3,692 results match your criteria Osteochondroma and Osteochondromatosis
J Cutan Aesthet Surg 2018 Jul-Sep;11(3):143-147
Department of Dermatology, Topiwala National Medical College and B. Y. L. Nair Charitable Hospital, Mumbai, Maharashtra, India.
The clinical diagnosis of benign and malignant nail tumors can be difficult. Dermoscopy can provide a clue to the diagnosis but nail biopsy is the gold standard in establishing the diagnosis. Here, we report three cases of rare nail tumors, that is, onychopapilloma, onychomatricoma, and subungual osteochondroma, which were diagnosed on histopathology and managed surgically. Read More
Horm Res Paediatr 2018 Nov 27:1-15. Epub 2018 Nov 27.
Department of Pediatrics, The Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada.
Skeletal abnormalities are common in children and adolescents diagnosed and treated for a malignancy. The spectrum ranges from mild pain to debilitating osteonecrosis and fractures. In this review, we summarize the impact of cancer therapy on the developing skeleton, provide an update on therapeutic strategies for prevention and treatment, and discuss the most recent advances in musculoskeletal research. Read More
Radiol Case Rep 2019 Feb 7;14(2):187-189. Epub 2018 Nov 7.
Gold Coast University Hospital Radiology Department, 1 Hospital Blvd, Southport QLD 4215, Australia.
Osteochondromas are bone exostoses, with the vast majority extending from the metaphyseal region of long bones and are capped by cartilage. A review of the current literature reveals spontaneous regression of osteochondromas is a rarely documented event, with all but two of these recorded events resolving before skeletal maturity and within 6 years of identification. We present a case of trauma-induced resolution of a solitary osteochondroma after less than 3 months in a 15-month-old male, with a review of current literature. Read More
J Shoulder Elbow Surg 2018 Nov;27(11):e348-e353
Department of Orthopaedics, First Faculty of Medicine, Charles University and Military University Hospital Prague, Czech Republic. Electronic address:
Foot (Edinb) 2018 Sep 31;36:55-58. Epub 2018 Jan 31.
İstanbul Medeniyet University Goztepe Training and Research Hospital, Orthopaedics and Traumatology Department, Turkey. Electronic address:
Introduction: Trevor's disease, also known as dyplasia epiphysealis hemimelica, is characterised by osteochondromas arising from epiphyses. The disease typically affects one side of an epiphysis (usually the medial side).
Case Presentation: A case in whom both the medial and lateral sides of the epiphysis were involved is described. Read More
Medicine (Baltimore) 2018 Oct;97(42):e12855
Department of Medical Genetics.
Hereditary multiple osteochondroma (HMO) is one of the most common genetic skeletal disorders. It is caused by mutations in either EXT1 or EXT2 resulting in abnormal skeletal growth and morphogenesis. However, the spectrum and frequency of EXT1 and EXT2 mutations in Chinese patients with HMO was not previously investigated. Read More
Zhongguo Gu Shang 2018 Sep;31(9):871-873
The First Bethune Hospital of Jilin University, Changchun 130000, Jilin, China;
J Orthop Sci 2018 Oct 11. Epub 2018 Oct 11.
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69, Otemae, Chuo-ku, Osaka, 541-8567, Japan. Electronic address:
Rev Port Cir Cardiotorac Vasc 2018 Jan-Jun;25(1-2):103-104
Serviço de Angiologia e Cirurgia Vascular, Centro Hospitalar de São João, Porto, Portugal.
JB JS Open Access 2018 Jun 29;3(2):e0064. Epub 2018 May 29.
Department of Pathology, Institute of Biomedical and Health Sciences, Graduate School of Hiroshima University, Hiroshima, Hiroshima, Japan.
Background: Reported information on the characteristics of benign bone tumors is disjointed, and the long-term trends in the occurrence of malignant bone tumors by histological type have not been reported in Japan. Our aim was to describe the characteristics of both benign and malignant bone tumors as described in cases registered in the Hiroshima Tumor Tissue Registry from 1973 to 2012.
Methods: Cases were identified with the International Classification of Diseases for Oncology (ICD-O-3) topography code C40-C41 (bones, joints, and articular cartilage), and histological types were classified according to the World Health Organization 2013 system. Read More
Int J Spine Surg 2018 Jan 30;12(1):43-48. Epub 2018 Mar 30.
Spine Department, Star Hospitals, Road No. 10, Banjara Hills, Hyderabad, Telangana, India.
Background: Enchondroma protuberans (EP) is rare, benign cartilaginous bone tumor arising from the intramedullary cavity of long bones and usually protrudes beyond the cortex with an exophytic growth pattern resembling osteochondroma. This study reports on a rare case of EP arising from the transverse process of the D8 vertebra and extending to the adjacent 7th and 8th ribs and the paraspinal tissues.
Methods: A 45-year-old female patient came in with complaints of upper back pain radiating up to the left costal margin for the past 6 months. Read More
Radiologia 2018 Sep 28. Epub 2018 Sep 28.
Servicio de Diagnóstico por Imágenes, Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
Sternal tumours are rare in children. The differential diagnoses include a wide spectrum of benign (from bone cyst to osteoblastoma, osteochondroma and fibrous displasia) and malignant tumours (Ewing's sarcoma, chondrosarcoma rhabdomyosarcoma), inflammatory lesions and infectious processes. The SELSTOC (Self Limiting Sternal Tumours of Childhood) are entities of non-specific origin, they are self-limiting and characterised by a rapidly growing tumour that disappears spontaneously with no history of trauma or active infection. Read More
World Neurosurg 2018 Sep 29;122:1-7. Epub 2018 Sep 29.
Division of Neurosurgery, Hamilton General Hospital, McMaster University, Hamilton, Ontario, Canada.
Intracranial chondromas are rare, benign neoplasms representing only 0.2%-0.3% of neoplastic intracranial lesions. Read More
J Surg Case Rep 2018 Sep 21;2018(9):rjy247. Epub 2018 Sep 21.
Department of Hematology and Oncology, Lifespan Cancer Institute Providence, Rhode Island 02903, USA.
Background: Osteochondromas are the most common tumors of the long bones in children. Osteochondromas can rarely be seen in the chest wall and they are usually diagnosed at a young age. They can be sporadic or part of the hereditary multiple exostoses. Read More
Oncol Lett 2018 Oct 1;16(4):5167-5171. Epub 2018 Aug 1.
Department of Orthopedics, The Tongde Hospital of Zhejiang, Hangzhou, Zhejiang 310012, P.R. China.
Multiple osteochondromas (MO) is an autosomal inherited disease that is characterized by benign bone tumors. However, the underlying mechanism of MO at a molecular level requires further investigation. The majority of mutations associated with MO occur in the exostosin glycosyltransferase genes ( or . Read More
Clin Neuropathol 2018 Sep 20. Epub 2018 Sep 20.
Cancer Biomark 2018 Aug 28. Epub 2018 Aug 28.
Department of Orthopaedic Surgery, Shengjing Hospital of China Medical University, Shenyang 110000, Liaoning, China.
We analyzed the expression of miR-503 in osteosarcoma tissues (OS) and discussed the clinical significance of our findings. To provide a theoretical basis for clinical applications, prognosis prediction and treatment of osteosarcoma, we studied the biological function of miR-503 and its mechanism in MG63 osteosarcoma cells. Real-time polymerase chain reaction (PCR) was used to detect the expression of miR-503 in 45 OS tissues and 20 osteochondroma tumors, analyzing the relationship between clinical pathology and follow-up data. Read More
Ann Vasc Surg 2018 Sep 12. Epub 2018 Sep 12.
Department of Vascular Surgery, "Democritus" University of Thrace, Medical School, University General Hospital of Alexandroupolis, Alexandroupolis, Greece. Electronic address:
Background: Osteochondromas or exostoses are the most common benign tumors of the bones, which appear during the growth period. The involvement of lower extremities is common, particularly in metaphyseal structures of the femur and humerus and around the knee joint. However, the incidence of the development of the tumor at the proximal fibula is rare. Read More
J Spinal Cord Med 2018 Sep 12:1-6. Epub 2018 Sep 12.
a Department of Orthopedics, Tongji Hospital, Tongji Medical College , Huazhong University of Science and Technology , Wuhan , Hubei , People's Republic of China.
Context: Osteochondroma is the most common benign tumor of the bone, but spinal osteochondroma is rare. We report a case of cervical osteochondroma in multiple exostoses arising from the lamina of the C2 vertebra, presenting with features of compressive myelopathy in a 22-year-old male. Total resection of the tumor and atlantoaxial fixation and fusion after reconstruction of the C1 posterior arch were performed. Read More
J Oral Biol Craniofac Res 2018 Sep-Dec;8(3):203-205. Epub 2017 Jul 1.
Department of Oral Pathology, Government Dental College and Hospital, St. George Hospital Campus, Near Chhatrapati Shivaji Terminus Area, Fort, Mumbai, Maharashtra 400001, India.
Radiolucent lesions of Temporomandibular Joint (TMJ) represent a diagnostic challenge and a treatment conundrum. Biopsy of the lesions is technically difficult owing to their complex anatomy. The Differential Diagnosis (DD) includes a wide array of lesions including Simple Bone Cyst, Ameloblastoma, Central Giant Cell Granuloma, Hemangioma, Osteoblastoma, Osteochondroma, Chondroblastoma, Chondrosarcoma, Neurofibroma and metastatic malignant lesions though none has a specific predilection for TMJ. Read More
J Orthop Surg (Hong Kong) 2018 May-Aug;26(3):2309499018798180
1 Department of Orthopaedics and Traumatology, Baltalimani Bone and Joint Diseases Training and Research Hospital, Istanbul, Turkey.
Purpose: Primary bone tumors of the fibula are rare. There are only a few studies reporting the incidence, histologic, and anatomic distribution of primary fibula tumors. This study aimed to comprehensively report the incidence, presenting symptoms, and histologic tumor types with the anatomic and histologic distribution of primary bone tumors of the fibula. Read More
J Coll Physicians Surg Pak 2018 Sep;28(9):S190-S191
Department of Orthopaedics, Pt. B. D. Sharma PGIMS, Rohtak, Haryana, India.
Osteochondroma is the most common benign tumour of bone seen in 3% of the general population. Complications such as neurological compromise, skeletal defects, vascular lesions, and compartment syndrome occur in about 4% of osteochondromas. We bring forth the case of a 16-year male who presented with the complaints of swelling in calf region associated with symptoms of claudication and paraesthesias in leg after exertion and absence of any such complaints at rest. Read More
Medicine (Baltimore) 2018 Aug;97(35):e11894
Department of Respiratory Diseases, University Hospital, Reims, France.
Rationale: Hereditary multiple exostoses (HME) is a genetic musculoskeletal condition causing multiple exostoses. Rib location of exostosis can be complicated by thoracic injuries.
Patient Concerns And Diagnoses: We report a case of pneumothorax in a 32-year-old man with a partial left-sided pneumothorax caused by an exostosis of the fourth and fifth ribs. Read More
AJR Am J Roentgenol 2018 Oct 30;211(4):910-919. Epub 2018 Aug 30.
1 Department of Radiology, The Children's Hospital of Philadelphia, 3NW39, 3401 Civic Center Blvd, Philadelphia, PA 19104.
Objective: The purpose of this article is to discuss approaches to imaging dysplasia epiphysealis hemimelica in the context of recent advances in the understanding of the underlying pathophysiologic profile of this entity, which may result in pain, growth disturbance, and early development of osteoarthritis.
Conclusion: Dysplasia epiphysealis hemimelica was first characterized as a skeletal disorder with osteochondromas characteristically involving epiphyses on one side of the same lower extremity. Upper extremity involvement was subsequently recognized. Read More
Case Rep Orthop 2018 12;2018:8280415. Epub 2018 Jul 12.
Department of Pathology & Laboratory Medicine, King Faisal Hospital, OSHEN, Kigali, Rwanda.
Introduction: Multiple hereditary exostoses (MHE) is a rare autosomal dominant disorder characterized by the presence of multiple skeletal deformities. They are painless slow-growing lesions. Malignant transformation tends to occur later in adulthood and has only been seen in 1-5% of patients. Read More
Cancer Cell Int 2018 13;18:115. Epub 2018 Aug 13.
2Department of Orthopedic Research Center, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei People's Republic of China.
Background: Increasing data has indicated an association between increased soluble B7-H3 (sB7-H3) levels and unfavorable prognosis in patients with malignancies. However, the level of sB7-H3 and its clinical significance in osteosarcoma (OS) are not well known. In this present study, we investigated whether sB7-H3 levels in serum could be as a tool for differential diagnosis of OS patients. Read More
J Pediatr Genet 2018 Sep 7;7(3):122-124. Epub 2018 Mar 7.
Department of Pediatrics, Hospital de San José, Bogotá D.C., Colombia.
Multiple hereditary exostoses (MHE) is a rare disease with autosomal dominant inheritance, caused by heterozygous germline mutations in the or genes. This disorder is characterized by the growth of prominences surrounded by cartilage in the growth plates and the long bones. Here, we report a family affected by MHE. Read More
Isr Med Assoc J 2018 Aug;20(8):527
Department of Orthopedic Surgery, Sheba Medical Center, Tel-Hashomer, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Israel.
Pan Afr Med J 2018 2;29:193. Epub 2018 Apr 2.
Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria.
Introduction: Bone tumours are relatively rare in comparison with neoplasms in other parts of the body. Previous studies have noted higher frequencies of these tumours in young adults with potentially devastating consequences.
Methods: This study aimed to demonstrate the histopathological pattern of primary bone tumours and tumour-like lesions in Ile-Ife, Nigeria with emphasis on relative frequencies and distribution according to age, sex and anatomical location. Read More
J Clin Med 2018 Jul 30;7(8). Epub 2018 Jul 30.
Department of Orthopaedic Surgery, Kanazawa Medical University, Daigaku 1-1, Uchinada, Kahoku-gun, Ishikawa 920-0293, Japan.
Synovial osteochondromatosis (SO) is a rare disease in which chondrometaplasia develops in the synovium of joints, bursa, and tendon sheaths. SO is found most frequently in the knee joint, while cases of SO developing in the shoulder joint are rare, accounting for only 1.9⁻5. Read More
BMC Cancer 2018 Jul 13;18(1):735. Epub 2018 Jul 13.
Klinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar der Technischen, Universität München, Ismaningerstr.22, 81675, München, Germany.
Background: Bone and soft tissue masses of the foot and ankle are not particularly rare but true neoplasia has to be strictly differentiated from pseudotumorous lesions. Diagnosis is often delayed as diagnostic errors are more common than in other regions. Awareness for this localization of musculoskeletal tumors is not very high and neoplasia is often not considered. Read More
Anat Cell Biol 2018 Jun 27;51(2):136-138. Epub 2018 Jun 27.
Department of Anatomy, Melaka Manipal Medical College (Manipal Campus), Manipal Academy of Higher Education, Manipal, India.
Osteochondromas develop as cartilaginous nodules in the periosteum of bones. They are the commonest benign tumors of the skeleton, generally observed in the long bones. Rarely, they are also found in the axial skeleton, flat bones of skull and facial bones. Read More
Global Spine J 2018 Jun 1;8(4):323-339. Epub 2017 Jun 1.
University of Louisville, Louisville, KY, USA.
Study Design: Case series and literature review.
Objective: There is a growing body of literature supporting that osteochondroma of the spine may not be as rare as previously documented. The purpose of this study was to perform an updated review and present our experience with 4 cases of solitary osteochondroma of the spine, including surgical treatment and subsequent outcomes. Read More
J Cancer Res Ther 2018 ;14(4):892-895
Department of Oncology, Lishui Central Hospital, Zhejiang Lishui, PR China.
Objective: The objective of this study is to evaluate the association between expression of CD133 protein and the clinicopathological features of patients with osteosarcoma.
Methods: This study retrospectively analyzed 28 cases of osteosarcoma in our hospital from 2007 to 2016, as well as 21 cases of osteochondroma in the same period as control group. The expression of CD133 protein in paraffin specimens of two groups of patients was detected with immunohistochemistry SP assay. Read More
BMJ Case Rep 2018 Jun 27;2018. Epub 2018 Jun 27.
Pediatric Orthopaedic Associates, East Brunswick, New Jersey, USA.
Pseudoaneurysms adjacent to exostoses have been commonly reported in the femoral and popliteal arteries and only rarely in the upper extremity. We describe a case of an 18-year-old man with multiple hereditary exostoses who developed a brachial artery pseudoaneurysm after minor trauma to his right upper arm, adjacent to a known lesion. He was referred to a vascular surgeon who removed the pseudoaneurysm and repaired the artery with a saphenous vein graft. Read More
J Clin Orthop Trauma 2018 Jun 29;9(Suppl 2):S5-S7. Epub 2017 Dec 29.
Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.
Am J Phys Med Rehabil 2018 Jun 13. Epub 2018 Jun 13.
Department of Radiology, Medical Faculty, Ataturk University, Erzurum, Turkey.
Osteochondroma is the most common benign bone tumor but it rarely arises from the scapula. Scapulothoracic bursitis is quite rare and osteochondroma is one of the unusual causes of this condition. Synovial chondromatosis may occur extremely uncommonly in this bursa. Read More
Br J Oral Maxillofac Surg 2018 Jul 9;56(6):505-509. Epub 2018 Jun 9.
IPS Center, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Japan. Electronic address:
We have introduced an effective treatment for mandibular condylar osteochondroma with a digital cutting guide and endoscopically-assisted vertical ramus osteotomy (VRO). Eleven patients with unilateral condylar osteochondroma, who did not require orthognathic surgery or had less than 3mm deviation of the chin and a stable occlusion, were treated during the period April 2013-January 2017 with a digital cutting guide and endoscopically-assisted VRO. Clinical data collected included the occlusion, facial contour, and maximum mouth opening (MMO). Read More
J Orthop 2018 Jun 17;15(2):384-387. Epub 2018 Mar 17.
Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Shogoin, Kawahara-cho 54, Sakyo-ku, Kyoto 606-8507, Japan.
Osteochondromas are benign bone tumors that protrude from underlying bone. A fracture of an osteochondroma is rare, and no insufficiency fractures of an osteochondroma have been reported. A 57-year-old female complained of pain in her proximal leg that increased during walking. Read More
Ann Vasc Surg 2018 Oct 19;52:313.e1-313.e3. Epub 2018 May 19.
Service de chirurgie vasculaire périphérique, CHU Ibn Sina, Rabat, Morocco.
Exostoses or osteochondromas are benign osseous tumors that develop on the bone surface and can be sporadic or hereditary. Their evolution is generally benign, but they may be complicated in some patients by conflicts with the surrounding nervous or vascular structures, in particular arteries. We report a case of false aneurysm of the popliteal artery secondary to an isolated exostosis of the left femur in a 20-year-old woman. Read More
Case Rep Orthop 2018 31;2018:7018109. Epub 2018 Jan 31.
Centre de recherche FRQS du CHU de Québec, Hôpital Enfant-Jésus, 1401 18ème Rue, Ville de Québec, QC, Canada G1J 1Z4.
Osteochondroma is the most common benign bone tumor and is characterized as a cartilage-capped bony stalk. This lesion usually develops from the growth plate of long bones. Most osteochondromas are asymptomatic. Read More
World Neurosurg 2018 Aug 18;116:247-248. Epub 2018 May 18.
Avicenne Military Hospital, Marrakech, and Department of Neurosurgery, Mohammed V University, Rabat, Morocco.
This is a case report of a 34-year-old man with hereditary multiple exostoses who presented with gradual tetraparesis. Neuroimaging evaluation revealed an important posterior spinal cord compression by a C3 bony formation. Following posterior microsurgical decompression, the patient recovered nearly completely. Read More
Case Rep Orthop 2018 12;2018:9347145. Epub 2018 Mar 12.
Department of Orthopaedic Surgery, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8606, Japan.
Thoracic outlet syndrome (TOS) is caused by heterogeneous factors that compress the brachial plexus and subclavian artery; tumor is rarely a cause of TOS. Here, we present the case of a 26-year-old man with secondary chondrosarcoma arising from osteochondroma of the left clavicle causing TOS, with a direct compression of the brachial plexus and subclavian artery. Immediately after surgery, the symptoms of TOS reduced. Read More
Int J Dermatol 2018 Jul 27;57(7):872-881. Epub 2018 Apr 27.
Department of Radiology, University of Health Sciences, Haydarpaşa Numune Training and Research Hospital, İstanbul, Turkey.
Background: Subungual exostosis (SE) and subungual osteochondroma (SO) are an uncommon, benign tumor of the distal phalanx. The purpose of this retrospective study was to evaluate clinical, demographical, and radiological features; treatment modalities; and follow-up results in SE and SO cases.
Methods: Twenty-five cases were confirmed histopathologically as SE or SO. Read More
Medicine (Baltimore) 2018 Apr;97(17):e0512
Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University.
Rationale: Metachondromatosis (MC) is a very rare genetic disease, which is infrequently reported worldwide, which leads to osteochondroma and enchondromatosis. The disease has been shown to be associated with loss of function of the tumor suppressor gene "protein tyrosine phosphatase, non-receptor type 11" (PTPN11).
Patient Concerns: A 12-year-old female was admitted to the hospital with pain due to an enlarged mass in her left fifth finger. Read More
Medicine (Baltimore) 2018 Apr;97(17):e0510
Department of Orthopaedic Surgery, Soonchunhyang University Hospital Seoul, Daesagwan-ro, Yongsan-gu, Seoul, Korea.
Rationale: The scapula is relatively rare site for osteochondroma. Scapula osteochondroma is usually asymptomatic, however it may present with features such as pseudowinging, snapping scapula, bursa formation, chronic pain, and cosmetic deformities. To our best knowledge, this is the first report in the English literature about osteochondroma of ventral scapula associated with chest pain due to rib cage compression. Read More
J Coll Physicians Surg Pak 2018 May;28(5):415
Department of Dentistry, Sarder Patel (SP) Medical College, Bikaner, Rajasthan, India.
J Stomatol Oral Maxillofac Surg 2018 Sep 21;119(4):348-353. Epub 2018 Apr 21.
Selcuk University, Faculty of Medicine, Department of Pathology, Konya, Turkey.
Objective: The aim of this case report is to evaluate the clinical outcomes that including minor postoperative complications of the transport distraction osteogenesis (TDO) for reconstruction of the ramus-condyle unit.
Study Design: We present 3 cases of the ramus-condyle unit reconstruction after the resection of bone tumors. All three bone tumors were excised intraoperatively and the histologic assessment confirmed the clinical diagnosis of osteochondroma, condylar hyperplasia, and osteoma. Read More
J Oral Maxillofac Surg 2018 Sep 31;76(9):1912-1916. Epub 2018 Mar 31.
Department of Oral and Maxillofacial Surgery, MedStar Washington Hospital Center, Washington, DC.
An osteochondroma, when reported in the maxillofacial region, is a benign neoplasm that involves the skull base, maxillary sinus, zygomatic arch, or mandible. Most commonly, the osteochondroma occurs in the coronoid process and the condyle. One rare subtype of osteochondroma reported in the literature, termed Jacob disease, arises from the coronoid process and interferes with the zygomatic arch. Read More
Case Rep Orthop 2018 5;2018:5145642. Epub 2018 Feb 5.
Department of Orthopedic Surgery, Eiju General Hospital, 2-3-23 Higashiueno, Taito-ku, Tokyo 110-8645, Japan.
Osteochondroma (OC) is the most common benign bone tumor and may occur on any bone in which endochondral ossification develops. Although scapular OC accounts for less than 5% of the cases of solitary OC, OC is the most common lesion among the tumors and tumor-like lesions of the scapula. OC that develops near the medial scapular border easily causes friction with the ribcage; hence, almost half the number of cases of OC associated with marked bursa formation develops in the ventral scapula. Read More