338,252 results match your criteria Organic & biomolecular chemistry[Journal]


DUckCov: a Dynamic Undocking-based Virtual Screening Protocol for Covalent Binders.

ChemMedChem 2019 Feb 20. Epub 2019 Feb 20.

Research Center for Natural Sciences, Medicinal Chemistry, Magyar tudosok krt 2, H-1117, Budapest, HUNGARY.

Thanks to recent guidelines, the design of safe and effective covalent drugs has gained significant interest. Other than targeting non-conserved nucleophilic residues, optimizing the non-covalent binding framework is important to improve potency and selectivity of covalent binders towards the desired target. Strong efforts have been made in extending the computational toolkits to include a covalent mechanism of protein targeting, like in the development of covalent docking methods for binding mode prediction. Read More

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http://dx.doi.org/10.1002/cmdc.201900078DOI Listing
February 2019
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Recent Advances of MOF-Derived Nanoporous Carbon Materials.

Chem Asian J 2019 Feb 20. Epub 2019 Feb 20.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD 4072, Australia, AUSTRALIA.

Metal-organic frameworks (MOFs)-derived nanoporous carbon materials have received significant interest due to their advantages of controllable porosity, good thermal/chemical stability, high electrical conductivity, catalytic activity, easy modification with other elements and materials, etc. Thus, MOF-derived carbons have been used in numerous applications such as environment, energy storage systems (i.e. Read More

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http://doi.wiley.com/10.1002/asia.201900026
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http://dx.doi.org/10.1002/asia.201900026DOI Listing
February 2019
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Hierarchical Microchannel Architecture in Chitosan/Bioactive Glass Scaffolds via Electrophoretic Deposition Positive-Replica.

J Biomed Mater Res A 2019 Feb 20. Epub 2019 Feb 20.

Department of Chemistry, Materials and Chemical Engineering "G. Natta", Politecnico di Milano, Milano, Italy.

One of the main challenges in the design of scaffolds for cortical bone regeneration is mimicking the highly oriented, hierarchical structure of the native tissue in an efficient, simple, and consistent way. As a possible solution to this challenge, positive replica based on electrophoretic deposition (EPD) was here evaluated as a technique to produce organic/inorganic scaffolds with oriented micro-porosities mimicking Haversian canals diameter and spacing. Two different sizes of 45S5 bioactive glass (BG) powders were chosen as inclusions and loaded in a chitosan matrix via EPD on micro-patterned cathodes. Read More

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http://dx.doi.org/10.1002/jbm.a.36660DOI Listing
February 2019

Silk Fluorescence Collimator for Ultrasensitive Humidity Sensing and Light-Harvesting in Semitransparent Dye-Sensitized Solar Cells.

Small 2019 Feb 20:e1804171. Epub 2019 Feb 20.

Research Institute for Biomimetics and Soft Matter, College of Materials, College of Physical Science and Technology, Fujian Provincial Key Laboratory for Soft Functional Materials Research, Xiamen University, Xiamen, 361005, China.

This work examines the self-collimation effect of silk materials on fluorescence emission/detection. A macroscopic regulation strategy, coupled with meso-reconstruction and meso-functionalization, is adopted to amplify the fluorescence emission of organic fluorescent dyes (i.e. Read More

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http://dx.doi.org/10.1002/smll.201804171DOI Listing
February 2019

Roles of electrical stimulation in promoting osteogenic differentiation of BMSCs on conductive fibers.

J Biomed Mater Res A 2019 Feb 20. Epub 2019 Feb 20.

School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.

The strategy of using conductive materials in regenerating bone defects is attractive benefiting from the bioelectricity feature of natural bone tissues. Thereby, POP conductive fibers were fabricated by coating polypyrrole (PPY) onto electrospun poly(L-lactide) (PLLA) fibers, and their potentials in promoting osteogenic differentiation of bone mesenchymal stromal cells (BMSCs) were investigated. Different from the smooth-surfaced PLLA fibers, POP fibers were rough-surfaced and favorable for protein adsorption and mineralization nucleation. Read More

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http://dx.doi.org/10.1002/jbm.a.36659DOI Listing
February 2019

Solvent Driven Reversible Phase Transition of Pillared Metal-Organic Framework.

Chemistry 2019 Feb 20. Epub 2019 Feb 20.

Yunnan University, School of Chemical Science and Technology, No.2 North Cuihu Road, 650091, Kunming, CHINA.

During the last decade, the controllable reversible phase transition of functional materials has received growing interest, showing unique performances for various technological applications. Although many metal-organic frameworks (MOFs) possess lamellar structure, the reversible structural transformation of MOFs between three-dimensional (3D) phase and two-dimensional (2D) phase remains a largely unexplored area. Herein, we report for the first time a europium MOFs with unprecedented reversible morphology in the different solvent at room temperature. Read More

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http://dx.doi.org/10.1002/chem.201900406DOI Listing
February 2019

Combination of phytase and citric acid, but not phytase alone, ensures regular rates of growth and bone mineralization in quails under severe phosphorus restriction.

J Anim Physiol Anim Nutr (Berl) 2019 Feb 20. Epub 2019 Feb 20.

College of Veterinary Medicine, Federal University of Mato Grosso, Cuiaba, Brazil.

An experiment was conducted to evaluate the effects of phytase (PHY), alone or in combination with citric acid (CA), on growing Japanese quails under moderate and severe phosphorus (P) restriction. For this, 504 one-day-old female quails were distributed in a completely randomised design with seven treatments and six replications. Treatments consisted of the following diets: (a) positive control (PC): formulated according to quails nutritional requirements; (b) negative control 40% (NC ): PC with 40% less aP; (c) NC +PHY; (d) NC +PHY+CA; (e) negative control 65% (NC ): PC with 65% less aP; (f) NC +PHY; (g) NC +PHY+CA. Read More

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http://dx.doi.org/10.1111/jpn.13074DOI Listing
February 2019

New Organic Electrode Materials for Ultrafast Electrochemical Energy Storage.

Adv Mater 2019 Feb 20:e1806599. Epub 2019 Feb 20.

Helmholtz Institute Ulm, 89081, Ulm, Germany.

Organic materials are both environmentally and economically attractive as potential electrode candidates. This Research News reports on a new class of stable and electrically conductive organic electrodes based on metal porphyrins with functional groups that are capable of electrochemical polymerization, rendering the materials promising for electrochemical applications. Their structural flexibility and the unique highly conjugated macrocyclic structure allows the produced organic electrodes to act as both cathode and anode materials giving access to fast charging as well as high cycling stability. Read More

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http://dx.doi.org/10.1002/adma.201806599DOI Listing
February 2019

2D-Organic Hybrid Heterostructures for Optoelectronic Applications.

Adv Mater 2019 Feb 20:e1803831. Epub 2019 Feb 20.

SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon, 440-746, Republic of Korea.

The unique properties of hybrid heterostructures have motivated the integration of two or more different types of nanomaterials into a single optoelectronic device structure. Despite the promising features of organic semiconductors, such as their acceptable optoelectronic properties, availability of low-cost processes for their fabrication, and flexibility, further optimization of both material properties and device performances remains to be achieved. With the emergence of atomically thin 2D materials, they have been integrated with conventional organic semiconductors to form multidimensional heterostructures that overcome the present limitations and provide further opportunities in the field of optoelectronics. Read More

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http://dx.doi.org/10.1002/adma.201803831DOI Listing
February 2019

Identification of a new inhibitor of KRAS-PDEδ interaction targeting KRAS mutant non-small cell lung cancer.

Int J Cancer 2019 Feb 20. Epub 2019 Feb 20.

State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau (SAR), China.

Oncogenic KRAS is considered a promising target for anti-cancer therapy. However, direct pharmacological strategies targeting KRAS-driven cancers remained unavailable. The prenyl-binding protein PDEδ, a transporter of KRAS, has been identified as a potential target for pharmacological inhibitor by selectively binding to its prenyl-binding pocket, impairing oncogenic KRAS signaling pathway. Read More

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http://dx.doi.org/10.1002/ijc.32222DOI Listing
February 2019

NK007 helps in mitigating paclitaxel resistance through p38MAPK activation and HK2 degradation in ovarian cancer.

J Cell Physiol 2019 Feb 20. Epub 2019 Feb 20.

The First Affiliated Hospital, Biomedical Translational Research Institute and School of Pharmacy, Jinan University, Guangzhou, China.

Ovarian cancer resistance to available medicines is a huge challenge in dire need of a solution, which makes its recurrence and mortality rate further exacerbated. A promising approach to overcome chemoresistance is drug screening from natural products. Here, we report that NK007, a (±)-tylophorine malate isolated from the Asclepiadaceae family, selectively inhibited the proliferation of A2780 and A2780 (Taxol) cells and migration of paclitaxel-sensitive and -resistant ovarian cancer cells. Read More

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http://dx.doi.org/10.1002/jcp.28278DOI Listing
February 2019

Pesticide distribution and depletion kinetic determination in honey and beeswax: Model for pesticide occurrence and distribution in beehive products.

PLoS One 2019 20;14(2):e0212631. Epub 2019 Feb 20.

Department of Toxicology, Kimron Veterinary Institute, Bet Dagan, Israel.

Beehive products such as honey, beeswax and recently pollen have been regarded for many years as appropriate sentinels for environmental pesticide pollutions. However, despite yearly application of hundreds of approved pesticides in agricultural fields, only a minor fraction of these organic compounds were actually detected in honey and beeswax samples. This observation has led us to question the general suitability of beehive products as a sentinel for synthetic organic pesticides applied in the field. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212631PLOS
February 2019

Soil health pilot study in England: Outcomes from an on-farm earthworm survey.

PLoS One 2019 20;14(2):e0203909. Epub 2019 Feb 20.

Sustainable Agricultural Systems Department, Rothamsted Research, Harpenden, United Kingdom.

Earthworms are primary candidates for national soil health monitoring as they are ecosystem engineers that benefit both food production and ecosystem services associated with soil security. Supporting farmers to monitor soil health could help to achieve the policy aspiration of sustainable soils by 2030 in England; however, little is known about how to overcome participation barriers, appropriate methodologies (practical, cost-effective, usefulness) or training needs. This paper presents the results from a pilot #60minworms study which mobilised farmers to assess over >1300 ha farmland soils in spring 2018. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203909PLOS
February 2019

Radical S-Adenosylmethionine Protein NosN Forms the Side Ring System of Nosiheptide by Functionalizing the Polythiazolyl Peptide S-Conjugated Indolic Moiety.

Org Lett 2019 Feb 20. Epub 2019 Feb 20.

State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis , Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences , 345 Lingling Road , Shanghai 200032 , China.

NosN is a radical S-adenosylmethionine protein observed in the biosynthesis of the bicyclic thiopeptide nosiheptide. Insights are provided in terms of the timing of NosN action, its catalytic mechanism, and its role in side ring formation. Beyond being a methyltransferase, NosN transforms a polythiazolyl peptide intermediate by functionalizing the S-conjugated indolic moiety to selectively build a C1 unit, form an ester linkage to the thiopeptide framework, and establish the side ring system specific for nosiheptide. Read More

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http://dx.doi.org/10.1021/acs.orglett.9b00293DOI Listing
February 2019

NBN-embedded Polycyclic Aromatic Hydrocarbons Containing Pentagonal and Heptagonal Rings.

Org Lett 2019 Feb 20. Epub 2019 Feb 20.

Center for Advancing Electronics Dresden (cfaed) & Faculty of Chemistry and Food Chemistry , Technische Universität Dresden , 01062 Dresden , Germany.

Two novel nonhexagonal ring fused NBN-dibenzophenalenes (NBN-penta and NBN-hepta) were designed and synthesized. X-ray analysis reveals the planar structure of NBN-penta, while NBN-hepta displays a double-helical structure. Both compounds possess higher oxidation potential compared to the NBN-type zigzag-edged polycyclic aromatic hydrocarbons. Read More

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http://dx.doi.org/10.1021/acs.orglett.9b00057DOI Listing
February 2019

Electric Field Controlled Magnetization in GaAs/AlGaAs Heterostructures-chiral Organic Molecules Hybrids.

J Phys Chem Lett 2019 Feb 20. Epub 2019 Feb 20.

We study GaAs/AlGaAs devices hosting a two-dimensional electron gas and coated with a monolayer of chiral organic molecules. We observe clear signatures of room temperature magnetism, which is induced in these systems by applying a gate voltage. We explain this phenomenon as a consequence of the spin-polarized charges that are injected into the semiconductor through the chiral molecules. Read More

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http://pubs.acs.org/doi/10.1021/acs.jpclett.9b00092
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http://dx.doi.org/10.1021/acs.jpclett.9b00092DOI Listing
February 2019
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Naphthocage: A Flexible yet Extremely Strong Binder for Singly Charged Organic Cations.

J Am Chem Soc 2019 Feb 20. Epub 2019 Feb 20.

We report a quite flexible naphthol-based cage (so-called "naphthocage") which adopts a self-inclusion conformation in its free state and is able to bind singly charged organic cations extremely strongly (Ka > 107 M-1). Ion-selective electrodes prepared with this naphtocage show a super-Nernstian response to acetylcholine. In addition, the highly stable complex (1010 M-1) between ferrocenium and the naphthocage can be switched elec-trochemically, which lays a basis for its application in stimuli-responsive materials. Read More

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http://dx.doi.org/10.1021/jacs.9b00445DOI Listing
February 2019

Core-Shell Metal-Organic Frameworks As The Mixed-Mode Stationary Phase For Hydrophilic Interaction/Reversed-Phase Chromatography.

ACS Appl Mater Interfaces 2019 Feb 20. Epub 2019 Feb 20.

Stationary phases with mixed-mode mechanisms emerge as a hot research topic. In the present research, monodisperse core-shell UiO-67@SiO2 materials were prepared and further served as the packed column for mixed-mode hydrophilic interaction liquid chromatography/reversed-phase liquid chromatography. The developed UiO-67@SiO2 materials were characterized via thermogravimetric analysis, scanning electron microscopy, X Ray Powder diffraction as well as FT-IR techniques. Read More

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http://dx.doi.org/10.1021/acsami.9b00285DOI Listing
February 2019

Hybrid Organic-Inorganic Thermoelectric Materials and Devices.

Angew Chem Int Ed Engl 2019 Feb 20. Epub 2019 Feb 20.

Wenzhou University, Nano-materials & Chemistry Key Laboratory, Xueyuan Middle Road, 325027, Wenzhou, CHINA.

Hybrid organic-inorganic materials have been considered as a new candidate in the field of thermoelectric materials from the last decade due to their great potential to enhance the thermoelectric performance by utilizing the low thermal conductivity of organic materials and the high Seebeck coefficient, and high electrical conductivity of inorganic materials. Herein, we provide an overview of interfacial engineering in the synthesis of various organic-inorganic thermoelectric hybrid materials, along with the dimensional design for tuning their thermoelectric properties. Interfacial effects are examined in terms of nanostructures, physical properties and chemical doping between the inorganic and organic components. Read More

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http://dx.doi.org/10.1002/anie.201901106DOI Listing
February 2019

3D Lattice Engineering of Nanoparticles by DNA Shells.

Small 2019 Feb 20:e1805401. Epub 2019 Feb 20.

College of Engineering and Applied Sciences, National Laboratory of Solid State Microstructures, Collaborative Innovation Center of Advanced Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University, Nanjing, 210093, China.

With the development of structural DNA nanotechnology, DNA has now far exceeded its original function: as a genetic code. It can, in principle, self-assemble into desired shapes with accurate size. Moreover, it can perform as a functional linker to program other materials by grafting DNA onto these materials. Read More

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http://dx.doi.org/10.1002/smll.201805401DOI Listing
February 2019

Strategies Towards the Synthesis of N2-Substituted 1,2,3-Triazoles.

An Acad Bras Cienc 2019 Feb 14;91(suppl 1):e20180751. Epub 2019 Feb 14.

Biocatalysis and Organic Synthesis Group, Chemistry Institute, Federal University of Rio de Janeiro, 21941-909 Rio de Janeiro, RJ, Brazil.

The chemistry of 1,2,3-triazoles gained much attention since the discovery of the copper catalyzed Alkyne-azide cycloaddition (CuAAC) reaction which delivers exclusively the 1,4-regioisomer in high yields. On the other hand there is still no universal methodology capable of delivering the N2 substituted regioisomer. The unique properties of these N2-substituted 1,2,3-triazoles have stimulated synthetic efforts on the developments of methodologies capable of delivering it in high yield and selectivity. Read More

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http://dx.doi.org/10.1590/0001-3765201820180751DOI Listing
February 2019

A concise synthesis and biological study of evodiamine and its analogues.

Chem Commun (Camb) 2019 Feb 20. Epub 2019 Feb 20.

School of Pharmacy, Lanzhou University, West Donggang Road, No. 199, Lanzhou 730000, China. and Institution State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China.

Efficient access to evodiamine and its analogues is presented via Lewis acid catalysis. In this reaction, three chemical bonds and two heterocyclic-fused rings are constructed in one step. The reaction shows good functional group tolerance and atom economy, and various heteroatom-containing evodiamine analogues are obtained in moderate to excellent yields even on a gram scale. Read More

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http://dx.doi.org/10.1039/c9cc00434cDOI Listing
February 2019

Photocatalytic performance of few-layer graphitic CN: enhanced by interlayer coupling.

Nanoscale 2019 Feb 20. Epub 2019 Feb 20.

New Energy Technology Engineering Laboratory of Jiangsu Province & School of Science, Nanjing University of Posts and Telecommunications (NJUPT), Nanjing 210023, China and Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials (IAM), Jiangsu National Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, Nanjing 210023, China.

For atomically thin two-dimensional materials, van der Waals interlayer coupling is a crucial factor to tune or produce novel physicochemical properties. In terms of photocatalysis, however, researching into the interlayer coupling effect is still in its infancy, especially that involving excited state dynamics. Here, by performing many-body perturbation theory and ab initio nonadiabatic molecular dynamics, we find that metal-free few-layer graphitic C3N4 (g-C3N4) possesses a better photocatalytic hydrogen evolution performance due to interlayer coupling compared with ultrathin monolayer g-C3N4. Read More

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http://dx.doi.org/10.1039/c8nr10142fDOI Listing
February 2019

Charge carrier recombination dynamics in a bi-cationic perovskite solar cell.

Phys Chem Chem Phys 2019 Feb 20. Epub 2019 Feb 20.

Department of Chemistry, Renmin University of China, Beijing 100872, China.

The compositional engineering is of great importance to tune the electrical and optical properties of perovskite and improve the photovoltaic performance of perovskite solar cells. The exploration of the corresponding photoelectric conversion processes, especially the carrier recombination dynamics, will contribute to the optimization of the devices. In this work, perovskite with mixed methylammonium (MA) and formamidinium (FA) as organic cations, MA0. Read More

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http://dx.doi.org/10.1039/c8cp07461eDOI Listing
February 2019

Nanosheets of MIL-53(Al) applied in membranes with improved CO/N and CO/CH selectivities.

Dalton Trans 2019 Feb 20. Epub 2019 Feb 20.

Chemical and Environmental Engineering Department, Instituto de Nanociencia de Aragón (INA) and Instituto de Ciencia de Materiales de Aragón (ICMA), Universidad de Zaragoza-CSIC, 50018 Zaragoza, Spain.

MIL-68(Al) and MIL-53(Al) are carboxylate-based metal-organic frameworks (MOFs) with the same chemical composition but different structures (polymorphs). In this study, MIL-53(Al) nanosheets of ca. 150 nm in size with an average thickness of 3. Read More

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http://dx.doi.org/10.1039/c8dt03774dDOI Listing
February 2019

Equilibrium structures of the tetramezine diastereomers and their ratio: joint analysis of gas phase electron diffraction, quantum chemistry, and spectroscopic data.

Phys Chem Chem Phys 2019 Feb 20. Epub 2019 Feb 20.

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991 Moscow, Russia.

For the first time, we applied a gas-phase electron diffraction (GED) method together with vibrational spectroscopy and quantum chemical calculations to investigate the equilibrium geometries of achiral meso and enantiomeric diastereomers of tetramezine [1,2-bis-(3,3-dimethyldiaziridin-1-yl)ethane] and their ratio in the mixture. In the joint structural analysis of these data, a new approach based on PES parameters is used in the framework of a static molecular model (small amplitude motion approximation). The agreement between the theoretical and experimental molecular intensities is characterized by a divergence factor Rf of 5. Read More

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http://dx.doi.org/10.1039/c8cp07607cDOI Listing
February 2019

Silver-Catalyzed Carboxylative Cyclization of Primary Propargyl Alcohols with CO.

Org Lett 2019 Feb 20. Epub 2019 Feb 20.

Catalysis Research Laboratory (CaRLa) , Im Neuenheimer Feld 584 , Heidelberg 69120 , Germany.

By using silver complexes with bulky ligands such as DavePhos or N-heterocyclic carbenes, propargylic alcohols are smoothly converted with CO into a unique class of unexplored cyclic alkylidene carbonates. These systems, for the first time, also achieve the direct carboxylative cyclization of primary propargylic alcohols. The silver-DavePhos catalyst is further applied for the bis-carboxylative cyclization of primary propargyl derivatives, thereby providing an effective route to a series of previously inaccessible and industrially relevant α-alkylidene cyclic carbonates. Read More

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http://dx.doi.org/10.1021/acs.orglett.9b00156DOI Listing
February 2019

Decarboxylative Cyanation of Aliphatic Carboxylic Acids via Visible-Light Flavin Photocatalysis.

Org Lett 2019 Feb 20. Epub 2019 Feb 20.

Departamento de Química Orgánica, Facultad de Ciencias and Instituto de Síntesis Orgánica (ISO) , Universidad de Alicante , Apdo. 99 , 03080 Alicante , Spain.

An operationally simple method is disclosed for the decarboxylative cyanation of aliphatic carboxylic acids at room temperature. Riboflavin tetraacetate, which is an inexpensive organic photocatalyst, promotes the oxidation of carboxylic acids upon visible-light activation. After decarboxylation, the generated radicals are trapped by TsCN, yielding the desired nitriles without any further additive, in a redox-neutral process. Read More

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http://dx.doi.org/10.1021/acs.orglett.9b00064DOI Listing
February 2019

Electrooxidative Amination of sp C-H Bonds: Coupling of Amines with Aryl Amides via Copper Catalysis.

Org Lett 2019 Feb 20. Epub 2019 Feb 20.

Bioorganic & Biophysical Chemistry Laboratory, Department of Chemistry & Biomedical Sciences and Linnaeus University Centre for Biomaterials Chemistry , Linnaeus University , SE-391 82 Kalmar , Sweden.

Metal-catalyzed cross-coupling reactions are among the most important transformations in organic synthesis. However, the use of C-H activation for sp C-N bond formation remains one of the major challenges in the field of cross-coupling chemistry. Described herein is the first example of the synergistic combination of copper catalysis and electrocatalysis for aryl C-H amination under mild reaction conditions in an atom-and step-economical manner with the liberation of H as the sole and benign byproduct. Read More

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http://dx.doi.org/10.1021/acs.orglett.9b00003DOI Listing
February 2019

Organic Compounds of Actinyls: Systematic Computational Assessment of Structural and Topological Properties in [AnO(CO) ] (An = U, Np, Pu, Am; n = 1-3) Complexes.

Inorg Chem 2019 Feb 20. Epub 2019 Feb 20.

Laser Spectroscopy Laboratory, School of Physics and Electronics Engineering, Collaborative Innovation Center of Extreme Optics , Shanxi University , Taiyuan 030006 , China.

Exploring the bonding features between organics and actinide elements is a fundamental topic in nuclear waste separation. In this work, [AnO(CO) ] (An = U, Np, Pu, and Am; n = 1-3) complexes have been characterized by density functional theory. The actinyl oxalate complexes are found to exhibit the typical An-O, An-O bonds and O-An-O angles. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.8b03538DOI Listing
February 2019

Morphology-Dependent Luminescence in Complex Liquid Colloids.

J Am Chem Soc 2019 Feb 20. Epub 2019 Feb 20.

Department of Chemistry and Institute for Soldier Nanotechnologies , Massachusetts Institute of Technology , 77 Massachusetts Avenue , Cambridge , Massachusetts 02139 , United States.

Complex liquid colloids hold great promise as transducers in sensing applications as a result of their tunable morphology and intrinsic optical properties. Herein, we introduce meta-amino substituted green fluorescence protein chromophore (GFPc) surfactants that localize at the organic-water interface of complex multiphase liquid colloids. The meta-amino GFPc exhibits hydrogen-bonding (HB) mediated fluorescence quenching, and are nearly nonemissive in the presence of protic solvents. Read More

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http://dx.doi.org/10.1021/jacs.8b13215DOI Listing
February 2019

Surface Restraint Synthesis of an Organic-inorganic Hybrid Layer for Dendrite Free Lithium Metal Anode.

ACS Appl Mater Interfaces 2019 Feb 20. Epub 2019 Feb 20.

Li metal is considered to be the most attractive anode for next-generation batteries because of its high specific capacity and low reduction potential. However, uncontrolled Li dendrite growth and low coulombic efficiency cause severe capacity decay and safety issues. Here we propose a LiCl contained inorganic-organic hybrid layer on Li metal surface by a surface restraint dehalogenation reaction, which is highly uniform and features lithiophilic property as well as high ionic conductivity that can inhibit Li dendrite growth effectively. Read More

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http://pubs.acs.org/doi/10.1021/acsami.9b00507
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http://dx.doi.org/10.1021/acsami.9b00507DOI Listing
February 2019
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From Single Molecules to Thin Film Electronics, Nanofibers, e-Textiles and Power Cables: Bridging Length Scales with Organic Semiconductors.

Adv Mater 2019 Feb 20:e1807286. Epub 2019 Feb 20.

Fibre and Polymer Technology, KTH Royal Institute of Technology, 100 44 Stockholm, Sweden.

Organic semiconductors are the centerpiece of several vibrant research fields from single-molecule to organic electronics, and they are finding increasing use in bioelectronics and even classical polymer technology. The versatile chemistry and broad range of electronic functionalities of conjugated materials enable the bridging of length scales 15 orders of magnitude apart, ranging from a single nanometer (10 m) to the size of continents (10 m). This work provides a taste of the diverse applications that can be realized with organic semiconductors. Read More

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http://dx.doi.org/10.1002/adma.201807286DOI Listing
February 2019

Starch deficiency in plant mutants and its influence on photosynthetic and post-photosynthetic carbon isotope fractionations.

J Exp Bot 2019 Feb 9. Epub 2019 Feb 9.

Institute of Agricultural Sciences, ETH Zurich, Universitaetsstrasse, Zurich, Switzerland.

Carbon isotope fractionations occurring during and after photosynthetic CO2 fixation shape the carbon isotope composition (δ13C) of plant material and respired CO2. However, responses of 13C fractionations to diel variation in the leaf starch metabolism are not fully understood. Here we measured δ13C of organic matter (δ13COM), concentrations and δ13C of potential respiratory substrates, δ13C of dark-respired CO2 (δ13CR), and gas-exchange in leaves of starch-deficient plastidial phosphoglucomutase (pgm) mutants and wild type plants of four species (Arabidopsis thaliana, Mesembryanthemum crystallinum, Nicotiana sylvestris, and Pisum sativum). Read More

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http://dx.doi.org/10.1093/jxb/erz045DOI Listing
February 2019

Ni(ii)-doped anionic metal-organic framework nanowire arrays for enhancing the oxygen evolution reaction.

Chem Commun (Camb) 2019 Feb 20. Epub 2019 Feb 20.

School of Chemistry, The University of Melbourne, Parkville, Victoria, 3010, Australia.

Herein, an anionic metal-organic framework nanowire array not only directly grew on Cu foam, but also captured Ni(ii) ions at an ultra-small particle level. The hybrid material exhibited high activity with low overpotential (310 mV at 20 mA cm-2 in 1.0 M KOH solution) toward the oxygen evolution reaction (OER) (1 M KOH), with performance comparable to that of the precious metal benchmark. Read More

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http://dx.doi.org/10.1039/c9cc00009gDOI Listing
February 2019

The aryne Sommelet-Hauser rearrangement.

Chem Commun (Camb) 2019 Feb 20. Epub 2019 Feb 20.

Department of Organic Chemistry, Indian Institute of Science, Bangalore-560012, India.

An aryne induced transition-metal-free and mild Sommelet-Hauser rearrangement of tertiary benzylamines for the synthesis of α-aryl amino acid derivatives in moderate to good yields is presented. Unlike the conventional Sommelet-Hauser rearrangement of ammonium salts, the methodology developed herein requires neither harsh conditions nor strong bases. Moreover, a temperature dependent switchable selectivity for the Sommelet-Hauser and Stevens [1,2] rearrangements has been observed. Read More

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http://dx.doi.org/10.1039/c9cc00629jDOI Listing
February 2019

Hybridization chain reaction-based nanoprobe for cancer cell recognition and amplified photodynamic therapy.

Chem Commun (Camb) 2019 Feb 20. Epub 2019 Feb 20.

Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China.

Precision diagnosis and effective treatment are the cores of early cancer therapy. Here, for the first time, we report a hybridization chain reaction-based nanoprobe for selective and sensitive cancer cell recognition and amplified photodynamic therapy. Read More

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http://dx.doi.org/10.1039/c8cc10074hDOI Listing
February 2019

Advances in porous and nanoscale catalysts for viable biomass conversion.

Chem Soc Rev 2019 Feb 20. Epub 2019 Feb 20.

Centre for Surface Chemistry and Catalysis, Faculty of Bioscience Engineering, KU Leuven, Celestijnenlaan 200f, 3001, Heverlee, Belgium.

Heterogeneous catalysis is a promising technology for the valorization of renewable biomass to sustainable advanced fuels and fine chemicals. Porosity and nanostructure are the most versatile features of heterogeneous solid catalysts, which can greatly determine the accessibility of specific active sites, reaction mechanisms, and the selectivity of desirable products. Hence, the precise tuning of porosity and nanostructure has been a potential strategy towards developing novel solid catalysts with indispensable characteristics for efficient biomass valorization. Read More

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http://dx.doi.org/10.1039/c8cs00452hDOI Listing
February 2019

Assessing the potential of purple phototrophic bacteria for the simultaneous treatment of piggery wastewater and upgrading of biogas.

Bioresour Technol 2019 Feb 16;281:10-17. Epub 2019 Feb 16.

Department of Chemical Engineering and Environmental Technology, School of Industrial Engineering, Valladolid University, Dr. Mergelina, s/n, 47011 Valladolid, Spain; Institute of Sustainable Processes, University of Valladolid, Dr. Mergelina, s/n, 47011 Valladolid, Spain. Electronic address:

The potential of purple phototrophic bacteria (PPB) for the simultaneous treatment of piggery wastewater (PWW) and biogas upgrading was evaluated batchwise in gas-tight photobioreactors. PWW dilution was identified as a key parameter determining the efficiency of wastewater treatment and biomethane quality in PPB photobioreactors. Four times diluted PWW supported the most efficient total organic carbon (TOC) and total nitrogen removals (78% and 13%, respectively), with CH concentrations of 90. Read More

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http://dx.doi.org/10.1016/j.biortech.2019.02.073DOI Listing
February 2019

Fructose as an additional co-metabolite promotes refractory dye degradation: Performance and mechanism.

Bioresour Technol 2019 Feb 10;280:430-440. Epub 2019 Feb 10.

Textile Pollution Controlling Engineering Center of Ministry of Environmental Protection, College of Environmental Science and Engineering, Donghua University, Shanghai 201620, China; Institute of Biosciences, Freiberg University of Mining and Technology, Freiberg 09599, Germany; Biofilm Centre, University Duisburg-Essen, Essen, Germany.

In this work, the performance and mechanism for the boosting effects of fructose as an additional co-metabolite towards the biological treatment of reactive black 5 were systematically investigated. A decolorization efficiency of 98% was obtained in sample FRU200 (with 3 g/L fructose added based on 3 g/L yeast extract), which was 21% higher than that without fructose. Several intermediates with low molecular weight generated in sample FRU200 and different metabolic pathways were deduced. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09608524193024
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http://dx.doi.org/10.1016/j.biortech.2019.02.046DOI Listing
February 2019
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Novel nanocomposite derived from ZnO/CdS QDs embedded crosslinked chitosan: An efficient photocatalyst and effective antibacterial agent.

J Hazard Mater 2019 Feb 10;369:398-407. Epub 2019 Feb 10.

Department of Applied Chemistry, Indian Institute of Technology (ISM), Dhanbad, 826004, India. Electronic address:

A novel nanocomposite (cl-Ch-pMAc@ZnO/CdSQDs) has been developed under microwave irradiation via fabrication of ZnO/CdS quantum dots on anionically functionalized chitosan [i.e. poly (methacrylic acid) crosslinked chitosan (cl-Ch-pMAc) in the presence of diethylene glycol dimethacrylate (DEGDMA) crosslinker]. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.02.022DOI Listing
February 2019

A novel L-Histidine (C, N) codoped-TiO-CdS nanocomposite for efficient visible photo-degradation of recalcitrant compounds from wastewater.

J Hazard Mater 2019 Feb 14;369:384-397. Epub 2019 Feb 14.

Institut fuer Technische Chemie, Leibniz Universität Hannover, Callinstrasse 3, D-30167 Hannover, Germany.

The aim of current study is to synthesis novel visible driven photocatalysts (L-Histidine (C, N) codoped-TiO-CdS) with different loadings of L-Hisitdine (1, 2, and 3 wt.%) and CdS (1:9, 7:1, and 1:5 mass ratios of CdS to TiO). Then, their application for photo-degradation of methyl orange (MO) and biologically treated palm oil mill effluent (POME) were studied. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.02.049DOI Listing
February 2019

In-situ solidification/stabilization of heavy metals contaminated site soil using a dry jet mixing method and new hydroxyapatite based binder.

J Hazard Mater 2019 Feb 11;369:353-361. Epub 2019 Feb 11.

Beijing Zhongyan Technology Co., Ltd., Beijing, 100041, China. Electronic address:

In this study, in-situ treatment using dry jet mixing construction method and SPC (single superphosphate and calcium oxide) new binder are used to solidify/stabilize a heavy metal contaminated site soil with relatively high content of organic matters. Time-dependent field performance of the soils at 41 and 326 days after treatment is evaluated, which includes electrical conductivity (EC), leachability of heavy metals and chemical oxygen demand (COD), soil penetration resistance, acid neutralization capacity (ANC), and chemical speciation of heavy metals. The results indicate that the stabilized soils exhibit satisfactory performance which is comparable with the laboratory study. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.02.031DOI Listing
February 2019
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Physicochemical properties, sensory traits and storage stability of reduced-fat frankfurters formulated by replacing beef tallow with defatted bovine heart.

Meat Sci 2019 Jan 30;151:89-97. Epub 2019 Jan 30.

Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju 52828, Republic of Korea; Institute of Agriculture and Life Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea. Electronic address:

The consumer interests for low-fat meat products are increasing to reduce obesity and chronic diseases. Reduced-fat frankfurter (RFF) was prepared by replacing beef tallow with defatted bovine heart (DBH) produced by supercritical-CO (SC-CO) and hexane. Six different frankfurters i. Read More

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http://dx.doi.org/10.1016/j.meatsci.2019.01.011DOI Listing
January 2019

Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.

Biomed Pharmacother 2019 Feb 19;112:108669. Epub 2019 Feb 19.

Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China; Department of Respiratory Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, 210029, China. Electronic address:

Idiopathic pulmonary fibrosis (IPF) is a progressive and ultimately fatal lung disease with a poor prognosis and limited treatment options. The incidence of IPF increases with age, and the mechanisms related to aging such as cellular senescence have been strongly implicated in disease pathology. Therefore, a better understanding of fibroblasts senescence might provide a new therapeutic strategy to prevent and treat pulmonary fibrosis. Read More

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http://dx.doi.org/10.1016/j.biopha.2019.108669DOI Listing
February 2019

Chemical synthesis, crystal structure, versatile evaluation of their biological activities and molecular simulations of novel pyrithiobac derivatives.

Eur J Med Chem 2019 Feb 14;167:472-484. Epub 2019 Feb 14.

State-Key Laboratory and Research Institute of Elemento-Organic Chemistry, National Pesticide Engineering Research Center (Tianjin), College of Chemistry, Nankai University, Tianjin, 300071, China. Electronic address:

Since pyrithiobac (PTB) is a successful commercial herbicide with very low toxicity against mammals, it is worth exploring its derivatives for an extensive study. Herein, a total of 35 novel compounds were chemically synthesized and single crystal of 6-6 was obtained to confirm the molecular structure of this family of compounds. The novel PTB derivatives were fully evaluated against various biological platforms. Read More

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http://dx.doi.org/10.1016/j.ejmech.2019.02.002DOI Listing
February 2019

UV/chlorine oxidation of the phosphonate antiscalant 1-Hydroxyethane-1, 1-diphosphonic acid (HEDP) used for reverse osmosis processes: Organic phosphorus removal and scale inhibition properties changes.

J Environ Manage 2019 Feb 20;237:180-186. Epub 2019 Feb 20.

Environmental Simulation and Pollution Control State Key Joint Laboratory, State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (SMARC), School of Environment, Tsinghua University, Beijing 100084, PR China; Shenzhen Environmental Science and New Energy Technology Engineering Laboratory, Tsinghua-Berkeley Shenzhen Institute, Shenzhen 518055, PR China. Electronic address:

Reverse osmosis (RO) technology plays an increasingly important role in municipal wastewater reclamation. However, the antiscalants used in RO systems showed adverse effects to the ecosystem: impending the removal of hardness from RO concentrates; inducing phosphorus pollution in receiving water; enhancing the trace metal migration in the environment. In this study, UV/chlorine advanced oxidation process was used to oxidize a typical phosphoric antiscalant (1-Hydroxyethane-1, 1-diphosphonic Acid, HEDP). Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.02.055DOI Listing
February 2019

Carbon-based materials as adsorbent for antibiotics removal: Mechanisms and influencing factors.

J Environ Manage 2019 Feb 19;237:128-138. Epub 2019 Feb 19.

College of Science, Hunan Agricultural University, Changsha, 410128, China.

With the development of the removal of organic pollutants in the soil and water environment, antibiotics have been considered as emerging pollutants and received considerable attention among the scientific community. Thus, there is a need for an effective, economical, fast, operational feasible and environmental-friendly technology to remove antibiotics. Adsorption technology would be one of the most promising option on the basis that it best meets the criteria we set out above. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.02.068DOI Listing
February 2019

Catalytic ozonation of humic acid in water with modified activated carbon: Enhancement and restoration of the activity of an activated carbon catalyst.

J Environ Manage 2019 Feb 18;237:114-118. Epub 2019 Feb 18.

Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, Sichuan Province, PR China.

Catalytic ozonation of organic compounds in water is an important research area for addressing the current pollution crisis. The objective of the present study was to find a modification method for enhancing and restoring the activity of the activated carbon (AC) catalyst applied in the catalytic ozonation of the humic acid (HA) aquatic contaminant. A three-step treatment consisting of an initial thermal treatment, oxidation treatment, and further thermal treatment increased the amount of surface hydroxyl groups (COH) of AC while reducing the amounts of other surface groups, such as basic, carboxyl, lactone, and carbonyl groups. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.02.061DOI Listing
February 2019

Persistent organic pollutants in the polar regions and the Tibetan Plateau: A review of current knowledge and future prospects.

Environ Pollut 2019 Feb 7;248:191-208. Epub 2019 Feb 7.

Key Laboratory of Tibetan Environment Changes and Land Surface Processes, Institute of Tibetan Plateau Research, Chinese Academy of Sciences (CAS), Beijing, 100101, China; CAS Center for Excellence in Tibetan Plateau Earth Sciences, Beijing, 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China.

Due to their low temperatures, the Arctic, Antarctic and Tibetan Plateau are known as the three polar regions of the Earth. As the most remote regions of the globe, the occurrence of persistent organic pollutants (POPs) in these polar regions arouses global concern. In this paper, we review the literatures on POPs involving these three polar regions. Read More

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http://dx.doi.org/10.1016/j.envpol.2019.01.093DOI Listing
February 2019