2,071 results match your criteria Orbital Infection Imaging


Extent of craniofacial fungal osteomyelitis in a ketoacidotic patient may predict optic nerve involvement: A case report.

Int J Surg Case Rep 2022 Jun 13;96:107299. Epub 2022 Jun 13.

Department of Head and Neck Surgery, Facial Plastic and Reconstructive Surgery, University of Texas Rio Grande Valley, United States of America.

Introduction: Mucormycosis is an opportunistic mycosis common in poorly-controlled insulin dependent diabetic patients particularly with ketoacidosis. Fungal osteomyelitis is a life-threatening condition affectation of the nose and paranasal sinuses within the orofacial region.

Presentation Of Case: We present a 63-year-old diabetic male patient with maxillary mucormycotic osteomyelitis threatening his better seeing eye and review the clinical symptoms, relevant imaging, and management. Read More

View Article and Full-Text PDF

Analysis of COVID-19-associated rhino-orbital-cerebral mucormycosis patients in a tertiary care center in Northern India.

Indian J Ophthalmol 2022 Jun;70(6):2163-2168

Department of Ophthalmology, Sarojini Naidu Medical College, Agra, Uttar Pradesh, India.

Purpose: An unprecedented surge has been noted in rhino-orbital-Cerebral mucormycosis (ROCM) in times of current COVID-19 pandemic. The present prospective study aims to evaluate clinico-epidemiological profile, risk factors, management, and outcome of the cases of ROCM that presented to our tertiary care center during the study period from April to June 2021.

Methods: All patients were subjected to complete history taking, ophthalmological examination, and imaging studies. Read More

View Article and Full-Text PDF

Anti-GQ1b Antibody Syndrome with Visual Impairment: A Retrospective Case Series.

J Integr Neurosci 2022 Apr;21(3):81

Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, 510080 Guangzhou, Guangdong, China.

Background: Anti-GQ1b antibody syndrome referred to a clinical spectrum characterized by acute onset of ataxia, ophthalmoplegia and areflexia, while visual deterioration was rarely reported in terms of ocular disorders. This study aimed to describe the clinical characteristics of anti-GQ1b antibody syndrome with visual impairment.

Methods: The database at the First Affiliated Hospital of Sun Yat-sen University was searched from 2014 to 2020. Read More

View Article and Full-Text PDF

A case of total ophthalmoplegia associated with a COVID-19 infection: case report.

Oxf Med Case Reports 2022 May 23;2022(5):omac050. Epub 2022 May 23.

Department of Ophthalmology, Aleppo University Hospital, Aleppo, Syria.

We are presenting a rare case of an acute complete external ophthalmoplegia with positive polymerase chain reaction (PCR) for SARS-CoV-2. Our case is the first case that depicts development of Tolosa-Hunt Syndrome (THS) following infection with COVID-19, with a challenging diagnosis and spontaneous improvement. A 65-year-old diabetic female presented with a complete external ophthalmopegia in the left eye and a severe left-sided headache. Read More

View Article and Full-Text PDF

Rhino-Orbital-Cerebral Mucormycosis in a Young Diabetic Patient with COVID-19 in Ethiopia: A Case Report.

Int Med Case Rep J 2022 19;15:251-257. Epub 2022 May 19.

Ophthalmologist, Department of Ophthalmology, MOH Eka Kotebe General Hospital, Addis Ababa, Ethiopia.

Background: There has been a rise in secondary invasive fungal infections reported in COVID-19 patients globally. We report the first published case of COVID-19 associated rhino-orbital-cerebral mucormycosis in Africa in a newly diagnosed diabetic female who presented with diabetic ketoacidosis (DKA) and discuss the prevalence and risk factors of fungal co-infection with the clinical presentation, diagnosis, and management of mucormycosis in COVID-19.

Case Presentation: A 39 years old female patient was admitted to ICU with a diagnosis of severe COVID-19 and newly diagnosed diabetes mellitus (DM) with DKA based on HgbA1c of 13. Read More

View Article and Full-Text PDF

MR imaging spectrum in COVID associated Rhino-Orbito-Cerebral mucormycosis with special emphasis on intracranial disease and impact on patient prognosis.

Eur J Radiol 2022 Jul 6;152:110341. Epub 2022 May 6.

Department of Ophthalmology, Maulana Azad Medical College and Guru Nanak Eye Centre, New Delhi 110002, India.

In the wake of the ongoing Coronavirus Disease 2019 (COVID-19) pandemic, a new epidemic of COVID associated mucormycosis (CAM) emerged in India. Early diagnosis and prompt treatment of this deadly disease are of paramount importance in improving patient survival. MRI is the cornerstone of diagnosis of early extrasinus disease, particularly intracranial complications which have traditionally been associated with a high mortality rate. Read More

View Article and Full-Text PDF

Factors associated with surgery and imaging characteristics in severe orbital infections.

J Pediatr 2022 May 11. Epub 2022 May 11.

The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada; Child Health Evaluative Sciences, SickKids Research Institute, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, The University of Toronto, Toronto, Ontario, Canada.

Objectives: To evaluate risk factors associated with surgical intervention and subperiosteal/orbital abscess in hospitalized children with severe orbital infections.

Study Design: We conducted a multicenter cohort study of children 2 months to 18 years hospitalized with periorbital or orbital cellulitis from 2009 to 2018 at 10 hospitals in Canada. Clinical details were extracted, and patients were categorized as undergoing surgical or medical-only management. Read More

View Article and Full-Text PDF

ACR Appropriateness Criteria® Sinonasal Disease: 2021 Update.

J Am Coll Radiol 2022 05;19(5S):S175-S193

Specialty Chair, Atlanta VA Health Care System and Emory University, Atlanta, Georgia.

This article presents guidelines for initial imaging utilization in patients presenting with sinonasal disease, including acute rhinosinusitis without and with suspected orbital and intracranial complications, chronic rhinosinusitis, suspected invasive fungal sinusitis, suspected sinonasal mass, and suspected cerebrospinal fluid leak. CT and MRI are the primary imaging modalities used to evaluate patients with sinonasal disease. Given its detailed depiction of bony anatomy, CT can accurately demonstrate the presence of sinonasal disease, bony erosions, and anatomic variants, and is essential for surgical planning. Read More

View Article and Full-Text PDF

Unnecessary Use of Corticosteroids for managing early mild symptoms of COVID-19 may lead to Rhino-ortibal-cerebral mucormycosis in Patients with Diabetes - a case series from Lahore, Pakistan.

Ther Adv Infect Dis 2022 Jan-Dec;9:20499361221097417. Epub 2022 May 6.

INEOS Oxford Institute for AMR Research, University of Oxford, UK.

Rhino-orbital-cerebral mucormycosis (ROCM), a rare but fatal fungal infection, has recently emerged as a serious complication after corticosteroids therapy in COVID-19 patients, predominantly in diabetic and immunocompromised patients. The World Health Organization (WHO) COVID-19 current guidelines recommend corticosteroids administration in hospitalized COVID-19 patients requiring supplementary oxygen or mechanical ventilation. Herein, we report a case series of seven patients with COVID-19; three mild, three moderate, and one severe, from Lahore, Pakistan; all were using corticosteroids for managing their early mild symptoms of COVID-19 at home for around 2-3 weeks without a physician's advise, presented, and admitted with ROCM to Mayo hospital, Lahore, from March to June 2021. Read More

View Article and Full-Text PDF

Posterior scleral perforation due to endogenous endophthalmitis in a pregnant with selective IgA deficiency.

Rom J Ophthalmol 2022 Jan-Mar;66(1):97-100

Department of Oculoplastic and Orbital Surgery, Hospital Universitario y Politécnico La Fe, Valencia, Spain.

We present the case of a 35-year-old female patient, pregnant in her third trimester, with no ophthalmologic history of interest and a medical history of IgA deficiency syndrome with bronchiectasis as the only symptomatology, who came to another center with clinical symptoms of ocular discomfort. She was initially diagnosed with anterior uveitis and treated with topical and periocular corticosteroids. Edema and palpebral erythema appeared a few days later and she was diagnosed with idiopathic orbital inflammation and was treated with intravenous (I. Read More

View Article and Full-Text PDF

An Unusual Etiology of Lemierre-Like Syndrome: Preseptal Cellulitis due to Methicillin-Resistant .

Open Forum Infect Dis 2022 May 18;9(5):ofac143. Epub 2022 Apr 18.

Division of Infectious Disease, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

Lemierre's syndrome (LS) is a rare and potentially fatal condition that predominantly affects young adults with oropharyngeal infection. is the usual etiology and classically causes internal jugular vein septic thrombophlebitis, frequently complicated by septic emboli to several organs (most classically to the lungs). Lemierre-like syndrome (LLS) describes the same constellation of symptoms and pathophysiology as Lemierre's syndrome; however, spp. Read More

View Article and Full-Text PDF

Case Report: Overlapping Syndrome of Anti-NMDAR Encephalitis and MOG Inflammatory Demyelinating Disease in a Patient With Human Herpesviruses 7 Infection.

Front Immunol 2022 22;13:799454. Epub 2022 Apr 22.

Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.

Objectives: This study reported a case of overlapping anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis and myelin oligodendrocyte glycoprotein (MOG) inflammatory demyelinating disease with human herpesviruses 7 (HHV-7) infection.

Methods: The detailed clinical characteristics, neuroimaging features, and outcomes of the patient were collected. Polymerase chain reaction (PCR), cell-based assay (CBA) and the tissue-based indirect immunofluorescence assay (TBA) were used for diagnosis. Read More

View Article and Full-Text PDF

Misdiagnosis of fungal infections of the orbit.

Can J Ophthalmol 2022 May 4. Epub 2022 May 4.

From the Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa. Electronic address:

Objective: To evaluate the accuracy of the initial diagnosis in the case of fungal infections of the orbit and identify factors that may influence patient outcomes.

Methods: An institutional review board-approved retrospective chart review was conducted across 2 large academic centres to identify cases of fungal infections involving the orbit from January 1, 1998, to November 15, 2019. Data collected included patient demographics, past medical history, examination findings, diagnosis, treatment, imaging, and outcomes. Read More

View Article and Full-Text PDF

Features of ophthalmic, magnetic resonance imaging, and histopathology of a feline case of idiopathic sclerosing orbital pseudotumor.

Vet Med Sci 2022 May 3. Epub 2022 May 3.

Institute of Veterinary Clinical Sciences, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.

In the present report, we describe a case of sclerosing orbital pseudotumor in an 11-year-old castrated male American Shorthair cat. Ophthalmic exam showed lagophthalmos, retracted right upper eyelid, and resistant to retropulsion in his right eye. Under magnetic resonance imaging (MRI) scans, increased volume of the extraocular muscles (EOMs) of the right eye was prominent. Read More

View Article and Full-Text PDF

[Diagnosis and treatment of subperiosteal orbital abscess].

Ugeskr Laeger 2022 Apr;184(17)

Øre-, Næse-, Halskirurgi, Aarhus Universitetshospital.

Subperiosteal orbital abscess is a complication of acute bacterial sinusitis. In this review, we summarise the theoretical background and highlight the importance of a fast diagnostic workup. The treatment of acute sinusitis with involvement of an eye is antibiotic therapy and daily evaluation by both an ophtalmologist and a rhinologist. Read More

View Article and Full-Text PDF

Management of intraorbital infections in the pediatric emergency department.

Eur J Pediatr 2022 Jul 27;181(7):2741-2746. Epub 2022 Apr 27.

Pediatric Emergency Department, Wilf Children's Hospital, Shaare Zedek Medical Center, 12 Shmuel Bait Street, 9103102, Jerusalem, Israel.

Intraorbital infections may lead to severe complications, necessitating rapid diagnosis and intervention. The decision process regarding the need for emergent imaging and possible surgical intervention is unclear in the literature. This retrospective cohort study included two major pediatric emergency departments in Israel between 2010 and 2020. Read More

View Article and Full-Text PDF

Posterior Ischemic Optic Neuropathy in the Setting of Cocaine-Induced Orbital and Sinonasal Inflammation.

Ophthalmic Plast Reconstr Surg 2022 Apr 25. Epub 2022 Apr 25.

Ophthalmic Plastic Surgery Service, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, U.S.A.

Intranasal cocaine abuse can lead to significant sinus and orbital complications, including optic neuropathy. A 46-year-old man with a history of recurrent cocaine-induced sino-orbital inflammation and infection with bony destruction presented with acute, painless, vision loss. Examination revealed no light perception vision. Read More

View Article and Full-Text PDF

Persistent olfactory dysfunction after COVID-19 is associated with reduced perfusion in the frontal lobe.

Acta Neurol Scand 2022 Apr 25. Epub 2022 Apr 25.

Department of Radiology, Clínico San Carlos, Health Research Institute "San Carlos" (IdISSC), Universidad Complutense de Madrid, Madrid, Spain.

Background: Olfactory dysfunction is common during SARS-CoV-2 infection. The pathophysiology of the persistence of this symptom and the potential relationship with central nervous system involvement is unknown.

Aim Of The Study: To evaluate the neural correlates of persistent olfactory dysfunction in a series of patients with post-COVID syndrome. Read More

View Article and Full-Text PDF

Sino-Orbital Aspergillosis in a Kidney Transplant Recipient.

Case Rep Transplant 2022 14;2022:5946446. Epub 2022 Apr 14.

Division of Nephrology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.

Sino-orbital aspergillosis is a rare and severe infection mostly seen in immunocompromised individuals in which diagnosis may be challenging with potentially life-threatening consequences. Infection usually starts in the paranasal sinuses with secondary spreading to the adjacent orbits. Here, we report the case of a kidney transplant recipient who presented with proven invasive sino-orbital aspergillosis resulting in irreversible loss of vision despite surgical management and antifungal therapy. Read More

View Article and Full-Text PDF

Clinical Profile of Central Nervous System Involvement in Patients with Rhino Orbital Cerebral Mucormycosis.

J Assoc Physicians India 2022 Apr;70(4):11-12

Bangalore Medical College, Kalaburgi.

Mucormycosis is life threatening fungal infection that occurs in immunocompromised patients. Patients at risk are those with poorly controlled diabetes mellitus, immunosuppressed patients such as those undergoing treatment for hematological cancer or recipients of solid organ and hematopoietic stem cell transplantation. COVID 19 infection is known to produce a state of hyper inflammation with release of various cytokines this state of immune dysfunction is associated with development of opportunistic infections, of which Mucormycosis is on the rise currently. Read More

View Article and Full-Text PDF

Storm of a rare opportunistic life threatening mucormycosis among post COVID-19 patients: A tale of two pathogens.

Int J Crit Illn Inj Sci 2022 Jan-Mar;12(1):38-46. Epub 2022 Mar 24.

Department of Community Medicine, All India Institute of Medical Sciences, Mangalagiri, Andhra Pradesh, India.

Mucormycosis is a rare but life-threatening opportunistic fungal infection caused by a group of molds that belong to Zygomycetes of the order Mucorales. These fungi are found in the environment such as soil, decaying vegetation, and organic matters. Sporangiospores present in the environment enter the human body through inhalation or direct skin inoculation by trauma or ingestion and result in pulmonary, cutaneous, and gastrointestinal mucormycosis, respectively, in immunocompromised hosts. Read More

View Article and Full-Text PDF

Management options for orbital complications of acute rhinosinusitis in pediatric patients.

Am J Otolaryngol 2022 May-Jun;43(3):103452. Epub 2022 Apr 6.

Department of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain; University of Oviedo, Instituto de Investigación Sanitaria del Principado de Asturias, IUOPA, CIBERONC, Oviedo, Spain.

Objectives: Acute bacterial rhinosinusitis (ABRS) is a common pediatric condition. Despite its tendency to heal without complications, orbital complications (OC) are seen in 6% of patients and can cause vision impairment and put life at risk. Current treatment of this complications involves systemic antibiotics with or without surgical drainage, remaining controversial the use of corticosteroids. Read More

View Article and Full-Text PDF

Orbital Metastasis From Gastric Cancer Presenting as Orbital Cellulitis With Ptosis.

J Craniofac Surg 2022 Mar-Apr 01;33(2):e133-e135

Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.

Abstract: We report a rare case of orbital metastasis that originated from gastric carcinoma, which presented as orbital cellulitis with ptosis. Orbital metastasis accounts for about only 1% to 13% of orbital tumors. Orbital metastasis in orbital soft tissue or bony structures is very uncommon. Read More

View Article and Full-Text PDF

Sinogenic polymicrobial anaerobic orbital cellulitis: the importance of source control and broad empirical antibiotics.

BMJ Case Rep 2022 Mar 29;15(3). Epub 2022 Mar 29.

Department of Microbiology, NHS Forth Valley, Larbert, UK

A man in his twenties with a history of recurrent sinusitis was urgently referred to the emergency department (ED) by an out-of-hours general practitioner following a 2-day history of increasing right eye pain, redness and swelling after a week of coryzal symptoms. He denied visual impairment and any history of recent dental pain or procedures. Initial assessment in ED noted fever, tachycardia and hypotension. Read More

View Article and Full-Text PDF

Orbital Plasmacytoma in a Young Patient With HIV Presenting as Multiple Cranial Nerve Palsy.

Neurology 2022 05 25;98(19):806-807. Epub 2022 Mar 25.

From the Syrian Lebanese Hospital (P.E.L.F.), São Paulo; Federal University of Southern Border (C.K.), Passo Fundo; Emílio Ribas Infectology Institute (M.V.F., L.d.O.P., J.E.V., A.C.P.O.); and University of Sao Paulo Hospital of Clinics (J.E.V.), Brazil.

View Article and Full-Text PDF

Orbital compartment syndrome secondary to subperiosteal abscess initiated by barotrauma.

BMJ Case Rep 2022 Mar 24;15(3). Epub 2022 Mar 24.

Oral Maxillofacial Surgery, Auckland District Health Board, Auckland, New Zealand

This case report demonstrates an unusual complication of bacterial rhinosinusitis, causing orbital compartment syndrome from a presumed barotrauma. We postulate that the patient developed unilateral optic neuropathy, as a result of orbital compartment syndrome, secondary to orbital subperiosteal abscess following direct communication with the ethmoid sinus initiated by barotrauma. It is supported by evidence of a bony dehiscence on the lamina papyracea of the medial orbital wall with sudden onset of pain, proptosis and visual symptoms during flight. Read More

View Article and Full-Text PDF

Neglected Case of Primary Intraorbital Hydatid Cyst.

Neurol India 2022 Jan-Feb;70(1):337-339

Department of Neurosurgery, Rajendra Institute of Medical Sciences, Ranchi, India.

Background: Hydatid cyst is a parasitic infection caused by Echinococcus granulosus and human is an accidental host. Liver and lungs are the most widely recognized organ of association but relatively low in other organs. Orbital involvement of the hydatid cyst is rare. Read More

View Article and Full-Text PDF

Coronavirus Disease 2019 (COVID-19)-Associated Rhino-Orbito-Cerebral Mucormycosis: A Multi-Institutional Retrospective Study of Imaging Patterns.

World Neurosurg 2022 Jun 4;162:e131-e140. Epub 2022 Mar 4.

Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India. Electronic address:

Background: Mucormycosis infection of the maxillofacial region and brain has been associated with coronavirus disease 2019 (COVID-19) infection. Mucormycosis was relatively a rare infection before COVID-19, and imaging findings are not very well described.

Materials And Methods: A retrospective imaging study of 101 patients diagnosed with COVID-19-associated mucormycosis by histopathology and/or culture was performed. Read More

View Article and Full-Text PDF

CT Imaging Features in Acute Invasive Fungal Rhinosinusitis- Recalling the Oblivion in the COVID Era.

Curr Probl Diagn Radiol 2022 Feb 7. Epub 2022 Feb 7.

Department of Otorhinolaryngology (ENT), Maulana Azad Medical College, New Delhi, India.

Objective: Recent pandemic of COVID19 infection has witnessed a re-emergence of invasive fungal sinusitis especially of the Mucor species, which has been a rare entity in the pre covid era. Covid associated mucormycosis (CAM) is one of the dreaded and fatal complications which has surfaced up and early diagnosis is critical for management and survival .It is identified to affect both subset of patients, those with active COVID-19 infection and those who have recovered from the disease in the last 4-6 weeks. Read More

View Article and Full-Text PDF
February 2022

Imaging Findings of Pediatric Orbital Masses and Tumor Mimics.

Radiographics 2022 May-Jun;42(3):880-897. Epub 2022 Mar 4.

From the Departments of Radiology (A.K.J., J.B.G., L.J.E., G.B.L., J.C.B., W.B., V.M.S.), Ophthalmology (L.A.D.), Neurology (G.F.K.), Neurosurgery (W.B.), and Radiation Oncology (N.N.L.), Mayo Clinic, 200 1st St SW, Rochester, MN 55905.

Pediatric orbital masses are not common but encompass a wide spectrum of benign and malignant entities that range from developmental anomalies to primary and secondary orbital malignancies and metastatic disease. Certain orbital tumors are unique to pediatric patients, such as retinoblastoma and neuroblastoma. Clinical symptoms and signs are often insufficient to differentiate between orbital lesions, and imaging is essential for narrowing the diagnostic considerations and determining the most appropriate management strategy. Read More

View Article and Full-Text PDF