4,348 results match your criteria Orbital Infections


Intracapsular hemorrhage rates in non-fixated nylon sheet orbital implants for orbital fracture management.

Am J Otolaryngol 2019 Apr 9. Epub 2019 Apr 9.

Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, USA; Department of Ophthalmology, Indiana University, Indianapolis, IN, USA; Oculofacial Plastic and Orbital Surgery, Indianapolis, IN, USA; St. Vincent Hospital, Indianapolis, IN, USA. Electronic address:

Purpose: To examine the incidence of intracapsular hemorrhage in orbital fracture repair with non-fixated nylon sheet implants.

Methods: A retrospective chart review of 227 patients presenting from January 2013 to December 2016 for orbital fracture repair with nylon sheet implants.

Results: Of the 331 orbital fractures repaired over 4 years, a total of 227 met inclusion criteria. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.04.008DOI Listing

Syrian Hamster as an Advanced Experimental Model for Visceral Leishmaniasis.

Methods Mol Biol 2019 ;1971:303-314

Department of Animal Health, ICPVet Research Group, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, Madrid, Spain.

Animal models are needed along the development and evaluation of potential chemotherapeutic agents against leishmaniasis. Infections of Syrian hamsters with Leishmania species causing visceral leishmaniasis (VL) closely mimic the disease in the natural hosts, including target organs, lesions, and clinical course. Therefore, despite some shortcomings (e. Read More

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http://link.springer.com/10.1007/978-1-4939-9210-2_17
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http://dx.doi.org/10.1007/978-1-4939-9210-2_17DOI Listing
January 2019
2 Reads

Studying Oxidative Stress Caused by the Mitis Group Streptococci in Caenorhabditis elegans.

J Vis Exp 2019 Mar 23(145). Epub 2019 Mar 23.

Department of Diagnostic and Biomedical Sciences, School of Dentistry, University of Texas Health Science Center;

Caenorhabditis elegans (C. elegans), a free-living nematode, has emerged as an attractive model to study host-pathogen interactions. The presented protocol uses this model to determine the pathogenicity caused by the mitis group streptococci via the production of H2O2. Read More

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http://dx.doi.org/10.3791/59301DOI Listing
March 2019
1 Read

Comparison of Clinical Results and Pathological Examinations Between Locally Synthesized Bone-derived Hydroxyapatite and Medpor® Orbital Implants in Animal Models.

Cureus 2019 Jan 25;11(1):e3954. Epub 2019 Jan 25.

Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.

We aimed to compare clinical and pathological reactions towards locally synthesized bovine bone derived from hydroxyapatite (bone docosahexaenoic acid (dHA)) and commercially available porous polyethylene (Medpor®, Porex Surgical Incorporation, Georgia, USA) orbital implants in animal models. An experimental study was performed on 14 New Zealand white rabbits. Group A (n=7) was implanted with bovine bone dHA and group B (n=7) was implanted with Medpor®. Read More

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http://dx.doi.org/10.7759/cureus.3954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436666PMC
January 2019
1 Read

Endogenous Panophthalmitis with Potential Entry Port from Diverticulitis Exacerbated by Proliferative Diabetic Retinopathy.

Case Rep Ophthalmol Med 2019 4;2019:3462459. Epub 2019 Mar 4.

SUNY Upstate Medical University, Department of Ophthalmology, Syracuse, NY, USA.

Purpose: To report a rapid endogenous fulminating panophthalmitis from in a patient with diverticulitis and proliferative diabetic retinopathy.

Methods: A 61-year-old female with poorly controlled diabetes mellitus, active proliferative diabetic retinopathy, and recent diverticulitis presented with conjunctival injection, ocular discharge, and sudden onset of painful vision loss of the left eye. Patient denied history of ocular trauma, intraocular surgery, or intravenous drug abuse. Read More

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https://www.hindawi.com/journals/criopm/2019/3462459/
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http://dx.doi.org/10.1155/2019/3462459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425300PMC
March 2019
4 Reads

Delayed diagnosis of a primary intraosseous squamous cell carcinoma: A case report.

Imaging Sci Dent 2019 Mar 25;49(1):71-77. Epub 2019 Mar 25.

Department of Anatomy, Biochemistry and Physiology, University of Hawai'i School of Medicine, Honolulu, HI, USA.

Primary intraosseous squamous cell carcinoma is a rare malignant central jaw tumor derived from odontogenic epithelial remnants. Predominantly, it affects mandible, although both jaw bones may be involved. This report describes a 60-year-old man who was initially misdiagnosed with a periapical infection related to the right lower wisdom tooth. Read More

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http://dx.doi.org/10.5624/isd.2019.49.1.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444010PMC
March 2019
1 Read

Correction of Complex Neurofibromatosis Orbital and Globe Malposition Using the Orbital Box Segmentation Osteotomy With Patient-Specific Internal Orbit Reconstruction.

J Craniofac Surg 2019 Mar 27. Epub 2019 Mar 27.

Department of Plastic and Reconstructive Surgery, Case Western Reserve University School of Medicine, Cleveland, OH.

Introduction: Correction of severe orbital and globe malposition from neurofibromatosis remains a significant clinical challenge. Current techniques including zygoma osteotomy, bone grafting, or placement of orbital implants do not adequately address aberrant anatomy, under-correct the deformity, and are prone to relapse. The authors have developed the orbital box segmentation osteotomy to reduce vertical orbital height and translocate the orbit and use patient-specific custom internal orbital titanium implants to close the cranio-orbital communication-reestablishing both the external orbital shape and internal orbital volume. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005369DOI Listing
March 2019
1 Read

Application of the three-dimensionally printed biodegradable polycaprolactone (PCL) mesh in repair of orbital wall fractures.

Authors:
So Young Kim

J Craniomaxillofac Surg 2019 Mar 15. Epub 2019 Mar 15.

Department of Plastic and Reconstructive Surgery, Inje University Sanggye Paik Hospital, Inje University School of Medicine, Seoul, South Korea. Electronic address:

Purpose: The present study aims to investigate the surface characteristics and biomechanical properties of 3D-printed polycaprolactone (PCL) mesh and present the clinical outcomes of this implant in the treatment of orbital wall fractures.

Patients And Method: A retrospective review of patients who underwent surgery for medial, inferior and inferomedial orbital wall fractures using PCL mesh was performed between April 2017 and June 2018. Two clinical outcomes were investigated: functional recovery and anatomical accuracy of reduction detected in image. Read More

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http://dx.doi.org/10.1016/j.jcms.2019.03.009DOI Listing
March 2019
1 Read

Cavernous sinus-orbital apex aspergillus infection in a diabetic patient: A case report.

Medicine (Baltimore) 2019 Mar;98(13):e15041

Department of Neurology, Southwest Hospital, The Third Military Medical University, Army Medical University, Chongqing, China.

Rationale: Cavernous sinus-orbital apex aspergillosis is a rare but serious complication of rhinosinusitis. Pathology results are scarce, and this condition is difficult to diagnose based on clinical and radiological results.

Patient Concerns: A 64-year-old woman presented with cavernous sinus-orbital apex syndrome. Read More

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http://dx.doi.org/10.1097/MD.0000000000015041DOI Listing
March 2019
2 Reads

Microdialysis Determination of Cefquinome Pharmacokinetics in Murine Thigh From Healthy, Neutropenic, and Infected Mice.

Front Pharmacol 2019 12;10:249. Epub 2019 Mar 12.

Guangdong Key Laboratory for Veterinary Drug Development and Safety Evaluation, South China Agricultural University, Guangzhou, China.

This study was aimed at applying microdialysis to explore cefquinome pharmacokinetics in thigh and plasma of healthy, neutropenic, and -infected mice. The relative recoveries (RRs) were tested by dialysis and retrodialysis and by retrodialysis. ICR mice were randomly divided into four groups: H-40 (healthy mice receiving cefquinome at 40 mg/kg), H-160, N-40 (neutropenic mice), and I-40 mg/kg (thigh infected-mice with ). Read More

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http://dx.doi.org/10.3389/fphar.2019.00249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422941PMC

Pediatric intraorbital abscess: Early recognition and management.

Clin Case Rep 2019 Mar 11;7(3):593-594. Epub 2019 Feb 11.

Craigavon Area Hospital (Southern Health and Social Care Trust) Portadown UK.

Orbital involvement occurs in 85% of complicated acute sinusitis and is more prevalent in children. Prompt differentiation between the more common periorbital (preseptal) cellulitis and infections, posterior to the orbital septum (including orbital cellulitis/abscess), is essential due to the latter's risk of irreversible optic neuropathy, intracranial spread and death. Read More

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http://dx.doi.org/10.1002/ccr3.2047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406159PMC
March 2019
1 Read

Clinicopathological Review of 547 Bulbar Enucleations in Hungary (2006-2017).

J Ophthalmol 2019 14;2019:2042459. Epub 2019 Feb 14.

Department of Ophthalmology, Semmelweis University, Budapest, Hungary.

Purpose: To analyse current clinicopathological enucleation indications in a large third-referral centre in a developed country (Hungary) over a period of 12 years.

Methods: Retrospective review was performed on 547 enucleated eyes of 543 patients (48.6% males, age 52. Read More

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http://dx.doi.org/10.1155/2019/2042459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393907PMC
February 2019
1 Read

Invasive Fungal Sinusitis: Risk Factors for Visual Acuity Outcomes and Mortality.

Ophthalmic Plast Reconstr Surg 2019 Mar 18. Epub 2019 Mar 18.

Department of Ophthalmology, University of California, San Francisco, San Francisco, California, U.S.A.

Purpose: Invasive fungal sinusitis is a rare but potentially lethal disease that primarily affects immunocompromised patients. The purpose of this study was to review an academic medical center's experience in the presentation, diagnosis, and treatment of invasive fungal sinusitis.

Methods: A retrospective chart review was performed at a single institution over a 17-year period. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001357DOI Listing
March 2019
8 Reads

Inflammatory Myofibroblastic Tumor of the Retroperitoneum Including Chronic Granulomatous Inflammation Suggesting Tuberculosis: A Case Report.

Ann Coloproctol 2019 Mar 20. Epub 2019 Mar 20.

Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.

An inflammatory myofibroblastic tumor (IMT) is a solid tumor of unknown etiology frequently affecting children and young adults and commonly affecting the lung or orbital region. We present a case involving a 41-year-old man who had an IMT combined with Mycobacterium tuberculosis infection in the retroperitoneum. He presented with only pain in the right lower abdomen without accompanying symptoms; a retroperitoneal mass was found on computed tomography. Read More

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http://dx.doi.org/10.3393/ac.2018.05.09DOI Listing
March 2019
1 Read

Post-traumatic endophthalmitis caused by .

JMM Case Rep 2019 Feb 20;6(2):e005175. Epub 2019 Feb 20.

Departament of Microbiology, University Hospital Marqués de Valdecilla - IDIVAL, Santander, Spain.

Introduction: complex has been associated with infections in both immunocompetent and immunocompromised patients. Infection can be localized or disseminated, affecting skin and soft tissues, the respiratory system, bones and joints, the circulatory system and especially the central nervous system. Ocular infections such as keratitis, scleritis, conjunctivitis, dacryocystitis, orbital cellulitis and endophthalmitis due to spp. Read More

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http://dx.doi.org/10.1099/jmmcr.0.005175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421342PMC
February 2019
3 Reads

Treating Pulsatile Exophthalmos in Child with Minimally Invasive Approach and Custom-made Titanium Mesh Plate.

Plast Reconstr Surg Glob Open 2019 Feb 11;7(2):e2070. Epub 2019 Feb 11.

Department of Plastic and Reconstructive Surgery, The University of Tokyo, Tokyo, Japan.

Orbital roof fracture is a relatively rare trauma. In most cases, surgical intervention is not needed since the fracture is slight. However, invasive surgical procedures are inevitable once pulsatile exophthalmos occurs if vision impairment is to be avoided. Read More

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http://dx.doi.org/10.1097/GOX.0000000000002070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416129PMC
February 2019
1 Read

Fatal renal mucormycosis with Apophysomyces elegans in an apparently healthy male.

Aging Male 2019 Mar 16:1-4. Epub 2019 Mar 16.

a Department of Laboratory Medicine and Pathology , Hamad General Hospital , Doha , Qatar.

Mucor is an angioinvasive fungus that was reported mainly in immunocompromised patients. It usually presents as rhino-orbital, pulmonary, gastrointestinal, and disseminated disease. Isolated renal mucormycosis is an extremely rare infection in immunocompetent patients and is associated with high fatality rate. Read More

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http://dx.doi.org/10.1080/13685538.2019.1586871DOI Listing
March 2019
2 Reads

What Is the Best Treatment for a Subperiosteal Abscess? A Case Report in a Pediatric Patient.

J Pediatr Health Care 2019 Mar 11. Epub 2019 Mar 11.

Subperiosteal abscess is a condition that typically presents as collection of pus in the space between the periorbital and the lamina papyracea as a result of the migration and spread of an infection, such as sinusitis and ethmoiditis. The low incidence requires a high index of suspicion to be considered in the differential diagnosis when encountering this life-threatening illness. This case highlights the significance of a prompt and accurate diagnosis for this infrequent condition, because it may progress to blindness, meningitis, intracranial abscess, and death. Read More

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http://dx.doi.org/10.1016/j.pedhc.2019.01.003DOI Listing
March 2019
1 Read

Acute Hepatitis in Infections Caused by Dengue Virus in Southern Punjab, Pakistan.

Cureus 2018 Dec 28;10(12):e3788. Epub 2018 Dec 28.

Internal Medicine, Quaid-E-Azam Medical College, Bahawalpur, PAK.

Background Dengue is the most common vector-borne disease worldwide. It poses a significant health burden in tropical and subtropical countries. Common clinical presentations include retro-orbital pain, fever, headache, nausea, vomiting and aches and pains in the body. Read More

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http://dx.doi.org/10.7759/cureus.3788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402748PMC
December 2018
2 Reads

Orbital Nasal-Type Extranodal Natural Killer/T-Cell Lymphoma: An Ongoing Diagnostic Challenge Further Confounded by Small-Cell Predominance.

Ophthalmic Plast Reconstr Surg 2019 Mar 8. Epub 2019 Mar 8.

Division of Ophthalmic Plastic and Reconstructive Surgery, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.

Purpose: To highlight the histopathologic diagnostic challenges of small-cell predominant extranodal nasal-type natural killer/T-cell lymphoma (ENTNKT) of the orbit.

Methods: Retrospective chart review and histopathologic study with immunohistochemistry and in situ hybridization of 3 cases.

Results: Three cases of ENTNKT presented to the Mass Eye and Ear emergency room as orbital cellulitis over 1 year. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001333DOI Listing
March 2019
4 Reads

Bioresorbable Material in Secondary Orbital Reconstruction Surgery.

J Ophthalmol 2019 3;2019:8715314. Epub 2019 Feb 3.

Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Purpose: To validate the potential of bioresorbable implantation in secondary revisional reconstruction after inadequate primary orbital fracture repair, with assessment of pre- and postoperative clinical characteristics and computed tomography image findings.

Methods: A retrospective chart review was conducted on 16 consecutive patients treated for orbital fractures at Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, with inadequate prior surgeries between July 2010 and June 2017; patients who had suffered orbital blowout fractures had undergone primary surgeries elsewhere. Secondary repair of orbital fractures used bioresorbable material following unsatisfactory primary orbital repair. Read More

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https://www.hindawi.com/journals/joph/2019/8715314/
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http://dx.doi.org/10.1155/2019/8715314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377963PMC
February 2019
2 Reads

Diagnosis and treatment of a penetrating brain injury caused by a welding electrode: A case report.

Medicine (Baltimore) 2019 Mar;98(10):e14528

Department of Neurotraumatology.

Rationale: Penetrating brain injury caused by a welding electrode is a rare occurrence. This type of injury requires careful preoperative assessment and timely treatment measures to avoid secondary damage.

Patient Concerns: A 55-year-old male patient fell from a height of approximately 5 m during when a welding electrode in his left hand was inadvertently inserted into his brain. Read More

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http://dx.doi.org/10.1097/MD.0000000000014528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417516PMC
March 2019
3 Reads

A rare case of invasive sino-orbital aspergillosis arising from isolated frontal sinus infection.

Can J Ophthalmol 2019 Feb 19;54(1):e19-e21. Epub 2018 Jun 19.

University of Adelaide, Adelaide, Australia; South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, Australia.

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http://dx.doi.org/10.1016/j.jcjo.2018.04.022DOI Listing
February 2019
1 Read

Microbial Keratitis in Thyroid Eye Disease: Clinical Features, Microbiological Profile, and Treatment Outcome.

Ophthalmic Plast Reconstr Surg 2019 Mar 5. Epub 2019 Mar 5.

Ophthalmic Plastic Surgery Service, L.V. Prasad Eye Institute, Hyderabad, India; Jhaveri Microbiology laboratory, L.V. Prasad Eye Institute, Hyderabad, India; and Tej Kohli Cornea Insititute, L.V. Prasad Eye Institute, Hyderabad, India.

Purpose: To report the incidence, clinical features, microbiologic profile, and risk indicators in the development of microbial keratitis in Thyroid Eye Disease (TED).

Methods: All patients who were diagnosed to have TED and developed microbial keratitis between the years 2009 to 2017 at the Ophthalmic Plastic Surgery service, LV Prasad Eye Institute were included in this retrospective interventional study. The clinical features, microbiological profile, and treatment outcome of the infection were studied. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001361DOI Listing
March 2019
2 Reads

First Case of Cutaneous Orbital Abscess Caused by Gemella: A Case Report and Review of the Literature.

J Oral Maxillofac Surg 2019 Feb 5. Epub 2019 Feb 5.

Clinical Professor of Surgery, Department of Surgery, FACES, Charleston Area Medical Center, Charleston, WV. Electronic address:

This is the first report of an orbital abscess caused by Gemella bergeri, uncommonly identified in cardiac valvular infections. Through matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF MS), microbial identification and speciation resulted in timely identification and appropriate management. Successful management includes accurate microbial identification, incision and drainage, and broad-spectrum antibiotics. Read More

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http://dx.doi.org/10.1016/j.joms.2019.01.049DOI Listing
February 2019

Orbital apex syndrome caused by Alternaria species: A novel invasive fungus and new treatment paradigm.

Orbit 2019 Mar 1:1-4. Epub 2019 Mar 1.

a Vanderbilt University Medical Center , Nashville , TN , USA.

Orbital apex syndrome as a result of invasive fungal sinusitis is a disease entity most commonly found in immunocompromised patients. Infectious invasion affecting the orbital apex can have devastating visual and life-threatening consequences. Mucormycosis and Aspergillus species are the most common causes of such infections. Read More

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http://dx.doi.org/10.1080/01676830.2019.1582071DOI Listing
March 2019
1 Read

Fatal Oculocutaneous Ecthyma Gangrenosum in Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome: Case Report and Review of the Literature.

J Glob Infect Dis 2019 Jan-Mar;11(1):43-46

Department of Internal Medicine, University of Calabar, Calabar, Cross River State, Nigeria.

Ecthyma gangrenosum (EG) is a rare, infective skin disease, predominantly but not exclusively caused by . It is often seen in individuals with immunosuppression, although it has also been reported among previously healthy individuals. It was initially thought to be pathognomonic of septicemia, but this assertion was discarded following several reports on EG without bacteremia and EG with varied bacterial and fungal etiologies. Read More

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http://dx.doi.org/10.4103/jgid.jgid_54_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380104PMC
March 2019
5 Reads

Scedosporium apiospermum: A Rare Cause of Aggressive Orbital Apex Syndrome.

Cureus 2018 Dec 17;10(12):e3743. Epub 2018 Dec 17.

Ophthalmology, Hospital Tengku Ampuan Rahimah, Klang, MYS.

Orbital apex syndrome (OAS) is a localized orbital cellulitis at the orbital apex that can cause vision loss from optic neuropathy and ophthalmoplegia involving multiple cranial nerves. Herein, we report a rare and rapidly progressive case of OAS secondary to fungal pansinusitis caused by in an immunocompromised patient following the extraction of abscessed teeth. A 48-year-old man with diabetes mellitus who had failed to adhere to his treatment presented with complaints of a right-sided headache and toothache for two weeks, with nausea and vomiting for two days prior to presentation. Read More

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http://dx.doi.org/10.7759/cureus.3743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384044PMC
December 2018
2 Reads

Common Community-acquired Bacterial Skin and Soft-tissue Infections in Children: an Intersociety Consensus on Impetigo, Abscess, and Cellulitis Treatment.

Clin Ther 2019 Mar 15;41(3):532-551.e17. Epub 2019 Feb 15.

Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

Purpose: The main objective of this article was to offer practical suggestions, given the existing evidence, for identifying and managing bacterial impetigo, abscess, and cellulitis in ambulatory and hospital settings.

Methods: Five Italian pediatric societies appointed a core working group. In selected conditions, specially trained personnel evaluated quality assessment of treatment strategies according to the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology. Read More

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http://dx.doi.org/10.1016/j.clinthera.2019.01.010DOI Listing
March 2019
7 Reads
2.731 Impact Factor

Pediatric preseptal and orbital cellulitis: A 10-year experience.

Int J Pediatr Otorhinolaryngol 2019 May 7;120:82-88. Epub 2019 Feb 7.

Pediatrics Department, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal.

Objective: Characterize clinical features, epidemiology and treatment of hospitalized pediatric cases of preseptal and orbital cellulitis.

Methods: Retrospective study of children/adolescents admitted to a central hospital with preseptal and orbital cellulitis between 2007 and 2017.

Results: A total of 122 cases were included, 80. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.02.003DOI Listing
May 2019
1 Read

Prevalence and clinical patterns of ocular complications associated with anti-PD-1/PD-L1 anticancer immunotherapy.

Am J Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Assistance Publique Hôpitaux de Paris, Hôpital Bicêtre, Service d'Ophtalmologie, DHU Vision & Handicaps, Centre de référence pour les maladies rares en ophtalmologie (OPHTARA), F-94275, Le Kremlin-Bicêtre, France; Université Paris-Sud, F-94276, Le Kremlin-Bicêtre, France; INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases, F-94276, Le Kremlin-Bicêtre, France; CEA, DSV/iMETI, IDMIT, F-92265, Fontenay-aux-Roses, France Department of Immunology of viral and auto-immune disease, (IMVA/ IDMIT), UMR1184, CEA, Fontenay-aux-Roses. Electronic address:

Purpose: Immune checkpoint inhibitors (ICI) targeting the programmed cell death protein 1 (PD-1), or its ligand PD-L1, are the mainstay of metastatic cancer treatment. Patients receiving these treatments may develop immune-related adverse events (irAEs). This study aimed to estimate the prevalence and describe the clinical patterns of moderate to severe ocular irAEs-associated with anti-PD-(L)1 treatment. Read More

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http://dx.doi.org/10.1016/j.ajo.2019.02.012DOI Listing
February 2019
3 Reads

Invasive sino-orbital fungal infections in immunocompetent patients: a clinico-pathological study.

Eye (Lond) 2019 Feb 14. Epub 2019 Feb 14.

Department of Orbit, Oculoplasty & Ocular Oncology, Aravind Eye Hospital, Madurai, India.

Objective: Invasive sino-orbital fungal infections in immunocompetent patients are a rare clinical entity; the diagnosis and management of which is challenging. We present a large case series of invasive sino-orbital fungal granulomas in patients without pre-existing systemic immunocomprimising condition.

Design: Retrospective case series. Read More

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http://dx.doi.org/10.1038/s41433-019-0358-6DOI Listing
February 2019
1 Read

Pulmonary Mucormycosis (Zygomycosis) Presenting as an Infective Exacerbation of Chronic Obstructive Pulmonary Disease.

Eur J Case Rep Intern Med 2018 27;5(12):000995. Epub 2018 Dec 27.

Department of Respiratory Medicine, Nicosia General Hospital, Cyprus.

Mucormycosis is a life-threatening fungal infection whose incidence has been rising recently, mainly due to the increasing use of immunosuppressive and corticosteroid treatment. In previous decades, mucormycosis was associated with a very poor prognosis as mortality was approximately 100%. Mortality rates reported in recent literature have only slightly improved despite the availability of targeted therapy with amphotericin B. Read More

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http://dx.doi.org/10.12890/2018_000995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346968PMC
December 2018
7 Reads

A Classic Neurocysticercosis Case with an Unusual Complication.

Eur J Case Rep Intern Med 2018 31;5(1):000762. Epub 2018 Jan 31.

Infectious Diseases Department, Hospital de Santa Maria, Lisbon, Portugal.

Cysticercosis is triggered by infection with the larval form of the tapeworm . The usual sites for the development of cyscticerci are the central nervous system (neurocysticercosis - NCC), subcutaneous tissue, skeletal muscle, heart muscle, and the eye. Ocular cysticercosis is caused by the growth of the larvae within ocular tissues. Read More

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http://dx.doi.org/10.12890/2017_000762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346944PMC
January 2018
1 Read

Orbital Subperiosteal Abscess Associated with Mandibular Wisdom Tooth Infection: A Case Report.

J Maxillofac Oral Surg 2019 Mar 14;18(1):30-33. Epub 2017 Dec 14.

3Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Medical Sciences and Technology, Khartoum, Sudan.

Background: Orbital infection related to mandibular third molar infection is extremely rare. Most of cases reported in literature are related to maxillary molar teeth. Odontogenic infections are not common causes of orbital abscess but it should always be put in consideration when dealing with orbital cellulitis and abscess. Read More

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http://dx.doi.org/10.1007/s12663-017-1074-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328831PMC
March 2019
6 Reads

Unravelling species boundaries in the complex (section ): opportunistic human and animal pathogens capable of interspecific hybridization.

Persoonia 2018 Dec 21;41:142-174. Epub 2018 Jun 21.

Laboratory of Fungal Genetics and Metabolism, Institute of Microbiology of the CAS, v.v.i, Vídeňská 1083, 142 20 Prague 4, Czech Republic.

Although is the major agent of invasive aspergillosis, an increasing number of infections are caused by its cryptic species, especially and the species complex (AVSC). Their identification is clinically relevant because of antifungal drug resistance and refractory infections. Species boundaries in the AVSC are unresolved since most species have uniform morphology and produce interspecific hybrids . Read More

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http://dx.doi.org/10.3767/persoonia.2018.41.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344812PMC
December 2018

Acute Bilateral Oculomotor Nerve Palsy in an Adult Patient with Neisseria meningitidis.

Intern Med 2019 Feb 1. Epub 2019 Feb 1.

Department of Cardiology, Komaki City Hospital, Japan.

A 69-year-old woman was admitted to our hospital with a fever, dizziness, and headache caused by Neisseria meningitidis. After ceftriaxone was administered, she suddenly developed bilateral oculomotor nerve palsy. Intra-orbital magnetic resonance imaging using appropriate sequences revealed that her bilateral third intracranial nerves were enlarged and enhanced. Read More

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http://dx.doi.org/10.2169/internalmedicine.2098-18DOI Listing
February 2019
9 Reads

Comparisons among four types of absorbable plates used for internal fixation of zygomaticomaxillary complex fractures.

J Craniomaxillofac Surg 2019 Mar 17;47(3):383-388. Epub 2019 Jan 17.

Department of Plastic and Reconstructive Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea. Electronic address:

Importance: Conventional plating systems include titanium plates for the fixation of facial bone fractures. However, titanium plates result in artifacts on computed tomography images and appear unstable on magnetic resonance images. Therefore, absorbable plates have been widely used for the fixation of facial bone fractures of late in Asia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10105182183077
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http://dx.doi.org/10.1016/j.jcms.2019.01.014DOI Listing
March 2019
5 Reads

A ten year study of prevalence, antimicrobial susceptibility pattern, and genotypic characterization of Methicillin resistant Staphylococcus aureus causing ocular infections in a tertiary eye care hospital in South India.

Infect Genet Evol 2019 Apr 30;69:203-210. Epub 2019 Jan 30.

Department of Ocular Microbiology, Aravind Eye Hospital, Madurai, India. Electronic address:

Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of vision threatening ocular infections. This study aimed to determine the prevalence and antimicrobial susceptibility pattern of MRSA and their genotypic characterization in ocular infections. The study period was from January 2007 to December 2017 in Aravind Eye Hospital, Madurai. Read More

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http://dx.doi.org/10.1016/j.meegid.2019.01.031DOI Listing
April 2019
2 Reads

Primary replacement for the management of exposed orbital implant.

Orbit 2019 Feb 1:1-7. Epub 2019 Feb 1.

f The Sussex Eye Hospital , Brighton and Sussex University Hospital , Brighton , UK.

Purpose: We present a series of primary orbital implant replacement for cases of implant exposure to describe our experience of this one-staged surgical approach.

Methods: This study reports on a one-stage technique which involved the removal of the exposed implant or dermis fat graft (DFG) and insertion of a secondary (replacement) in the same procedure, with a variety of materials, including autologous tissue. Re-exposure in a socket where a DFG was placed was defined as a new defect in the newly epithelialized conjunctiva or dehiscence of the dermis-conjunctiva junction. Read More

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https://www.tandfonline.com/doi/full/10.1080/01676830.2019.1
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http://dx.doi.org/10.1080/01676830.2019.1573262DOI Listing
February 2019
4 Reads

Successful treatment of invasive fungal rhinosinusitis caused by : A case report and review of the literature.

World J Clin Cases 2019 Jan;7(2):228-235

Department of Pathology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.

Background: Invasive fungal rhinosinusitis (IFR) caused by is very rare but has an extremely high fatality rate. There have been only seven cases of IFR caused by reported in English and, of these, only three patients survived. In this article, we present another case of IFR caused by , in which the patient was initially treated successfully but then deteriorated due to a relapse of leukemia 2 mo later. Read More

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https://www.wjgnet.com/2307-8960/full/v7/i2/228.htm
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http://dx.doi.org/10.12998/wjcc.v7.i2.228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354086PMC
January 2019
10 Reads

[Orbital apex syndrome secondary to nasal herpes zoster virus infection: one case report].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Jan;54(1):50-51

Department of Otorhinolaryngology Head and Neck Surgery, Second Hospital of Jilin University, Changchun 130041, China.

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2019.01.011DOI Listing
January 2019
1 Read

A rare case of septic cavernous sinus thrombosis as a complication of sphenoid sinusitis.

Ci Ji Yi Xue Za Zhi 2019 Jan-Mar;31(1):63-65

Department of Pediatrics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.

Isolated sphenoid sinusitis is a rare disorder and may present with severe complications due to its proximity to the orbital and intracranial areas. We report a 13-year-old boy hospitalized for septic shock with fever of unknown origin. Facial palsy was later noted. Read More

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http://dx.doi.org/10.4103/tcmj.tcmj_1_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334571PMC
January 2019
3 Reads

Management of median and paramedian craniofacial clefts.

J Plast Reconstr Aesthet Surg 2019 Apr 9;72(4):676-684. Epub 2019 Jan 9.

Division of Plastic, Reconstructive and Esthetic Surgery, Department of Surgery, Geneva University Hospitals and Faculty of Medicine, 4 Rue Gabrielle Perret-Gentil, 1211 Geneva 14, Switzerland.

Background: Median and paramedian craniofacial clefts are associated with hypertelorism, anterior encephalocele, positional abnormalities of the maxilla, and nasal deformity. Cleft lip and palate, eyelid coloboma, and widow's peak are frequently present.

Methods: The authors collected data from 30 patients (mean age, 5. Read More

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http://dx.doi.org/10.1016/j.bjps.2019.01.001DOI Listing
April 2019
2 Reads

Bone wax migrates to the orbit in a patient with a frontal sinus abnormality: a case report.

BMC Ophthalmol 2019 Jan 24;19(1):29. Epub 2019 Jan 24.

Department of Ophthalmology, the 2nd Xiangya Hospital, Central South University, Changsha, 410011, Hunan Province, China.

Background: Bone wax is the most widely used hemostatic bone sealant because of its availability, ease of use, immediate action, and minimal adverse effects. Several complications have been reported to be associated with the use of bone wax, such as infection, osteohypertrophy, pain, granuloma formation, allergic reaction, and thrombosis. Here, we present a rare complication, namely, bone wax migration, which developed after a craniotomy on a patient who had a frontal sinus abnormality. Read More

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http://dx.doi.org/10.1186/s12886-019-1037-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345031PMC
January 2019
3 Reads

Varicella zoster virus reactivation antedating ipsilateral brainstem stroke.

Dermatol Online J 2018 Aug 15;24(8). Epub 2018 Aug 15.

Department of Biomedical, Metabolic, Neural Sciences, University Hospital of Modena.

itor Title: Varicella zoster virus reactivation antedating ipsilateral brainstem stroke Authors: Giuliana Galassi1, Maurilio Genovese2, Marisa Meacci3, Marcella Malagoli2 Affiliations: 1Department of Biomedical, Metabolic, Neural Sciences, University Hospital of Modena, Italy, 2Neuroradiology Service, University Hospital of Modena, Italy, 3Department of Laboratory Medicine and Patholgy, Microbiology and Virology Unit, University Hospital of Modena, Italy Corresponding Author: Giuliana Galassi, MD, Department of Biomedical, Metabolic, Neural Sciences, University Hospital of Modena, Via P. Giardini 1455, Modena, Italy, Tel: 39-3497325802, Email: giulianagalassi46@gmail.com Abstract: Varicella zoster virus (VZV) infection and reactivation are associated with a number of neurologic conditions. Read More

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August 2018
1 Read

Two cases of Osteoarticular Mucor menace: A diagnostic and management conundrum.

Drug Discov Ther 2018 ;12(6):374-378

Department of Medicine, All India Institute of Medical Sciences.

Mucormycosis is an uncommon aggressive fungal infection usually seen in immunocompromised hosts or patients with burns and trauma. The common presentations include rhino-orbital-cerebral and pulmonary involvement. Osteoarticular involvement is a rare presentation of this disease. Read More

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http://dx.doi.org/10.5582/ddt.2018.01064DOI Listing
January 2018
3 Reads

A Comparison of Endoscopic Reduction for Medial Blowout Fractures Using a Bioresorbable Panel and Silastic Sheet.

J Craniofac Surg 2019 Jan 17. Epub 2019 Jan 17.

Department of Otolaryngology Head-Neck Surgery, Kosin University College of Medicine.

Background: The aim of the study was to compare the effectiveness of endoscopic endonasal reduction using a bioresorbable panel and silastic sheet packed with Merocel for blowout fractures of the medial orbital wall.

Design: Retrospective study.

Methods: The study group consisted of 147 patients who underwent endoscopic endonasal reduction of a blowout fracture of the medial orbital wall between January 2005 and December 2016. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005083DOI Listing
January 2019
12 Reads

Sinonasal-Related Orbital Infections in Children: A Clinical and Therapeutic Overview.

J Clin Med 2019 Jan 16;8(1). Epub 2019 Jan 16.

Otolaryngological Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Sinonasal-related orbital infections (SROIs) are typically pediatric diseases that occur in 3⁻4% of children with acute rhinosinusitis. They are characterised by various clinical manifestations, such as peri-orbital and orbital cellulitis or orbital and sub-periosteal abscesses that may develop anteriorly or posteriorly to the orbital septum. Posterior septal complications are particularly dangerous, as they may lead to visual loss and life-threatening events, such as an intracranial abscess and cavernous sinus thrombosis. Read More

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http://www.mdpi.com/2077-0383/8/1/101
Publisher Site
http://dx.doi.org/10.3390/jcm8010101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351922PMC
January 2019
6 Reads