34,603 results match your criteria Organic Solvents

Solvent Engineering as a Vehicle for High Quality Thin Films of Perovskites and Their Device Fabrication.

Small 2021 May 14:e2008145. Epub 2021 May 14.

Department of Electrical and Electronic Engineering, Advanced Technology Institute (ATI), University of Surrey, Guildford, Surrey, GU2 7XH, UK.

Organic-inorganic halide perovskite solar cells (PSCs) have shown a significant growth in power conversion efficiencies (PCEs) during last decade. Progress in device architecture and high-quality perovskite film fabrication has led to an incredible efficiency over 25% in close to a decade. Developments in solution-based thin film deposition techniques for perovskite layer preparation in PSCs provide low cost and ease of process for their manufacturing, making them a potential contender in future solar energy harvesting technologies. Read More

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Impaired neuromuscular function by conjoint actions of organophosphorus insecticide metabolites omethoate and cyclohexanol with implications for treatment of respiratory failure.

Clin Toxicol (Phila) 2021 May 14:1-20. Epub 2021 May 14.

Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.

Background: Ingestion of agricultural organophosphorus insecticides is a significant cause of death in rural Asia. Patients often show acute respiratory failure and/or delayed, unexplained signs of neuromuscular paralysis, sometimes diagnosed as "Intermediate Syndrome". We tested the hypothesis that omethoate and cyclohexanol, circulating metabolites of one agricultural formulation, cause muscle weakness and paralysis. Read More

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Significant contribution of spring northwest transport to volatile organic compounds in Beijing.

J Environ Sci (China) 2021 Jun 18;104:169-181. Epub 2020 Dec 18.

Center for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China; State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

High values of ozone (O) occur frequently in the dry spring season; thus, understanding the evolution characteristics of volatile organic compounds (VOCs) in spring is of great significance for preventing O pollution. In this study, a total of 101 VOCs from April 16 to May 21, 2019, were quantified using an online gas chromatography mass spectrometer/flame ionization detector (GCMS/FID). The results indicated that the observed concentration of total VOCs (TVOCs) was 30. Read More

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Quenching Mechanism of Uranyl(VI) by Chloride and Bromide in Aqueous and Non-Aqueous Solutions.

J Phys Chem A 2021 May 13. Epub 2021 May 13.

Institute of Chemistry, University of Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.

A major hindrance in utilizing uranyl(VI) luminescence as a standard analytical tool, for example, in environmental monitoring or nuclear industries, is quenching by other ions such as halide ions, which are present in many relevant matrices of uranyl(VI) speciation. Here, we demonstrate through a combination of time-resolved laser-induced fluorescence spectroscopy, transient absorption spectroscopy, and quantum chemistry that coordinating solvent molecules play a crucial role in U(VI) halide luminescence quenching. We show that our previously suggested quenching mechanism based on an internal redox reaction of the 1:2-uranyl-halide-complex holds also true for bromide-induced quenching of uranyl(VI). Read More

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Optimization of PhysicoChemical Parameters for Production of Cytotoxic Secondary Metabolites and Apoptosis Induction Activities in the Culture Extract of a Marine Algal-Derived Endophytic Fungus sp.

Front Pharmacol 2021 26;12:542891. Epub 2021 Apr 26.

Department of Biochemistry, Indian Institute of Science, Bangalore, India.

The endophytic fungal community in the marine ecosystem has been demonstrated to be relevant source of novel and pharmacologically active secondary metabolites. The current study focused on the evaluation of cytotoxic and apoptosis induction potential in the culture extracts of endophytic fungi associated with , a marine brown alga. The cytotoxicity of the four marine endophytes, sp. Read More

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A Facile Synthesis of Nido-Carborane Polymers via Dynamic Self-Assembly by Poly(carboxybetaine methacrylate).

Zhou Wang

J Nanosci Nanotechnol 2021 Nov;21(11):5681-5687

College of Vanadium and Titanium, Panzhihua University, 617000, P. R. China.

Carborane are widely applied in boron neutron capture therapy (BNCT) field, but it is difficult to perform biocompatibility with cells due to its own water solubility differences, so how to solve the water solubility problem has always been the focus of research. A simple, inexpensive and effective method was used to study the synthesis of nido-carborane azaspirodecanium poly(carboxybetaine methacrylate) by one-pot cyclization of nido-carborane azaspirodecanium under the synergistic effect of inorganic bases and conventional organic solvents. Its characterization is mainly to use 1H-NMR nuclear magnetic resonance spectrum and infrared spectroscopy to determine the characteristic peak and range of borane. Read More

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November 2021

A new method to prepare microparticles based on an Aqueous Two-Phase system (ATPS), without organic solvents.

J Colloid Interface Sci 2021 Mar 27;599:642-649. Epub 2021 Mar 27.

Micro et Nanomédecines translationnelles, MINT, UNIV Angers, UMR INSERM 1066, UMR CNRS 6021, Angers, France. Electronic address:

Hypothesis: Aqueous Two-Phase Systems (ATPS) are aqueous droplets dispersed in an aqueous phase. This specific behavior arises from interactions between at least two water-soluble entities, such as thermodynamically incompatible polymers. A simple, fast, and "green" process to produce ATPS with an aqueous core would be of high interest to the pharmaceutical field for drug delivery. Read More

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Solvatomorphism Influence of Porous Organic Cage on CH/CO Separation.

ACS Appl Mater Interfaces 2021 May 12. Epub 2021 May 12.

State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, China.

Porous organic molecular (POM) materials can exhibit solvatomorphs via altering their crystallographic packing in the solid state, but investigating real gas mixture separation by porous materials with such a behavior is still very rare. Herein, we report that a lantern-shaped calix[4]resorcinarene-based porous organic cage (POC, namely, ) can exhibit eight distinct solid-state solvatomorphs via crystallization in different solvents. This POC solvatomorphism has a significant influence on their gas sorption capacities as well as separation abilities. Read More

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A case of lipoid pneumonia associated with occupational exposure to solvents in a dry-cleaning worker.

Respirol Case Rep 2021 Jun 7;9(6):e00762. Epub 2021 May 7.

Department of Internal Medicine Kyungpook National University, School of Medicine Daegu Republic of Korea.

Lipoid pneumonia can develop from exposure to different types of oil, but occupational exposure is rare. A 58-year-old woman was referred to our hospital for patchy airspace opacities in the lungs with lower lobe predominance on chest computed tomography. She was diagnosed with non-Hodgkin's lymphoma seven years ago, but was in complete remission. Read More

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Review of the toxic effects of ionic liquids.

Sci Total Environ 2021 Apr 30;786:147309. Epub 2021 Apr 30.

School of Chemical Engineering, Chonbuk National University, 567 Beakje-dearo, Deokjin-gu, Jeonju, Jeonbuk 561-756, South Korea. Electronic address:

Interest in ionic liquids (ILs), called green or designer solvents, has been increasing because of their excellent properties such as thermal stability and low vapor pressure; thus, they can replace harmful organic chemicals and help several industrial fields e.g., energy-storage materials production and biomaterial pretreatment. Read More

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Highly Soluble Supertetrahedra upon Selective Partial Butylation of Chalcogenido Metalate Clusters in Ionic Liquids.

Angew Chem Int Ed Engl 2021 May 11. Epub 2021 May 11.

Philipps-Universitat Marburg Fachbereich Chemie, Chemie, GERMANY.

Supertetrahedral clusters have been reported in two generally different types so far: one type possessing an organic ligand shell, no or low charges, and high solubility, while the other cluster type is ligand-free with usually high charges and low or no solubility in common solvents. The latter is a tremendous disadvantage regarding further use of the clusters in solution. However, as organic substituents usually broaden the HOMO-LUMO gaps, which cannot be overcompensated by the (limited) cluster sizes, a full organic shielding comes along with drawbacks regarding opto-electronic properties. Read More

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A new amido-phosphane as ligand for copper and silver complexes. Synthesis, characterization and catalytic application for azide-alkyne cycloaddition in glycerol.

Dalton Trans 2021 May;50(18):6109-6125

Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal. and Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, Moscow 117198, Russian Federation.

The new sterically hindered amido-phosphane 1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane-3,7-diylbis(phenylmethanone), DBPTA (1), has been obtained via an open-cage double N-acylation of 1,3,5-triaza-7-phosphadamantane (PTA) using benzoic anhydride. Read More

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Surpassing 13% Efficiency for Polythiophene Organic Solar Cells Processed from Nonhalogenated Solvent.

Adv Mater 2021 May 10:e2008158. Epub 2021 May 10.

State Key Laboratory of Luminescent Materials and Devices, Institute of Polymer Optoelectronic Materials and Devices, School of Materials Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou, 510640, P. R. China.

Benefiting from low cost and simple synthesis, polythiophene (PT) derivatives are one of the most popular donor materials for organic solar cells (OSCs). However, polythiophene-based OSCs still suffer from inferior power conversion efficiency (PCE) than those based on donor-acceptor (D-A)-type conjugated polymers. Herein, a fluorinated polythiophene derivative, namely P4T2F-HD, is introduced to modulate the miscibility and morphology of the bulk heterojunction (BHJ)-active layer, leading to a significant improvement of the OSC performance. Read More

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Engineering Synthetic Lipopeptide Antigen for Specific Detection of subsp. Infection.

Front Vet Sci 2021 23;8:637841. Epub 2021 Apr 23.

INRAE, Université de Tours, ISP, Nouzilly, France.

Unlike other MAC members, subsp. (MAP) does not produce glycopeptidolipids (GPL) on the surface of the cell wall but a lipopentapeptide called L5P (also termed Lipopeptide-I or Para-LP-01) characterized in C-type (bovine) strains. This lipopeptide antigen contains a pentapeptide core, D-Phenylalanine-N-methyl-L-Valine-L-Isoleucine-L-Phenylalanine-L-Alanine, in which the N-terminal D-Phenylalanine is amido-linked with a fatty acid (C18-C20). Read More

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Structure-property relationships on recrystallized β-cyclodextrin solvates: A focus on X-ray diffractometry, FTIR and thermal analyses.

Carbohydr Polym 2021 Aug 18;265:118079. Epub 2021 Apr 18.

Department of Dental Medicine, "Victor Babeş" University of Medicine and Pharmacy Timişoara, Eftimie Murgu Sq. 2, 300041, Timişoara, Romania. Electronic address:

The goal of the study was to evaluate the influence of the solvent properties on the crystal characteristics of β-cyclodextrin (β-CD) recrystallized from alcohol-water solvent mixtures, with possible applications for the preparation, purifying and complexation of β-CD. For the first time, structure-property relationships (QSPRs) between the hydrophobicity of alcohols or dielectric constant of solvents used for recrystallization of β-CD and its properties (such as crystallinity index, CI) have been obtained. Recrystallized β-CD from water and C-C alcohol-water solutions provide β-CD with higher CI values of 99. Read More

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Enzymatic Cascade Reactions Mediated by Highly Efficient Biomimetic Quasi Metal-Organic Frameworks.

ACS Appl Mater Interfaces 2021 May 9. Epub 2021 May 9.

Guangdong Provincial Key Lab of Green Chemical Product Technology, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.

The integration of chemo- and enzymatic catalysis for effective multistep cascades has presented critical challenges for decades. In this work, the biomimetic quasi NH-MIL-101 (qNM) with highly efficient peroxidase-like activity was synthesized via a palmitic acid-induced strategy followed by pyrolysis. The effects of the amount of palmitic acid and calcination temperature on the synthesis of qNM were optimized. Read More

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Directed evolution of unspecific peroxygenase in organic solvents.

Biotechnol Bioeng 2021 May 8. Epub 2021 May 8.

Department of Biocatalysis, Institute of Catalysis, CSIC, Madrid, Spain.

Fungal unspecific peroxygenases (UPOs) are efficient biocatalysts that insert oxygen atoms into nonactivated C-H bonds with high selectivity. Many oxyfunctionalization reactions catalyzed by UPOs are favored in organic solvents, a milieu in which their enzymatic activity is drastically reduced. Using as departure point the UPO secretion mutant from Agrocybe aegerita (PaDa-I variant), in the current study we have improved its activity in organic solvents by directed evolution. Read More

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Optimization, and and evaluation of etomidate intravenous lipid emulsion.

Drug Deliv 2021 Dec;28(1):873-883

School of Pharmacy, North China University of Science and Technology, Tangshan, China.

The aim of this investigation was to develop an etomidate intravenous lipid emulsion (ETM-ILE) and evaluate its properties and . Etomidate (ETM) is a hydrophobic drug, and organic solvents must be added to an etomidate injectable solution (ETM-SOL) to aid dissolution, that causes various adverse reactions on injection. Lipid emulsions are a novel drug formulation that can improve drug loading and reduce adverse reactions. Read More

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December 2021

Injectable hydroxypropyl chitin hydrogels embedded with carboxymethyl chitin microspheres prepared via a solvent-free process for drug delivery.

J Biomater Sci Polym Ed 2021 May 6:1-15. Epub 2021 May 6.

Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan, P.R. China.

Microspheres and injectable hydrogels derived from natural biopolymers have been extensively investigated as controlled local drug delivery systems. In this study, we prepared carboxymethyl chitin microspheres (CMCH-Ms) with a diameter of 10-100 μm through physical crosslinking by increasing temperature in an aqueous two-phase system without using organic solvents, surfactants and crosslinking agents. The stable microspheres keeping spherical shape with porous microstructure in different pH environments were embeded in thermosensitive hydroxypropyl chitin (HPCH) hydrogels. Read More

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Divergent functionalization of α,β-enones: catalyst-free access to β-azido ketones and β-amino α-diazo ketones.

Chem Commun (Camb) 2021 May;57(37):4524-4527

College of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, 2055 N. Yan'an Avenue, Changchun 130012, P. R. China.

A simple and practical method for the azidation of β-fluoroalkyl α,β-unsaturated ketones to access a wide variety of fluorinated nitrogenous carbonyl compounds is developed. Different from existing precedents, neither a metallic nor an organic catalyst was involved in our strategy. Judicious choice of solvents allows for the modulation of the reaction outcomes, delivering β-azido ketones or β-amino α-diazo ketones. Read More

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Non-aqueous electrophoresis integrated with electrospray ionization mass spectrometry on a thiol-ene polymer-based microchip device.

Anal Bioanal Chem 2021 May 6. Epub 2021 May 6.

Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.

Non-aqueous capillary electrophoresis (NACE) on microfluidic chips is still a comparatively little explored area, despite the inherent advantages of this technique and its application potential for, in particular, lipophilic compounds. A main reason is probably the fact that implementation of NACE on microchips largely precluded the use of polymeric substrate materials. Here, we report non-aqueous electrophoresis on a thiol-ene-based microfluidic chip coupled to mass spectrometry via an on-chip ESI interface. Read More

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The dynamic interplay between intramolecular and intermolecular interactions in mononuclear manganese(III) SCO complexes.

Dalton Trans 2021 May;50(17):5899-5910

State Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, Nanjing 210023, China.

The effect of counter anions on thermally induced manganese(iii)-based SCO within the [Mn(5-F-sal-N-1,5,8,12)]Y family has been investigated. All the complexes are crystallized without any lattice solvents. Crystal packing and intermolecular forces influence the spin-state stabilization and spin-transition profiles. Read More

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Shorter and Rugged Analytical GC Method for Residual Solvents Content in Active Pharmaceutical Ingredient.

J Chromatogr Sci 2021 May 5. Epub 2021 May 5.

Department of Physical and Nuclear Chemistry and Chemical Oceanography, Andhra University, Waltair Junction, Visakhapatnam 530 003, India.

This work describes the highly selective and sensitive robust analytical method (gas chromatography) for the qualitative and quantitative analysis of commonly used residual solvents (like methanol, ethanol, acetonitrile, dichloromethane, methyl tert-butyl ether, n-hexane, 1-propanol, ethyl acetate, tetrahydrofuran, N,N-diisopropylethylamine (DIPEA) and dimethylformamide), in an active pharmaceuticals ingredients. The developed method was optimized with good resolution (>1.9 between close eluting solvents) and a shorter run time (20 min). Read More

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Unique reactivity of nanoporous cellulosic materials mediated by surface-confined water.

Nat Commun 2021 05 4;12(1):2513. Epub 2021 May 4.

Department of Chemistry, Institute of Chemistry for Renewable Resources, University of Natural Resources and Life Sciences Vienna (BOKU), Tulln, Austria.

The remarkable efficiency of chemical reactions is the result of biological evolution, often involving confined water. Meanwhile, developments of bio-inspired systems, which exploit the potential of such water, have been so far rather complex and cumbersome. Here we show that surface-confined water, inherently present in widely abundant and renewable cellulosic fibres can be utilised as nanomedium to endow a singular chemical reactivity. Read More

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Solubility and Stability of Some Pharmaceuticals in Natural Deep Eutectic Solvents-Based Formulations.

Molecules 2021 Apr 30;26(9). Epub 2021 Apr 30.

Natural Products Laboratory, Institute of Biology Leiden, Leiden University, 2333 Leiden, The Netherlands.

Some medicines are poorly soluble in water. For tube feeding and parenteral administration, liquid formulations are required. The discovery of natural deep eutectic solvents (NADES) opened the way to potential applications for liquid drug formulations. Read More

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Controlling Nanostructure in Inkjet Printed Organic Transistors for Pressure Sensing Applications.

Nanomaterials (Basel) 2021 Apr 30;11(5). Epub 2021 Apr 30.

Centre for Organic Electronics, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.

This work reports the development of a highly sensitive pressure detector prepared by inkjet printing of electroactive organic semiconducting materials. The pressure sensing is achieved by incorporating a quantum tunnelling composite material composed of graphite nanoparticles in a rubber matrix into the multilayer nanostructure of a printed organic thin film transistor. This printed device was able to convert shock wave inputs rapidly and reproducibly into an inherently amplified electronic output signal. Read More

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Salt-Tolerant Metabolomics for Exometabolomic Measurements of Marine Bacterial Isolates.

Anal Chem 2021 May 4. Epub 2021 May 4.

Institute of Molecular Systems Biology, ETH Zürich, 8093 Zurich, Switzerland.

Identifying and quantifying metabolites secreted by microbial isolates can aid in understanding the physiological traits of diverse species and their interaction with the environment. Mass spectrometry-based metabolomics has potential to provide a holistic view of the exometabolism of marine isolates, but the high salt content of such samples interferes with chromatography and ionization during the measurement of polar exometabolites. The most common desalting methods are faced with major limitations, including limited separation of small polar metabolites from salts, the use of organic solvents that cannot accommodate large salt quantities, and sample throughput. Read More

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Validated green spectrophotometric kinetic method for determination of Clindamycin Hydrochloride in capsules.

BMC Chem 2021 Apr 30;15(1):29. Epub 2021 Apr 30.

Analytical and Food Chemistry Department, Faculty of Pharmacy, University of Aleppo, Aleppo, Syria.

Background: simple, sensitive, free of organic solvents, kinetic spectrophotometric method has been developed for the determination of Clindamycin Hydrochloride, both in pure form and Capsules. Method is based on reaction of Clindamycin with potassium iodide and potassium iodate in an aqueous medium at (25 ± 2 °C) to produce yellow-coloured tri iodide ions (I). The reaction is followed spectrophotometrically by measuring the absorbance at wavelength 350 nm during 40 min. Read More

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Solid-state fermentation production and characterization of an alkaline lipase from a newly isolated strain.

Prep Biochem Biotechnol 2021 May 3:1-10. Epub 2021 May 3.

Embrapa Agroenergia, Parque Estação Biológica - PqEB, Brasília-DF, Brazil.

The newly isolated BRM58833 strain was shown to secrete an alkaline lipase highly active and stable in organic solvents. Lipase production was optimized through the cultivation of the strain by solid-state fermentation in wheat bran. The lipase extraction conditions were also optimized. Read More

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Amide-based deep eutectic solvents containing LiFSI and NaFSI salts as superionic electrolytes for supercapacitor applications.

J Chem Phys 2021 Apr;154(16):164708

Laboratoire PCM2E, Université de Tours, Parc de Grandmont, 37200 Tours, France.

This work proposes two deep eutectic solvents (DESs) based on lithium bis(fluorosulfonyl)imide and sodium bis(fluorosulfonyl)imide together with N-methylacetamide and formamide as electrolytes for activated carbon (AC) electrochemical double-layer capacitors (EDLCs) at 25 °C. The formulated DESs exhibit a large electrochemical window (ΔE > 2.5 V), good thermal stability (∼150 °C) and ionic conductivity (3-4 mS cm), and moderate viscosity (11. Read More

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