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Oncology (Williston Park) 2022 Jun;36(6):375-377

A man, aged 21 years, presented with a 4-month history of progressive swelling of the right testicle. Ultrasound revealed a heterogenous solid mass in the right testicle suspicious for malignancy. Further work-up included CT scans, which identified a 2-cm retroperitoneal lymph node; there was no evidence of thoracic metastases. Read More

Asian J Androl 2022 Jun 10. Epub 2022 Jun 10.

Department of Ultrasound, Zhongshan Hospital, Fudan University, Institute of Ultrasound in Medicine and Engineering, Shanghai 200032, China.

The purpose of this study was to evaluate the diagnostic performance of multiparametric ultrasound (mpUS; grayscale US, color Doppler US, strain elastography, and contrast-enhanced US) in the assessment of testicular lesions with negative tumoral markers. MpUS imaging data, patient age, serum tumor markers, scrotal pain, cryptorchidism, and related clinical information were retrospectively collected for patients who underwent mpUS examination between January 2013 and December 2019. Histologic results or follow-up examinations were used as the reference standard. Read More

Cureus 2022 May 6;14(5):e24786. Epub 2022 May 6.

Urology, Royal Commission Yanbu Medical Centre, Yanbu, SAU.

The majority of patients with paratesticular rhabdomyosarcoma (RMS) present in the pediatric age group with a unilateral, painless, palpable scrotum mass. By contrast, cases of RMS presenting as painful edema are rare. We present a case of alveolar paratesticular RMS in a 30-year-old man who had been suffering from a painful swelling of the scrotum on the left side for two years and a preceding mass four months before visiting the clinic. Read More

Int J Surg Case Rep 2022 May 4;94:107167. Epub 2022 May 4.

Pathology Anatomy Department, Hasan Sadikin Academic Medical Center, Universitas Padjadjaran, Bandung, Indonesia.

Introduction An Importance: Testicular epidermoid cysts (TECs) are rare benign testicular neoplasms. Recently, testicular epidermoid cysts (TECs) are listed as teratoma of prepubertal type, however it is still difficult to differentiate the epidermoid cyst from malign testicular tumor. Therefore, we would like to report testicular epidermoid cyst at our institution. Read More

Medicine (Baltimore) 2022 May 6;101(18):e29137. Epub 2022 May 6.

Department of Emergency Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

Introduction: Traumatic testicular dislocation is an uncommon complication of blunt scrotal injury and is easily overlooked because of the presence of other severe accompanying injuries. In most cases, an operation is needed for the prevention of malignant change or infertility.

Patient Concerns And Diagnosis: We report a case of traumatic testicular dislocation with pelvic fracture and internal bleeding in a 27-year-old male with testis rupture after a motorcycle collision. Read More

Urol Case Rep 2022 May 2;42:102020. Epub 2022 Feb 2.

Urology Department, Clínica Santa María, Avenida Sana María 500, Providencia, Región Metropolitana, 7500000, Chile.

Introduction: Retroperitoneal hematomas are rare complications of radical inguinal orchiectomy. This case report discusses their radiological differential diagnosis and management.

Case Presentation: A radical inguinal orchiectomy was performed on a 27-year-old patient. Read More

Eur Urol Open Sci 2022 Jun 26;40:16-18. Epub 2022 Apr 26.

Department of Medical Oncology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.

Incidental detection of urogenital tumors has increased in recent decades owing to the greater use of ultrasonography and cross-sectional imaging. For patients with low-risk prostate cancer or small renal masses, active surveillance represents a valid treatment option. Similarly, for men with small testicular masses <10 mm, active surveillance has been discussed as an alternative to surgery, although little is known regarding the behavior of small testicular germ cell tumors (GCTs). Read More

IJU Case Rep 2022 May 17;5(3):175-178. Epub 2022 Mar 17.

Department of Urology Niigata City General Hospital Niigata Japan.

Introduction: Tumors in the fibroma-thecoma group are benign tumors, typically found in the ovaries of postmenopausal women and occasionally develop in the testes. These tumors are mostly treated with radical orchiectomy because preoperative diagnosis confirming the benign nature is difficult.

Case Presentation: A 40-year-old man was incidentally pointed out to have a right intrascrotal mass, measuring approximately 10 cm on computed tomography. Read More

Rev Int Androl 2022 Apr-Jun;20(2):110-115. Epub 2022 Apr 25.

Hospital Prof. Doutor Fernando Fonseca, Urology Department, IC19, Amadora, Portugal; Hospital Lusíadas de Lisboa, Urology Department, Lisboa, Portugal.

Radical orchiectomy in testicular cancer patients can have a negative impact on body image and self-esteem. Reconstructive surgery with testicular prosthesis might mitigate this burden. We conducted a questionnaire-based study aiming to evaluate our patients' satisfaction with testicular prosthesis. Read More

Case Rep Surg 2022 15;2022:2791305. Epub 2022 Apr 15.

Department of Urology, Loyola University Medical Center, Maywood, IL, USA.

Splenogonadal fusion is a rare congenital anomaly in which ectopic splenic tissue is found in the testis and can present as a testicular mass mimicking a testicular malignancy. We present a 27-year-old male who presented with a palpable left testis mass suspicious for malignancy and ultimately found to have discontinuous splenogonadal fusion after radical orchiectomy. Read More

Cureus 2022 Mar 8;14(3):e22956. Epub 2022 Mar 8.

Second Department of Urology, National and Kapodistrian University of Athens, Sismanogleio General Hospital, Athens, GRC.

Testicular cancer is the most common neoplasm in men aged 15-45 years old, with several established risk factors such as cryptorchidism, age, and family history. We report a case of a 44-year-old man with a history of cryptorchidism who presented with lesions in his right testis, a large retroperitoneal mass, and diffuse nodal lesions in his lungs. He underwent radical orchiectomy that showed testicular cancer and was immediately inducted into systemic therapy based on bleomycin, etoposide, and cisplatin. Read More

J Pediatr Urol 2022 Jun 3;18(3):401-403. Epub 2022 Mar 3.

Pediatric Urology Divion, Urology Department, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, Spain. Electronic address:

Introduction: Paratesticular sarcoma is an aggressive malignant tumor of mesenchymal origin. The rhabdomyosarcoma is the most common among children. Rhabdomyosarcoma treatment consists of surgery, chemotherapy and radiotherapy. Read More

Cureus 2022 Mar 6;14(3):e22885. Epub 2022 Mar 6.

Hematology and Medical Oncology, HCA Houston Healthcare Kingwood Medical Center, Kingwood, USA.

A 25-year-old male presented to our hospital with two months of progressively worsening left arm swelling, intermittent left-sided chest pressure, and a painless right testicular mass. CT of the chest, abdomen, and pelvis revealed a large mediastinal mass, multiple lung nodules, and several large right testicular nodules. The patient underwent a CT-guided biopsy of his right lung nodule, followed by a radical right inguinal orchiectomy. Read More

Cureus 2022 Feb 14;14(2):e22210. Epub 2022 Feb 14.

Urology, Spokane Urology, Spokane, USA.

Adenocarcinoma of the rete testis is an extremely rare and aggressive tumor that carries a poor prognosis. Successful long-term treatment for such tumors remains elusive as more cases are discovered worldwide. Treatment typically involves radical orchiectomy, retroperitoneal pelvic lymph node dissection, adjuvant chemotherapy, and/or continued surveillance. Read More

Int J Surg Case Rep 2022 Apr 9;93:106923. Epub 2022 Mar 9.

Department of Oncology, Aga Khan University, Karachi, Pakistan.

Introduction And Importance: The neoplasms of the testis are sporadic tumors among men. Furthermore, the rarest subset of these is neoplasms belonging to the stromal tumors of the sex cord. Leydig cell tumors are the most common form among the testicular stromal tumors. Read More

Urol Case Rep 2022 Jul 5;43:102049. Epub 2022 Mar 5.

Division of Urology, Cooperman Barnabas Medical Center, Livingston, NJ, USA.

Cystadenoma of the tunica of the adult male testis has rarely been reported in the literature. We report a case of an adult serous cystadenoma along with the radiological and pathological findings. The patient was a 40-year-old male with a slowly growing mass on the left testis. Read More

Am J Case Rep 2022 Mar 15;23:e935521. Epub 2022 Mar 15.

Department of Urology, Oregon Urology Institute, Springfield, OR, USA.

BACKGROUND Prostate cancer is the most common non-cutaneous cancer in men. While approximately three-quarters of all cases present as localized disease, the rate of metastatic disease has been increasing. Common sites of metastatic prostate cancer include regional lymph nodes, bones, and lungs. Read More

Urol Case Rep 2022 Jul 7;43:102048. Epub 2022 Mar 7.

Laboratório Bacchi, 1191 Maestro Cardim St. - Bela Vista, São Paulo, SP, 01323-001, Brazil.

Mesotheliomas of the tunica vaginalis testis are very uncommon tumors, with rare cases published in the literature. This report demonstrates a case in with such a tumor was diagnosed in a 50-year-old man who presented to the emergency room with mild, acute scrotal pain and swelling, without previously known scrotal pathology. It is noted that sonographers should be aware of the typical characteristics that allow for suspecting malignancy in scrotal sonography performed in the emergency setting; this was particularly important in this case. Read More

Int J Surg Pathol 2022 Mar 7:10668969221085292. Epub 2022 Mar 7.

159442Hangzhou Children's Hospital, Hangzhou, China.

Androgen insensitivity syndrome (AIS) is a disorder of sexual differentiation caused by complete or partial resistance to the biological action of androgens. The common malignant tumors associated with this syndrome are seminomas. However, the risk of malignancy in childhood remains low. Read More

Clin Case Rep 2022 Mar 1;10(3):e05511. Epub 2022 Mar 1.

Department of Urology Neyshabur University of Medical Sciences Neyshabur Iran.

Epididymal leiomyosarcoma (LMS) is a rare malignancy. Because the risk of recurrence is high, proper approach is important. Here, we present a patient with scrotal swelling who underwent surgical excision via scrotal incision, and the histopathological diagnosis was epididymal LMS. Read More

Cureus 2022 Jan 25;14(1):e21612. Epub 2022 Jan 25.

Urology, New Jersey Urology, Voorhees, USA.

Fournier's gangrene and emphysematous pyelonephritis are rare necrotizing infections of the genitourinary system. Many cases of this rapidly progressive infection occur from abscesses and urinary tract infections; however, Fournier's gangrene secondary to emphysematous pyelonephritis is seldom discussed in the literature. Emphysematous pyelonephritis is defined as a gas-forming, necrotizing infection of the renal parenchyma or its surrounding tissue. Read More

Cureus 2022 Jan 25;14(1):e21603. Epub 2022 Jan 25.

Department of Radiation Oncology, Iran University of Medical Sciences, Tehran, IRN.

Spontaneous primary tumor regression, or burned-out tumors, refers to the presence of a metastatic tumor with the histological regression of the primary lesion. The burned-out phenomenon has been reported in various malignancies, with testicular germ cell tumors (GCTs) accounting for a significant share of these cases. However, burned-out testicular tumors are a rare clinical phenomenon and are generally difficult to diagnose, as there is no evidence of primary testicular cancer. Read More

World J Clin Oncol 2022 Jan;13(1):62-70

Hematology/Oncology, UCI Medical Center, University of California, Orange, CA 92868, United States.

Background: Late relapses of early-stage germ cell tumors are rare. Most patients (-85%) with stage I seminoma are cured by radical orchiectomy. The detection of late relapse is challenging given the relative rarity of this phenomenon, and the fact that patients who have completed surveillance are usually not undergoing regular oncologic workup nor imaging. Read More

Hinyokika Kiyo 2022 Jan;68(1):17-21

The Department of Urology, Saiseikai Yokohamashi Nanbu Hospital.

A 52-year-old man was referred to our hospital for evaluation of painless right scrotal swelling persisting for 3 months. Palpation detected swelling and induration centered on the head of the upper epididymis, and ultrasonography revealed a blood-filled nodular mass at the same site continuing to the spermatic cord. No abnormalities were observed in the bilateral testes. Read More

Cureus 2021 Dec 27;13(12):e20764. Epub 2021 Dec 27.

Hematology/Oncology, Brooke Army Medical Center, San Antonio, USA.

Testicular cancer is considered to be the model for the curable neoplasm, with outcomes improving from nearly universal fatality to nearly universal cure in the matter of two decades, driven largely in part by the accidental discovery and application of platinum chemotherapy. Such a diagnosis and treatment can have significant and long-lasting effects on patients, although with every such experience come learning opportunities. This autobiographical case report describes the author's experience being diagnosed with testicular cancer, the challenges faced during treatment and survivorship, the lessons learned being a patient, and the way they guided him on his path to his current role as an adolescent and young adult (AYA) oncologist. Read More

Ann R Coll Surg Engl 2022 Feb;104(2):32-34

Chelsea and Westminster Hospital, London, UK.

Splenogonadal fusion is a rare benign congenital anomaly in which there is an abnormal connection between the gonad and the spleen. It was first described over 100 years ago with limited reports in the literature since then. Its similarity in presentation to testicular neoplasia poses a significant challenge in diagnosis and management, often resulting in radical orchidectomy. Read More

Oncology (Williston Park) 2021 12 17;35(12):816-819. Epub 2021 Dec 17.

Hematology-Oncology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.

The case An 18-year-old male presented with a one-month history of a nonpainful right testicular enlargement. He had no family history of neoplasia, nor any relevant past medical history. The physical examination was only remarkable for an enlarged right testicle. Read More

Front Immunol 2021 10;12:720359. Epub 2022 Jan 10.

Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background: Testicular sex cord stromal tumours (TSCSTs) are rare, with few studies focusing on the metastatic TSCST prognosis. The value of treatments, including radical orchiectomy (RO) and retroperitoneal lymph node dissection (RPLND), in preventing metastasis is controversial. Additionally, metastatic TSCSTs are resistant to chemotherapy. Read More

Cureus 2021 Dec 19;13(12):e20517. Epub 2021 Dec 19.

General Surgery, Kantonsspital St. Gallen, Saint Gallen, CHE.

Fournier's gangrene (FG) is an atypical, life-threatening polymicrobial infection characterized by the rapid destruction of soft tissue, predominantly in the perineal region. Retroperitoneal spread of FG represents an uncommon condition described in a few case reports, and its presentation as the first manifestation of the human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) is even more infrequent. Here, we present the case of a 40-year-old male who was admitted to the emergency department with a low-grade fever of 37. Read More

Transplant Proc 2022 Jan-Feb;54(1):126-127. Epub 2022 Jan 7.

Department of Surgery, Tulane School of Medicine, New Orleans, Louisiana.

There is a paucity of literature on testicular complications after kidney transplant. Testicular necrosis after kidney transplantation has only been reported twice before. We present a 60- year-old man with end-stage renal disease who underwent uneventful deceased-donor kidney transplant. Read More