406 results match your criteria Orvosi hetilap[Journal]


[A clinicopathological retrospective epidemiological analysis of benign tumors and tumor-like lesions in the oral and maxillofacial region, diagnosed at the University of Szeged, Department of Oral Medicine (1960-2014)].

Orv Hetil 2018 Sep;159(37):1516-1524

Fogorvostudományi Kar, Szájsebészeti Tanszék, Szegedi Tudományegyetem Szeged.

Introduction: In a clinicopathological retrospective epidemiological study we investigated benign tumors and tumor-like lesions located in the orofacial region, diagnosed at the Universiy of Szeged, Department of Oral Medicine.

Method: During a 54-year period (1960-2014), 14 661 biopsies were taken. The included subjects were 7491 patients diagnosed with benign tumors and tumor-like lesions. Read More

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September 2018
9 Reads

[Sarcopenia and quality of life: the validated Hungarian translation of the Sarcopenia Quality of Life (SarQoL) questionnaire].

Orv Hetil 2018 Sep;159(36):1483-1486

Marosvásárhelyi Orvosi és Gyógyszerészeti Egyetem Marosvásárhely (Târgu Mureș, Románia).

Introduction: Sarcopenia, or age-related muscle loss, is emerging as a serious public health concern. Due to the impaired physical performance associated with sarcopenia, a reduced quality of life (QoL) has been evidenced in the affected individuals. Generic instruments, such as Rand Corporation Short Form 36 (SF-36) or the European Quality of Life (EuroQoL-5D) questionnaires do not accurately assess the impact of sarcopenia on QoL. Read More

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September 2018

[The medical psychology in Hungary: way of thinking, frame of references and applications].

Orv Hetil 2018 Sep;159(36):1455-1464

Magatartástudományi Intézet, Debreceni Egyetem, Népegészségügyi Kar Debrecen.

The present study aims at overviewing the different stages of the education of medical psychology in Hungary. In the perspective of the achievements of cognitive and affective neuroscience as well as developmental psychology, we intend to define the roots of doctor-patient relationship, certain determining factors of diagnosis forming and therapy efficiency as well as the essential components of empathy. We attest to the fact that the current psychosomatic medicine with its evidence-based achievements is a valid component and constitutive pillar of everyday medical care. Read More

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September 2018

[Hungarian clinical application opportunities of PET/MR imaging and first experiences].

Orv Hetil 2018 Aug;159(34):1375-1384

Egészségügyi Központ, Diagnosztikai és Onkoradiológiai Intézet, Kaposvári Egyetem Kaposvár, Guba S. u. 40., 7400.

Hungary's first and still only multimodality PET/MR device is operating in the Health Center of Kaposvár University. The aim of our review article is to present the current Hungarian PET/MR imaging application opportunities, our available initial experiences with this novel multimodality imaging technique in malignant and non-malignant diseases and further potential targeted clinical fields of use are also addressed. Orv Hetil. Read More

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August 2018
16 Reads

[Diabetes mellitus: endothelial dysfunction and changes in hemostasis].

Orv Hetil 2018 Aug;159(33):1335-1345

Aneszteziológiai és Intenzív Terápiás Intézet, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged, Semmelweis u. 6., 6720.

Diabetes mellitus involves a group of chronic metabolic disorders with elevated blood glucose concentrations. Since this disease needs lifelong treatment and care, the medical and social aspects present major public health concerns and pose a global challenge for health care providers. The number of aged patients with degenerative diseases undergoing surgical procedures is continuously increasing, resulting in an overwhelming dominance of diabetes in the perioperative care. Read More

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[Investigation of the genetic background of complex diseases].

Orv Hetil 2018 Aug;159(31):1254-1261

II. Belgyógyászati Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.

Although the Human Genome Project discovered the sequence of the human genetic information 15 years ago, genetic background of the diseases - primarily that of complex disorders - is still not known. The sum of the not yet discovered inherited risk factors is termed the missing heritability; the identification of these genetic components is, however, essential, as it is the base of the understanding of the molecular pathomechanism of diseases. It is not only of theoretical importance: this knowledge can be used in the clinical practice, as it offers the possibility of improvement of diagnostics, prevention as well as targeted and individualized therapy. Read More

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August 2018
1 Read

[Citation analysis of the Hungarian-language Orvosi Hetilap based on indicators between 2012 and 2016].

Orv Hetil 2018 Jul;159(30):1226-1234

Központi Könyvtár, Semmelweis Egyetem Budapest, Üllői út 26., 1085.

Introduction: After getting indexed by scientific databases - Web of Science, Journal Citation Reports - the obtained scientific performance of the journal needs to be kept up.

Aim: The aim of this article is to analyse citation numbers based on different bibliometric indicators between 2012 and 2016 comparing data with an article published in 2012.

Method: Authors evaluated issues of Orvosi Hetilap published in 2013-2015 and searched data in various international databases. Read More

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[Dental morphological and metric characteristics in contemporary and historical population of Târgu Mureș].

Orv Hetil 2018 Jul;159(30):1235-1240

Maros Megyei Múzeum Marosvásárhely (Târgu Mureș), Románia.

Introduction: Teeth, as an integral part of human organism, are not exceptions from the physical anthropology changes caused by biological evolution and the way of living. Different stress factors and the natural selection are contributing to the emphasis of certain morphological characteristics.

Aim: Comparison of dental metric characteristics and the presence of accessory tooth cusps between human remains from the Middle Ages and dental study models of today's patients. Read More

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July 2018
4 Reads

[Potential relationship between juice cleanse diets and eating disorders. A qualitative pilot study].

Orv Hetil 2018 Jul;159(28):1153-1157

Magatartástudományi Intézet, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Nagyvárad tér 4., 1089.

Introduction And Aim: There are two notable eating behaviors that are not far from having their own category as a mental disorder: the purging disorder, that is already among the DSM-5 non-specific eating disorders, and orthorexia nervosa, when a person is fixating too much on healthy foods. Our purpose is to describe how these can be observed in recreational juice cleanse camps, which are very popular today as an alternative health trend.

Method: The first author recorded her data during multisited ethnographic observations in two Hungarian juice cleanse camps. Read More

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July 2018
10 Reads

[Semmelweis - a contemplating human. Scientific historical lessons].

Authors:
István Gazda

Orv Hetil 2018 Jul;159(26):1055-1064

Magyar Tudománytörténeti és Egészségtudományi Intézet Budapest, Bem József u. 8., 1027.

In this article we examine why Semmelweis's seemingly simple, logical and practical discovery was categorically dismissed by the majority of his contemporaries, and why even many years after his death it was accepted with such reservation. We invoke wherever possible Semmelweis's own words citing from the series of articles appearing in the 'Orvosi Hetilap' [Hungarian Medical Weekly Journal] published in 1858 in Hungary, and also from the German language summary of the Journal published in 1860. We came to the conclusion that although Semmelweis did everything in his power to show the causal relationship between the development of puerperal fever (childbed fever) and some infectious substance on the hands of examining doctors and medical students, this was not convincing enough. Read More

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[Ignác Semmelweis and the Hungarian Medical Weekly Journal].

Authors:
László Kiss

Orv Hetil 2018 Jul;159(26):1065-1070

Szent Erzsébet Egészségügyi és Szociális Munka Főiskola Pozsony (Bratislava, Szlovákia).

Ignác Semmelweis did not publish his discovery in Vienna - i.e., that the puerperal fever may be prevented by careful washing of the hand in chlorine solution (asepsis) - for ten years. Read More

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Markusovszky Lajos-emlékülés a nagy magyar orvos halálának 125. évfordulóján. Budapest, 2018. május 3.

Authors:

Orv Hetil 2018 Jul;159(26):1086-1091

Természettudományi és Orvostudományi Szerkesztőség, Akadémiai Kiadó Zrt., 1117 Budapest, Budafoki út 187-189. A épület, III. emelet www.orvosihetilap.com.

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[Relationship between patent foramen ovale and cryptogenic stroke in a retrospective hospital-based study].

Ideggyogy Sz 2018 May;71(5-06):169-177

Magyar Honvédség Egészségügyi Központ, Neurológiai Osztály, Budapest, Magyarország.

Background And Purpose: After routine workup, 23-25% of ischemic strokes etiology remains unknown, i.e. cryptogenic. Read More

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May 2018
3 Reads

[Bicentennial of catalase research, 1818-2018].

Authors:
László Góth

Orv Hetil 2018 Jun;159(24):959-964

Orvosi Laboratóriumi és Képalkotó Diagnosztikai Tanszék, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4012.

L. J. Thénard and J. Read More

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[Is second-line immunomodulatory treatment effective in multiple sclerosis?]

Ideggyogy Sz 2017 Jul;70(7-8):275-283

Debreceni Egyetem, Általános Orvostudományi Kar, Neurológiai Tanszék, Debrecen.

Background And Purpose: Natalizumab is the first evidence based monoclonal antibody, which was launched for treatment in relapsing remitting multiple sclerosis in Hungary in 2010. Standardized follow-up is required to use it.

Methods: Our aim was to evaluate the efficacy and to monitor the safety of natalizumab treatment by using an electronic database established for MS registry. Read More

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July 2017
10 Reads

[Diabetes, dementia, depression, distress].

Ideggyogy Sz 2017 Sep;70(9-10):293-299

University of East Anglia, Faculty of Medicine and Health Sciences, Norwich, UK.

The number of people living with diabetes continues to rise. Therefore neurologists or other health care practitioners may be increasingly faced with comorbid neuropsychiatric disorders commonly presented by diabetic patients. More recently there has been an increasing research interest not only in the interactions between diabetes and the nervous system, the fine structure and functional changes of the brain, but also in the cognitive aspects of antidiabetic treatments. Read More

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September 2017
2 Reads

[Preemptive and preventive analgesia - an important element in perioperative pain management].

Orv Hetil 2018 Apr;159(17):655-660

Aneszteziológiai és Intenzív Terápiás Klinika, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4032.

In this review, the definition and history of preemptive analgesia and the progress of its conception will be summarized. In the physiology-pathophysiology chapter, central sensitization, the key component of the evolution of postoperative pain, and the neurochemical processes in its background will be explored. Tissue damage caused by surgical incision consists of mechanical and inflammatory components, and it has high importance in the postoperative pain management. Read More

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April 2018
2 Reads

[Genetic heterogeneity and complexity of congenital heart defects].

Orv Hetil 2018 Apr;159(17):661-670

Orvosi Genetikai Intézet, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged, Somogyi B. u. 4., 6720.

Congenital heart defects are the most common birth defects, they account for approximately one third of all cases. They are clinically heterogeneous, vary widely in severity, treatability and prognosis and may occur as part of multiple developmental disorders, such as chromosome aberrations, microdeletion syndromes and monogenic diseases, or as isolated defects. Syndromic forms account for 25-40%, isolated forms for 60-75% of all cases. Read More

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April 2018
1 Read

[Immunoadsorption in a patient with dilated cardiomyopathy. The first case in Hungary].

Orv Hetil 2018 Apr;159(13):526-530

Kardiológiai Intézet, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen.

Dilated cardiomyopathy is the main cause of heart transplantation. The etiology is unknown in almost half of the cases. Many cardiac specific antibodies have been identified till now which can cause decreased cardiac function, ventricular tachycardia or sudden heart death. Read More

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April 2018
4 Reads

[The situation of pediatric patients' rights in the Transylvanian healthcare].

Orv Hetil 2018 Mar;159(11):423-429

Humántudományi Tanszék, Partiumi Keresztény Egyetem, Gazdaság és Társadalomtudományi Kar Oradea, Str. Dunării nr. 12/8, 410027 jud. Bihor, Románia.

This study summarizes the results of the author's PhD thesis presenting the research process and the most important findings regarding the situation of Transylvanian healthcare. Our data are based on the knowledge and compliance of pediatric patients' rights as they are seen by healthcare specialists, parents and children. A number of 751 persons were involved in the research: 200 healthcare specialists, 200 parents, 200 children aged from 7 to 17 years who have been experiencing health services at least three times over the past year and a control group of 151 children who did not have this kind of experience. Read More

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March 2018
1 Read

[Objective evaluation of orthodontic treatment need with Dental Aesthetic Index].

Orv Hetil 2018 Mar;159(9):352-356

Faculty of Dental Medicine, Victor Babes University of Medicine and Pharmacy Timisoara, Romania.

Introduction And Aim: To evaluate the frequency and severity of the malocclusions and treatment need in a group of adult patients in Târgu-Mureș, dividing them up according to age and gender.

Method: Sixty-four, randomly selected patients were divided up according to age and gender. Ten occlusal traits related to dentofacial anomalies according to missing teeth, spacing, crowding and occlusion were used to evaluate the malocclusions on each of their study cast. Read More

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March 2018
2 Reads

[Autoimmune encephalitis: possibilities in the laboratory investigation].

Orv Hetil 2018 Jan;159(3):107-112

Klinikai Központ, Immunológiai és Biotechnológiai Intézet, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs, Szigeti út 12., 7624.

Introduction: The role of autoimmune responses against central nervous system (CNS) antigens in encephalitis presenting with non-classified neurologic or psychiatric symptoms has been appreciated in the past decade. Paraneoplastic limbic encephalitis has a poor prognosis and is most commonly associated with lung, ovarium, and testicular neoplasms, leading to immune reactions against intracellular antigens (anti-Hu/ANNA1, anti-Ri/ANNA2, anti-CV2/CRMP5 and anti-Ma2/Ta). In contrast, the recently described autoimmune encephalitis subtypes present with a broad spectrum of symptoms, respond to autoimmune therapies well and usually associate with autoantibodies against neuronal cell surface receptors (NMDAR, GABAR, AMPAR) or synaptic proteins (LGI1, CASPR2). Read More

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January 2018
3 Reads

[The role of selective monoamine oxidase B inhibitors in the therapeutic strategy of Parkinson's disease in the neurology clinics of Tirgu Mures County Emergency Clinical Hospital].

Orv Hetil 2017 Dec;158(51):2023-2028

Neurológiai Tanszék (Department of Neurology), Marosvásárhelyi Orvosi és Gyógyszerészeti Egyetem (University of Medicine and Pharmacy of Tirgu Mures) 540081 Marosvásárhely (Tirgu Mures), Gral Ion Dumitrache u. 20/2, Románia.

Introduction: Selective monoamine oxidase B inhibitors have an accurate place in therapeutical strategy of Parkinsons's disease. In the early stages of the disease, especially in younger patients with milder symptoms, the introduction of levodopa substitution could be efficacious in delaying; in advanced stages they are mainly used to treat motor complications, as an adjunct to levodopa.

Aim: The evaluation of therapeutical strategies used in the neurology clinics of Tirgu Mures County Emergency Clinical Hospital in order to define the role of monoamine oxidase B inhibitors. Read More

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December 2017
2 Reads

[Rhabdomyolysis - may it be a metabolic myopathy? Case report and diagnostic algorithm].

Orv Hetil 2017 Nov;158(47):1873-1882

I. Gyermekgyógyászati Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.

We report the case of a 46-year-old female patient with recurrent rhabdomyolysis. In the background of her metabolic myopathy an inherited metabolic disorder of the fatty acid oxidation, very long-chain acyl-coenzyme A-dehydrogenase deficiency was diagnosed. The diagnosis was based on abnormal acyl-carnitine- and urine organic-acid profile in addition to low residual enzyme activity, and was confirmed by genetic testing. Read More

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November 2017
26 Reads

[Validation of Hungarian Smartphone Deprivation Inventory (HSDI) with school children].

Psychiatr Hung 2017 ;32(3):307-312

Marosvasarhelyi Orvosi és Gyogyszereszeti Egyetem, Orvostudomanyok Kar, Etika es Tarsadalomtudomanyok Tanszek, Marosvasarhely, Romania. E-mail:

The widespread use of smartphones generates new habits and behaviors among the users, including schoolchildren. Advance technology-based applications, capturing interest and attention, influence cognitive focus and time spent with the device. Examination of these factors points toward the risk of addiction, as well as the deprivations sensations associated with the latter, that call for scholastic attention. Read More

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January 2017

[Study of socio-demographic factors in the treatment of unipolar major depression in a follow-up clinical trial].

Orv Hetil 2017 Oct;158(43):1715-1722

Pszichiátria Tanszék, Marosvásárhelyi Orvosi és Gyógyszerészeti Egyetem Marosvásárhely, Románia.

Introduction: Depression is one of the most widespread illnesses of our time, currently affecting more than 300 million people worldwide. Literature identifies several socio-demographic risk factors in the development of the depression.

Aim: We aim to examine the socio-demographic factors involved in the remission of clinically diagnosed unipolar major depression. Read More

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October 2017
1 Read

[Study of the canalis mandibulae morphology in different vertical facial types].

Orv Hetil 2017 Nov;158(46):1841-1847

Fogorvosi Kar, Fogmorfológia és Anyagtan Tanszék, Marosvásárhelyi Orvosi és Gyógyszerészeti Egyetem Marosvásárhely.

Introduction: The precise knowledge of the position of canalis mandibulae and foramen mandibulae is important for surgical and endodontic interventions on the mandible.

Aim: The aim of the study is to examine the position of these anatomical landmarks in different vertical facial types.

Method: In the panorama radiograph of 26 normodivergent, 26 hypodivergent and 28 hyperdivergent arthritis (total of 1360 measurements) we measured the distance between the canalis mandibulae and interdental septums, the apex of the lateral teeth, the mandibular base, the goniac angle, and the steepness of the canal and the distance the foramen mandibulae to the anterior and posterior margin of the ramus. Read More

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November 2017
1 Read

[Telecardiology: Tasks and duties of telemedicine].

Orv Hetil 2017 Nov;158(44):1741-1746

Orvosi Fizikai és Orvosi Informatikai Intézet, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged.

Telemedicine is a young science that integrates innovations of information-technology and telecommunications into medical science. A successful telemedicine procedure should guarantee reduced workload of the healthcare system with well secured and cost-effective processes. Our goal was to collect the development phases of telemedicine projects through existing telecardiology solutions. Read More

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November 2017
3 Reads

[Experimental study on the resistance to intraluminal pressure between handsewn and stapled anastomosis. In vitro experimental study].

Orv Hetil 2017 Oct;158(42):1674-1680

Sebészeti Tanszék, Marosvásárhelyi Orvosi és Gyógyszerészeti Egyetem Gheorghe Marinescu nr 1, Marosvásárhely.

Intoduction and aim: The aim of the study was to compare the resistance to pressure of stapled and manually handsewn intestinal suture lines on in vitro pig intestine model.

Method: We performed different types of stapled and manual sutures and the pressure level was measured using a differential pressure manometer.

Results: Although the hand-sewn end-to-end suture turned out to be the most resistant to pressure, statistical analysis revealed no significant differences compared to stapled suture (p = 0. Read More

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October 2017
3 Reads

[Efficacy of the population-based pilot colorectal screening program. Hungary, Csongrád county, 2015].

Orv Hetil 2017 Oct;158(42):1658-1667

I. Belgyógyászati Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged, Korányi fasor 8., 6720.

Introduction: In Hungary, a nationwide colorectal screening program is about to be introduced in order to improve the extremely high mortality rate of colorectal cancer (CRC).

Aim: The aim of our study was to summarize experiences and assess short-term efficacy of the population-based pilot colorectal screening program in 2015 in Csongrád County, Hungary.

Patients And Method: Asymptomatic individuals between the ages of 50 and 70 with average risk of colorectal cancer participated in the program that was based on the two-step screening method (i. Read More

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October 2017
14 Reads

[Neuroacanthocytosis diagnosis with new generation whole exome sequencing].

Orv Hetil 2017 Oct;158(42):1681-1684

Klinikai Központ, Orvosi Genetikai Intézet, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs, József A. u. 7., 7623.

In a patient with marked symptoms of Huntington disease after the huntingtin testing, which gave normal result, a whole exome sequencing (WES) has been performed based on an international collaboration. A homozygous G>A nucleotid change in the exon 34 of the VPS13A gene has been detected with WES, a mutation resulting in a premature stop codon at the position 1301. This change is a known pathogenic mutation. Read More

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October 2017
13 Reads

[Why would doctors from Debrecen go abroad? Results of a questionnaire].

Orv Hetil 2017 Sep;158(37):1458-1468

Orvosi Képalkotó Intézet, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen.

Introduction: Numerous beliefs have arisen in relation to the emigration of doctors. First of all, in most cases emigration has been attributed to, almost exclusively, low salaries. There are a number of non-financial issues that could possibly be more easily addressed. Read More

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September 2017
8 Reads

[Evaluation of anatomic and prognostic stages of breast cancer according to the 8th edition of the TNM staging system - Retrospective analysis based on data from deceased patients once diagnosed with breast cancer].

Orv Hetil 2017 Sep;158(35):1373-1381

Általános Orvostudományi Kar, Patológiai Intézet, Szegedi Tudományegyetem Szeged, Állomás u. 1., 6725.

Introduction: The 8th edition of the Tumor-Node-Metastasis (TNM) based staging of breast cancer introduces a prognostic stage influenced by biomarkers along the traditional T, N and M categories.

Aim: To retrospectively assess stage influencing prognostic variables; and the anatomic and prognostic stages on the basis of the overall survival (OS) of a cohort of deceased patients once diagnosed with breast cancer.

Method: We included patients with known causes of death certified at the Bács-Kiskun County Teaching Hospital and having a history of breast cancer diagnosed on a resection specimen at the same institution. Read More

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September 2017
14 Reads

[Pre-programmed genes].

Authors:
János Szabad

Orv Hetil 2017 Aug;158(34):1323-1330

Orvosi Biológiai Intézet, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged, Somogyi u. 4., 6720.

Cells feel good and carry on perfect functions when they contain the right types of proteins in the right concentration, at the right time and sites. There are mechanisms that ensure the right level of gene expression in the different cell types: the formation of protein molecules based on the DNA-encoded genetic information. Gene expression can also be regulated through the compactness of chromatin, i. Read More

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August 2017
2 Reads

[Effectiveness of mindfulness-based cancer recovery (MBCR) program among Hungarian cancer patients].

Orv Hetil 2017 Aug;158(33):1293-1301

Egészségtudományi Kar, Egészségbiztosítási Intézet, Pécsi Tudományegyetem Pécs.

Introduction And Aim: Employment of mindfulness-based programs and techniques in the treatment of cancer patients have spread exponentially in the past decade. A large number of studies have proved the effectiveness of the program in the reduction of stress symptoms, depression and anxiety, and the improvement of sleep and mood patterns. The present study was done at Firebird Foundation and examines the effectiveness of the complex, MBCR (mindfulness-based cancer recovery)-based psycho-social intervention in the treatment of cancer patients. Read More

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August 2017
25 Reads

[Importance of gross deletions in the diagnosis of tuberous sclerosis complex: the first Hungarian cases].

Orv Hetil 2017 Jul;158(30):1188-1194

Klinikai Központ, Orvosi Genetikai Intézet, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs, Szigeti út 12., 7624.

Tuberous sclerosis complex is a rare disease with high phenotypic heterogeneity, characterized by the appearance of multiplex hamartomas in the different organs. The disease is inherited by autosomal dominant manner, due to the mutations of two genes: the TSC1 or the TSC2. In this publication we present the cases of two young male and two middle-aged female patients, where pathogenetic differences of TSC1/TSC2 could not be verified by Sanger sequencing. Read More

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July 2017
5 Reads

[Difficulties in communication with parents of pediatric cancer patients during the transition to palliative care].

Orv Hetil 2017 Jul;158(30):1175-1181

Magatartástudományi Intézet, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Nagyvárad tér 4., 1089.

Introduction: Adequate communication by medical personnel is especially important at certain points during the treatment of childhood cancer patients.

Aim: To investigate the timing and manner of communication with parents concerning the introduction of palliative care in pediatric oncology.

Method: Structured interviews, containing 14 questions, were carried out with physicians working in pediatric oncology (n = 22). Read More

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July 2017
23 Reads

[Examination of placental three-dimensional power Doppler indices and perinatal outcome in pregnancies complicated by intrauterine growth restriction].

Orv Hetil 2017 Jul;158(26):1008-1013

Általános Orvostudományi Kar, Szülészeti és Nőgyógyászati Klinika, Szegedi Tudományegyetem Szeged, Semmelweis u. 1., 6725.

Introduction: Development of intrauterine growth restriction (IUGR) can be traced back to maternal or fetal factors, but in many cases we find placental factors (reduced placental circulation) in the background.

Aim: Our aim was to examine whether the reduced placental bloodperfusion and vascularity show any correlation with cesarean section frequency and the clinical outcome in IUGR pregnancies. The aim of the present study was also to use a properly calibrated and reproducible method for evaluating placental blood flow, that can later be incorporated into the routine examination. Read More

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July 2017
29 Reads

[Traumatic asphyxia with permanent visual loss. Case report].

Orv Hetil 2017 Jun;158(22):864-868

I. Ortopédia-Traumatológia Tanszék, Marosvásárhelyi Orvosi és Gyógyszerészeti Egyetem Marosvásárhely.

Traumatic asphyxia is a rare condition that occurs after compressive thoracoabdominal trauma, which is characterized by subconjunctival hemorrhage, cervicofacial cyanosis, edema and petechiae. Serious life-threatening thoracic and abdominal injuries may coexist. After conservatory treatment in most cases complete recovery is achieved, but in isolated cases permanent neurological lesions may occur. Read More

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June 2017
4 Reads

[Early symptoms of childhood malignant diseases].

Orv Hetil 2017 May;158(21):829-834

Gyermekgyógyászat Tanszék, Marosvásárhelyi Orvosi és Gyógyszerészeti Egyetem 540139, Gheorghe Marinescu u. 38., Marosvásárhely, Románia.

Introduction: Childhood malignant diseases are rare in pediatric pathology. Early symptoms are not specific, fatigue, pallor, compression signs and bone marrow failure are often mentioned.

Aim: To summarize the most frequent early symptoms of childhood malignancies in order to help the physicians in the early recognition. Read More

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May 2017
21 Reads

[Investigating the efficacy of nutrition therapy for outpatients with inflammatory bowel disease].

Orv Hetil 2017 May;158(19):731-739

Általános Orvostudományi Kar, II. Belgyógyászati Klinika, Semmelweis Egyetem Budapest.

Introduction: Inflammatory bowel diseases can cause malnutrition (due to inflammatory cytokine production, catabolic states after surgery, restricted diet), which is difficult to treat by nutritional therapy.

Aim: Investigating the efficacy of nutrition therapy.

Method: Combined malnutrition risk screening (questionnaires and body composition analysis), at the beginning of the research and after a 1 year period. Read More

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May 2017
15 Reads

[Epidemiological data of Hungarian skiers' and snowboarders' medical problems].

Orv Hetil 2017 Apr;158(16):618-624

SOS Hungary Orvosi Szolgálat Budapest.

Introduction And Aim: There are no high mountains or any advantageous circumstances for winter sports in Hungary, yet within the 10 million population there are about half a million people (the exact number is 550,000) who tend to go for skiing or snowboarding abroad. Authors compared the injury statistical data with results described in the international literature in order to develop conclusions about the differences in the injury patterns and frequency between the Hungarian ones' and those found in countries with plenty of winter sport possibilities.

Method: Authors analysed the winter sport injury cases of an insurance company. Read More

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April 2017
2 Reads

[In memory of an excellent inventor and medical scientist. Aladár Felpéczi Petz (1888-1956)].

Orv Hetil 2017 Mar;158(12):472-476

Orvosi Könyvtár, Petz Aladár Megyei Oktató Kórház Győr.

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March 2017
5 Reads

[A8344G mitochondrial DNA mutation observed in two generations].

Orv Hetil 2017 Mar;158(12):468-471

Általános Orvostudományi Kar, Klinikai Központ, Orvosi Genetikai Intézet, Pécsi Tudományegyetem Pécs, József A. u. 7., 7623.

This article presents the case of a 62-year-old mother and her 41-year-old daughter, who have had severe neurological symptoms for a few decades. After a long investigation period the definite diagnosis of MERRF syndrome was confirmed. After DNA isolation from our patient's blood sample we examined the mitochondrial DNA with direct sequencing. Read More

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March 2017
7 Reads

[Effects of dietary monosodium-glutamate on gene expression].

Orv Hetil 2017 Mar;158(10):380-385

Orvosi Népegészségtani Intézet, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs.

Introduction: Nowadays, the food industry more often uses different type of additives during the food production.

Aim: Our aim was to examine the monosodium-glutamate's effect (in animal experiment) on DNA-methyltransferases in gene expression patterns of mRNA levels.

Materials And Method: In the investigation we used 24 (n=24) CD1 type female mice. Read More

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March 2017
16 Reads

[The safety of anti-diabetic drugs in heart failure].

Orv Hetil 2017 Feb;158(5):163-171

III. Belgyógyászati Tanszék, Marosvásárhelyi Orvosi és Gyógyszerészeti Egyetem (UMF Tg. Mureș) Marosvásárhely, Románia.

The association of diabetes and heart failure is very common, furthermore, the pathophysiology and clinical course of the two entities have many crossing-points. Today, the spectrum of available anti-diabetic drugs is extremely wide, ranging from the classical (insulin, biguanides, sulphonylureas) to the most recent agents (gliptins, gliflozins). The cardiovascular effects of these drugs are multiple, their knowledge is important in the everyday practice, as the use of safe drugs regarding of heart failure is preferred. Read More

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February 2017
17 Reads

[Application of password manager software in health care].

Authors:
József Ködmön

Orv Hetil 2016 Dec;157(52):2066-2073

Egészségügyi Informatikai Tanszék, Debreceni Egyetem, Egészségügyi Kar Nyíregyháza.

When using multiple IT systems, handling of passwords in a secure manner means a potential source of problem. The most frequent issues are choosing the appropriate length and complexity, and then remembering the strong passwords. Password manager software provides a good solution for this problem, while greatly increasing the security of sensitive medical data. Read More

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December 2016

[Factors influencing early detection of malignant melanoma].

Orv Hetil 2016 Dec;157(51):2028-2033

Bőrgyógyászati és Allergológiai Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged.

Introduction And Aim: Melanoma is a highly aggressive tumour with often unpredictable outcome. Our aim with this study was to determine factors influencing early detection of melanoma.

Method: We analyzed 139 questionnaires completed by patients diagnosed with melanoma. Read More

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December 2016
8 Reads