3,220 results match your criteria Osgood-Schlatter Disease


Is Sclerostin Glycoprotein a Suitable Biomarker for Equine Osteochondrosis?

J Equine Vet Sci 2018 May 13;64:27-33. Epub 2017 Nov 13.

Anesthésiologie générale et pathologie chirurgicale des grands animaux. University of Liège, Liège, Belgium; Equine Research and Development Center, Mont-le-Soie, Belgium.

Osteochondrosis (OC) disease appears to be multifactorial in origin, including skeletal growth rates, nutrition, endocrinological factors, exercise, biomechanics, and other environmental factors. Endocrinological and metabolic factors seem to have an important role in the pathogeny of OC like the Wnt signaling pathway. One of the regulators in the Wnt signaling pathway is the sclerostin glycoprotein. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07370806173041
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http://dx.doi.org/10.1016/j.jevs.2017.11.003DOI Listing
May 2018
5 Reads

Familial, long-term pollakisuria as initial manifestation of HSP4 due to the SPAST variant c.683-2A>C.

J Clin Neurosci 2019 Apr 5. Epub 2019 Apr 5.

Institute of Medical Genetics, Head of the Section "Clinical Genetics", Medical School of Vienna, Vienna, Austria. Electronic address:

Objective: Hereditary spastic paraplegia type-IV (HSP4) is the most common of the autosomal-dominant HSPs. Though urinary dysfunction is a frequent phenotypic feature, long-term pollakisuria as the initial manifestation of HSP4 has not been reported.

Case Report: The patient is a 56yo female with an uneventful history until age 46y, when she developed pollakisuria. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868193038
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http://dx.doi.org/10.1016/j.jocn.2019.03.067DOI Listing
April 2019
2 Reads

Osteochondrosis of the tarsal navicular and medial cuneiform in a child.

Proc (Bayl Univ Med Cent) 2018 Oct 17;31(4):539-540. Epub 2018 Sep 17.

Department of Radiology, Baylor University Medical CenterDallasTexas.

A 6-year-old boy presented to his primary care physician with complaints of left foot pain after minor recent trauma. Left foot radiographs demonstrated osteochondrosis of the tarsal navicular (also known as Kohler's disease) and medial cuneiform-benign self-limiting processes, though likely the source of the patient's pain. Read More

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http://dx.doi.org/10.1080/08998280.2018.1494465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413999PMC
October 2018
2 Reads

[Knee pain in children and adolescents].

Ugeskr Laeger 2019 Mar;181(13)

Knee pain is common among children and adolescents, and the most usual knee conditions are patellofemoral pain and Osgood-Schlatter disease. Long-standing knee pain often leads to reduced physical activity levels, and one in two continue to experience knee pain for years. Education of the patients and strategies to improve the ability of them to manage knee pain should be the mainstay of treatment for these types of knee pain. Read More

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March 2019
1 Read

Not just for boys: a rare case of symptomatic Osgood-Schlatter disease in a skeletally mature woman.

BMJ Case Rep 2019 Mar 26;12(3). Epub 2019 Mar 26.

Department of Medicine, Tripler Army Medical Center, Tripler, Hawaii, USA.

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http://dx.doi.org/10.1136/bcr-2018-228963DOI Listing
March 2019
1 Read

Persisting Isolated Metacarpal Swelling and Pain in Adolescence: Consider Osteochondrosis.

J Pediatr 2019 Mar 7. Epub 2019 Mar 7.

University of Trieste, Trieste, Italy; Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.

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http://dx.doi.org/10.1016/j.jpeds.2019.01.033DOI Listing
March 2019
2 Reads

Osteochondritis dissecans (OCD) in Horses - Molecular Background of its Pathogenesis and Perspectives for Progenitor Stem Cell Therapy.

Stem Cell Rev 2019 Feb 23. Epub 2019 Feb 23.

Department of Experimental Biology, Faculty of Biology and Animal Science, Wrocław University of Environmental and Life Sciences, Norwida 27B, 50-375, Wrocław, Poland.

Osteochondrosis (osteochondrosis dissecans; OCD) is a disease syndrome of growing cartilage related to different clinical entities such as epiphysitis, subchondral cysts and angular carpal deformities, which occurs in growing animals of all species, including horses. Nowadays, these disorders are affecting increasing numbers of young horses worldwide. As a complex multifactorial disease, OCD is initiated when failure in cartilage canals because of existing ischemia, chondrocyte biogenesis impairment as well as biochemical and genetic disruptions occur. Read More

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http://dx.doi.org/10.1007/s12015-019-09875-6DOI Listing
February 2019
1 Read

Fragmentation of the dorsal distal aspect of the talus on weanling survey and pre-sale radiographs of juvenile Thoroughbreds: prevalence and 2- and 3-year-olds racing performance.

Aust Vet J 2019 Mar 17;97(3):68-74. Epub 2019 Feb 17.

Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, 250 Princes Hwy, Werribee, Victoria 3030, Australia.

Background: Fragmentation of the dorsal aspect of the distal talus (FDDT), at the dorsolateral articular margin of the proximal intertarsal joint (PITJ) on pre-sale radiographs of yearling Thoroughbreds has not been previously described and data to support decisions made by veterinarians to predict future racing potential of horses with these lesions are lacking.

Methods: In this retrospective case-control study we aimed to determine the prevalence of FDDT in juvenile Thoroughbreds and to report their race records. From a database of survey and repository radiographic examinations of 5709 horses, 36 with FDDT were identified. Read More

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http://dx.doi.org/10.1111/avj.12787DOI Listing

Efficacy, chondrotoxicity and plasma concentrations of tramadol following intra-articular administration in horses undergoing arthroscopy: preliminary findings.

Vet Q 2018 Dec;38(1):129-137

a Department of Veterinary Medicine , University of Perugia , Perugia , Italy.

Intra-articular administration of analgesics is performed to ensure good perioperative pain management avoiding undesirable systemic effects. To evaluate the effect of intra-articular injection of tramadol on postoperative pain after arthroscopy in horses and to determine whether tramadol had a local effect. Before the in vivo study, an in vitro test was performed aiming to evaluate the viability of equine chondrocytes after exposure to various concentrations of tramadol. Read More

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http://dx.doi.org/10.1080/01652176.2018.1546963DOI Listing
December 2018
1 Read

Köhler Disease: Avascular Necrosis in the Child.

Foot Ankle Clin 2019 Mar 10;24(1):83-88. Epub 2018 Dec 10.

Department of Orthopaedics, Stanford University, 300 Pasteur Drive, Edwards Building, R 105, Stanford, CA 94305-5341, USA. Electronic address:

Köhler disease is a childhood condition of pain and swelling of the medial midfoot with associated osteochondrosis or avascular necrosis of the tarsal navicular. The age at presentation is between 2 and 10 years, with boys more likely to be affected than girls. Radiographs show increased sclerosis and sometimes flattening and fragmentation of the navicular. Read More

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http://dx.doi.org/10.1016/j.fcl.2018.09.005DOI Listing
March 2019
3 Reads

Freiberg Disease and Avascular Necrosis of the Metatarsal Heads.

Foot Ankle Clin 2019 Mar;24(1):69-82

Department of Orthopedic Surgery, University of Colorado School of Medicine, 12631 E. 17th Avenue, Aurora, CO 80045, USA. Electronic address:

Freiberg disease is characterized as osteochondrosis of the second metatarsal head. It is the fourth most common form of primary osteochondrosis with a significant predilection to the adolescent athletic female population, although it has been seen over a wide age range. If treated early, osteochondroses such as Freiberg disease are essentially self-limiting, often resolving with nonoperative management. Read More

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http://dx.doi.org/10.1016/j.fcl.2018.11.003DOI Listing
March 2019
5 Reads

Trends in Treatment of Scheuermann Kyphosis: A Study of 1,070 Cases From 2003 to 2012.

Spine Deform 2019 01;7(1):100-106

Department of Orthopaedics, NYU Langone Orthopedic Hospital, 301 East 17th St, New York, NY 10003, USA. Electronic address:

Study Design: Retrospective review of KID Inpatient Database (KID) from 2003, 2006, 2009, and 2012.

Objectives: The aim of this study was to evaluate the impact of advances in spinal surgery on patient outcomes in the treatment of Scheuermann kyphosis (SK).

Summary Of Background Data: SK is one of the most common causes of back pain in adolescents. Read More

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http://dx.doi.org/10.1016/j.jspd.2018.06.004DOI Listing
January 2019
4 Reads

[Problems of the diagnosis and treatment of compression neuropathy of the median nerve: an analysis of typical medical practice].

Zh Nevrol Psikhiatr Im S S Korsakova 2018;118(11):30-34

Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow StateMedical University of the Ministry of Health of the Russian Federation, Moscow, Russia.

Aim: An analysis of typical medical errors in the diagnosis and treatment of compression neuropathy of the median nerve at the level of the wrist (carpal tunnel syndrome - CTS).

Material And Methods: Previous diagnoses and treatment of 85 patients with CTS (14 men and 71 women), aged from 36 to 84 years (middle age 62±10.6 years), who underwent surgery in our clinics were evaluated. Read More

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http://dx.doi.org/10.17116/jnevro201811811130DOI Listing
January 2018
2 Reads

Is There a Relationship between Patellofemoral Alignment and Osgood-Schlatter Disease? A Case-Control Study.

J Knee Surg 2018 Dec 21. Epub 2018 Dec 21.

Department of Orthopaedics, Adana City Research and Education Hospital, Adana, Turkey.

This study was aimed to investigate the role of anatomic variations in patellofemoral alignment in patients with or without Osgood-Schlatter disease (OSD) and to determine the potential anatomic risk factors that may play role in the etiology. This prospective observational case-control study was conducted on two groups of adolescent patients. Group 1 comprised patients who were diagnosed as having OSD and group 2 consisted of an equal number of age-matched patients who presented to the outpatient clinic with traumatic knee injury and underwent knee radiographic examination but without a diagnosis of OSD. Read More

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http://dx.doi.org/10.1055/s-0038-1676523DOI Listing
December 2018
3 Reads

Identification of Areas of Epiphyseal Cartilage Necrosis at Predilection Sites of Juvenile Osteochondritis Dissecans in Pediatric Cadavers.

J Bone Joint Surg Am 2018 Dec;100(24):2132-2139

Department of Veterinary Clinical Sciences, University of Minnesota, St. Paul, Minnesota.

Background: The pathogenesis of human juvenile osteochondritis dissecans (JOCD) remains poorly understood, with multiple factors implicated, including ischemia, repetitive trauma, and genetic predisposition. Similarities in the predilection site and the diagnostic and clinical features of JOCD to the well-characterized veterinary counterpart, osteochondrosis dissecans, suggest that, similar to the animal disease, the pathogenesis JOCD may also be initiated in the first few years of life, when disruption of blood supply to the epiphyseal growth cartilage leads to failure of endochondral ossification. To gather data in support of the hypothesis that JOCD and osteochondrosis dissecans have a shared pathogenesis, biopsy specimens obtained from predilection sites of JOCD in juvenile human cadavers were histologically examined to determine whether they contained lesions similar to those found in animals diagnosed with subclinical osteochondrosis dissecans. Read More

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http://dx.doi.org/10.2106/JBJS.18.00464DOI Listing
December 2018
3 Reads

Osgood-Schlatter Disease Unveiled Under High-frequency Ultrasonogram.

Authors:
Md Abu B Siddiq

Cureus 2018 Oct 4;10(10):e3411. Epub 2018 Oct 4.

Physical Medicine and Rheumatology, Brahmanbaria Medical College, Brahmanbaria, BGD.

Osgood-Schlatter disease is a painful condition, affecting the tibial tuberosity of physically active children with a painful bump that aggravates with repetitive impacts over the affected area during exercise, sports, or even usual daily activities. The condition is usually unilateral; however, bilateral presentation is not unlikely. In addition to clinical features, a unique radiological finding appears worthy in terms of accurate diagnosis. Read More

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http://dx.doi.org/10.7759/cureus.3411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281446PMC
October 2018

Prevalence of osteochondral lesions in the fetlock and hock joints of Standardbred horses that survived bacterial infection before 6 months of age.

BMC Vet Res 2018 Dec 10;14(1):390. Epub 2018 Dec 10.

Equine Section, Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ullevålsveien 72, 0454, Oslo, Norway.

Background: Young Standardbred horses frequently develop fragments in joints. Some fragments represent osteochondrosis; others are considered developmental, but it is uncertain whether they result from preceding osteochondrosis. Osteochondrosis occurs as a consequence of failure of the cartilage canal blood supply and ischaemic chondronecrosis. Read More

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http://dx.doi.org/10.1186/s12917-018-1726-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288956PMC
December 2018
1 Read

[SUBSTANTIATION OF INDICATIONS FOR BIOFEEDBACK THERAPY AND CYTOFLAVIN APPLICATION IN TREATMENT OF OSTEOCHONDROSIS NEUROLOGICAL COMPLICATIONS IN ELDERLY PATIENTS].

Georgian Med News 2018 Oct(283):89-96

GBUZ "City Polyclinic №91", St. Petersburg; North-West Institute of Management of RANEPA, St. Petersburg; Institute of Toxicology, Federal Biomedical Agency, St. Petersburg.

The aim of the study was to assess the impact of cytoflavin and bioflavin therapy on the dynamics of clinical and psychophysiological status of patients with Osteochondrosis. 150 patients with osteochondrosis of a backbone were investigated. The patients were divided into two groups using method of randomization: the main group - 75 patients - and control group -75 patients. Read More

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October 2018
2 Reads

Panner's Disease: The Vacuum Phenomenon Revisited.

J Belg Soc Radiol 2018 Oct 12;102(1):67. Epub 2018 Oct 12.

AZ Sint-Maarten and University (Hospital) Antwerp/Ghent, BE.

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http://dx.doi.org/10.5334/jbsr.1647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196578PMC
October 2018
3 Reads

Use of a locking compression plate for equine proximal interphalangeal joint arthrodesis: 29 cases (2008-2014).

J Am Vet Med Assoc 2018 Dec;253(11):1460-1466

OBJECTIVE To describe clinical use of a locking compression plate (LCP) for proximal interphalangeal joint (PIPJ) arthrodesis in horses and compare outcomes for horses that underwent the procedure as treatment for fracture of the middle phalanx (P2) versus other causes. DESIGN Retrospective case series. ANIMALS 29 client-owned horses. Read More

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https://avmajournals.avma.org/doi/10.2460/javma.253.11.1460
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http://dx.doi.org/10.2460/javma.253.11.1460DOI Listing
December 2018
11 Reads

Increased Patellar Volume/Width and Decreased Femoral Trochlear Width Are Associated With Adolescent Patellofemoral Pain.

Clin Orthop Relat Res 2018 Dec;476(12):2334-2343

R. M. Smith. F. T. Sheehan, Functional and Applied Biomechanics, Department of Rehabilitation Medicine, National Institutes of Health, Bethesda, MD, USA B. P. Boden MD, The Orthopaedic Center, Rockville, MD, USA.

Background: Patellofemoral pain is one of the most common forms of knee arthralgia in adolescent females. Unlike in adults, in whom the etiology of patellofemoral pain is considered to be multifactorial (eg, altered bone shape and musculoskeletal dynamics), the etiology of adolescent patellofemoral pain has been historically attributed to overuse. Although it is highly plausible that adolescent patellofemoral pain results from excessive maltracking, as suggested by recent research, an increase in patellar, relative to femoral, size could also contribute to patellofemoral pain through altered cartilage stresses/strains, resulting in overloading of the subchondral bone. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259899PMC
December 2018
12 Reads

Pediatric musculoskeletal ultrasound: a pictorial essay.

J Ultrasound 2018 Nov 9. Epub 2018 Nov 9.

Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.

Ultrasound (US) is the main imaging modality for the evaluation of pediatric patients with musculoskeletal diseases; particularly, it is an appropriate and reliable tool for diagnosis, follow-up and treatment of several musculoskeletal pathologies affecting the pediatric age. High-frequency (10-15 MHz) and high-resolution probes provide very lofty quality images, allowing a detailed study of the pediatric musculoskeletal system. Among the well-known advantages of this technique-such as the absence of ionizing radiations, its low cost and wide availability-US can as well rely on some intrinsic characteristics of the pediatric musculoskeletal system that can improve its diagnostic capability. Read More

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http://link.springer.com/10.1007/s40477-018-0337-y
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http://dx.doi.org/10.1007/s40477-018-0337-yDOI Listing
November 2018
24 Reads

The Young Injured Gymnast: A Literature Review and Discussion.

Curr Sports Med Rep 2018 Nov;17(11):366-375

Division of Sports Medicine, Department of Orthopaedics, Boston Children's Hospital; Harvard Medical School, Boston, MA; The Micheli Center for Sports Injury Prevention, Waltham, MA.

Gymnastics is a sport requiring grace, strength, and flexibility, resulting in a wide variety of injuries. This article is an overview of the sport of gymnastics and associated injury trends in the artistic gymnastics population. Injury rates in gymnastics range from 1. Read More

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http://dx.doi.org/10.1249/JSR.0000000000000536DOI Listing
November 2018
3 Reads

Effectiveness of interventions for treating apophysitis in children and adolescents: protocol for a systematic review and network meta-analysis.

Chiropr Man Therap 2018 23;26:41. Epub 2018 Oct 23.

5Centre for Clinical Epidemiology, Jewish General Hospital, McGill University, Ottawa, Canada.

Background: Overuse injuries are reported to be more common than acute trauma in children and adolescents, causing pain and reduced function. The most common is apophysitis - a traction injury to the apophysis in growing individuals. The duration of symptoms reported in the literature is between 6 weeks to 6 months or more. Read More

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http://dx.doi.org/10.1186/s12998-018-0209-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198434PMC
October 2018
3 Reads

SNP-based heritability and genetic architecture of tarsal osteochondrosis in North American Standardbred horses.

Anim Genet 2019 Feb 24;50(1):78-81. Epub 2018 Oct 24.

Veterinary Population Medicine Department, University of Minnesota, 225 Veterinary Medical Center, 1365 Gortner Avenue, St. Paul, MN, 55108, USA.

Osteochondrosis is a common developmental orthopedic disease characterized by a failure of endochondral ossification. Standardbred horses are recognized as being predisposed to tarsal osteochondrosis. Prior heritability estimates for tarsal osteochondrosis in European Standardbreds and related trotting breeds have been based on pedigree data and range from 17-29%. Read More

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http://doi.wiley.com/10.1111/age.12738
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http://dx.doi.org/10.1111/age.12738DOI Listing
February 2019
13 Reads

Quality of Life Improvement Following Surgery in Adolescent Spinal Deformity Patients: A Comparison Between Scheuermann Kyphosis and Adolescent Idiopathic Scoliosis.

Spine Deform 2018 Nov - Dec;6(6):676-683

Department of Orthopaedic Surgery, Rady Children's Hospital San Diego, 3020 Children's Way, MC 5069, San Diego, CA 92123-4282, USA.

Study Design: Preoperative and two-year follow-up health-related quality of life (HRQOL) data were prospectively collected in 82 Scheuermann kyphosis (SK) and 995 adolescent idiopathic scoliosis (AIS) patients using the Scoliosis Research Society-22 patient questionnaire (SRS-22) outcomes instrument in a multicenter study. Visual analog scale (VAS) scores were also collected for the SK population.

Objectives: This study assessed changes in HRQOL prospectively and compared them to those occurring in AIS. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S2212134X183007
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http://dx.doi.org/10.1016/j.jspd.2018.04.009DOI Listing
February 2019
24 Reads

[The association of gamma-synuclein autoantibodies with the polymorphism in exon 4 of the coding gene].

Zh Nevrol Psikhiatr Im S S Korsakova 2018;118(9):68-70

Institute of Physiologically Active Compounds RAS, Chernogolovka, Russia.

Aim: To analyze the polymorphism in exon 4 of the gamma-synuclein gene (SNCG) in patients with autoantibodies against the gamma-synuclein protein.

Material And Methods: To identify autoantibodies against gamma-synuclein, the serum from patients with chronic cerebral ischemia and cervical osteochondrosis was used. All patients were women of the Slavic ethnic group, mean age 61±5 years. Read More

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http://dx.doi.org/10.17116/jnevro201811809168DOI Listing
March 2019
8 Reads

Blount's disease successfully treated with intraepiphyseal osteotomy with elevation of the medial plateau of the tibia-a case report with 65 years' follow-up.

Acta Orthop 2018 Dec 17;89(6):699-701. Epub 2018 Oct 17.

b Department of Paediatric Orthopaedics , Zagreb Children's Hospital , Zagreb , Croatia.

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http://dx.doi.org/10.1080/17453674.2018.1516179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300735PMC
December 2018
2 Reads

Joint debridement and microfracture for treatment late-stage Freiberg-Kohler's disease: Long-term follow-up study.

Foot Ankle Surg 2018 Feb 27. Epub 2018 Feb 27.

Operative Unit of Orthopaedics and Traumatology, Israelite Hospital, Rome, Italy. Electronic address:

Background: Freiberg-Kohler's disease is not a common disease and although various reports have been described since 1914, treatment methods are not completely established. The purpose of the present retrospective study was to evaluate the long-term outcomes following joint debridement and microfracture procedures for the treatment of Freiberg-Kohler's disease.

Methods: Fifteen consecutive patients (16 feet) with Freiberg-Kohler's disease (Smillie's classification grade III-V) were operated between May 1996 to December 2011. Read More

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http://dx.doi.org/10.1016/j.fas.2018.02.013DOI Listing
February 2018
3 Reads

[Double Blockade of Aldosterone Receptors as a Method of Elimination Negative Effects of Non-Steroidal Anti-Inflammatory Drugs in Chronic Heart Failure].

Kardiologiia 2018 09;58(9):96-100

Federal State Budgetary Educational Institution of Higher Education "Rostov State Medical University" of the Ministry of Health of the Russian Federation.

The article deals with the dynamics of echocardioscopy indices during 1.5 years in a patient who underwent an acute myocardial infarction (MI). Two months after the MI left ventricular (LV) end-diastolic size and LV volume were 61 mm and 190 ml, respectively; LV ejection fraction (EF) was 42%. Read More

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September 2018
5 Reads

Intra-articular Large Ossicle Associated to Osgood-Schlatter Disease.

Cureus 2018 Jul 19;10(7):e3008. Epub 2018 Jul 19.

Orthopaedic Surgery, CHA University, Seongnam, KOR.

Osgood-Schlatter disease (OSD) is known as a self-limiting condition but surgical excision of the ossicles may be required in adults resistant to conservative treatments. The ossicle associated to OSD is generally small and located outside the joint near the tibial tubercle; however, large or intra-articular ossicle has been reported rarely. Here, we report an unusual case of OSD with a separated, large-sized ossicle that protruded into the knee joint and treated by arthroscopy-assisted excision of the ossicle. Read More

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https://www.cureus.com/articles/13563-intra-articular-large-
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http://dx.doi.org/10.7759/cureus.3008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145751PMC
July 2018
7 Reads

Juvenile osteochondritis dissecans of the knee is a result of failure of the blood supply to growth cartilage and osteochondrosis.

Osteoarthritis Cartilage 2018 Dec 21;26(12):1691-1698. Epub 2018 Sep 21.

Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA. Electronic address:

Objective: Juvenile osteochondritis dissecans (JOCD) is similar to osteochondrosis dissecans (OCD) in animals, which is the result of failure of the cartilage canal blood supply, ischemic chondronecrosis and delayed ossification, or osteochondrosis. The aim of the current study was to determine if osteochondrosis lesions occur at predilection sites for JOCD in children.

Method: Computed tomographic (CT) scans of 23 knees (13 right, 10 left) from 13 children (9 male, 4 female; 1 month to 11 years old) were evaluated for lesions consisting of focal, sharply demarcated, uniformly hypodense defects in the ossification front. Read More

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http://dx.doi.org/10.1016/j.joca.2018.06.019DOI Listing
December 2018
5 Reads

Acute presentation of Sinding-Larsen-Johansson disease simulating patella sleeve fracture: A case report.

Authors:
Nabil Alassaf

SAGE Open Med Case Rep 2018 10;6:2050313X18799242. Epub 2018 Sep 10.

Department of Surgical Specialties, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia.

Objectives: Diagnosis of Sinding-Larsen-Johansson disease may not be an easy task. Several sport-related conditions affect the distal pole of the patella in the adolescent, and treatment varies considerably. The article describes a patient that had radiographic features of Sinding-Larsen-Johansson disease associated with an atypical acute presentation. Read More

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http://journals.sagepub.com/doi/10.1177/2050313X18799242
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http://dx.doi.org/10.1177/2050313X18799242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131294PMC
September 2018
4 Reads

Pathogenic Factors Associated With Osgood-Schlatter Disease in Adolescent Male Soccer Players: A Prospective Cohort Study.

Orthop J Sports Med 2018 Aug 28;6(8):2325967118792192. Epub 2018 Aug 28.

Department of Rehabilitation, School of Allied Health Sciences, Kitasato University, Sagamihara, Japan.

Background: A previous cross-sectional study reported that pathogenic factors associated with Osgood-Schlatter disease (OSD) in adolescent athletes include increased quadriceps muscle tightness, lower leg malalignment, and development of apophysitis in the tibial tuberosity.

Purpose: To confirm these pathogenic factors associated with OSD in a longitudinal study with regard to physical function and performance.

Study Design: Cohort study; Level of evidence, 2. Read More

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http://journals.sagepub.com/doi/10.1177/2325967118792192
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http://dx.doi.org/10.1177/2325967118792192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113738PMC
August 2018
7 Reads

Therapeutic interventions in children and adolescents with patellar tendon related pain: a systematic review.

BMJ Open Sport Exerc Med 2018 13;4(1):e000383. Epub 2018 Aug 13.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), Botnar Research Centre, University of Oxford, Oxford, UK.

Objective: Evaluate effectiveness and harms of interventions for patellar tendon related pain in children and adolescents.

Design: Systematic review and meta-analysis.

Data Sources: Medline via Pubmed, Embase via OVID, CINAHL via Ebsco, SportDiscus up until 24 November 2017 were searched. Read More

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http://bmjopensem.bmj.com/lookup/doi/10.1136/bmjsem-2018-000
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http://dx.doi.org/10.1136/bmjsem-2018-000383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109948PMC
August 2018
7 Reads

Polymorphisms in selected genes and analysis of their relationship with osteochondrosis in Polish sport horse breeds.

Anim Genet 2018 Dec 28;49(6):623-627. Epub 2018 Aug 28.

Institute of Genetics and Animal Breeding of the Polish Academy of Science in Jastrzebiec, Postepu Street 36A, 05-552, Magdalenka, Poland.

The aim of this research was to evaluate the polymorphisms of selected genes and to find their potential effect on the occurrence of osteochondrosis in Polish Warmbloods (sport horse breeds). The study was conducted on a group of 198 horses subjected to official performance tests. Investigated joints-fetlock, hock and stifle-were X-rayed twice, once before and again at the end of the tests (first and second examination), and on this basis the degree of disease was evaluated. Read More

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http://dx.doi.org/10.1111/age.12715DOI Listing
December 2018
6 Reads

Opening Wedge Osteotomy for the Correction of Adolescent Tibia Vara.

Iowa Orthop J 2018 ;38:141-146

University of Alabama.

Background: Tibia vara, or Blount's disease, is a pathologic angular deformity of upper tibial physis causing a bow leg deformity. Adolescent Blount's disease may be unilateral or bilateral and is diagnosed during or just before the adolescent growth spurt. In addition to predisposing genetic factors, biomechanical overload of the proximal tibial physis causes asymmetric growth leading to a varus deformity. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047391PMC
December 2018
15 Reads

Incidence and characteristics of juvenile tarsocrural osteochondrosis in purebred Angus bulls.

Vet J 2018 07 21;237:34-36. Epub 2018 May 21.

Department of Environmental Health and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 300 W. Drake Rd., Campus Delivery 1620, Fort Collins, CO 80523-1620, USA. Electronic address:

Osteochondrosis (OC) of the bovine tarsus has been suggested to contribute to osteoarthritis. The objective of this prospective cohort study was to provide data specific to the Angus breed. Clinical and radiographic exams evaluating OC lesions, effusion and osteoarthritis were performed in 50 purebred bull calves at three time points between 5. Read More

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http://dx.doi.org/10.1016/j.tvjl.2018.05.006DOI Listing
July 2018
3 Reads

Headache in transient ischemic attacks.

J Headache Pain 2018 Jul 27;19(1):60. Epub 2018 Jul 27.

Danish Headache Center, Department of Neurology, Rigshospitalet-Glostrup, University of Copenhagen, Copenhagen, Denmark.

Background: Headache is a common feature in acute cerebrovascular disease but no studies have evaluated the prevalence of specific headache types in patients with transient ischemic attacks (TIA). The purpose of the present study was to analyze all headaches within the last year and the last week before TIA and at the time of TIA.

Methods: Eligible patients with TIA (n = 120, mean age 56. Read More

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http://dx.doi.org/10.1186/s10194-018-0888-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063808PMC
July 2018
25 Reads

Arthroscopic Management of Osteochondrosis of the Glenoid Cavity in a Dog.

J Am Anim Hosp Assoc 2018 Sep/Oct;54(5):e54503. Epub 2018 Jul 24.

From Ecole Nationale Vétérinaire de Toulouse, Toulouse, France.

A 5 mo old English setter dog was presented with mild left forelimb lameness. Physical examination revealed pain upon shoulder palpation and extension. Mediolateral radiographs of both shoulders showed a subchondral bone defect in the mid-portion of the glenoid cavity. Read More

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http://dx.doi.org/10.5326/JAAHA-MS-6584DOI Listing
November 2018
9 Reads

Pediatric Pain Syndromes and Noninflammatory Musculoskeletal Pain.

Pediatr Clin North Am 2018 08;65(4):801-826

Research Institute, Child Health Evaluative Sciences, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.

Chronic musculoskeletal pain (CMP) is one of the main reasons for referral to a pediatric rheumatologist and is the third most common cause of chronic pain in children and adolescents. Causes of CMP include amplified musculoskeletal pain, benign limb pain of childhood, hypermobility, overuse syndromes, and back pain. CMP can negatively affect physical, social, academic, and psychological function so it is essential that clinicians know how to diagnose and treat these conditions. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.04.004DOI Listing
August 2018
4 Reads

ALIF L5/S1 in adolescent patient with osteochondrosis.

Authors:
Max Aebi

Eur Spine J 2018 07;27(Suppl 4):561-562

das Rückenzentrum, Salem-Spital Hirslanden, Bern, Switzerland.

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http://link.springer.com/10.1007/s00586-018-5690-1
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http://dx.doi.org/10.1007/s00586-018-5690-1DOI Listing
July 2018
7 Reads

Expression of pro-apoptotic markers is increased along the osteochondral junction in naturally occurring osteochondrosis.

Bone Rep 2018 Dec 21;9:19-26. Epub 2018 Jun 21.

Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331, USA.

Osteochondrosis (OC) is a naturally occurring disease of the articular-epiphyseal cartilage and subchondral bone layers, leading to pain and decreased mobility. The objective of this study was to characterize gene and protein expression of apoptotic markers in chondrocytes surrounding cartilage canals and along the osteochondral junction of osteochondrosis (OC)-affected and normal cartilage, using naturally occurring disease in horses. Paraffin-embedded osteochondral samples (6 OC, 8 normal controls) and cDNA from chondrocytes captured with laser capture microdissection (4 OC, 6 normal controls) were obtained from the lateral trochlear ridge of femoropatellar joints in 14 immature horses (1-6 months of age). Read More

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http://dx.doi.org/10.1016/j.bonr.2018.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038796PMC
December 2018
38 Reads

Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies.

J Proteome Res 2018 08 20;17(8):2735-2743. Epub 2018 Jul 20.

Institute of Veterinary Science , University of Liverpool , Leahurst Campus , Neson CH64 7TE , U.K.

Osteoarthritis (OA), osteochondrosis (OC), and synovial sepsis in horses cause loss of function and pain. Reliable biomarkers are required to achieve accurate and rapid diagnosis, with synovial fluid (SF) holding a unique source of biochemical information. Nuclear magnetic resonance (NMR) spectroscopy allows global metabolite analysis of a small volume of SF, with minimal sample preprocessing using a noninvasive and nondestructive method. Read More

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http://dx.doi.org/10.1021/acs.jproteome.8b00190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092013PMC
August 2018
38 Reads

Fifty years of osteochondrosis.

Authors:
René van Weeren

Equine Vet J 2018 Sep 29;50(5):554-555. Epub 2018 Jun 29.

Department of Equine Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/evj.12821DOI Listing
September 2018
3 Reads

Ossification of the Ligamentum Flavum in a Nineteenth-Century Skeletal Population Sample from Ireland: Using Bioarchaeology to Reveal a Neglected Spine Pathology.

Sci Rep 2018 Jun 18;8(1):9313. Epub 2018 Jun 18.

Department of Anatomy, University of Otago, Dunedin, New Zealand.

Ossification of the ligamentum flavum of the spine (OLF) is rarely reported in individuals of European ancestry. It has, however, been observed in archaeological skeletons from Europe. The aim of this study was to revisit OLF rates, utilising a mid-nineteenth-century skeletal sample from Ireland. Read More

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http://dx.doi.org/10.1038/s41598-018-27522-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006438PMC
June 2018
3 Reads

Treatment failures and complications in patients with Blount disease treated with temporary hemiepiphysiodesis: a critical systematic literature review.

J Pediatr Orthop B 2018 Nov;27(6):522-529

Department of Orthopaedics, University Medical Center Hamburg-Eppendorf.

This systematic review sums up the state of knowledge about complications and reasons for failure when children with Blount disease are treated with temporary hemiepiphysiodesis. Twelve studies meet the inclusion criteria. The main reported obstacles were under correction and the poor predictability of the amount of correction that was obtainable. Read More

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http://Insights.ovid.com/crossref?an=01202412-201811000-0000
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http://dx.doi.org/10.1097/BPB.0000000000000523DOI Listing
November 2018
31 Reads

[Gauthier's osteotomy and fixation using osteosuture in the treatment of Freiberg's disease].

Pan Afr Med J 2018 16;29:33. Epub 2018 Jan 16.

Service de Traumato-orthopédie du CHU Mohammed VI, Oujda, Maroc.

Freiberg's disease is an osteochondrosis of the metatarsal heads mainly affecting the second metatarsal head. This study was conducted over a 3 year period. It reports 6 cases of patients, whose average age was 19. Read More

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http://dx.doi.org/10.11604/pamj.2018.29.33.8383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987133PMC
June 2018
11 Reads