32,525 results match your criteria Organic Solvents


Micro-fabrication by Wax Spraying for Rapid Smartphone-Based Quantification of Bio-Markers.

Anal Biochem 2020 May 20:113777. Epub 2020 May 20.

Sensors and Integrated Biomicrofluidics/Mems Laboratory, School of Mechanical Engineering, Iran University of Science and Technology, 1684613114, Tehran, Iran; Sensors and Integrated Microsystems Laboratory, Mechanical and Mechatronics Engineering Department, University of Waterloo, ON, N2L 3G1, Waterloo, Canada. Electronic address:

A cheap/rapid technique for the fabrication of μPADs is presented for point of care analysis. Hydrophobic channels were formed across the width of the paper by spraying hot pure wax. This biocompatible novel process yielded uniform 300±5 μm hydrophilic microchannels on paper, without the use of the cleanroom, UV lamp, or organic solvents and was completed in a single step without the need for a hotplate. Read More

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http://dx.doi.org/10.1016/j.ab.2020.113777DOI Listing

Organic chemical characterization of size segregated particulate matter samples collected from a thermal power plant area.

Environ Pollut 2020 Jul 11;262:114360. Epub 2020 Mar 11.

Engineering Faculty, Department of Environmental Engineering, Eskişehir Technical University, Eskişehir, Turkey. Electronic address:

Kütahya city, a thermal power plant (TPPs) affected region of Turkey, has serious air quality problems like similar industrial regions of the world due to the emissions from three closely-located coal-fired TPPs, residential coal combustion along with the contribution of several industrial stacks. The organic chemical speciation of ambient size-segregated particulate matter (PM) was investigated during two seasons at two sites with different pollution characteristics (urban and rural). The ambient PM was collected using a high volume cascade impactor, with 6 stages: PM, PM, PM, PM, PM and PM. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.114360DOI Listing

Lipid peroxidation inhibition study: A promising case of 1,3-di([1,1'-biphenyl]-3-yl)urea.

Chem Biol Interact 2020 May 19:109137. Epub 2020 May 19.

Dipartimento di Scienze Biomediche e Cliniche "Luigi Sacco", Università degli Studi diMilano, Via G.B. Grassi 74, 20157, Milano, Italy. Electronic address:

In the present study eighteen inhibitors of the hydrolytic enzymes of the endocannabinoid system were investigated for antioxidant activity using lipid peroxidation (LP) method. Among the assayed compounds ten belong to carbamates with phenyl [1,1'-biphenyl]-3-ylcarbamate (6), reported for the first time, and eight are retro-amide derivatives of palmitamine. Interestingly, results indicated that most of the tested compounds have good antioxidant properties. Read More

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http://dx.doi.org/10.1016/j.cbi.2020.109137DOI Listing

Solvation Structures of Tetraethylammonium Bromide and Tetrafluoroborate in Aqueous Binary Solvents with Ethanol, Trifluoroethanol, and Acetonitrile.

J Phys Chem B 2020 May 22. Epub 2020 May 22.

The solvation structures of tetraethylammonium bromide and tetrafluoroborate (TEABr and TEABF) in aqueous binary solvents with ethanol (EtOH), 2,2,2-trifluoroethanol (TFE), and acetonitrile (AN) have been clarified by molecular dynamics (MD) simulations. In addition, H and C NMR chemical shifts of the H and C atoms within TEA in the binary solvents have been measured as a function of mole fraction of organic solvent, . The variations of the chemical shifts with the increase in was interpreted according to the solvation structures of TEA, Br, and BF obtained from the MD simulations. Read More

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http://dx.doi.org/10.1021/acs.jpcb.0c02586DOI Listing

An Easy Long-acting BMP7 Release System Based on Biopolymer Nanoparticles for Inducing Osteogenic Differentiation of Adipose Mesenchymal Stem Cells.

J Tissue Eng Regen Med 2020 May 22. Epub 2020 May 22.

Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.

In contrast to the early acting bone morphogenetic protein 2 (BMP2), bone morphogenetic protein 7 (BMP7) plays a decisive role mainly in the late stages of bone formation. To overcome deactivation and degradation of expensive BMP7, we designed a novel long-acting BMP7 release system based on poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P34HB) nanoparticles to enable the induction of osteogenic differentiation in human adipose mesenchymal stem cells (ADSCs). In order to improve the encapsulation efficiency of BMP7 and avoid damage by organic solvents, BMP7 was modified and protected using the biosurfactant soybean lecithin. Read More

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http://dx.doi.org/10.1002/term.3070DOI Listing

Biotransformation of poly(cis-1,4-isoprene) in a multiphase enzymatic reactor for continuous extraction of oligo-isoprenoid molecules.

N Biotechnol 2020 May 18. Epub 2020 May 18.

Institut of Molecular Microbiology and Biotechnology, University of Münster, D-48149 Münster, Germany; Environmental Sciences Department, King Abdulaziz University, Jeddah, Saudi Arabia.

Biotechnological processes for the partial degradation or transformation of poly(cis-1,4-isoprene) rubber have been investigated during recent decades with promising results. The use of the enzyme 'latex clearing protein' (Lcp) to transform the polymer into more hydrophilic oligo-isoprenoids results in modifications of the rubber structure and the synthesis of new material. In order to find an alternative process to recover the degradation products, a continuous extraction method using a biphasic system is described. Read More

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http://dx.doi.org/10.1016/j.nbt.2020.05.001DOI Listing

Fabrication of Deoxycholic Acid tethered α-Cyanostilbenes as Smart Low Molecular Weight Gelators and AIEE probes for Bio-imaging.

Steroids 2020 May 18:108659. Epub 2020 May 18.

Department of Chemistry, Birla Institute of Technology and Science, Pilani 333 031, Rajasthan, India. Electronic address:

Four novel deoxycholic acid tethered α-cyanostilbenes were designed, synthesized and characterized using detailed spectroscopic analysis. The synthesized deoxycholic acid tethered α-cyanostilbene derivatives formed stable gels with a variety of solvents, such as xylene, toluene, mesitylene, decane, dodecane etc. The stable gels showed lamellar sheet type structures stacked over each other, consisting of entangled fibres as evident from SEM, TEM and Fluorescence Microscopy images; The synthesized compounds exhibited AIEE behaviour in HO/THF mixture, with the maximum emission observed in 70% HO/THF fraction along with a bathochromic shift. Read More

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http://dx.doi.org/10.1016/j.steroids.2020.108659DOI Listing

In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations.

Eur J Pharm Biopharm 2020 May 18. Epub 2020 May 18.

Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway. Electronic address:

Melatonin is a neurohormone with potenial therapeutic effects in many diseases including neonatal hypoxic-ischemic (HI) brain injury. Due to limited solubility in water there is currently no clinically available melatonin formulation for parenteral use. Clinical use of melatonin has thus relied on oral administration, which in many cases is hampered by low and variable bioavailability. Read More

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http://dx.doi.org/10.1016/j.ejpb.2020.05.003DOI Listing

A facile route to transfer Cu nanoparticles to organic medium for better stabilization and improved photocatalytic activity towards N-formylation reaction.

Nanotechnology 2020 May 21. Epub 2020 May 21.

Department of Chemistry , University of Calcutta, Kolkata, West Bengal, INDIA.

Cu nanoparticles were prepared in aqueous phase by a simple reduction-route using sodium borohydride as the reducing agent in the presence of ascorbic acid and polyvinylpyrrolidone (PVP). The hydrosol of Cu nanoparticles deteriorated within a day. It compelled to initiate a scheme to stabilize the nanoparticles for long period of time. Read More

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http://dx.doi.org/10.1088/1361-6528/ab9574DOI Listing

Development of enteric polymer-based microspheres by spray-drying for colonic delivery of Lactobacillus rhamnosus GG.

Int J Pharm 2020 May 8:119414. Epub 2020 May 8.

Univ Lyon, Université Claude Bernard Lyon 1, LAGEPP UMR 5007 CNRS, 43 boulevard du 11 novembre 1918, F-69100, Villeurbanne, France.

Antibiotics are well-known disruptive elements of the intestinal microbiota and antibiotic-associated diarrhea appeared as the most common complication related with post-antibiotic dysbiosis. Lactobacillus rhamnosus GG (LGG) strain is very effective in preventing antibiotic-associated diarrhea in children and adults. However, as any probiotics, it is concerned by the loss of viability during storage and gastrointestinal transit. Read More

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http://dx.doi.org/10.1016/j.ijpharm.2020.119414DOI Listing

Comparing Computational Predictions and Experimental Results for Aluminum Triflate in Tetrahydrofuran.

J Phys Chem B 2020 May 21. Epub 2020 May 21.

Exploring reliable electrolytes for aluminum ion batteries requires an in-depth understanding of the behavior of aluminum ions in ethereal-organic solvents. Electrolytes comprised of aluminum trifluoromethanesulfonate (Al-triflate) in tetrahydrofuran (THF) were investigated computationally and experimentally. Optimized geometries, redox potentials and vibrational frequencies of species likely to be present in the electrolyte were calculated by DFT and then measured spectroscopically and electrochemically. Read More

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http://dx.doi.org/10.1021/acs.jpcb.0c02570DOI Listing

A Novel Fungal Lipase With Methanol Tolerance and Preference for Macaw Palm Oil.

Front Bioeng Biotechnol 2020 6;8:304. Epub 2020 May 6.

Brazilian Biorenewables National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, Brazil.

Macaw palm is a highly oil-producing plant, which presents high contents of free fatty acids, being a promising feedstock for biofuel production. The current chemical routes are costly and complex, involving highly harsh industrial conditions. Enzymatic processing is a potential alternative; however, it is hampered by the scarce knowledge on biocatalysts adapted to this acidic feedstock. Read More

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http://dx.doi.org/10.3389/fbioe.2020.00304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218172PMC

Toxicity of Organic Solvent in a Young Painter Presenting as Transient Hepatitis: A Case Report.

Indian J Occup Environ Med 2020 Jan-Apr;24(1):33-35. Epub 2020 Mar 18.

Department of Biochemistry, Dr BSA Medical College and Hospital, New Delhi, India.

Organic solvents widely used in paint manufacturing, painting, and shoemaking industries may be associated with hepatotoxicity. We present a case report of a patient with prolonged occupational exposure to organic solvents who developed transient hepatitis. Monitoring contact to these chemicals and early identification of biological markers of occupational exposure should be done. Read More

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http://dx.doi.org/10.4103/ijoem.IJOEM_61_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227743PMC

Impact of nanoconfinement on acetylacetone equilibria in ordered mesoporous silicates.

Nanotechnology 2020 May 20. Epub 2020 May 20.

Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, BRAZIL.

Nanoconfinement is one of the most intriguing nanoscale effects and affects several physical and chemical properties of molecules and materials, including viscosity, reaction kinetics, and glass transition temperature. In this work, liquid nuclear magnetic resonance (NMR) was used to analyze the behavior of 2,4-pentadienone in ordered mesoporous materials with a pore diameter of between 3 and 10 nm. The liquid NMR results showed meaningful changes in the hydrogen chemical shift and the keto-enol chemical equilibrium, which were associated with the pore diameter, allowing the authors to observe the effects of nanoconfinement. Read More

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http://dx.doi.org/10.1088/1361-6528/ab94dbDOI Listing

New Insights into the Stability of Anhydrous 2H-imidazolium Fluoride and its High Dissolution Capability toward a Strongly Hydrogen-bonded Compound.

J Am Chem Soc 2020 May 20. Epub 2020 May 20.

Fluorides have been widely applied in pharmaceutical, medici-nal, and materials science, as well as in fine chemical manufac-turing. The performance of fluorides, however, can be markedly affected by the water content. One previous study suggested that the anhydrous 1,3-dimethylimidazolium fluoride ([DMIm]F) was unstable since the fluoride undergoes a self-decomposition reac-tion. Read More

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http://dx.doi.org/10.1021/jacs.0c04160DOI Listing

Determining Proton-Coupled Standard Potentials and X-H Bond Dissociation Free Energies in Nonaqueous Solvents using Open-Circuit Potential Measurements.

J Am Chem Soc 2020 May 20. Epub 2020 May 20.

Proton-coupled electron transfer (PCET) reactions are increasingly being studied in nonaqueous conditions, where the thermochemistry of PCET substrates is largely unknown. Herein, we report a method to obtain electrochemical standard potentials and the corresponding X-H bond dissociation free energies (BDFEs) of stable PCET reagents in nonaqueous solvents, using open-circuit potential (OCP) measurements. With this method, we measure PCET thermochemistry in acetonitrile and tetrahydrofuran for substrates with O-H and N-H bonds that undergo 1e-/1H+ and 2e-/2H+ redox processes. Read More

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http://dx.doi.org/10.1021/jacs.0c01032DOI Listing

Endowing chloroplasts with artificial "cell walls" using metal-organic frameworks.

Nanoscale 2020 May 20. Epub 2020 May 20.

MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, and College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, P. R. China.

Biological photosynthesis via chloroplasts (CHs) is widely recognized as the most appropriate and effective method to convert solar energy and simultaneously supply nutrition to maintain life on earth. It is of great significance to prepare CH-based biohybrids which not only can artificially simulate the photocatalytic functionality of CH-containing plants and bacteria, but also can be easily prepared, stored for a long period and conveniently utilized when needed. In this work, for the first time, CHs were encapsulated into metal-organic frameworks (MOFs), namely zeolitic imidazolate frameworks (ZIF-8), under very gentle reaction conditions, i. Read More

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http://dx.doi.org/10.1039/d0nr02206cDOI Listing

Optimization of Glycolipid Synthesis in Hydrophilic Deep Eutectic Solvents.

Front Bioeng Biotechnol 2020 5;8:382. Epub 2020 May 5.

Institute of Process Engineering in Life Sciences II: Chair of Technical Biology, Karlsruhe Institute of Technology, Karlsruhe, Germany.

Glycolipids are considered an alternative to petrochemically based surfactants because they are non-toxic, biodegradable, and less harmful to the environment while having comparable surface-active properties. They can be produced chemically or enzymatically in organic solvents or in deep eutectic solvents (DES) from renewable resources. DES are non-flammable, non-volatile, biodegradable, and almost non-toxic. Read More

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http://dx.doi.org/10.3389/fbioe.2020.00382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214929PMC

Ligand and Solvent Selection for Enhanced Separation of Palladium Catalysts by Organic Solvent Nanofiltration.

Front Chem 2020 5;8:375. Epub 2020 May 5.

Department of Chemical Engineering, University of Bath, Bath, United Kingdom.

Organic solvent nanofiltration (OSN) has been widely applied to separate and recycle homogeneous catalysts, but the influence of ligand and solvent selection on the performance of OSN is not fully understood. Here we prepared four palladium (Pd) catalysts by combining palladium acetate with four ligands of different molecular weights. Morphological and functional properties of the Pd catalysts were characterized by TEM, FTIR, and NMR. Read More

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http://dx.doi.org/10.3389/fchem.2020.00375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216237PMC

Sustainable Process for the Depolymerization/Oxidation of Softwood and Hardwood Kraft Lignins Using Hydrogen Peroxide under Ambient Conditions.

Molecules 2020 May 16;25(10). Epub 2020 May 16.

Institute for Chemicals and Fuels from Alternative Resources (ICFAR), Western University, London, ON N6A 5B9, Canada.

The present study demonstrated a sustainable and cost-effective approach to depolymerize/oxidize softwood (SW) and hardwood (HW) kraft lignins using concentrated hydrogen peroxide at temperatures ranging from 25 to 35 °C, in the absence of catalysts or organic solvents. The degree of lignin depolymerization could be simply controlled by reaction time, and no further separation process was needed at the completion of the treatment. The obtained depolymerized lignin products were comprehensively characterized by GPC-UV, FTIR, P-NMR, TGA, Py-GC/MS and elemental analysis. Read More

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http://dx.doi.org/10.3390/molecules25102329DOI Listing

Ruthenacarborane-Phenanthroline Derivatives as Potential Metallodrugs.

Molecules 2020 May 15;25(10). Epub 2020 May 15.

Institute of Inorganic Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Ruthenium-based complexes have received much interest as potential metallodrugs. In this work, four Ru complexes bearing a dicarbollide moiety, a carbonyl ligand, and a phenanthroline-based ligand were synthesized and characterized, including single crystal diffraction analysis of compounds , , and and an observed side product . Complexes - are air and moisture stable under ambient conditions. Read More

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http://dx.doi.org/10.3390/molecules25102322DOI Listing

Amphiphilic Polymeric Nanoparticles for Photoredox Catalysis in Water.

Chemistry 2020 May 19. Epub 2020 May 19.

Institute for complex molecular systems, Chemical engineering and chemistry, NETHERLANDS.

Photoredox catalysis has recently emerged as a powerful synthesis tool in organic and polymer chemistry. In contrast to the great achievements realized in organic solvents, performing photocatalytic processes efficiently in aqueous media encounters several challenges. Here, we present how amphiphilic single-chain polymeric nanoparticles (SCPNs) can be utilized as small reactors to conduct light-driven chemical reactions in water. Read More

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http://dx.doi.org/10.1002/chem.202001767DOI Listing

Hydrogen-Bond Catalysis of Imine Exchange in Dynamic Covalent Systems.

Chemistry 2020 May 19. Epub 2020 May 19.

Royal Institute of Technology, Department of Chemistry, Teknikringen 30, 10044, Stockholm, SWEDEN.

The reversibility of imine bonds has been exploited to great effect in the field of dynamic covalent chemistry, with applications such as preparation of functional systems, dynamic materials, molecular machines, and covalent organic frameworks. However, acid catalysis is commonly needed for efficient equilibration of imine mixtures. Herein, it is demonstrated that hydrogen bond donors such as thioureas and squaramides can catalyze the equilibration of dynamic imine systems under unprecedentedly mild conditions. Read More

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http://dx.doi.org/10.1002/chem.202001666DOI Listing

Expanded benzofuran-decorated twistacene derivatives: synthesis, characterization and single-component white electroluminescence.

Phys Chem Chem Phys 2020 May 19. Epub 2020 May 19.

College of Chemistry and Environmental Science, Key Laboratory of Chemical Biology of Hebei Province, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Hebei University, Baoding 071002, P. R. China.

Two novel phenanthro[9,10-b]benzofuran and pyreno[4,5-b]benzofuran modified twistacene derivatives, 9 and 10, have been successfully synthesized via Suzuki coupling and then characterized. The photophysical properties were examined and DFT calculations were carried out in a comparative manner, and both molecules emitted strong blue light in organic solvents and in the solid state. Impressively, fabricated electroluminescent devices based on these single emitters radiate pure white light. Read More

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http://dx.doi.org/10.1039/d0cp01796eDOI Listing

Immobilized microbial lipases in the food industry: a systematic literature review.

Crit Rev Food Sci Nutr 2020 May 19:1-15. Epub 2020 May 19.

Specialization course in Biotechnology and Bioprocesses, Graduate Program in Environmental Biotechnology, Universidade Estadual de Maringá, Maringá, PR, Brazil.

Several studies describe the immobilization of microbial lipases aiming to evaluate the mechanical/thermal stability of the support/enzyme system, the appropriate method for immobilization, acid and alkaline stability, tolerance to organic solvents and specificity of fatty acids. However, literature reviews focus on application of enzyme/support system in food technology remains scarce. This current systematic literature review aimed to identify, evaluate and interpret available and relevant researches addressing the type of support and immobilization techniques employed over lipases, in order to obtain products for food industry. Read More

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http://dx.doi.org/10.1080/10408398.2020.1764489DOI Listing

Mantonico and Pecorello Grape Seed Extracts: Chemical Characterization and Evaluation of Wound-Healing and Anti-Inflammatory Activities.

Pharmaceuticals (Basel) 2020 May 14;13(5). Epub 2020 May 14.

Department of Pharmacy, Health and Nutritional Sciences, Department of Excellence 2018-2022, University of Calabria, Edificio Polifunzionale, 87036 Rende (CS), Italy.

The winemaking process produces a huge number of pomaces that generally are used for energy purposes. Further valuable applications such as health-promoting properties are still under investigation. The seeds of the white berries of Mantonico and Pecorello were extracted in a Soxhlet apparatus, using -hexane and chloroform as solvents. Read More

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http://dx.doi.org/10.3390/ph13050097DOI Listing

Morphological transformation in supramolecular assembly of discotic liquid crystal molecules by silver nanoparticles and its sensing application.

Nanotechnology 2020 May 18. Epub 2020 May 18.

Raman Research Institute, Bangalore 560080, India, Bangalore, INDIA.

The triphenylene based discotic liquid crystal (TP) molecules are rich in $\pi$-electrons which facilitate $\pi$-stacking interaction of the molcules leading to formation of one dimensional nanowires. These nanowires can assemble to form nanoribbons due to a lateral cohesive force among the nanowires. The flat nanoribons undergo a morphological transformation due to incorporation of silver nanoparticles (SNP) into the matrix of TP molecules. Read More

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http://dx.doi.org/10.1088/1361-6528/ab93ebDOI Listing
May 2020
3.821 Impact Factor

Continuous Flow Bioamination of Ketones in Organic Solvents at Controlled Water Activity using Immobilized ω-Transaminases.

Adv Synth Catal 2020 Apr 17;362(9):1858-1867. Epub 2020 Feb 17.

Van't Hoff Institute for Molecular Sciences, HIMS-Biocat University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands.

Compared with biocatalysis in aqueous media, the use of enzymes in neat organic solvents enables increased solubility of hydrophobic substrates and can lead to more favorable thermodynamic equilibria, avoidance of possible hydrolytic side reactions and easier product recovery. ω-Transaminases from . (AsR-ωTA) and (Cv-ωTA) were immobilized on controlled porosity glass metal-ion affinity beads (EziG) and applied in neat organic solvents for the amination of 1-phenoxypropan-2-one with 2-propylamine. Read More

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http://dx.doi.org/10.1002/adsc.201901274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217232PMC

Advanced Functional Hierarchical Nanoporous Structures with Tunable Microporous Coatings Formed via an Interfacial Reaction Processing.

ACS Appl Mater Interfaces 2020 May 17. Epub 2020 May 17.

It is challenging, but in an urgent need, to construct hierarchical nanoporous structures with microporous coatings for various important applications, such as entrapment of homogeneous catalysts, size/shape selective catalysis, etc. Moreover, microporous inorganic coatings are particularly desirable because of their excellent stability in organic solvents and at elevated temperature and pressure. In this study, we design a novel liquid phase interfacial reaction (LPIR) process to form a defect-free, hybrid coating, which can be subsequently converted into microporous coatings with tunable pore size, on nanoporous materials. Read More

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http://dx.doi.org/10.1021/acsami.0c05310DOI Listing

An Extensive Study of Coumarin Synthesis via Knoevenagel Condensation in Choline Chloride Based Deep Eutectic Solvents.

Curr Org Synth 2020 ;17(2):98-108

Faculty of Food Technology Osijek, Josip Juraj Strossmayer University o, Franje Kuhaca 18, 31000 Osijek, Croatia.

Aim And Objective: In order to preserve the environment from harmful organic solvents, a synthesis of coumarin derivatives was performed in deep eutectic solvents, which are considered as "green" due to their characteristics.

Materials And Methods: Choline chloride based deep eutectic solvents (DESs) were employed, both as solvents and as catalysts, in the synthesis of coumarin derivatives via Knoevenagel condensation. In order to find the best DES for coumarin synthesis, 20 DESs were tested for the reaction of salicylaldehyde and dimethyl malonate at 80 °C. Read More

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http://dx.doi.org/10.2174/1570179417666200116155704DOI Listing
January 2020

Grafted nanocellulose and alkaline nanoparticles for the strengthening and deacidification of cellulosic artworks.

J Colloid Interface Sci 2020 May 6;576:147-157. Epub 2020 May 6.

CSGI and Chemistry Department, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, FI, Italy. Electronic address:

Hypothesis: Strongly degraded cellulosic artworks usually need deacidification and consolidation. Alkaline nanoparticles are known to be effective in neutralizing the acidity, while cellulose nanocrystals have the potential to be used as compatible and effective strengthening agents.

Experiments: We have grafted cellulose nanocrystals with oleic acid using a 1'1-carbonyldiimidazole-mediated procedure, to increase their dispersibility in organic solvents, and synthesized Ca(OH) or CaCO nanoparticles via a solvothermal process. Read More

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http://dx.doi.org/10.1016/j.jcis.2020.05.018DOI Listing

An environmentally friendly sodium dodecyl sulphate-synergistic microwave-assisted extraction followed by ultra-high performance liquid chromatography with photodiode array method for the simultaneous extraction and determination of iridoids, phenylpropanoids, and lignans from Eucommiae Cortex.

J Sep Sci 2020 May 16. Epub 2020 May 16.

Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.

A simple and green sodium dodecyl sulphate-synergistic microwave-assisted extraction method was developed to extract and determine the iridoids, phenylpropanoids, and lignans in Eucommiae Cortex followed by ultra-high-performance liquid chromatography with photodiode array detection. The biodegradable solution (sodium dodecyl sulphate) was used as a promising alternative to organic solvents. The response surface methodology provided the optimum extraction conditions (2 mg/mL sodium dodecyl sulphate, 1100 W microwave power, and 6 min extraction time). Read More

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http://dx.doi.org/10.1002/jssc.201901279DOI Listing

Change of Quadrupole Moment upon Excitation and  Symmetry Breaking in Multibranched Donor-Acceptor Dyes.

Chemphyschem 2020 May 15. Epub 2020 May 15.

Universite de Geneve, Sciences II, Dept. de chimie physique, 30, Quai Ernest Ansermet, 1211, Geneve 4, SWITZERLAND.

Upon photoexcitation, a majority of quadrupolar dyes, developed for large two-photon absorption, undergo excited-state symmetry breaking (ES-SB) and behave as dipolar molecules. We investigate how the change of quadrupole moment upon S 1  <- S 0  excitation, Δ Q , influences the propensity of a dye to undergo ES-SB using a series of molecules with a A -π- D -π- A motif where D is the exceptionally electron-rich pyrrolo[3,2-b]pyrrole and A are accepting groups. Tuning of Δ Q is achieved by appending a secondary acceptor group, A' , on both sides of the D core and ES-SB is monitored using a combination of time-resolved IR and broadband fluorescence spectroscopy. Read More

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http://dx.doi.org/10.1002/cphc.202000253DOI Listing

Keratinolytic enzyme-mediated biodegradation of recalcitrant poultry feathers waste by newly isolated Bacillus sp. NKSP-7 under submerged fermentation.

Folia Microbiol (Praha) 2020 May 16. Epub 2020 May 16.

Institute of Industrial Biotechnology, GC University, Lahore, 54000, Pakistan.

Microbial and enzymatic degradation of keratin waste is more preferred over various conventional approaches which are costly and not environmentally suitable. Diverse niches are auspicious for the discovery of new microorganisms. To discover novel keratinolytic bacteria, 60 isolates from different poultry dumping sites were initially screened, and among these found a potent keratinolytic isolate (NKSP-7) that displayed higher feather-degrading ability. Read More

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http://dx.doi.org/10.1007/s12223-020-00793-6DOI Listing

Sulfur dioxide removal: An overview of regenerative flue gas desulfurization and factors affecting desulfurization capacity and sorbent regeneration.

Environ Sci Pollut Res Int 2020 May 16. Epub 2020 May 16.

Department of Chemical Engineering, Faculty of Chemical and Energy Engineering, Universiti Teknologi Malaysia (UTM), 81310, Johor Bahru, Johor, Malaysia.

Numerous mitigation techniques have been incorporated to capture or remove SO with flue gas desulfurization (FGD) being the most common method. Regenerative FGD method is advantageous over other methods due to high desulfurization efficiency, sorbent regenerability, and reduction in waste handling. The capital costs of regenerative methods are higher than those of commonly used once-through methods simply due to the inclusion of sorbent regeneration while operational and management costs depend on the operating hours and fuel composition. Read More

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http://dx.doi.org/10.1007/s11356-020-09191-4DOI Listing

Analysis of Four Solvatomorphs of Betulin by TG-DTA-EI/PI-MS System Equipped with the Skimmer-Type Interface.

Nat Prod Bioprospect 2020 May 15. Epub 2020 May 15.

Beijing City Key Laboratory of Drug Target and Screening Research, National Center for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, People's Republic of China.

Betulin (BE) has exceedingly become a potential natural product, providing multiple pharmacological and biological activities, including anti-cancer, anti-viral, and anti-inflammatory benefits. Previous research indicated that the solvatomorphism of BE can easily occur through crystallization with different organic solvents. This property of BE can directly affect its extraction, isolation, and preparation process. Read More

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http://dx.doi.org/10.1007/s13659-020-00243-3DOI Listing

Effective oxidative degradation of coal gasification wastewater by ozonation: A process study.

Chemosphere 2020 May 3;255:126963. Epub 2020 May 3.

School of Materials and Energy, University of Electronic Science and Technology of China, Chengdu, 611731, China; Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, 830011, China.

Coal gasification wastewater (CGW) has attracted considerable industrial attention because of its high toxicity and poor biodegradability. Ozonation is a promising process for CGW treatment. In this study, the effects of ozone concentration, pH, and ozonation time on CGW treatment were investigated. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2020.126963DOI Listing

Direct carbonization of organic solvents toward graphene quantum dots.

Nanoscale 2020 May 15. Epub 2020 May 15.

High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei 230031, Anhui, P. R. China. and The Anhui Key Laboratory of Condensed Matter Physics at Extreme Conditions, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, Anhui, P. R. China and Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, Anhui, China.

The bottom-up synthesis of graphene quantum dots (GQDs) using solvothermal methods has attracted considerable attention because of their fewer defects and controllable size/morphology. However, the influence of organic solvents on the preparation of GQDs is still unknown. Herein, a systematic study on the carbonization of organic solvents toward GQDs is reported. Read More

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http://dx.doi.org/10.1039/d0nr01903hDOI Listing

An Overview of Properties and Analytical Methods for Lycopene in Organic Nanocarriers.

Crit Rev Anal Chem 2020 May 15:1-13. Epub 2020 May 15.

School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.

Lycopene (LYC), a natural compound responsible for the red color of some fruits like pink grapefruit, red guava, watermelon, papaya and, mainly, present in tomatoes (). LYC has been extensively studied because of its various pharmacological properties such as antioxidant, cardioprotective, hypocholesterolemic, antineophasic, photoprotection, antidiabetic and antimicrobial activity. However, LYC uses in therapy is limited due to its insolubility in aqueous solvents, resulting in low bioavailability and stability. Read More

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http://dx.doi.org/10.1080/10408347.2020.1763774DOI Listing

UV Light Generation and Challenging Photoreactions Enabled by Upconversion in Water.

J Am Chem Soc 2020 May 15. Epub 2020 May 15.

Sensitized triplet-triplet annihilation (sTTA) is the most promising mechanism for pooling the energy of two visible photons, but its applications in solution were so far limited to organic solvents, with a current maximum of the excited-singlet state energy of 3.6 eV. By combining tailor-made iridium complexes with naphthalenes, we demonstrate blue-light driven upconversion in water with unprecedented singlet-state energies approaching 4 eV. Read More

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http://dx.doi.org/10.1021/jacs.0c02835DOI Listing

Enhanced Water Dispersibility of Discrete Chalcogenide Nanoclusters with a Sodalite-Net Loose-Packing Pattern in a Crystal Lattice.

Inorg Chem 2020 May 15. Epub 2020 May 15.

College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, Jiangsu 215123, China.

Good aqueous dispersibility of metal chalcogenide nanoclusters with an atomically precise structure is desirable to achieve tiny and uniform cluster-based "quantum dots". However, there are big challenges toward this goal, especially for the large-sized nanoclusters without covalently bonded organic ligands, because the strong electrostatic interactions between closely packed negatively charged nanoclusters and protonated organic amine templates in the crystal lattice impede the dispersion of cluster-based bulk crystalline samples. Here, we report two iso-structured crystalline metal chalcogenides composed of discrete supertetrahedral T4-MInS nanoclusters with the formulas of [MInS] (denoted M, M = Zn and Fe), which adopt a sodalite-net loose-packing pattern in the crystal lattice and display superior dispersibility in water and some organic solvents as compared to other cases composed of the same type of nanoclusters with close-packing pattern. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.0c00621DOI Listing

Functionalizable oxanorbornane-based head-group in the design of new Non-ionic amphiphiles and their drug delivery properties.

Mater Sci Eng C Mater Biol Appl 2020 Jul 18;112:110857. Epub 2020 Mar 18.

Department of Chemistry, Indian Institute of Technology Madras, Chennai 600 036, India. Electronic address:

A new group of non-ionic amphiphiles with short alkyl chains and functionalizable oxanorbornane-based head group for drug delivery application are presented. They can be prepared through a sequence that starts with cycloaddition of Boc-protected furfuryl amine with maleic anhydride and reduction of the resulting adduct with LiAlH to get a diol intermediate. Introduction of alkyl chains through these primary hydroxyl groups and subsequent head-group modification via cis-hydroxylation resulted in a number of new amphiphiles in good yields. Read More

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http://dx.doi.org/10.1016/j.msec.2020.110857DOI Listing

Potential Application of Ionic Liquids in Pharmaceutical Dosage Forms for Small Molecule Drug and Vaccine Delivery System.

J Pharm Pharm Sci 2020 ;23:158-176

College of Pharmacy, Larkin University, Miami, FL 33169, USA.

Ionic liquids are salts in which the ions are poorly coordinated, which causes them to exist in liquid form below 100°C, or at room temperature. Therefore, these are also defined as room temperature ionic liquids (RTILs). In ionic liquids, at least one ion has a delocalized charge and one component is organic, which prevents the formation of a stable solid form of crystal lattice. Read More

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http://dx.doi.org/10.18433/jpps30965DOI Listing
January 2020

A new antimicrobial compound from the leaves of for infectious diseases.

Bioact Mater 2020 Sep 6;5(3):602-610. Epub 2020 May 6.

School of Pharmacy, College of Pharmacy and Nursing, University of Nizwa, P.O. Box 33, 616, Nizwa, Oman.

The main aim of this research work was to isolate and characterize the antimicrobial compounds that can be extracted from the leaves of () and to assess their antimicrobial potency by established agar diffusion method. The methanol extract was liquefied and fractioned by using a separatory funnel and organic solvents having different polarities. The agar diffusion technique was used to assess the antimicrobial potency of extracts and pure compounds against 5 g (+and -) microbial strains. Read More

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http://dx.doi.org/10.1016/j.bioactmat.2020.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210477PMC
September 2020

Partial purification and characterization of a broad-spectrum bacteriocin produced by a zrx03 isolated from infant's feces.

Food Sci Nutr 2020 May 18;8(5):2214-2222. Epub 2020 Mar 18.

Wageningen University and Research Centre Wageningen The Netherlands.

zrx03 was a bacteriocin-producing strain isolated from infant's feces. The fermentation supernatant produced by this strain could strongly inhibit JM109 ATCC 67387, ATCC 25923, and CICC 21633, in which the diameter of inhibition zone was 12.83 ± 0. Read More

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http://dx.doi.org/10.1002/fsn3.1428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215221PMC

Isolation and characterization of a novel O157:H7-specific phage as a biocontrol agent.

J Environ Health Sci Eng 2020 Jun 6;18(1):189-199. Epub 2020 Feb 6.

3School of Food Science and Biotechnology, Kyungpook National University, Daegu, Republic of Korea.

Purpose: O157:H7 is one of the major foodborne pathogens of global public concern. Bacteriophages (phages) have emerged as a promising alternative to antibiotics for controlling pathogenic bacteria. Here, a lytic O157:H7-specific phage (KFS-EC) was isolated, identified, and characterized to evaluate its potential as a biocontrol agent for O157:H7. Read More

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http://dx.doi.org/10.1007/s40201-020-00452-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203308PMC

NONIONIC SURFACTANTS FOR THE CLEANING OF WORKS OF ART: INSIGHTS ON ACRYLIC POLYMER FILMS DEWETTING AND ARTIFICIAL SOIL REMOVAL.

ACS Appl Mater Interfaces 2020 May 12. Epub 2020 May 12.

The use of nanostructured fluids (NSFs, i.e. micellar solutions and microemulsions) in art conservation is often associated to cleaning purposes, as the removal of polymeric coatings and/or soil from artistic surfaces. Read More

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http://dx.doi.org/10.1021/acsami.0c06425DOI Listing

Systemic sclerosis in an anaesthetist.

Occup Med (Lond) 2020 May 12. Epub 2020 May 12.

Post-Graduate School of Occupational Health, Università Cattolica del Sacro Cuore, Rome, Italy.

Introduction: Systemic sclerosis is a potentially devastating disease in which the aetiology and pathogenesis has not yet been fully understood. It has been associated with occupational exposure to silica, vinyl chloride, solvents and other chemical agents.

Case Summary: In this paper, we present the case of an anaesthetist who developed scleroderma after an occupational exposure to volatile anaesthetic gases (halothane, sevoflurane, isoflurane and enflurane) in operating theatres with poor scavenging systems and we discuss the possible causal link between occupational exposure and the disease. Read More

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http://dx.doi.org/10.1093/occmed/kqaa068DOI Listing

Understanding Molecular Interactions in Rafoxanide-Povidone Amorphous Solid Dispersions from Ultrafast Magic Angle Spinning NMR.

Mol Pharm 2020 May 21. Epub 2020 May 21.

Pharmaceutical Sciences, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.

In solid dosage formulations, probing intermolecular interactions between active pharmaceutical ingredients (APIs) and polymeric excipients, which have a mechanistic impact on physical stability as well as bioavailability, remains a challenge. In recent years, solid-state NMR spectroscopy has been demonstrated to be a powerful tool to provide structural details with an atomic resolution of therapeutic organic compounds and formulation products. However, conventional C-detected techniques often suffer from poor resolution and low sensitivity due to the disordered structure of certain materials such as amorphous pharmaceuticals and C natural abundance, hindering in-depth investigations. Read More

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http://dx.doi.org/10.1021/acs.molpharmaceut.0c00317DOI Listing

Global and Kinetic Profiles of Substrate Diffusion in Lipase B: Molecular Dynamics with the Markov-State Model.

ACS Omega 2020 May 23;5(17):9806-9812. Epub 2020 Apr 23.

Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.

Profiling substrate diffusion pathways with kinetic information, which accounts for the dynamic nature of enzyme-substrate interaction, can enable molecular reengineering of enzymes and process optimization of enzymatic catalysis. lipase B (CALB) is extensively used for producing various chemicals because of its rich catalytic mechanisms, broad substrate spectrum, thermal stability, and tolerance to organic solvents. In this study, an all-atom molecular dynamics (MD) combined with Markov-state models (MSMs) implemented in pyEMMA was proposed to simulate diffusion pathways of 4-nitrophenyl ester (4NPE), a commonly used substrate, from the surface into the active site of CALB. Read More

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http://dx.doi.org/10.1021/acsomega.9b04432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203684PMC