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    1 OF 83

    Eye for an eye: near-fatal outcome of fungal infection in a young, diabetic girl.
    BMJ Case Rep 2018 Apr 17;2018. Epub 2018 Apr 17.
    Department of Otolaryngology, Academic Medical Centre, Amsterdam, The Netherlands.
    In this report, we describe the case of a young, diabetic girl with ketoacidosis who suffered sudden loss of vision of the right eye. The loss of vision was caused by an invasive rhino-orbital-cerebral fungal infection (mucormycosis) with extensive periorbital thrombosis. Despite maximal antifungal and surgical treatment (including exenteration of the right orbit), the clinical situation deteriorated. Read More

    Maxillary sinus mucocele with orbital complications.
    Ann Ital Chir 2018 Apr 9;7. Epub 2018 Apr 9.
    Introduction: Maxillary sinus mucocele is an unusual clinic entity (incidence of 3-10%), represented by mucous secretion lined by respiratory stratified pavemented epithelium and its origin is mainly secondary to infections, inflammations, surgery, trauma or neoplasia.

    Case Report: We present a case of maxillary sinus mucocele. Subject of the study is a 74 aged patient referring positive anamnesis for nasal cavity surgery. Read More

    Mucormycosis of the paranasal sinuses in a patient with acute myeloid leukemia.
    Srp Arh Celok Lek 2016 Nov-Dec;144(11-12):657-60
    Introduction: Invasive fungal infection is among the leading causes of morbidity, mortality, and economic burden for patients with acute leukemia after induction of chemotherapy. In the past few decades, the incidence of invasive fungal infection has increased dramatically. Its management has been further complicated by the increasing frequency of infection by non-Aspergillus molds (e. Read More

    A case report of orbital Langerhans cell histiocytosis presenting as a orbital cellulitis.
    Arch Soc Esp Oftalmol 2018 Apr 8. Epub 2018 Apr 8.
    Unidad de Órbita y Oculoplástica, Servicio de Oftalmología, Hospital Universitario de Gerona Dr. Josep Trueta, Gerona, España.
    Clinical Case: A 10-year-old girl was seen with a 3-week history of right upper lid swelling and with no other symptoms or fever. There was no recent history of sinusitis, trauma, or previous infection involving the periorbital area, or response to oral antibiotic treatment. Orbital computed tomography showed a lesion involving the upper margin of the orbit, and bone destruction at the orbital roof. Read More

    Mucormycosis: Battle with the Deadly Enemy over a Five-Year Period in India.
    J Fungi (Basel) 2018 Apr 6;4(2). Epub 2018 Apr 6.
    Mycology Unit, Medical School and IISPV, Universitat Rovira I Virgili, 43201 Reus, Spain.
    Mucormycosis is an emerging opportunistic fungal infection. Increasing immunocompromization, widespread use of antibacterial and antifungal agents (such as voriconazole prophylaxis), carcinomas, transplantation and lifestyle diseases such as diabetes are the main contributors to this situation. The predominant clinical manifestations of mucormycosis vary from host to host, with rhino-orbital-cerebral, pulmonary, cutaneous, and gastrointestinal infections being the most common. Read More

    Clostridium perfringens panophthalmitis and orbital cellulitis: a case report.
    BMC Ophthalmol 2018 Apr 10;18(1):88. Epub 2018 Apr 10.
    Clinical Bacteriology Department, Amiens-Picardie University Hospital, Amiens, France.
    Background: Clostridium perfringens is an uncommon pathogen in endophthalmitis, causing rapid destruction of ocular tissues. Clostridium perfringens infection typically occurs after penetrating injury with soil-contaminated foreign bodies.

    Case Report: Here, we describe the case of a 17-year-old male who sustained a penetrating injury with a metallic intraocular foreign body and who rapidly developed severe C. Read More

    Invasive meningococcal disease due to a non-capsulated Neisseria meningitidis strain in a patient with IgG4-related disease.
    BMC Infect Dis 2018 Apr 2;18(1):146. Epub 2018 Apr 2.
    Division of Infectious Diseases, Fukuoka City Hospital, 13-1 Yoshizuka-Honmachi, Hakata-ku, Fukuoka, 812-0046, Japan.
    Background: Invasive Meningococcal Disease (IMD) is a rare and critical disease in Japan. Most of these cases are caused by capsulated Neisseria meningitidis strains. Non-capsulated (non-typable) strains are considered relatively low-pathogenic and can colonize in the nasopharynx of healthy children and young adults. Read More

    Management of a Severe Cervicofacial Odontogenic Infection.
    J Contemp Dent Pract 2018 Mar 1;19(3):352-355. Epub 2018 Mar 1.
    Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Pernambuco, Camaragibe, Brazil.
    Introduction: Odontogenic infections originate from a tooth or from its supporting structures, generally secondary to a pulp necrosis, periodontal disease, pericoronitis, apical lesions, or complications of dental procedures, which can be restricted to the alveolus or can reach the jaws and face through maxillofacial spaces. These are the most common conditions which affect the head and neck regions.

    Aim: The aim of this study is to report a severe case of a cervicofacial odontogenic infection while discussing the most relevant aspects. Read More

    Gastric Mucormycosis in a Liver and Kidney Transplant Recipient: Case Report and Concise Review of Literature.
    Transplant Proc 2018 Apr 22;50(3):905-909. Epub 2018 Mar 22.
    Nephrology Dialysis and Transplant Unit, University of Modena and Reggio Emilia, AOU Policlinico of Modena, Modena, Italy.
    Mucormycosis is an uncommonly encountered fungal infection in solid organ transplantation. The infection is severe and often results in a fatal outcome. The most common presentations are rhino-sino-orbital and pulmonary disease. Read More

    Surgical Treatment of Rhinosinusitis-Related Orbital Complications: Factors Affecting Irreversible Blindness.
    J Craniofac Surg 2018 Mar 22. Epub 2018 Mar 22.
    Department of Otorhinolaryngology, Faculty of Medicine.
    If left untreated, rhinosinusitis can rarely cause a devastating complication irreversible blindness (IB). Despite new technologies in endoscopic sinus surgery and use of new broad-spectrum antibiotics, IB outcome is still a problem for surgically treated orbital complication of paranasal sinus infection (OCPSI) patients, and factors leading to IB outcome are not actually known. The aim of this study was to assess the factors leading to the IB outcome for surgically treated OCPSI patients. Read More

    Ocular surface squamous neoplasia in HIV-infected patients: current perspectives.
    HIV AIDS (Auckl) 2018 14;10:33-45. Epub 2018 Mar 14.
    Operation Eyesight Universal Institute for Eye Cancer, LV Prasad Eye Institute, Hyderabad, India.
    Ocular surface squamous neoplasia (OSSN) refers to a spectrum of conjunctival and corneal epithelial tumors including dysplasia, carcinoma in situ, and invasive carcinoma. In this article, we discuss the current perspectives of OSSN associated with HIV infection, focusing mainly on the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of these tumors in patients with HIV. Upsurge in the incidence of OSSN with the HIV pandemic most severely affected sub-Saharan Africa, due to associated risk factors, such as human papilloma virus and solar ultraviolet exposure. Read More

    The Role of Aging, Drug Dependence, and Hepatitis C Comorbidity in Alcoholism Cortical Compromise.
    JAMA Psychiatry 2018 Mar 14. Epub 2018 Mar 14.
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California.
    Importance: The prevalence of alcohol misuse increased substantially over a decade in adults, particularly in those aged 65 years or older. Ramifications for brain structural integrity are significant, especially in older adults.

    Objectives: To combine cross-sectional, longitudinal data to test age-alcoholism interactions and examine the association between prevalent comorbidities (drug dependence and hepatitis C virus [HCV] infection) and cortical volume deficits in alcohol dependence. Read More

    Twenty-Year Outcome Experience With Open Craniosynostosis Repairs: An Analysis of Reoperation and Complication Rates.
    Ann Plast Surg 2018 Mar 13. Epub 2018 Mar 13.
    Background: Surgical intervention during infancy for both syndromic and nonsyndromic patients with craniosynostosis remains the criterion standard of treatment with the 2 main options being open vault remodeling versus minimally invasive surgery. Although open cranial vault remodeling was initially considered a high-risk procedure, many advances have improved its safety. Despite this, there is a paucity of literature on the long-term outcomes of contemporary open craniosynostosis repair. Read More

    Varicella zoster causing preseptal cellulitis - uncommon but possible.
    Malays Fam Physician 2017 31;12(3):37-39. Epub 2017 Dec 31.
    (Corresponding author) MBBs (Bangalore), Ms ORL-HNS (UKM) Department of Otorhinolaryngology-Head and Neck Surgery, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, Malaysia email:
    Background: Varicella has been known to be a harmless childhood disease. However, it has been reported that severe complications have taken place following Varicella infection, in both immunocompetent, as well as immunocompromised, individuals. Cutaneous complications of Varicella may manifest as preseptal cellulitis, albeit rarely. Read More

    Saksenaea vasiformis Orbital Cellulitis in an Immunocompetent Child Treated With Posaconazole.
    J Pediatric Infect Dis Soc 2018 Mar 7. Epub 2018 Mar 7.
    Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.
    An 11-year-old immunocompetent girl presented with two and a half months of progressive right orbital cellulitis, which did not respond to multiple courses of antibiotics or prednisone. A panfungal polymerase chain reaction primer was positive for Saksenaea vasiformis, and she completed 5 months of oral posaconazole therapy after debridement. Saksenaea vasiformis is a rare cause of zygomycosis, and it typically causes skin and soft tissue infection in immunocompetent hosts, particularly after a traumatic injury. Read More

    Dengue fever in renal allograft recipients: Clinical course and outcome.
    Transpl Infect Dis 2018 Mar 7:e12875. Epub 2018 Mar 7.
    Department of Nephrology, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
    Background: There are annual outbreaks of dengue infection in tropical and subtropical countries. This retrospective study aimed to assess the clinical manifestation of dengue and outcome in renal transplant recipients.

    Methods: Renal transplant recipients diagnosed with dengue in the nephrology department during the outbreak from August 2015 to December 2015 were included in the study. Read More

    Retrobulbar abscess: rare complication after repair of an oroantral communication.
    Br J Oral Maxillofac Surg 2018 Apr 2;56(3):227-229. Epub 2018 Mar 2.
    Oral & Maxillofacial Surgery, Bradford Royal Infirmary, Duckworth Lane, Bradford BD9 6RJ. Electronic address:
    We present the case of a retrobulbar abscess that developed secondary to the repair of an oroantral communication. Orbital abscesses have been described in relation to odontogenic infections, facial injury, sinusitis, and after dental extractions but, to the best of our knowledge, none has been reported in these circumstances. Retrobulbar abscess is a rare complication, but early clinical and radiological diagnosis, and urgent decompression are vital because it comes with considerable risk of irreversible visual impairment. Read More

    Orbital Inflammatory Complications of Crohn's Disease: A Rare Case Series.
    Clin Med Insights Gastroenterol 2018 20;11:1179552218757512. Epub 2018 Feb 20.
    Nottingham Digestive Diseases Centre, National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK.
    Orbital inflammatory disease is a rare ophthalmic manifestation of Crohn's disease. Inflammation is characteristically nonspecific, involving one or multiple structures of the orbit. Mechanisms of disease and optimal methods of treatment are poorly understood. Read More

    Evaluation of patients with orbital infections.
    Turk Pediatri Ars 2017 Dec 1;52(4):221-225. Epub 2017 Dec 1.
    Istanbul University, Cerrahpaşa Medical Faculty, Department of Pediatrics, Division of Immunology-Allergy and Infectious Diseases, Istanbul, Turkey.
    Aim: Orbital tissue infections are common infections of childhood that can lead to severe complications. Herein, we aimed to evaluate the etiologic factors, diagnosis, follow-up, and treatment procedures in pediatric patients with orbital infections.

    Material And Methods: This study was performed retrospectively between January 2014 and December 2015 in Cerrahpasa Medical Faculty Pediatric Infectious Disease Unit. Read More

    Orbital apex syndrome from bacterial sinusitis without orbital cellulitis.
    Am J Ophthalmol Case Rep 2018 Jun 31;10:84-86. Epub 2018 Jan 31.
    Ruiz Department of Ophthalmology and Visual Science, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), 6431 Fannin St., MSB 7.024, Houston, TX, 77030, United States.
    Purpose: To describe a case of orbital apex syndrome as a result of isolated bacterial sinusitis.

    Observations: A 63-year-old woman presented with an orbital apex syndrome from isolated bacterial sinusitis with rapidly declining visual acuity to no light perception. We compared our case with 6 similar cases of severe vision loss from isolated bacterial sinusitis. Read More

    [Management of Rhinosinusitis in Primary Care].
    Semergen 2018 Feb 13. Epub 2018 Feb 13.
    Centro de Salud Camargo Costa, Maliaño, Cantabria, España.
    Acute rhinosinusitis is an important health problem. Even though its frequency is not well documented in our country?, the economic burden it bears is not insignificant as it notably alters the quality of life of affected patients. Its diagnosis is generally clinical in nature, with further studies reserved only for the differential diagnoses of complications or tumour-like processes. Read More

    Orbital cellulitis and brain abscess - rare complications of maxillo-spheno-ethmoidal rhinosinusitis.
    Rom J Ophthalmol 2017 Apr-Jun;61(2):133-136
    ENT Department, Clinical Emergency County Hospital, Constanta, Romania.
    Sinus infections can be complicated by ocular infections and, in late phases, by brain parenchyma infection. The article debates the case of a 12-year-old patient suffering from paucisymptomatic maxillo-spheno-ethmoidal rhinosinusitis, which was later complicated by orbital cellulitis, ending with the development of a brain abscess. The treatment is complex, initially targeting the source of the infection through draining the collection by middle maxillary antrostomy and anterior posterior ethmoidectomy, then the ablation of the brain abscess and postoperatively with prolonged massive antibiotherapy. Read More

    Microbiology and antibiotic therapy of subperiosteal orbital abscess in children with acute ethmoiditis.
    Int J Pediatr Otorhinolaryngol 2018 Mar 2;106:91-95. Epub 2018 Feb 2.
    Service d'ORL Pédiatrique, Hôpital Femme Mère Enfants, Centre Hospitalier et Universitaire, Lyon, France; Service d'ORL, Hôpital Edouard Herriot, Centre Hospitalier et Universitaire, Lyon, France; Université de Lyon, Lyon, France; INSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Center, IMPACT Team, Lyon, France. Electronic address:
    Objective: The objective of this study was to investigate the microbiological cultures and the management of acute ethmoiditis complicated by subperiosteal orbital abscess (SPOA) in a pediatric population.

    Methods: The medical records of children under 18 years old was performed in a tertiary referral pediatric center from January 2009 to April 2017. Clinical examination, computed tomography scans, medical and surgical treatments were reviewed and compared to other studies in literature. Read More

    Combined immunosuppression and radiotherapy in thyroid eye disease (CIRTED): a multicentre, 2 × 2 factorial, double-blind, randomised controlled trial.
    Lancet Diabetes Endocrinol 2018 Apr 31;6(4):299-309. Epub 2018 Jan 31.
    Faculty of Health Sciences, University of Bristol, Bristol, UK; Thyroid Research Group, Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, UK; University Hospital of Wales, Cardiff, UK.
    Background: Standard treatment for thyroid eye disease is with systemic corticosteroids. We aimed to establish whether orbital radiotherapy or antiproliferative immunosuppression would confer any additional benefit.

    Methods: CIRTED was a multicentre, double-blind, randomised controlled trial with a 2 × 2 factorial design done at six centres in the UK. Read More

    [Applicability of Pedicled Coronoid Process and Temporal Muscle(Fascial)Combined(PCPTM)Flap for Reconstruction of Orbital Floor Defect Following Hemi-Maxillectomy for Advanced Maxillary Cancer - A Report of Two Cases].
    Gan To Kagaku Ryoho 2017 Nov;44(12):2035-2037
    Dept. of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine.
    We usually perform surgery for resectable oral and maxillofacial carcinomas. Following complete cancer resection, reconstruction of soft and hard tissues using various types of local flaps and/or vascularized free flaps is usually performed. The maxilla is composed of various anatomical structures. Read More

    [Orbital cellulitis complicated by subperiosteal abscess due to Streptococcus pyogenes infection].
    Bol Med Hosp Infant Mex 2017 Mar - Apr;74(2):134-140. Epub 2017 Mar 15.
    Departamento de Infectología Pediátrica, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, México.
    Background: Orbital cellulitis is an infectious disease that is very common in pediatric patients, in which severe complications may develop. Etiological agents related to this disease are Haemophilus influenzae B, Staphylococcus aureus, Streptococcus pneumoniae and Moraxella catarrhalis, which correspond to 95% of cases. Moreover, Streptococcus beta hemolytic and anaerobic microorganisms may also be present corresponding to < 5% of the cases. Read More

    Orbital sparganosis in an 8-year boy: a case report.
    BMC Ophthalmol 2018 Jan 22;18(1):13. Epub 2018 Jan 22.
    Eye Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 88 Jiefang Road, Hangzhou, 310009, People's Republic of China.
    Background: Sparganosis is one of the neglected but important food-borne parasitic zoonoses, with higher prevalence in Asian countries. The infection is commonly located in the subcutaneous tissue, brain, breast, and lung, but fewer reported infections involve the eye. Because the majority of patients with sparganosis are adults, it is likely to be missed in children. Read More

    The Reliability of the Transconjunctival Approach for Orbital Exposure: Measurement of Positional Changes in the Lower Eyelid.
    Arch Craniofac Surg 2017 Dec 23;18(4):249-254. Epub 2017 Dec 23.
    Department of Plastic and Reconstructive Surgery, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
    Background: Lower eyelid incisions are widely used for the orbital approach in periorbital trauma and aesthetic surgery. In general, the subciliary approach is known to cause disposition of the lower eyelid by scarring the anterior lamella in some cases. On the other hand, many surgeons believe that a transconjunctival approach usually does not result in such complications and is a reliable method. Read More

    Rhino-Orbital-Cerebral Mucormycosis: A Fatal Complication of Uncontrolled Diabetes Mellitus.
    Cureus 2017 Nov 13;9(11):e1841. Epub 2017 Nov 13.
    Department of Internal Medicine, MGM Medical College, Navi Mumbai, India.
    Mucormycosis is a progressively invasive disease, with a fatal outcome, on late presentation. A 38-year-old female presented with diabetic ketoacidosis with right eye ptosis and a frozen globe without any signs of inflammation, externally. She underwent transnasal endoscopic debridement of paranasal sinuses and exenteration of the right eye. Read More

    Sinogenic intracranial complications: is adalimumab a culprit?
    BMJ Case Rep 2018 Jan 17;2018. Epub 2018 Jan 17.
    Department of Head and Neck Surgery, Odense Universitetshospital, Odense, Denmark.
    We present two 11-year-old girls with chronic recurrent multifocal osteomyelitis, treated with adalimumab. Both developed severe intracranial complications to sinusitis. Patient 1 had been treated with adalimumab for 15 months when she developed acute sinusitis complicated by an orbital abscess, forehead swelling, a subdural empyema and osteomyelitis of the frontal bone. Read More

    Orbital Epstein-Barr Virus-Positive Polymorphic B-Cell Lymphoproliferative Disorder in an Apparently Immunocompetent Woman.
    Ocul Oncol Pathol 2017 Dec 11;4(1):61-65. Epub 2017 Aug 11.
    Department of Ophthalmology, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.
    We report a rare case of Epstein-Barr virus (EBV)-positive polymorphic B-cell lymphoproliferative disorder (LPD) involving the lacrimal gland of a 28-year-old, apparently immunocompetent woman. She presented with a chief complaint of orbital swelling and tenderness and was found to have a lesion involving the right lacrimal gland and distal superior and lateral rectus muscles. Histology of the lesion revealed histiocytes with pleomorphic nuclei, reactive lymphocytes, and scattered cells that resembled the Reed-Sternberg (R-S) cells of classical Hodgkin lymphoma. Read More

    Identification of anti-filarial leads against aspartate semialdehyde dehydrogenase of Wolbachia endosymbiont of Brugia malayi: combined molecular docking and molecular dynamics approaches.
    J Biomol Struct Dyn 2018 Feb 6:1-17. Epub 2018 Feb 6.
    a Department of Bioinformatics , Alagappa University , Karaikudi , India.
    Lymphatic filariasis is a debilitating vector borne parasitic disease that infects human lymphatic system by nematode Brugia malayi. Currently available anti-filarial drugs are effective only on the larval stages of parasite. So far, no effective drugs are available for humans to treat filarial infections. Read More

    Breakthrough mucormycosis after voriconazole use in a case of invasive fungal rhinosinusitis due to Curvularia lunata.
    Drug Discov Ther 2017 ;11(6):349-352
    Department of Medicine, All India Institute of Medical Sciences.
    Invasive fungal rhinosinusitis (FRS) is a potentially fatal illness requiring early diagnosis and aggressive treatment with surgery and antifungals. We report a case of chronic FRS in a recently diagnosed diabetic individual due to Curvularia lunata. Imaging revealed extension into the right orbit and right basifrontal lobe. Read More

    Utilising the Alexis Retractor for lateral orbital access, a case series.
    Orbit 2018 Jan 8:1-3. Epub 2018 Jan 8.
    c Ophthalmology , Royal Brisbane and Women's Hospital , Herston , Australia.
    Lateral orbital surgery is challenging and typically involves the use of multiple traction sutures and retractors. This case series describes a novel technique utilising the Alexis retractor to provide access for lateral orbital surgery. Thirteen cases were included and the surgical technique has been described and illustrated. Read More

    Conservative Management for Subperiosteal Orbital Abscess in Adults: A 20-Year Experience.
    Ann Otol Rhinol Laryngol 2018 Mar 3;127(3):162-166. Epub 2018 Jan 3.
    1 Department of Otolaryngology Head and Neck Surgery, Assaf Harofeh Medical Center, Zerifin, Israel.
    Objective: Orbital complications (OC) secondary to acute rhinosinusitis (ARS) in adults are less common than in children, with assumed worse outcome.

    Materials And Methods: Adults with OC secondary to ARS between 1994 and 2014 were reviewed retrospectively. Parameters recorded included age, gender, clinical symptoms and signs, computed tomography (CT) scan findings, duration of hospitalization, treatment before and during admission, cultures, and outcome. Read More

    Infection rates of MRSA in complicated pediatric rhinosinusitis: An up to date review.
    Int J Pediatr Otorhinolaryngol 2018 Jan 10;104:79-83. Epub 2017 Oct 10.
    Children's Mercy Hospital of Kansas City, United States.
    Introduction: Published studies have reported a rise in MRSA isolates in head and neck infections, but the microbiology of complicated pediatric rhinosinusitis is unclear. One study of such patients showed that MRSA isolates were seen only in the last three years of data collection, suggesting a possible recent increased prevalence. Given the public health concerns of increasing rates of antimicrobial resistance, the goal of this study was to investigate the microbiologic patterns and outcomes of complicated pediatric rhinosinusitis. Read More

    Knowledge and Attitude of Dental Surgeons about Ocular Complications Due to Dental Infection.
    J Pharm Bioallied Sci 2017 Nov;9(Suppl 1):S147-S153
    Department of Oral Pathology, Guru Gobind Singh College of Dental Sciences and Research Centre, Bhuranpur, Madhya Pradesh, India.
    Background: Ocular complications such as ophthalmia, defective vision, orbital cellulitis, and blindness (temporary or permanent) are rare complications due to dental infection. Currently, there is lack of guidelines in preventing and managing ocular problems. Hence, we assessed the dentist's knowledge and attitudes about ocular complications due to dental infection. Read More

    CNS aspergilloma mimicking tumors: Review of CNS aspergillus infection imaging characteristics in the immunocompetent population.
    J Neuroradiol 2017 Dec 19. Epub 2017 Dec 19.
    Department of Radiodiagnosis, JN medical College, Karnataka, India. Electronic address:
    Background And Purpose: CNS Aspergillosis is very rare and difficult to diagnose clinically and on imaging. Our objective was to elucidate distinct neuroimaging pattern of CNS aspergillosis in the immunocompetent population that helps to differentiate from other differential diagnosis.

    Methods: Retrospective analysis of brain imaging findings was performed in eight proven cases of central nervous system aspergillosis in immunocompetent patients. Read More

    Bilateral orbital marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue in a patient with hepatitis B virus infection.
    Am J Ophthalmol Case Rep 2017 Sep 18;7:27-30. Epub 2017 May 18.
    Department of Oculoplastic, Orbital & Lacrimal Surgery, Aichi Medical University Hospital, 1-1 Yazako-Karimata, Nagakute, Aichi, Japan.
    Purpose: To report a case of marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the bilateral orbit with chronic hepatitis B virus (HBV) infection.

    Observations: A 72-year-old man with chronic HBV infection presented with a bilateral proptosis with slight restriction of ocular motility for 9 months. Computed tomographic images showed well-defined, isodense masses in the bilateral superolateral orbit. Read More

    Case report of the family transmission of orbital cellulitis.
    Am J Ophthalmol Case Rep 2017 Jun 20;6:52-54. Epub 2017 Feb 20.
    Sainte-Justine Hospital, Montreal University, Canada.
    Purpose: This is a case report of an unusual case of the family transmission of infection in three siblings. One brother contracted the infection which resulted in orbital cellulitis of two of his siblings, in the absence of anatomical or immunological predisposing factors.

    Observations: A young boy contracted an uncomplicated upper respiratory tract infection. Read More

    Optic neuritis in dogs: 96 cases (1983-2016).
    Vet Ophthalmol 2017 Dec 18. Epub 2017 Dec 18.
    Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC, 27607, USA.
    Objective: To characterize ocular and neurologic findings, causes, and treatment outcomes of dogs with optic neuritis.

    Procedure: Medical records from dogs with a diagnosis of optic neuritis at North Carolina State University, College of Veterinary Medicine, Veterinary Hospital between 1983 and 2016 were reviewed.

    Results: Ninety-six cases (20 unilateral, 76 bilateral), comprised of 38 males and 58 females with a mean age of 6. Read More

    Orbital Cellulitis Presenting as Giant Cell Arteritis: A Case Report.
    Acta Neurol Taiwan 2017 Jun;26(2):72-75
    Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China.
    Purpose: To present a case of orbital cellulitis initially mimicking giant cell arteritis.

    Case Report: An 80-year-old man with a history of hypertension and type 2 diabetes mellitus was referred with a prominent progressive headache over the right temporal and periorbital areas. Non-contrast brain CT results were normal, but ESR was elevated. Read More

    Orbital cellulitis.
    Surv Ophthalmol 2017 Dec 15. Epub 2017 Dec 15.
    Department of Ophthalmology, University of Thessaly, Larissa, Greece. Electronic address:
    Orbital cellulitis (OC) is an inflammatory process that involves the tissues located posterior to the orbital septum within the bony orbit, but the term generally is used to describe infectious inflammation. It manifests with erythema and edema of the eyelids, vision loss, fever, headache, proptosis, chemosis, and diplopia. OC usually originates from sinus infection, infection of the eyelids or face, and even hematogenous spread from distant locations. Read More

    Inflammatory foreign body reaction caused by resorbable materials used for orbital fractures repair: A case report.
    Medicine (Baltimore) 2017 Dec;96(49):e8822
    aDepartment of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of MedicinebShanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
    Rationale: Resorbable materials have been recommended for orbital fractures repair. Many literatures reported the advantages of resorbable materials in clinical applications, but few reports about complications.

    Patient Concerns: In this study, we encountered a 14-year-old boy treated for the orbital fracture by using resorbable plate, in whom inflammatory foreign body reaction was detected. Read More

    Mesoporous silica-based bioactive glasses for antibiotic-free antibacterial applications.
    Mater Sci Eng C Mater Biol Appl 2018 Feb 10;83:99-107. Epub 2017 Nov 10.
    Institute of Biomaterials, University of Erlangen-Nuremberg, Cauerstrasse 6, 91058 Erlangen, Germany. Electronic address:
    Bioactive glasses (BGs) are being used in several biomedical applications, one of them being as antibacterial materials. BGs can be produced via melt-quenching technique or sol-gel method. Bactericidal silver-doped sol-gel derived mesoporous silica-based bioactive glasses were reported for the first time in 2000, having the composition 76SiO-19CaO-2PO-3AgO (wt%) and a mean pore diameter of 28nm. Read More

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