466 results match your criteria Orchiectomy Partial


Large-cell calcifying Sertoli cell tumour with macrocalcification in partially resected testis of young adult patient.

Malays J Pathol 2018 Dec;40(3):343-348

University of Niš Faculty of Medicine, Scientific Research Centre for Biomedicine, Serbia, Zoran Đinđic Boulevard 81, 18000 Niš, Serbia.

Introduction: There are less than 100 cases of Large-cell calcifying Sertoli cell tumour (LCCSCT) reported in English literature. Most of them are benign, bilateral and affect paediatric population. Malignant cases occur in older patients. Read More

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December 2018
3 Reads

Appropriateness for testis-sparing surgery based on the testicular tumor size in a pediatric and adolescent population.

J Pediatr Urol 2018 Oct 23. Epub 2018 Oct 23.

Division of Pediatric Urology, Children's Hospital Colorado and Division of Urology, Department of Surgery, University of Colorado School of Medicine, Aurora, CO, USA. Electronic address:

Introduction: In children, most small testicular tumors are benign, and testicular-sparing surgery (TSS) is a viable treatment option.

Objective: The objective of this study is to assess for correlation between the tumor size and final pathologic diagnoses appropriate for TSS for pediatric and adolescent patients with an intratesticular mass and negative serum tumor markers (STMs).

Materials And Methods: A retrospective review of 24 patients (aged 0-18 years) who underwent radical or partial orchiectomy between 2003 and 2015. Read More

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http://dx.doi.org/10.1016/j.jpurol.2018.10.011DOI Listing
October 2018

[Tunica albuginea adenomatoid tumor. A challenging case managed conservatively].

Rev Int Androl 2018 Apr - Jun;16(2):82-86. Epub 2017 May 2.

Anatomia Patológica, Laboratório Anatomia Patológica (LAP), Porto, Portugal.

The adenomatoid tumors are rare benign mesothelial lesions that in males affect mainly the epididymis. They account for over one third of paratesticular tumors, and the treatment of choice has been surgical excision. The origin in testicular parenchyma or the tunica albuginea is extremely rare. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1698031X173003
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http://dx.doi.org/10.1016/j.androl.2017.02.008DOI Listing
May 2017
2 Reads

Ultrasonographic features of testicular metastasis from renal clear cell carcinoma that mimics a seminoma: A case report.

Medicine (Baltimore) 2018 Oct;97(40):e12728

Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Rationale: Testicular metastases from renal cell carcinoma (RCC) are extremely rare. To the best of our knowledge, only 35 cases have been described in the literatures.

Patient Concerns: A 64-year-old male presented to our urology clinic for a palpable painless mass on his right side of the scrotum by self-examination 1 week ago, with a general abdominal ultrasonographic report showing a mass in his right kidney. Read More

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http://dx.doi.org/10.1097/MD.0000000000012728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200504PMC
October 2018
2 Reads

Testicular tumours discovered during infertility workup are predominantly benign and could initially be managed by sparing surgery.

J Surg Oncol 2018 Sep 9;118(4):630-635. Epub 2018 Sep 9.

Urology Department, Robert Picqué Hospital, Villenave d'Ornon, France.

Background And Objectives: To evaluate the pathological features and recurrence of incidental testis tumours treated by partial orchiectomy in a population of infertile men.

Methods: We retrospectively pooled, from four andrology referral centres, 32 patients diagnosed with testis mass during regular infertility workup. Patients included had an impaired sperm analysis and testis sparing surgery was performed to prevent secondary azoospermia or androgen therapy. Read More

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http://doi.wiley.com/10.1002/jso.25203
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http://dx.doi.org/10.1002/jso.25203DOI Listing
September 2018
11 Reads

Testicular cavernous hemangioma associated with testicular torsion - case report and review of literature.

Int J Surg Case Rep 2018 27;49:247-250. Epub 2018 Jun 27.

Department of Pediatric and Adolescent Surgery, General Hospital, Klagenfurt, Austria. Electronic address:

Introduction: Testicular neoplasms that are derived from connective tissue, blood vessels and musculature are uncommon and intra-testicular tumors of vascular origin are extremely rare; both are benign in nature. Testicular hemangioma is exceedingly rare and typically occurs in patients younger than 20 years, the age in which a primary germ cell tumor of the testis may present, necessitating a radical approach to management with orchidectomy, although potential conservative focal partial surgical excision is desirable. Hemangiomas of the testis have a similar sonographic and magnetic resonance imaging appearance to that of malignant tumors of the testis, especially seminoma. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080632PMC
June 2018
3 Reads

[Non-palpable testicular tumors in adults: A management based on imaging? Issue from the French Urologic Association Genital Cancer committee's edit].

Prog Urol 2018 Jun 9;28(8-9):407-415. Epub 2018 Apr 9.

Hôpital IA Begin/Val-de-Grâce, 74, boulevard de Port-Royal, 75230 Paris, France.

Background: Help in management of non-palpable testicular tumors. French Urologic Association Genital cancer committee's Edit.

Objectives: To review their characterization at imaging findings of non-palpable testicular tumors. Read More

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http://dx.doi.org/10.1016/j.purol.2018.03.007DOI Listing
June 2018
1 Read

Prepubertal Malignant Large Cell Calcifying Sertoli Cell Tumor of the Testis.

Urology 2018 Jul 4;117:145-149. Epub 2018 Apr 4.

Department of Pathology, University of Michigan, Ann Arbor, MI. Electronic address:

An otherwise healthy 7-year-old boy was diagnosed with malignant large cell calcifying Sertoli cell tumor (LCCSCT) of the testis. He underwent attempted partial orchiectomy with conversion to radical orchiectomy due to suspected malignancy on intraoperative frozen section. There was no lymph node or visceral metastases. Read More

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http://dx.doi.org/10.1016/j.urology.2018.03.033DOI Listing
July 2018
2 Reads

Spectrum of findings in orchiectomy specimens of persons undergoing gender confirmation surgery.

Hum Pathol 2018 Jun 17;76:91-99. Epub 2018 Mar 17.

Department of Pathology and Laboratory Medicine, Rhode Island Hospital, Providence, RI 02903, USA.

Gender confirmation surgery is increasingly common in persons with gender dysphoria. We describe changes seen in gonads from individuals seeking male-to-female physical adaptation. We studied 99 orchiectomies from 50 persons. Read More

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http://dx.doi.org/10.1016/j.humpath.2018.03.007DOI Listing
June 2018
8 Reads
2.770 Impact Factor

Testicular Cancer Presenting as Gastric Variceal Hemorrhage.

Case Rep Gastrointest Med 2017 6;2017:4510387. Epub 2017 Nov 6.

Department of Internal Medicine, University Hospital "Dr. José Eleuterio González" and Faculty of Medicine, Universidad Autónoma de Nuevo León, Monterrey, NL, Mexico.

Testicular cancer is the most common solid malignancy affecting males between the ages of 15 and 35. The symptomatology caused by this tumor varies according to the site of metastasis. We present the case of a 26-year-old male who arrived to the emergency department with hematemesis. Read More

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http://dx.doi.org/10.1155/2017/4510387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695022PMC
November 2017
22 Reads

Intratesticular calcified nodule.

Turk J Urol 2017 Dec 1;43(4):563-565. Epub 2017 Dec 1.

Clinic of Pathology, Ankara Atatürk Training and Research Hospital, Ankara, Turkey.

Since calcified nodule of the testis is seen very rarely, its etiology and diagnostic approach are not fully known. There have been a few cases reported in the literature. The objective of this study was to review the literature and report the case of a 30-year-old patient, who applied to our clinic due to a suspicious stiffness in his testis and underwent partial orchiectomy. Read More

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http://turkishjournalofurology.com/eng/makale/3112/168/Full-
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http://dx.doi.org/10.5152/tud.2017.94580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687227PMC
December 2017
6 Reads

Post-operative outcomes of surgical and chemical castration with zinc gluconate in dogs presenting to veterinary field clinics.

Vet J 2017 Nov 6;229:26-30. Epub 2017 Nov 6.

Universidad Central del Ecuador, Facultad de Medicina Veterinaria y Zootecnica, Ciudadela Universitaria Av. América, Quito, Ecuador.

The objective of this study was to characterize post-operative outcomes of chemical castration as compared to surgical castration performed by existing municipal field clinics. Fifty-four healthy adult male dogs underwent chemical castration with zinc gluconate solution and 55 healthy adult male dogs underwent surgical castration in veterinary field clinics. Dogs in each group were evaluated for swelling, inflammation, and ulceration (chemical castration) or dehiscence (surgical castration) at Days 3, 7, and 14 following castration. Read More

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http://dx.doi.org/10.1016/j.tvjl.2017.10.016DOI Listing
November 2017
38 Reads

Burned-Out Testicular Cancer: Really a Different History?

Case Rep Oncol 2017 Sep-Dec;10(3):846-850. Epub 2017 Sep 20.

Policlinico Umberto I, Rome, Italy.

Two or more histological types characterize more than 60% of testicular germ cell tumors (GCTs). Burned-out testicular tumor refers to partial or complete histological regression of the primary testicular lesions. The most frequent GCT type involved in this kind of histological regression is choriocarcinoma, followed by embryonal carcinoma. Read More

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http://dx.doi.org/10.1159/000480493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649263PMC
September 2017
10 Reads

Incidentally detected testicular lesions <10 mm in diameter: can orchidectomy be avoided?

BJU Int 2018 04 12;121(4):575-582. Epub 2017 Nov 12.

Barts Cancer Institute, Queen Mary University of London, London, UK.

Objective: To investigate the pathology of excised testicular lesions <10 mm in size.

Patients And Methods: The pathological reports of 2 681 patients with testicular lesions from Barts Health NHS Trust and Oxford University Hospitals NHS Foundation Trust were reviewed as part of a service evaluation audit from January 2003 to May 2016. Cases in which the lesion had a maximum diameter of <10 mm were selected. Read More

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http://dx.doi.org/10.1111/bju.14056DOI Listing
April 2018
10 Reads

Testicular epidermoid cyst: A rare case.

Urol Ann 2017 Jul-Sep;9(3):296-298

Department of Urology, Florida Atlantic University, Charles E. Schmidt College of Medicine, Boca Raton Regional Hospital, Boca Raton, FL, USA.

Testicular epidermoid cysts are a rare cause of testicular pathology. No cases of recurrence or metastasis have been reported in the literature. As a result, inguinal partial orchiectomy with frozen section has recently become standard treatment. Read More

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http://dx.doi.org/10.4103/UA.UA_37_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532904PMC
August 2017
6 Reads

Organ-sparing surgery for large cell calcifying Sertoli cell tumour in a patient with Carney complex.

BMJ Case Rep 2017 Jul 14;2017. Epub 2017 Jul 14.

Serviço de Urologia e Transplantação Renal, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Carney complex is a rare genetic disease characterised by a complex of myxomas, spotty pigmentation and endocrine overactivity. At diagnosis, about one-third of male patients presents with testicular tumours, namely large cell calcifying Sertoli cell tumours, which are often multicentric and/or bilateral and have a low malignant potential. Although radical orchiectomy is the gold standard for the treatment of testicular neoplasms, a conservative approach with partial orchiectomy or tumourectomy may be the best treatment option for these patients, allowing the preservation of endocrine function, fertility and body image. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2017-21955
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http://dx.doi.org/10.1136/bcr-2017-219557DOI Listing
July 2017
22 Reads

Alfaxalone for maintenance of anaesthesia in ponies undergoing field castration: continuous infusion compared with intravenous boluses.

Vet Anaesth Analg 2017 Jul 14;44(4):832-840. Epub 2017 Apr 14.

Davies Veterinary Specialists, Higham Gobion, UK.

Objective: To compare alfaxalone as continuous intravenous (IV) infusion with intermittent IV injections for maintenance of anaesthesia in ponies undergoing castration.

Study Design: Prospective, randomized, 'blinded' clinical study.

Animals: A group of 33 entire male Welsh ponies undergoing field castration. Read More

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http://dx.doi.org/10.1016/j.vaa.2016.06.004DOI Listing
July 2017
6 Reads

Detection and quantification of Ra uptake in bone metastases of patients with castration resistant prostate carcinoma, with the aim of determining the absorbed dose in the metastases.

Rev Esp Med Nucl Imagen Mol 2018 Jan - Feb;37(1):20-27. Epub 2017 Jun 20.

Servicio de Medicina Nuclear, Hospital Universitario Cruces-Gurutzeta, Barakaldo, España.

Purposes: To obtain the necessary acquisition and calibration parameters in order to evaluate the possibility of detecting and quantifying Ra uptake in bone metastases of patients treated for castration resistant prostate carcinoma. Furthermore, in the cases in which the activity can be quantified, to determine the absorbed dose.

Material And Methods: Acquisitions from a Petri dish filled with Ra were performed in the gamma camera. Read More

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http://dx.doi.org/10.1016/j.remn.2017.04.009DOI Listing
September 2018
1 Read

Testosterone Modifies Alterations to Detrusor Muscle after Partial Bladder Outlet Obstruction in Juvenile Mice.

Front Pediatr 2017 7;5:132. Epub 2017 Jun 7.

Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.

Lower urinary tract symptoms secondary to posterior urethral valves (PUV) arise in boys during adolescence. The reasons for this have previously been attributed to increased urine output as boys experience increased growth. Additionally, there are few choices for clinicians to effectively treat these complications. Read More

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http://dx.doi.org/10.3389/fped.2017.00132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461247PMC
June 2017
11 Reads

Benign Large-cell Calcifying Sertoli Tumor of the Testis in a 13-Year-Old Male Patient Treated With Partial Orchiectomy.

Urology 2017 Sep 24;107:226-228. Epub 2017 May 24.

Department of Pediatric Urology, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA.

Large-cell calcifying Sertoli cell tumor (LCCSCT) of the testis is an exceptionally rare lesion, found sparsely in any medical literature. There is a correlation between this entity and Peutz-Jeghers syndrome and Carney complex (40% of tumors). The remaining 60% of tumors are sporadic. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00904295173051
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http://dx.doi.org/10.1016/j.urology.2017.05.023DOI Listing
September 2017
24 Reads

Incidence of Low-Grade Testicular Injury in Orchidectomy Specimens Post-testicular Torsion.

Eur J Pediatr Surg 2018 Oct 15;28(5):433-438. Epub 2017 May 15.

Department of Paediatric Surgery, Children's University Hospital, Dublin, Ireland.

Introduction:  Following detorsion and orchidopexy for testicular torsion, predominantly animal studies have reported a risk of autoimmune and reperfusion injury to the contralateral testis. As a result, when testicular viability is compromised, orchidectomy is readily performed. This practice increases the likelihood of testes with potentially reversible injury being excised. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1603091
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http://dx.doi.org/10.1055/s-0037-1603091DOI Listing
October 2018
7 Reads

Sex effects on net protein and energy requirements for growth of Saanen goats.

J Dairy Sci 2017 Jun 23;100(6):4574-4586. Epub 2017 Mar 23.

Department of Animal Sciences, Universidade Estadual Paulista, Jaboticabal, SP 14884-900, Brazil. Electronic address:

Requirements for growth in the different sexes remain poorly quantified in goats. The objective of this study was to develop equations for estimating net protein (NP) and net energy (NE) for growth in Saanen goats of different sexes from 5 to 45 kg of body weight (BW). A data set from 7 comparative slaughter studies (238 individual records) of Saanen goats was used. Read More

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http://dx.doi.org/10.3168/jds.2016-11895DOI Listing

Differences in textural properties of cooked caponized and broiler chicken breast meat.

Poult Sci 2017 Jul;96(7):2491-2500

National Center for Genetic Engineering and Biotechnology (BIOTEC), 113 Thailand Science Park, Phahonyothin Rd., Khlong Nueng, Khlong Luang, Pathum Thani 12120, Thailand.

This study was aimed at evaluating textural properties of cooked chicken breast meats obtained from 3 production systems (conventional raising, feed modification, and caponization) and determining the relationship between instrumental parameters and sensory attributes associated with the texture of capon meat. Texture of cooked breast meats was determined using 3 instrumental methods: Warner-Bratzler Shear (WBS), texture profile analysis (TPA), and uniaxial compression (UC), and sensory analysis by trained panelists. The results indicated that cooked caponized meat showed the lowest values of WBS force, shear energy, hardness, Young's modulus of UC, and the 2 sensory attributes (firmness and number of chews) (P < 0. Read More

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http://dx.doi.org/10.3382/ps/pex006DOI Listing

Evaluation of the decision-making process in the conservative approach to small testicular masses.

Urologia 2017 Apr 15;84(2):83-87. Epub 2017 Mar 15.

Department of Urology "L. Giuliani", San Martino Hospital, University of Genova, Genova - Italy.

Introduction: We evaluate the clinical outcome of patients treated with conservative approach for small testicular masses (STMs). We analyzed the steps who brought to the selection of the therapeutic approach: starting from clinical presentation, through imaging and lab studies.

Methods: We considered 18 patients who underwent an organ-sparing approach for STMs from 2005 until 2014. Read More

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http://dx.doi.org/10.5301/uro.5000219DOI Listing

[Pulmonary Mycobacterium Avium-Complex (MAC) Disease Differentially Diagnosed from Metastasis of Testicular Cancer : A Case Report].

Hinyokika Kiyo 2017 Jan;63(1):31-34

The Department of Urology and Kidney Transplantation, Yokohama City University Medical Center.

A 45 year-old-man was admitted to our hospital because of discomfort in his left scrotum. He had a left testicular tumor. We performed high orchiectomy and pathological findings revealed testicular cancer. Read More

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http://dx.doi.org/10.14989/ActaUrolJap_63_1_31DOI Listing
January 2017
14 Reads

Microsurgical identification and excision of an intratesticular mass.

Fertil Steril 2017 Apr 24;107(4):e16. Epub 2017 Feb 24.

Department of Urology, University of Miami Miller School of Medicine, Miami, Florida; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida. Electronic address:

Objective: To demonstrate a step-by-step approach to microsurgical partial orchiectomy (PO) in a man with a small intratesticular mass.

Design: Video presentation.

Setting: University hospital. Read More

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http://dx.doi.org/10.1016/j.fertnstert.2017.01.012DOI Listing
April 2017
7 Reads

Testis sparing surgery for treatment of small testicular lesions: Is it feasible even in germ cell tumors?

J Surg Oncol 2017 Mar 13;115(3):287-290. Epub 2017 Feb 13.

Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

Background And Objectives: To evaluate the results of testis-sparing surgery (TSS) in patients, with small testicular lesions and a normal contralateral testicle.

Methods: In all, 28 patients were treated with TSS for small testicular lesions and a normal contralateral testicle. TSS was considered in patients with testicular lesions smaller than 2 cm and no evidence of metastatic disease. Read More

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http://dx.doi.org/10.1002/jso.24502DOI Listing
March 2017
15 Reads

Clinical benefits of frozen section assessment during urological surgery: Does it contribute to improving surgical margin status and patient outcomes as previously thought?

Authors:
Hiroshi Miyamoto

Int J Urol 2017 01 8;24(1):25-31. Epub 2016 Nov 8.

Departments of Pathology and Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Despite significant advances in patient selection as well as surgical technique over the past few decades, it is still not uncommon for patients with urological malignancy and positive surgical margins to be observed. Meanwhile, intraoperative pathology consultation with frozen section assessment, which generally provides useful information for the optimal procedure, has been widely utilized for the assessment of surgical margins during urological surgeries. Thus, it remains unanswered whether intraoperative frozen section assessment has an impact on final surgical margin status as well as long-term oncological outcomes. Read More

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http://dx.doi.org/10.1111/iju.13247DOI Listing
January 2017
6 Reads

Anti-Muellerian hormone, inhibin A, gonadotropins, and gonadotropin receptors in bull calves after partial scrotal resection, orchidectomy, and Burdizzo castration.

Theriogenology 2017 Jan 7;87:242-249. Epub 2016 Sep 7.

Obstetrics, Gynecology and Andrology, Department for Small Animals and Horses, University of Veterinary Medicine, Vienna, Austria.

Eight-week-old calves were either castrated by partial scrotal resection (SR) without removing the testes (n = 10), Burdizzo (BZ) clamp (n = 10), orchidectomy (OR; n = 10), or were left gonad intact as controls (CO; n = 10). Concentrations of anti-Muellerian hormone (AMH), inhibin A, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) in plasma were determined from 16 to 48 weeks of age. At 18 months, testes of SR, BZ, and CO bulls were obtained and the immunolocalization of LH and FSH receptors and AMH analyzed. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2016.08.030DOI Listing
January 2017
11 Reads

Endobronchial metastasis of mixed germ cell tumors: two cases.

Tuberk Toraks 2016 Jun;64(2):175-8

Clinic of Interventional Pulmonology, Ankara Ataturk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Turkey.

Lung metastases from extrapulmonary malignancies are common however endobronchial metastases (EBM) from nonpulmonary neoplasms are rare. A variety of extrathoracic tumors have a tendency to EBM especially breast, colon, and renal carcinomas are most frequent reported tumors however EBM of germ cell tumors are extremely rare. A 39-year-old and a 27-year-old male patient were admitted to our hospital with hemoptysis and dyspnea at different times. Read More

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June 2016
2 Reads
1 Citation

Idiopathic abdominal cocoon syndrome with unilateral abdominal cryptorchidism and greater omentum hypoplasia in a young case of small bowel obstruction.

World J Gastroenterol 2016 May;22(20):4958-62

Xiang Fei, Hai-Rui Yang, Peng-Fei Yu, Guo-Li Gu, Department of General Surgery, the Air Force General Hospital, Chinese PLA, Beijing 100142, China.

Abdominal cocoon syndrome (ACS) is a rare cause of intestinal obstruction due to total or partial encapsulation of the small intestine by a fibrocollagenous membrane. Idiopathic ACS with abdominal cryptorchidism and greater omentum hypoplasia is even rarer clinically. We successfully treated a 26-year-old male case of small bowel obstruction with acute peritonitis. Read More

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http://dx.doi.org/10.3748/wjg.v22.i20.4958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873888PMC
May 2016
5 Reads

Successful hematopoietic stem cell mobilization with vinorelbine and filgrastim in germ cell tumor.

Clin Exp Med 2017 Aug 10;17(3):417-418. Epub 2016 May 10.

Hematology Division, Walter Cantidio University Hospital, Federal University of Ceara, Rua Capitão Francisco Pedro, 1290. Rodolfo Teofilo, Fortaleza, CE, 60.430-270, Brazil.

Germ cell tumor (GCT) is the most frequent cancer in young men and is highly curable. Almost 80 % of patients with the disease in an advanced stage achieve a reliable response to cisplatin combination chemotherapy. For relapsing or refractory disease, autologous hematopoietic stem cell transplantation (HSCT) is an effective therapy. Read More

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http://dx.doi.org/10.1007/s10238-016-0425-2DOI Listing
August 2017
34 Reads

The Effect of Testicular Torsion Duration on Testicular Steroidogenesis in the Rat Model.

Urol Int 2016 27;97(3):358-364. Epub 2016 Apr 27.

Department of Urology, Namik Kemal University School of Medicine, Tekirdag, Turkey.

Background: Testicular torsion is an emergency condition in which spermatogenesis may be irreversibly damaged. There have been controversial results about the effect of testicular torsion on steroidogenesis. We aimed at investigating the effect of testicular torsion on steroidogenesis. Read More

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http://dx.doi.org/10.1159/000443969DOI Listing
April 2017
6 Reads
1.151 Impact Factor

Interactive effects of hypoxia, carbon monoxide and acute lung injury on oxygen transport and aerobic capacity.

Respir Physiol Neurobiol 2016 May 1;225:31-7. Epub 2016 Feb 1.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA, USA. Electronic address:

This study determined how breathing hypoxic gas, reducing circulatory capacitance for O2 by breathing CO, and impairing pulmonary gas exchange by acutely injuring the lungs interact to limit cardiopulmonary O2 delivery, O2 extraction and maximal aerobic capacity (VO2max). Five goats ran on a treadmill at VO2max following oleic-acid induced acute lung injury that impaired pulmonary gas exchange, after partial recovery or with no acute lung injury. Goats breathed normoxic or hypoxic inspired gas fractions (FIO2 0. Read More

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http://dx.doi.org/10.1016/j.resp.2016.01.005DOI Listing

Partial Orchiectomy for the Treatment of a Benign Sclerosing Sertoli Cell Tumor: A Report of a Rare Tumor in Association With Testicular Microlithiasis.

Authors:
Adam James Ball

Urol Case Rep 2015 Mar 16;3(2):15-7. Epub 2015 Jan 16.

Gulfstream Urology Associates, PA, 579 NW Lake Whitney Place, Suite 105, Port St. Lucie, FL 34986, USA.

The diagnosis of a testicular sclerosing Sertoli cell tumor is rare. Approximately 17 cases have been previously described in the literature worldwide. We present a case and review the evaluation and surgical management of a sclerosing Sertoli cell tumor presenting in a 26 year-old African-American adult, in association with testicular microlithiasis and oligospermia. Read More

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http://dx.doi.org/10.1016/j.eucr.2014.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714274PMC

The effect of the perfluorocarbon emulsion Oxycyte on platelet count and function in the treatment of decompression sickness in a swine model.

Blood Coagul Fibrinolysis 2016 Sep;27(6):702-10

Operational and Undersea Medicine Directorate, Naval Medical Research Center, Silver Spring, Maryland, USA.

Decompression from elevated ambient pressure is associated with platelet activation and decreased platelet counts. Standard treatment for decompression sickness (DCS) is hyperbaric oxygen therapy. Intravenous perfluorocarbon (PFC) emulsion is a nonrecompressive therapy being examined that improves mortality in animal models of DCS. Read More

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http://dx.doi.org/10.1097/MBC.0000000000000481DOI Listing
September 2016
64 Reads

Selective androgen receptor modulator activity of a steroidal antiandrogen TSAA-291 and its cofactor recruitment profile.

Eur J Pharmacol 2015 Oct 1;765:322-31. Epub 2015 Sep 1.

Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan. Electronic address:

Selective androgen receptor modulators (SARMs) specifically bind to the androgen receptor and exert agonistic or antagonistic effects on target organs. In this study, we investigated the SARM activity of TSAA-291, previously known as a steroidal antiandrogen, in mice because TSAA-291 was found to possess partial androgen receptor agonist activity in reporter assays. In addition, to clarify the mechanism underlying its tissue selectivity, we performed comprehensive cofactor recruitment analysis of androgen receptor using TSAA-291 and dihydrotestosterone (DHT), an endogenous androgen. Read More

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http://dx.doi.org/10.1016/j.ejphar.2015.08.052DOI Listing
October 2015
4 Reads

A unique case of a serous borderline tumor of the paratestis.

Urol Ann 2015 Jul-Sep;7(3):380-2

Department of Radiology, Loyola University Medical Center, 2160 South First Street Ave., Maywood, IL 60153, USA.

Serous borderline tumors of the paratestis are histologically identical to their ovarian counterparts and hypothesized to arise from Mullerian metaplasia of the tunica vaginalis. They are exceedingly rare with many cases probably going clinically unnoticed. We present a case of serous borderline tumor of the paratestis, with, to the best of our knowledge, the first published sonographic and magnetic resonance (MR) images of this entity. Read More

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http://dx.doi.org/10.4103/0974-7796.152042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518381PMC
August 2015
1 Read

Leydig cell hyperplasia in the setting of Klinefelter syndrome.

BMJ Case Rep 2015 Jul 24;2015. Epub 2015 Jul 24.

Tripler Army Medical Center, Tripler, Hawaii, USA.

A man in his 20's with Klinefelter syndrome presented to the urology clinic with a recent history of left-sided orchalgia. Ultrasound evaluation demonstrated multiple small hypoechoic lesions bilaterally, with the largest lesion measured at 5 mm × 6 mm × 8 mm. Testis cancer tumour markers, chest radiographs and abdominal CT imaging were negative. Read More

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http://casereports.bmj.com/content/2015/bcr-2015-209805.full
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http://dx.doi.org/10.1136/bcr-2015-209805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521543PMC

[Bilateral and synchronous testicular teratoma: a case report and literature review].

Cir Cir 2015 Nov-Dec;83(6):527-31. Epub 2015 Jul 9.

Servicio de Patología, Hospital Regional de Zona 1, Instituto Mexicano del Seguro Social, Santiago de Querétaro, Querétaro, México.

Background: Testicular germ-cell carcinoma is the most frequent neoplasm in males aged 15 to 35 years old. It is bilateral in 2% to 3%, and synchronous in 20% to 25% of the cases.

Clinical Case: The case is presented of a 19 year-old male, with abdominal pain. Read More

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http://dx.doi.org/10.1016/j.circir.2015.05.035DOI Listing
September 2016
3 Reads

Male-to-Female Genital Reassignment Surgery: A Retrospective Review of Surgical Technique and Complications in 60 Patients.

J Sex Med 2015 Aug 2;12(8):1837-45. Epub 2015 Jul 2.

Department of Plastic and Reconstructive Surgery, Hospital Clinic, Barcelona, Spain.

Background: Patients with male-to-female gender dysphoria (GD) require multidisciplinary assessment and management. Nowadays, more and more patients decide to undergo genital reassignment surgery (GRS) to have aesthetic and functional external female genitalia. Different techniques of this procedure have been described. Read More

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http://dx.doi.org/10.1111/jsm.12936DOI Listing
August 2015
24 Reads

The role of testis-sparing surgery in children and adolescents with testicular tumors.

Urol Oncol 2016 Feb 17;34(2):76-83. Epub 2015 Jun 17.

Department of Pediatric Urology, Rainbow Babies & Children׳s Hospital/University Hospitals Case Medical Center, Cleveland, OH.

Organ-sparing approaches have been applied to the treatment of a variety of urologic tumors in both the realms of adult and pediatric urology, with the goals of minimizing overtreatment of benign lesions, preserving function, and providing durable cure. The predominance of benign tumors in prepubertal patients and the reliability of both ultrasound and intraoperative frozen sections have resulted in a marked shift toward testis-sparing approaches over the last few decades. The role of testis sparing in the adolescent population is presently unclear, although there have been increasing reports of successful organ-sparing surgery for testis tumors in the adult literature. Read More

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http://dx.doi.org/10.1016/j.urolonc.2015.05.019DOI Listing
February 2016

[Complete androgen insensitivity syndrome].

Srp Arh Celok Lek 2015 Mar-Apr;143(3-4):214-8

Summary Introduction: Androgen insensitivity syndrome (AIS) belongs to disorders of sex development, resulting from complete or partial resistance to the biological actions of androgens in persons who are genetically males (XY) with normally developed testes and age-appropriate for males of serum testosterone concentration.

Case Outline: A 21-year-old female patient was admitted at our Clinic further evaluation and treatment of testicular feminization syndrome, which was diagnosed at the age of 16 years.The patient had never menstruated. Read More

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October 2015
6 Reads

Refinement and partial validation of the UNESP-Botucatu multidimensional composite pain scale for assessing postoperative pain in horses.

BMC Vet Res 2015 Apr 1;11:83. Epub 2015 Apr 1.

School of Veterinary Science, Langford House, Langford, UK.

Background: Quantification of pain plays a vital role in the diagnosis and management of pain in animals. In order to refine and validate an acute pain scale for horses a prospective, randomized, blinded study was conducted. Twenty-four client owned adult horses were recruited and allocated to one of four following groups: anaesthesia only (GA); pre-emptive analgesia and anaesthesia (GAA,); anaesthesia, castration and postoperative analgesia (GC); or pre-emptive analgesia, anaesthesia and castration (GCA). Read More

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http://dx.doi.org/10.1186/s12917-015-0395-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393617PMC
April 2015
20 Reads

Acute scrotal pain and priapism: an early sign of progression in metastatic renal cell carcinoma?

BMJ Case Rep 2015 Feb 18;2015. Epub 2015 Feb 18.

Department of Urology, Bart's Health NHS Trust, London, UK.

A 43 -year-old man was treated with pazopanib for metastatic renal cell carcinoma (RCC) with imaging studies suggesting a partial response to treatment. However, the patient presented numerous times with severe testicular pain and gradually increasing priapism. He underwent an inguinal orchidectomy for symptom control. Read More

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http://dx.doi.org/10.1136/bcr-2014-208228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336893PMC
February 2015

Different types of androgen receptor mutations in patients with complete androgen insensitivity syndrome.

Intractable Rare Dis Res 2015 Feb;4(1):54-9

Department of Urology, Huashan Hospital of Fudan University, Shanghai, China;

Mutations of androgen receptor (AR) are the most frequent cause of 46, XY disorders of sex development and associated with a variety of phenotypes, ranging from phenotypic women (complete androgen insensitivity syndrome (CAIS)) to milder degrees of undervirilization (partial form or PAIS) or men with only infertility (mild form or MAIS). From 2009 to 2012, two young Chinese female individuals with CAIS from two families were referred to our hospital due to primary amenorrhea. Defects in testosterone (T) and dihydrotestosterone (DHT) synthesis were excluded. Read More

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http://dx.doi.org/10.5582/irdr.2014.01035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322596PMC
February 2015
1 Read

Segmental testicular infarction: A case report.

Exp Ther Med 2015 Mar 19;9(3):758-760. Epub 2014 Dec 19.

Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China.

The incidence of segmental testicular infarction is extremely low. The condition usually presents with acute scrotal pain and may be confused clinically and radiologically with a testicular tumor or torsion. To the best of our knowledge, only a few cases have been reported in the English literature. Read More

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http://dx.doi.org/10.3892/etm.2014.2151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316981PMC
March 2015
1 Read

[Testicular nodules of infertile men and contrast enhanced ultrasonography: preliminary study].

Prog Urol 2015 Apr 7;25(5):274-81. Epub 2015 Feb 7.

Service d'andrologie, hôpital Calmette, CHRU de Lille, boulevard du Professeur-Jules-Leclercq, 59037 Lille, France.

Introduction: The incidence of testicular nodules discovered during infertility evaluation is increasing. These nodules are suspicious of malignancy. There is no paraclinical examination which allows histological orientation to these nodules. Read More

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http://dx.doi.org/10.1016/j.purol.2015.01.007DOI Listing
April 2015
1 Read

Conventional Cisplatin-Based Combination Chemotherapy Is Effective in the Treatment of Metastatic Spermatocytic Seminoma with Extensive Rhabdomyosarcomatous Transformation.

Cancer Res Treat 2015 Oct 11;47(4):931-6. Epub 2014 Sep 11.

Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

A 52-year-old man was presented with a huge left testicular mass and palpable cervical lymphadenopathy with retroperitoneal lymph node enlargement on an abdominal computed tomography. A left radical orchiectomy and an ultrasound-guided neck node biopsy were performed. A pathological examination revealed spermatocytic seminoma with extensive rhabdomyosarcomatous transformation, a condition known to be highly resistant to platinum-based chemotherapy. Read More

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http://dx.doi.org/10.4143/crt.2014.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614201PMC
October 2015
2 Reads

Testis sparing surgery in the treatment of bilateral testicular germ cell tumors and solitary testicle tumors: A single institution experience.

J Surg Oncol 2015 Feb 5;111(2):226-30. Epub 2014 Sep 5.

Clinic of Urology, Clinical Center of Serbia, Belgrade, Serbia; School of Medicine, University of Belgrade, Belgrade, Serbia.

Background And Objective: To assess the oncologic and functional outcomes of testicular sparing surgery (TSS) based on a single institution experience.

Methods: Forty-one patients with bilateral and 3 patients with solitary testicle tumors were referred to our institution. The inclusion criteria for TSS were normal serum testosterone levels, and tumor size (<2 cm). Read More

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http://dx.doi.org/10.1002/jso.23777DOI Listing
February 2015
16 Reads