):210-2

Memorial Hospital, Department of Orthopedics and Traumatology, İstanbul, Turkey.

We report a case of a very rarely seen osteofibrous dysplasia-like adamantinoma (OFDLA) of the lower leg in a 3-month-old male infant, making it the youngest case in the literature. OFDLA is typically regarded as a benign lesion; however, due to its convertibility into classical adamantinoma, it is recommended to evaluate it as a pre-malignant lesion. After OFDLA diagnosis with biopsy, our case underwent surgical resection and reconstruction with a large allograft. Read More

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February 2016
6 Reads

Effect of denosumab on recurrent giant cell reparative granuloma of the lumbar spine.

Spine (Phila Pa 1976) 2015 May;40(10):E601-8

From the Departments of *Orthopaedic Surgery and †Spinal Surgery and Medical Engineering, Mie University Graduate School of Medicine, Mie, Japan.

Study Design: A case of recurrent giant cell reparative granuloma (GCRG) of the lumbar spine successfully treated with denosumab is reported; a fully human monoclonal antibody against the receptor activator of nuclear factor kappa B (RANK) ligand (RANKL).

Objective: To report the first case of recurrent GCRG of the lumbar spine treated with denosumab.

Summary Of Background Data: GCRG is a non-neoplastic osteofibrous lesion usually found in the maxilla and mandible but rarely in the spine. Read More

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May 2015
8 Reads

Prospective study of superior cluneal nerve disorder as a potential cause of low back pain and leg symptoms.

J Orthop Surg Res 2014 Dec 31;9:139. Epub 2014 Dec 31.

Background: Entrapment of the superior cluneal nerve (SCN) in an osteofibrous tunnel has been reported as a cause of low back pain (LBP). However, there are few reports on the prevalence of SCN disorder and there are several reports only on favorable outcomes of treatment of SCN disorder on LBP. The purposes of this prospective study were to investigate the prevalence of SCN disorder and to characterize clinical manifestations of this clinical entity. Read More

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December 2014
5 Reads

Osteofibrous Dysplasia managed with Extraperiosteal excision, Autologous free fibular graft and bone graft substitute.

J Orthop Case Rep 2015 Jan-Mar;5(1):41-4

Department of Orthopaedics, Mahatma Gandhi Medical College and Research Institute. Sri Balaji Vidyapeeth University, Pondicherry. India.

Introduction: Osteofibrous Dysplasia is a rare benign self-limiting fibro-osseous lesion most commonly seen in the diaphysis of the tibia. Its incidence is reported to be 0.2% of all primary bone tumors. Read More

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June 2016
2 Reads

[Osteolytic diaphyseal tibial lesion with increasing constant dull tibial pain].

Radiologe 2015 Jan;55(1):53-8

Abt. für Diagnostische und Interventionelle Radiologie, Radiologische Klinik, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland,

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January 2015
1 Read

Role of apparent diffusion coefficients with diffusion-weighted magnetic resonance imaging in differentiating between benign and malignant bone tumors.

World J Surg Oncol 2014 Nov 29;12:365. Epub 2014 Nov 29.

Department of Radiology, Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kong Jiang Road, Shanghai 200092, China.

Background: Benign and malignant bone tumors can present similar imaging features. This study aims to evaluate the significance of apparent diffusion coefficients (ADC) in differentiating between benign and malignant bone tumors.

Methods: A total of 187 patients with 198 bone masses underwent diffusion-weighted (DW) magnetic resonance (MR) imaging. Read More

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November 2014
13 Reads

Hemodynamic stroke: A rare pitfall in cranio cervical junction surgery.

J Craniovertebr Junction Spine 2014 Jul;5(3):122-4

Department of Neurosurgery, University Hospital, Heinrich Heine University, Düsseldorf, Germany.

Surgical C1C2-stabilization may be complicated by arterial-arterial embolism or arterial injury. Another potential complication is hemodynamic stroke. The latter might be induced in patients with poor posterior fossa collateralization (risk factor 1) when the vertebral artery (VA) is compressed during reduction (risk factor 2). Read More

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July 2014
1 Read

Benign bone tumors.

Authors:
Robert Steffner

Cancer Treat Res 2014 ;162:31-63

Orthopaedic Oncology, UC Davis Comprehensive Cancer Center, Sacramento, CA, USA,

Benign bone lesions are a broad category that demonstrates a spectrum of activities from latent to aggressive. Differentiating the various tumors is important in order to properly determine necessary intervention. This chapter focuses on the presentation, imaging, diagnostic features, and treatment of the most common benign bone tumors in order to help guide diagnosis and management. Read More

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September 2014
8 Reads

[Delayed lower extremity deep venous thrombosis after operation for osteofibrous dysplasia of the left femur: report of one case].

Zhejiang Da Xue Xue Bao Yi Xue Ban 2014 May;43(3):379-81

IDepartment of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China.

Lower extremity deep venous thrombosis (LDVT) is one of the most common complications in orthopedic surgery, and it often occurs in the first 24 h after operation. We report a case of delayed LDVT, which occurred on d 16 after operation for osteofibrous dysplasia on the left femur. Upon the diagnosis confirmed, thrombolysis and anticoagulation therapy was conducted. Read More

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May 2014
1 Read

Proliferative, reparative, and reactive benign bone lesions that may be confused diagnostically with true osseous neoplasms.

Semin Diagn Pathol 2014 Jan 25;31(1):66-88. Epub 2013 Dec 25.

Department of Pathology, University of Washington Medical Center, Seattle, Washington.

Diagnostic problems attending intraosseous and parosteal pseudoneoplastic lesions can be radiographic, or histological, or both. Proliferations in this category may contain cellular fibro-osseous or chondro-osseous tissues that are difficult to separate microscopically from those seen in various true neoplasms of the bones. This review considers the clinicopathologic features of fibrous dysplasia, benign fibro-osseous lesions of the jawbones, osteofibrous dysplasia, metaphyseal fibrous defect, giant-cell reparative granuloma, "brown tumor" of hyperparathyroidism, synovial chondrometaplasia, aneurysmal bone cyst, tumefactive chronic osteomyelitis, proliferative Paget disease, and polyvinylpyrrolidone storage disease of bone. Read More

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January 2014
3 Reads

Sliding fibular graft repair for the treatment of recurrent peroneal subluxation.

Foot Ankle Int 2014 May 17;35(5):496-503. Epub 2014 Mar 17.

Department of Trauma, Affiliated Hospital of Qingdao University, Qingdao, PR China.

Background: Because recurrent peroneal subluxation can produce functional impairment in athletes, most authors suggest operative intervention for patients who fail nonoperative treatment. The present report introduces the modified sliding fibular graft repair for this pathology.

Methods: This retrospective study was conducted to analyze the clinical results for 26 patients with recurrent peroneal subluxation who underwent this procedure with a follow-up of a minimum of 3 years. Read More

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May 2014
2 Reads

Activating GNAS mutations in parosteal osteosarcoma.

Am J Surg Pathol 2014 Mar;38(3):402-9

Departments of *Laboratory Medicine and Pathology †Radiology, Mayo Clinic, Rochester, MN.

Parosteal osteosarcoma is a surface-based osteosarcoma that often exhibits deceptively bland cytologic features, hindering diagnosis in small biopsies or when correlative radiologic imaging is not readily available. A number of benign and malignant fibro-osseous lesions, including fibrous dysplasia (FD) and low-grade central osteosarcoma, fall within the morphologic differential diagnosis of parosteal osteosarcoma. Somatic mutations in GNAS, encoding the α-subunit of the heterotrimeric G protein complex (Gsα), occur in FD and McCune-Albright syndrome but have not been reported in parosteal osteosarcoma. Read More

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March 2014
6 Reads

MR findings of the osteofibrous dysplasia.

Korean J Radiol 2014 Jan-Feb;15(1):114-22. Epub 2014 Jan 8.

Department of Orthopedic Surgery, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea.

Objective: The aim of this study was to describe MR findings of osteofibrous dysplasia.

Materials And Methods: MR images of 24 pathologically proven osteofibrous dysplasia cases were retrospectively analyzed for a signal intensity of the lesion, presence of intralesional fat signal, internal hypointense band, multilocular appearance, cortical expansion, intramedullary extension, cystic area, cortical breakage and extraosseous extension, abnormal signal from the adjacent bone marrow and soft tissue and patterns of contrast enhancement.

Results: All cases of osteofibrous dysplasia exhibited intermediate signal intensity on T1-weighted images. Read More

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April 2014
5 Reads

Imaging in osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma, and classic adamantinoma.

Clin Radiol 2014 Feb 5;69(2):200-8. Epub 2013 Nov 5.

Department of Radiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK.

Fibro-osseous lesions of the bone are well-recognized primary bone tumours. However, given the degree of overlap of imaging findings and variation in management of various sub-types, it is a widely accepted practice to perform a biopsy to obtain histopathological confirmation of the diagnosis. The following is a summary of the epidemiology, clinicopathological features, and review of the imaging features of fibro-osseous lesions, including osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma, adamantinoma, and lesions that closely mimic them. Read More

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February 2014
2 Reads

The usefulness of ICG video angiography in the surgical treatment of superior cluneal nerve entrapment neuropathy: technical note.

J Neurosurg Spine 2013 Nov 20;19(5):624-8. Epub 2013 Sep 20.

Department of Neurosurgery, Chiba Hokuso Hospital, Nippon Medical School. Chiba, Japan;

Superior cluneal nerve (SCN) entrapment neuropathy is a known cause of low back pain. Although surgical release at the entrapment point of the osteofibrous orifice is effective, intraoperative identification of the thin SCN in thick fat tissue and confirmation of sufficient decompression are difficult. Intraoperative indocyanine green video angiography (ICG-VA) is simple, clearly demonstrates the vascular flow dynamics, and provides real-time information on vascular patency and flow. Read More

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November 2013
7 Reads

Congenital osteofibrous dysplasia Campanacci: spontaneous postbioptic regression.

J Pediatr Hematol Oncol 2014 Apr;36(3):249-52

*Department of Radiology and Sarcoma Center Berlin-Brandenburg, HELIOS Klinikum Berlin-Buch §Institute for Pathology, Reference Center for Orthopedic Pathology, HELIOS Klinikum Emil-von-Behring, Stiftung Oskar-Helene-Heim, Berlin and Sarcoma Center Berlin-Brandenburg, Berlin †Department of Radiology, Klinikum Augsburg, Augsburg ‡Department of Clinical Radiology, Medical University Münster, Münster, Germany.

Osteofibrous dysplasia Campanacci is a rare benign bone tumor most frequently observed in young childhood. The exclusive localization in the tibia is very characteristic. The incidence of congenital primary bone tumors is an absolute rarity. Read More

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April 2014
9 Reads