2,703 results match your criteria Orbivirus


Characterization of Novel Reoviruses [Wad Medani virus (Orbivirus) and Kundal (Coltivirus)] collected from ticks in India during CCHF surveillance.

J Virol 2019 Apr 10. Epub 2019 Apr 10.

ICMR-National Institute of Virology, Pune, India

In 2011, ticks were collected from livestock following an outbreak of Crimean Congo Hemorrhagic fever (CCHF) in Gujarat state, India. CCHF-negative tick pools were passaged for virus isolation, and two virus isolates were obtained, designated Karyana virus (KARYV) and Kundal virus (KUNDV) respectively. Traditional RT-PCR identification of known viruses was unsuccessful, but a next-generation sequencing approach identified KARYV and KUNDV as viruses in the family, , and genera, respectively. Read More

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http://dx.doi.org/10.1128/JVI.00106-19DOI Listing
April 2019
1 Read

Molecular typing of Bluetongue virus using the nCounter analysis system platform.

J Virol Methods 2019 Apr 2;269:64-69. Epub 2019 Apr 2.

OIE Reference Laboratory for Bluetongue, Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, Italy; National Reference Center for Whole Genome Sequencing of Microbial Pathogens: Database and Bioinformatic Analysis, Istituto Zooprofilattico Sperimentale dell'Abruzzo e Molise, Teramo, Italy. Electronic address:

Bluetongue virus (BTV) is a segmented double-stranded RNA virus, existing in multiple serotypes, belonging to the genus Orbivirus of the family Reoviridae. BTV causes Bluetongue (BT), a major OIE-listed disease of ruminants. Identification of BTV serotype is accomplished using multiple typing assays and tends to be executed based on the known epidemiological situation within a given country. Read More

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http://dx.doi.org/10.1016/j.jviromet.2019.04.002DOI Listing
April 2019
1 Read

Genome Sequences of a Novel Strain of Big Cypress Orbivirus Isolated from a Dead Florida White-Tailed Deer (Odocoileus virginianus).

Microbiol Resour Announc 2019 Mar 14;8(11). Epub 2019 Mar 14.

Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA

Here, we report the coding sequences of Big Cypress orbivirus isolated from a dead white-tailed deer () from Florida in 2017. To our knowledge, this is the first detection of Big Cypress orbivirus in a vertebrate host. Read More

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http://dx.doi.org/10.1128/MRA.01717-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424215PMC

Detection of Epizootic Hemorrhagic Disease Virus Serotype 1, Israel.

Emerg Infect Dis 2019 Apr;25(4):825-827

During September 2016-February 2017, we detected epizootic hemorrhagic disease virus (EHDV) in ruminants in Israel. BLAST and phylogenetic analyses of segment 2 in 6 EHDVs isolated from field samples indicated a close relationship to the EHDV serotype 1 strain in Nigeria. Affected cattle had mostly mild or asymptomatic disease. Read More

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http://dx.doi.org/10.3201/eid2504.180149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433031PMC
April 2019
6.751 Impact Factor

Epizootic Hemorrhagic Disease in White-Tailed Deer, Canada.

Emerg Infect Dis 2019 Apr;25(4):832-834

Epizootic hemorrhagic disease affects wild and domestic ruminants and has recently spread northward within the United States. In September 2017, we detected epizootic hemorrhagic disease virus in wild white-tailed deer, Odocoileus virginianus, in east-central Canada. Culicoides spp. Read More

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http://dx.doi.org/10.3201/eid2504.180743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433007PMC

Bluetongue virus vaccine: conventional to modern approach.

Acta Virol 2019;63(1):3-18

Bluetongue (BT) is an economically important, infectious and non-contagious disease of ruminant animals. BT disease is caused by bluetongue virus (BTV) of the genus Orbivirus (the family Reoviridae). BTV is transmitted by certain species of biting midges of the genus Culicoides. Read More

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http://dx.doi.org/10.4149/av_2019_109DOI Listing
January 2019
1 Read

Evaluation of 2012 US EHDV-2 outbreak isolates for genetic determinants of cattle infection.

J Gen Virol 2019 Apr 14;100(4):556-567. Epub 2019 Mar 14.

1​United States Department of Agriculture, Agricultural Research Service, Arthropod-borne Animal Diseases Research Unit, 1515 College Avenue, Manhattan, KS 66502, USA.

Following a summer of severe drought and abnormally high temperatures, a major outbreak of EHDV occurred during 2012 in the USA. Although EHDV-1, -2 and -6 were isolated, EHDV-2 was the predominant virus serotype detected during the outbreak. In addition to large losses of white-tailed deer, the Midwest and northern Plains saw a significant amount of clinical disease in cattle. Read More

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http://dx.doi.org/10.1099/jgv.0.001221DOI Listing

Diagnosing bluetongue virus in domestic ruminants: current perspectives.

Vet Med (Auckl) 2019 14;10:17-27. Epub 2019 Feb 14.

Centro de Investigación en Sanidad Animal (CISA-INIA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Valdeolmos, Madrid, Spain,

This review provides an overview of current and potential new diagnostic techniques against bluetongue virus (BTV), an transmitted by arthropods that affects ruminants. Bluetongue is a disease currently notifiable to the World Organization for Animal Health (OIE), causing great economic losses due to decreased trade associated with bluetongue outbreaks and high mortality and morbidity. BTV cross-reacts with many antigenically related viruses including viruses that causes African Horse sickness and epizootic haemorrhagic disease of deer. Read More

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http://dx.doi.org/10.2147/VMRR.S163804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385761PMC
February 2019
1 Read

Discovery and Characterization of Bukakata orbivirus (), a Novel Virus from a Ugandan Bat.

Viruses 2019 Mar 2;11(3). Epub 2019 Mar 2.

Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA.

While serological and virological evidence documents the exposure of bats to medically-important arboviruses, their role as reservoirs or amplifying hosts is less well-characterized. We describe a novel orbivirus () isolated from an Egyptian fruit bat () trapped in 2013 in Uganda and named Bukakata orbivirus. This is the fifth orbivirus isolated from a bat, however genetic information had previously only been available for one bat-associated orbivirus. Read More

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http://dx.doi.org/10.3390/v11030209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466370PMC
March 2019
1 Read
3.279 Impact Factor

Evidence of bluetongue virus circulation in farmed and free-ranging cervids from the Republic of Korea: A retrospective cross-sectional study.

Vet Microbiol 2019 Mar 5;230:145-149. Epub 2019 Feb 5.

Department of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Academy-ro 119, Yeonsu-gu, Incheon, 22012, Republic of Korea; Emerging & Exotic Diseases Research Laboratory, Foreign Animal Diseases Division, National Veterinary Research and Quarantine Service, Anyang-ro 175, Manan-gu, Anyang-si, Gyeonggi-do, 14089, Republic of Korea. Electronic address:

Bluetongue, which is caused by bluetongue virus (BTV), is a vector-borne viral disease that affects wild and domestic ruminants. Trade restrictions can have a devastating impact in areas where BTV is endemic, regardless of the incidence of clinical disease. Currently, little is known about the prevalence of BTV infection in the Republic of Korea (ROK), and limited data on the BTV situation in the ROK are available. Read More

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http://dx.doi.org/10.1016/j.vetmic.2019.02.009DOI Listing
March 2019
3 Reads

Complete Genome Sequence of Mobuck Virus Isolated from a Florida White-Tailed Deer (Odocoileus virginianus).

Microbiol Resour Announc 2019 Jan 17;8(3). Epub 2019 Jan 17.

Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.

Here, we report the complete genome sequence of mobuck virus isolated from a Florida white-tailed deer (Odocoileus virginianus) in 2017. This is the second report of mobuck virus in the United States and expands the known geographic range of this novel orbivirus into Florida. Read More

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http://dx.doi.org/10.1128/MRA.01324-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346154PMC
January 2019

Identification and characterization of epizootic hemorrhagic disease virus serotype 6 in cattle co-infected with bluetongue virus in Trinidad, West Indies.

Vet Microbiol 2019 Feb 11;229:1-6. Epub 2018 Dec 11.

School of Veterinary Medicine, Faculty of Medical Sciences, The University of theWest Indies, St. Augustine, Trinidad, West Indies.

Epizootic hemorrhagic disease virus (EHDV) is an economically important virus that can cause severe clinical disease in deer and to a lesser extent cattle. This study set out to determine and characterize which EHDV serotypes were circulating in Trinidad. Serum and whole blood samples were collected monthly for six months from a cohort of cattle imported to Trinidad from the USA. Read More

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http://dx.doi.org/10.1016/j.vetmic.2018.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340808PMC
February 2019
3 Reads

Quantitative RT-PCR assays for identification and typing of the Equine encephalosis virus.

Braz J Microbiol 2019 Jan 10;50(1):287-296. Epub 2018 Dec 10.

The Pirbright Institute, Ash Road, Pirbright, GU24 0NF, UK.

Equine encephalosis (EE) is an acute, arthropod-borne, noncontagious, febrile disease of equids. The clinical signs of EE are similar to milder forms of African horse sickness (AHS) and the two diseases can be easily confused. The Equine encephalosis virus (EEV) is a distinct virus species within the genus Orbivirus, family Reoviridae, with ten linear segments of dsRNA genome. Read More

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http://dx.doi.org/10.1007/s42770-018-0034-1DOI Listing
January 2019
2 Reads

Skunk River virus, a novel orbivirus isolated from Aedes trivittatus in the United States.

J Gen Virol 2019 Feb 11;100(2):295-300. Epub 2019 Jan 11.

1​Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA.

The genomic organization and in vitro host range of a novel mosquito-associated orbivirus, designated Skunk River virus, is described. The virus was isolated from Aedes trivittatus collected in Iowa in the United States. Three recognized viruses were also recovered: Culex flavivirus (family Flaviviridae), Houston virus (family Mesoniviridae) and Umatilla virus (family Reoviridae). Read More

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http://www.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/jgv.0.001219DOI Listing
February 2019
11 Reads

Evidence of bluetongue and Epizootic Haemorrhagic disease circulation on the island of Mayotte.

Acta Trop 2019 Mar 24;191:24-28. Epub 2018 Dec 24.

ASTRE, Univ Montpellier, CIRAD, INRA, Montpellier, France; CIRAD, UMR ASTRE, Sainte Clotilde, La Réunion, France.

A cross-sectional study was conducted to explore the epidemiological situation in Mayotte regarding two orbiviruses: Bluetongue virus (BTV) and Epizootic Haemorrhagic Disease virus (EHDV). In all, 385 individual asymptomatic cattle were blood-sampled (one EDTA and one serum tube per animal) between February and June 2016. Antibody (ELISA) and genome prevalence (PCR) was assessed. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.12.037DOI Listing
March 2019
1 Read

Reassortment of bluetongue virus vaccine serotypes in cattle.

J S Afr Vet Assoc 2018 Dec 5;89(0):e1-e7. Epub 2018 Dec 5.

Department of Veterinary Tropical Diseases, University of Pretoria.

Bluetongue is primarily a disease of sheep in South Africa, while cattle and goats are mostly subclinically infected. The viraemia of bluetongue virus in cattle lasts much longer than in sheep and the role of cattle in the epidemiology of bluetongue in South Africa is poorly understood. Bluetongue virus has a segmented double-stranded ribonucleic acid genome and reassortment of genomes is a common feature. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295955PMC
http://dx.doi.org/10.4102/jsava.v89i0.1649DOI Listing
December 2018

The Interaction of Bluetongue Virus VP6 and Genomic RNA Is Essential for Genome Packaging.

J Virol 2019 Mar 19;93(5). Epub 2019 Feb 19.

Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

The genomes of the , including the animal pathogen bluetongue virus (BTV), are multisegmented double-stranded RNA (dsRNA). During replication, single-stranded (ss) positive-sense RNA segments are packaged into the assembling virus capsid, triggering genomic dsRNA synthesis. However, exactly how this packaging event occurs is not clear. Read More

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http://jvi.asm.org/lookup/doi/10.1128/JVI.02023-18
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http://dx.doi.org/10.1128/JVI.02023-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384066PMC
March 2019
4 Reads

Bovine viral diarrhea in captive Rocky Mountain bighorn sheep associated with administration of a contaminated modified-live bluetongue virus vaccine.

J Vet Diagn Invest 2019 Jan 12;31(1):107-112. Epub 2018 Dec 12.

Colorado Parks and Wildlife, Fort Collins, CO (Fox, Wolfe).

In late summer 2017, we observed acute, fatal cases of bovine viral diarrhea in captive Rocky Mountain bighorn sheep ( Ovis canadensis canadensis) in Colorado following use of a contaminated modified-live bluetongue virus vaccine. Following vaccination, at least 14 of 28 (50%) vaccinated bighorn sheep developed hemorrhagic diarrhea, and 6 of 28 (21%) vaccinated bighorn sheep died. Autopsy findings were predominantly necroulcerative-to-necrohemorrhagic gastrointestinal lesions. Read More

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http://dx.doi.org/10.1177/1040638718814583DOI Listing
January 2019

Isolation and Genome Phylogenetic Analysis of Arthropod-Borne Viruses, Including Akabane Virus, from Mosquitoes Collected in Hunan Province, China.

Vector Borne Zoonotic Dis 2019 01 11;19(1):62-72. Epub 2018 Dec 11.

1 State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

This study investigated the abundance of mosquitoes and circulation of mosquito-borne arboviruses from 16 villages in 8 cities of Hunan Province, China, in July-August of 2010 and in August of 2011. In total, 16,076 mosquitoes consisting of seven species from four genera were collected by ultraviolet-light trap. Culex quinquefasciatus was the most common species, accounting for 50. Read More

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https://www.liebertpub.com/doi/10.1089/vbz.2018.2267
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http://dx.doi.org/10.1089/vbz.2018.2267DOI Listing
January 2019
19 Reads

Amino acid starvation accelerates replication of Ibaraki virus.

Virus Res 2019 01 29;260:94-101. Epub 2018 Nov 29.

Laboratory of Veterinary Hygiene, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1, Yoshida, Yamaguchi, 753-8515, Japan. Electronic address:

Ibaraki virus (IBAV) is a strain of epizootic hemorrhagic disease virus 2 that belongs to the genus Orbivirus of the family Reoviridae. IBAV replication is suppressed by the inhibition of autophagy, and since mechanistic target of rapamycin complex 1 (mTORC1) is a key regulator of autophagy, we examined if mTORC1 inhibition by amino acid starvation or mTOR inhibitors (Torin 1 and rapamycin) affects IBAV replication. We found that IBAV replication is significantly enhanced after amino acid starvation of host cells, but not after treatment with mTOR inhibitors, during early stages of viral infection (0-1 hpi). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01681702173092
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http://dx.doi.org/10.1016/j.virusres.2018.10.008DOI Listing
January 2019
12 Reads

Multiple bluetongue virus serotypes causing death in Brazilian dwarf brocket deer (Mazama nana) in Brazil, 2015-2016.

Vet Microbiol 2018 Dec 26;227:143-147. Epub 2018 Oct 26.

Centro de Ciências Agroveterinárias, Universidade do Estado de Santa Catarina, Av. Luiz de Camões, 2090, Conta Dinheiro, Lages, Santa Catarina, CEP 88.520-000, Brazil.

Bela Vista Biological Sanctuary (RBV) is a protected area of Itaipu Binacional, a hydroelectric power company located on the border of Brazil and Paraguay. A captive population of Brazilian dwarf brocket deer (Mazama nana, Cervidae, Artiodactyla) is maintained for conservation purposes. Despite the reproductive success of the animals, outbreaks of a fatal hemorrhagic disease have been registered over the years, compromising conservation efforts. Read More

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http://dx.doi.org/10.1016/j.vetmic.2018.10.018DOI Listing
December 2018
2 Reads

Exploiting serological data to understand the epidemiology of bluetongue virus serotypes circulating in Libya.

Vet Med Sci 2019 02 23;5(1):79-86. Epub 2018 Nov 23.

Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya.

The epidemiological patterns of Bluetongue (BT) in North Africa and Mediterranean Basin (MB) dramatically changed by emergence of subsequent episodes of novel bluetongue virus (BTV) serotypes with highly pathogenic indexes and socio-economic impacts. The objective of the study was to investigate the sero-prevalence and serotype distribution of BTV in Libya. During 2015-2016, a total of 826 serum samples were collected from domestic ruminants in Libya. Read More

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http://dx.doi.org/10.1002/vms3.136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376171PMC
February 2019
2 Reads

Chuzan Virus in Yaks, Qinghai-Tibetan Plateau, China.

Emerg Infect Dis 2018 12;24(12):2371-2373

We detected Chuzan virus (CHUV) in domestic yaks from the Qinghai-Tibetan Plateau, western China, indicating CHUV probably has been transmitted to yaks in recent years. Awareness for CHUV surveillance and transmission and livestock health management in these special regions should be raised to avoid outbreaks and animal loss. Read More

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http://dx.doi.org/10.3201/eid2412.171414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256394PMC
December 2018
17 Reads
6.751 Impact Factor

The first report on serotyping of bluetongue virus in small ruminants of Khyber Pakhtunkhwa province, Pakistan.

Trop Anim Health Prod 2019 May 7;51(4):977-982. Epub 2018 Nov 7.

University College of Veterinary and Animal Sciences, Islamia University of Bahawalpur Pakistan, Bahawalpur, Pakistan.

Bluetongue virus (BTV), a member of Orbivirus genus (family Reoviridae), is a non-contagious infection of domestic and wild ruminants. The current study was designed to detect various serotypes of BTV in small ruminants of Khyber Pakhtunkhwa (KPK) province of Pakistan, along with their effects on hemato-biochemical parameters. A total of 408 serum samples in four districts (Mansehra, Abbottabad, Swabi, and Kohat) of KPK from small ruminants were screened based on competitive ELISA (cELISA). Read More

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http://dx.doi.org/10.1007/s11250-018-1739-8DOI Listing
May 2019
3 Reads

Evaluation of an IGM-specific ELISA for early detection of bluetongue virus infections in domestic ruminants sera.

Transbound Emerg Dis 2019 Jan 23;66(1):537-545. Epub 2018 Nov 23.

Laboratoire de Santé Animale d'Alfort, Université Paris Est, ANSES, ENVA, INRA, UMR 1161 VIROLOGIE, Maisons-Alfort, France.

Competitive-ELISA (c-ELISA) is the most widely used serological test for the detection of Bluetongue virus (BTV) viral protein 7 (VP7) antibodies (Ab). However, these BTV c-ELISAs cannot to distinguish between IgG and IgM. IgM Ab are generated shortly after the primary immune response against an infectious agent, indicating a recent infection or exposure to antigens, such as after vaccination. Read More

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http://doi.wiley.com/10.1111/tbed.13060
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http://dx.doi.org/10.1111/tbed.13060DOI Listing
January 2019
8 Reads

Beta-propiolactone inactivated bivalent bluetongue virus vaccine containing Montanide ISA-71VG adjuvant induces long-term immune response in sheep against serotypes 4 and 16 even after 3 years of controlled vaccine storage.

Vet Microbiol 2018 Nov 10;226:23-30. Epub 2018 Oct 10.

Microbial Collection Laboratory, Research Institute for Biological Safety Problems, Gvardeiskiy, Kazakhstan.

In this study, we developed and evaluated the beta-propiolactone inactivated bivalent bluetongue virus (BTV) serotypes 4 and 16 vaccine delivered with Montanide™ ISA-71VG adjuvant. The safety, stability and immunological profile of the fresh and after three years of long-term storage of the vaccine formulation was analyzed. We observed after long-term storage that the vaccine emulsion was stable as indicated by unchanged pH and viscosity. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03781135183065
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http://dx.doi.org/10.1016/j.vetmic.2018.10.003DOI Listing
November 2018
8 Reads

Safety and immunogenicity of plant-produced African horse sickness virus-like particles in horses.

Vet Res 2018 Oct 11;49(1):105. Epub 2018 Oct 11.

Biopharming Research Unit, Department of Molecular and Cell Biology, University of Cape Town, Rondebosch, Cape Town, 7701, South Africa.

African horse sickness (AHS) is caused by multiple serotypes of the dsRNA AHSV and is a major scourge of domestic equids in Africa. While there are well established commercial live attenuated vaccines produced in South Africa, risks associated with these have encouraged attempts to develop new and safer recombinant vaccines. Previously, we reported on the immunogenicity of a plant-produced AHS serotype 5 virus-like particle (VLP) vaccine, which stimulated high titres of AHS serotype 5-specific neutralizing antibodies in guinea pigs. Read More

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https://veterinaryresearch.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s13567-018-0600-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389048PMC
October 2018
3 Reads

Characterization of cathepsin C from orange-spotted grouper, Epinephelus coioides involved in SGIV infection.

Fish Shellfish Immunol 2019 Jan 9;84:423-433. Epub 2018 Oct 9.

College of Marine Sciences, South China Agricultural University, Guangzhou, 510642, China; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China. Electronic address:

The lysosomal cysteine protease cathepsin C plays a pivotal role in regulation of inflammatory and immune responses. However, the function of fish cathepsin C in virus replication remains largely unknown. In this study, cathepsin C gene (Ec-CC) was cloned and characterized from orange-spotted grouper, Epinephelus coioides. Read More

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http://dx.doi.org/10.1016/j.fsi.2018.10.027DOI Listing
January 2019
2 Reads

Effectiveness and cost-benefit study to encourage herd owners in a cost sharing vaccination programme against bluetongue serotype-8 in Belgium.

Transbound Emerg Dis 2019 Jan 26;66(1):400-411. Epub 2018 Oct 26.

Epidemiology and Public Health, Veterinary Epidemiology, Brussels, Belgium.

Bluetongue (BT) is a ruminant viral infectious disease transmitted by Culicoides spp. midges. In 2006, when bluetongue virus serotype 8 (BTV-8) appeared for the first time in Northern Europe, it rapidly spread and infected a large proportion of animals. Read More

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http://doi.wiley.com/10.1111/tbed.13034
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http://dx.doi.org/10.1111/tbed.13034DOI Listing
January 2019
29 Reads

Seroprevalence of Bluetongue virus in small and large ruminants in Punjab province, Pakistan.

Acta Trop 2019 Jan 24;189:22-29. Epub 2018 Sep 24.

University of Veterinary and Animal Sciences, Lahore 54600, Pakistan. Electronic address:

Bluetongue (BT) is a vector-borne disease of immense economic importance for small and large ruminants. Despite frequent disease reports from neighboring countries, a little is known about current disease status and prevalent serotypes in Pakistan. We screened a total of 1312 healthy animals for group-specific antibodies and serotype-specific genome for BT virus through competitive ELISA and real-time PCR, respectively. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0001706X183083
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http://dx.doi.org/10.1016/j.actatropica.2018.09.020DOI Listing
January 2019
17 Reads
2.270 Impact Factor

Longitudinal monitoring of Culicoides in Belgium between 2007 and 2011: local variation in population dynamics parameters warrant cautious use of monitoring data.

Parasit Vectors 2018 Sep 17;11(1):512. Epub 2018 Sep 17.

Enzootic, vector-borne and bee diseases, Sciensano, Brussels, Belgium.

Background: Several European countries suffered important economic losses during the past decade due to the emergence of bluetongue and Schmallenberg viruses. Both are viruses of veterinary importance and are spread by Culicoides spp. This triggered many European countries to start Culicoides population monitoring. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3082-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142705PMC
September 2018
24 Reads

Cluster analysis of hemorrhagic disease in Missouri's white-tailed deer population: 1980-2013.

BMC Ecol 2018 09 14;18(1):35. Epub 2018 Sep 14.

Department of Math and Statistics, University of Missouri-Kansas City, 5120 Rockhill Road, Kansas City, MO, 64110, USA.

Background: Outbreaks of deer hemorrhagic disease (HD) have been documented in the USA for many decades. In the year 2012, there was a severe HD outbreak in Missouri with mortalities reaching approximately 6.9 per thousand. Read More

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http://dx.doi.org/10.1186/s12898-018-0188-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137738PMC
September 2018
4 Reads

Molecular and serological surveillance of African horse sickness virus in eastern and central Saudi Arabia.

Rev Sci Tech 2017 Dec;36(3):889-898

African horse sickness virus (AHSV) is one of the most devastating viral diseases of the family Equidae. Infection with AHSV threatens not only the Saudi equine industry but also the equine industry worldwide. This is due to the high morbidity and mortality rates among the infected population of up to 100%. Read More

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http://dx.doi.org/10.20506/rst.36.3.2722DOI Listing
December 2017
4 Reads

The role of climate change in a developing threat: the case of bluetongue in Europe.

Rev Sci Tech 2017 Aug;36(2):467-478

There is a solid theoretical basis for expecting climate change to have a considerable effect on the infectious diseases of humans, animals and plants. Vector-borne diseases are the most likely to be affected. It is, however, rare to observe such impacts, as diseases are also influenced by many other drivers, some of which may have stronger effects over shorter time scales than climate change. Read More

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http://dx.doi.org/10.20506/rst.36.2.2667DOI Listing
August 2017
1 Read

The genome of the biting midge Culicoides sonorensis and gene expression analyses of vector competence for bluetongue virus.

BMC Genomics 2018 Aug 22;19(1):624. Epub 2018 Aug 22.

The Pirbright Institute, Ash Road, Woking, Surrey, GU24 0NF, UK.

Background: The new genomic technologies have provided novel insights into the genetics of interactions between vectors, viruses and hosts, which are leading to advances in the control of arboviruses of medical importance. However, the development of tools and resources available for vectors of non-zoonotic arboviruses remains neglected. Biting midges of the genus Culicoides transmit some of the most important arboviruses of wildlife and livestock worldwide, with a global impact on economic productivity, health and welfare. Read More

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https://bmcgenomics.biomedcentral.com/articles/10.1186/s1286
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http://dx.doi.org/10.1186/s12864-018-5014-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106943PMC
August 2018
4 Reads

Sheep breed and shearing influences attraction and blood-feeding behaviour of Culicoides (Diptera: Ceratopogonidae) on a UK farm.

Parasit Vectors 2018 Aug 20;11(1):473. Epub 2018 Aug 20.

The Pirbright Institute, Pirbright, Surrey, UK.

Background: Culicoides biting midges (Diptera: Ceratopogonidae) are responsible for the biological transmission of arboviruses of international importance between ruminant livestock. These arboviruses include bluetongue virus (BTV) and Schmallenberg virus (SBV), which have emerged in unprecedented outbreaks in northern Europe. The impact of breed and shearing of sheep on Culicoides: host contact rates has not been investigated in detail and has the potential to influence arbovirus transmission and control measures employed to limit spread. Read More

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http://dx.doi.org/10.1186/s13071-018-3003-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102838PMC
August 2018
22 Reads

Culicoides species composition and abundance on Irish cattle farms: implications for arboviral disease transmission.

Parasit Vectors 2018 Aug 17;11(1):472. Epub 2018 Aug 17.

The Pirbright Institute, Ash Rd., Pirbright, Woking, Surrey, GU24 0NF, UK.

Background: Following the emergence of Schmallenberg virus (SBV) in Ireland in 2012, a sentinel herd surveillance program was established in the south of Ireland with the primary aim of investigating the species composition and abundance of Culicoides on livestock farms in the region.

Methods: Ultraviolet-light trapping for Culicoides was carried out on 10 sentinel farms. Each site was sampled fortnightly over 16 weeks (21st July to 5th November 2014). Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3010-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098625PMC
August 2018
14 Reads

Vector competence of pre-alpine Culicoides (Diptera: Ceratopogonidae) for bluetongue virus serotypes 1, 4 and 8.

Parasit Vectors 2018 Aug 13;11(1):466. Epub 2018 Aug 13.

National Centre for Vector Entomology, Institute of Parasitology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland.

Background: Bluetongue disease, caused by bluetongue virus serotype 8 (BTV-8), appeared for the first time in the northern part of Europe in 2006, and subsequently rapidly spread causing severe economic losses to the farming industry. The implicated vectors of BTV in Europe are Culicoides species within the subgenus Avaritia (C. chiopterus, C. Read More

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http://dx.doi.org/10.1186/s13071-018-3050-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090685PMC

Colostral transmission of BTV-8 antibodies from dairy cows six years after vaccination.

Vaccine 2018 09 9;36(39):5807-5810. Epub 2018 Aug 9.

Department of Livestock Sciences, Research Institute of Organic Agriculture (FiBL), Ackerstrasse 113, Postbox 219, 5070 Frick, Switzerland. Electronic address:

Bluetongue virus (BTV) antibodies were analysed in 27 Swiss calves born in 2016 at the age of 16-19 days using competitive enzyme-linked-immunosorbent-assay (cELISA) and virus neutralization test (VNT) (animal trial permission number: 75684). Obligatory documentation proved that 15 of 27 dams were BTV-8 vaccinated once or three times in 2008-2010. The offsprings of the non-vaccinated dams were seronegative. Read More

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http://dx.doi.org/10.1016/j.vaccine.2018.08.015DOI Listing
September 2018
1 Read

Assessment of reproducibility of a VP7 Blocking ELISA diagnostic test for African horse sickness.

Transbound Emerg Dis 2019 Jan 2;66(1):83-90. Epub 2018 Aug 2.

The Pirbright Institute, Pirbright, UK.

The laboratory diagnosis of African horse sickness (AHS) is important for: (a) demonstrating freedom from infection in a population, animals or products for trade (b) assessing the efficiency of eradication policies; (c) laboratory confirmation of clinical diagnosis; (d) estimating the prevalence of AHS infection; and (e) assessing postvaccination immune status of individual animals or populations. Although serological techniques play a secondary role in the confirmation of clinical cases, their use is very important for all the other purposes due to their high throughput, ease of use and good cost-benefit ratio. The main objective of this study was to support the validation of AHS VP7 Blocking ELISA up to the Stage 3 of the World Animal Health Organization (OIE) assay validation pathway. Read More

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http://doi.wiley.com/10.1111/tbed.12968
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http://dx.doi.org/10.1111/tbed.12968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378617PMC
January 2019
11 Reads

Full genome sequence of a Sathuvachari virus strain isolated in the southwestern-most archipelago of Japan.

Virus Genes 2018 Oct 1;54(5):729-732. Epub 2018 Aug 1.

Kyushu Research Station, National Institute of Animal Health, NARO, 2702, Chuzan, Kagoshima, Kagoshima, Japan.

Two virus strains, tentatively designated as ON-6/P/05 and ON-7/E/05, were isolated from blood samples of healthy cattle in the Yaeyama Islands, located in the southwestern-most region of Japan, in 2005. Ultrastructural observations of infected baby hamster (BHK-21) cells revealed that the viruses had features consistent with those of orbivirus. As with other orbiviruses, the viral genome consists of 10 double-stranded RNA segments. Read More

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http://dx.doi.org/10.1007/s11262-018-1592-xDOI Listing
October 2018
18 Reads

Sero-epidemioloical survey on African horse sickness virus among horses in Khartoum State, Central Sudan.

BMC Vet Res 2018 Aug 1;14(1):230. Epub 2018 Aug 1.

Molecular Biology Laboratory (MBL), Department of Clinical Medicine, Faculty of Veterinary Medicine, University of Khartoum, P.O. Box 32, Khartoum North, Sudan.

Background: African horse sickness virus (AHSV) is an infectious non contagious insect-transmitted double-stranded (ds) RNA orbivirus of the family Reoviridae. AHSV causes an often fatal hemorrhagic infection with high mortality among selected breeds of Arabian horses. This study was conducted to avail some information with regard to the prevalence and associated risk factors of AHSV among ecotype breeds of horses in central Sudan. Read More

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https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
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http://dx.doi.org/10.1186/s12917-018-1554-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090883PMC
August 2018
5 Reads

Host use patterns of Culicoides spp. biting midges at a big game preserve in Florida, U.S.A., and implications for the transmission of orbiviruses.

Med Vet Entomol 2019 03 31;33(1):110-120. Epub 2018 Jul 31.

Department of Entomology and Nematology, Florida Medical Entomology Laboratory, University of Florida, Vero Beach, FL, U.S.A.

Culicoides spp. biting midges (Diptera: Ceratopogonidae) are vectors of pathogens that have a significant economic impact on the livestock industry. White-tailed deer (Odocoileus virginianus), a farmed species in the U. Read More

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http://dx.doi.org/10.1111/mve.12331DOI Listing
March 2019
1 Read

Comparative Neuropathology of Major Indian Bluetongue Virus Serotypes in a Neonatal BALB/c Mouse Model.

J Comp Pathol 2018 Jul 3;162:18-28. Epub 2018 Jul 3.

School of Veterinary Medicine and Science, The University of Nottingham, UK.

Bluetongue virus (BTV) is neurotropic in nature, especially in ruminant fetuses and in-utero infection results in abortion and congenital brain malformations. The aim of the present study was to compare the neuropathogenicity of major Indian BTV serotypes 1, 2, 10, 16 and 23 by gross and histopathological lesions and virus distribution in experimentally infected neonatal BALB/c mice. Each BTV serotype (20 μl of inoculum containing 1 × 10 tissue culture infectious dose [TCID]/ml of virus) was inoculated intracerebrally into 3-day-old mice, while a control group was inoculated with mock-infected cell culture medium. Read More

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http://dx.doi.org/10.1016/j.jcpa.2018.06.001DOI Listing
July 2018
12 Reads

Seroprevalence of bluetongue and presence of viral antigen and type-specific neutralizing antibodies in goats in Tripura, a state at Indo-Bangladesh border of northeastern India.

Trop Anim Health Prod 2019 Jan 17;51(1):261-265. Epub 2018 Jul 17.

Division of Virology, Indian Veterinary Research Institute, Mukteswar, Kumaon, Uttarakhand, 263138, India.

Bluetongue (BT) is a notifiable multiple species transboundary viral disease of domestic and wild ruminants. Though the disease is enzootic in India, little is known of the disease burden and prevalent serotypes in Tripura, a hilly state of northeastern India sharing a vast porous border with Bangladesh. A surveillance study was conducted to understand the disease burden in goats in Tripura. Read More

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http://dx.doi.org/10.1007/s11250-018-1672-xDOI Listing
January 2019
2 Reads

Assessment of cross-protection induced by a bluetongue virus (BTV) serotype 8 vaccine towards other BTV serotypes in experimental conditions.

Vet Res 2018 07 16;49(1):63. Epub 2018 Jul 16.

Faculty of Veterinary Medicine, Research Unit in Epidemiology and Risk Analysis Applied to Veterinary Sciences (UREAR-ULg), Fundamental and Applied Research for Animal and Health (FARAH) Center, University of Liege, Liege, Belgium.

Bluetongue disease is caused by bluetongue virus (BTV) and BTV serotype 8 (BTV8) caused great economic damage in Europe during the last decade. From 1998 to 2007, in addition to BTV8, Europe had to face the emergence of BTV1, 2, 4, 9, and 16, spreading in countries where the virus has never been detected before. These unprecedented outbreaks trigger the need to evaluate and compare the clinical, virological and serological features of the European BTV serotypes in the local epidemiological context. Read More

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http://dx.doi.org/10.1186/s13567-018-0556-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048908PMC
July 2018
9 Reads

Prevalence and risk factors for bluetongue in the State of São Paulo, Brazil.

Vet Med Sci 2018 11 2;4(4):280-287. Epub 2018 Jul 2.

Laboratory of Bovine Viruses, Center for Animal Health Research and Development, Biological Institute, Sao Paulo, SP, Brazil.

Bluetongue (BT), caused by Bluetongue virus (BTV), is a disease that affects ruminants such as cattle, sheep, goats and deer. BTV is transmitted by female midges of the genus Culicoides. In Brazil, information on the prevalence of BTV in cattle is limited, so the objective of this work was to identify BTV serotypes in cattle. Read More

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http://dx.doi.org/10.1002/vms3.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236132PMC
November 2018
7 Reads

Identification and characterization of novel mosquito-borne (Kammavanpettai virus) and tick-borne (Wad Medani) reoviruses isolated in India.

J Gen Virol 2018 Aug 25;99(8):991-1000. Epub 2018 Jun 25.

1​Maximum Containment Laboratory, National Institute of Virology, Pune, Maharashtra, India.

In 1954, a virus named Wad Medani virus (WMV) was isolated from Hyalomma marginatum ticks from Maharashtra State, India. In 1963, another virus was isolated from Sturnia pagodarum birds in Tamil Nadu, India, and named Kammavanpettai virus (KVPTV) based on the site of its isolation. Originally these virus isolates could not be identified with conventional methods. Read More

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http://dx.doi.org/10.1099/jgv.0.001102DOI Listing
August 2018
7 Reads
3.183 Impact Factor

A possible role for domestic dogs in the spread of African horse sickness virus.

Authors:
Chris Oura

Vet Rec 2018 06;182(25):713-714

School of Veterinary Medicine, Faculty of Medical Sciences, University of the West Indies,Trinidad and Tobago.

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http://dx.doi.org/10.1136/vr.k2641DOI Listing
June 2018
1 Read

Physiological and immunological responses to Culicoides sonorensis blood-feeding: a murine model.

Parasit Vectors 2018 Jun 20;11(1):358. Epub 2018 Jun 20.

Arthropod-Borne Animal Diseases Research Unit, Agricultural Research Service, US Department of Agriculture, Manhattan, KS, 66502, USA.

Background: Hematophagous Culicoides spp. biting midges are of great agricultural importance as livestock, equine, and wildlife pests and as vectors of the orbiviruses bluetongue, epizootic hemorrhagic disease and African horse sickness. To obtain a blood meal, midges deposit saliva containing allergens, proteases, and anti-hemostatic factors, into the dermis to facilitate feeding. Read More

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http://dx.doi.org/10.1186/s13071-018-2935-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011595PMC
June 2018
5 Reads